CN104435127A - Traditional Chinese medicine for treating lithiasis in urinary system - Google Patents
Traditional Chinese medicine for treating lithiasis in urinary system Download PDFInfo
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- CN104435127A CN104435127A CN201410725550.XA CN201410725550A CN104435127A CN 104435127 A CN104435127 A CN 104435127A CN 201410725550 A CN201410725550 A CN 201410725550A CN 104435127 A CN104435127 A CN 104435127A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention relates to a traditional Chinese medicine for treating lithiasis in a urinary system. The traditional Chinese medicine disclosed by the invention is prepared from the following medicinal raw materials in parts by weight: 12 parts of lygodiaceae lygodium microstachyum, 9 parts of dichondra repens, 5 parts of juglands mandshurica kernels, 19 parts of glechoma biondiana, 11 parts of walnut kernel, 36 parts of kazinoki broussonetia, and 8 parts of Siberian elm leaf. Clinical experiments prove that the traditional Chinese medicine disclosed by the invention is capable of treating lithiasis in the urinary system safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of urinary system calculus.
Background technology
Urinary system calculus refers to the calculus betiding urinary system.Also known as urinary calculus.Comprise the calculus of kidney, ureter, bladder and urethra.The generation development of urinary calculus and nutriture have substantial connection, based on vegetable protein in poor and backward national food, lack phosphate in urine, easily vesical calculus occur, and children's is particularly common, and developed country's common adult's calcic renal calculus.The theory that urinary calculi is formed is a lot, as become nuclear doctrine, theory of matrix initiation, crystallization mortifier theory, the Forming Mechanism of whole urinary calculi also can be described without any theory.The salt forming calculus crystal in urine is over-saturation state, and suppressing the existence of crystal formation material deficiency and nuclear matrix in urine, is the lithogenous principal element of shape.Doctor trained in Western medicine is mainly through more oral medicines, and as treatment or operative treatments such as phenothiazine drug, allopurinol, orthophosphate, but the elimination of residual calculus and recurrence are the clinical main bugbears faced.Urinary system calculus belongs to the category of " sand Stranguria ", " stranguria caused by urinary stone ", " stranguria with blood " and " lumbago " in Chinese medicine, and therefore exploitation effectively can promote that calculus is discharged the cheap and Chinese medicine that side effect is little and had important practical significance to control urinary calculus.According to the traditional Chinese medical science " treating different diseases with the same therapeutic principle ", urinary system calculus is classified as " sand Stranguria ", " stranguria caused by urinary stone ", " stranguria with blood " and " lumbago "; Again according to the theory of the traditional Chinese medical science " treating the same disease with different methods ", respectively from invigorating the spleen and benefiting QI, benefiting vital QI and blood, blood circulation promoting and blood stasis dispelling, warming the kidney to invigorate YANG, the aspects such as nourishing kidney yin set about treating urinary system, the Chinese medicine compound that exploitation therapeutic effect is good, relapse rate is little.
Medical material present Research involved in the present invention is as follows:
The herb that Lygodium microstachyum Desv. [source] is Lygodiaceae plant Lygodium microstachyum Desv. or spore.Herb summer, autumn gather, and spore is gathered autumn, dry or using fresh herb.[habitats distribution] is distributed in the ground such as Zhejiang, Fujian, Taiwan, Guangdong, Guangxi, Hainan, Yunnan.[nature and flavor] micro-hardship; Sweet; Cool.[return through] urinary bladder channel.[function cures mainly] clearing away heat-damp and promoting diuresis.Main urinary system infection; Urinary system calculus; Burn and scald.[usage and dosage] takes orally: decoct soup, 9-15g.External: appropriate, grinds into powder deposited; Or fresh goods is smash deposited.[extracts] " China's book on Chinese herbal medicine "
The herb that Herba Dichondrae Repentis [another name] pocket grass, Boiled small dumplings with pork careless, JINSUOSHI, Herba Dichodrae, little Herba Calthae Membranaceae, the big grass of spiral shell, little Hydrocotyle vulgaris L. [source] are dicotyledon scammonia section plant Herba Dichodrae.The whole year can adopt at any time, using fresh herb or clean dry.[nature and flavor] toil; Cool.[function cures mainly] heat clearing away; Dampness removing; Removing toxic substances.Main jaundice; Dysentery; Sand Stranguria; Nebulousurine; Edema; Furuncle swelling toxin; Traumatic injury; Venom.[usage and dosage] takes orally: decoct soup, 6-15g, fresh goods 30-60g.External: appropriate, smashes deposited.[extracts] " China's book on Chinese herbal medicine "
The kernel that Juglans mandshurica kernel [source] is juglandaceae plant Juglans mandshurica.Gather during fruit maturation in autumn, removing outer peel, endocarp (shell), get core, dry.[nature and flavor] are sweet; Warm in nature.[function cures mainly] is astringed the lung and is relievingd asthma; Warming and recuperating the kidney-YANG; Loosening bowel to relieve constipation.Main cough and asthma due to lung deficiency; Lumbago due to renal deficiency; Seminal emission sexual impotence; Constipation.[usage and dosage] takes orally: decoct soup, 3-9g; Or enter ball, loose.[extracts] " China's book on Chinese herbal medicine "
