CN1043846C - Traditional Chinese medicine preparation for mainly curing myopia - Google Patents
Traditional Chinese medicine preparation for mainly curing myopia Download PDFInfo
- Publication number
- CN1043846C CN1043846C CN94104076A CN94104076A CN1043846C CN 1043846 C CN1043846 C CN 1043846C CN 94104076 A CN94104076 A CN 94104076A CN 94104076 A CN94104076 A CN 94104076A CN 1043846 C CN1043846 C CN 1043846C
- Authority
- CN
- China
- Prior art keywords
- medicine
- chinese medicine
- chinese
- preparation
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a traditional Chinese medicine preparation mainly curing myopia and a preparation method thereof. The preparation is composed of one or some of the following traditional Chinese medicines of chrysanthemum, schisandra fruit, nacre, semen cassiae, hedge prinsepia nut, wolfberry fruit, concha haliotidis and pagodatree flower bud, wherein the dosage of each traditional Chinese medicine is respectively from 2.5g to 50g.
Description
The present invention relates to a kind of Chinese medicine composition, particularly a kind of Chinese medicine composition of main treatment myopia disease.
Myopia is a kind of commonly encountered diseases and frequently-occurring disease, particularly teenager, because multiple factor is often easily suffered from this disease.In the prior art, the ways and means of treatment and correct myopia eye emerges in an endless stream.The wherein main method that adopts is nothing more than being operation, medicine and various instrument.For example, CN 91197566.6 discloses a kind of preparation method of Chinese medicine for the treatment of pseudomyopia, wherein adopts the Chinese medicine Flos Chrysanthemi, Placenta Hominis, and Rhizoma Chuanxiong, Radix Glycyrrhizae Preparata, Herba Senecionis Scandentis, Semen Cassiae, 10 plurality of Chinese such as Radix Angelicae Sinensis are made a kind of eye drop by certain prescription.In addition, CN91103283.5 also discloses a kind of medicine pill for the treatment of children's myopia using, and its raw material comprises Radix Codonopsis, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Bupleuri, Radix Salviae Miltiorrhizae, Radix Rehmanniae Preparata, 12 flavor Chinese medicines such as the Rhizoma Atractylodis Macrocephalae.There are many unsatisfactory parts in above-mentioned ways and means, and its reason is known.
The object of the present invention is to provide a kind of Chinese medicine preparation of curing nearsight and the method that preparation changes Chinese medicine preparation.
In order to finish the present invention's purpose, the following technical scheme of special employing:
The present invention's Chinese medicine preparation can be made up of one or more Chinese medicines of selecting in the following traditional Chinese medicines: Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, the dosage of wherein said each Chinese medicine are respectively the 2.5-50 gram.
Preferably, the present invention's Chinese medicine preparation can be made up of Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, and wherein above-mentioned dosage of respectively distinguishing the flavor of Chinese medicine is respectively the 2.5-50 gram.
The preparation method of the present invention's Chinese medicine preparation can comprise:
1. get one or more the former medicines in Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, put it into respectively in the Chinese liquor of 30-60 degree, soaking at room temperature 8-72 hour, reach sterilization functions simultaneously;
2. discard described Chinese liquor, the former medicine after obtaining soaking;
3. the described former medicine of heating, drying;
4. the dosage by the above-mentioned Chinese medicine of every flavor is that the prescription that 2.5-50 restrains is deployed into a medicine;
5. pulverize this medicine, sieve, make medicated powder.
The preparation method of the present invention's Chinese medicine preparation also can comprise:
1. get Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, put it into respectively in the Chinese liquor of 30-60 degree, soaking at room temperature 8-72 hour, reach sterilization functions simultaneously;
2. discard described Chinese liquor, the former medicine after obtaining soaking;
3. the described former medicine of heating, drying;
4. the dosage by the above-mentioned Chinese medicine of every flavor is that the prescription that 2.5-50 restrains is deployed into a mixture;
5. pulverize this mixture, sieve, make medicated powder.
The above-mentioned medicated powder of making can further be processed into powder or capsule.As powder, obey secondary 5g day for every bag and sooner or later take after mixing it with water one bag.
The present invention has following advantage:
1, Chinese medicine preparation of the present invention is treatment adolescent myopia, hypermetropia, amblyopia, scattered-light specific medicament.Take medicine today and take effect tomorrow, long-term efficacy is arranged, treating both the principal and the secondary aspects of a disease at the same time.
