CN104127340B - Toothpaste and preparation method Dendrobium - Google Patents

Toothpaste and preparation method Dendrobium Download PDF

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CN104127340B
CN104127340B CN201410352689.4A CN201410352689A CN104127340B CN 104127340 B CN104127340 B CN 104127340B CN 201410352689 A CN201410352689 A CN 201410352689A CN 104127340 B CN104127340 B CN 104127340B
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dendrobium
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extract
toothpaste
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俞巧仙
叶智根
俞元省
俞恬伊
王升贵
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浙江森宇实业有限公司
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Abstract

本发明涉及一种铁皮石斛牙膏及其制备方法。 The present invention relates to a method for its preparation Dendrobium toothpaste. 现在还没有一种能够保留铁皮石斛中有效成分的铁皮石斛牙膏及其制备方法。 There is currently no method for its preparation toothpastes Dendrobium Dendrobium active ingredients to be reserved. 本发明的铁皮石斛牙膏包括重量份数为4.0~6.0份的铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质。 Dendrobium toothpastes of the present invention comprises 4.0 to 6.0 parts by weight parts of Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins. 铁皮石斛牙膏的制备方法依次包括如下工序:A前处理工序;B低温超微研磨工序:将水温2~10℃的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6~1:8,启动均质机且控制出料细度在200~300μm以下,得到铁皮石斛提取物母液;C过滤工序;D制膏工序;E灌装工序。 Dendrobium preparing toothpaste comprising the steps of sequentially: A pretreatment step; step B cryogenic attritor: Dendrobium after the water temperature and 2 ~ 10 ℃ disposed cutting homogenizer, and the weight of water Dendrobium ratio of 1: 6 to 1: 8, and controls the start homogenizer fineness of the material at 200 ~ 300μm or less, to obtain Dendrobium extract liquor; filtration step C; D system paste step; E filling step. 本发明以铁皮石斛鲜品为原料进行低温萃取,所得产品中的多糖、维生素、叶绿素、游离氨基酸等含量高。 In the present invention, Dendrobium candidum fresh goods as raw materials for low-temperature extraction, the resulting product is a high content of polysaccharides, vitamins, chlorophyll, free amino acids and the like.

Description

铁皮石斛牙膏及其制备方法 Toothpaste and preparation method Dendrobium

技术领域 FIELD

[0001] 本发明涉及一种牙膏及其制备方法,尤其是涉及一种铁皮石斛牙膏及其制备方法,属于药用植物加工领域。 [0001] The present invention relates to a method for preparing toothpaste and, particularly, to a method for its preparation Dendrobium toothpaste, medicinal plants belonging to the processing field.

背景技术 Background technique

[0002] 1、铁皮石斛简介 [0002] 1, Dendrobium Introduction

[0003] 铁皮石斛为兰科植物铁皮石斛(Dendrobium officinale Kimura et Migo)的新鲜茎,属于国家保护植物,具有珍贵的养生与药用价值。 [0003] Dendrobium orchid plants of Dendrobium (Dendrobium officinale Kimura et Migo) Fresh stem, a state protected plants, and having medicinal value precious health. 铁皮石斛因其表皮呈铁绿色而得名,历代中药典籍均有记载,综合《神农本草经》、《本草纲目》、《纲目拾遗》、《别录》等经典著作对铁皮石斛的论述,其主要功效为强阴益精,清热生津,可补五脏虚劳,厚肠胃,强健筋骨,安神定惊,轻身延年。 Dendrobium its iron skin was green, named after ancient Chinese medicine books have documented, comprehensive "Shen Nong's Materia Medica", "Compendium of Materia Medica", "Checklist Supplements", "Do not record" and other classics discussion of the Dendrobium, which The main effect is a strong female essence, heat fluid, can make up the five internal organs Consumption, thick stomach, strong bones, sedative given shock, Qingshenjianfei sickness. 道家养生经典著作《道藏》将铁皮石斛、天山雪莲、三两重的人参、 百二十年的首乌、花甲之茯苁(茯苓和苁蓉)、深山灵芝、海底珍珠、冬虫夏草并称为中华九大仙草,铁皮石斛名列首位。 Taoist classic "Taoist" The Dendrobium, the Tianshan snow lotus, the three double ginseng, Radix hundred and ten years, the sixtieth Fu Boschniakia glabra (Poria and BREE), Ganoderma mountains, submarine pearls, Chinese caterpillar fungus and called nine immortality, Dendrobium ranked first.

