CN104274907B - A kind of defibrillator - Google Patents
A kind of defibrillator Download PDFInfo
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- CN104274907B CN104274907B CN201410482471.0A CN201410482471A CN104274907B CN 104274907 B CN104274907 B CN 104274907B CN 201410482471 A CN201410482471 A CN 201410482471A CN 104274907 B CN104274907 B CN 104274907B
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Abstract
The invention discloses a kind of defibrillator, relate to electric defibrillation technical field, this instrument first passes through defibrillation electrode and obtains patient's electrocardiosignal, after amplified filtering, it is digitized gathering, afterwards the one-dimensional electrocardiogram (ECG) data collected is mapped on two dimensional surface after the time delay of certain time, form and distribution by two-dimensional map scatter diagram calculate phase space scale parameter again, width and the uniformity coefficient of scatterplot data distribution including the distribution of scatterplot data, method finally by mathematical modeling sets up multi-parameter prediction function model, calculate the prediction successful index of defibrillation.The beneficial effects of the present invention is: be analyzed processing to the electrocardiosignal gathering patient, calculate the value of phase space yardstick, output module continues pressing according to phase space yardstick output suggestion defibrillation or suggestion, suggestion can be provided for medical personnel at short notice, not interfere with the treatment of the patient that quivered in room.
Description
Technical field
The present invention relates to a kind of electric defibrillation technical field, particularly to a kind of defibrillator.
Background technology
Electric defibrillation is an important link during CPR (CPR), and it refers to a certain amount of electricity
Stream impact heart is so that ventricular fibrillation terminates.The success or not direct relation of electric defibrillation ventricular fibrillation patient
Survival, be the treatment maximally efficient method of ventricular fibrillation.Research shows, occurs that ventricular fibrillation is suffered from by analysis
The electrocardiosignal of person, grasp patient heart condition that can be real-time, and whether can be successful to electric defibrillation this moment
Make effective judgement and prediction.The prediction of this defibrillation usefulness can greatly reduce unnecessary electric defibrillation,
Only just carry out defibrillation when some index of electrocardiosignal reaches to expect threshold value, reduce electric current to patient's cardiac muscle
Damage.
At present, it was predicted that the successful algorithm of electric defibrillation emerges in an endless stream, its method be mainly based upon amplitude, frequency with
And amplitude-frequency analysis realizes the prediction of defibrillation usefulness.But the accuracy rate of most of algorithms prediction is the highest, analyzes
Required signal length is longer, and these all can affect the treatment of the patient that quivers room.
Summary of the invention
In view of this, the technical problem to be solved in the present invention is to provide a kind of defibrillator, to the electrocardio letter gathered
Number process, suggestion defibrillation or suggestion can be provided to continue the suggestion of pressing for medical personnel in short-term.
The present invention is by the techniques below means above-mentioned technical problem of solution:
The present invention provides a kind of defibrillator, including ecg signal acquiring module, is used for gathering patient's electrocardiogram (ECG) data；
Electrocardiosignal time delay module, for choosing the electrocardiogram (ECG) data of 0.1s～10s and electrocardiogram (ECG) data being carried out time delay；The heart
Electricity data processing module, for the electrocardiogram (ECG) data after time delay being carried out two dimension Scatter plot, the 0.1s chosen～
The electrocardiogram (ECG) data of 10s is abscissa, and the electrocardiogram (ECG) data after time delay is that ordinate draws two dimension scatter diagram, is dissipated
The peak width Width of point data distribution and standard B of evaluation scatterplot data distributing homogeneity, by scatterplot data
The peak width Width of distribution and standard B of evaluation scatterplot data distributing homogeneity carry out mathematical modeling, calculate
Go out phase space yardstick PSS；Output module, exports prompting for the value according to described phase space yardstick PSS
Suggestion, described ecg signal acquiring module, electrocardiosignal time delay module, electrocardiogram (ECG) data processing module and output mould
Block is sequentially connected with.
