CN104350058A - 2-氨基-4-芳基噻唑化合物的酰胺及其盐 - Google Patents

2-氨基-4-芳基噻唑化合物的酰胺及其盐 Download PDF

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Publication number
CN104350058A
CN104350058A CN201380030184.XA CN201380030184A CN104350058A CN 104350058 A CN104350058 A CN 104350058A CN 201380030184 A CN201380030184 A CN 201380030184A CN 104350058 A CN104350058 A CN 104350058A
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CN
China
Prior art keywords
formula
compound
difluoro
trifluoromethyl
dimethyl
Prior art date
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Pending
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CN201380030184.XA
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English (en)
Chinese (zh)
Inventor
苏雷什·马哈德维·卡达姆
亚伯拉罕·托马斯
苏库马尔·辛哈
苏克尔斯·库马尔
拜平·帕索坦·坎萨格拉
萨钦·加维哈恩
桑迪普·班杜·坎达盖尔
谢利施·帕瓦斯
贾扬塔·普拉卡什奥·帕蒂尔
谢勒恩卓·巴达恩
巴维纳·米什拉
拉杰什·德维韦迪
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Ichnos Sciences SA
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Glenmark Pharmaceuticals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54193746&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN104350058(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glenmark Pharmaceuticals SA filed Critical Glenmark Pharmaceuticals SA
Publication of CN104350058A publication Critical patent/CN104350058A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN201380030184.XA 2012-06-08 2013-06-08 2-氨基-4-芳基噻唑化合物的酰胺及其盐 Pending CN104350058A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
IN1687MU2012 2012-06-08
IN1687/MUM/2012 2012-06-08
US201261665282P 2012-06-27 2012-06-27
US61/665,282 2012-06-27
IN3519/MUM/2012 2012-12-13
IN3519MU2012 2012-12-13
US201261748016P 2012-12-31 2012-12-31
US61/748,016 2012-12-31
PCT/IB2013/054703 WO2013183035A2 (en) 2012-06-08 2013-06-08 Amides of 2-amino-4-arylthiazole compounds and their salts

Publications (1)

Publication Number Publication Date
CN104350058A true CN104350058A (zh) 2015-02-11

Family

ID=54193746

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380030184.XA Pending CN104350058A (zh) 2012-06-08 2013-06-08 2-氨基-4-芳基噻唑化合物的酰胺及其盐

Country Status (22)

Country Link
US (1) US9458173B2 (https=)
EP (1) EP2858999B1 (https=)
JP (1) JP5989900B2 (https=)
KR (1) KR20150015488A (https=)
CN (1) CN104350058A (https=)
AP (1) AP3546A (https=)
AU (1) AU2013273118B2 (https=)
BR (1) BR112014029155A2 (https=)
CA (1) CA2873570C (https=)
CL (1) CL2014003317A1 (https=)
EA (1) EA031334B1 (https=)
HK (1) HK1207643A1 (https=)
IL (1) IL236084A0 (https=)
IN (1) IN2014MN02467A (https=)
MX (1) MX354014B (https=)
MY (1) MY165622A (https=)
NZ (1) NZ701721A (https=)
PE (1) PE20142306A1 (https=)
PH (1) PH12014502685B1 (https=)
SG (1) SG11201408093PA (https=)
WO (1) WO2013183035A2 (https=)
ZA (1) ZA201500082B (https=)

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CN114891003A (zh) * 2022-04-27 2022-08-12 成都施贝康生物医药科技有限公司 新型二氢嘧啶类化合物、中间体或盐及其制备方法和用途

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EA026235B1 (ru) 2012-06-08 2017-03-31 Джилид Сайэнс, Инк. Макроциклические ингибиторы вирусов flaviviridae
AR091279A1 (es) 2012-06-08 2015-01-21 Gilead Sciences Inc Inhibidores macrociclicos de virus flaviviridae
EP3010489A1 (en) 2013-06-20 2016-04-27 Glenmark Pharmaceuticals S.A. Nanoparticulate formulation comprising a trpa1 antagonist
EP3180345B1 (en) * 2014-08-11 2018-10-10 Hydra Biosciences, Inc. Thieno- and furo[2,3-d]pyrimidine-2,4[1h,3h]-dione derivatives as trpc5 modulators for the treatment of neuropsychiatric disorders
WO2016042501A1 (en) * 2014-09-16 2016-03-24 Glenmark Pharmaceuticals S.A. Trpa1 antagonist for the treatment of pain associated to diabetic neuropathic pain
TW202321229A (zh) 2021-08-18 2023-06-01 美商富曼西公司 殺真菌的取代的雜環化合物

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ES2193839B1 (es) * 2001-06-22 2005-02-16 Almirall Prodesfarma, S.A. Nuevos derivados de 6-fenildihidropirrolpirimidindiona.
WO2004014916A1 (en) * 2002-08-13 2004-02-19 Warner-Lambert Company Llc Pyrimidine fused bicyclic metalloproteinase inhibitors
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US20070105920A1 (en) 2005-11-08 2007-05-10 Akzo Nobel N.V. 2-(Benzimidazol-1-Yl)-N-(4-phenylthiazol-2-yl) acetamide derivatives
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114891003A (zh) * 2022-04-27 2022-08-12 成都施贝康生物医药科技有限公司 新型二氢嘧啶类化合物、中间体或盐及其制备方法和用途
CN114891003B (zh) * 2022-04-27 2023-10-13 成都施贝康生物医药科技有限公司 新型二氢嘧啶类化合物、中间体或盐及其制备方法和用途

Also Published As

Publication number Publication date
BR112014029155A2 (pt) 2017-06-27
EA201492054A1 (ru) 2016-08-31
MX354014B (es) 2018-02-08
PH12014502685A1 (en) 2015-01-26
NZ701721A (en) 2016-03-31
WO2013183035A3 (en) 2014-02-27
SG11201408093PA (en) 2015-01-29
US9458173B2 (en) 2016-10-04
AU2013273118B2 (en) 2015-11-05
MY165622A (en) 2018-04-18
EA031334B1 (ru) 2018-12-28
JP2015520183A (ja) 2015-07-16
AU2013273118A1 (en) 2014-11-27
ZA201500082B (en) 2015-12-23
EP2858999A2 (en) 2015-04-15
EP2858999B1 (en) 2017-05-10
IN2014MN02467A (https=) 2015-07-10
HK1207643A1 (en) 2016-02-05
MX2014014482A (es) 2015-06-05
KR20150015488A (ko) 2015-02-10
CA2873570C (en) 2016-11-01
IL236084A0 (en) 2015-02-01
CL2014003317A1 (es) 2015-02-13
AP3546A (en) 2016-01-14
PH12014502685B1 (en) 2015-01-26
US20150111038A1 (en) 2015-04-23
AP2014008076A0 (en) 2014-11-30
PE20142306A1 (es) 2015-01-16
CA2873570A1 (en) 2013-12-12
WO2013183035A2 (en) 2013-12-12
JP5989900B2 (ja) 2016-09-07

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Effective date of abandoning: 20180126