CN104396947B - A kind of aqua type pesticidal preparations taking ionic liquid as cosolvent and prepare - Google Patents
A kind of aqua type pesticidal preparations taking ionic liquid as cosolvent and prepare Download PDFInfo
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- CN104396947B CN104396947B CN201410543454.3A CN201410543454A CN104396947B CN 104396947 B CN104396947 B CN 104396947B CN 201410543454 A CN201410543454 A CN 201410543454A CN 104396947 B CN104396947 B CN 104396947B
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
The invention belongs to agriculture field, providing a kind of aqua type pesticidal preparations taking ionic liquid as cosolvent and prepare, is by ionic liquid, water, the mixture that pesticide original medicine forms, wherein ionic liquid content is 10%-30%, pesticide original medicine content is 1%-30%, and all the other are supplied by water.The present invention uses ionic liquid as cosolvent, the problem of organic solvent pollution in pesticidal preparations can be solved to a great extent, because ionic liquid burning-point is high, not volatile, and the most important thing is physicochemical property especially surface-active and the molecular polarity by regulating the group of anion and cationic moiety can regulate ionic liquid, these character directly can affect it as the solvability of cosolvent to former medicine, these all make ionic liquid can prepare water-based pesticides formulation as cosolvent, thus can greatly reduce or substitute completely the use of the organic solvent in conventional dosage forms.
Description
Technical field
The invention belongs to agriculture field, being specifically related to a kind of take ionic liquid as the pesticidal preparations of cosolvent.
Background technology
In recent years, the kind of China's formulations of pesticide presents increasing trend, but still there is the problem of unreasonable structure, old formulation (as missible oil) remains the main body of pesticide market, and a large amount of organic solvent in missible oil is (as toluene, dimethylbenzene, mixed benzene etc.) use, the development prospect of this formulation is caused anxiety, therefore find organic solvent substitute or the transformation of missible oil being carried out environmental friendliness become a problem important and urgently to be resolved hurrily.And ionic liquid can address this problem just to a great extent, because ionic liquid burning-point is high, not volatile, and the most important thing is physicochemical property especially surface-active and the molecular polarity by regulating the group of anion and cationic moiety can regulate ionic liquid, these character directly can affect it as the solvability of cosolvent to former medicine, these all make ionic liquid can prepare water-based pesticides formulation as cosolvent, thus can greatly reduce or substitute completely the use of the organic solvent in conventional dosage forms.
Summary of the invention
The invention provides the aqua type pesticidal preparations that a kind of novel ion liquid is prepared as cosolvent.
Problem to be solved by this invention there are provided the aqua type pesticidal preparations that a kind of novel ion liquid is prepared as cosolvent, thus reduces the use of the organic solvent in Traditional Agricultural pharmaceutically dosage form.
The technical scheme realizing above-mentioned purpose of the present invention is:
Take ionic liquid as an aqua type pesticidal preparations for cosolvent preparation, be by ionic liquid, water, the mixture that pesticide original medicine forms, wherein ionic liquid content is 10% ~ 30%, and pesticide original medicine content is 1% ~ 30%, and all the other are supplied by water.
Wherein, described pesticide original medicine is lythidathion (active constituent content 98%), a kind of former medicine in cyromazine (active constituent content 98%) and pyrethrin (active constituent content 70%).
As one of optimal technical scheme of the present invention, described aqua type pesticidal preparations intermediate ion content liquid is 20% ~ 30%, and pesticide original medicine content is 11.5% ~ 30%, and all the other are supplied by water; Described pesticide original medicine is the former medicine of lythidathion.
Lythidathion is organic phosphor nematocide, main with dry control nematode, aphid etc.Former medicine is light brown grease.Solvability (20 DEG C) in water is 9.85mg/L, is usually made as 10% granule or 10% emulsifiable concentrate.
As another optimal technical scheme of the present invention, described aqua type pesticidal preparations intermediate ion content liquid is 20% ~ 30%, and pesticide original medicine content is 3% ~ 12%, and all the other are supplied by water; Described pesticide original medicine is pyrethrosin primary medicine.
Pyrethrin is soluble in dimethylbenzene, toluene, ethyl acetate, ethanol, acetone, dimethyl formamide, is insoluble in water.Usually missible oil, microemulsion or emulsion is made as.