[0004] 铁皮石斛性味:甘,微寒,入胃、肾经。 [0004] Dendrobium taste: sweet, slightly cold, stomach, kidney. 性属清润,清中有补,补中有清。 Sex is moist, there are clear up, fill in the Qing.

[0005] 铁皮石斛的功效作用,历代名医各有论述: [0005] Efficacy of Dendrobium, medical history each discussed:

[0006] 《本草通玄》云:"石斛,甘能悦脾,咸能益肾,故多功于水土二脏:但气性宽缓,无捷奏之功,古人以此代茶,甚清膈上。" [0006] "Herbal Tongxuan" says: "Dendrobium, Hyatt Gan can spleen, kidney salty, so much power in the two dirty water and soil: gas-relief but no Czech Republic played power, this ancient tea, even clear the diaphragm. "

[0007] 《本草纲目拾遗》云:"石斛清胃除虚热、生津已劳损,以之代茶,功同参芪。" [0007] "Compendium of Materia Medica" says: "In addition to Hot Dendrobium Qingwei, fluid has been strained to the tea, work with Shenqi."

[0008] 《药性》中载石斛"夏日代茶,生津润喉,强阴健足力。"可见,石斛作为祛病健身的高级滋补品由来已久。 [0008] "medicinal" contains Dendrobium "Summer of tea, Sheng Jin throat, Yin Jian strong enough force." Visible, Dendrobium as a senior tonic healing and fitness for a long time. 中医认为,石斛在萎缩性胃炎、肿瘤、糖尿病、咽喉炎以及白内障等疾病治疗中都可以广泛应用。 Chinese medicine, Dendrobium in the treatment of atrophic gastritis, cancer, diabetes, cataracts and other diseases of the throat and can be widely used. 铁皮石斛有多种药理作用,如增强机体的免疫能力,抗氧化、抗衰老,降低血糖,养阴生津等等。 Dendrobium has a variety of pharmacological effects, such as enhancing the immune capacity, anti-oxidation, anti-aging, lowering blood glucose, YangYinShengJin like. 中医认为,"阴平阳秘,精神乃治。"如阴津亏虚,不能涵阳, 阳浮无制,阴阳平衡遭到破坏,则诸病丛生。 Chinese medicine, "Yin Pingyang secret, the spirit of governance." As Yin-chun deficiency, can not Han Yang, Yang made no floating, yin and yang balance is destroyed, the various diseases have arisen. " "

[0009] 《灵枢•本神篇》曰:"五脏主藏精者也,不可伤,伤则失守而阴虚,阴虚则无气,无气则死矣。"铁皮石斛正是滋阴生津要药,人间故称之"救命仙草"。 [0009] "God Lingshu • The chapter," said: "the five internal organs were also stores the essence, not hurt, the fell and hurt Yin, Yin no gas, no gas then is dead." It Dendrobium Yin Jin Yao raw medicine, human hence the term "help immortality."

[0010]《神农本草经》:主伤中、除痹、下气、补五脏虚劳羸瘦、强阴、久服厚肠胃。 [0010] "Shen Nong": main injury, in addition to Bi, under gas, consumptive Leishou five internal organs, strong female, Jiufu thick stomach.

[0011] 《本草纲目》:强阴益精。 [0011] "Compendium of Materia Medica": strong female essence. 久服,厚肠胃,补内绝不足,平胃气,长肌肉,逐口腔邪热痱气,脚膝疼冷痹弱,定智除惊,轻身延年。 Jiufu, thick stomach, absolutely insufficient within the fill, flat Wei Qi, long muscles, by oral evil prickly heat air, cold feet knee pain paralysis weak, given wisdom in addition to shock, light-weight sickness.

