CN104161795A - Soft capsule with functions of calming and impatience inhibition and preparation method of soft capsule - Google Patents
Soft capsule with functions of calming and impatience inhibition and preparation method of soft capsule Download PDFInfo
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- CN104161795A CN104161795A CN201410423782.XA CN201410423782A CN104161795A CN 104161795 A CN104161795 A CN 104161795A CN 201410423782 A CN201410423782 A CN 201410423782A CN 104161795 A CN104161795 A CN 104161795A
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- herba ocimi
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- lavandula angustifolia
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- 239000007901 soft capsule Substances 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 206010049976 Impatience Diseases 0.000 title description 6
- 230000001914 calming effect Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 244000178870 Lavandula angustifolia Species 0.000 claims abstract description 45
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims abstract description 45
- 238000000194 supercritical-fluid extraction Methods 0.000 claims abstract description 28
- 239000000843 powder Substances 0.000 claims abstract description 18
- 239000008157 edible vegetable oil Substances 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims abstract description 13
- 239000010692 aromatic oil Substances 0.000 claims abstract description 7
- 239000003921 oil Substances 0.000 claims description 22
- 235000019198 oils Nutrition 0.000 claims description 22
- 230000000694 effects Effects 0.000 claims description 21
- 239000000284 extract Substances 0.000 claims description 20
- 238000002203 pretreatment Methods 0.000 claims description 12
- 239000004006 olive oil Substances 0.000 claims description 10
- 235000008390 olive oil Nutrition 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 8
- 239000000341 volatile oil Substances 0.000 claims description 7
- 239000012567 medical material Substances 0.000 claims description 6
- 238000012545 processing Methods 0.000 claims description 6
- 235000003935 Hippophae Nutrition 0.000 claims description 4
- 241000229143 Hippophae Species 0.000 claims description 4
- 240000008415 Lactuca sativa Species 0.000 claims description 4
- 150000002333 glycines Chemical class 0.000 claims description 4
- 235000012045 salad Nutrition 0.000 claims description 4
- 239000003814 drug Substances 0.000 abstract description 7
- 208000019901 Anxiety disease Diseases 0.000 abstract description 6
- 230000036506 anxiety Effects 0.000 abstract description 6
- 238000000605 extraction Methods 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 abstract description 2
- 241001529734 Ocimum Species 0.000 abstract 4
- 235000010676 Ocimum basilicum Nutrition 0.000 abstract 4
- 239000001102 lavandula vera Substances 0.000 abstract 4
- 235000018219 lavender Nutrition 0.000 abstract 4
- 230000000049 anti-anxiety effect Effects 0.000 abstract 3
- 239000000932 sedative agent Substances 0.000 abstract 3
- 230000001624 sedative effect Effects 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 239000003205 fragrance Substances 0.000 description 7
- 206010026749 Mania Diseases 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 2
- 230000002180 anti-stress Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000002557 soporific effect Effects 0.000 description 2
- 230000002936 tranquilizing effect Effects 0.000 description 2
- 241000700199 Cavia porcellus Species 0.000 description 1
- OMFXVFTZEKFJBZ-UHFFFAOYSA-N Corticosterone Natural products O=C1CCC2(C)C3C(O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 OMFXVFTZEKFJBZ-UHFFFAOYSA-N 0.000 description 1
- 208000020401 Depressive disease Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241001579180 Matthiola longipetala Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 230000001430 anti-depressive effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 239000000935 antidepressant agent Substances 0.000 description 1
- 229940005513 antidepressants Drugs 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000000164 antipsychotic agent Substances 0.000 description 1
- 229940005529 antipsychotics Drugs 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000004820 blood count Methods 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- OMFXVFTZEKFJBZ-HJTSIMOOSA-N corticosterone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@H](CC4)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OMFXVFTZEKFJBZ-HJTSIMOOSA-N 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 description 1
