CN104383464A - 一种治疗卵巢癌的中药组合物 - Google Patents

一种治疗卵巢癌的中药组合物 Download PDF

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CN104383464A
CN104383464A CN201410757554.6A CN201410757554A CN104383464A CN 104383464 A CN104383464 A CN 104383464A CN 201410757554 A CN201410757554 A CN 201410757554A CN 104383464 A CN104383464 A CN 104383464A
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高田田
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Abstract

本发明公开了一种治疗卵巢癌的中药组合物,属于中药技术领域,由下述原料制备而成:半夏,莪术,白术,没药,杜仲,杏仁,赤芍,远志,泽泻,续断,元胡,地龙,木香,党参,郁金,细辛,柴胡,当归,桑寄生,人参,穿山甲,麦冬,熟地,独活,黄芪,女贞子,车前子,夏枯草,川芎。本发明中药将上述药物组合后,其药效协同作用,具有补气益精、养血舒肝、软坚散结、活血化瘀的功效,抑制癌细胞生长扩散,治疗卵巢癌见效快,疗效确切,可以有效控制癌细胞转移扩散,能够增强机体免疫功能以达到抑制癌细胞生长,防止残存癌细胞卷土重来,杜绝复发转移。

Description

一种治疗卵巢癌的中药组合物
技术领域
[0001] 本发明涉及一种中药制剂,具体说是一种治疗卵巢癌的中药组合物。
背景技术
[0002] 卵巢癌是发生于卵巢组织的恶性肿瘤。国内外临床资料统计,其五年生存率仅25%〜30%。卵巢癌的病因尚不清楚,其发病可能与年龄、生育、血型、精神因素及环境等有关。本病在临床上可出现下腹不适、腹痛、腹部肿块、月经紊乱、压迫等症状。
[0003] 卵巢癌的西医治疗方式以手术治疗,放射治疗,化学治疗为主。这些疗法虽然见效快,但只能解决局部问题,易复发,副作用大。中医中药治疗癌症可减轻病人的症状和痛苦,且副作用小,配合西医治疗,可最大限度地延长病人的生存时间。
发明内容
[0004] 本发明的目的在于提供一种治疗卵巢癌的中药组合物,全部选用天然中草药,能够有效治疗卵巢癌。
[0005] 本发明解决技术问题所采取的技术方案是:
[0006] 一种治疗卵巢癌的中药组合物,其特征在于,由以下重量的中药制成:
[0007] 半夏5 — 15克,莪术5 — 15克,白术5 — 15克,没药5 — 15克,杜仲5 — 15克,杏仁5 — 15克,赤芍5 — 15克,远志5 — 15克,泽泻5 — 15克,续断10 — 20克,元胡10 —20克,地龙10 — 20克,木香10 — 20克,党参10 — 20克,郁金10 — 20克,细辛10 — 20克,柴胡10 — 20克,当归10 — 20克,桑寄生10 — 20克,人参10 — 20克,穿山甲10 — 20克,麦冬10 — 20克,熟地10 — 20克,独活10 — 20克,黄芪15 — 25克,女贞子15 — 25克,车前子15 - 25克,夏枯草15 - 25克,川芎15 — 25克。
[0008] 优选的,由以下重量的中药制成:
[0009] 半夏10克,莪术10克,白术10克,没药10克,杜仲10克,杏仁10克,赤芍10克,远志10克,泽泻10克,续断15克,元胡15克,地龙15克,木香15克,党参15克,郁金15克,细辛15克,柴胡15克,当归15克,桑寄生15克,人参15克,穿山甲15克,麦冬15克,熟地15克,独活15克,黄芪20克,女贞子20克,车前子20克,夏枯草20克,川芎20克。
[0010] 配制及服用方法:
[0011] 将原料混合入砂锅内,加水适量泡透;先武火煎沸,再以文火煎半小时,滤出药液,药渣内加水适量再煎半小时,再滤出药液。两次药液混合、凉透,分别于早饭前半小时,晚饭后两小时服用。30天为一疗程。
[0012] 各中药的药理作用:
[0013] 半夏:燥湿经痰,降逆止呕,消痞散结。治湿痰冷饮,呕吐反胃,痰厥头痛,头晕不眠。
[0014] 莪术:苦辛,温。入肝、脾经。破血行气,消积止痛。用于血瘀腹痛、肝脾肿大、心腹胀痛,积聚,妇女血瘀经闭,跌打损伤作痛饮食积滞。
[0015] 白术:苦甘,温。入脾、胃经。补脾,益胃,燥湿,和中,安胎。治脾胃气弱,不思饮食,倦怠少气,虚胀,泄湾,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。
[0016] 没药:苦,辛,平,无毒。肝,脾,心,肾经。活血定痛,消肿生肌,主治跌打损伤,金疮,筋骨,心腹诸痛,症瘕,经闭,痈疽肿痛,疮疡溃后久不收口。
[0017] 杜仲:入肝、肾经。补肝肾,强筋骨,安胎。治腰脊酸疼,足膝痿弱,小便余浙,阴下湿痒,胎漏欲堕,胎动不安,高血压。
[0018] 杏仁:祛痰止咳,平喘,润肠。治外感咳嗽,喘满,喉痹,肠燥便秘。
[0019] 赤芍:苦,微寒。归肝经。清热凉血,散瘀止痛。用于温毒发斑,吐血衄血,目赤肿痛,肝郁胁痛,经闭痛经,癥瘕腹痛,跌扑损伤,痈肿疮疡。
[0020] 远志:安神益智,祛痰,解郁。治惊悸,健忘,梦遗,失眠,咳嗽多痰,痈疽疮肿。
[0021] 泽泻:甘,寒。入肾、膀胱经。利水,渗湿,泄热。治小便不利,水肿胀满,呕吐,泻痢,痰饮,脚气,淋病,尿血。
[0022] 续断:补肝肾,续筋骨,调血脉。治腰背酸痛,足膝无力,胎漏,崩漏,带下,遗精,跌打损伤,痔漏,痈疽疮肿。
[0023] 元胡:辛、苦,温,归肝,心,胃经,活血化淤,行气止痛,善治内、外诸痛,广泛应用于胸痹心痛、肝胃气痛、痛经、积聚腹痛、跌打肿痛、筋骨疼痛。研究证实:本品含延胡索乙素等成分,具有镇静,镇痛作用。
[0024] 地龙:清热,平肝,止喘,通络。治高热狂躁,惊风抽搐,风热头痛,目赤,中风半身不遂,喘息,喉痹,关节疼痛,齿衄,小便不通,瘰疬。
[0025] 木香:气芳香,味甜、苦,稍刺舌。性温,味辛、苦。行气止痛,健脾消食。用于胸腺胀痛、泻痢后重、食积不消、不思饮食。
[0026] 党参:甘,平。入手、足太阴经气分。补中益气,生津,养血。用于中气不足的体虚倦怠,脾胃虚弱,气血两亏,治体倦无力,肺气亏虚。治食少,口渴,久泻,脱肛。及气血双亏的面色萎黄,头晕心悸等。
[0027] 郁金:辛苦,凉。入心、肺、肝经。行气解郁,凉血破瘀,治胸腹胁肋诸痛,失心癫狂,热病神昏.吐血,黄疸。
[0028] 细辛:辛,温。入肺、肾经。具有散寒解表、祛风除湿、活血化瘀、消炎止痛、清热解毒等功效.治风冷头痛,鼻渊,齿冷,风湿痹痛。
[0029] 柴胡:辛、微苦、微寒;归肝、胆经。解表退热,舒肝解郁,升举阳气。本品疏达善透,长于疏解肝胆郁热,又能疏肝理气,为治疗肝胆郁热、肝郁气滞所致胁肋疼痛要药。
[0030] 当归:甘辛,温。入心、肝、脾经。补血和血,调经止痛,润燥滑肠。治月经不调,经闭腹痛,癥瘕结聚,崩漏;血虚头痛,眩晕,痿痹;肠燥便难,赤痢后重;痈疽疮窃,跌扑损伤。
[0031] 桑寄生:补肝肾,强筋骨,除风湿,通经络,益血,安胎。治腰膝酸痛,筋骨痿弱,风寒湿痹,胎漏血崩。
