CN104474084A - Traditional Chinese medicine composition for preparing patch for relaxing bowels - Google Patents
Traditional Chinese medicine composition for preparing patch for relaxing bowels Download PDFInfo
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- CN104474084A CN104474084A CN201410721486.8A CN201410721486A CN104474084A CN 104474084 A CN104474084 A CN 104474084A CN 201410721486 A CN201410721486 A CN 201410721486A CN 104474084 A CN104474084 A CN 104474084A
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- chinese medicine
- medicine composition
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- constipation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine composition for preparing a patch for relaxing bowels. The traditional Chinese medicine composition is a powder mixture prepared from the following medicinal materials in parts by weight: 16 parts of folium sennae, 30 parts of poria cocos, 10 parts of perilla frutescens, 30 parts of immature bitter orange, 20 parts of Chinese honeylocust fruit and 20 parts of mangnolia officinalis. A clinical experiment proves that the patch for relaxing bowels prepared by the traditional Chinese medicine composition can be safely and effectively applied to treatment of constipation.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine composition pasted for the preparation of relieving constipation.
Background technology
Constipation is a kind of common digestive tract disease, along with the change of dietary structure and the impact of psychiatric and social factor etc., has become the important disease affecting people's quality of life.Constipation can not only cause anorectal disorder, causes gastrointestinal dysfunction, more can increase the incidence rate of colon cancer, bring out the generation of Cardial or cerebral vascular diseases, and the metabolite such as the antibacterial produced during constipation, methane, diffuse into central nervous system, have a strong impact on brain function.Though it is not normal that constipation belongs to large intestine conduction function, very close with the relation of taste and kidney, constipation is independent disease, also sees the complication of clinical acute and chronic diseases.At present, conventional caccagogue has: 1. osmotic laxative, 2. osmotic laxative treatments, 3. emollient laxative, 4. suppository cathartic, 5. promote digestive tract power reinforcing medicine, 6. Chinese patent medicine etc., but long-term taking can cause drug dependence, fat soluble vitamin absorption is bad, abdominal distention sense of discomfort, the black change of large intestine even kidney damage.Chinese medicine acupoint application method treatment constipation is with a long history, and determined curative effect is economical and practical and untoward reaction is little, has unique advantage and significant curative effect.
Point application therapy sees the earliest " 52 Bingfang ", describes sinapism and sticks in Baihui acupoint, can treat venom; The Spring and Autumn and the Warring States Periods, " a Ling Shu Miraculous Pivot or Divine Axis passages through which vital energy circulates section " is recorded: " the musculature of meridian of Foot-YANG MING ... frequently muscle has cold, then suddenly draw cheek day and move mouth, has heat then muscular atonia; be unequal to folding and unfolding out-of-the-way, control with horse cream, its anxious person of cream; with Chinese liquor and osmanthus, to be coated with its slow person ... ", started the beginning of plaster treatment disease." Treatise on Febrile and Miscellaneous Disease " that the Eastern Han Dynasty Zhang Zhongjing is shown, the handbook of Prescription for Emergency of Jin Daige flood are all on the books to external treatment applying method, Song Yuan period, part doctor starts simply to inquire into outer treating method mechanism, as pointed out in " Shengji Zonglu ": " cream get its cream profit; with eliminating evil poison; the gas that all skin lies hidden and undeveloped, cream can disappear it, again can massage also." period of Ming and Qing; point application therapy progressively moves to maturity; and occur monograph; system finishing external treatment applying method, wherein the most famously shown " Li Yue Pianwen, Rhymed Discourse for Topical Remedies " by Wu Shangxian, not only the multiple outer treating method of itemized record; and according to basic theory of tcm; the mechanism of action of inner disease outer treat, system side are sent to the aspect such as medicine, concrete utilization and done detailed discussion, and theory of channels and collaterals of giving chapter and verse is chosen and sticked acupuncture point, for the Study and appliance of modern point application therapy is laid a good foundation.As wherein recorded treatment constipation method: Radix Et Rhizoma Rhei 30 g, Fructus Crotonis 15 g, Bulbus Allii Fistulosi 10, Moschus 1 g, grinds rear distillers yeast into powder and adjusts cream in right amount, be affixed on umbilical part, and treatment accumulation of heat type constipation curative effect is obvious.Fry Bulbus Allii Fistulosi to very hot with vinegar, press umbilicus portion with cloth bag, every day presses it, cures mainly YIN-cold and stagnates and yang deficiency constipation.Modern Ma Yuxia arranges forefathers' experience and writes " traditional Chinese medical science Medicinal Vesiculation Therapy is complete works of ", permeated by the stimulation of medicine, stimulate meridians conduction, impel a kind of outer treating method of QI-blood circulation, wherein record: Radix Kansui 3 g, Sal 3 g, Flos Caryophylli 1 g, the appropriate furnishing cream of Rhizoma Zingiberis Recens juice, sticks in Shenque, Zhigou, TIANSHU acupoint (ST25), constipation can be treated, constipation due to disorder of QI, constipation due to insufficiency, constipation due to accumulation of pathogenic cold.Fructus Crotonis 2g, Fructus Evodiae 6 g, Cortex Cinnamomi 3g, Rhizoma Zingiberis Recens juice is appropriate, and furnishing paste, sticks and treat with Shenque, tsu san li, QIHAI acupoint, defecate 12 ~ 24 h can under.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine composition pasted for the preparation of relieving constipation, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective treatment acute icterohepatitis.
