CN104491645A - External use plaster used for treating bone diseases - Google Patents

External use plaster used for treating bone diseases Download PDF

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Publication number
CN104491645A
CN104491645A CN201510046365.2A CN201510046365A CN104491645A CN 104491645 A CN104491645 A CN 104491645A CN 201510046365 A CN201510046365 A CN 201510046365A CN 104491645 A CN104491645 A CN 104491645A
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parts
radix
rhizoma
herba
grams
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刘建新
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
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    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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Abstract

The invention relates to an external use plaster used for treating bone diseases. The external use plaster comprises, by weight, 10 parts to 30 parts of crude sichuan aconite roots, 10 parts to 30 parts of arisaema heterophyllum blume, 10 parts to 30 parts of siebold wildginger, 10 parts to 30 parts of angelica sinensis, 10 parts to 20 parts of drynaria total flavonoids, 10 parts to 20 parts of Chinese polyphaga, 10 parts to 20 parts of momordica cochinchinensis, 10 parts to 30 parts of lumbricus, 10 parts to 30 parts of stiff silkworms, 10 parts to 20 parts of semen brassicae, 10 parts to 30 parts of pericarpium citri reticulatae viride, 10 parts to 30 parts of rhizoma kaempferiae, 10 parts to 20 parts of dipsacus asperoids, 10 parts to 20 parts of pollen typhae, 10 parts to 20 parts of radix paeoniae rubra, 10 parts to 20 parts of rheum officinale, 10 parts to 30 parts of olibanum, 10 parts to 30 parts of myrrh, 10 parts to 20 parts of pangolin and 10 parts to 30 parts of nard. The traditional Chinese medicine components influence one another, have synergistic effects, can clear wind-damp, dispel cold and dissolve knots, dredge channels and arrive at joints, are remarkable in curative effect and are quite worthy of popularization.

