CN104225111A - Traditional Chinese medicine composition for chronic pancreatitis treatment and preparation method application thereof - Google Patents

Traditional Chinese medicine composition for chronic pancreatitis treatment and preparation method application thereof Download PDF

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CN104225111A
CN104225111A CN 201410564326 CN201410564326A CN104225111A CN 104225111 A CN104225111 A CN 104225111A CN 201410564326 CN201410564326 CN 201410564326 CN 201410564326 A CN201410564326 A CN 201410564326A CN 104225111 A CN104225111 A CN 104225111A
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chronic pancreatitis
treatment
chinese medicine
medicine composition
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CN 201410564326
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杨文君
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杨文君
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Abstract

The invention provides a traditional Chinese medicine composition for chronic pancreatitis treatment and is prepared by utilizing the raw materials, by weight, comprising 13 parts of didymocarpus yunnanensis, 14 parts of diploclisia glaucescens, 10 parts of dodartia orientalis, 12 parts of elatostema obtusum, 16 parts of epilobium parviflorum, 12 parts of rhizome of Asian baneberry, 14 parts of brachystemma calycinum, 16 parts of acorus gramineus, 12 parts of gluey bark litse, 15 parts of cyathula prostrata, 12 parts of lysimachia capillipes hemsl, 14 parts of ixeris japonica, 8 parts of berchemia yunnanensis franch, 16 parts of calogyne pilosa, 13 parts of mesona blumes, 12 parts of zygophyllum fabago, 10 parts of cavalerie mosla herb, 12 parts of caibiodendron yunnanensel and 14 parts of passion flower. The traditional Chinese medicine composition for chronic pancreatitis treatment can be used for treating chronic pancreatitis.

Description

-种治疗慢性膜腺炎的中药组合物及制备方法和应用 - Chinese herb composition and preparation method and application in the treatment of chronic pancreatitis

技术领域 FIELD

[0001] 本发明涉及中药技术领域,具体涉及一种治疗慢性膜腺炎的中药组合物及制备方法和应用。 [0001] Technical Field The present invention relates to medicine, particularly relates to compositions and preparation method and application of traditional Chinese medicine of treating chronic pancreatitis.

背景技术 Background technique

[0002] 慢性膜腺炎是由于胆道疾病或酒精中毒等因素导致的膜腺实质进行性损害和纤维化,常伴巧化、假性囊肿及膜岛细胞减少或萎缩。 [0002] Chronic pancreatitis is a gland in real terms due to the film such as alcoholism or biliary tract disease factors leading to progressive damage and fibrosis, often accompanied by clever, and reduce or shrink film pseudocyst and islet cells. 主要表现为腹痛、消瘦、营养不良、腹泻或脂肪痴,后期可出现腹部包块、黄痘和糖尿病等。 Mainly as abdominal pain, weight loss, malnutrition, diarrhea or fat crazy, post-abdominal mass may appear yellow pox and diabetes. 目前缺少有效的治疗药物。 The current lack of effective treatments.

发明内容 SUMMARY

[000引发明目的;为了解决上述问题,本发明的目的在于提供一种治疗慢性膜腺炎的中药组合物及制备方法和应用。 [000 initiator eyesight; To solve the above problems, an object of the present invention to provide compositions and traditional Chinese medicine preparation method and application in the treatment of chronic pancreatitis.

[0004] 技术方案;本发明的目的是通过如下的方案实现的: [0004] Technical Solution; object of the present invention are achieved by the following scheme:

[0005] -种治疗慢性膜腺炎的中药组合物,它由如下重量份数的原料制备得到;云南长菊宦苔13g、苍白称钩风14g、野胡麻lOg、纯叶楼梯草12g、小花柳叶菜16g、绿豆升麻12g、 短瓣花14g、随手香16g、渥稿树12g、蛇见怕15g、排草香12g、剪刀股14g、鸭公青8g、离根香16g、凉粉草13g、骆驼蹄瓣12g、星色草lOg、金叶子12g、转也莲14g。 [0005] - chronic pancreatitis therapeutic medicine composition was prepared from the following ingredients by weight; 13g Yunnan long daisy Huan moss, said hook pale wind 14g, wild flax lOg, pure Elatostema leaf 12g, a small venereal leafy vegetables 16g, green beans Cimicifuga 12g, short flower petals 14g, readily incense 16g, Ottawa art tree 12g, a snake or fear 15g, ranked grassy 12g, scissors stocks 14g, male duck green 8g, from incense sticks 16g, 13g grass jelly , camel hoof valve 12g, satellite color grass lOg, gold leaf 12g, lotus also turn 14g.