In order to achieve the above object, the present invention is by the following technical solutions:
For the preparation of the Chinese medicine composition that relieving constipation is pasted, it is characterized in that, it refers to the raw medicinal material mixture of powders of following weight proportion: Folium Sennae 16 parts, 30 parts, Poria, Fructus Perillae Frutescentis 10 parts, Fructus Aurantii Immaturus 30 parts, Fructus Gleditsia 20 parts, Cortex Magnoliae Officinalis 20 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
This research case is all from during 2010-2013, and the patient of Yantai Traditional Chinese Medical-science's outpatient service and taste section lesion is totally 68 examples.Wherein, man 32 example, female 26 example, 60 ~ 70 years old 50 age example, 70 ~ 80 years old 18 example, the course of disease 2 ~ 15 years, one time 52 example of defecating for 3 ~ 5 days, 1 time 16 example of defecating for more than 1 week.Each defecation time 30 ~ 40 minutes, notably more than 1h.Constipation with dry stool, faces lavatory and exerts duty, often to dripping sweat.Many once or the catharsis medicine such as long-term taking rhubarb soda tablet, phenolphthalein, Folium Sennae or use glycerin, even help can defecation for hands.All get rid of intestinal organic disease through clysis with barium or colonoscopy, and get rid of the impact of the factors such as operation, medicine.
2, Therapeutic Method
The relieving constipation all giving the embodiment of the present invention 2 obtained is pasted, and every day one pastes, each subsides 3-5 hour.
3, criterion of therapeutical effect:
Clinical cure: defecation is normal, every day 1 time, each defecation time l0 ~ 20min, defecation is happy, without any discomfort, stops observation post administration 2 weeks, uncomfortable without any defecation.
Take a turn for the better: stool deliquescing legibility, 1 ~ 2 day 1 time, defecation time is less than 30min, does not feel tired out after an action of the bowels.
Effective: stool deliquescing can be separated, and 1 time on the every 2nd, defecation time 30 about min, has in 3 months repeatedly after drug withdrawal, need be interrupted consolidation of taking medicine.
Invalid: to have no any improvement or increase the weight of.
4, result
Clinical cure 42 example, accounts for 61.8%; Take a turn for the better 18 examples, accounts for 26.5%; Effective 8 examples, account for 11.7%; Total effective rate 100%.
Visible relieving constipation of the present invention is pasted and is used for the treatment of constipation determined curative effect, and drug safety is high, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take the pharmaceutical decocting piece of following weight proportion: Folium Sennae 16 parts, 30 parts, Poria, Fructus Perillae Frutescentis 10 parts, Fructus Aurantii Immaturus 30 parts, Fructus Gleditsia 20 parts, Cortex Magnoliae Officinalis 20 parts, mix after being ground into powder respectively, add lanoline 50 weight portion and vaseline 150 weight portion again, grind well, spread on backing layer according to the amount of 4 grams every part, cover anti-stick layer, sealing, obtain relieving constipation of the present invention and paste.
Embodiment 2
Take the pharmaceutical decocting piece of following weight proportion: Folium Sennae 16 parts, 30 parts, Poria, Fructus Perillae Frutescentis 10 parts, Fructus Aurantii Immaturus 30 parts, Fructus Gleditsia 20 parts, Cortex Magnoliae Officinalis 20 parts, add 8 times of water gagings, decoct 1.5 hours, filter, concentrated, drying, then add lanoline 10 weight portion and vaseline 30 weight portion, grind well, spread on backing layer according to the amount of 2 grams every part, cover anti-stick layer, sealing, obtain relieving constipation of the present invention and paste.
Claims (1)
1., for the preparation of the Chinese medicine composition that relieving constipation is pasted, it is characterized in that, it refers to the raw medicinal material mixture of powders of following weight proportion: Folium Sennae 16 parts, 30 parts, Poria, Fructus Perillae Frutescentis 10 parts, Fructus Aurantii Immaturus 30 parts, Fructus Gleditsia 20 parts, Cortex Magnoliae Officinalis 20 parts.
Priority Applications (1)
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CN201410721486.8A CN104474084A (en) | 2014-12-03 | 2014-12-03 | Traditional Chinese medicine composition for preparing patch for relaxing bowels |
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CN201410721486.8A CN104474084A (en) | 2014-12-03 | 2014-12-03 | Traditional Chinese medicine composition for preparing patch for relaxing bowels |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108721560A (en) * | 2018-09-03 | 2018-11-02 | 常州市中医医院 | Navel treatment for treating functional consitipation applies |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102743738A (en) * | 2012-07-27 | 2012-10-24 | 赵晓霞 | External use navel spreading sparadrap for treating gastrointestinal dysfunction |
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2014
- 2014-12-03 CN CN201410721486.8A patent/CN104474084A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102743738A (en) * | 2012-07-27 | 2012-10-24 | 赵晓霞 | External use navel spreading sparadrap for treating gastrointestinal dysfunction |
Non-Patent Citations (1)
Title |
---|
李瑛等: "中医外治疗法对功能性便秘的治疗概况", 《上海医药》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108721560A (en) * | 2018-09-03 | 2018-11-02 | 常州市中医医院 | Navel treatment for treating functional consitipation applies |
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Application publication date: 20150401 |