CN104225359A - Jiangtangjia tablet and preparation method thereof - Google Patents
Jiangtangjia tablet and preparation method thereof Download PDFInfo
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- CN104225359A CN104225359A CN201410402614.2A CN201410402614A CN104225359A CN 104225359 A CN104225359 A CN 104225359A CN 201410402614 A CN201410402614 A CN 201410402614A CN 104225359 A CN104225359 A CN 104225359A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 238000001035 drying Methods 0.000 claims abstract description 15
- 210000000582 semen Anatomy 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 9
- 239000008280 blood Substances 0.000 claims description 29
- 210000004369 blood Anatomy 0.000 claims description 29
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 28
- 239000006071 cream Substances 0.000 claims description 21
- 239000000843 powder Substances 0.000 claims description 21
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 14
- 239000001569 carbon dioxide Substances 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 14
- 239000009636 Huang Qi Substances 0.000 claims description 9
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 8
- 229930091371 Fructose Natural products 0.000 claims description 8
- 239000005715 Fructose Substances 0.000 claims description 8
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 8
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 8
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 8
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 8
- 238000004132 cross linking Methods 0.000 claims description 8
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 8
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 8
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 8
- 229960003943 hypromellose Drugs 0.000 claims description 8
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 8
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 8
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 8
- 239000008517 radix Trichosanthis Substances 0.000 claims description 8
- 239000000741 silica gel Substances 0.000 claims description 8
- 229910002027 silica gel Inorganic materials 0.000 claims description 8
- 229910052708 sodium Inorganic materials 0.000 claims description 8
- 239000011734 sodium Substances 0.000 claims description 8
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 8
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 8
- 206010013786 Dry skin Diseases 0.000 claims description 7
- 229920002472 Starch Polymers 0.000 claims description 7
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims description 7
- 239000000284 extract Substances 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 7
- 239000008187 granular material Substances 0.000 claims description 7
- 238000000227 grinding Methods 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 239000008107 starch Substances 0.000 claims description 7
- 235000019698 starch Nutrition 0.000 claims description 7
- 238000000194 supercritical-fluid extraction Methods 0.000 claims description 7
- 238000005550 wet granulation Methods 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 5
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 7
- 241000045403 Astragalus propinquus Species 0.000 abstract description 3
- 235000006533 astragalus Nutrition 0.000 abstract description 3
- 241000405414 Rehmannia Species 0.000 abstract 1
- 238000003815 supercritical carbon dioxide extraction Methods 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 230000010354 integration Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 1
- 244000077995 Coix lacryma jobi Species 0.000 description 1
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241000013557 Plantaginaceae Species 0.000 description 1
- 241001038563 Pseudostellaria Species 0.000 description 1
- 240000006023 Trichosanthes kirilowii Species 0.000 description 1
- 235000009818 Trichosanthes kirilowii Nutrition 0.000 description 1
- 241000975594 Trichosanthes rosthornii Species 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000004345 fruit ripening Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Jiangtangjia tablet and a preparation method thereof. The Jiangtangjia tablet disclosed by the invention is characterized by being prepared from the following components: 428.4g of astragalus membranaceus, 300g of semen coicis, 428.4g of rehmannia, 428.4g of radix pseudostellariae, and 428.4g of radices trichosanthis. The preparation method comprises the following steps of: extracting by using a supercritical carbon dioxide extraction method, drying under reduced pressure, crushing into nano dry paste by using a high-energy nano impact mill, and adding functional auxiliaries, thus obtaining the Jiangtangjia tablet. The Jiangtangjia tablet provided by the invention has the advantages that the disintegration time is obviously shortened; the curative effect is obviously prior to that of the commercial Jiangtangjia tablet; and active effects are obtained.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of blood sugar lowering first sheet and preparation method thereof.
Background technology
Blood sugar lowering first sheet is used for type 2 diabetes mellitus.Existing blood sugar lowering first sheet is due to prescription and technological reason, and curative effect is not satisfactory, and preparation adopts traditional handicraft preparation, there is the deficiencies such as prolonged disintegration, curative effect are low.
Summary of the invention
The present invention, for overcoming above-mentioned deficiency, provides blood sugar lowering first sheet that a kind of disintegration rate is fast, curative effect is high and preparation method thereof.