As the third optimal technical scheme of the present invention, wherein ionic liquid content is 20% ~ 30%, and pesticide original medicine content is 1%-10%, and all the other are supplied by water; Described pesticide original medicine is the former medicine of cyromazine.
The former medicine of cyromazine is white or faint yellow solid, and the solvability in water is 11000mg/L (PH7.5), is slightly dissolved in methyl alcohol and ethanol.Usually 75% wetting powder, 50% wetting powder, 10% aqua or 50% soluble powder is made as.
Wherein, described ionic liquid is 1-octyl group-3-methylimidazole Pfansteihl salt or 1-butyl-3-methylimidazole L-PROLINE salt.
Aqua type pesticidal preparations of the present invention, adopts following steps preparation:
Take ionic liquid and water in proportion, mixing, after stirring 1 minute to formation clear solution, add pesticide original medicine, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains aqua type pesticidal preparations.
Beneficial effect of the present invention is:
Ionic liquid can solve the problem of organic solvent pollution in pesticidal preparations just to a great extent as cosolvent, because ionic liquid burning-point is high, not volatile, and the most important thing is physicochemical property especially surface-active and the molecular polarity by regulating the group of anion and cationic moiety can regulate ionic liquid, these character directly can affect it as the solvability of cosolvent to former medicine, these all make ionic liquid can prepare water-based pesticides formulation as cosolvent, thus can greatly reduce or substitute completely the use of the organic solvent in conventional dosage forms.
Embodiment
Following examples further illustrate content of the present invention, but should not be construed as limitation of the present invention.
In embodiment, lythidathion former medicine purchased from American Mo Sai technology company content 98%, the former medicine of cyromazine is purchased from Jiangsu Institute of Econones Co., Ltd.'s content 98%, and pyrethrosin primary medicine is purchased from Yunnan Chuan Sen Industrial Co., Ltd. content 70%.
Embodiment 1:
Taking 2.5g1-octyl group-3-methylimidazole Pfansteihl salt adds in 7.5g water, after stirring 1 minute to formation clear solution, add the former medicine of lythidathion of 2g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 16.7% lythidathion aqua.
Gained homogeneous transparent state solution, leaves standstill 2h, without crystallization or lamination.Cold storage stability and thermodynamic stability is investigated respectively-5 DEG C and 54 ± 2 DEG C, cold or thermmal storage is still stable after 14 days, the results are shown in Table 1.
Embodiment 2:
Taking 2.5g1-octyl group-3-methylimidazole Pfansteihl salt adds in 7.5g water, after stirring 1 minute to formation clear solution, add the former medicine of lythidathion of 1.3g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 11.5% lythidathion aqua.
Embodiment 3:
Taking 3.0g1-octyl group-3-methylimidazole Pfansteihl salt adds in 7.0g water, after stirring 1 minute to formation clear solution, add the former medicine of lythidathion of 4.3g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 30% lythidathion aqua.
Embodiment 4:
Taking 3g1-octyl group-3-methylimidazole Pfansteihl salt adds in 7g water, after stirring 1 minute to formation clear solution, add the pyrethrosin primary medicine of 0.45g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 3.8% pyrethrin aqua.
Embodiment 5:
Taking 3.0g1-butyl-3-methylimidazole L-PROLINE salt adds in 7.0g water, after stirring 1 minute to formation clear solution, add the pyrethrosin primary medicine of 0.13g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 1.3% pyrethrin aqua.
Embodiment 6:
Taking 3.0g1-butyl-3-methylimidazole L-PROLINE salt adds in 7.0g water, after stirring 1 minute to formation clear solution, add the pyrethrosin primary medicine of 1.25g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 11.1% pyrethrin aqua.
Embodiment 7:
Taking 3.0g1-butyl-3-methylimidazole L-PROLINE salt adds in 7.0g water, after stirring 1 minute to formation clear solution, add the former medicine of cyromazine of 0.7g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 10% cyromazine aqua.
Embodiment 8:
Taking 2.5g1-butyl-3-methylimidazole L-PROLINE salt adds in 7.5g water, after stirring 10 minutes to formation clear solution, add the former medicine of cyromazine of 0.1g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 1% cyromazine aqua.
Embodiment 9:
Taking 3.0g1-butyl-3-methylimidazole L-PROLINE salt adds in 7.0g water, after stirring 10 minutes to formation clear solution, add the former medicine of cyromazine of 0.5g, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains 5% cyromazine aqua.