Description

A kind of externally applied ointment for the treatment of osteopathia
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of externally applied ointment of nursing for treating osteopathia.
Background technology
Scapulohumeral periarthritis is called scapulohumeral periarthritis for short again in clinical medicine, and its main clinical symptoms is shoulder pain and the dyskinesia.It refers to the acute and chronic trauma of shoulder joint and the soft tissue such as tendon, ligament, synovial bursa around thereof, or degeneration, causes local and produces aseptic inflammation, thus causes shoulder pain and dysfunction to be a kind of disease of primary symptom.The traditional Chinese medical science is thought, primary disease be wind, cold, wet three heresy invasion and attack shoulder channels and hyperamization coagulate not all right, the stagnation of QI is obstructed and pain.
Summary of the invention
The object of this invention is to provide a kind of externally applied ointment for the treatment of osteopathia.
In order to realize object of the present invention, the invention provides a kind of externally applied ointment for the treatment of osteopathia, it comprises the material of following weight portion: Radix Aconiti 10-30 part, Rhizoma Arisaematis 10-30 part, Herba Asari 10-30 part, Radix Angelicae Sinensis 10-30 part, Rhizoma Drynariae 10-20 part, Eupolyphaga Seu Steleophaga 10-20 part, Semen Momordicae 10-20 part, Pheretima 10-30 part, Bombyx Batryticatus 10-30 part, Semen Sinapis Albae 10-20 part, Pericarpium Citri Reticulatae Viride 10-30 part, Rhizoma Kaempferiae 10-30 part, Radix Dipsaci 10-20 part, Pollen Typhae 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Olibanum 10-30 part, Myrrha 10-30 part, Squama Manis 10-20 part and Radix Et Rhizoma Nardostachyos 10-30 part.
Preferably, the externally applied ointment for the treatment of osteopathia of the present invention comprises the material of following weight portion: Radix Aconiti 20 parts, Rhizoma Arisaematis 20 parts, Herba Asari 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Drynariae 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Semen Momordicae 15 parts, Pheretima 20 parts, Bombyx Batryticatus 20 parts, Semen Sinapis Albae 15 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Kaempferiae 20 parts, Radix Dipsaci 15 parts, Pollen Typhae 15 parts, Radix Paeoniae Rubra 15 parts, Radix Et Rhizoma Rhei 15 parts, Olibanum 20 parts, Myrrha 20 parts, Squama Manis 15 parts and Radix Et Rhizoma Nardostachyos 20 parts.
Preferably, the externally applied ointment for the treatment of osteopathia of the present invention also comprises the material of following weight portion: five leaf potatos 15 parts, Herba Fimbristylis dichotomae 10 parts, Herba Christiae Obcordatae 12 parts, Herba Briggsiae Chienii 15 parts, Indigo Naturalis 20 parts, Caulis Seu Folium Lespedezae Bicoloris 12 parts, Polygonum cynanchoides Hemsl. 15 parts, Herba lespedezae virgatae 10 parts, Flos Inulae 15 parts, Herba malachii aquatici 10 parts and Salvia japonica Thunb. 9 parts.
Preferably, described externally applied ointment can be ointment plaster or plaster liniment.
The present invention also provides the purposes of compositions in the Chinese medicine of preparation treatment rheumatism muscle and joint disease, described compositions comprises the material of following weight portion: Radix Aconiti 10-30 part, Rhizoma Arisaematis 10-30 part, Herba Asari 10-30 part, Radix Angelicae Sinensis 10-30 part, Rhizoma Drynariae 10-20 part, Eupolyphaga Seu Steleophaga 10-20 part, Semen Momordicae 10-20 part, Pheretima 10-30 part, Bombyx Batryticatus 10-30 part, Semen Sinapis Albae 10-20 part, Pericarpium Citri Reticulatae Viride 10-30 part, Rhizoma Kaempferiae 10-30 part, Radix Dipsaci 10-20 part, Pollen Typhae 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Olibanum 10-30 part, Myrrha 10-30 part, Squama Manis 10-20 part and Radix Et Rhizoma Nardostachyos 10-30 part.
Preferably, described compositions comprises the material of following weight portion: Radix Aconiti 20 parts, Rhizoma Arisaematis 20 parts, Herba Asari 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Drynariae 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Semen Momordicae 15 parts, Pheretima 20 parts, Bombyx Batryticatus 20 parts, Semen Sinapis Albae 15 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Kaempferiae 20 parts, Radix Dipsaci 15 parts, Pollen Typhae 15 parts, Radix Paeoniae Rubra 15 parts, Radix Et Rhizoma Rhei 15 parts, Olibanum 20 parts, Myrrha 20 parts, Squama Manis 15 parts and Radix Et Rhizoma Nardostachyos 20 parts.
Preferably, described compositions also comprises the material of following weight portion: five leaf potatos 15 parts, Herba Fimbristylis dichotomae 10 parts, Herba Christiae Obcordatae 12 parts, Herba Briggsiae Chienii 15 parts, Indigo Naturalis 20 parts, Caulis Seu Folium Lespedezae Bicoloris 12 parts, Polygonum cynanchoides Hemsl. 15 parts, Herba lespedezae virgatae 10 parts, Flos Inulae 15 parts, Herba malachii aquatici 10 parts and Salvia japonica Thunb. 9 parts.
Preferably, described externally applied ointment can be ointment plaster or plaster liniment.
Chinese medicine composition of the present invention interacts, and synergism is evident in efficacy, highly widelys popularize.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment 1 plaster liniment of the present invention