Invention embodiment is as follows:
Get Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, employing carbon dioxide supercritical extraction method is extracted, extracting pressure 20 ~ 40Mpa, extraction temperature 20 ~ 40 DEG C, separator pressure 10 ~ 20Mpa, separator temperature 40 ~ 60 DEG C, disengaging time 2 ~ 4 hours, carbon dioxide flow 20 ~ 40L per hour, obtains extracting solution; Get extracting solution 60 DEG C ~ 80 DEG C drying under reduced pressure, get dry extract; Get dry cream and add fructose 80 ~ 120g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 35 ~ 45g, crospolyvinylpyrrolidone 35 ~ 45g, cross-linking sodium carboxymethyl cellulose 35 ~ 45g, hypromellose 25 ~ 35g, micropowder silica gel 15 ~ 25g, mix homogeneously, with 50 ~ 70% ethanol wet granulations, 60 DEG C ~ 80 DEG C dryings, additional carboxymethyl starch sodium 7 ~ 9g, granulate, be pressed into 3000, obtained blood sugar lowering first sheet.
The raw material standards that above-mentioned embodiment is mentioned is as follows:
The Radix Astragali: China's coastal port one ministerial standard.This product is leguminous plant Radix Astagali Astragalus membranaceus(Fisch.) Bge.var.mongholicus(Bge.) Hsiao or Radix Astragali Astragalus membranaceus(Fisch.) Bge, dry root.Spring, autumn two, Lee excavated, and removing fibrous root and root head, dry.
Semen Coicis: China's coastal port one ministerial standard.This product is grass Semen Coicis Coix lacryma-jobi L.var.ma-yuen(ROman.) dry mature kernal of Stapf.Tap plant during fruit maturation in autumn, dry, lay fruit, then dry, except decapsidate, yellowish-brown seed coat and impurity, collect kernel.
Radix Rehmanniae: China's coastal port one ministerial standard.This product is the fresh or dried root of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch..Autumn excavates, except removing LU, fibrous root and silt, and using fresh herb; Or Radix Rehmanniae is slowly cured to about most probably dry.The former practises title " Radix Rehmanniae ", and the latter practises title " Radix Rehmanniae ".
Radix Pseudostellariae: China's coastal port one ministerial standard.This product is pinkwort Radix Ginseng Pseudostellaria beterphylla(Miq) Pax ex Pax et Hoffm.Dried root.Summer excavates when stem and leaf major part is withered, cleans, removing fibrous root, puts after slightly scalding in boiling water and dries or directly dry.
Radix Trichosanthis: China's coastal port one ministerial standard.This product is the dry root of cucurbitaceous plant Fructus Trichosanthis Trichosanthes kirilowii Maxim. or trichosanthes rosthornii Harms Trichosanthes rosthornii Harms.Autumn, season in winter two excavate, and clean, removing crust, and cutting or vertical profile become lobe, dry.
Fructose: Chinese Pharmacopoeia version two ministerial standard in 2010.
Microcrystalline Cellulose: Chinese Pharmacopoeia version two ministerial standard in 2010.
Crospolyvinylpyrrolidone: Chinese Pharmacopoeia version two ministerial standard in 2010.
Cross-linking sodium carboxymethyl cellulose: Chinese Pharmacopoeia version two ministerial standard in 2010.
Hypromellose: Chinese Pharmacopoeia version two ministerial standard in 2010.
Micropowder silica gel: Chinese Pharmacopoeia version two ministerial standard in 2010.
Carboxymethylstach sodium: Chinese Pharmacopoeia version two ministerial standard in 2010.
Raw material used by above blood sugar lowering first sheet all can be bought from pharmaceuticals and obtain, and all can be used to implement the present invention program as long as meet national standard.
In foregoing invention scheme, term used is pharmacy proprietary term, as " decompression " etc. all defers to Chinese Pharmacopoeia regulation and pharmaceutical practice of being correlated with.
Unit g in the present invention also can be other weight portion, does not affect the enforcement of the present invention program.
Equipment Market described in the present invention program all has sale, is not limited to typical production producer, as long as technical specification can reach requirement, all can be used to realize the present invention.
Four detailed description of the invention
Specific embodiments of the invention 1
Get Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, employing carbon dioxide supercritical extraction method is extracted, extracting pressure 20Mpa, extraction temperature 20 DEG C, separator pressure 10Mpa, separator temperature 40 DEG C, disengaging time 2 hours, carbon dioxide flow 20L per hour, obtains extracting solution; Get extracting solution 60 DEG C of drying under reduced pressure, get dry extract; Get dry cream and add fructose 80g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 35g, crospolyvinylpyrrolidone 35g, cross-linking sodium carboxymethyl cellulose 35g, hypromellose 25g, micropowder silica gel 15g, mix homogeneously, with 50% ethanol wet granulation, 60 DEG C of dryings, additional carboxymethyl starch sodium 7g, granulate, be pressed into 3000, obtained blood sugar lowering first sheet.