2, Chinese medicine preparation of the present invention has nourishing the liver and kidney, beneficial marrow, qi and blood invigorating, blood circulation promoting and blood stasis dispelling, heat clearing away YIN nourishing, stimulates the menstrual flow, has one's ideas straightened out, makes eye bright.The flat horizontal QI and blood abundance of negative and positive is so disease spontaneous recovery.Think that in theory heat moves back then cloudy giving birth to, cloudyly give birth to that then essence and blood is long, liver opening at eye, the refreshing light in Heisui River belongs to kidney, and two dirty cloudy gas gain, and then order is bright.
3, prescription essence of the present invention, flavour of a drug are few, no side effects, curative effect is reliable, the cure rate height.
Traditional theory of Chinese medical science is thought Flos Chrysanthemi, nature and flavor sweetness and bitterness, cold.Record ＂ supports bleeding of eye ＂ in " pearl sac ", says in " medication heart method " that it has the ＂ ＂ effect that makes eye bright; Fructus Schisandrae Chinensis nature and flavor acid temperature says that it makes eye bright in nontoxic " Japan hanako materia medica "; The sweet cold of Concha Margaritifera nature and flavor, nontoxic, liver nourishing the moon, clearing away liver-fire makes eye bright; The Semen Cassiae nature and flavor are sweet, and cold is nontoxic, and optic atrohic blindness is controlled in clearing away heat to improve acuity of vision, and the clothes benefit is with nothing left for a long time; The Nux Prinsepiae nature and flavor are sweet, and are cold, nontoxic, dispel the wind heat radiation, nourishing the liver to improve visual acuity; The Fructus Lycii nature and flavor are sweet flat, nontoxic, nourishing kidney, and tonifying liver makes eye bright; Concha Haliotidis nature and flavor Cheng Ping, nontoxic, suppressing the hyperactive liver and subsiding YANG, heat extraction makes eye bright; The Flos Sophorae Immaturus has the record of the retinitis of treatment diabetes in " the northeast medicine is planted will ".(Chinese medicine dictionary, Shanghai science tech publishing house, 1986,6 editions)
Experimental example 1
The acute toxicity test of Chinese medicine preparation of the present invention is as follows:
One, experiment material
The Chinese medicinal powder that the embodiment of the invention 1 obtains, lot number 921021 (sampling on October 21 in promptly 92 year) offers the institute for drug control, Heilongjiang Province and experimentizes, and Kunming mouse is provided by this animal housing.
Two, experimental technique
1, medicine is handled: get above-mentioned medicated powder and put porphyrize in the mortar, cross 100 mesh sieves.Be mixed with the suspension of 24% concentration with aquae destillata, for gastric infusion.Other gets this medicated powder and adds aquae destillata decoction 0.5 hour, and is centrifugal, filters, and precipitate adds water to be handled once by last method again, merges filtrate twice, makes the solution that contains crude drug amount 60% concentration, uses for lumbar injection.
2, oral administration gives the lethal dose that test fails to propose mice.10 of 18-21g mices are got in formal test, and male and female half and half are irritated stomach 0.8ml with the every Mus of 24% concentration liquid.Examine the reaction of each Mus after the administration, and write down death toll in 7 days.Each Mus body weight gain after the administration as a result, diet is normal, does not see the overt toxicity reaction, 10 mices do not have do not take place dead.This moment, the mice dosage was 9.6/Kg.
According to middleization people's republic new drug approval regulation, do the acute toxicity test of multiple dosing in 1 day again.
Other gets 10 of 18-21g mices, male and female half and half.Irritate stomach 0.8ml with the every Mus of 24% concentration liquid at every turn, every 5 hours once, continuous 3 times.Each Mus weight increase after the administration, hair luster, diet, two is just all normal.10 all acomia life and death of mice are died in 7 days.
3, intraperitoneal injection is got 10 of 18-21g mices, male and female half and half.Lumbar injection contains the water extract of crude drug amount 60%, every Mus shot 0.5ml.Observe the toxic reaction of each Mus then, and write down dead mouse number in 7 days.Result mice in back 1 hour of injection flocks together, the movable minimizing.Recover normal later on, do not see the overt toxicity reaction, none generation of mice is dead in 7 days.This moment, the mice dosage was 6g/Kg.
