CN104435529A - Externally-applied preparation for treating traumatic injury and preparation method - Google Patents

Externally-applied preparation for treating traumatic injury and preparation method Download PDF

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CN104435529A
CN104435529A CN201410591812.8A CN201410591812A CN104435529A CN 104435529 A CN104435529 A CN 104435529A CN 201410591812 A CN201410591812 A CN 201410591812A CN 104435529 A CN104435529 A CN 104435529A
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radix
parts
schefflerae arboricolae
preparation
traumatic injury
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刘华
赵海红
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刘华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

Abstract

The invention discloses an externally-applied preparation for treating traumatic injury and a preparation method. The externally-applied preparation for treating traumatic injury is prepared from the following main raw materials in parts by weight: 3-5 parts of native copper, 4-6 parts of angelica sinensis, 5-10 parts of honeysuckle, 6-9 parts of radix clematidis, 3-6 parts of indigo naturalis, 4-9 parts of rhizoma drynariae, 1-3 parts of ophidian, 5-15 parts of pseudo-ginseng, 3-6 parts of radix cyathulae, 1-5 parts of flowers carthami, 4-10 parts of dioscorea nipponica and 2-8 parts of schefflera arboricola. The externally-applied preparation has a remarkable effect on treatment for traumatic injury, combines these medicines to enable the effects of the various medicines to generate a synergistic effect, and has the effects of activating blood circulation, dispersing stasis and dredging collaterals, and reuniting bones, relieving pain and strengthening muscles and bones, thus the externally-applied preparation can effectively treat traumatic injury. The externally-applied preparation disclosed by the invention mainly uses locally common medicinal materials and has a low price, thus reducing the economical burden of the patient.

Description

The externally applied formulation for the treatment of traumatic injury and preparation method
Technical field
The invention belongs to traditional Chinese medicine field, especially a kind of externally applied formulation and preparation method for the treatment of traumatic injury.
Background technology
Traumatic injury comprises weapons, tumbling down, hits, sprain and contusion, stab, abrade, athletic injury, sprain, there are pain, swelling, hemorrhage or fracture, dislocation etc. in injury more.At this mainly based on soft tissue injury.
In daily life for some people seemingly homely food, people is because of the soft tissue injury caused by reasons such as falling, beat, touch, knock, with swelling, pain for main manifestations for general reference.After traumatic injury occurs some people, diagnosis and treatment of being eager, often use medicine fumigation and wash method, in fact sometimes doing very easily like this, things turn out contrary to one's wishes.Not only be of no curative effect, and the state of an illness can be more and more serious.How does traumatic injury subside a swelling fast? if only damaged soft tissue, time suitable, adopt Chinese herbal medicine fumigation and wash method, be of value to and alleviate disease.Traditional Chinese medical science fumigation and wash method medicine used is many to be formed by Chinese herbal medicine compatibilities such as Radix Angelicae Sinensis, Radix Notoginseng, Flos Carthami, the Radix Paeoniae Alba, Radix Achyranthis Bidentatae, Myrrha, Olibanum, Oletum Trogopteroris, has effect of blood circulation promoting and blood stasis dispelling, alleviating pain and detumescence.But be also sometimes superficial charm.But if traumatic injury just occurs, just wash with medicine and control, affected part blood vessel will aggravate expansion, and oozing of blood, edema also can increase the weight of at once thereupon, not only can cause soft tissue adhesion and local miopragia, but also very easily strengthen pain.Therefore, after damaging, cold compress should be adopted immediately, affected part vasoconstriction can be made like this and reduce hemorrhage, edema and pain.After the three or four day of damage, adopt the external application of pseudo-ginseng blood-circulation-invigovating cream to wash again, be used in conjunction several days, just can reach the effect of blood circulation promoting and blood stasis dispelling, alleviating pain and detumescence.