Further, the processing procedure of described electrocardiogram (ECG) data processing module is: be analyzed described two dimension scatter diagram,
Calculate each scatterplot distance d to straight line x=y, find distance d, make the distance sample point less than d account for all
The 95% of data point, and with 1.5d as boundary, get rid of the distance value exceptional data point more than 1.5d, calculate straight
Distance maximum in line x=y two side data is also added the peak width Width obtaining the distribution of scatterplot data:
Width=maxup+maxdown, wherein, Width is the peak width of scatterplot data distribution, maxupDissipate for top
Put away from straight line x=y apart from farthest numerical value, maxdownFor bottom scatterplot away from straight line x=y apart from farthest numerical value；
Do line of demarcation with Width/2 for standard, calculate the data point sum N that line of demarcation is upper and lower, with on line of demarcation
Under the difference counted as standard B:B=evaluating scatterplot data distributing homogeneity | Nup-Ndown|, wherein, Nup
Represent the data point sum on top, line of demarcation, NdownRepresent the data point sum of bottom, line of demarcation；
Further, described electrocardiogram (ECG) data processing module calculates the formula of phase space yardstick PSS: PSS=K*Width
-Y*B, wherein, K is scatterplot width weight coefficient, and Y is the weight coefficient of uniformity coefficient, and Width is scatterplot
The width of data scatter, B is the standard evaluating scatterplot data distributing homogeneity；
Further, described electrocardiogram (ECG) data processing module calculates the formula of phase space yardstick PSS: PSS=10*
Width-0.0004*B, wherein, Width is the peak width of scatterplot data distribution, and B is for evaluating scatterplot number
Standard according to distributing homogeneity；
Further, when the value of the described phase space yardstick PSS calculated is more than or equal to 0.45, described defeated
Go out module output prompting suggestion defibrillation, when described phase space yardstick PSS value is less than 0.45, described output mould
Block output suggestion continues pressing.
Beneficial effects of the present invention:
The defibrillator of the present invention, is analyzed processing to the electrocardiosignal gathering patient, calculates phase space chi
The value of degree, output module continues pressing according to phase space yardstick output suggestion defibrillation or suggestion, can be in the short time
In provide suggestion for medical personnel, do not interfere with the treatment of the patient that quivered in room.
Accompanying drawing explanation
The invention will be further described with embodiment below in conjunction with the accompanying drawings.
Fig. 1 is the workflow diagram that the present invention calculates the method for electrocardiosignal phase place yardstick；
Fig. 2 is the two-dimentional scatter diagram that the present invention calculates the method for electrocardiosignal phase place yardstick；
Fig. 3 is that the present invention is by calculating method prediction defibrillation success and the prediction defibrillation of electrocardiosignal phase place yardstick
Failed schematic diagram；
Fig. 4 is the structural representation of the defibrillator of the present invention.
Detailed description of the invention
Below with reference to accompanying drawing, the present invention is described in detail, as shown in Figure 1:
The method calculating electrocardiosignal phase space yardstick of the present invention, comprises the following steps:
Step one: gather ecg signal data, obtains the electrocardiosignal of patient by defibrillation electrode, and by band
Bandpass filter pre-processes, and bandpass filter frequency range is 2Hz～48Hz.
Step 2: select the electrocardiogram (ECG) data image of 0.1s～10s to be analyzed with rectangular window before defibrillation, will choose
Signal carry out time delay τ after, and paint as ordinate of orthogonal axes using original signal as transverse axis coordinate, the signal after time delay
System two dimension scatter diagram, is mapped to one-dimensional electrocardiogram (ECG) data on two dimensional surface, wherein τ=3ms.
Step 3: as in figure 2 it is shown, two dimension scatter diagram is analyzed, calculate each scatterplot to straight line x=y's
Distance, finds distance d, makes the distance sample point less than d account for the 95% of all data points, and with 1.5d as boundary
Limit, by distance value getting rid of a little more than 1.5d, the exclude point in Fig. 2 needs to get rid of, distance value
More than 1.5d is a little exceptional data point.Calculate the distance maximum in straight line x=y two side data phase
Add the peak width Width, Width=max obtaining the distribution of scatterplot dataup+maxdown, wherein, Width table
Show the peak width that scatterplot data are distributed, maxupFor top scatterplot away from straight line x=y apart from farthest numerical value, maxdown
For bottom scatterplot away from straight line x=y apart from farthest numerical value.Do line of demarcation with Width/2 for standard, calculate boundary
The data point sum N that line is upper and lower, the difference counted up and down using line of demarcation is as evaluating scatterplot data distributing homogeneity
Standard B:B=| Nup-Ndown|, wherein NupRepresent the data point sum on top, line of demarcation, NdownRepresent boundary
The data point sum of line bottom.