Three, brief summary
The dosis tolerata of a gastric infusion of this experiment mice reaches 9.6g/Kg.And give 3 administrations in the mice 1 day with this dosage, do not see that animal takes place dead yet.This liquid medicine extracting solution reaches 6g/Kg to mouse peritoneal injection dosis tolerata.Above-mentioned three experiments there is no tangible toxic reaction and animal dead.Show that this poison of drug property is extremely low.Experimental example 2
Treat near-sighted clinical observation on the therapeutic effect and adopt the Chinese medicine of the following enforcement side 2 of the present invention to carry out clinical observation 103 examples, its result is as follows for observation analysis:
Clinical money section
Treatment target is that the outpatient service aspiration requires therapist.Inspection item (logarithmic visual acuity chart, subjective optometry, optical fundus etc.) and 103 more complete examples of registration card that statistics carries out for regulation, 197 eyes, wherein male 47 examples, 89 eyes, women 56 examples, 108 eyes.The myopia vision sees Table one, and its myopic degree sees Table two, and age distribution sees Table three.Curative effect determinate standard sees Table four.
The near-sighted information slip of table one
The bathomorphic ametropia table of degree of table two
The near-sighted age distribution table of table three
| Vision | The eye number | ％ | Vision | The eye number | ％ |
| ≤4.0 | 14 | 7.1 | 4.5 | 33 | 16.7 |
| 4.1 | 6 | 3.0 | 4.6 | 19 | 9.6 |
| 4.2 | 20 | 10.0 | 4.7 | 28 | 14.2 |
| 4.3 | 21 | 10.6 | 4.8 | 18 | 9.1 |
| 4.4 | 31 | 15.7 | 4.9 | 7 | 3.5 |
| Myopic degree | Slightly | Moderate | Highly | Add up to |
| Eye number (only) | 52 | 83 | 62 | 197 |
| ％ | 26 | 43 | 31 | 100％ |
| Age (year) | ≤10 | ～12 | ～14 | ～18 | ～18 | ～20 | ＞20 |
| The eye number | 40 | 48 | 42 | 22 | 10 | 14 | |
| 20.30 | 10.85 | 21.86 | 21.31 | 11.16 | 5.0＞ | 7.1 |
Therapeutic Method
1, be defined as on inspection ametropic in conjunction with throw giving powder of the present invention after optical fundus and the optometry 5.0g/ time one day twice, warm water delivery service, 10 days is a course of treatment.
2, points for attention: prohibit during the treatment and see TV, video and Play Station games, novel.
Observation of curative effect
Curative effect determinate standard: table four curative effect determinate standard
| Curative effect | Treatment back vision improves line number | The eye number | ％ |
| Effectively | 〉=2 row | 185 | 93.90 |
| Produce effects | 3-5 capable (being lower than 4.9) | 41 | 20.81 |
| Basic cure rate | 〉=3 row (reaching 5.0) | 114 | 57.87 |
| Cure | 〉=6 row (being higher than 5.0) | 30 | 15.22 |
| Invalid | ＜2 row (no change) | 12 | 6.0 |
Annotate: calculate with logarithmic visual acuity chart nature line number.
Brief summary
1, motherland's medical science thinks that teenager is the vigorous time of growth of " long QI and blood, spermatogenesis god, Fructus Alpiniae Oxyphyllae are intelligent ", to being in great demand of QI and blood, also belongs to the body of " the young sun of young the moon ", the deficient eyes of QI and blood easily takes place lose and support and cause myopia.Medicine confirms that through clinical observation clinical effective rate is 93.90% promptly at this etiopathogenesis among the present invention, and basic cure rate is 57.87% (reaching 5.0), obvious effective rate 20.81%, cure rate 15.22% (being higher than 5.0), and inefficiency 6.0%.Total cure rate reaches 73.2%.
2, this group case combines in 10～18 years old juvenile group of person more, and adult group is less, and other oculopathy is not related to.
3,103 examples of Guan Chaing are taken medicine the stage trimestral, and are the shortest in a course of treatment, and the longest eight courses of treatment, most continuous was taken medicine 30～50 days.