The Chinese patent literature of Authorization Notice No. CN 101804158 B (application number 201010152062.6) discloses a kind of ointment for injuries, it is characterized in that it is made up of the crude drug of following weight proportioning: Os Draconis: 30g, Cortex Albiziae: 35g, Rhizoma Pleiones Yunnanensis: 30g, Radix Dipsaci: 35g, female ground beetle: 27g, Rhizoma Dioscoreae Septemlobae: 35g, Pyritum: 12g, Radix Berchemiae Giraldianae: 30g, Radix Cyathulae: 25g, Bos taurus domesticus Gmelin: 37g, Pyritum: 35g, Radix Polygalae: 30g, Rhizoma Drynariae: 30g, Sanguis Draxonis: 25g, Borneolum Syntheticum: 25g, Aerugo 20g, Camphora 45g.The Chinese patent literature of Authorization Notice No. CN 101455790 B (application number 200710198535.4) discloses a kind of nine traumatic injury pills, and its formula is as follows: Radix Celastri Orbiculati 140-160 gram; Radix campsis 140-160 gram; Radix Alangii 55-75 gram; Root of Radix Clematidis 70-90 gram; Radix Achyranthis 55-75 gram; Root of Cortex Acanthopanacis Radicis 90-110 gram; Root of Caulis Spatholobi 170-190 gram; Root of Herba Verbenae Offcinalis 130-150 gram; Rhizoma Imperatae 80-100 gram.
In a word, Chinese medicine achieves good curative effect in treatment primary disease, but also there are some problems: clinically to activating blood circulation to dissipate blood stasis and dredge the collateral, symplectic bone pain relieving bone and muscle strengthening is desirable not enough, has much room for improvement to improving the misery that traumatic injury brings.
Summary of the invention
The object of this invention is to provide a kind of preparation method simple, easy to use, the externally applied formulation of the treatment traumatic injury that the cure rate that is easy to carry is high and preparation method.Having invigorates blood circulation cures the wound, blood stasis dispelling stimulates the menstrual flow, the effect relieved the pain.And adopt Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The externally applied formulation for the treatment of traumatic injury, takes off the primary raw material stating weight proportion and is prepared from: Pyritum 3-5 part, Radix Angelicae Sinensis 4-6 part, Flos Lonicerae 5-10 part, Radix Clematidis 6-9 part, Indigo Naturalis 3-6 part, Rhizoma Drynariae 4-9 part, ophidia 1-3 part, Radix Notoginseng 5-15 part, Radix Cyathulae 3-6 part, Flos Carthami 1-5 part, Rhizoma Dioscoreae Nipponicae 4-10 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 2-8 part.
The externally applied formulation for the treatment of traumatic injury, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Pyritum 3.5-4.5 part, Radix Angelicae Sinensis 4.5-5.5 part, Flos Lonicerae 6-9 part, Radix Clematidis 5-8 part, Indigo Naturalis 4-5 part, Rhizoma Drynariae 5-8 part, ophidia 1.5-2.5 part, Radix Notoginseng 8-13 part, Radix Cyathulae 4-5 part, Flos Carthami 2-4 part, Rhizoma Dioscoreae Nipponicae 6-8 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 4-6 part.
The externally applied formulation for the treatment of traumatic injury, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Pyritum 4 parts, Radix Angelicae Sinensis 5 parts, Flos Lonicerae 8 parts, Radix Clematidis 7 parts, Indigo Naturalis 4.5 parts, Rhizoma Drynariae 6 parts, ophidia 2 parts, Radix Notoginseng 10 parts, Radix Cyathulae 4.5 parts, 3 parts, Flos Carthami, Rhizoma Dioscoreae Nipponicae 4 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 5 parts.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment traumatic injury.
The preparation method of the externally applied formulation for the treatment of traumatic injury, step is as follows:
(1) Pyritum is broken into the block that length, width and height are all 1-3 centimetre, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 80-120 mesh sieve;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 4-8 minute, be placed in the crock of with closure, add white vinegar, stir with large ferrum spoon, fully soak after 15-25 hour, be placed in the upper little fire of the iron plate of burning heat and smoke 20-40 minute, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 10-20 time, gained mixing medicamental pulverata packs and get final product.
Above-mentioned preparation method, Pyritum is broken into the block (preferably Pyritum being broken into the block that length, width and height are all 2 centimetres) that length, width and height are all 1.5-2.5 centimetre by step (1).
Above-mentioned preparation method, step (1) smalls crosses 90-110 mesh sieve (preferred, smalls crosses 100 mesh sieves).