Take Radix Aconiti 20 grams, Rhizoma Arisaematis 20 grams, Herba Asari 20 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Drynariae 15 grams, Eupolyphaga Seu Steleophaga 15 grams, Semen Momordicae 15 grams, Pheretima 20 grams, Bombyx Batryticatus 20 grams, Semen Sinapis Albae 15 grams, 20 grams, Pericarpium Citri Reticulatae Viride, Rhizoma Kaempferiae 20 grams, Radix Dipsaci 15 grams, Pollen Typhae 15 grams, Radix Paeoniae Rubra 15 grams, Radix Et Rhizoma Rhei 15 grams, Olibanum 20 grams, Myrrha 20 grams, Squama Manis 15 grams and Radix Et Rhizoma Nardostachyos 20 grams, pulverize, cross 30 mesh sieves, add dehydrated alcohol 4000 milliliters, heating 3 hours under the condition of backflow, be cooled to room temperature, adding water to alcohol content is 75 volume %, at room temperature, hold over night, filter, make filtrate evaporate to dryness, pulverize, add 500 grams, vaseline, mix homogeneously, obtain.
Embodiment 2 plaster liniment of the present invention
Take Radix Aconiti 20 grams, Rhizoma Arisaematis 20 grams, Herba Asari 20 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Drynariae 15 grams, Eupolyphaga Seu Steleophaga 15 grams, Semen Momordicae 15 grams, Pheretima 20 grams, Bombyx Batryticatus 20 grams, Semen Sinapis Albae 15 grams, 20 grams, Pericarpium Citri Reticulatae Viride, Rhizoma Kaempferiae 20 grams, Radix Dipsaci 15 grams, Pollen Typhae 15 grams, Radix Paeoniae Rubra 15 grams, Radix Et Rhizoma Rhei 15 grams, Olibanum 20 grams, Myrrha 20 grams, Squama Manis 15 grams, Radix Et Rhizoma Nardostachyos 20 grams, five leaf potatos 15 grams, Herba Fimbristylis dichotomae 10 grams, Herba Christiae Obcordatae 12 grams, Herba Briggsiae Chienii 15 grams, Indigo Naturalis 20 grams, Caulis Seu Folium Lespedezae Bicoloris 12 grams, Polygonum cynanchoides Hemsl. 15 grams, Herba lespedezae virgatae 10 grams, Flos Inulae 15 grams, Herba malachii aquatici 10 grams and Salvia japonica Thunb. 9 grams, pulverize, cross 30 mesh sieves, add dehydrated alcohol 4000 milliliters, heating 3 hours under the condition of backflow, be cooled to room temperature, adding water to alcohol content is 75 volume %, at room temperature, hold over night, filter, make filtrate evaporate to dryness, pulverize, add 500 grams, vaseline, mix homogeneously, obtain.
Experimental example
Diagnostic criteria
Shoulder pain, to be night very, is often waken up bitterly, but less swelling.Shoulder mobility is obviously limited, notably takes on arm amyotrophy, extensive tenderness under acromion, shoulder abduction, upper act, outward turning, after stretch, action that back is lifted is limited, occurs typically " shouldering shoulder " phenomenon, actions such as can not undressing, comb one's hair, wash one's face.X-ray is taken the photograph sheet and mostly is negative, the visible osteoporosis of course of disease person of a specified duration or slight hyperosteogeny.
Selector close standard of stating patient 58 example, male 26 example, women 32 example; Age 37-68 year, year mean age (54.7 ± 5.6); The course of disease is 7 examples within 1 month, and the 1-3 month 7 is routine, and the 4-6 month 25 is routine, and the 6-12 month 16 is routine, more than 1 year 3 example, average course of disease (7.5 ± 3.5) moon; Wherein left side scapulohumeral periarthritis 24 example, right side scapulohumeral periarthritis 22 example, bilateral 12 example.Be two groups by patient, be respectively treatment group 1 and treatment group 2, often group has 29 routine patients.Two groups of Genders, age, the course of disease, symptom there are no significant difference, have comparability (P > 0.05).
Treatment group 1 uses the plaster liniment of preparation in embodiment 1 to treat, every day twice, and each use 15 grams of uniform application, at shoulder pain position, are treated 20 days continuously.
Treatment group 2 uses the plaster liniment of preparation in embodiment 2 to treat, every day twice, and each use 15 grams of uniform application, at shoulder pain position, are treated 20 days continuously.
Criterion of therapeutical effect
According to the criterion of therapeutical effect river of " new Chinese medicine guideline of clinical investigations " (Ministry of Health of the People's Republic of China work out, 1997 the 3rd volume) about " scapulohumeral periarthritis ".1. cure: shoulder pain disappears, shoulder mobility scope recovers normal.2. effective: shoulder pain is alleviated obviously, and shoulder mobility scope is improved obviously.3. effective: shoulder pain is alleviated substantially, shoulder mobility range section improves.4. invalid: clinical symptoms is without change.
Statistical method
Utilize SPSS 15.0 software to process and analyze to experimental data, measurement data is with mean ± standard deviation represent, adopt t inspection, enumeration data adopts x 2inspection, P < 0.05 represents that difference has statistical significance.
Result
Through treatment, for treatment group 1, cure 10 examples, effective 8 examples, effective 7 examples, invalid 4 examples, total effective rate is 86%, for treatment group 2, cures 15 examples, effective 8 examples, effective 5 examples, and invalid 1 example, total effective rate is 97%.Two groups of total effective rate comparing differences have statistical significance (P < 0.05).Observing over the course for the treatment of, all there is not obvious untoward reaction in two groups of patients.