- 229910052808 lithium carbonate Inorganic materials 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 230000002969 morbid Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种具有镇静抗焦躁作用的软胶囊及其制备方法，属于医药领域。包括薰衣草和罗勒的前处理，采用CO2超临界萃取方法从薰衣草和罗勒中提取芳香油：按重量份将薰衣草粗粉140~160份、罗勒粗粉60~80份装入CO2超临界萃取罐中，以压力为24~28MPa，温度为45℃~55℃的条件下进行萃取120~200分钟，CO2流量为10~20L/h；制成软胶囊。优点是，通过CO2超临界萃取技术从薰衣草和罗勒中提取出具有镇静抗焦躁的有效成分，并且将其与食用油混合制成具有镇静、抗焦躁作用的软胶囊，为广大焦躁症患者提供的了有效的药物。The invention relates to a soft capsule with sedative and anti-anxiety effects and a preparation method thereof, belonging to the field of medicine. Including the pretreatment of lavender and basil, using CO2 supercritical extraction method to extract aromatic oil from lavender and basil: put 140~160 parts of lavender coarse powder and 60~80 parts of basil coarse powder into CO2 supercritical extraction In the tank, the extraction is carried out for 120-200 minutes under the conditions of a pressure of 24-28MPa and a temperature of 45-55°C, and a CO2 flow rate of 10-20L/h; it is made into a soft capsule. The advantage is that the sedative and anti-anxiety active ingredients are extracted from lavender and basil through CO 2 supercritical extraction technology, and mixed with edible oil to make soft capsules with sedative and anti-anxiety effects, which provide the majority of anxiety patients with of effective drugs.
Description
Technical field
The present invention relates to medical technical field, specifically pass through CO
2supercritical extraction technique extracts the effective ingredient with calm anti-impatience from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), and itself and edible oil are mixed and made into soft capsule.
Background technology
Along with the continuous progress of economy, people's life is also in continuous change, the a lot of people of contemporary society especially white-collar job person are in the environment of pressure, for a long time pressure not only can cause that over-burden at heart, also can allow people in sub-health state, increasing people occurs that the manic state of anxiety can not extricate oneself eventually.Impatience is that desire is subject to constraining neurasthenic whole that forms, and normally, due to too conscientious, inter personal contact is not good, and easily self-isolation, is stimulated by other people words and deeds, in daily life in the tight state of spirit, is triggered at any moment with other people contention of mouth and tongue.
The manic state of anxiety is not only patient oneself and is endured to the fullest extent and decoct, and makes especially household's around friend worry greatly, and this is not merely a kind of sub-health state, if treatment not in time, even may be thought of as depression, Mental Subnormality, leads to irremediable loss.But, a kind of sub-health state of the manic conduct of anxiety, and be not suitable for applying antidepressant or non compos mentis medicine, because this does not reach a kind of morbid state, and the strong huge side effect of antipsychotics also makes us forbidding.In sum, at present in Asia, the impatient disease crowd of health state not being had to good solution, therefore people can alleviate in the urgent need to a kind of the medicine appearance that changes impatient state, composition soft of the present invention is as a kind of food of health therapy, the impatient crowd's who not only slows down impatient state, because the material composition of integration of edible and medicinal herbs does not almost have untoward reaction especially, for vast impatient crowd has brought Gospel.
Lavandula angustifolia, as a kind of famous and precious and important natural perfume plant, also has important use aspect medical.As far back as the ancient Rome and Greece epoch, with medicinal and famous.Nowadays, proved that Herba Lysimachiae foenum-graeci quintessence oil has the effects such as sterilization, antifungal, relaxing smooth muscle, tranquilizing soporific.1999, Walsh etc. woke up with a start a research to the nephrotic that asks of long-term inpatients, found that lavandula angustifolia can improve patient's emotion score value, alleviated their painful at heart.1998, the people such as Dieg found that experimenter sucks 10% Herba Lysimachiae foenum-graeci quintessence oil 3 min, will show that health obviously loosens, anxiety score value reduces, mental status is good.2000, the people such as Masego also found that lavandula angustifolia can make electroencephalogram demonstrate the waveform of " feeling comfortable ".