4, the strict vision check of grasping after taking medicine, minimum more than 2 times, special case is up to 9 times more than.Experimental example 3
Indivedual medical records: Zhai xx, the woman, 12 years old, be Harbin power-section Wang Zhao primary school student, clinical diagnosis is an amblyopia, naked vision 0.3, after the Chinese medicine preparation that adopts the following embodiment 3 of the present invention to make was treated in 25 days, eyes reached 1.2 respectively.Experimental example 4
Indivedual medical records: all xx, the woman 15 years old, is Harbin railway one middle school student.Clinical diagnosis is myopia 350 degree, astigmatism 150, and eyes are naked to be considered as 0.2, the preparation for treating through adopting following embodiment 1 45 days, its eyes reach 1.2 respectively.Experimental example 5
Indivedual medical records: horse x, man, 14 years old, Heilongjiang Province's Heihe City two middle school student.Clinical diagnosis is a hypermetropia, and naked vision is 0.3, the preparation for treating through adopting the following embodiment 4 of the present invention 30 days, and its binocular vision reaches 1.0.Embodiment 1
Get the former medicine of Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, Nux Prinsepiae will be removed the peel shell, deoils with grease press, in the Chinese liquor that puts it into 30 degree respectively, former medicine is crossed in the Chinese liquor desert, and soaking at room temperature reaches sterilization functions more than 8 hours simultaneously.Discard described Chinese liquor then, the above-mentioned former medicine after obtaining soaking.With the described former medicine of medicine roasting machine heating, drying.Dosage by the above-mentioned Chinese medicine of every flavor is that 2.5 prescriptions that restrain are deployed into a medicinal mixture, pulverizes this medicinal mixture with cracker for medicine, crosses 60 mesh sieves, makes a medicated powder.
The medicated powder that obtains can pack through aluminum is thin with racking machine, be made the product that per generation 5 restrains.Embodiment 2
Get the former medicine of Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, Nux Prinsepiae will be removed the peel shell, deoils with grease press, in the Chinese liquor that puts it into 60 degree respectively, former medicine is crossed in the Chinese liquor desert, and soaking at room temperature 72 hours reaches sterilization functions simultaneously.Discard described Chinese liquor then, the above-mentioned former medicine after obtaining soaking.With the described former medicine of medicine roasting machine heating, drying.Dosage by the above-mentioned Chinese medicine of every flavor is that 50 prescriptions that restrain are deployed into a medicinal mixture, pulverizes this medicinal mixture with cracker for medicine, crosses 60 mesh sieves,
Make a medicated powder.
The medicated powder that obtains adopts known method that it is incapsulated, and makes oral capsule.Embodiment 3
Get the former medicine of Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, Nux Prinsepiae will be removed the peel shell, deoils with grease press, and in the Chinese liquor that puts it into 56 degree respectively, former medicine is crossed in the Chinese liquor desert, and soaking at room temperature 24 hours reaches sterilization functions simultaneously.Discard described Chinese liquor then, the above-mentioned former medicine after obtaining soaking.With the described former medicine of medicine roasting machine heating, drying.Dosage by the above-mentioned Chinese medicine of every flavor is that 50 prescriptions that restrain are deployed into a medicinal mixture, pulverizes this medicinal mixture with cracker for medicine, crosses 60 mesh sieves, makes a medicated powder.Embodiment 4
Flos Chrysanthemi is put into 35 Chinese liquor of spending, and former medicine is crossed in the Chinese liquor desert, and soaking at room temperature 24 hours reaches sterilization functions simultaneously.Discard described Chinese liquor then, the above-mentioned former medicine after obtaining soaking.With the described former medicine of medicine roasting machine heating, drying.Pulverize this medicinal mixture with cracker for medicine, cross 40 mesh sieves, make a medicated powder.
Claims (1)
1, the bathomorphic Chinese medicine preparation of a kind of treatment, it is characterized in that, this Chinese medicine preparation is to be made by Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus, wherein, above-mentioned dosage of respectively distinguishing the flavor of Chinese medicine is equivalent, and described Chinese medicine preparation prepares as follows:
1) gets in the Chinese liquor that Flos Chrysanthemi, Fructus Schisandrae Chinensis, Concha Margaritifera, Semen Cassiae, Nux Prinsepiae, Fructus Lycii, Concha Haliotidis and the Flos Sophorae Immaturus put it into the 30-60 degree respectively soaking at room temperature 8-72 hour;
2) abandon described Chinese liquor, the former medicine after must soaking;
3) the described former medicine of heating, drying;
4) prescription by the dosage of the above-mentioned Chinese medicine of every flavor is deployed into a medicine;