[0006] 所述治疗慢性膜腺炎的中药组合物在制备治疗慢性膜腺炎的药物中的应用。 [0006] The medicament for treatment of chronic pancreatitis Chinese medicine composition in preparing the treatment of chronic pancreatitis in.

[0007] 本发明中云南长菊宦苔为苦宦苔科长菊宦苔属下的一个种。 [0007] The present invention Yunnan chrysanthemum long as one kind of bitter Huan Huan moss moss moss under the chief official chrysanthemum. 拉下名为Didymoca巧US yunnanensis (Rranch. )WW Smith,产云南,四川西南部,印度东北部。 Pull down the name Didymoca Qiao US yunnanensis (Rranch.) WW Smith, Industry of Yunnan, Sichuan, southwest, northeast India. 全草: 宣肺止咳,散癒消肿,止血止痛,促进伤口愈合。 The whole plant: Xuanfei cough, the more scattered swelling, bleeding and pain, promote wound healing. 用于咳嗽,支气管炎,劳伤腰痛,癒血肿痛, 外治刀枪伤,跌打损伤,骨折。 For cough, bronchitis, injured workers back pain, swelling and pain more blood, outside the rule swords and guns injury, bruises, fractures. 本发明W全草入药。 W whole plant medicine of the present invention.

[0008] 苍白称钩风是防已科植物苍白砰钩风的藤茎,拉下名为Diploclisia glaucescens(Bl. )Diels,产华南,云南,福建,江西。 [0008] pale said hook is anti-wind plants have pale cane bang hook wind down the name Diploclisia glaucescens (Bl.) Diels, production in South China, Yunnan, Fujian, Jiangxi. 茎藤,叶;清热解毒,巧风除湿。 Vine stems and leaves; detoxification, clever wind and dampness. 用于风湿骨痛,小便淋痛,尿路感染,胆囊炎,咽喉痛,痴疾,毒蛇咬伤。 For rheumatic pain, painful urination, urinary tract infections, cholecystitis, sore throat, crazy disease, snake bites.

[0009] 野胡麻为玄参科野胡麻属多年生直立草本,高15-50厘米,无毛或幼嫩时疏被柔毛。 [0009] Scrophulariaceae wild wild flax flax erect perennial herb, 15-50 cm high, sparsely pubescent young or hairless. 拉下名为Dodartia orientalis L,产内蒙古,宁夏,甘肃,新疆,四川,蒙古,苏联,伊朗。 Pull down the name Dodartia orientalis L, produced in Inner Mongolia, Ningxia, Gansu, Xinjiang, Sichuan, Mongolia, the Soviet Union, Iran. 清热解毒,散风止痒。 Detoxify, scattered wind itching. 用于老年慢性气管炎,咳嗽姨喘,小儿肺炎,扁桃体炎,淋己结炎, 乳蛾,乳痛,结膜炎,目赤,尿道感染,小便淋痛,肾虚。 For elderly patients with chronic bronchitis, cough aunt asthma, infantile pneumonia, tonsillitis, inflammation of lymph nodes hexyl, milk moth, breast pain, conjunctivitis, eyes, urinary tract infections, urination pain, kidney. 外用于湿疹,専麻疹,皮肤瘦痒,神经衰弱。 Outside for eczema, hives, Graduate, thin skin itch, neurasthenia. 本发明W全草入药。 W whole plant medicine of the present invention.