Herba Ocimi (Herba Ocimi Pilosi), as a kind of plant of medicine-food two-purpose, has fragrance powerful and that stimulate, has dispelling wind circulation of qi promoting, and removing dampness helps digestion, effect of blood circulation promoting and blood stasis dispelling, and in addition, Herba Ocimi (Herba Ocimi Pilosi) also has anti-stress effect.People's discoveries such as Archana, noise stress obviously cause total blood cell count minimizing, the rising of plasma corticosterone level and the minimizing of NBT of mice.And it is constant to carry out pretreated Mouse Blood classified counting of leucocyte with Herba Ocimi extract (Herba Ocimi Pilosi extract), thereby explanation Herba Ocimi extract (Herba Ocimi Pilosi extract) has anti-stress effect.The people such as Aravind further study discovery, and sharp-pointed noise can make Free Radical Level in the blood of Cavia porcellus and brain increase, and Herba Ocimi extract (Herba Ocimi Pilosi extract) can reduce Free Radical Level effectively.Therefore, to weaken stress be because it has free radical clean-up effect to Herba Ocimi (Herba Ocimi Pilosi).
Summary of the invention
The invention provides a kind of soft capsule with calm anti-impatient effect and preparation method thereof, object is to pass through CO
2supercritical extraction technique extracts the effective ingredient with the anti-impatient effect of tranquilizing soporific from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), and itself and edible oil are mixed and made into soft capsule.
The technical scheme that the present invention takes is: be to make by the following method:
(a) pre-treatment of lavandula angustifolia: get the lavandula angustifolia medical material after air-dry, lavandula angustifolia is dried, pulverizes, is sieved; The pre-treatment of Herba Ocimi (Herba Ocimi Pilosi): by after air-dry the aerial parts of Herba Ocimi (Herba Ocimi Pilosi) and to its processing that is dried, pulverizes, sieves;
(b) adopt CO
2supercritical extraction method extracts aromatic oil from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), packs 60 ~ 80 parts of 140 ~ 160 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank, taking pressure as 24 ~ 28MPa, temperature is to extract 120 ~ 200 minutes, CO under the condition of 45 DEG C ~ 55 DEG C
2flow is 10 ~ 20L/h;
(c) volatile oil of supercritical extraction and edible oil are mixed and made into soft capsule.
150 parts of lavandula angustifoliaes by weight described in the present invention, 70 parts of Herba Ocimi (Herba Ocimi Pilosi)s.
Edible oil described in the present invention comprises olive oil, Oleum Glycines, salad oil, Oleum Helianthi, Semen Maydis oil, Oleum Arachidis hypogaeae semen, Fructus Perillae oil, Semen Lini oil, in Fructus Hippophae sarcocarp oil one or both or two or more.
Edible oil described in the present invention adopts olive oil.
At present lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi) are at anxiety reduction, manic state, and calm quiet spiritual aspect is effective in cure, but domestic there is not yet passed through CO up to now
2supercritical extraction technique extracts the effective ingredient of calm anti-impatience from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), and is dissolved in the report of making soft capsule in edible oil.
Advantage of the present invention is to pass through CO
2supercritical extraction technique extracts the effective ingredient with calm anti-impatience from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), and itself and edible oil are mixed there is calmness, the soft capsule of anti-impatient effect, for vast impatient disease patient provide effective medicine.
Detailed description of the invention
Embodiment 1
(a) pre-treatment of lavandula angustifolia: get the lavandula angustifolia medical material after air-dry, lavandula angustifolia is dried, pulverizes, is sieved; The pre-treatment of Herba Ocimi (Herba Ocimi Pilosi): by after air-dry the aerial parts of Herba Ocimi (Herba Ocimi Pilosi) and to its processing that is dried, pulverizes, sieves;
(b) adopt CO
2supercritical extraction method extracts aromatic oil from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), packs 60 parts of 140 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank, taking pressure as 24MPa, temperature is to extract 120 minutes, CO under the condition of 45 DEG C
2flow is 10L/h; Extract is buff liquid and a small amount of green paste, and the fragrance of miscella is soft, the approximate true fragrance of a flower, and extraction ratio is 3.26;
(c) volatile oil of supercritical extraction and mixed with olive oil are made to soft capsule.