[0012] 《纲目拾遗》:清胃除虚热,生津已劳损,以之代茶,开胃健脾。 [0012] "Checklist Supplements": In addition to Hot Qingwei, fluid has been strained to the tea, appetizers and spleen. 定惊疗风,能镇涎痰, 甘芳降气。 Frightened air treatment, sputum saliva can town, Gan aryl lower gas.

[0013]《药品化义》:治肺气久虚,咳嗽不止。 [0013] "Drugs of justice": cure lung long illness, coughing.

[0014] 《别录》:益精补内绝不足,平胃气,长肌肉,逐口腔邪热气,脚膝疼软弱,健阳,补肾积精。 [0014] "Do not record": within Yijing absolutely insufficient, Ping Wei Qi, long muscles, evil heat by mouth, feet sore knees weak, Yang Jian, kidney fine product.

[0015] 《日华子本草》:治虚损劣弱壮筋骨,暖水脏,益智,平胃气,逐虚邪。 [0015] "Japan Hanako Materia Medica": bad government wasting weak bones and muscles strong, warm water dirty, puzzle, Ping Wei Qi, by imaginary evil.

[0016] 《本草再新》:理胃气,清胃火。 [0016] "Materia Medica and then new": Li Wei Qi, Qing Wei Huo. 除心中烦渴,疗肾经虚热,安神定惊,解盗汗,能散暑。 In addition to the hearts of thirst, cure kidney Hot, sedative given shock, night sweats solution, energy spread summer.

[0017] 2、铁皮石斛用于口腔的功效 [0017] 2, the efficacy of the oral cavity for Dendrobium

[0018]现代科学研究表明,铁皮石斛富含多糖、石斛碱、游离氨基酸、维生素(维生素A、维生素C、维生素E)、叶绿素以及各种酶,不仅可以通过口服吸收,铁皮石斛还能止血、促进伤口愈合,可外用于修复受损口腔。 [0018] Modern scientific research shows, rich in polysaccharides of Dendrobium, Dendrobium base, free amino acids, vitamins (vitamin A, vitamin C, vitamin E), chlorophyll and various enzymes, not only by oral absorption, Dendrobium can stop bleeding, promote wound healing, it can be used to repair damaged outer mouth.

[0019]试验证明,铁皮石斛可使口腔溃疡病损部位得到机械保护,增强局部口腔黏膜的抗炎和修复能力,使溃疡愈合加快。 [0019] Tests show that Dendrobium oral ulcer lesion site can give mechanical protection, enhanced topical oral anti-inflammatory and repair capacity, so that ulcer healing accelerated. 将新鲜铁皮石斛嚼烂后敷于溃疡面,能显著加快溃疡愈合,久服能预防腔溃疡的发生,有效率达90%以上。 After fresh Dendrobium chewed spreads ulcers, can significantly accelerate the healing of ulcers, ulcers Jiufu can prevent the occurrence of cavities, the effective rate of 90%. 《医醇剩义》等铁皮石斛方《葛根白虎汤》、《清热胃关煎》均具有治疗牙痛功效。 "Medical alcohol remaining sense" Dendrobium other side "Gegen BHT", "heat off stomach fried" toothache have therapeutic efficacy. 通过对服用森山铁皮石斛的顾客调查表明,铁皮石斛对牙周炎、口腔溃疡、牙龈出血均有良好的效果。 By taking the customer survey showed Moriyama Dendrobium, Dendrobium periodontitis, oral ulcers, bleeding gums have good results.