[0010] 纯叶楼梯草为専麻科楼梯草属的植物。 [0010] Pure grass leaves stairs Graduate Division Elatostema hemp plant. 拉了名为Elatostema obtusum Wedd.,产陕西,甘肃,湖北,四川,云南,西藏。 Pull called Elatostema obtusum Wedd., Production Shaanxi, Gansu, Hubei, Sichuan, Yunnan and Tibet. 全草:清热解毒,巧癒止痛。 The whole plant: detoxification, the more clever pain. 本发明W全草入药。 W whole plant medicine of the present invention.

[0011] 小花柳叶菜为柳叶菜科柳叶菜属多年生草本植物,拉下名为邱ilobium parviflorumSc虹eb.,产东北,华中,陕西,甘肃,新疆。 [0011] Epilobium parviflorum is Onagraceae Epilobium perennial herb, named Qiu ilobium parviflorumSc down rainbow eb., Producing northeast, central China, Shaanxi, Gansu, Xinjiang. 全草:清热解毒,疏风镇咳。 The whole plant: detoxification, Shufeng cough. 根;用于劳伤腰痛。 Root; for injured workers back pain. 全草:用于泄泻,疗疮,咳嗽。 The whole plant: For diarrhea, sore, cough. 本发明W全草入药。 W whole plant medicine of the present invention.

[0012] 绿豆升麻为毛畏科类叶升麻属植物类叶升麻Actaea asiatica Hara, W根状茎及全草入药。 [0012] mung bean plant Cimicifuga Cimicifuga racemosa Actaea asiatica Hara fear for the hair department Cimicifuga racemosa, W rhizomes and whole plant medicine. 秋季采集,分别晒干。 Fall collection, dried, respectively. 清肺止咳,清热解毒。 Qingfeizhike, detoxification. 用于感冒头痛,百日咳。 For colds, headache, whooping cough. 外用治犬咬伤。 Topical treatment of dog bites. 本发明W全草入药。 W whole plant medicine of the present invention.

[0013] 短瓣花为石竹科短瓣花属植物短瓣花化achystemma calycinum D. Don, W带根全草入药。 [0013] short-petal flower petal flower Caryophyllaceae short genus of flower petals short achystemma calycinum D. Don, W whole plant with roots used as medicine. 全年可采,洗净,鲜用或晒干。 Annual recoverable, washed, fresh or dried. 清热解毒,舒筋活络。 Detoxification, getting a vivid. 根;用于白喉,风湿瘍痛,跌打损伤,月经不调,病后虚弱。 Root; for diphtheria, rheumatic pain Ulcers, bruises, irregular menstruation, weakness after disease. 茎、叶:外用治手足痊李,骨折。 Stems, leaves: Topical treatment of hand, foot and recover from illness Lee, fracture.

[0014] 随手香为天南星科营蒲属植物随手香Acorus gramineus Soland. var.pusillus 化suaveolens CY化eng, mss.,W全草入药。 [0014] readily camp Po Hong Araceae species readily Hong Acorus gramineus Soland. Var.pusillus of suaveolens CY of eng, mss., W whole plant medicine. 四季可采,晒干。 Four Seasons recoverable, and dried. 行气止痛,巧风逐寒,解毒利水,豁姨开菌。 Gas pain, clever by cold wind, detoxification benefits of water, excluded aunt opened bacteria. 用于姨迷也菌,神志昏迷,牙关紧闭,胸闷腹痛,湿浊中阻,风湿关节痛,疵痛,水肿;外用治无名肿毒。 Aunt also fans for bacteria, delirium, trismus, chest pain, dampness in the resistance, rheumatoid arthritis, defect pain, edema; topical treatment of swelling of unknown origin.

