CN104306476A - Traditional Chinese medicine composition for treating dysmenorrhea and application of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating dysmenorrhea and application of traditional Chinese medicine composition Download PDF

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CN104306476A
CN104306476A CN201410632044.6A CN201410632044A CN104306476A CN 104306476 A CN104306476 A CN 104306476A CN 201410632044 A CN201410632044 A CN 201410632044A CN 104306476 A CN104306476 A CN 104306476A
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chinese medicine
medicine composition
dysmenorrhea
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崔银方
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Abstract

The invention discloses a traditional Chinese medicine composition for treating dysmenorrhea, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the raw medicinal materials of cortex moutan, excrementum pteropi, angelica sinensis, rhizoma corydalis, ligusticum wallichii, red peony root, fennel, liquorice, lumbricus, euonymus fortunei, fructus schizandrae, Clematis chrysocoma, cytisus and mulberry. The traditional Chinese medicine composition is reasonably mixed, can achieve the synergistic effect, has the functions of improving collateral circulation, regulating qi, activating blood and removing stasis to relieve pain, can treat the dysmenorrhea fundamentally, is outstanding in effect and is convenient to use; the daily oral administration amount is small, and medicinal materials are readily available.

Description

A kind of Chinese medicine composition and application thereof for the treatment of dysmenorrhea
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine composition for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea (dysmenorrhea) refers to painful menstrual periods, and normal in spastic, concentrate on hypogastric region, other symptoms comprise headache, weak, dizzy, nausea,vomiting,diarrhea, lumbago and skelalgia.It is the very common disease of young woman.Primary dysmenorrhea is without obvious pelvic cavity organic disease.Age is the key factor during dysmenorrhea occurs.At the first few months of menarche, dysmenorrhea occurs few, incidence rate raises rapidly subsequently, reaches peak (82%) when 16 ~ 18 years old, 30-35 year decline gradually later, in childbearing age middle stable about 40%, later lower, maintain 20% when 50 years old.The beginning of sexual life, can reduce the incidence rate of dysmenorrhea.Follow up survey 5 annual bearing of Sweden 19 years old young woman is shown, drops to 67% to dysmenorrhea incidence rate when 24 years old from 72%.The order of severity also declines.Dysmenorrhea just drastically influence health and the daily life of women.
Mostly western medicine dysmenorrhea is lenitive symptom, can not from more this is treated, and side effect is larger.The traditional Chinese medical science is thought, dysmenorrhea main pathogenesis is volt in pathogen, menses virtual loss, causes the QI-blood circulation of uterus not smooth, " stagnation of QI and blood may bring about pain "; Or uterus loses in moistening foster, " not Rong Ze pain ", therefore causes dysmenorrhea.Treatment dysmenorrhea, the opinion that the traditional Chinese medical science has it original can rich experience.
Summary of the invention
The object of this invention is to provide a kind of instant effect, good effect, taking convenience, the Chinese medicine composition for the treatment of dysmenorrhea that has no side effect.
For achieving the above object, the present invention by the following technical solutions.
Treat a Chinese medicine composition for dysmenorrhea, it is obtained by following raw material medicine: Cortex Moutan 1-20 part, Oletum Trogopterori 1-20 part, Radix Angelicae Sinensis 1-20 part, Rhizoma Corydalis 1-10 part, Rhizoma Chuanxiong 1-30 part, Radix Paeoniae Rubra 1-15 part, Fructus Foeniculi 1-10 part, Radix Glycyrrhizae 1-10 part, Pheretima 1-10 part, Euonymus fortunei 1-20 part, Fructus Schisandrae Chinensis 1-10 part, Herba Clematidis loureirianae 1-20 part, Flos Caraganae Sinicae 1-20 part, Fructus Mori 1-20 part.