Embodiment 2
(a) pre-treatment of lavandula angustifolia: get the lavandula angustifolia medical material after air-dry, lavandula angustifolia is dried, pulverizes, is sieved; The pre-treatment of Herba Ocimi (Herba Ocimi Pilosi): by after air-dry the aerial parts of Herba Ocimi (Herba Ocimi Pilosi) and to its processing that is dried, pulverizes, sieves;
(b) adopt CO
2supercritical extraction method extracts aromatic oil from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), packs 70 parts of 150 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank, taking pressure as 26MPa, temperature is to extract 160 minutes, CO under the condition of 50 DEG C
2flow is 15L/h; Extract is buff liquid and a small amount of green paste, and the fragrance of miscella is soft, the approximate true fragrance of a flower, and extraction ratio is 3.54.
(c) volatile oil of supercritical extraction and mixed with olive oil are made to soft capsule.
Embodiment 3
(a) pre-treatment of lavandula angustifolia: get the lavandula angustifolia medical material after air-dry, lavandula angustifolia is dried, pulverizes, is sieved; The pre-treatment of Herba Ocimi (Herba Ocimi Pilosi): by after air-dry the aerial parts of Herba Ocimi (Herba Ocimi Pilosi) and to its processing that is dried, pulverizes, sieves;
(b) adopt CO
2supercritical extraction method extracts aromatic oil from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi), packs 80 parts of 160 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank, taking pressure as 28MPa, temperature is to extract 200 minutes, CO under the condition of 55 DEG C
2flow is 20L/h; Extract is buff liquid and a small amount of green paste, and the fragrance of miscella is soft, the approximate true fragrance of a flower, and extraction ratio is 4.36;
(c) volatile oil of supercritical extraction and mixed with olive oil are made to soft capsule.
In the step (c) of above-described embodiment, by the volatile oil of supercritical extraction and olive oil, Oleum Glycines, salad oil, Oleum Helianthi, Semen Maydis oil, Oleum Arachidis hypogaeae semen, Fructus Perillae oil, Semen Lini oil, or in Fructus Hippophae sarcocarp oil one or both or two or more, be mixed and made into soft capsule.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, obviously, those skilled in the art can carry out various changes and modification and not depart from the spirit and scope of the present invention the present invention.Like this, if these amendments of the present invention and within modification belongs to the scope of the claims in the present invention and equivalent technologies thereof, the present invention is also intended to comprise these changes and modification interior.
Further illustrate the present invention by pharmacodynamic experiment below.
In recent years, Effect of Anti impatience is continued to use the manic scale of Bech-Rafaelsen (BRMS) more, first preliminary experiment animal is carried out to modeling, make its BRMS value reach certain level (generally 11 points of ﹥ are effective), after administration, BRMS value declines proves that effectively decline degree proves that the anti-impatient ability of this medicine is stronger more at most.
The impact of table 1 thing of the present invention on modeling mice BRMS value
Note: with the comparison of blank group, * P ﹤ 0.05, * * P ﹤ 0.01
This experimental result shows: with the comparison of blank group, the big-and-middle dosage group of the present invention and positive drug lithium carbonate all can obviously reduce BRMS value, and small dose group also has certain effect.Point out extract of the present invention to there is obvious anti-impatient effect.
Claims (8)
1. there is a soft capsule for calm anti-impatient effect, it is characterized in that making by the following method:
(a) pre-treatment of lavandula angustifolia: get the lavandula angustifolia medical material after air-dry, lavandula angustifolia is dried, pulverizes, is sieved; The pre-treatment of Herba Ocimi (Herba Ocimi Pilosi): by after air-dry the aerial parts of Herba Ocimi (Herba Ocimi Pilosi) and to its processing that is dried, pulverizes, sieves;
(b) adopt CO
2supercritical extraction method extracts aromatic oil from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi): pack 60 ~ 80 parts of 140 ~ 160 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank, taking pressure as 24 ~ 28MPa, temperature is to extract 120 ~ 200 minutes, CO under the condition of 45 DEG C ~ 55 DEG C
2flow is 10 ~ 20L/h;
(c) volatile oil of supercritical extraction and edible oil are mixed and made into soft capsule.