Specific embodiments of the invention 2
Get Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, employing carbon dioxide supercritical extraction method is extracted, extracting pressure 40Mpa, extraction temperature 40 DEG C, separator pressure 20Mpa, separator temperature 60 DEG C, disengaging time 4 hours, carbon dioxide flow 40L per hour, obtains extracting solution; Get extracting solution 80 DEG C of drying under reduced pressure, get dry extract; Get dry cream and add fructose 120g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 45g, crospolyvinylpyrrolidone 45g, cross-linking sodium carboxymethyl cellulose 45g, hypromellose 35g, micropowder silica gel 25g, mix homogeneously, with 70% ethanol wet granulation, 80 DEG C of dryings, additional carboxymethyl starch sodium 9g, granulate, be pressed into 3000, obtained blood sugar lowering first sheet.
Specific embodiments of the invention 3
Get Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, employing carbon dioxide supercritical extraction method is extracted, extracting pressure 30Mpa, extraction temperature 30 DEG C, separator pressure 15Mpa, separator temperature 50 DEG C, disengaging time 3 hours, carbon dioxide flow 30L per hour, obtains extracting solution; Get extracting solution 70 DEG C of drying under reduced pressure, get dry extract; Get dry cream and add fructose 100g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 40g, crospolyvinylpyrrolidone 40g, cross-linking sodium carboxymethyl cellulose 40g, hypromellose 30g, micropowder silica gel 20g, mix homogeneously, with 60% ethanol wet granulation, 70 DEG C of dryings, additional carboxymethyl starch sodium 8g, granulate, be pressed into 3000, obtained blood sugar lowering first sheet.
Above embodiment illustrates, adopts the extreme condition of embodiment of the present invention and optimal conditions all can make blood sugar lowering first sheet.Actual effect of the present invention is investigated below with the blood sugar lowering first sheet that embodiment 3 is obtained:
(1) embodiment 3 blood sugar lowering first sheet and commercially available blood sugar lowering first sheet contrast disintegration
1 disintegration time mensuration method
Measure by Chinese Pharmacopoeia version annex Ⅻ A in 2010.
Contrast 2 disintegrations
Table 1 embodiment 3 blood sugar lowering first sheet and commercially available blood sugar lowering first sheet contrast table disintegration
The above results shows, blood sugar lowering first sheet prepared by the present invention has the remarkable advantages such as disintegration rate is fast, bioavailability is high relative to commercially available blood sugar lowering first sheet.
(2) embodiment 3 blood sugar lowering first sheet and commercially available blood sugar lowering first sheet treat type 2 diabetes mellitus clinical observation on the therapeutic effect
1 case scenario
Statistics outpatient service and inpatient, observe type 2 diabetes mellitus case 110 example, 55 years old mean age altogether.Patient is divided into two groups, test group takes embodiment 3 blood sugar lowering first sheet, and matched group takes commercially available blood sugar lowering first sheet.
2 efficacy assessment standards
According to new Chinese medicine treatment diabetes guideline of clinical investigations tcm syndrome curative effect determinate standard:
Clinical recovery: tcm clinical practice symptom, sign disappear or substantially disappear, syndrome integral reduces >=90%.
Effective: tcm clinical practice symptom, sign are obviously improved, syndrome integral reduces >=70%.
Effective: tcm clinical practice symptom, sign all take a favorable turn, syndrome integral reduces >=30%.
Invalid: tcm clinical practice symptom, sign are all not improved or increase the weight of, syndrome integral reduces < 30%.
Computing formula: [before (before treatment the rear integration of integration-treatment) ÷ treatment integration] × 100%.
3 clinical observation result
Table 2 embodiment 3 blood sugar lowering first sheet and commercially available blood sugar lowering first sheet clinical efficacy contrast table
Above-mentioned clinical observation on the therapeutic effect result shows, blood sugar lowering first sheet prepared by the present invention is when treating type 2 diabetes mellitus, evident in efficacy higher than commercially available blood sugar lowering first sheet, p < 0.05.
