CN104474177A - Chinese medicinal preparation for treating attention deficiency hyperactivity disorder of children - Google Patents

Chinese medicinal preparation for treating attention deficiency hyperactivity disorder of children Download PDF

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CN104474177A
CN104474177A CN201410754709.0A CN201410754709A CN104474177A CN 104474177 A CN104474177 A CN 104474177A CN 201410754709 A CN201410754709 A CN 201410754709A CN 104474177 A CN104474177 A CN 104474177A
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radix
children
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medicine
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吴燕
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吴燕
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a Chinese medicinal preparation for treating attention deficit hyperactivity disorder (ADHD) of children. The Chinese medicinal preparation is prepared from the following Chinese medical herbs in parts by weight: 15 parts of prepared rhizome of adhesive rehmannia, 15 parts of milk peaches, 15 parts of immature fruits of medicine terminalia, 10 parts of borneol, 30 parts of grass leaf sweelflag rhizome, 30 parts of evening primrose seed oil, 15 parts of raw white paeony roots, 10 parts of fried liquorice root, 20 parts of anacyclus pyrethrum roots, 15 parts of tuber fleeceflower stems, 10 parts of himalayan four-o'clock roots, 5 parts of swertia petens burk., and 10 parts of herb of ternateleaf rabdosia. Clinical experiments show that the Chinese medical preparation has a significant effect on treating ADHD of children due to the combination of the selected suitable Chinese medical herbs at a proper ratio, and the Chinese medical preparation is safe and has no side or toxic effect.