[0015] 渥稿树为棒科木姜子属植物渥稿树Litsea glutinosa(Lour. )CB Rob.,W根、 皮、叶入药,清湿热,消肿毒,止血,止痛。 [0015] Ottawa art tree branch to stick Litsea plant Ottawa art tree Litsea glutinosa (Lour.) CB Rob., W roots, bark, leaves used as medicine, clearing heat, swelling drugs, bleeding, pain. 根;内服治腹泻,跌打损伤,腮腺炎,糖尿病。 Root; Oral treatment of diarrhea, bruises, mumps, diabetes. 皮、 叶;外用治腮腺炎,疮巧痛肿,乳腺炎初起,跌打损伤,外伤出血。 Leather, leaf; topical treatment of mumps, sore clever pain and swelling, mastitis early, bruises, trauma bleeding. 本发明W根入药 W root medicine of the present invention

[0016] 蛇见怕为觅科杯觅属植物杯觅切athula prostrata(L. )Blume, W根或全草入药。 [0016] snake or fear athula prostrata (L.) Blume, W root or whole plant medicine is to find families cup cup seek to find plants cut. 四季可采,鲜用或晒干。 Four Seasons recoverable, fresh or dried. ;根:清热解毒。 ; Root: detoxification. 用于细菌性痴疾。 Crazy for bacterial disease. 全草:消积除姨,消肿止痛。 The whole plant: consumer product except aunt, swelling and pain. 用于小儿衙积,肝脾肿大,肺结核,蛇咬伤,跌打损伤,疮瘍肿毒。 For children Ya plot, hepatosplenomegaly, tuberculosis, snake bites, bruises, sore swollen poison. 本发明W全草入药。 W whole plant medicine of the present invention.

[0017] 排草香为报春花科排草属植物细梗排草Lysimachia capillipes Hemsl.的全草。 [0017] Primulaceae row to row grassy plants of the genus gracilipes Lysimachia Lysimachia capillipes Hemsl. The whole plant. 夏秋采集,阴干。 Summer and fall collection, dried. 巧风,止咳,调经。 Qiao wind, cough, menstruation. 用于感冒咳嗽,气管炎,哮喘,月经不调,神经衰弱。 For colds cough, bronchitis, asthma, irregular menstruation, neurasthenia.

[0018] 剪刀股为菊科苦卖菜属植物剪刀股Ixeris debilis A. Gray, W全草入药。 [0018] Scissors shares Asteraceae genus scissors bitter vegetables shares Ixeris debilis A. Gray, W whole plant medicine. 夏秋采收,鲜用或晒干。 Summer and autumn harvest, fresh or dried. 清热凉血,利尿消肿。 Heat and cooling, diuretic swelling. 用于肺热咳嗽,喉痛,口腔溃瘍,急性结膜炎,阔尾炎,水肿,小便不利;外用治乳腺炎,疮巧肿毒,皮肤瘦痒。 For Hyperactivity cough, sore throat, oral ulcers, acute conjunctivitis, broad tail inflammation, edema, urination; topical treatment of mastitis, Qiao sore swollen poison, thin skin itching.

[0019] 鸭公青为鼠李科勾儿茶属植物云南勾儿茶Berchemia yunnanensis Rranch.,W 根、叶入药。 [0019] duck male green as buckthorn plants Berchemia Yunnan Berchemia Berchemia yunnanensis Rranch., W roots, leaves used as medicine. 秋采根,夏采叶,晒干,清热利湿,巧风活络,活血止痛。 Autumn mining roots, summer leaf collection, dried, heat and dampness, wind clever active, promoting blood circulation and relieve pain. 用于黄痘,肾炎水肿,痴疾,红崩,白带,风湿骨痛,痛经;外用治骨折,跌打损伤,痛肿疮毒。 For yellow pox, nephritis, edema, crazy disease, red collapse, vaginal discharge, rheumatic pain, dysmenorrhea; topical treatment of fractures, traumatic injury, pain and swelling sore. 本发明W全草入药。 W whole plant medicine of the present invention.

[0020] 离根香为草海桐科离根香属植物离根香化Iogyne pilosa R. Brown, W全草入药。 [0020] from incense sticks to goodeniaceae from incense sticks incense plants from the root of Iogyne pilosa R. Brown, W whole plant medicine. 夏秋采,晒干。 Summer and collected and dried. 活血散癒,止痛,解毒。 Blood scattered healing, pain relief, detoxification. 用于跌打损伤,蛇咬伤。 For bruises, snake bites.