Above-mentioned preparation method, step (2) high temperature sterilize 5-7 minute (preferred high temperature sterilize 6 minutes).
Above-mentioned preparation method, step (2) white vinegar fully soaks 18-23 hour (preferably fully soaking 20 hours with white vinegar).
Above-mentioned preparation method, step (2) is placed in the upper little fire of the iron plate of burning heat and smokes 25-35 minute (be preferably placed in the upper little fire of the iron plate of burning heat and smoke 30 minutes).
Above-mentioned preparation method, the consumption of step (2) white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 3-7 doubly (preferred, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 4-6 doubly, more preferably good, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 5 times).
Using method: for making the present invention reach optimum efficiency, gained mixing medicamental pulverata, gets 20g at every turn, mixes thoroughly with Ovum Gallus domesticus album, spread upon affected part, and every two days once, is for 5 times a course for the treatment of.
These drug regimens, to treatment traumatic injury Be very effective, make each efficacy of drugs produce synergism, have activating blood circulation to dissipate blood stasis and dredge the collateral, the effect of symplectic bone pain relieving bone and muscle strengthening, thus effectively can treat traumatic injury by this externally applied formulation.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Pyritum: pungent is flat.Dissipating blood stasis, synthetism, pain relieving.For treating swelling and pain by traumatic injury, injured bone.Enter the loose clothes of ball more; External is ground into powder and is dressed.Nature steel all has anti-true mattress effect in various degree to the multiple pathogenic epiphyte for examination, especially stronger to thread true mattress effects such as Gypsum Fibrosum sample hair moss bacterium, aspergillus terreuses.Gypsum Fibrosum sample hair moss mattress is inoculated into guinea pig back, causes guinea pig experimental tinea model, then be coated with Pyritum decoct outward at lesions position, find that nature steel also has certain therapeutic effect to guinea pig experimental tinea.
Radix Angelicae Sinensis: Radix Angelicae Sinensis another name is dryly returned, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, contain that Radix Angelicae Sinensis, Radix Angelicae Sinensis are bent, Radix Angelicae Gigatis, it is herbaceos perennial, and its root can be used as medicine, and is one of the most frequently used Chinese medicine.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.For blood deficiency, shallow complexion, dizzy cardiopalmus; Blood deficiency, or have the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea concurrently; The pain such as deficient cold type stomachache, angina pectoris, rheumatic arthralgia, traumatic injury card; Dryness of the intestine constipation; Chronic cough is panted.
Flos Lonicerae: Flos Lonicerae, having another name called Radix Ophiopogonis " Flos Lonicerae " one comes from Compendium of Material Medica, owing to opening as white at the beginning of Flos Lonicerae, after transfer yellow to, hence obtain one's name Flos Lonicerae.Medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or is with the flower just opened.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Radix Clematidis: be ranunculaceae plant, Radix Clematidis: pungent, salty, temperature.Return urinary bladder channel.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Indigo Naturalis: salty, cold, return Liver Channel.There is heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, effect of arresting convulsion.Cure mainly: epidemic febrile disease intenseness of heat, macule, spit blood, spit blood, pharyngalgia aphtha, pediatric epilepsy scared, skin ulcer swells, erysipelas, snake bite and insect sting.
Rhizoma Drynariae: Rhizoma Drynariae, another name: precipice Rhizoma Zingiberis Recens, rock connect Rhizoma Zingiberis Recens, delevay drynaria, the broken benefit of meat, the broken benefit of stone, flying apsaras Mus, Niu Feilong, sudden wind, moth grass.The kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Ophidia: Zaocys, is commonly called as Zaocys, zaocys dhumnades, for Colubridae Zaocys belongs to the larger nonpoisonous snake of the bodily form, dispels the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Radix Notoginseng: Radix Notoginseng is Umbellales Araliaceae Panax herbaceos perennial, and root stock is short, and fleshy tap root is cylindrical, palmately compound leaf, umbel top is raw, brightly yellowish green; Calyx cup-shaped.Hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, fall and flutter blood stasis, traumatic hemorrhage, carbuncle pain.
Radix Cyathulae: Radix Cyathulae has another name called Radix Achyranthis Bidentatae, turns knee joint, the full Radix Achyranthis Bidentatae in sky, all NIUJIAO etc.Dispel the wind, dampness removing, stimulates the menstrual flow, and invigorates blood circulation.Dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea, lump in the abdomen.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.