[0020] 铁皮石斛多糖具有抗菌、消炎、增强细胞免疫活性的功能,用于口腔可抑制细菌繁殖,有效防止口腔异味;铁皮石斛多糖外用可以止血,并能促进纤维蛋白的生长,从而促进伤口愈合,修复受损口腔组织。 [0020] Dendrobium polysaccharide having anti-bacterial, anti-inflammatory, immune enhancement activity in a cell, to inhibit oral bacteria, effectively preventing mouth odor; Dendrobium polysaccharide can topical hemostasis, and promote the growth of fibrin, thereby promoting wound healing repair damaged oral tissue. 铁皮石斛含有氨基酸和对人体有益的多种微量元素,且内含的水溶性多糖为一类免疫增强剂,可提高白细胞,促进淋巴细胞产生淋巴因子,从而增强机体体液免疫功能、细胞免疫功能,增强机体自身免疫,促进恢复。 Dendrobium comprising amino acids and trace elements beneficial to human body, and the water-soluble polysaccharide containing a class of immunopotentiators can increase white blood cells, lymphocytes promoting lymphokines, thereby enhancing the function of humoral immunity, cellular immunity, enhance the body's own immunity, promote recovery. 中医理论认为,铁皮石斛性微寒,是滋阴圣品,而口疮、溃疡、牙龈肿痛等多为阴虚火旺所致,故铁皮石斛可用于上述口腔问题。 Chinese medicine theory, Dendrobium slightly cold, Yin is the saint, and mouth sores, ulcers, and other gingival swelling due to wang, it may be used in the above Dendrobium oral problems.

[0021] 传统的煎煮提取方法会致铁皮石斛中维生素、氨基酸、活性酶等成分的破坏。 [0021] The traditional method of boiling extraction will be induced in Dendrobium vitamins, amino acids, enzymes destroying the active ingredient. 公开日为2013年08月07日,公开号为CN103230356A的中国专利申请中,公开了一种金钗石斛牙膏,该金钗石斛牙膏的组份为(按重量比):牙膏膏体70份、金钗石斛提取物20份和鱼腥草提取物10份,其中,金钗石斛提取物的制备如下:取金钗石斛榨汁后放入提取罐,于80°C温度下浸提45分钟,趁热过滤,将滤液用减压蒸馏的方法于35-45°C温度条件下浓缩至1/10体积,将浓缩液冷却至8°C过滤,取滤液作为金钗石斛浓溶液备用;如果将该专利申请文件中金钗石斛提取物的制备方法应用于铁皮石斛的提取中,将会破坏铁皮石斛中维生素、氨基酸、活性酶等成分。 Publication date is August 7, 2013, Chinese Patent Publication No. CN103230356A, there is disclosed a Dendrobium nobile toothpaste, part of the Dendrobium nobile toothpaste group (ratio by weight): 70 parts toothpaste paste, Dendrobium nobile extract Houttuynia cordata extract and 20 parts 10 parts, wherein, Dendrobium nobile extract prepared as follows: extraction tank after taking into Dendrobium nobile juice extraction at a temperature of 80 ° C for 45 minutes. filtered while hot, and the filtrate was concentrated by distillation under reduced pressure to a volume of 1/10 at a temperature of 35-45 ° C, the concentrated solution was cooled to 8 ° C by filtration, the filtrate was concentrated Dendrobium nobile as standby; if the patent application document Dendrobium nobile extract preparation was applied in Dendrobium extract, Dendrobium destroys vitamins, amino acids, enzymes active ingredient. 现在还没有一种能够保留铁皮石斛中有效成分的铁皮石斛牙膏及其制备方法。 There is currently no method for its preparation toothpastes Dendrobium Dendrobium active ingredients to be reserved.

发明内容 SUMMARY

[0022] 本发明的目的在于克服现有技术中存在的上述不足,而提供一种尽可能的保留铁皮石斛有效成分,拓展铁皮石斛应用领域,充分发挥铁皮石斛价值的铁皮石斛牙膏及其制备方法。 [0022] The object of the present invention is to overcome the above disadvantages present in the prior art, and to provide an active ingredient as retention of Dendrobium, Dendrobium expand the application field, toothpastes and full preparation Dendrobium Dendrobium Value . 该铁皮石斛牙膏及其制备方法以铁皮石斛鲜品为原料进行低温萃取,省去传统铁皮楓斗的烘干工序,有效分成不易被破坏,所得产品中的多糖、维生素、叶绿素、游离氨基酸等含量高。 The Dendrobium toothpaste and preparation method Dendrobium fresh products as raw material for low-temperature extraction, eliminating the traditional drying step Dendrobium, effectively divided into easily damaged, the polysaccharide content of the resulting product, vitamins, chlorophyll, free amino acids high.