[0021] 凉粉草为唇形科植物,茎下部伏地,上部直立,叶卵形或卵状长圆形,先端稍纯,基部渐收缩成柄,边缘有小银齿,两面均有疏长毛;着生于花序上部的叶较小,呈巷片状,卵形至倒H角形,较花短,基部常带淡紫色,结果时脱落。 [0021] Grass jelly Labiatae, lower stem prostrate, upper upright, oblong or ovate leaves, apex slightly pure, gradually shrink into handle base, the edge of a small silver teeth, two long hairs are sparse ; inflorescence was born in an upper portion of the smaller leaves, Lane flake form, oval to angular inverted H, spend relatively short, often with the base lavender, off results. 总状花序柔弱,花小,轮生,弯小,钟状, 2唇形,上唇3裂,下唇全缘,结果时或筒状,下弯,有纵脉及横皱纹;花冠淡红色,上唇阔,全缘或齿裂,下唇长楠圆形,凹陷;雄蕊4,花丝突出;雌蕊1,花柱2裂;花盘一边膨大。 Raceme weak, small flowers, whorled, small curved, bell-shaped, two-lipped, the upper lip 3-lobed, entire lower lip, when the result or cylindrical, recurved, veins with longitudinal and transverse wrinkles; corolla pink, upper lip width, entire or cracked teeth, Nan circular lip length, the recess; stamens 4, projecting filaments; pistil 1, style 2 lobed; faceplate side inflated. 小坚果楠圆形。 Nutlets Nan circular. 花期秋季末。 Flowering late autumn. 分布我国南部。 Distribution south of the country. 拉下学名为Mesona chinensis Benth.,清热利湿, 凉血解暑。 Pull down the scientific name Mesona chinensis Benth., Heat and dampness, cooling hot weather. 用于急性风湿性关节炎,高血压,中暑,感冒,黄痘,急性肾炎,糖尿病。 For acute rheumatic arthritis, hypertension, heat stroke, cold, yellow pox, acute nephritis, diabetes. 本发明W 全草入药。 W whole plant medicine of the present invention.

[0022] 骆驼蹄瓣为裝黎科霸王属植物豆叶霸王巧肖〇地如1皿f油ago L,W根入药。 [0022] Camel hoof lobes mounted genus Chenopodiaceae King King clever bean leaves 1 Shaw square as the oil pan f ago L, W root medicine. 夏秋采挖,晒干或蜜炙。 Summer and autumn excavation, dried or honey roast. 止咳巧姨,止痛消炎。 Cough clever aunt, anti-inflammatory pain. 用于支气管炎,感冒,牙痛,顽固性头痛。 For bronchitis, colds, toothache, intractable headache.

[0023] 星色草为石竹科白鼓钉属植物白鼓钉化Iyca巧aea corymbosa Lam.的全草。 [0023] Star marigold color white white drum drum Caryophyllaceae staple of Iyca clever aea corymbosa Lam. The whole plant. 春秋采集,洗净晒干。 Spring collection, washed and dried. 清热解毒,除湿利尿。 Detoxification, dehumidification diuretic. 用于急性细菌性痴疾,肠炎,实症腹水,消化不良。 Crazy for acute bacterial disease, enteritis, ascites real disease, indigestion. 本发明W全草入药。 W whole plant medicine of the present invention.

[0024] 金叶子为杜酶花科植物云南假木荷的叶。 [0024] Ye Jin Du enzyme flower foliage plants for the wood false charge of Yunnan. 散癒止痛,巧风除湿,止血通菌。 Scattered more pain, Qiao wind and dampness, fungus through the hemostasis. 用于跌打损伤,外伤性昏迷,扭挫伤,腰腿痛,半身不遂,痛疾,风湿性关节炎,外伤出血,骨折。 For bruises, traumatic coma, contusion, back pain, hemiplegia, pain disease, rheumatoid arthritis, traumatic bleeding, fractures.

[00巧]转也莲为西番莲科西番莲属植物西番莲化SSiflora caerulea L,W根、藤和果入药。 [00 clever] Lin also turn into passionflower Passiflora species of Passiflora SSiflora caerulea L, W roots, vines and fruit used as medicine. 秋季果实成熟时采集,晒干;再采根、藤,分别晒干。 Mature fruit collected in autumn, dried; resampling roots, vines were dried. 巧风除湿,活血止痛。 Qiao wind and dampness, promoting blood circulation and relieve pain. 用于风湿骨痛,疵痛,痛经;外用治骨折。 For rheumatism, defects pain, dysmenorrhea; topical treatment of fractures. 本发明W根入药。 The present invention W root medicine.

[0026] 有益效果:本发明制得的药物能够安全有效治疗慢性膜腺炎。 [0026] Advantageous Effects: The present invention can be made effective and safe drug treatment of chronic pancreatitis.

具体实施方式 Detailed ways

[0027] W下通过实施例形式,对本发明的上述内容再作进一步的详细说明,但不应将此理解为本发明上述主题的范围仅限于W下的实例,凡基于本发明上述内容所实现的技术均属于本发明的范围。 [0027] W by the forms of embodiment, the above-described present invention will be further described in detail again, but this should not be understood that the above subject of the present invention is limited to the range W in the example, where the present invention is based on the realization techniques are within the scope of the present invention.

[002引1、具体实施例1 ;称取云南长菊宦苔13g、苍白称钩风14g、野胡麻lOg、纯叶楼梯草12g、小花柳叶菜16g、绿豆升麻12g、短瓣花14g、随手香16g、渥稿树12g、蛇见怕15g、排草香12g、剪刀股14g、鸭公青8g、离根香16g、凉粉草13g、骆驼蹄瓣12g、星色草lOg、金叶子12g、转也莲14g,加10倍量水,煎煮2小时,过滤;滤渣加8倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥,装入胶囊壳,即得符合正常成人1天用量的胶囊剂。 [1 lead 002, a particular embodiment 1; Weigh Yunnan Ju Huan long moss 13g, 14g pale said hook wind, wild flax lOg, pure grass leaves stairs 12g, Epilobium parviflorum 16g, green beans Cimicifuga 12g, 14g short petals to hand Hong 16g, Ottawa art tree 12g, a snake or fear 15g, ranked grassy 12g, scissors stocks 14g, duck male green 8g, from incense sticks 16g, grass jelly 13g, camel hoof valve 12g, satellite color grass lOg, gold leaf 12g , Lin also turn 14g, plus 10 times the amount of water, boiling for 2 hours, filtered; residues 8 times the amount of water, boiling for 1 hour and filtered; the filtrate were combined, concentrated and dried, filled into capsule shells, that was in line with normal adults 1 day dosage capsule. 用于治疗慢性膜腺炎。 For the treatment of chronic pancreatitis. 口服,每日分早晚两次服用。 Oral, daily morning and evening doses.

[0029] 2、具体实施例2 ;称取云南长菊宦苔13g、苍白称钩风14g、野胡麻lOg、纯叶楼梯草12g、小花柳叶菜16g、绿豆升麻12g、短瓣花14g、随手香16g、渥稿树12g、蛇见怕15g、排草香12g、剪刀股14g、鸭公青8g、离根香16g、凉粉草13g、骆驼蹄瓣12g、星色草lOg、金叶子12g、转也莲14g,加10倍量水,煎煮2小时,过滤;滤渣加8倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥,加淀粉,按常规工艺制粒,即得符合正常成人1天用量的颗粒剂。 [0029] 2, the specific embodiment 2; Weigh Yunnan Ju Huan long moss 13g, 14g pale said hook wind, wild flax lOg, pure grass leaves stairs 12g, Epilobium parviflorum 16g, green beans Cimicifuga 12g, 14g short petals to hand Hong 16g, Ottawa art tree 12g, a snake or fear 15g, ranked grassy 12g, scissors stocks 14g, duck male green 8g, from incense sticks 16g, grass jelly 13g, camel hoof valve 12g, satellite color grass lOg, gold leaf 12g , Lin also turn 14g, plus 10 times the amount of water, boiling for 2 hours, filtered; residues 8 times the amount of water, boiling for 1 hour and filtered; the filtrate were combined, concentrated and dried, add starch, granulated by a conventional process, i.e., granules obtained in line with normal adult dosage of one day. 用于治疗慢性膜腺炎。 For the treatment of chronic pancreatitis. 口服,每日分早晚两次服用。 Oral, daily morning and evening doses.

[0030] 3、具体实施例3 ;称取云南长菊宦苔13g、苍白称钩风14g、野胡麻lOg、纯叶楼梯草12g、小花柳叶菜16g、绿豆升麻12g、短瓣花14g、随手香16g、渥稿树12g、蛇见怕15g、排草香12g、剪刀股14g、鸭公青8g、离根香16g、凉粉草13g、骆驼蹄瓣12g、星色草lOg、金叶子12g、转也莲14g,加10倍量水,煎煮2小时,过滤;滤渣加8倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥,加淀粉,按常规工艺制粒,压片,即可制得符合正常成人1天用量的片剂。 [0030] 3. The Specific Example 3; Weigh Yunnan Ju Huan long moss 13g, 14g pale said hook wind, wild flax lOg, pure grass leaves stairs 12g, Epilobium parviflorum 16g, green beans Cimicifuga 12g, 14g short petals to hand Hong 16g, Ottawa art tree 12g, a snake or fear 15g, ranked grassy 12g, scissors stocks 14g, duck male green 8g, from incense sticks 16g, grass jelly 13g, camel hoof valve 12g, satellite color grass lOg, gold leaf 12g , Lin also turn 14g, plus 10 times the amount of water, boiling for 2 hours, filtered; residues 8 times the amount of water, boiling for 1 hour and filtered; the filtrate were combined, concentrated and dried, add starch, according to the conventional process granulating, tablets, can be prepared one day in line with normal adult dosage tablet. 用于治疗慢性膜腺炎。 For the treatment of chronic pancreatitis. 口服,每日分早晚两次服用。 Oral, daily morning and evening doses.

[0031] 4.本发明对慢性膜腺炎的临床研究 Clinical studies of chronic pancreatitis [0031] 4. The present invention

[0032] 4. 1、一般资料;发明人2010年8月-2012年12月间共收集70例慢性膜腺炎的口诊患者,年龄37-57岁,病程1-4年。 [0032] 4.1 General Information; August 2010 Inventors - between December 2012 were 70 patients diagnosed with chronic pancreatitis mouth patients, aged 37-57 years, duration of 1 - 4 years. 随机分为;治疗组40例,空白组30例。 Randomly divided; treatment group 30 cases 40 cases control group. 两组年龄、病情等资料无显著性差异,具有可比性。 There was no significant difference between the two groups of age, illness, etc., comparable.

[0033] 诊断标准;(1)腹部B ;超膜腺组织内有膜石存在。 [0033] The diagnostic criteria; (1) abdominal B; the presence of the super-film membrane gland stone. (2)CT ;膜腺内巧化,证实有膜石。 (2) CT; Qiao gland of the film, the film confirmed stone. (3化RCP ;膜腺组织内膜管及其分支不规则扩张并且分布不均匀;主膜管部分或完全阻塞,含有膜石或蛋白栓子。(4)分泌试验;重碳酸盐分泌减少,伴膜酶分泌或排出量降低。 (5)组织学检查;组织切片可见膜腺外分泌组织破坏、减少,小叶间有片状不规则的纤维化,但小叶间纤维化并非慢性膜腺炎所特有。(6)导管上皮增生或不典型增生、囊肿形成。 (3 of the RCP; endometrial glands film tube expansion and branched irregularly and uneven distribution; main film tube partially or completely blocked, or egg Bai Shuanzai film containing stone (4) secretion test;. Reduced secretion of bicarbonate , an enzyme secreted or membrane with reduced discharge amount (5) histology;. tissue section showed outer membrane gland tissue destruction, reduce, sheet-like irregular interlobular fibrosis, fibrosis interlobular but not the chronic pancreatitis specific. (6) ductal hyperplasia or atypical hyperplasia, cyst formation.

[0034] 4. 2、试验方法 [0034] 4.2 Experimental Method

[00巧]4.2. 1治疗组口服本发明按照具体实施例1制得的胶囊,早晚各一次。 [Qiao 00] 4.2. 1 treatment group was treated in accordance with the present invention a particular embodiment the capsule prepared, morning and evening. 疗程15天。 Course of 15 days.

[0036] 4. 2. 2空白组口服安慰剂胶囊,早晚各一次。 [0036] 4.2.2 oral placebo control group capsules morning and evening. 疗程15天。 Course of 15 days.

[0037] 4. 3、疗效标准与治疗结果 [0037] 4.3, with the standard efficacy of treatment outcome

[0038] 4. 3. 1疗效标准 [0038] 4. The efficacy of the standard 3.1

[0039] 痊愈;临床症状全部消失,试验室检查正常。 [0039] healed; clinical symptoms disappeared, laboratory examination was normal. 好转;临床症状减轻,病情得到控制, 实验室检查改善或正常。 Improved; clinical symptoms, the condition under control, to improve laboratory tests or normal. 无效:临床症状无明显好转或加重。 Invalid: no significant improvement in clinical symptoms or worsen.

[0040] 4. 3. 2治疗统计结果见表1。 [0040] 4.3.2 Treatment statistical results are shown in Table 1.

[00川表1两组疗效比较 [1 were compared the efficacy of Sichuan Table 00

[0042] [0042]

Figure CN104225111AD00061

[0043] 可见,本发明制得的药物能够安全有效治疗慢性膜腺炎。 [0043] it is seen that the present invention can be made effective and safe drug treatment of chronic pancreatitis.

Figure CN104225111AD00062

Claims (2)

1. 一种治疗慢性胰腺炎的中药组合物,其特征在于,它由如下重量份数的原料制备得至|J :云南长蒴苣苔13份、苍白称钩风14份、野胡麻10份、钝叶楼梯草12份、小花柳叶菜16 份、绿豆升麻12份、短瓣花14份、随手香16份、潺槁树12份、蛇见怕15份、排草香12份、 剪刀股14份、鸭公青8份、离根香16份、凉粉草13份、骆驼蹄瓣12份、星色草10份、金叶子12份、转心莲14份。 1. A method of treating chronic pancreatitis Chinese medicine composition, characterized in that it is prepared from the following raw materials in parts by weight to obtain | J: long Yunnan capsule Gesneriaceae 13 parts, said hooks pale wind 14 parts, 10 parts of wild flax , blunt leaf grass stairs 12 parts, 16 parts of Epilobium flowers, green beans cohosh 12 copies, 14 copies short flower petals, fragrant hand 16 parts, 12 parts of trickle withered tree, a snake or a fear of 15 parts, 12 parts grassy row, scissors shares of 14, male duck green 8 parts, 16 parts from incense sticks, grass jelly 13 parts, camel hoof flap 12 parts, 10 parts of star grass color, 12 parts of gold leaf, lotus heart turn 14 copies.
2. 如权利要求1所述治疗慢性胰腺炎的中药组合物在治疗慢性胰腺炎的药物中的应用。 The treatment of chronic pancreatitis a traditional Chinese medicine composition used in the treatment of chronic pancreatitis as claimed in claim 2.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005053818A (en) * 2003-08-01 2005-03-03 Yakult Honsha Co Ltd Trypsin inhibitor
CN1698754A (en) * 2005-05-16 2005-11-23 赵正夫 Medicine for treating acute and chronic pancreatitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005053818A (en) * 2003-08-01 2005-03-03 Yakult Honsha Co Ltd Trypsin inhibitor
CN1698754A (en) * 2005-05-16 2005-11-23 赵正夫 Medicine for treating acute and chronic pancreatitis

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* Cited by examiner, † Cited by third party
Title
刘启廷等: "《常见病一方通用经验方》", 30 April 2013, 中医古籍出版社 *

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