Herba Glechoma biondiana [another name] Radix seu Folium Gaultheriae Forrestii, Herba Glechomae, HUOXUEDAN, JIANZHONGXIAO [source] are the Labiatae bar thing herb that disappears of cunning thoroughly in vain.[nature and flavor] acrid in the mouth; Warm in nature.[function cures mainly] expelling wind and activating blood circulation; Eliminating damp, detoxifying.Main air pain of dampness syndrome; Traumatic injury; Lung abscess; Jaundice; Acute nephritis; Calculus of urethra; Mumps.[usage and dosage] takes orally: decoct soup, 15-60g.[extracts] " China's book on Chinese herbal medicine "
The kernel that semen juglandis [another name] Rana limnocharis, the Semen Juglandis stalks of rice, wheat, etc., Semen Juglandis, Semen Juglandis [source] are juglandaceae plant Semen Juglandis.9-10 middle of the month, turn yellow until outer peel, most of fruit top ftractureed or minority comes off time, hit fruit down.Fructus Canarii can use ethephon 200-300 times immersion 0.5min, picks up, puts 2-3d on ventilation concrete floor, or results front 3 weeks is sprayed on really face with ethephon 200-500 times liquid and accelerates the ripening.Drupe washes, and pours in bleaching powder, wait turn yellow white time pick up, rinse, dry in the sun, with 40-50 DEG C of oven dry.By placement parallel to the ground for the bad mold joint of Semen Juglandis, hit out nucleocapsid, take out kernel, dry.All there is cultivation various places, [habitats distribution] China north and south.[nature and flavor] are sweet; Puckery; Warm in nature.[return through] kidney; Liver; Lung meridian.[function cures mainly] tonifying the kidney to consolidate the essence; Warming the lung Dingchuan; Loosening bowel to relieve constipation.Main lumbago flaccidity of the lower limbs; Frequent micturition; The enuresis; Sexual impotence; Seminal emission; Chronic cough dyspnea with rapid and short breath; Dryness of the intestine constipation; Stranguria caused by urinary stone and skin infection scrofula.[usage and dosage] takes orally: decoct soup, 9-15g; Single chews clothes; 10-30g; Or enter ball, loose.External: grind into powder smash deposited.[extracts] " China's book on Chinese herbal medicine "
Paddy skin rattan [another name] rattan Portugal coils, Clausena lansium (Lour.) Skeels rattan [source] this product is moraceae plants paddy skin rattan Herb or root, root bark.The 4-11 month excavates, and cleans, and section, dries or using fresh herb.[nature and flavor] are micro-sweet; Property is put down.[function cures mainly] clearing away heat and promoting diuresis; Promoting blood circulation and detumescence.Main cough due to lung-heat; Stranguria dne to urolithiasis; Jaundice; Tumbling down damages.[usage and dosage] takes orally: decoct soup, 30-60g.External: smash deposited.[extracts] " China's book on Chinese herbal medicine "
Folium ulmi pumilae [another name] elm leaf [source] this product is the leaf of Ulmaceae elm.Summer, picking leaves in autumn, using fresh herb or dry.[nature and flavor] are sweet; Property is put down.[function cures mainly] clearing away heat and promoting diuresis; Calm the nerves; Expelling phlegm for arresting cough.Main edema; Dysuria; Stranguria caused by urinary stone; Turbid urine; Insomnia; Summer-heat is stranded vexed; Abundant expectoration is coughed; Wine (looking into skin) nose.[usage and dosage] takes orally: decoct soup, 5-10g; Or enter ball, loose.External: appropriate, decocts washing.[extracts] " China's book on Chinese herbal medicine "
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of urinary system calculus, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing urinary system calculus.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of urinary system calculus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Lygodium microstachyum Desv. 12 parts, Herba Dichondrae Repentis 9 parts, 5 parts, Juglans mandshurica kernel, Herba Glechoma biondiana 19 parts, semen juglandis 11 parts, 36 parts, paddy skin rattan, Folium ulmi pumilae 8 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor's in JIUYUE, 2011 collects urinary system calculus patient 98 example of outpatient clinic altogether between in April ,-2013, all meet urinary system calculus diagnostic criteria.Two groups of Genders, age basic documents compare in table 1.
A table 1 liang group sex and age compares
Compare P by the visible two groups of Sex, Ages of table 1 and be all greater than 0.05, namely two groups of Sex, Age there was no significant differences, have comparability.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.2 weeks courses for the treatment of.
The oral lithagogue infusion of matched group (Nanjing pharmaceutcal corporation, Ltd of Tongrentang), uses according to its description).2 weeks courses for the treatment of.
All patients treatments period great quantity of water drinking, every day more than amount of drinking water 3000mL, night, sleep before and get up urinate after all to drink water, urine volume remains on more than 2000mL every day.According to the analysis of stone composition and urinary fractions, adjustment diet composition, general principle is low albumen homovitamin, eats Herba Spinaciae, Lentinus Edodes, Herba Astragali Sinici etc. less containing the many food of oxalic acid.