Step 4: the comprehensive peak width Width analyzing the distribution of scatterplot data and data are evenly distributed degree B
Founding mathematical models, calculating is for predicting the phase space yardstick PSS of defibrillation usefulness:
PSS=K*Width Y*B
Wherein, K is scatterplot width weight coefficient, and Y is the weight coefficient of uniformity coefficient.Sample rate is fixed as 300Hz
Time, K value 10, Y changes adjustment according to analyzing data length, when taking 0.5 second data and being analyzed,
Y value 0.0004.
Obtaining through substantial amounts of experiment: K value is fixed as 10, and B value is fixed as 0.0004, sample rate is not solid
Fixed, the result calculated is not had too much influence, it may be assumed that
PSS=10*Width 0.0004*B.
Step 5: according to phase space yardstick PSS, obtains predicting the successful probability of defibrillation.As it is shown on figure 3,
2s electrocardiosignal a data remove and quiver in () figure before, is calculated PSS=0.48 according to above-mentioned steps, and defibrillation becomes
Merit, before in (b) figure, data remove and quiver, 2s electrocardiosignal, is calculated PSS=0.41 according to above-mentioned steps, removes
Quiver unsuccessfully, it is not recommended that defibrillation in practical operation.When PSS threshold value is set as 0.45, defibrillation sensitivity reaches
To 71.30%, specifically reach 71.57%.When PSS is more than or equal to 0.45, it was predicted that defibrillation can have bigger
Success rate, on the contrary it is the biggest to be less than 0.45 failed possibility of defibrillation, it is not recommended that defibrillation.Ordinary circumstance is by PSS
Threshold value is set as 0.45, PSS can also as the case may be and need be adjusted.
In order to prove that the present invention predicts that the successful method of defibrillation is better than additive method and has carried out contrast experiment, by with
416 defibrillation results of 214 cardiac arrest patients are analyzed by different methods, it was predicted that defibrillation is successful
Probability.The method used includes that the method (PSS) of the present invention, amplitude area compose (AMSA), signal integration
(SIGINT), intermediate value slope (MS) and power spectrumanalysis (PSA).The parameter knot that different methods is obtained
Fruit compares, and the parameter compared includes: under receiver operating characteristic curve, area AUC, sensitivity S en are
Specific Spe, positive prediction rate PPV, negative predictive rate NPV and accuracy rate Accuracy when 85%, as
Shown in table 1.Wherein, it was predicted that defibrillation successful probability key parameter is area under receiver operating characteristic curve
AUC and accuracy rate Accuracy.Result shows, adopts the recipient's operating characteristics being obtained by the present invention bent
Under line, area AUC and accuracy rate Accuracy are above other several methods, so the method using the present invention
It is better than other existing method.
| Method | AUC | Sen/Spe [%] | PPV/NPV [%] | Accuracy [%] |
| PSS | 0.802 | 84.26/56.86 | 40.81/91.10 | 64.01 |
| AMSA | 0.786 | 84.26/53.27 | 38.89/90.56 | 61.14 |
| SIGNINT | 0.772 | 84.26/54.90 | 39.74/90.81 | 62.56 |
| MS | 0.784 | 84.26/55.56 | 40.09/90.91 | 63.04 |
| PSA | 0.776 | 84.26/53.57 | 39.22/90.66 | 61.84 |
The parameter comparison sheet that the method for table 1 present invention and existing algorithm obtain
The method of the present invention can be built in defibrillator, is analyzed the state of patient's electrocardiosignal.At cardiopulmonary
In resuscitation process, real-time calculating phase space scale parameter, evaluate carry out this moment defibrillation can successful probability,
There is provided the need of the guiding opinion of defibrillation at once to first-aid personnel, to reach optimal defibrillation effect.