Description

A kind of Chinese medicine preparation for hyperkinetic syndrome
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine preparation for hyperkinetic syndrome.
Background technology
Childhood hyperkinetic syndrome, being called for short childhood hyperkinetic syndrome, is a kind of behavior disorder of children disease, most from cradle i.e. aobvious symptom, as excited, sleep is poor, not easily forms timing defecation and be accustomed to, and school age is the most remarkable.The primary disease cause of disease it be unclear that, and it is generally acknowledged relevant with premature labor, difficult labour, cerebral trauma and some infectious disease, the factor such as poisoning, and has with Inheritance, congenital development and history of being born and necessarily contact; It belongs to traditional Chinese medical science liver-wind, become deaf, forgetful category, and all dirty in close relations with the heart, liver,spleen,kidney, part doctor starts with from heart spleen, start with from spleen kidney, research primary disease, but there is no satisfied Therapeutic Method so far.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine preparation for hyperkinetic syndrome, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to children's's hyperkinetic syndrome Rehabilitation, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine preparation for hyperkinetic syndrome, is prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 12 ~ 15 parts, milk Fructus Persicae 12 ~ 15 parts, FRUCTUS TERMINALIAE IMMATURUS 12 ~ 15 parts, Flos Mume brain 8 ~ l0 part, Rhizoma Acori Graminei 25 ~ 30 parts, Radix Oenotherae erythrosepalae oil 25 ~ 30 parts, Radix Paeoniae Alba 12 ~ 15 parts, Radix Glycyrrhizae Preparata 8 ~ 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 ~ 25 parts, Caulis Polygoni Multiflori 12 ~ 15 parts, Radix Mirabilis himalaicae 8 ~ 10 parts, children's tremble with fear medicine 0 ~ 5 part, Herba Rabdosiae Ternifoliae 0 ~ 10 part.
As preferably, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts.
As preferably, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts, Herba Rabdosiae Ternifoliae 10 parts.
As preferably, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts, children's tremble with fear medicine 5 parts.
As preferably, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts, children's tremble with fear medicine 5 parts, Herba Rabdosiae Ternifoliae 10 parts.
A kind of preparation method of the Chinese medicine preparation for hyperkinetic syndrome, comprise the steps: that (1) milk Fructus Persicae, FRUCTUS TERMINALIAE IMMATURUS, Rhizoma Acori Graminei, Radix Paeoniae Alba, dry root of Anacyclus pyrethrum(L.)DC., Caulis Polygoni Multiflori, Radix Mirabilis himalaicae, children's trembled with fear medicine, Herba Rabdosiae Ternifoliae puts into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Radix Rehmanniae Preparata, Radix Glycyrrhizae Preparata, Flos Mume brain, Radix Oenotherae erythrosepalae oil are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of hyperkinetic syndrome of the present invention.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Radix Rehmanniae Preparata [source] this product is the Preparation process product of Radix Rehmanniae.[nature and flavor] are sweet, tepor.[return through] returns liver, kidney channel.[function cures mainly] nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
The mature fruit that milk Fructus Persicae [source] is Zong Tong section plant Cocos nucifera L..[nature and flavor] secondary is damp and hot, sweet in the mouth.[function cures mainly] raw humidogene heat, atural beat in reinforcement, the fertile body of hemopoietic, the kidney warming replenishing essence, supplementing the brain improving eyesight, maintenance fetus, drives away helminth, and removing toxic substances is except epidemic disease.Cure mainly dry cold or black gallbladder matter disease, as cold paralysis, muscle muscle relaxation, psychosis, melancholia, dryness anemia body is thin, the empty poor or weak eyesight of oligospermia of suffering from a deficiency of the kidney, brain, frequent fetal movement, infested, the malicious epidemic disease of enteral be popular.
The dry young fruit that FRUCTUS TERMINALIAE IMMATURUS [source] is Combretum Racemosum plant Fructus Chebulae.[nature and flavor] secondary is dry cold, sour-puckery flavor.[function cures mainly] is raw dry raw cold, purification abnormal blood matter, dampness supplementing the brain, nootropics, relieving restlessness resolving depression, heat-clearing and toxic substances removing, dispelling wind for relieving itching, removing heat from blood black hair.Cure mainly humid or blood matter disease, as thousand property brains are empty, intelligence declines, and vexed fear, depression, leprosy, hemorrhoid, skin expectorant is itched, prematured white hair.
Flos Mume brain [source] medical material Ji Yuan: the native crystal compound of separating out in the resin for Spore density borneo camphor tree.[nature and flavor] are pungent; Bitter; Cool.[return through] heart; Lung meridian.[function cures mainly] has one's ideas straightened out refreshment; Heat radiation pain relieving; Improving eyesight removing nebula.Main apoplexy locked mouth; Calentura coma; Infantile convulsion expectorant fan; Deafness with qi stagnation; Conjunctivitis; Sore throat; Aphtha; Carbuncle; Hemorrhoid; Enterobiasis.
The rhizome of Rhizoma Acori Graminei [source] acorus gramineus araceae plant.[function cures mainly] removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Radix Oenotherae erythrosepalae oil [source] medical material Ji Yuan: be the fatty oil of the seeds such as onagraceae plant Radix Oenotherae erythrosepalae, Oenothera giazioviana Mich.[nature and flavor] bitter in the mouth; Micro-pungent; Micro-sweet; Property is put down.[function cures mainly] promoting blood circulation to remove obstruction in the collateral; Endogenous wind stopping suppressing the hyperactive liver; Detumescence sore.Main obstruction of qi in the chest and cardialgia; Apoplectic hemiplegia; Stirring-up of pathogenic wind in the interior resulting from deficiency; Children's moves more; Wind dampness rheumatic anesthesia pain; Stomachache is had loose bowels; Dysmenorrhea; Oral-anal-genital ulcer syndrome; Skin infection; Eczema.
Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Radix Glycyrrhizae Preparata [nature and flavor] is sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The root that dry root of Anacyclus pyrethrum(L.)DC. [source] is feverfew Rome Pyrethrum.Peppery and the numb tongue of [nature and flavor] acrid in the mouth.The strong muscle of [function cures mainly] cold relieving, opens retardance, removes excess in brain, warm-up tonifying YANG, and tonneau is through water, and controlling nocturnal emission with astringent drugs, wind-expelling pain-stopping, drying dampness to eliminate phlegm, nourishing is neural.Cure mainly raw property or open-minded liquid matter disease, as paralysis, facial paralysis, of flaccid muscles, paralysis, vibration, skin ulcer is sick, tongue weight, hyposexuality, and seminal fluid is not solid, and amenorrhea is not smooth, and headache toothache, excessive phlegm is coughed, neurasthenia.
The rattan that Caulis Polygoni Multiflori [source] is polygonum multiflorum thunb or leaf bine stem.[nature and flavor] sweet micro-hardship, flat.[function cures mainly] nourishes heart, and calms the nerves, and dredging collateral dispels the wind.Control insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
The root that Radix Mirabilis himalaicae [source] is Nyctaginaceae plant Radix Mirabilis himalaicae.[nature and flavor] are warm in nature, and sweet in the mouth is micro-pungent.[function cures mainly] invigorating spleen and kidney, diuretic.
Children's trembles with fear the herb of medicine [source] for the oblique stem Herba Swertiae bimaculatae of gentianaceae plant.[nature and flavor] are bitter; Pungent; Temperature.[function cures mainly] warming middle-JIAO to relieve pain; Spleen invigorating removing food stagnancy.Main children's's cold syndrome; Spasmodic colic; Infantile malnutrition; Dyspepsia.
Herba Rabdosiae Ternifoliae [source] Labiatae Rabdosia plant wheel blade Herba Rabdosiae glaucocalycis, with all herbal medicine.[nature and flavor] are bitter, micro-pungent, cool.[function cures mainly] clearing away heat-damp and promoting diuresis, removing toxic substances.For flu, bronchitis, tonsillitis, pharyngolaryngitis, toothache, enteritis, dysentery, icterohepatitis, acute nephritis, cystitis; Venom is controlled in external.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment hyperkinetic syndrome cure rate high and safe without toxic side effect.Between formula medical material, compatibility is rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, makes it reach medicine and removes to disease, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix Rehmanniae Preparata 15 grams, milk Fructus Persicae 15 grams, FRUCTUS TERMINALIAE IMMATURUS 15 grams, l0 gram, Flos Mume brain, Rhizoma Acori Graminei 30 grams, Radix Oenotherae erythrosepalae oil 30 grams, Radix Paeoniae Alba 15 grams, Radix Glycyrrhizae Preparata 10 grams, dry root of Anacyclus pyrethrum(L.)DC. 20 grams, Caulis Polygoni Multiflori 15 grams, Radix Mirabilis himalaicae 10 grams, children's tremble with fear medicine 5 grams, Herba Rabdosiae Ternifoliae 10 grams.Prepare according to the following steps: (1) milk Fructus Persicae, FRUCTUS TERMINALIAE IMMATURUS, Rhizoma Acori Graminei, Radix Paeoniae Alba, dry root of Anacyclus pyrethrum(L.)DC., Caulis Polygoni Multiflori, Radix Mirabilis himalaicae, children's trembled with fear medicine, Herba Rabdosiae Ternifoliae puts into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Radix Rehmanniae Preparata, Radix Glycyrrhizae Preparata, Flos Mume brain, Radix Oenotherae erythrosepalae oil are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of reflux esophagitis of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 30 days, be 1 course for the treatment of, take 3 courses for the treatment of continuously.
Embodiment 2
Take: Radix Rehmanniae Preparata 15 grams, milk Fructus Persicae 15 grams, FRUCTUS TERMINALIAE IMMATURUS 15 grams, l0 gram, Flos Mume brain, Rhizoma Acori Graminei 30 grams, Radix Oenotherae erythrosepalae oil 30 grams, Radix Paeoniae Alba 15 grams, Radix Glycyrrhizae Preparata 10 grams, dry root of Anacyclus pyrethrum(L.)DC. 20 grams, Caulis Polygoni Multiflori 15 grams, Radix Mirabilis himalaicae 10 grams, children's tremble with fear medicine 5 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.Embodiment 3
Take: Radix Rehmanniae Preparata 15 grams, milk Fructus Persicae 15 grams, FRUCTUS TERMINALIAE IMMATURUS 15 grams, l0 gram, Flos Mume brain, Rhizoma Acori Graminei 30 grams, Radix Oenotherae erythrosepalae oil 30 grams, Radix Paeoniae Alba 15 grams, Radix Glycyrrhizae Preparata 10 grams, dry root of Anacyclus pyrethrum(L.)DC. 20 grams, Caulis Polygoni Multiflori 15 grams, Radix Mirabilis himalaicae 10 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of hyperkinetic syndrome, selected the routine clinical observation of hyperkinetic syndrome patient 84 of institute's diagnosis and treatment since 2013, patient is divided into treatment group and matched group two groups at random, treatment group 42 example, matched group 42 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal.
Matched group list takes methylphenidate sheet 5mg/ time, observes after 2-3 days, if DeGrain, increases dosage gradually to 10-15mg.
Two groups was all 1 course for the treatment of with 1 month, 3 courses for the treatment of of continuous use.
3, efficacy determination:
The People's Republic of China's traditional Chinese medicine industry standard " TCM Pediatrics disease Standardization of diagnosis and curative effect " issued with reference to State Administration of Traditional Chinese Medicine is formulated.
(1) cure: upper class hour visual cognitive ability, emotion is more stable, and school grade reaches same age child level substantially, Neurological soft signs by positive shift be feminine gender.
(2) take a turn for the better: action reduces, and the time of sitting quietly is longer, and attention is slightly concentrated, and school grade rises to some extent, and Neurological soft signs part is turned out cloudy.
(3) do not heal: symptom and school grade are without significant change, and Neurological soft signs is without improvement.
4, result:
Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 30 examples, take a turn for the better 10 examples, and do not heal 2 examples, cure rate 71.4%, total effective rate 95.2%.
Cure 22 examples in matched group, take a turn for the better 11 examples, and do not heal 9 examples, cure rate 52.4%, total effective rate 78.6%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.

