CN104224598A - Infant mosquito repellent containing folium artemisiae argyi extract - Google Patents

Infant mosquito repellent containing folium artemisiae argyi extract Download PDF

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CN104224598A
CN104224598A CN201310249535.8A CN201310249535A CN104224598A CN 104224598 A CN104224598 A CN 104224598A CN 201310249535 A CN201310249535 A CN 201310249535A CN 104224598 A CN104224598 A CN 104224598A
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extract
artemisiae argyi
folium artemisiae
mosquito repellent
cream
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CN201310249535.8A
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于丽霞
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Qingdao Daohe Biotechnology Co Ltd
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Qingdao Daohe Biotechnology Co Ltd
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Abstract

The invention discloses an infant mosquito repellent containing folium artemisiae argyi extract. Main ingredients of the infant mosquito repellent are folium artemisiae argyi extract essence, folium eucalypti extract essence, diphasiastrum complanatum extract, honeysuckle extract, wild chrysanthemum extract, elemi, mint, juniper berry extract and vitamin B. The infant mosquito repellent is formed by virtue as the process steps of mixing, soaking on an airtight condition, stirring, extracting and purifying. The infant mosquito repellent is compounded of essences extracted from pure natural plants; the extracted folium artemisiae argyi having extremely good mosquito repelling effect for babies is mixed with the folium eucalypti extract essence and diphasiastrum complanatum extract to strengthen the skin health of babies; the infant mosquito repellent is cool, capable of removing toxins and protecting babies from being bitten by mosquitoes, and thus the infant mosquito repellent is especially suitable for newborn infants, is capable of calming mind and preventing various skin discomforts, and is also suitable for pregnants and lying-in women.

Description

Folium Artemisiae Argyi skims the cream off milk the anti-mosquito bite agent of plain infant
technical fieldthe present invention relates to a kind of Folium Artemisiae Argyi to skim the cream off milk the anti-mosquito bite agent of plain infant, its main component is that skim the cream off milk liquid, Folium eucalypti globueli (Eucalyptus globulus Labill.) of Folium Artemisiae Argyi skims the cream off milk liquid, flat loose extract, Flos Lonicerae extract, Flos Chrysanthemi Indici extract, Canarium luzonicum Elemi, Herba Menthae, gin extract, vitamin B1; Form through techniques such as mixing, sealing immersion, stirring, extraction, purifications.Composite owing to being the essence that pure natural plant extracts, have the anti-mosquito bite of infant and very extract Folium Artemisiae Argyi essence, merge Folium eucalypti globueli (Eucalyptus globulus Labill.) to skim the cream off milk liquid, flat loose extract, promote baby's skin health, refrigerant detoxification is anti-to be bitten, and be particularly suitable for newborn baby and use, calmness is releived, prevention link various skin is uncomfortable, and the same pregnant and lying-in women of being applicable to use.