Flos Carthami: another name: red indigo plant flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, dry tubular flower, orange red, floral tube is carefully narrow, and tip 5 splits, and sliver is narrow linear, and flower pesticide is yellow, and be unified into pipe, exceed outside sliver, its central authorities have stigma to expose.The special fragrance of tool, mildly bitter flavor.To spend, length of a film, color are scarlet, the soft person of matter is good.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect.Have blood circulation promoting and blood stasis dispelling, wet dissipation goes the effect swollen,
Rhizoma Dioscoreae Nipponicae: Rhizoma Dioscoreae Nipponicae: another name Dioscorea nipponica Mak. Ningpo Yam Rhizome, Rhizoma Dioscoreae Nipponicae, Dioscorea nipponica bone, ground joist, Rhizoma Smilacis Bockii, chicken bone, mountain Radix Dichroae, Radix Dichroae, parthenocissus, tip of a whip dish.Flavor efficacy: bitter is flat.Return liver, lung meridian.Function relaxing muscles and tendons to promote blood circulation, timid wind pain relieving, relieving cough and asthma, timid expectorant.Be applicable to lumbago and skelalgia, muscles and bones numbness, traumatic injury, lumbar sprain and QI divergeny, cough pant.
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae): be root or the stem and leaf of Araliaceae Schefflera plant schefflera arboricola.Composition: containing sickleleaf celery alcohol in schefflera arboricola; Also containing (E)-β-farnesene, poriferasterol.2 Triterpene saponins: 3-O-[a-L-rhamnopyranosyl-(1a)-beta d glucopyranosiduronic acid base] oleanolic acid 28-O-β-D-pyranglucoside are contained, 3-O-[a-L-arabopyranose base-(1a)-beta d glucopyranosiduronic acid base] oleanolic acid 28-O-β-D-pyranglucoside in leaf and stem.Cell kassinin kinin element class is also had, trans-Semen Maydis purine, benzyladenine in leaf.The property of medicine: pungent, sweet, micro-hardship, temperature.Function cures mainly: wind-expelling pain-stopping, promoting blood circulation and detumescence.Cure mainly rheumatic arthralgia, headache, toothache, epigastric pain, dysmenorrhea, puerperal abdonimal pain, treating swelling and pain by traumatic injury, fracture, skin ulcer swells.
Traditional Chinese medicine external preparation of the present invention meets the principle that disease treatment debated by Chinese medicine.Selected materials is all Chinese medicine material, without any side effects; This prescription meets Chinese medicine principle and traumatic injury patient body and mind feature completely, under the prerequisite of general principle, can have different prescription according to different crowd, and function is different.Medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 treats the externally applied formulation of traumatic injury, takes off the primary raw material stating weight proportion (every part of 20g) and is prepared from: Pyritum 3 parts, Radix Angelicae Sinensis 4 parts, Flos Lonicerae 5 parts, Radix Clematidis 6 parts, Indigo Naturalis 3 parts, Rhizoma Drynariae 4 parts, ophidia 1 part, Radix Notoginseng 5 parts, Radix Cyathulae 3 parts, 1 part, Flos Carthami, Rhizoma Dioscoreae Nipponicae 4 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 2 parts.
The preparation method of the externally applied formulation for the treatment of traumatic injury:
(1) Pyritum is broken into the block that length, width and height are all 1 centimetre, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 80 mesh sieves;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 4 minutes, be placed in the crock of with closure, add white vinegar, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 3 times, stir with large ferrum spoon, abundant immersion is after 15 hours, be placed in the upper little fire of the iron plate of burning heat and smoke 20 minutes, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 10 times, gained mixing medicamental pulverata packs and get final product.
Embodiment 2 treats the externally applied formulation of traumatic injury, takes off the primary raw material stating weight proportion (every part of 10g) and is prepared from: Pyritum 5 parts, Radix Angelicae Sinensis 6 parts, Flos Lonicerae 10 parts, Radix Clematidis 9 parts, Indigo Naturalis 6 parts, Rhizoma Drynariae 9 parts, ophidia 3 parts, Radix Notoginseng 15 parts, Radix Cyathulae 6 parts, 5 parts, Flos Carthami, Rhizoma Dioscoreae Nipponicae 10 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 8 parts.