Embodiment 1 ~ 9 physicochemical property assay is in table 1.
Table 1 physicochemical property
Although above with general explanation, embodiment and example, the present invention is described in detail, on basis of the present invention, certain supplementing and optimize can be made to the discrimination model of this method.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (2)
1. be an aqua type pesticidal preparations for cosolvent preparation with ionic liquid, it is characterized in that, the mixture be made up of ionic liquid, water, pesticide original medicine, wherein ionic liquid content is 20% ~ 30%, and all the other are supplied by water;
Wherein, described pesticide original medicine is the former medicine of lythidathion, and pesticide original medicine content is 11.5% ~ 30%; Or described pesticide original medicine is pyrethrosin primary medicine, pesticide original medicine content is 3% ~ 12%; Or described pesticide original medicine is the former medicine of cyromazine, and pesticide original medicine content is 1%-10%;
Wherein, described ionic liquid is 1-octyl group-3-methylimidazole Pfansteihl salt or 1-butyl-3-methylimidazole L-PROLINE salt.
2. aqua type pesticidal preparations according to claim 1, is characterized in that, adopts following steps preparation:
Take ionic liquid and water in proportion, mixing, after stirring 1 minute to formation clear solution, add pesticide original medicine, then ultrasonic dissolution is to forming clear homogeneous solution, namely obtains aqua type pesticidal preparations.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104920352B (en) * | 2015-07-17 | 2017-11-03 | 中国农业大学 | A kind of pesticidal preparations using ion liquid of quaternaries as cosolvent |
| CN105123747B (en) * | 2015-09-08 | 2017-04-12 | 天津蕴农科技有限公司 | Fosthiazate soluble liquid agent for killing nematodes and preparation method thereof |
| CN112674106B (en) * | 2021-01-06 | 2021-12-07 | 沈阳农业大学 | Soluble agent and preparation method thereof |
| CN114532335B (en) * | 2022-03-04 | 2023-04-25 | 上海师范大学 | Ionic liquid pesticide microcapsule and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258011A (en) * | 2011-06-03 | 2011-11-30 | 中国农业大学 | Bactericidal pesticide preparation by taking ionic liquid as cosolvent and preparation method thereof |
| CN102308788A (en) * | 2011-07-07 | 2012-01-11 | 中国农业大学 | Insecticidal agricultural pesticide preparation using ionic liquid as cosolvent and method for preparing insecticidal agricultural pesticide preparation |
| CN102715150A (en) * | 2012-06-27 | 2012-10-10 | 中国农业大学 | Weeding pesticide preparation using ionic liquid as cosolvent and preparation method of weeding pesticide preparation |
| CN102939956A (en) * | 2012-11-21 | 2013-02-27 | 扬州大学 | Method for preparing novel controllable release pesticide formulation based on biological compatible soft materials |
| WO2014128009A1 (en) * | 2013-02-19 | 2014-08-28 | Basf Se | Aqueous agrochemical composition comprising a pesticide in suspended form, a dispersant, and an ionic liquid |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258011A (en) * | 2011-06-03 | 2011-11-30 | 中国农业大学 | Bactericidal pesticide preparation by taking ionic liquid as cosolvent and preparation method thereof |
| CN102308788A (en) * | 2011-07-07 | 2012-01-11 | 中国农业大学 | Insecticidal agricultural pesticide preparation using ionic liquid as cosolvent and method for preparing insecticidal agricultural pesticide preparation |
| CN102715150A (en) * | 2012-06-27 | 2012-10-10 | 中国农业大学 | Weeding pesticide preparation using ionic liquid as cosolvent and preparation method of weeding pesticide preparation |
| CN102939956A (en) * | 2012-11-21 | 2013-02-27 | 扬州大学 | Method for preparing novel controllable release pesticide formulation based on biological compatible soft materials |
| WO2014128009A1 (en) * | 2013-02-19 | 2014-08-28 | Basf Se | Aqueous agrochemical composition comprising a pesticide in suspended form, a dispersant, and an ionic liquid |
Non-Patent Citations (1)
| Title |
|---|
| 离子液体表面活性剂在农药剂型中的应用;林娟等;《中国化学会第28届学术年会第12分会场摘要集》;20120413;正文 * |
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