The present invention treats the Chinese medicine composition of dysmenorrhea, is preferably further obtained by following raw material medicine: above-mentioned Cortex Moutan 1-15 part, Oletum Trogopterori 1-15 part, Radix Angelicae Sinensis 1-15 part, Rhizoma Corydalis 1-9 part, Rhizoma Chuanxiong 1-20 part, Radix Paeoniae Rubra 1-14 part, Fructus Foeniculi 1-9 part, Radix Glycyrrhizae 1-9 part, Pheretima 1-9 part, Euonymus fortunei 1-15 part, Fructus Schisandrae Chinensis 1-9 part, Herba Clematidis loureirianae 1-18 part, Flos Caraganae Sinicae 1-18 part, Fructus Mori 1-18 part.
Further, the Chinese medicine composition of above-mentioned treatment dysmenorrhea, it is obtained by following raw material medicine: Cortex Moutan 5-12 part, Oletum Trogopterori 6-13 part, Radix Angelicae Sinensis 8-12 part, Rhizoma Corydalis 2-8 part, Rhizoma Chuanxiong 6-17 part, Radix Paeoniae Rubra 2-12 part, Fructus Foeniculi 3-8 part, Radix Glycyrrhizae 3-8 part, Pheretima 2-8 part, Euonymus fortunei 5-13 part, Fructus Schisandrae Chinensis 4-8 part, Herba Clematidis loureirianae 9-15 part, Flos Caraganae Sinicae 8-16 part, Fructus Mori 10-17 part.
Most preferably, the prescription proportioning filtering out three effects best according to effect is as follows:
(1) Cortex Moutan 6 parts, Oletum Trogopterori 7 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Corydalis 3 parts, Rhizoma Chuanxiong 10 parts, Radix Paeoniae Rubra 10 parts, Fructus Foeniculi 6 parts, 4 parts, Radix Glycyrrhizae, Pheretima 3 parts, Euonymus fortunei 9 parts, Fructus Schisandrae Chinensis 6 parts, Herba Clematidis loureirianae 11 parts, Flos Caraganae Sinicae 12 parts, 13 parts, Fructus Mori.
(2) Cortex Moutan 8 parts, Oletum Trogopterori 9 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Corydalis 6 parts, Rhizoma Chuanxiong 13 parts, Radix Paeoniae Rubra 11 parts, Fructus Foeniculi 7 parts, 5 parts, Radix Glycyrrhizae, Pheretima 6 parts, Euonymus fortunei 10 parts, Fructus Schisandrae Chinensis 7 parts, Herba Clematidis loureirianae 13 parts, Flos Caraganae Sinicae 15 parts, 15 parts, Fructus Mori.
(3) Cortex Moutan 10 parts, Oletum Trogopterori 10 parts, Radix Angelicae Sinensis 11 parts, Rhizoma Corydalis 7 parts, Rhizoma Chuanxiong 12 parts, Radix Paeoniae Rubra 12 parts, Fructus Foeniculi 8 parts, 6 parts, Radix Glycyrrhizae, Pheretima 7 parts, Euonymus fortunei 13 parts, Fructus Schisandrae Chinensis 8 parts, Herba Clematidis loureirianae 14 parts, Flos Caraganae Sinicae 16 parts, 16 parts, Fructus Mori.
This Chinese medicine composition can make Chinese medicine preparation by following steps: accurately take by Chinese prescription of the present invention: Cortex Moutan, Oletum Trogopterori, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Fructus Foeniculi, Radix Glycyrrhizae, Pheretima, Euonymus fortunei, Fructus Schisandrae Chinensis, Herba Clematidis loureirianae, Flos Caraganae Sinicae, Fructus Mori, pulverize respectively, mix; Add the purified water of 8 times of weight, backflow decoction 2 hours, filter to get filtrate a; In filtering residue, add the purified water of initial medical material 3 times of weight, backflow decoction 2 hours, filter to get filtrate b; In filtering residue, add the purified water of initial medical material 3 times of weight, backflow decoction 1 hour, filter to get filtrate c; By filtrate a, b, c mix, carry out concentrating under reduced pressure, until the relative density of mixed liquor is 1.15-1.23(70-75 DEG C of surveys) time stop concentrate, obtain the concentrated liquid of tradition Chinese medicine decoction.Add other adjuvants and further the concentrated liquid of tradition Chinese medicine is made oral liquid.