Claims (8)

1. treat the externally applied ointment of osteopathia for one kind, it is characterized in that, it comprises the material of following weight portion: Radix Aconiti 10-30 part, Rhizoma Arisaematis 10-30 part, Herba Asari 10-30 part, Radix Angelicae Sinensis 10-30 part, Rhizoma Drynariae 10-20 part, Eupolyphaga Seu Steleophaga 10-20 part, Semen Momordicae 10-20 part, Pheretima 10-30 part, Bombyx Batryticatus 10-30 part, Semen Sinapis Albae 10-20 part, Pericarpium Citri Reticulatae Viride 10-30 part, Rhizoma Kaempferiae 10-30 part, Radix Dipsaci 10-20 part, Pollen Typhae 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Olibanum 10-30 part, Myrrha 10-30 part, Squama Manis 10-20 part and Radix Et Rhizoma Nardostachyos 10-30 part.
2. the externally applied ointment for the treatment of osteopathia according to claim 1, it is characterized in that, it comprises the material of following weight portion: Radix Aconiti 20 parts, Rhizoma Arisaematis 20 parts, Herba Asari 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Drynariae 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Semen Momordicae 15 parts, Pheretima 20 parts, Bombyx Batryticatus 20 parts, Semen Sinapis Albae 15 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Kaempferiae 20 parts, Radix Dipsaci 15 parts, Pollen Typhae 15 parts, Radix Paeoniae Rubra 15 parts, Radix Et Rhizoma Rhei 15 parts, Olibanum 20 parts, Myrrha 20 parts, Squama Manis 15 parts and Radix Et Rhizoma Nardostachyos 20 parts.
3. the externally applied ointment for the treatment of osteopathia according to claim 1 and 2, it is characterized in that, it also comprises the material of following weight portion: five leaf potatos 15 parts, Herba Fimbristylis dichotomae 10 parts, Herba Christiae Obcordatae 12 parts, Herba Briggsiae Chienii 15 parts, Indigo Naturalis 20 parts, Caulis Seu Folium Lespedezae Bicoloris 12 parts, Polygonum cynanchoides Hemsl. 15 parts, Herba lespedezae virgatae 10 parts, Flos Inulae 15 parts, Herba malachii aquatici 10 parts and Salvia japonica Thunb. 9 parts.
4. the externally applied ointment for the treatment of osteopathia according to claim 3, is characterized in that, described externally applied ointment can be ointment plaster or plaster liniment.
5. the purposes of compositions in the Chinese medicine of preparation treatment rheumatism muscle and joint disease, it is characterized in that, described compositions comprises the material of following weight portion: Radix Aconiti 10-30 part, Rhizoma Arisaematis 10-30 part, Herba Asari 10-30 part, Radix Angelicae Sinensis 10-30 part, Rhizoma Drynariae 10-20 part, Eupolyphaga Seu Steleophaga 10-20 part, Semen Momordicae 10-20 part, Pheretima 10-30 part, Bombyx Batryticatus 10-30 part, Semen Sinapis Albae 10-20 part, Pericarpium Citri Reticulatae Viride 10-30 part, Rhizoma Kaempferiae 10-30 part, Radix Dipsaci 10-20 part, Pollen Typhae 10-20 part, Radix Paeoniae Rubra 10-20 part, Radix Et Rhizoma Rhei 10-20 part, Olibanum 10-30 part, Myrrha 10-30 part, Squama Manis 10-20 part and Radix Et Rhizoma Nardostachyos 10-30 part.
6. purposes according to claim 5, it is characterized in that, described compositions comprises the material of following weight portion: Radix Aconiti 20 parts, Rhizoma Arisaematis 20 parts, Herba Asari 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Drynariae 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Semen Momordicae 15 parts, Pheretima 20 parts, Bombyx Batryticatus 20 parts, Semen Sinapis Albae 15 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Kaempferiae 20 parts, Radix Dipsaci 15 parts, Pollen Typhae 15 parts, Radix Paeoniae Rubra 15 parts, Radix Et Rhizoma Rhei 15 parts, Olibanum 20 parts, Myrrha 20 parts, Squama Manis 15 parts and Radix Et Rhizoma Nardostachyos 20 parts.
7. the purposes according to claim 5 or 6, it is characterized in that, described compositions also comprises the material of following weight portion: five leaf potatos 15 parts, Herba Fimbristylis dichotomae 10 parts, Herba Christiae Obcordatae 12 parts, Herba Briggsiae Chienii 15 parts, Indigo Naturalis 20 parts, Caulis Seu Folium Lespedezae Bicoloris 12 parts, Polygonum cynanchoides Hemsl. 15 parts, Herba lespedezae virgatae 10 parts, Flos Inulae 15 parts, Herba malachii aquatici 10 parts and Salvia japonica Thunb. 9 parts.
8. purposes according to claim 7, is characterized in that, described externally applied ointment can be ointment plaster or plaster liniment.
CN201510046365.2A 2015-01-29 2015-01-29 External use plaster used for treating bone diseases Pending CN104491645A (en)

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CN110141655A (en) * 2019-06-13 2019-08-20 费广生 A kind of plaster of the manufactured treatment spur and protrusion of lumber intervertebral disc of Chinese medicine

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CN104127618A (en) * 2014-08-17 2014-11-05 王勇 Plaster for treating heumatism
CN104147578A (en) * 2014-08-29 2014-11-19 韩世昌 Plaster for treating scapulohumeral periarthritis, and preparation method thereof

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