2.2 observation index
Treatments period observes weekly clinical symptoms (hematuria, frequent micturition and urgent micturition), sign (kidney district tenderness, percussion pain) and picture of the tongue, a pulse condition.Recurrence is observed after one month.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Criterion of therapeutical effect is drafted with reference to " Chinese medical disease clinical efficacy standard ":
Recovery from illness: calculus all excretes, B ultrasonic, CT and X-ray examination show that calculus shade all disappears, symptom, sign disappear, and tracing study 1 month is without clinical symptoms.
Effective: it is comparatively large or see that part calculus disappears that calculus moves down distance, or calculus volume obviously reduces, and renal pelvis hydrops disappears, the disappearance of symptom, sign;
Effective: symptom, sign obviously alleviate, and calculus obviously moves down, smaller volume, or multiple calculus quantity reduces or partial disappearance;
Invalid: though symptom, sign are without improving or being improved, calculus position, volume are without significant change person.
Effectively total=recovery from illness+effective+effectively.
3.2 therapeutic outcome
Two groups of clinical total effects results contrast are in table 2.
Table 2 liang group Clinical efficacy comparison
It is high and not easily recur that visible the present invention is used for the treatment of urinary system calculus cure rate, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Lygodium microstachyum Desv. 12 grams, Herba Dichondrae Repentis 9 grams, 5 grams, Juglans mandshurica kernel, Herba Glechoma biondiana 19 grams, semen juglandis 11 grams, 36 grams, paddy skin rattan, Folium ulmi pumilae 8 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of urinary system calculus.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Lygodium microstachyum Desv. 12 grams, Herba Dichondrae Repentis 9 grams, 5 grams, Juglans mandshurica kernel, Herba Glechoma biondiana 19 grams, semen juglandis 11 grams, 36 grams, paddy skin rattan, Folium ulmi pumilae 8 grams; Add 10 times of water gagings, decoct 2 hours, filter: filtering residue adds 8 times of water gagings, decocts 1.5 hours, filter; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of urinary system calculus.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 3
Take: Lygodium microstachyum Desv. 12 grams, Herba Dichondrae Repentis 9 grams, 5 grams, Juglans mandshurica kernel, Herba Glechoma biondiana 19 grams, semen juglandis 11 grams, 36 grams, paddy skin rattan, Folium ulmi pumilae 8 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of urinary system calculus.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of urinary system calculus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Lygodium microstachyum Desv. 12 parts, Herba Dichondrae Repentis 9 parts, 5 parts, Juglans mandshurica kernel, Herba Glechoma biondiana 19 parts, semen juglandis 11 parts, 36 parts, paddy skin rattan, Folium ulmi pumilae 8 parts.
2. a kind of Chinese medicine being used for the treatment of urinary system calculus as claimed in claim 1, it is characterized in that, its preparation method is: take: Lygodium microstachyum Desv. 12 parts, Herba Dichondrae Repentis 9 parts, 5 parts, Juglans mandshurica kernel, Herba Glechoma biondiana 19 parts, semen juglandis 11 parts, 36 parts, paddy skin rattan, Folium ulmi pumilae 8 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of urinary system calculus as claimed in claim 1, it is characterized in that, its preparation method is: take: Lygodium microstachyum Desv. 12 parts, Herba Dichondrae Repentis 9 parts, 5 parts, Juglans mandshurica kernel, Herba Glechoma biondiana 19 parts, semen juglandis 11 parts, 36 parts, paddy skin rattan, Folium ulmi pumilae 8 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of urinary system calculus as claimed in claim 1, it is characterized in that, its preparation method is: take: Lygodium microstachyum Desv. 12 parts, Herba Dichondrae Repentis 9 parts, 5 parts, Juglans mandshurica kernel, Herba Glechoma biondiana 19 parts, semen juglandis 11 parts, 36 parts, paddy skin rattan, Folium ulmi pumilae 8 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410725550.XA CN104435127A (en) | 2014-11-27 | 2014-11-27 | Traditional Chinese medicine for treating lithiasis in urinary system |
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| CN201410725550.XA CN104435127A (en) | 2014-11-27 | 2014-11-27 | Traditional Chinese medicine for treating lithiasis in urinary system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104922509A (en) * | 2015-05-29 | 2015-09-23 | 陈英娣 | Traditional Chinese medicine for treating lithiasis in urinary system |
| CN105232625A (en) * | 2015-11-25 | 2016-01-13 | 复旦大学附属中山医院 | Traditional Chinese capsule treating urinary calculi and preparation method thereof |
-
2014
- 2014-11-27 CN CN201410725550.XA patent/CN104435127A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 国家中医药管理局局《中华本草》编委会: "《中华本草》", 31 December 1999, 上海科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104922509A (en) * | 2015-05-29 | 2015-09-23 | 陈英娣 | Traditional Chinese medicine for treating lithiasis in urinary system |
| CN105232625A (en) * | 2015-11-25 | 2016-01-13 | 复旦大学附属中山医院 | Traditional Chinese capsule treating urinary calculi and preparation method thereof |
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