Claims (6)

1. the Chinese medicine preparation for hyperkinetic syndrome, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 12 ~ 15 parts, milk Fructus Persicae 12 ~ 15 parts, FRUCTUS TERMINALIAE IMMATURUS 12 ~ 15 parts, Flos Mume brain 8 ~ l0 part, Rhizoma Acori Graminei 25 ~ 30 parts, Radix Oenotherae erythrosepalae oil 25 ~ 30 parts, Radix Paeoniae Alba 12 ~ 15 parts, Radix Glycyrrhizae Preparata 8 ~ 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 ~ 25 parts, Caulis Polygoni Multiflori 12 ~ 15 parts, Radix Mirabilis himalaicae 8 ~ 10 parts, children's tremble with fear medicine 0 ~ 5 part, Herba Rabdosiae Ternifoliae 0 ~ 10 part.
2. a kind of Chinese medicine preparation for hyperkinetic syndrome according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts.
3. a kind of Chinese medicine preparation for hyperkinetic syndrome according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts, Herba Rabdosiae Ternifoliae 10 parts.
4. a kind of Chinese medicine preparation for hyperkinetic syndrome according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts, children's tremble with fear medicine 5 parts.
5. a kind of Chinese medicine preparation for hyperkinetic syndrome according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Rehmanniae Preparata 15 parts, milk Fructus Persicae 15 parts, FRUCTUS TERMINALIAE IMMATURUS 15 parts, Flos Mume brain l0 part, Rhizoma Acori Graminei 30 parts, Radix Oenotherae erythrosepalae oil 30 parts, Radix Paeoniae Alba 15 parts, Radix Glycyrrhizae Preparata 10 parts, dry root of Anacyclus pyrethrum(L.)DC. 20 parts, Caulis Polygoni Multiflori 15 parts, Radix Mirabilis himalaicae 10 parts, children's tremble with fear medicine 5 parts, Herba Rabdosiae Ternifoliae 10 parts.
6. the preparation method for the Chinese medicine preparation of hyperkinetic syndrome, it is characterized in that, comprise the steps: that (1) milk Fructus Persicae, FRUCTUS TERMINALIAE IMMATURUS, Rhizoma Acori Graminei, Radix Paeoniae Alba, dry root of Anacyclus pyrethrum(L.)DC., Caulis Polygoni Multiflori, Radix Mirabilis himalaicae, children's trembled with fear medicine, Herba Rabdosiae Ternifoliae puts into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Radix Rehmanniae Preparata, Radix Glycyrrhizae Preparata, Flos Mume brain, Radix Oenotherae erythrosepalae oil are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of reflux esophagitis of the present invention.
CN201410754709.0A 2014-12-11 2014-12-11 Chinese medicinal preparation for treating attention deficiency hyperactivity disorder of children Pending CN104474177A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104001022A (en) * 2014-05-22 2014-08-27 薛永梅 Traditional Chinese medicine for treating pediatric hyperkinetic syndrome and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104001022A (en) * 2014-05-22 2014-08-27 薛永梅 Traditional Chinese medicine for treating pediatric hyperkinetic syndrome and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李德仁: "《药品经营岗位知识与技能》", 31 January 2012, 中国医药科技出版社 *

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Application publication date: 20150401