[0032] 人参:味甘,微温,无毒。入脾、肺经。大补元气,固脱生津,安神。治劳伤虚损,食少,倦怠,反胃吐食,大便滑泄,虚咳喘促,自汗暴脱,惊悸,健忘,眩晕头痛,阳痿,尿频,消渴,妇女崩漏,小儿慢惊,及久虚不复,一切气血津液不足之证。
[0033] 穿山甲:消肿溃痈,搜风活络,通经下乳。治痈疽疮种,风寒湿痹,月经停闭,乳汁不通。
[0034] 麦冬:甘,微苦,微寒。归心、肺、胃经。养阴生津,润肺清心。用于肺燥干咳,虚痨咳嗽,津伤口渴,心烦失眠,内热消渴,肠燥便秘,咽白喉。
[0035] 熟地:既善补血滋阴,又能补精益髓,主治一切血虚阴亏精少之症。主要功能养血滋阴、补精益髓,用于血虚萎黄、眩晕、心悸。
[0036] 独活:辛苦,温。入肾、膀胱经。祛风,胜湿,散寒,止痛。治风寒湿痹,腰膝酸痛,手脚挛痛,慢性气管炎,头痛,齿痛。
[0037] 黄芪:性温,味甘。补气升阳,益卫固表、托毒生肌、利水退肿。主治脾胃虚弱,食少倦怠,气虚血脱,表虚自汗、盗汗。
[0038] 女贞子:苦甘、平。入肝、肾经。补肝肾,强腰膝。治阴虚内热,头晕,目花,耳鸣,腰膝酸软,须发早白。滋补肝肾,明目乌发。用于眩晕耳鸣,腰膝酸软、须发早白、目暗不明。
[0039] 车前子:利水,清热,明目,祛痰。治小便不通,淋浊,带下,尿血,暑湿泻痢,咳嗽多痰,湿痹,目赤障翳。
[0040] 夏枯草:苦辛,寒。入肝、胆经。清肝,散结。治瘰疬,瘿瘤,乳痈,乳癌,目珠夜痛,羞明流泪,头目眩晕,口眼歪斜,筋骨疼痛,肺结核,急性黄疸型传染性肝炎,血崩,带下。
[0041] 川芎:味辛,温。入肝、胆经。行气开郁,法风燥湿,活血止痛。治风冷头痛旋晕,胁痛腹疼,寒痹筋挛,经闭,难产,产后瘀阻块痛,痈疽疮疡。用于月经不调,经闭痛经,瘕腹痛,胸胁刺痛,跌扑肿痛,头痛,风湿痹痛。
[0042] 中医认为卵巢癌属于中医的“症瘕”、“积聚”范畴。卵巢癌的发病,是由于正气不足,邪气内胜而引起。本发明中药将上述药物组合后,其药效协同作用,具有补气益精、养血舒肝、软坚散结、活血化瘀的功效,抑制癌细胞生长扩散,治疗卵巢癌见效快,疗效确切,可以有效控制癌细胞转移扩散,能够增强机体免疫功能以达到抑制癌细胞生长,防止残存癌细胞卷土重来,杜绝复发转移。能在短期内缩小肿块,控制转移、减轻痛苦、稳定病情、延长生存期,甚至达到临床治愈。同时又不产生副作用,无论是在手术前后,还是化疗治疗的辅助治疗,均可采用本方治疗。
[0043] 以下结合临床资料及典型病例对本发明的有益效果进一步说明。
[0044] 一、临床观察
[0045] 1、临床资料
[0046] 选取2011年5月至2013年12月卵巢癌患者80例。年龄29〜73岁,平均年龄56.4岁。其中包括19例早期卵巢癌患者。
[0047] 2、诊断标准:
[0048] (I)临床诊断:
[0049] 主要依靠临床征象,如患者感腹胀、便秘、尿频,自觉腹部有包块等等。应首先行妇科检查,若在子宫旁扪及一侧或双侧囊性或实质性球形肿块及其他盆腔异常情况,均应进一步采用各种方法加以确诊。
[0050] (2)超声检查:
[0051] 可协助盆腔或腹部肿瘤的定位,其准确率高达90%以上;区分囊性或实性肿瘤、子宫或附件;鉴别卵巢肿瘤、腹水或包裹性积液。
[0052] (3)细胞学诊断:
[0053] 卵巢肿瘤合并腹水可做腹水穿刺查癌细胞。阴道后穹隆涂片查癌细胞虽阳性率不高,但对病人完全无害,故也不失为一种诊断方法。在某些卵巢肿瘤中,因分泌雌激素,尤其在绝经后涂片呈雌激素高度影响,可协助诊断。
[0054] 3、治疗方法:服用本发明药物,水煎煮,分两次早晚服用。30天为一疗程。
[0055] 4、疗效标准:
[0056] 参考实体瘤客观疗效通用指标。
[0057] 完全缓解(CR)——可见肿瘤完全消失超过一个月。
[0058] 部分缓解(PK)-病灶最大直径及其最大垂直直径的乘积缩小达50 %,其他病灶无增大,持续超过一个月。
[0059] 稳定(S)——病灶两径乘积缩小不足50 %,增大不超过25 %,持续超过一个月。
[0060] 进展⑵——病灶两径乘积增加25%以上。
[0061] 5、治疗结果:80例患者经过1〜5个疗程的治疗,临床治愈66例,好转8例,无效6例,总有效率92.5%。其中早期19例早期宫颈癌中有13例治愈(肿瘤全部消失,随访1年未复发)。
[0062] 结论:本方法疗效显著,无任何毒副作用,具有良好的临床应用前景。
[0063] 二、典型病例:
[0064] 病例1:胡女士,女,36岁。患卵巢癌做了手术,半年后又感到腹胀、腹痛,在当地医院做CT,显示膀胱肿物,子宫肿物(2.6*2.7cm),诊断癌症已复发,腹腔多有粘连,身体极度虚弱,后来服用本发明治疗宫颈癌的中药水蜜丸治疗两个疗程,疼痛消失,并可下床活动,继续服药3个疗程,肿块逐渐缩小,诸症消失,至今一年,未见复发。
[0065] 病例2:栾某某,女,47岁。患者两年前出现腹胀腹痛,做B超,被怀疑为卵巢肿瘤。后做进一步诊断,确诊为卵巢癌II期C。经手术治疗后回家休养。近期复发,病情十分严重,在当地医院接受化疗和放疗。但是,治疗效果很差,身体极度虚弱,难以继续化疗。服用本发明中药一个疗程,胸腹胀痛减轻,病情有较大缓解。原方加减继服两个疗程,患者睡眠好,腹痛、水肿消失,去医院复查时,报告显示,各项指标正常,身体康复的很好。如今患者已顺利度过五年生存期。
具体实施方式
[0066] 实施例1:一种治疗卵巢癌的中药组合物,由以下重量的中药制成:
[0067] 半夏10克,莪术10克,白术10克,没药10克,杜仲10克,杏仁10克,赤芍10克,远志10克,泽泻10克,续断15克,元胡15克,地龙15克,木香15克,党参15克,郁金15克,细辛15克,柴胡15克,当归15克,桑寄生15克,人参15克,穿山甲15克,麦冬15克,熟地15克,独活15克,黄芪20克,女贞子20克,车前子20克,夏枯草20克,川芎20克。
[0068] 配制及服用方法:
[0069] 将原料混合入砂锅内,加水适量泡透;先武火煎沸,再以文火煎半小时,滤出药液,药渣内加水适量再煎半小时,再滤出药液。两次药液混合、凉透,分别于早饭前半小时,晚饭后两小时服用。30天为一疗程。
[0070] 实施例2: —种治疗卵巢癌的中药组合物,由以下重量的中药制成:
[0071] 半夏10克,莪术10克,白术10克,没药10克,杜仲10克,杏仁10克,赤芍10克,远志10克,泽泻10克,续断10克,元胡10克,地龙10克,木香12克,党参12克,郁金12克,细辛12克,柴胡15克,当归15克,桑寄生15克,人参15克,穿山甲15克,麦冬15克,熟地15克,独活15克,黄芪20克,女贞子20克,车前子20克,夏枯草15克,川芎15克。
[0072] 配制及服用方法:同例I。
[0073] 实施例3: —种治疗卵巢癌的中药组合物,由以下重量的中药制成:
[0074] 半夏10克,莪术10克,白术15克,没药10克,杜仲10克,杏仁10克,赤芍15克,远志15克,泽泻15克,续断15克,元胡15克,地龙15克,木香15克,党参15克,郁金15克,细辛15克,柴胡15克,当归15克,桑寄生15克,人参15克,穿山甲15克,麦冬20克,熟地20克,独活15克,黄芪20克,女贞子15克,车前子20克,夏枯草15克,川芎15克。
[0075] 配制及服用方法:同例I。