The preparation method of the externally applied formulation for the treatment of traumatic injury:
(1) Pyritum is broken into the block that length, width and height are all 3 centimetres, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 120 mesh sieves;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 8 minutes, be placed in the crock of with closure, add white vinegar, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 7 times, stir with large ferrum spoon, abundant immersion is after 25 hours, be placed in the upper little fire of the iron plate of burning heat and smoke 40 minutes, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 20 times, gained mixing medicamental pulverata packs and get final product.
Typical case one Wu XX, man, 35 years old, Jinan, Shandong Province personage, the athletic meeting once held company causes left lower limb ligament injury because quantity of motion is excessive, afterwards when every rainy cloudy day, very serious of knee joint and patella position swelling pain, walk when the severity of aching all very difficult, when fine day, knee joint also has landing sense, can have snap, under the advice repeatedly of layman time movable, comprehensive inspection of having gone to hospital to do, doctor says that MRI has patella major injury.Under the advice of doctor, carried out traumatic injury operation, also feel when just having finished hands very well, malaise symptoms all disappears, and household is for he is glad.So get back to again company's working, once elevator breaks down suddenly, can only walking go downstairs, after unfortunately going back home, patella position occurs again where serious pain is also with redness, learn externally applied formulation of the present invention friend, just have the attitude of having a try in arms and buy 2 courses for the treatment of
After using a course for the treatment of of the present embodiment 2 gained externally applied formulation, patient's gonalgia alleviates, after continuing to use a course for the treatment of of embodiment 2 gained externally applied formulation, the gonalgia disappears, patient sees that having taken a favorable turn and bought 2 courses for the treatment of uses, 4 courses for the treatment of use rear malaise symptoms and all disappear, without recurrence after drug withdrawal.
Embodiment 3 treats the externally applied formulation of traumatic injury, takes off the primary raw material stating weight proportion (every part of 10g) and is prepared from: Pyritum 3.5 parts, Radix Angelicae Sinensis 4.5 parts, Flos Lonicerae 6 parts, Radix Clematidis 5 parts, Indigo Naturalis 4 parts, Rhizoma Drynariae 5 parts, ophidia 1.5 parts, Radix Notoginseng 8 parts, Radix Cyathulae 4 parts, 2 parts, Flos Carthami, Rhizoma Dioscoreae Nipponicae 6 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 4 parts.
The preparation method of the externally applied formulation for the treatment of traumatic injury:
(1) Pyritum is broken into the block that length, width and height are all 1.5 centimetres, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 90 mesh sieves;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 5 minutes, be placed in the crock of with closure, add white vinegar, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 4 times, stir with large ferrum spoon, abundant immersion is after 18 hours, be placed in the upper little fire of the iron plate of burning heat and smoke 25 minutes, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 13 times, gained mixing medicamental pulverata packs and get final product.
Embodiment 4 treats the externally applied formulation of traumatic injury, takes off the primary raw material stating weight proportion (every part of 10g) and is prepared from: Pyritum 4.5 parts, Radix Angelicae Sinensis 5.5 parts, Flos Lonicerae 9 parts, Radix Clematidis 8 parts, Indigo Naturalis 5 parts, Rhizoma Drynariae 8 parts, ophidia 2.5 parts, Radix Notoginseng 13 parts, Radix Cyathulae 5 parts, 4 parts, Flos Carthami, Rhizoma Dioscoreae Nipponicae 8 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6 parts.
The preparation method of the externally applied formulation for the treatment of traumatic injury:
(1) Pyritum is broken into the block that length, width and height are all 2.5 centimetres, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 110 mesh sieves;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 7 minutes, be placed in the crock of with closure, add white vinegar, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 6 times, stir with large ferrum spoon, abundant immersion is after 23 hours, be placed in the upper little fire of the iron plate of burning heat and smoke 35 minutes, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 18 times, gained mixing medicamental pulverata packs and get final product.