Claims (3)
1. treat a Chinese medicine for type 2 diabetes mellitus, it is characterized in that getting Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, adopt carbon dioxide supercritical extraction method to extract, extracting pressure 20 ~ 40Mpa, extraction temperature 20 ~ 40 DEG C, separator pressure 10 ~ 20Mpa, separator temperature 40 ~ 60 DEG C, disengaging time 2 ~ 4 hours, carbon dioxide flow 20 ~ 40L per hour, obtains extracting solution; Get extracting solution 60 DEG C ~ 80 DEG C drying under reduced pressure, get dry extract; Get dry cream and add fructose 80 ~ 120g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 35 ~ 45g, crospolyvinylpyrrolidone 35 ~ 45g, cross-linking sodium carboxymethyl cellulose 35 ~ 45g, hypromellose 25 ~ 35g, micropowder silica gel 15 ~ 25g, mix homogeneously, with 50 ~ 70% ethanol wet granulations, 60 DEG C ~ 80 DEG C dryings, additional carboxymethyl starch sodium 7 ~ 9g, granulate, obtained blood sugar lowering first sheet.
2. the preparation method of Chinese medicine according to claim 1, is characterized in that getting Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, adopt carbon dioxide supercritical extraction method to extract, extracting pressure 20 ~ 40Mpa, extraction temperature 20 ~ 40 DEG C, separator pressure 10 ~ 20Mpa, separator temperature 40 ~ 60 DEG C, disengaging time 2 ~ 4 hours, carbon dioxide flow 20 ~ 40L per hour, obtains extracting solution; Get extracting solution 60 DEG C ~ 80 DEG C drying under reduced pressure, get dry extract; Get dry cream and add fructose 80 ~ 120g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 35 ~ 45g, crospolyvinylpyrrolidone 35 ~ 45g, cross-linking sodium carboxymethyl cellulose 35 ~ 45g, hypromellose 25 ~ 35g, micropowder silica gel 15 ~ 25g, mix homogeneously, with 50 ~ 70% ethanol wet granulations, 60 DEG C ~ 80 DEG C dryings, additional carboxymethyl starch sodium 7 ~ 9g, granulate, obtained blood sugar lowering first sheet.
3. the preparation method of Chinese medicine according to claim 1, gets Radix Astragali 428.4g, Semen Coicis 300g, Radix Rehmanniae 428.4g, Radix Pseudostellariae 428.4g, Radix Trichosanthis 428.4g, be ground into 60 order coarse powder, adopt carbon dioxide supercritical extraction method to extract, extracting pressure 30Mpa, extraction temperature 30 DEG C, separator pressure 15Mpa, separator temperature 50 DEG C, disengaging time 3 hours, carbon dioxide flow 30L per hour, obtains extracting solution; Get extracting solution 70 DEG C of drying under reduced pressure, get dry extract; Get dry cream and add fructose 100g, adopt the impact grinding of high energy nanometer to be ground into the mixing dried cream powder of particle diameter 200 ~ 300nm; Get mixing dried cream powder, microcrystalline Cellulose 40g, crospolyvinylpyrrolidone 40g, cross-linking sodium carboxymethyl cellulose 40g, hypromellose 30g, micropowder silica gel 20g, mix homogeneously, with 60% ethanol wet granulation, 70 DEG C of dryings, additional carboxymethyl starch sodium 8g, granulate, be pressed into 3000, obtained blood sugar lowering first sheet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410402614.2A CN104225359A (en) | 2014-08-16 | 2014-08-16 | Jiangtangjia tablet and preparation method thereof |
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| CN201410402614.2A CN104225359A (en) | 2014-08-16 | 2014-08-16 | Jiangtangjia tablet and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029092A (en) * | 2017-04-13 | 2017-08-11 | 杨万政 | A kind of mare's milk sugar-reduction traditional Chinese medicine composition and its preparation method and application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600234A (en) * | 2012-04-13 | 2012-07-25 | 孙长海 | Swertia mileensis dispersible tablet and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102600234A (en) * | 2012-04-13 | 2012-07-25 | 孙长海 | Swertia mileensis dispersible tablet and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 李桂荣等: "渴乐宁胶囊中黄芪甲苷的含量测定", 《中国药业》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029092A (en) * | 2017-04-13 | 2017-08-11 | 杨万政 | A kind of mare's milk sugar-reduction traditional Chinese medicine composition and its preparation method and application |
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Application publication date: 20141224 |