background technologyin summer, band baby go out and have a breath of fresh air and is afraid of have mosquito to sting him, and looked into one logical how to baby's anophelifuge on the net, it is suitable still not find, is everybody what way? is baby Jinsui River handy? there is Folium Artemisiae Argyi, Herba Pogostemonis, Herba Eupatorii, Flos Caryophylli, Rhizoma Acori Graminei, Fructus Amomi Rotundus, Herba Asari, Flos Magnoliae, Pericarpium Citri Reticulatae, Flos Chrysanthemi, Rhizoma Chuanxiong, Rhizoma Atractylodis etc., except Folium Artemisiae Argyi is not smashed to pieces, other will the people of pharmacy help us to smash to pieces when buying, mixing of then putting together.General every sample 6-10 gram, price is very cheap.Effect is antiviral, flu-prevention, mosquito dispersing, damp eliminating gas, righting gas, refreshment.Chinese medicine is our quintessence of Chinese culture, and in several thousand that do not have mosquito incense insecticide, our ancestor comes healthy estivate, very environmental protection by these methods.Way is also very simple, bring and give friend, particularly child, hang over room, it is all effectively what mosquito-proof circle said and so on the net of feeling, all poisonous, not so how mosquito can be arrived by poison, last time, the knowledge received on mobile phone in a life said that these mosquito-proof toxicity seldom can not jeopardize our human body, but I does not advocate baby and preferably hangs mosquito net to baby exactly with these, otherwise to be coated on the skin exposed also passable to baby with the aqueous solution of some vitamin B1, mosquito does not like the taste weather of vitamin B1 more and more hotter, arrive again the mosquito rampant movable time.In this time, the little soft textive that babies are smooth has just become the favourite of mosquitoes.Tender and lovely skin can be left the red packet bag of very itching incomparable after mosquito bite, allow baby's misery also allow mother love.The expert of Affiliated Hospital of Hunan University of Traditional Chinese Medicine and Xiang Ya hospital recommends several convenience mosquito-proof method practical again to reader here: one, have a bath with anise.Go in the seasoning pot in kitchen, to find out anistree two pieces, steep in warm water washbowl.Mother baby can with this basin washing bath, and fragrance light with it after washing is just as added one invisible protective cover, and mosquito again dare not near body.Two, residual Folium Camelliae sinensis is except mosquito.If you are a person who is ambitious or tenacious of purpose, that is just collected and drinks surplus residual Folium Camelliae sinensis at ordinary times, the place burning that just easily can pass in and out mosquito after being dried, driving away mosquito.Or the Folium Artemisiae Argyi etc. of drying in the shade is twisted into rope, is placed on indoor after lighting, its smoke equally can anophelifuge.Three, Chinese red bulb is installed.Indoor location Chinese red bulb, because mosquito fears the light of Chinese red, so can produce good repelling effect.If do not have Chinese red bulb, also can be enclosed within the bulb of 60 watts with the Exocarpium Citri Rubrum cellophane that light transmission is strong, mosquito can become separated in flight everywhere.Four, fragrant wood flour anophelifuge.Some are had the wood flour of fragranced, be placed in iron flask, wood flour is put several pieces and burns red charcoal, then put some dry Citrus, orange or pomelo peels on the whole, can give out ferocious abnormal smells from the patient after burning, mosquito smells will " keep a good distance from ".Five, Herba Menthae is smeared.Get the leaf of several Herba Menthaes, Folium Perillae or Fructus Lycopersici esculenti, rub out juice and be applied on the exposed skin of health, mosquito smells the special odor that these plant juices come out, and that is in fear of to keep away is too late.Six, fancy soap water kill mosquito ovum.Put a basin at balcony, put the suds that fancy soap and detergent are made in basin, can lay eggs in water by attracting mosquitoes.The environment of this alkalescence is not suitable for mosquito existence, a few days therefore, will be covered with the immature mosquito ovum of much death in basin.Expert also reminds reader, have a bath to baby with fancy soap less.Because mosquito eating nectar reveals, if use the article of the band flowery odours such as perfume, cosmetics, facial cream, mosquito will hear perfume (or spice).But, and the fragrance of not all can cause mosquito, and culicifuge incense water-band Lignum Santali Albi taste as special in baby, can play anophelifuge.Want many and eat vegetable to baby.The abnormal smells from the patient having some to contain mosquito in vegetable not like, as there being the vegetable etc. of acid containing the vegetable of carotene and Bulbus Allii etc., after baby eats, mosquito also can from his far point, the garlic flavour that mosquito does not like human secretory to go out.These helpless behaves make microorganism and mosquito in room air a bit not reduce.Generally human body sends out that bacterium amount is per minute is less than 1000, but the Excreta of patient and secretions are containing a large amount of pathogen, can severe contamination air, and air pollution must cause carbon dioxide to increase, and provides the source of assembling and growing to mosquito.Special in recent years, along with parasite killing mosquitocide, and increasing of using of various mosquito incense, too increase the chance that air toxic pollutes simultaneously.The disease caused by air toxic is comparatively serious respiratory tract disease.Therefore, the preparation that the sterilization mosquito proof utilizing plant extraction liquid to prepare various infant is bitten highly significant.The Folium Artemisiae Argyi plain infant anti-mosquito bite agent that skims the cream off milk can be used for the child at various skin, each age.The object of the present invention is to provide one can overcome existing procucts deficiency, have that antibacterial mosquito proof bites that efficiency is high, good stability, high to infant nonhazardous, environmentally safe, security performance, and the Folium Artemisiae Argyi of the feature such as dispelling abnormal flavor to skim the cream off milk the anti-mosquito bite agent of plain infant.
summary of the inventionmain points of the present invention are to select suitable component, and carry out rational mixture, form Folium Artemisiae Argyi to skim the cream off milk the anti-mosquito bite agent of plain infant through techniques such as mixing, sealing immersion, stirring, extraction, purifications.
The formula that the present invention selects is following (component and percentage by weight % thereof): Folium Artemisiae Argyi skims the cream off milk liquid 4.0-6.0; Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk liquid 2.0-6.0; Flat loose extract 2.0-6.0; Flos Lonicerae extract 2.0-6.0; Flos Chrysanthemi Indici extract 2.0-6.0; Canarium luzonicum Elemi 2.0-6.0; Herba Menthae 2.0-6.0; Gin extract 2.0-6.0; Vitamin B12 .0-6.0; Clean water adds to 100.
Folium Artemisiae Argyi skims the cream off milk, first the extracting method of quintessence oil have multiple, as vapor distillation, squeezing, extraction etc. use steam distillation. first distill Folium Artemisiae Argyi and clear water mixture, mixed ratio is one to four, sodium chloride is added in the oil water mixture of then gained after distillation, then oil reservoir and water layer is separated with separatory funnel, finally add anhydrous sodium sulfate, system finishes.Folium Artemisiae Argyi enters in cauldron and boils after cleaning with clear water, adding a little soda powder therebetween together with boiling, Folium Artemisiae Argyi can be made so easily well-done, after cooked Folium Artemisiae Argyi, pulls out and cleans with clear water, then extract moisture for subsequent use.Folium Artemisiae Argyi quintessence oil is extracted by the elite extracted in Folium Artemisiae Argyi to form, and it coordinates moxa-moxibustion to use curative effect very remarkable.Natural Folium Artemisiae Argyi extracting refining forms, and outward appearance is pale yellow or green-yellow.Promoting the flow of QI in the collateral by warming the meridian, benefiting QI for activating blood circulation, cold-dispelling pain-relieving, improve local circulation, increase immunity, be coated on acupuncture point or affected part, repeatedly rub to absorption.
Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk, the eucalyptus oil of cineole content 80%: be the leaf with the Eucalyptus globulus Labill of steam distillation from China or some the Lignum cinnamomi camphorae kind containing cineole, the quintessence oil extracted in branch, again through cineole content that rectification processing is obtained minimum be 80% eucalyptus oil. 80% eucalyptus oil, divide by raw material sources that to have two kinds: a. Eucalyptus Globulus oil to be other quintessence oils of raw material b. be on the basis of the opposed polarity solvent extraction of raw material eucalyptus leaves and bioactivity research thereof, the insecticide active substance of the good Eucalyptus urophylla-grandis extract of insecticidal activity is extracted, be separated, qualification and insecticidal activity research, by showing its Antifeedant Effect Against of diamondback moth 3 instar larvae, with 95% ethanol for solvent, the antifeedant activity that ultrasonic assistant is extracted as extracting method extract obtained is the highest.When the concentration for the treatment of of Eucalyptus urophylla-grandis is 15mg/ml, 84.07%, 78.62% is respectively to the non-selective anti-food rate of diamondback moth 3 instar larvae 24h, 48h.3, biological activity determination has been carried out to six kinds of Folium eucalypti globueli (Eucalyptus globulus Labill.) 95% ethanol extractions.1. different Folium eucalypti globueli (Eucalyptus globulus Labill.) extract has certain stomach poison function to diamondback moth 2 instar larvae, and eucalyptus citriodora is when concentration 20mg/ml, 5d, and accumulated correction mortality rate reaches 70%, and in 6 kinds of Folium eucalypti globueli (Eucalyptus globulus Labill.) extracts, stomach poison function is the strongest.2. different Folium eucalypti globueli (Eucalyptus globulus Labill.) extract shows to diamondback moth adult avoidance effect of laying eggs preferably, and wherein the Oviposition Repellent of Alcohol Extracts of Eucalyptus urophylla-grandis is the strongest, and when concentration is 10mg/ml, selectivity scattering ratio is 63.67%, IIPC is 0.2222; Non-selection scattering ratio is that 80.34%, IIPC is respectively 0.1967.3. different Folium eucalypti globueli (Eucalyptus globulus Labill.) extract has stronger repellent and fumigation action to red flour beetle and sitophilus oryzae, wherein Eucalyptus urophylla-grandis shows good repellent action to red flour beetle and sitophilus oryzae, when concentration is 10mg/cm2, the scattering ratio of 24h is respectively 87.37%, 80.26%, and repellent grade is V level.The Eucalyptus urophylla-grandis of 32mg/L is fumigated 72h post-equalization mortality rate to rice weevil and red flour beetle adult and is respectively 85.05%, 48.88%.4, adopt liquid-liquid extraction to be separated Eucalyptus urophylla-grandis 95% ethanol extraction, Eucalyptus urophylla-grandis main active is at petroleum ether extraction layer.The anti-food rate of petroleum ether extract to diamondback moth 3 instar larvae 24h of 10mg/ml is 82.05%, and non-selective oviposition detterent rate is 63.67%; The petroleum ether extract of 10mg/cm2 is 88.18% to red flour beetle adult 72h scattering ratio, repellent grade V level.5, adopt silica gel column chromatography to be separated petroleum ether extract, find that main active is in L-2 component.The anti-food rate of component L-2 to diamondback moth 3 instar larvae 24h of 10mg/ml is the anti-food rate of 84.69%, 48h be 76.07%, AFC50 is 1.96mg/ml.The scattering ratio of component L-2 to red flour beetle adult 72h of 10mg/cm2 is 81.29%, repellent grade V level.6, the GC-MS technical Analysis chemical composition of Eucalyptus urophylla-grandis petroleum ether extraction layer and component L-2 is adopted.Main component is 1,8-cineole.
Flat loose extract: micro-have faint scent, mildly bitter flavor, micro-pungent., dark green tender with leaf is good without broken last person.Leaf containing volatile oil 0.6 ~ 1%, in containing thujene, absinthol, fenchone, pinene, caryophyllene etc.; Aromadendrin, Quercetin, myricetin, hinokiflavone, amentoflavone etc. are had in flavonoid.The rough general flavone content of new fresh Cacumen Platycladi is 1.72%.Also containing tannin, resin, vitamin C etc.Pharmacological action extract has antitussive, phlegm-dispelling functions to mice.Be separated its effective ingredient, contained alcoholic Saponin phlegm-dispelling functions is comparatively strong, and its antitussive composition may be a kind of phenol glycoside.Causing of Cavia porcellus to be breathed heavily without obvious protective effect (histamine's nebulization), but can diastole guinea-pig isolated tracheal smooth muscle, and can the effect of part blocks acetylcholine, that can not remove acetylcholine causes convulsion effect.Flavone 250 mgs/kg of lumbar injections contained in leaf have obvious antitussive effect, and 200 mgs/kg of lumbar injections and 1000 mgs/kg orally have obvious phlegm-dispelling functions.No. II, the live part extract in leaf (ethyl acetate extract) 250 mgs/kg of lumbar injections have obvious antitussive effect, and 100 and 200 mgs/kg have obvious phlegm-dispelling functions.Alcohol preserved material (1:180000) has inhibitory action to the growth of tubercule bacillus in test tube, and comparatively water decoction is strong 1800 times, and has synergism with different cigarette callosity.Inhibitory action is had to streptococcus pneumoniae, micrococcus catarrhalis.Cacumen Platycladi, serrate holly leaf compound recipe also have inhibitory action to the joyous coccus of pneumonia, hemophilus influenza, staphylococcus aureus, pneumobacillus and alpha streptococcus etc.Cacumen Platycladi decoct 1:40 has inhibitory action to capital section 68-1 type virus.Wherein contained absinthol is when it is to dosage (1 ~ 10 mg/kg) that animal is harmless, neither affect the spontaneous activity of rat, do not change the behavior (just making this kind of behavior more coordinate) learnt its day after tomorrow, very heavy dose ofly do not affect corticocerebral respiratory activity yet yet.Oral 60 gs/kg of white mice, observes 72 hours, and have no dead, lumbar injection water decoction median lethal dose(LD 50) is 15.2 gs/kg, and the preparation after water decoction alcohol precipitation is then 30.5 gs/kg, and toxicity is little.
Flos Lonicerae, has another name called Radix Ophiopogonis, Flos Lonicerae, Flos Lonicerae etc., is described as the good medicine of heat-clearing and toxic substances removing from ancient times.Its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Flos Chrysanthemi Indici extract Flos Chrysanthemi Indici extracting solution effective ingredient: containing volatile oil 01% ~ 0.2%, containing chrysol (chrysol), chrysanthone (chrysantone) in oil, still containing dl-Camphora, β-3-carene (β-3-carene), sabinene (sabinene) and cephrol (carvol).In addition, yejuhua lactone (yejuhualactone) about 0.1% is separated to obtain in spending, Flos Buddlejae glycoside (acacetin-7-rhamnoglucoside) about 0.72%. is separately containing luteolin glycoside (luteolin glucoside), red glycoside (the chrysanthemin of chrysanthemum, asterin) chrysanthemaxanthin (chrysanthemaxanthin), epoxy phylloxanthin (xanthophyllepoxide), luteolin, Flos Chrysanthemi Indici ketone (bisabolane ketone glycol), and chrysanthemol, daucosterol, ambrosin, acacetin, mountain Yu's acid glyceride, Palmic acids etc. have anti-bacteria and anti-virus, heat clearing and inflammation relieving, antioxidation prevention skin aging.Ramulus et Folium Spiraeae Salicifolia elite triple effect disobeys orders composition, suppress 5a-reductase active convergence pore reduce oils and fats.
Canarium luzonicum Elemi, Herba Menthae, gin extract, vitamin B1 are the antibacterial of All Pure Nature wide spectrum.In this component any one folk prescription time all can not kill antibacterial on skin and spore, can not dispelling abnormal flavor.After being mixed in proportion into compound recipe, by its synergism, antibacterial and spore can not only be killed, also can dispelling abnormal flavor, substantially increase sterilization effect.Containing Multiple components in compound product, the content ratio of each single component reduces relatively, therefore, also few to side effect such as the toxicity of people and zests.Therefore, have nontoxic non-stimulated to infant, and can the activity of killing microorganisms, antiinflammatory, antibacterial, purify air, air refreshing in dispelling odor, holding chamber, make the effects such as people's spirit is brisk and neat.
The preparation method of product of the present invention is:
1) Folium Artemisiae Argyi is skimmed the cream off milk, Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk, flat loose extract, Flos Lonicerae extract, Flos Chrysanthemi Indici extract, Canarium luzonicum Elemi, Herba Menthae, gin extract, vitamin B1, to mix by proportioning;
2) clean water carries out sealing immersion;
3) under slowly stirring, extract, purify, subpackage.
The present invention has the following advantages: the child 1) being suitable for various skin, each age; 2) pure natural preparation has high efficiency antibacterial mosquito proof and bites effect; 3) good stability, high to infant nonhazardous, environmentally safe, security performance; 4) energy dispelling abnormal flavor, is renewal product.
detailed description of the inventionbelow in conjunction with embodiment, the present invention is described in further detail:
Be configured according to 100 kilograms of data (percentage by weight %) and described step thereof:
Formula:
Folium Artemisiae Argyi skims the cream off milk liquid 4.0-6.0; Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk liquid 2.0-6.0; Flat loose extract 2.0-6.0; Flos Lonicerae extract 2.0-6.0; Flos Chrysanthemi Indici extract 2.0-6.0; Canarium luzonicum Elemi 2.0-6.0; Herba Menthae 2.0-6.0; Gin extract 2.0-6.0; Vitamin B12 .0-6.0; Clean water adds to 100.
Technique:
1) Folium Artemisiae Argyi is skimmed the cream off milk, Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk, flat loose extract, Flos Lonicerae extract, Flos Chrysanthemi Indici extract, Canarium luzonicum Elemi, Herba Menthae, gin extract, vitamin B1, to mix by proportioning;
2) clean water carries out sealing immersion;
3) under slowly stirring, extract, purify, subpackage.

Claims (2)

1. the present invention relates to a kind of Folium Artemisiae Argyi to skim the cream off milk the anti-mosquito bite agent of plain infant; It is characterized in that having following formula (component and percentage by weight % thereof) Folium Artemisiae Argyi to skim the cream off milk liquid 4.0-6.0; Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk liquid 2.0-6.0; Flat loose extract 2.0-6.0; Flos Lonicerae extract 2.0-6.0; Flos Chrysanthemi Indici extract 2.0-6.0; Canarium luzonicum Elemi 2.0-6.0; Herba Menthae 2.0-6.0; Gin extract 2.0-6.0; Vitamin B12 .0-6.0; Clean water adds to 100.
2. Folium Artemisiae Argyi described in claim 1 skims the cream off milk the anti-mosquito bite agent of plain infant, it is characterized in that having following step:
1) Folium Artemisiae Argyi is skimmed the cream off milk, Folium eucalypti globueli (Eucalyptus globulus Labill.) skims the cream off milk, flat loose extract, Flos Lonicerae extract, Flos Chrysanthemi Indici extract, Canarium luzonicum Elemi, Herba Menthae, gin extract, vitamin B1, to mix by proportioning;
2) clean water carries out sealing immersion;
3) under slowly stirring, extract, purify, subpackage.
CN201310249535.8A 2013-06-23 2013-06-23 Infant mosquito repellent containing folium artemisiae argyi extract Pending CN104224598A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105284956A (en) * 2015-11-20 2016-02-03 陈倚华 Chinese herbal liquid mosquito-repellent incense and preparation method thereof
CN105901124A (en) * 2016-04-21 2016-08-31 黄志亮 Insect prevention composite, insect prevention agent containing same, and application of the insect prevention agent
CN106032078A (en) * 2016-05-13 2016-10-19 芜湖三刀材料科技有限公司 Composite fabric
CN106137855A (en) * 2016-08-17 2016-11-23 朱维 A kind of natural infant mosquito-driving liquid containing Thallus Porphyrae extract

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105284956A (en) * 2015-11-20 2016-02-03 陈倚华 Chinese herbal liquid mosquito-repellent incense and preparation method thereof
CN105901124A (en) * 2016-04-21 2016-08-31 黄志亮 Insect prevention composite, insect prevention agent containing same, and application of the insect prevention agent
CN106032078A (en) * 2016-05-13 2016-10-19 芜湖三刀材料科技有限公司 Composite fabric
CN106137855A (en) * 2016-08-17 2016-11-23 朱维 A kind of natural infant mosquito-driving liquid containing Thallus Porphyrae extract

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Application publication date: 20141224