Typical case two Zou XX, female, 37 years old, people from Qingdao, peasant, do manual work in other places throughout the year, several years ago when manual labour, injured by a crashing object knee joint position by stone, so went examination in hospital not have very serious problem also how not to be present to the mind at that time, soon, Ms Zhang work in building site stair climbing time, suddenly oneself gonalgia is felt once, do not take notice of and continue to work, after going home evening at a glance, knee has slight swelling, Jiao Lock, pain is more and more serious, the husband of Ms Zhang thinks the pain that the reason of tiring out very much causes, buy on plaster just to Mrs Zou, be in after rest a period of time, Mrs Zou leaves the bed walking, how to get to road direction leans to one side to find oneself, just be terribly frightened at that time, the hospital that loses no time checks, doctor says slight amyotrophy phenomenon, MRI has traumatic injury sign.
After using a course for the treatment of of embodiment 4 gained externally applied formulation, check, patient's readme: after using a course for the treatment of, my sensory symptoms is obviously alleviated, and arthralgia obviously reduces, swelling disappears, Mrs Zou has initiatively bought again and has continued 5 courses for the treatment of to use, after using 3 courses for the treatment of of embodiment 4 gained externally applied formulation, arthralgia stops, and malaise symptoms disappears completely, do after continuing again to employ 2 courses for the treatment of and consolidate, without recurrence after drug withdrawal.
Embodiment 5 treats externally applied formulation and the preparation method of traumatic injury, takes off the primary raw material stating weight proportion (every part of 10g) and is prepared from; Pyritum 4 parts, Radix Angelicae Sinensis 5 parts, Flos Lonicerae 8 parts, Radix Clematidis 7 parts, Indigo Naturalis 4.5 parts, Rhizoma Drynariae 6 parts, ophidia 2 parts, Radix Notoginseng 10 parts, Radix Cyathulae 4.5 parts, 3 parts, Flos Carthami, Rhizoma Dioscoreae Nipponicae 4 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 5 parts.
The preparation method of the externally applied formulation for the treatment of traumatic injury:
(1) Pyritum is broken into the block that length, width and height are all 2 centimetres, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 100 mesh sieves;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 6 minutes, be placed in the crock of with closure, add white vinegar, the consumption of white vinegar be Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 5 times, stir with large ferrum spoon, abundant immersion is after 20 hours, be placed in the upper little fire of the iron plate of burning heat and smoke 30 minutes, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 15 times, gained mixing medicamental pulverata packs and get final product.
Test example 1 2011 years Decembers in January, 1 2014, have 400 patients and use.Inclusion criteria: the patient being diagnosed as traumatic injury, 400 patients are divided into two large groups at random, experimental group and matched group, experimental group uses embodiment 5 products obtained therefrom, and other medicine (conventional medication such as tablet for relieving rigidity of muscles and promoting blood circulation, promoting blood circulation and stopping pain soup, Radix Notoginseng capsule, the raw muscle of pain relieving) is taken/used to matched group.Curative effect situation criterion: cure: the tract pain sense of traumatic injury disappears, and can take vigorous exercise, clap MRI and show patella normally, energy and muscle power obviously strengthen; Effective: this disappearance of traumatic injury pain sensillary base, can be suitable take vigorous exercise, energy and muscle power strengthen to some extent; Invalid: malaise symptoms is unchanged, clap MRI and show traumatic injury.
Table 1: two groups of Clinical efficacy comparisons [example (%)]
Group case load clinical cure enabledisable cure rate total effective rate
Group Case load Clinical cure Effectively Invalid Cure rate Total effective rate
Experimental group 200 192 6 2 96% 99%
Matched group 200 140 20 40 70% 80%
Result: two groups of Clinical efficacy comparisons, matched group cure rate is 70%, and total effective rate is 80%; Experimental group cure rate is 96%, and total effective rate is that 99%, two groups of Clinical efficacy comparisons show that experimental group curative effect is better than matched group.Prove through clinical trial, use externally applied formulation of the present invention, the symptom of pain that traumatic injury brings, swelling can be treated fast and effectively, comparatively comprehensively can treat traumatic injury, reaching the object of reduction of patient misery, conditioning patient body, is a kind of externally applied formulation for the treatment of traumatic injury safely and effectively.