5) pulverize this medicine, sieve, make medicated powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN94104076A CN1043846C (en) | 1994-04-14 | 1994-04-14 | Traditional Chinese medicine preparation for mainly curing myopia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN94104076A CN1043846C (en) | 1994-04-14 | 1994-04-14 | Traditional Chinese medicine preparation for mainly curing myopia |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 97104354 Division CN1166349A (en) | 1997-05-28 | 1997-05-28 | Chinese medicine preparation mainly for curing myopia |
| CN 97104315 Division CN1174719A (en) | 1997-05-28 | 1997-05-28 | Traditional Chinese medicine for curing nearsight |
| CN97104314A Division CN1064249C (en) | 1997-05-28 | 1997-05-28 | Traditional Chinese medicine for indication nearsight |
| CN 97104355 Division CN1166350A (en) | 1997-05-28 | 1997-05-28 | Chinese medicine preparation mainly for curing myopia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1110161A CN1110161A (en) | 1995-10-18 |
| CN1043846C true CN1043846C (en) | 1999-06-30 |
Family
ID=5031410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN94104076A Expired - Fee Related CN1043846C (en) | 1994-04-14 | 1994-04-14 | Traditional Chinese medicine preparation for mainly curing myopia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1043846C (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1310667C (en) * | 2005-09-29 | 2007-04-18 | 李广中 | Nebula removing pills |
| CN104825646A (en) * | 2015-04-16 | 2015-08-12 | 湖州品创孵化器有限公司 | Traditional Chinese medicinal composition for treating myopia |
| CN104983905A (en) * | 2015-06-30 | 2015-10-21 | 覃健峰 | Eyesight improving capsule |
| CN105663502A (en) * | 2016-01-19 | 2016-06-15 | 王鹏程 | Medicine for treating nearsightedness and preparation method thereof |
| CN109847045A (en) * | 2018-12-28 | 2019-06-07 | 袁秀 | Activate heat toast composition, hot moxibustion bag and the preparation method of ocular cell vis medicatrix naturae |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1039726A (en) * | 1989-09-04 | 1990-02-21 | 罗勇 | Chinese medicine make eye bright crystal formulations and production method thereof |
| CN1077388A (en) * | 1993-03-04 | 1993-10-20 | 金瑛 | Prescription for treating eye diseases by external application on navel |
-
1994
- 1994-04-14 CN CN94104076A patent/CN1043846C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1039726A (en) * | 1989-09-04 | 1990-02-21 | 罗勇 | Chinese medicine make eye bright crystal formulations and production method thereof |
| CN1077388A (en) * | 1993-03-04 | 1993-10-20 | 金瑛 | Prescription for treating eye diseases by external application on navel |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1110161A (en) | 1995-10-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1596914A (en) | Medicine for treating eye disease caused by visceral disease | |
| CN1895547B (en) | Medicine for treating diabetes and its preparation | |
| CN1043846C (en) | Traditional Chinese medicine preparation for mainly curing myopia | |
| CN102847061A (en) | Traditional Chinese medicine preparation for treating pediatric viral myocarditis and preparation method thereof | |
| CN108635389A (en) | A kind of preparation method of Chinese medicine preparation and its electuary that treating diabetes B | |
| CN1064249C (en) | Traditional Chinese medicine for indication nearsight | |
| CN103356901A (en) | Medicine for curing dampness-heat of spleen and stomach and preparation method thereof | |
| CN1294949C (en) | Chinese medicinal preparation for treating sexual dysfunction, menoxenia, aciesis and developing immunity | |
| CN103393938B (en) | Traditional Chinese medicine composition for reducing blood sugar | |
| CN102552677B (en) | Coptis chinensis and radix rehmanniae Anxiao capsule and preparation method thereof | |
| CN1517115A (en) | Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation | |
| CN1166349A (en) | Chinese medicine preparation mainly for curing myopia | |
| CN1174719A (en) | Traditional Chinese medicine for curing nearsight | |
| CN1158091C (en) | Chinese medicine composition for treating lung cancer | |
| CN1166350A (en) | Chinese medicine preparation mainly for curing myopia | |
| CN104324139B (en) | A kind of pharmaceutical composition treating xerophthalmia | |
| CN103520684A (en) | Traditional Chinese medicine compound for reducing blood sugar | |
| CN103536879A (en) | Pharmaceutical composition for treating diabetes mellitus and preparation method thereof | |
| CN102579831A (en) | Immunotherapy of treating cancer through snuffing and steaming traditional Chinese medicine | |
| CN1101559A (en) | Traditional Chinese medicine oral administration liquid for anti-cancer and its preparing method | |
| CN111110782B (en) | Application of traditional Chinese medicine composition in preparation of medicine for treating cold | |
| CN106166206A (en) | A kind of gynecological inflammation causes the rehabilitation medicine preparation method of frequent micturition | |
| CN105998519A (en) | Oral medicine for treating frequent micturition due to pelvic inflammatory disease | |
| CN106177389B (en) | Traditional Chinese medicine preparation with functions of relaxing bowel, improving sleep and enhancing immunity and preparation method thereof | |
| CN100335111C (en) | Medicine for rheumatism and its preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |