CN104398911A - Medicine oral liquid for treating metrorrhagia and metrostaxis - Google Patents

Medicine oral liquid for treating metrorrhagia and metrostaxis Download PDF

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CN104398911A
CN104398911A CN201410673317.1A CN201410673317A CN104398911A CN 104398911 A CN104398911 A CN 104398911A CN 201410673317 A CN201410673317 A CN 201410673317A CN 104398911 A CN104398911 A CN 104398911A
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metrorrhagia
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李坤
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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Abstract

The invention discloses a medicine oral liquid for treating metrorrhagia and metrostaxis. The medicine oral liquid is prepared from the following raw material medicines in parts by weight: 5-10 parts of lindley eupatorium, 10-20 parts of immature bitter oranges, 5-10 parts of astragalus membranaceus, 10-15 parts of lancea tibetica, 15-25 parts of lily, 5-10 parts of oroxylum indicum, 10-25 parts of honeysuckle, 5-10 parts of asarum, 5-10 parts of pseudo-ginseng, 15-25 parts of poris cocos, 3-8 parts of euphorbia lunulata, 10-15 parts of semen coicis, 10-20 parts of carthamus tinctorius and 10-20 parts of liquorice. The preparation method comprises the following steps: mixing the raw material medicines, adding water to boil for 2-3 hours, filtering to obtain a filtrate, and concentrating the filtrate till the relative density is 1.20 (measured at 30 DEG C) to obtain the medicine oral liquid. The medicine oral liquid is orally taken for twice a day and 20-40 ml each time. The medicine oral liquid disclosed by the invention has the outstanding advantages that the curative effect is fast, a small amount of medicines are used, and the treatment course is short.

Description

A kind of medicine oral liquid for the treatment of metrorrhagia
Technical field
The present invention relates to a kind of take Chinese herbal medicine as the medicine oral liquid of the treatment metrorrhagia of raw material.
Background technology
Metrorrhagia is the commonly encountered diseases of gynecological, frequently-occurring disease, and women's (after menolipsis) vagina not between menstrual period or between menstrual period is bled profusely suddenly, or the continuous person of dripping hematochezia, be called " metrorrhagia ", if menostaxis reaches more than two weeks persons, metrorrhagia category should be belonged to, be called " metrorrhagia " or " menometrorrhagia ".General unexpected hemorrhage, the oncoming force is anxious, and many crying of blood volume is collapsed; Dripping hematochezia, the oncoming force is delayed, and what blood volume was few cries Lou; Though collapse different from the bleeding leaked, its pathogeny is consistent, and often in disease progression mutually transforms, as metrorrhagia with the passing of time, QI and blood consumption wound, becomes leakage; Leakage of a specified duration is more than, and patient's condition day enters, and also can become to collapse, so usually metrorrhagia claiming clinically, metrorrhagia is more than, blood and qi deficiency, the trip of husband's QI and blood, follows meridians outward, interior flourish internal organs, and trauma is appointed in punching, can not keep within bounds menses, be with passages through which vital energy circulates entanglement, under large blood is sudden and violent, as collapsing of mountain, all lost greatly by QI and blood, taste first damage.Primary disease is more common, and Chang Yin collapses and replaces with leakage, and cause and effect is concerned with, and causes the touching difficulty of pathological changes more, becomes the difficult serious symptom of gynecological.The main pathogenesis of metrorrhagia is the impairment of chong and ren channels, can not restrict menses, causes the common cause of the debility of CHONG and REN meridians to have: 1, to suffer from a deficiency of the kidney: congenital deficiency of kidney-QI, maiden's kidney qi is childish and tender, climacteric kidney qi degradation, or early marriage fecund, sexual life is book not, damage kidney qi, if consumption hinders essence and blood, then kidney yin is deficient, yin asthenia generating intrinsic heat, accumulation of heat in CHONG and REN meridians, the absurd row of forcing blood, so that under when menses are non-, then become metrorrhagia.2, insufficiency of the spleen: to be worried too much, improper diet and overtiredness, damage temper; Sinking of QI of middle-JIAO, the debility of CHONG and REN meridians, blood loses and has under one's command, under time non-, then becomes metrorrhagia.3, heat in blood: innate excess of YANG in the body or feelings gas unsuccessful, pathogenic fire derived from stagnation of liver-QI, or catching pathogenic heat, or the pungent supporing yang product of surfeit, contain in burning hot, and thermal burn punching is appointed, and chases after the absurd row of blood, under time non-, then becomes metrorrhagia.4, blood stasis: mood internal injury, qi depression to blood stasis, or the heresy that impression is cold, hot, cold coagulation or heat are burnt and are caused the stasis of blood, stagnation of blood stasis in CHONG and REN meridians, escape of blood from meridians, under time non-, then become metrorrhagia.
Now, the clinical onset rate of metrorrhagia is more and more higher, does not but have a kind of effective method to cure: conventional gynaecologic metrorrhagia medication curative effect is slow, and the time is long, poor to the therapeutic effect of metrorrhagia, and medication is difficult to cure for four or five days; If perform an operation, not only spend high, patient is painful, and DeGrain, have a strong impact on the physical and mental health of patient, bring many miseries and inconvenience to the work of patient, study and daily life.
Summary of the invention
For above-mentioned prior art, slow to metrorrhagia therapeutical effect for solving existing medicine, the problems such as weak effect, the invention provides the medicine oral liquid of a kind of high curative effect, speed healing gynaecologic metrorrhagia, have the advantage such as reliable in quality, safe quick-acting.
The present invention is achieved by the following technical solutions:
Treating a medicine oral liquid for metrorrhagia, is be made up of the crude drug of following weight portion: Herba Eupatorii Lindleyani 5 ~ 10 parts, Fructus Aurantii Immaturus 10 ~ 20 parts, the Radix Astragali 5 ~ 10 parts, Fructus Lanceae tibeticae 10 ~ 15 parts, Bulbus Lilii 15 ~ 25 parts, Semen Oroxyli 5 ~ 10 parts, Flos Lonicerae 10 ~ 25 parts, Herba Asari 5 ~ 10 parts, Radix Notoginseng 5 ~ 10 parts, Fu 15 ~ 25 parts, Herba euphorbiae lunulatae 3 ~ 8 parts, Semen Coicis 10 ~ 15 parts, 10 ~ 20 parts, Flos Carthami, 10 ~ 20 parts, Radix Glycyrrhizae.
Preferably, be made up of the crude drug of following weight portion: Herba Eupatorii Lindleyani 8 parts, Fructus Aurantii Immaturus 15 parts, the Radix Astragali 8 parts, Fructus Lanceae tibeticae 13, Bulbus Lilii 20 parts, Semen Oroxyli 8 parts, Flos Lonicerae 18 parts, Herba Asari 8 parts, Radix Notoginseng 8 parts, Fu 20 parts, Herba euphorbiae lunulatae 5 parts, Semen Coicis 12 parts, 15 parts, Flos Carthami, 15 parts, Radix Glycyrrhizae.
The preparation method of the medicine oral liquid of described treatment metrorrhagia is: get each crude drug, and mixing, decoct with water 2 ~ 3 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
Medicine oral liquid of the present invention cures mainly metrorrhagia, and using method is oral, one day twice, each 20 ~ 40ml.
Medicine oral liquid of the present invention is by traditional Chinese medical science pharmacology, prescription opinion prescription, in conjunction with the pure Chinese medicinal formulae of ancient times, modern clinic scientific research composition, has the outstanding advantages such as curative effect is fast, medication is few, time short (namely curing in one week) clinically.Pharmacology, toxicology test prove that medicine oral liquid of the present invention is without any side reaction, cure rate and effective percentage high, be one square medicine safely and efficiently, blank filled up in clinical treatment metrorrhagia (menorrhagia).
Detailed description of the invention
Below in conjunction with embodiment and case, the present invention is further illustrated:
Embodiment 1 prepares the medicine oral liquid for the treatment of metrorrhagia
Get Herba Eupatorii Lindleyani 8 grams, Fructus Aurantii Immaturus 15 grams, the Radix Astragali 8 grams, Fructus Lanceae tibeticae 13, Bulbus Lilii 20 grams, Semen Oroxyli 8 grams, Flos Lonicerae 18 grams, Herba Asari 8 grams, Radix Notoginseng 8 grams, Fu 20 grams, Herba euphorbiae lunulatae 5 grams, Semen Coicis 12 grams, 15 grams, Flos Carthami, 15 grams, Radix Glycyrrhizae, mixing, decocts with water 2 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
Embodiment 2 prepares the medicine oral liquid for the treatment of metrorrhagia
Get Herba Eupatorii Lindleyani 5 grams, Fructus Aurantii Immaturus 10 grams, the Radix Astragali 10 grams, Fructus Lanceae tibeticae 15 grams, Bulbus Lilii 15 grams, Semen Oroxyli 5 grams, Flos Lonicerae 25 grams, Herba Asari 10 grams, Radix Notoginseng 5 grams, Fu 15 grams, Herba euphorbiae lunulatae 8 grams, Semen Coicis 15 grams, 10 grams, Flos Carthami, 10 grams, Radix Glycyrrhizae, mixing, decocts with water 3 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
Embodiment 3 prepares the medicine oral liquid for the treatment of metrorrhagia
Get Herba Eupatorii Lindleyani 10 grams, Fructus Aurantii Immaturus 20 grams, the Radix Astragali 5 grams, Fructus Lanceae tibeticae 10 grams, Bulbus Lilii 25 grams, Semen Oroxyli 10 grams, Flos Lonicerae 10 grams, Herba Asari 5 grams, Radix Notoginseng 10 grams, Fu 25 grams, Herba euphorbiae lunulatae 3 grams, Semen Coicis 10 grams, 20 grams, Flos Carthami, 20 grams, Radix Glycyrrhizae, mixing, decocts with water 2 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
Embodiment 4 prepares the medicine oral liquid for the treatment of metrorrhagia
Get Herba Eupatorii Lindleyani 6 grams, Fructus Aurantii Immaturus 18 grams, the Radix Astragali 6 grams, Fructus Lanceae tibeticae 14 grams, Bulbus Lilii 18 grams, Semen Oroxyli 9 grams, Flos Lonicerae 15 grams, Herba Asari 9 grams, Radix Notoginseng 6 grams, Fu 18 grams, Herba euphorbiae lunulatae 5 grams, Semen Coicis 11 grams, 18 grams, Flos Carthami, 12 grams, Radix Glycyrrhizae, mixing, decocts with water 3 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
Embodiment 5 prepares the medicine oral liquid for the treatment of metrorrhagia
Get Herba Eupatorii Lindleyani 9 grams, Fructus Aurantii Immaturus 13 grams, the Radix Astragali 9 grams, Fructus Lanceae tibeticae 12 grams, Bulbus Lilii 22 grams, Semen Oroxyli 6 grams, Flos Lonicerae 20 grams, Herba Asari 6 grams, Radix Notoginseng 9 grams, Fu 22 grams, Herba euphorbiae lunulatae 8 grams, Semen Coicis 14 grams, 13 grams, Flos Carthami, 17 grams, Radix Glycyrrhizae, mixing, decocts with water 2 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
Clinical data
Metrorrhagia patient 84 example, 19 ~ 50 years old age.Metrorrhagia diagnostic criteria: women's heavy vaginal bleeding non-menstrual period or lasting hematochezia, dripping urine endlessly, dark red or the blackout of menses, accompanies stasis of blood block, and companion's dizziness and tinnitus, soreness of waist pain, lazy speech of breathing hard, body is tired, poor appetite, complexion are yellowish or facial slight edema, white and thin fur, deep pulse are thin and delicate etc.
Therapeutic modality: take medicine oral liquid prepared by embodiment 1, oral, one day twice, each 30ml.Take observe the curative effect after a week.
Curative effect determinate standard:
Cure: after hemorrhage control, continuous 3 menstrual cycle, menstrual period, blood volume all recover normal, and felling ailments oneself disappears completely, recover normally ovulate, luteal phase > 12 days.
Effective: after hemorrhage control, menstrual cycle, blood volume recover normal substantially, but menstrual period still longer (7 ~ 10 days), and felling ailments oneself disappears substantially.
Take a turn for the better: menstrual period shorten, oligemia, menstrual cycle makes moderate progress, part felling ailments oneself be improved significantly.
Invalid: menstrual cycle, menstrual period, blood volume, felling ailments oneself all without improvement, must transform other treatment into.
Therapeutic outcome: in 84 routine patients, cures 45 examples, effective 28 examples, and take a turn for the better 7 examples, invalid 4 examples.

Claims (3)

1. treat a medicine oral liquid for metrorrhagia, it is characterized in that: be made up of the crude drug of following weight portion: Herba Eupatorii Lindleyani 3 ~ 7 parts, Fructus Aurantii Immaturus 7 ~ 12 parts, the Radix Astragali 5 ~ 8 parts, Fructus Lanceae tibeticae 8 ~ 12 parts, Bulbus Lilii 4 ~ 8 parts, Semen Oroxyli 4 ~ 8 parts, Flos Lonicerae 4 ~ 7 parts, Herba Asari 6 ~ 10 parts, Radix Notoginseng 7 ~ 12 parts, 5 ~ 10 parts, Poria, Herba euphorbiae lunulatae 8 ~ 15 parts, Semen Coicis 8 ~ 15 parts, 5 ~ 10 parts, Flos Carthami, 3 ~ 8 parts, Radix Glycyrrhizae.
2. a kind of medicine oral liquid for the treatment of metrorrhagia according to claim 1, is characterized in that: be made up of the crude drug of following weight portion: Herba Eupatorii Lindleyani 8 parts, Fructus Aurantii Immaturus 15 parts, the Radix Astragali 8 parts, Fructus Lanceae tibeticae 13, Bulbus Lilii 20 parts, Semen Oroxyli 8 parts, Flos Lonicerae 18 parts, Herba Asari 8 parts, Radix Notoginseng 8 parts, Fu 20 parts, Herba euphorbiae lunulatae 5 parts, Semen Coicis 12 parts, 15 parts, Flos Carthami, 15 parts, Radix Glycyrrhizae.
3. a kind of preparation method for the treatment of the medicine oral liquid of metrorrhagia according to claim 1 and 2, is characterized in that: get each crude drug, mixing, decoct with water 2 ~ 3 hours, filter to get filtrate, it is 1.20 (30 DEG C of surveys) that filtrate is concentrated into relative density, to obtain final product.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110121072A (en) * 2010-04-30 2011-11-07 주식회사 엔케이바이오 Development of anti-cancer composition against skin cancer, lung cancer, uterine cancer and stomach cancer by proliferation inhibitory activity against cancer cell line in human
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Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110121072A (en) * 2010-04-30 2011-11-07 주식회사 엔케이바이오 Development of anti-cancer composition against skin cancer, lung cancer, uterine cancer and stomach cancer by proliferation inhibitory activity against cancer cell line in human
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