2. a kind of soft capsule with calm anti-impatient effect according to claim 1, is characterized in that: pack 70 parts of 150 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank.
3. a kind of soft capsule with calm anti-impatient effect according to claim 1 and 2, is characterized in that: described edible oil comprises olive oil Oleum Glycines, salad oil, Oleum Helianthi, Semen Maydis oil, Oleum Arachidis hypogaeae semen, Fructus Perillae oil, Semen Lini oil, in Fructus Hippophae sarcocarp oil one or both or two or more.
4. a kind of soft capsule with calm anti-impatient effect according to claim 3, is characterized in that: described edible oil adopts olive oil.
5. a kind of preparation method of the soft capsule with calm anti-impatient effect as claimed in claim 1, is characterized in that comprising row step:
(a) pre-treatment of lavandula angustifolia: get the lavandula angustifolia medical material after air-dry, lavandula angustifolia is dried, pulverizes, is sieved; The pre-treatment of Herba Ocimi (Herba Ocimi Pilosi): by after air-dry the aerial parts of Herba Ocimi (Herba Ocimi Pilosi) and to its processing that is dried, pulverizes, sieves;
(b) adopt CO
2supercritical extraction method extracts aromatic oil from lavandula angustifolia and Herba Ocimi (Herba Ocimi Pilosi): pack 60 ~ 80 parts of 140 ~ 160 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank, taking pressure as 24 ~ 28MPa, temperature is to extract 120 ~ 200 minutes, CO under the condition of 45 DEG C ~ 55 DEG C
2flow is 10 ~ 20L/h;
(c) volatile oil of supercritical extraction and edible oil are mixed and made into soft capsule.
6. the preparation method of a kind of soft capsule with calm anti-impatient effect according to claim 5, is characterized in that: pack 70 parts of 150 parts of lavandula angustifolia coarse powder, Herba Ocimi (Herba Ocimi Pilosi) coarse powder into CO by weight
2in supercritical extraction tank.
7. according to the preparation method of a kind of soft capsule with calm anti-impatient effect described in claim 5 or 6, it is characterized in that: described edible oil comprises olive oil, Oleum Glycines, salad oil, Oleum Helianthi, Semen Maydis oil, Oleum Arachidis hypogaeae semen, Fructus Perillae oil, Semen Lini oil, in Fructus Hippophae sarcocarp oil one or both or two or more.
8. the preparation method of a kind of soft capsule with calm anti-impatient effect according to claim 7, is characterized in that: described edible oil adopts olive oil.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101305796A (en) * | 2008-07-04 | 2008-11-19 | 昆明七彩云花生物科技有限公司 | Capsule and oral liquid prepared by food plant flower or flower extraction |
| CN102085239A (en) * | 2009-12-07 | 2011-06-08 | 杭州众动教育科技有限公司 | Extracting lavender compositions possessing tranquillizing effect by supercritical CO2 extraction method and application method of lavender compositions |
| CN102965198A (en) * | 2012-11-14 | 2013-03-13 | 陈和平 | Method for extracting and processing lavender essential oil |
-
2014
- 2014-08-26 CN CN201410423782.XA patent/CN104161795A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101305796A (en) * | 2008-07-04 | 2008-11-19 | 昆明七彩云花生物科技有限公司 | Capsule and oral liquid prepared by food plant flower or flower extraction |
| CN102085239A (en) * | 2009-12-07 | 2011-06-08 | 杭州众动教育科技有限公司 | Extracting lavender compositions possessing tranquillizing effect by supercritical CO2 extraction method and application method of lavender compositions |
| CN102965198A (en) * | 2012-11-14 | 2013-03-13 | 陈和平 | Method for extracting and processing lavender essential oil |
Non-Patent Citations (2)
| Title |
|---|
| 关建等: "薰衣草花超临界萃取部位化学成分的研究", 《时珍国医国药》 * |
| 谢慧明等: "超临界CO_2萃取罗勒挥发油的工艺研究", 《食品科学》 * |
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