[0023] 本发明解决上述问题所采用的技术方案是:该铁皮石斛牙膏的特点在于:该铁皮石斛牙膏包括重量份数为40.0~50.0份的山梨糖醇;重量份数为10.0~20.0份的水;重量份数为18.0~22.0份的水合硅石;重量份数为8.0~12.0份的甘油;重量份数为4.0~6.0份的铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质;重量份数为3.0~5.0份的聚乙二醇400;重量份数为1.0~2.0份的月桂醇硫酸酯钠;重量份数为0.6~ 〇. 8份的羧甲基纤维素钠;重量份数为0.8~1.2份的食用香精;重量份数为0.1~0.2份的皱波角叉菜;重量份数为〇. 1~〇. 3份的黄原胶;重量份数为0.1~0.3份的糖精钠;重量份数为0.3~0.5份的黄芩提取物;重量份数为0.3~0.5份的三七提取物;重量份数为0.1~0.2份的丹皮酚;重量份数为〇. 03~0.05份的云母粉;重量份数为0.02~0.04份的CI19140;重量份数为0.02~0.04份的CI42090。 [0023] aspect of the present invention to solve the above problem is that: the Dendrobium toothpaste characterized in that: the Dendrobium dentifrice comprising 40.0 to 50.0 parts by weight parts of sorbitol; 10.0 to 20.0 parts by weight of parts water; 18.0 parts by weight to 22.0 parts of hydrated silica; 8.0 to 12.0 parts by weight parts of glycerol; 4.0 to 6.0 parts by weight of parts of Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins; parts by weight of 3.0 to 5.0 parts polyethylene glycol 400; 1.0 parts by weight to 2.0 parts of sodium lauryl alcohol sulfate ester; billion parts by weight of 0.6 to 8 parts of carboxymethyl cellulose. sodium; 0.8 to 1.2 parts by weight parts of food flavor; 0.1 parts by weight to 0.2 parts by corrugated wave carrageenan; billion parts by weight of 1 to 3 billion parts of xanthan gum;. parts by weight of 0.1 to 0.3 parts of sodium saccharin; 0.3 parts by weight to 0.5 parts of Scutellaria root extract; 0.3 parts by weight to 0.5 parts by notoginseng extract; 0.1 parts by weight to 0.2 parts by paeonol; parts by weight number 03 billion to 0.05 parts mica;. 0.02 to 0.04 parts by weight parts of CI 19140; parts by weight of 0.02 to 0.04 parts of CI 42090. 由此使得本发明中铁皮石斛牙膏的配方科学、合理,成分之间会产生协同作用,能够更加有效的发挥出铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质的功效,且更加有利于皮肤吸收铁皮石斛提取物中含有的多糖、叶绿素、维生素和蛋白质。 Thereby enabling the present invention Dendrobium toothpaste formulation science, rational, synergistically between components, can more effectively exert the effect Dendrobium extract contains polysaccharides, chlorophyll, vitamins and proteins, and more beneficial to the skin absorbent polysaccharide extracted from Dendrobium, chlorophyll, vitamins and proteins contained in the composition.

[0024] 作为优选,本发明所述铁皮石斛提取物采用如下方法制得:将洗净后的新鲜的铁皮石斛置于沸水中消毒3~5min,取出后置于水中冷却,然后进行切断,将水温2~10°C的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6~1:8,启动均质机且控制出料细度在200~300wii以下,得到铁皮石斛提取物母液,对铁皮石斛提取物母液进行过滤得到铁皮石斛提取物。 [0024] Advantageously, the present invention Dendrobium extract prepared as follows: fresh Dendrobium placed in boiling water after washing disinfection 3 ~ 5min, cooling water taken out was placed, and then cut the water 2 ~ 10 ° C and water was placed after cutting homogenizer Dendrobium, Dendrobium to water weight ratio of 1: 6 to 1: 8, and controls the start homogenizer fineness of 200 to 300wii hereinafter, Dendrobium extract obtained mother liquor, the mother liquor Dendrobium extract obtained was filtered Dendrobium extract.