The each crude drug taken by prescription can be pulverized by those skilled in the art, adds adjuvant and makes the finished product preparation such as tablet, capsule, granule.
Found by clinical application research, the pharmaceutical composition having above-mentioned Chinese crude drug to be prepared from is evident in efficacy in treatment dysmenorrhea, and therefore second object of the present invention is to provide a kind of new medical use, and namely said medicine is in the application of preparation treatment dysmenorrhea medicine.
According to traditional Chinese medical science Chinese medicine Historical Data Data About, above-mentioned Chinese crude drug has following pharmacologically active and function cures mainly:
Cortex Moutan, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Oletum Trogopterori, promoting blood circulation to remove blood stasis, parch to black stops blooding.Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis.
Radix Angelicae Sinensis, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Rhizoma Corydalis, invigorates blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Rhizoma Chuanxiong, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Radix Paeoniae Rubra, clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Fructus Foeniculi, the kidney warming warms up liver; Promoting the circulation of QI to relieve pain; Stomach function regulating.Main colic of cold type stomachache; The testis swelling and hanging down of either of the testes; Coldness and pain in the epigastrium; Lack of appetite and vomiting; Hypochondriac pain; Lumbago due to renal deficiency; Dysmenorrhea.
Radix Glycyrrhizae, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Pheretima, clear gesture relieving convulsion; Suppressing the hyperactive liver to relieve the wind syndrome; Dredge the meridian passage; To relieving asthma diuresis.Main calentura heating is mad dry; Infantile convulsion is twitched; Headache due to hyperactivity of liver-YANG; Apoplectic hemiplegia; Rheumatic arthralgia; Dyspnea and cough due to lung-heat; Urinary obstruction.
Euonymus fortunei, invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood flow to regulate menstruation.Main lumbago due to renal deficiency; Chronic diarrhea; Rheumatic arthralgia; Have through uncomfortable; Traumatic injury.
Fructus Schisandrae Chinensis, restrains astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Herba Clematidis loureirianae, clearing away heat and promoting diuresis; Relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation to restore menstrual flow; Blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness.Main dysuria; Edema; Damp-heat gonorrhoea; Rheumatic arthralgia; Traumatic injury; Scorching on wind-fire; Eye red pain; Amenorrhea; Mange.
Flos Caraganae Sinicae, YIN nourishing, and blood, spleen invigorating.Control consumptive fever cough, the dizzy soreness of waist, women's deficiency of vital energy leucorrhea, infantile malnutrition, acute mastitis, injury from falling down.
Fructus Mori, YIN nourishing of enriching blood, promotes the production of body fluid and moisturizes.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
Pharmaceutical composition compatibility of the present invention is reasonable, plays synergistic function, has the function of soothing the channels and quicking the network vessels, vital energy regualting and blood circulation-promoting, eliminating stasis to stop pain, fundamentally can treat dysmenorrhea, Be very effective, easy to use; Every day, dosage was little, and crude drug source is extensive.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is made further research, but the present invention is not limited to these embodiments.
the preparation of embodiment 1 Chinese medicine decoction of the present invention
Prescription: Cortex Moutan 6g, Oletum Trogopterori 7g, Radix Angelicae Sinensis 9g, Rhizoma Corydalis 3g, Rhizoma Chuanxiong 10g, Radix Paeoniae Rubra 10g, Fructus Foeniculi 6g, Radix Glycyrrhizae 4g, Pheretima 3g, Euonymus fortunei 9g, Fructus Schisandrae Chinensis 6g, Herba Clematidis loureirianae 11g, Flos Caraganae Sinicae 12g, Fructus Mori 13g.
Preparation method: accurately take Cortex Moutan, Oletum Trogopterori, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Fructus Foeniculi, Radix Glycyrrhizae, Pheretima, Euonymus fortunei, Fructus Schisandrae Chinensis, Herba Clematidis loureirianae, Flos Caraganae Sinicae, Fructus Mori by Chinese prescription of the present invention, pulverize respectively, mix; Add the purified water of 8 times of weight, backflow decoction 2 hours, filter to get filtrate a; In filtering residue, add the purified water of initial medical material 3 times of weight, backflow decoction 2 hours, filter to get filtrate b; In filtering residue, add the purified water of initial medical material 3 times of weight, backflow decoction 1 hour, filter to get filtrate c; By filtrate a, b, c mix, carry out concentrating under reduced pressure, until the relative density of mixed liquor is 1.15-1.23(70-75 DEG C of surveys) time stop concentrate, obtain Chinese medicine decoction.
the preparation of embodiment 2 Chinese medicine decoction of the present invention
Prescription: Cortex Moutan 8g, Oletum Trogopterori 9g, Radix Angelicae Sinensis 10g, Rhizoma Corydalis 6g, Rhizoma Chuanxiong 13g, Radix Paeoniae Rubra 11g, Fructus Foeniculi 7g, Radix Glycyrrhizae 5g, Pheretima 6g, Euonymus fortunei 10g, Fructus Schisandrae Chinensis 7g, Herba Clematidis loureirianae 13g, Flos Caraganae Sinicae 15g, Fructus Mori 15g.
Preparation method is with embodiment 1.
the preparation of embodiment 3 Chinese medicine decoction of the present invention
Prescription: Cortex Moutan 10g, Oletum Trogopterori 10g, Radix Angelicae Sinensis 11g, Rhizoma Corydalis 7g, Rhizoma Chuanxiong 12g, Radix Paeoniae Rubra 12g, Fructus Foeniculi 8g, Radix Glycyrrhizae 6g, Pheretima 7g, Euonymus fortunei 13g, Fructus Schisandrae Chinensis 8g, Herba Clematidis loureirianae 14g, Flos Caraganae Sinicae 16g, Fructus Mori 16g.
Preparation method is with embodiment 1.
the animal toxicity test of embodiment 4 medicine decoction of the present invention
(1), acute toxicity test
1, test drug: medicine decoction obtained by the embodiment of the present invention 3.Test animal used: regular grade NIH mice, body weight 21g ± 6g, male and female half and half, female mice is all without pregnant;
2, apply mice to carry out acute toxicity testing and show: the decoction of mouse stomach embodiment 3, under 750g/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none dead mouse, and overall health of patients, diet, take the photograph water, urine and body weight increase all normal, judges that Chinese medicine composition of the present invention is to the nontoxic level in the true border of chmice acute Oral toxicity.
(2), long-term toxicity test for animals
1, medicine: medicine decoction obtained by the embodiment of the present invention 3.
2, animal: regular grade SD rat, original body mass 217 ± 6g, male and female half and half, female rats is all without pregnant.
3, method and result:
(1) 3 kind of Chinese medicine decoction: be divided into high, medium and low three dosage groups, per weight dosage is respectively 180,60,20 times of patient's dose;
(2) experimental mouse is divided into 4 groups at random, wherein the decoction of 3 groups of difference gavages, 3 kinds of three dosage, remains one group of gavage normal saline (40 times of patient's dose); All 4 groups of all continuous gavages 180 days, observe animal general toxic reaction and the order of severity, check each position, and carry out hematology, the pathological examination of the main organs such as ALT, BUN and the heart, liver, spleen, lung, kidney, stomach after execution by rule of operation;
(3) through long-term feeding, all there is not toxic reaction in 4 groups of rats.Physically well develop.Macroscopic appearance and main organs no abnormality seen.Peripheral hemogram and Serum ALT, BUN compare with matched group and change without pathologic.The all not significant changes such as the pathological replacement heart, liver, spleen, lung, kidney, stomach, therefore, think through proved by pathology, 3 kinds of Chinese medicine decoction show without chronic toxicity animal.
By above two toxicity tests, prove that the Chinese medicine decoction that the present invention makes by embodiment 3 is safe, have no side effect, can be taken by patient.
embodiment 5 clinical practice effectiveness study
(1) physical data
Screen 100 menalgia patients, show as menstrual period or lower abdomen pain before and after row, pain and waist sacrum, even faint, in periodical attack.Age is between 17-36.
(2) Therapeutic Method
Take the decoction that embodiment 3 is obtained, potion, was divided into and sooner or later took for 2 times every day.It within 10 days, is 1 course for the treatment of.Medicine time is that each menstrual cycle takes 1 course for the treatment of, second day that terminates from menstruation.
(3) efficacy assessment standard
Cure: pain disappears, and continuous 3 menstrual cycle have no recurrence.
Take a turn for the better: pain relief or pain disappear, but can not maintain more than 3 months.
Do not heal: pain has no improvement.
(4) therapeutic effect
Take a course for the treatment of, pay a return visit after 3 months, 100 cure for there being 85 people in patient, and 13 people take a turn for the better, and 2 people are not healed.Total effective rate reaches 98%, cure rate 85%.
Exemplary embodiments:
Zhang, female, 20 years old, lower abdomen hurt like hell was felt in menstruation often, and have pendant pain, the soreness of waist, trick is ice-cold, often needs transfusion to carry out alleviating pain.After taking 1 course for the treatment of of medicine of the present invention, pain obviously alleviates, then after continuing to take two courses for the treatment of, above-mentioned symptom disappears, and has no recurrence after 3 months.

Claims (9)

1. treat a Chinese medicine composition for dysmenorrhea, it is characterized in that being obtained by following raw material medicine: Cortex Moutan 1-20 part, Oletum Trogopterori 1-20 part, Radix Angelicae Sinensis 1-20 part, Rhizoma Corydalis 1-10 part, Rhizoma Chuanxiong 1-30 part, Radix Paeoniae Rubra 1-15 part, Fructus Foeniculi 1-10 part, Radix Glycyrrhizae 1-10 part, Pheretima 1-10 part, Euonymus fortunei 1-20 part, Fructus Schisandrae Chinensis 1-10 part, Herba Clematidis loureirianae 1-20 part, Flos Caraganae Sinicae 1-20 part, Fructus Mori 1-20 part.
2. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 1, is characterized in that being obtained by following raw material medicine: above-mentioned Cortex Moutan 1-15 part, Oletum Trogopterori 1-15 part, Radix Angelicae Sinensis 1-15 part, Rhizoma Corydalis 1-9 part, Rhizoma Chuanxiong 1-20 part, Radix Paeoniae Rubra 1-14 part, Fructus Foeniculi 1-9 part, Radix Glycyrrhizae 1-9 part, Pheretima 1-9 part, Euonymus fortunei 1-15 part, Fructus Schisandrae Chinensis 1-9 part, Herba Clematidis loureirianae 1-18 part, Flos Caraganae Sinicae 1-18 part, Fructus Mori 1-18 part.
3. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 2, is characterized in that being obtained by following raw material medicine: Cortex Moutan 5-12 part, Oletum Trogopterori 6-13 part, Radix Angelicae Sinensis 8-12 part, Rhizoma Corydalis 2-8 part, Rhizoma Chuanxiong 6-17 part, Radix Paeoniae Rubra 2-12 part, Fructus Foeniculi 3-8 part, Radix Glycyrrhizae 3-8 part, Pheretima 2-8 part, Euonymus fortunei 5-13 part, Fructus Schisandrae Chinensis 4-8 part, Herba Clematidis loureirianae 9-15 part, Flos Caraganae Sinicae 8-16 part, Fructus Mori 10-17 part.
4. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 3, is characterized in that being obtained by following raw material medicine: Cortex Moutan 6 parts, Oletum Trogopterori 7 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Corydalis 3 parts, Rhizoma Chuanxiong 10 parts, Radix Paeoniae Rubra 10 parts, Fructus Foeniculi 6 parts, 4 parts, Radix Glycyrrhizae, Pheretima 3 parts, Euonymus fortunei 9 parts, Fructus Schisandrae Chinensis 6 parts, Herba Clematidis loureirianae 11 parts, Flos Caraganae Sinicae 12 parts, 13 parts, Fructus Mori.
5. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 3, is characterized in that being obtained by following raw material medicine: Cortex Moutan 8 parts, Oletum Trogopterori 9 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Corydalis 6 parts, Rhizoma Chuanxiong 13 parts, Radix Paeoniae Rubra 11 parts, Fructus Foeniculi 7 parts, 5 parts, Radix Glycyrrhizae, Pheretima 6 parts, Euonymus fortunei 10 parts, Fructus Schisandrae Chinensis 7 parts, Herba Clematidis loureirianae 13 parts, Flos Caraganae Sinicae 15 parts, 15 parts, Fructus Mori.
6. the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 3, is characterized in that being obtained by following raw material medicine: Cortex Moutan 10 parts, Oletum Trogopterori 10 parts, Radix Angelicae Sinensis 11 parts, Rhizoma Corydalis 7 parts, Rhizoma Chuanxiong 12 parts, Radix Paeoniae Rubra 12 parts, Fructus Foeniculi 8 parts, 6 parts, Radix Glycyrrhizae, Pheretima 7 parts, Euonymus fortunei 13 parts, Fructus Schisandrae Chinensis 8 parts, Herba Clematidis loureirianae 14 parts, Flos Caraganae Sinicae 16 parts, 16 parts, Fructus Mori.
7. the preparation method of the Chinese medicine composition of the treatment dysmenorrhea as described in as arbitrary in claim 1-6, it is characterized in that comprising the following steps: accurately take Cortex Moutan, Oletum Trogopterori, Radix Angelicae Sinensis, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Fructus Foeniculi, Radix Glycyrrhizae, Pheretima, Euonymus fortunei, Fructus Schisandrae Chinensis, Herba Clematidis loureirianae, Flos Caraganae Sinicae, Fructus Mori by this prescription, pulverize respectively, mix; Add the purified water of 8 times of weight, backflow decoction 2 hours, filter to get filtrate a; In filtering residue, add the purified water of initial medical material 3 times of weight, backflow decoction 2 hours, filter to get filtrate b; In filtering residue, add the purified water of initial medical material 3 times of weight, backflow decoction 1 hour, filter to get filtrate c; Filtrate a, b, c are mixed, carries out concentrating under reduced pressure, until recording at 70-75 DEG C when relative density is 1.15-1.23 of mixed liquor stops concentrating, obtain the concentrated liquid of tradition Chinese medicine decoction.
8. the preparation method of the Chinese medicine composition for the treatment of dysmenorrhea as claimed in claim 7, is characterized in that: described Chinese medicine composition can also make oral liquid, tablet, capsule, granule.
9. the arbitrary described Chinese medicine composition of claim 1-6 is in the application of preparation treatment dysmenorrhea medicine.
CN201410632044.6A 2014-11-12 2014-11-12 Traditional Chinese medicine composition for treating dysmenorrhea and application of traditional Chinese medicine composition Pending CN104306476A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101028401A (en) * 2006-12-28 2007-09-05 王玉秀 Oral Chinese medicine for treating difficult menstruation
CN101642518A (en) * 2009-05-31 2010-02-10 李跃 Plaster for treating dysmenorrhea
CN101884752A (en) * 2010-08-02 2010-11-17 郑孔吉 Chinese medicinal preparation for navel plaster and preparation method thereof
CN102488875A (en) * 2011-12-15 2012-06-13 于燕 Traditional Chinese medicine for treating acquired dysmenorrhea
CN103859373A (en) * 2012-12-10 2014-06-18 天津红日药业股份有限公司 Formula and preparation method of life cultivation and health preservation food helpful for preserving health during menstrual period

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101028401A (en) * 2006-12-28 2007-09-05 王玉秀 Oral Chinese medicine for treating difficult menstruation
CN101642518A (en) * 2009-05-31 2010-02-10 李跃 Plaster for treating dysmenorrhea
CN101884752A (en) * 2010-08-02 2010-11-17 郑孔吉 Chinese medicinal preparation for navel plaster and preparation method thereof
CN102488875A (en) * 2011-12-15 2012-06-13 于燕 Traditional Chinese medicine for treating acquired dysmenorrhea
CN103859373A (en) * 2012-12-10 2014-06-18 天津红日药业股份有限公司 Formula and preparation method of life cultivation and health preservation food helpful for preserving health during menstrual period

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Application publication date: 20150128