A kind of defibrillator, as shown in Figure 4, including ecg signal acquiring module, is used for gathering patient's electrocardiogram (ECG) data；
Electrocardiosignal time delay module, for choosing the described electrocardiogram (ECG) data of 0.1s～10s and carrying out described electrocardiogram (ECG) data
Time delay；Electrocardiogram (ECG) data processing module, for carrying out two dimension Scatter plot, institute to the electrocardiogram (ECG) data after described time delay
Stating the electrocardiogram (ECG) data chosen is abscissa, and the signal after time delay is that ordinate draws two dimension scatter diagram, obtains scatterplot
Scatterplot data are divided by the peak width Width of data distribution and standard B of evaluation scatterplot data distributing homogeneity
Standard B of the peak width Width of cloth and evaluation scatterplot data distributing homogeneity carries out mathematical modeling, calculates
Phase space yardstick PSS；Output module, exports prompting for the value according to described phase space yardstick PSS and builds
View, described ecg signal acquiring module, electrocardiosignal time delay module, electrocardiogram (ECG) data processing module and output module
It is sequentially connected with.
Ecg signal acquiring module gathers ecg signal data, is obtained the electrocardiosignal of patient by defibrillation electrode,
And pre-processed by bandpass filter, bandpass filter frequency range is 2Hz～48Hz.
Electrocardiosignal time delay module carries out time delay for electrocardiogram (ECG) data ecg signal acquiring module collected, tool
Body process is: select the electrocardiogram (ECG) data image of 0.1s～10s to be analyzed, by choose with rectangular window before defibrillation
After signal carries out time delay τ, and draw as ordinate of orthogonal axes using original signal as transverse axis coordinate, the signal after time delay
Two dimension scatter diagram, is mapped to one-dimensional electrocardiogram (ECG) data on two dimensional surface, wherein τ=3ms.
The concrete processing procedure of ECG's data compression module: the two-dimentional scatter diagram of the electrocardiogram (ECG) data after time delay is entered
Row is analyzed, and calculates each scatterplot distance to straight line x=y, finds distance d, makes the distance sample point less than d
Account for the 95% of all data points, and with 1.5d as boundary, distance value is more than getting rid of a little of 1.5d, away from
Distance values is a little exceptional data point more than 1.5d's.Calculate the distance maximum in straight line x=y two side data
And it is added the peak width Width, Width=max obtaining the distribution of scatterplot dataup+maxdown, wherein, Width
Represent the peak width of scatterplot data distribution, maxupFor top scatterplot away from straight line x=y apart from farthest numerical value,
maxdownFor bottom scatterplot away from straight line x=y apart from farthest numerical value.Line of demarcation is done for standard, meter with Width/2
The data point sum N that point counting boundary line is upper and lower, the difference counted up and down using line of demarcation is as evaluating the distribution of scatterplot data
Standard B:B=of uniformity | Nup-Ndown|, wherein NupRepresent the data point sum on top, line of demarcation, Ndown
Represent the data point sum of bottom, line of demarcation.The comprehensive peak width Width analyzing the distribution of scatterplot data and number
According to the degree B founding mathematical models that is evenly distributed, calculating is for predicting the phase space yardstick PSS of defibrillation usefulness:
PSS=K*Width Y*B, wherein, K is scatterplot width weight coefficient, and Y is the weight coefficient of uniformity coefficient.
When sample rate is fixed as 300Hz, K value 10, Y changes adjustment, when taking 0.5 according to analyzing data length
When second data is analyzed, Y value 0.0004.Obtain through substantial amounts of experiment: K value is fixed as 10, B
Value is fixed as 0.0004, and sample rate is not fixed, and the result calculated is not had too much influence, it may be assumed that PSS=10*
Width–0.0004*B。
Output module, the value of the phase space yardstick PSS obtained according to ECG's data compression resume module judges defeated
Go out prompting, when phase space yardstick PSS is more than or equal to 0.45, it was predicted that the successful probability of defibrillation is very big,
Output module output prompting suggestion defibrillation, when phase space yardstick PSS is less than 0.45, it was predicted that defibrillation failure
Likelihood ratio bigger, it is not recommended that defibrillation, output module output prompting continue pressing.
Finally illustrating, above example is only in order to illustrate technical scheme and unrestricted, although ginseng
According to preferred embodiment, the present invention is described in detail, it will be understood by those within the art that, permissible
Technical scheme is modified or equivalent, without deviating from technical solution of the present invention objective and
Scope, it all should be contained in the middle of scope of the presently claimed invention.
Claims (4)
1. a defibrillator, it is characterised in that: include ecg signal acquiring module, be used for gathering patient's electrocardiogram (ECG) data；
Electrocardiosignal time delay module, for choosing the electrocardiogram (ECG) data of 0.1s～10s and to the heart choosing 0.1s～10s
Electricity data carry out time delay；Electrocardiogram (ECG) data processing module, for carrying out two dimension scatterplot to the electrocardiogram (ECG) data after time delay
Analyze, described in the electrocardiogram (ECG) data of 0.1s～10s chosen be abscissa, the electrocardiogram (ECG) data after time delay is sat for vertical
Mark and draw system two dimension scatter diagram, calculate each scatterplot distance d to straight line x=y, find distance d, make apart from little
Sample point in d accounts for the 95% of all data points, and with 1.5d as boundary, gets rid of distance value more than 1.5d
Exceptional data point, calculate the distance maximum in straight line x=y two side data and addition obtain scatterplot data and divides
The peak width Width:Width=max of clothup+maxdown, wherein, Width is the district of scatterplot data distribution
Field width degree, maxupFor top scatterplot away from straight line x=y apart from farthest numerical value, maxdownFor bottom scatterplot away from directly
Line x=y is apart from farthest numerical value；Do line of demarcation with Width/2 for standard, calculate the data that line of demarcation is upper and lower
Point sum N, the difference counted up and down using line of demarcation is as standard B:B=evaluating scatterplot data distributing homogeneity
|Nup-Ndown|, wherein, NupRepresent the data point sum on top, line of demarcation, NdownRepresent the number of bottom, line of demarcation
Strong point sum, the peak width Width that scatterplot data are distributed and the mark of evaluation scatterplot data distributing homogeneity
Quasi-B carries out mathematical modeling, calculates phase space yardstick PSS；Output module, for according to described phase place
Space scale PSS value output prompting suggestion, described ecg signal acquiring module, electrocardiosignal time delay module,
Electrocardiogram (ECG) data processing module and output module are sequentially connected with.
2. defibrillator as claimed in claim 1, it is characterised in that: described electrocardiogram (ECG) data processing module calculates phase place
The formula of space scale PSS: PSS=K*Width-Y*B, wherein, K is scatterplot width weight coefficient, Y
For the weight coefficient of uniformity coefficient, Width is the peak width of scatterplot data distribution, and B is for evaluating scatterplot data
The standard of distributing homogeneity.
3. defibrillator as claimed in claim 1, it is characterised in that: described electrocardiogram (ECG) data processing module calculates phase place
The formula of space scale PSS: PSS=10*Width-0.0004*B, wherein, Width is scatterplot data
The peak width of distribution, B is the standard evaluating scatterplot data distributing homogeneity.
4. defibrillator as claimed in claim 1, it is characterised in that: when the value of described phase space yardstick PSS is big
When equal to 0.45, described output module output prompting suggestion defibrillation, described phase space yardstick PSS value is little
In 0.45 time, the output suggestion of described output module continues pressing.
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| CN112315485B (en) * | 2019-07-18 | 2023-06-23 | 查宇亮 | Quality capability quantitative evaluation method based on asymmetric cardiac cycle change |
| CN111803054B (en) * | 2020-06-12 | 2023-04-07 | 中国人民解放军陆军军医大学 | Method and instrument for evaluating ventricular fibrillation signal quality and defibrillation success rate in real time |
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| CN101461709A (en) * | 2009-01-12 | 2009-06-24 | 复旦大学 | Shockable rhythm recognition algorithm based on slope absolute value distribution dispersion |
| CN103007431A (en) * | 2012-12-31 | 2013-04-03 | 深圳邦健生物医疗设备股份有限公司 | Device and method for shockable signal detection |
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| DE10163348A1 (en) * | 2001-12-21 | 2003-07-10 | Hans D Esperer | Method and device for the automated detection and differentiation of cardiac arrhythmias |
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| US5645070A (en) * | 1995-09-25 | 1997-07-08 | Ventritex, Inc. | Method and apparatus for determining the origins of cardiac arrhythmias morphology dynamics |
| CN101461709A (en) * | 2009-01-12 | 2009-06-24 | 复旦大学 | Shockable rhythm recognition algorithm based on slope absolute value distribution dispersion |
| CN103007431A (en) * | 2012-12-31 | 2013-04-03 | 深圳邦健生物医疗设备股份有限公司 | Device and method for shockable signal detection |
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