Claims (2)

1.一种治疗卵巢癌的中药组合物,其特征是,由以下重量的中药制成: 半夏5 — 15克,莪术5 — 15克,白术5 — 15克,没药5 — 15克,杜仲5 — 15克,杏仁5 - 15克,赤芍5 — 15克,远志5 — 15克,泽泻5 — 15克,续断10 — 20克,元胡10 — 20克,地龙10 - 20克,木香10 - 20克,党参10 - 20克,郁金10 — 20克,细辛10 — 20克,柴胡10 — 20克,当归10 — 20克,桑寄生10 — 20克,人参10 — 20克,穿山甲10 — 20克,麦冬10 — 20克,熟地10 - 20克,独活10 — 20克,黄芪15 — 25克,女贞子15 — 25克,车前子15 - 25克,夏枯草15 - 25克,川芎15 — 25克。
2.根据权利要求1所述的治疗卵巢癌的中药组合物,其特征是,由以下重量的中药制成: 半夏10克,莪术10克,白术10克,没药10克,杜仲10克,杏仁10克,赤芍10克,远志10克,泽泻10克,续断15克,元胡15克,地龙15克,木香15克,党参15克,郁金15克,细辛15克,柴胡15克,当归15克,桑寄生15克,人参15克,穿山甲15克,麦冬15克,熟地15克,独活15克,黄芪20克,女贞子20克,车前子20克,夏枯草20克,川芎20克。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017048191A1 (en) * 2015-09-14 2017-03-23 Moleac Pte Ltd. Process for preparing herbal extracts
CN109432251A (zh) * 2018-10-16 2019-03-08 吴蓓莉 一种用于治疗卵巢癌的中药组合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020114854A1 (en) * 2001-02-21 2002-08-22 Ku Jeng Chinese herb medicine composition for cancer prophylaxis and therapy
CN103520659A (zh) * 2013-11-01 2014-01-22 汤曙光 一种治疗癌症的中药

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020114854A1 (en) * 2001-02-21 2002-08-22 Ku Jeng Chinese herb medicine composition for cancer prophylaxis and therapy
CN103520659A (zh) * 2013-11-01 2014-01-22 汤曙光 一种治疗癌症的中药

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张诗军等: "《肿瘤中医生物养生治疗学》", 31 July 2013, 广东科技出版社 *
黄志杰: "《中医抗癌古今验方精选》", 31 August 2009, 湖北科学技术出版社 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017048191A1 (en) * 2015-09-14 2017-03-23 Moleac Pte Ltd. Process for preparing herbal extracts
US10463707B2 (en) 2015-09-14 2019-11-05 Moleac Pte Ltd. Process for preparing herbal extracts
RU2723945C2 (ru) * 2015-09-14 2020-06-18 Молеак Пте Лтд. Способ получения вытяжек из трав
CN109432251A (zh) * 2018-10-16 2019-03-08 吴蓓莉 一种用于治疗卵巢癌的中药组合物

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