Table 2: before and after two groups of treatments, Clinical symptom and sign evaluation situation compares
Observation item time stable disease situation (%) pain alleviates situation (people)
Note: in upper table, stable disease percent and pain alleviate situation data and all take the mean.
Result: before and after two groups of treatments, Clinical symptom and sign evaluation situation compares, and after treatment, two groups of patients, 2 curative effect indexs are treated all to some extent, and experimental group therapeutic effect is obviously better than matched group.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat the externally applied formulation of traumatic injury, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Pyritum 3-5 part, Radix Angelicae Sinensis 4-6 part, Flos Lonicerae 5-10 part, Radix Clematidis 6-9 part, Indigo Naturalis 3-6 part, Rhizoma Drynariae 4-9 part, ophidia 1-3 part, Radix Notoginseng 5-15 part, Radix Cyathulae 3-6 part, Flos Carthami 1-5 part, Rhizoma Dioscoreae Nipponicae 4-10 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 2-8 part.
2. the externally applied formulation for the treatment of traumatic injury according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Pyritum 3.5-4.5 part, Radix Angelicae Sinensis 4.5-5.5 part, Flos Lonicerae 6-9 part, Radix Clematidis 5-8 part, Indigo Naturalis 4-5 part, Rhizoma Drynariae 5-8 part, ophidia 1.5-2.5 part, Radix Notoginseng 8-13 part, Radix Cyathulae 4-5 part, Flos Carthami 2-4 part, Rhizoma Dioscoreae Nipponicae 6-8 part, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 4-6 part.
3. the externally applied formulation for the treatment of traumatic injury according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Pyritum 4 parts, Radix Angelicae Sinensis 5 parts, Flos Lonicerae 8 parts, Radix Clematidis 7 parts, Indigo Naturalis 4.5 parts, Rhizoma Drynariae 6 parts, ophidia 2 parts, Radix Notoginseng 10 parts, Radix Cyathulae 4.5 parts, 3 parts, Flos Carthami, Rhizoma Dioscoreae Nipponicae 4 parts, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 5 parts.
4. the preparation method of the externally applied formulation of the treatment traumatic injury according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Pyritum is broken into the block that length, width and height are all 1-3 centimetre, put into suitable container, it is crisp to be placed in forging on smokeless stove fire, cools and grinds to form smalls, crosses 80-120 mesh sieve;
(2) Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) are cleaned, drain away the water, high temperature sterilize 4-8 minute, be placed in the crock of with closure, add white vinegar, stir with large ferrum spoon, fully soak after 15-25 hour, be placed in the upper little fire of the iron plate of burning heat and smoke 20-40 minute, cool and be ground into smalls and sieve;
(3) add Indigo Naturalis after step (1) being mixed with (2) gained smalls, fully rock 10-20 time, gained mixing medicamental pulverata packs and get final product.
5. preparation method according to claim 4, is characterized in that: Pyritum is broken into the block (preferably Pyritum being broken into the block that length, width and height are all 2 centimetres) that length, width and height are all 1.5-2.5 centimetre by step (1).
6. preparation method according to claim 4, is characterized in that: step (1) smalls crosses 90-110 mesh sieve (preferred, smalls crosses 100 mesh sieves).
7. preparation method according to claim 4, is characterized in that: step (2) high temperature sterilize 5-7 minute (preferred high temperature sterilize 6 minutes).
8. preparation method according to claim 4, is characterized in that: step (2) white vinegar fully soaks 18-23 hour (preferably fully soaking 20 hours with white vinegar).
9. preparation method according to claim 4, is characterized in that: step (2) is placed in the upper little fire of the iron plate of burning heat and smokes 25-35 minute (be preferably placed in the upper little fire of the iron plate of burning heat and smoke 30 minutes).
10. preparation method according to claim 4, it is characterized in that: the consumption of step (2) white vinegar is Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, the 3-7 of Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight is doubly (preferred, the consumption of white vinegar is Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, the 4-6 of Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight doubly, more preferably good, the consumption of white vinegar is Radix Angelicae Sinensis, Flos Lonicerae, Radix Clematidis, Rhizoma Drynariae, ophidia, Radix Notoginseng, Radix Cyathulae, Flos Carthami, Rhizoma Dioscoreae Nipponicae and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) gross weight 5 times).
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