[0025] -种铁皮石斛牙膏的制备方法,其特点在于:依次包括如下工序: [0025] - The method of producing Dendrobium toothpaste, characterized in that: comprising the steps of sequentially:

[0026] A前处理工序, [0026] A pretreatment step,

[0027] a铁皮石斛原料要求, [0027] a Dendrobium raw material requirements,

[0028]在开花之前采收铁皮石斛; [0028] Dendrobium harvest before flowering;

[0029] b 杀菌, [0029] b sterilization,

[0030]洗净后的新鲜的铁皮石斛置于沸水中消毒3~5min,取出后置于水中冷却; [0030] Fresh Dendrobium placed in boiling water after washing disinfection 3 ~ 5min, cooling water taken out is placed;

[0031] c 切段, [0031] c cut into sections,

[0032]将铁皮石斛切段; [0032] The Dendrobium cut into sections;

[0033] B低温超微研磨工序, [0033] B Attritor cryogenic step,

[0034] 将水温2~10°C的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6~1:8,启动均质机且控制出料细度在200~300M1以下,得到铁皮石斛提取物母液; [0034] The temperature of 2 ~ 10 ° C and water was placed after cutting homogenizer Dendrobium, Dendrobium weight ratio to water is 1: 6 to 1: 8, and controls the starting material homogenizer fine 200 ~ 300M1 degree or less, Dendrobium extract to give a mother liquor;

[0035] C过滤工序, [0035] C filtration step,

[0036] 对铁皮石斛提取物母液进行过滤得到铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质; [0036] Dendrobium extract obtained was filtered mother liquors Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins;

[0037] D制膏工序, [0037] D step paste system,

[0038]先将配方量的铁皮石斛提取物、黄芩提取物、三七提取物、丹皮酚、山梨糖醇、甘油、聚乙二醇400、皱波角叉菜、月桂醇硫酸酯钠、羧甲基纤维素钠、黄原胶和糖精钠用配方量的水溶解,加入到制膏锅中,再将配方量的水合硅石、云母粉、CI19140和CI42090加入到制膏锅中;添加完毕后,再添加配方量的食用香精,进行刮板搅拌、均质搅拌和研磨,得膏体;打出少量的膏体进行检验,合格后,再打入膏体储存锅进行陈化,使物料自然冷却至常温,同时使物料充分膨胀形成均相的粘合体,提高物料的弹性,从而得铁皮石斛牙膏; [0038] Formulation amount of the first Dendrobium extract, Scutellaria root extract, Panax extract, Paeonol, sorbitol, glycerin, polyethylene glycol 400, wrinkled wave carrageenan, sodium lauryl alcohol sulfate ester, sodium carboxymethyl cellulose, xanthan gum and sodium saccharin water with the formulation amount of dissolved, was added to the paste pot system, then the formula amount of hydrated silica, mica, CI 19140, and added to the prepared paste pot CI42090; the addition was complete after, add formula amount of food flavors, a scraper stirring, homogeneous mixing and grinding, to obtain paste; play a small amount of paste tested, qualified, and then paste into the storage pan subjected to aging, the natural materials cooled to room temperature, while the expanded material sufficient to form a homogeneous bonded body, increase the flexibility of the material, thereby obtaining a toothpaste Dendrobium;

[0039] E灌装工序, [0039] E filling step,

[0040]将铁皮石斛牙膏进行灌装。 [0040] The filling toothpaste Dendrobium.

[0041]由此使得本发明整个铁皮石斛提取物的加工过程,除瞬间灭菌之外,都在45°C以下完成,充分保留了铁皮石斛中的各种有效成分。 [0041] thereby making the entire process Dendrobium extract of the present invention, in addition to the flash pasteurization, were completed at 45 ° C or less, sufficient to retain the various active ingredients in Dendrobium.

[0042]作为优选,本发明所述A前处理工序的a铁皮石斛原料要求中,铁皮石斛原料为三年生长期的铁皮石斛。 [0042] Advantageously, the raw material requirements Dendrobium A A pretreatment step of the present invention, the raw material for the three growth Dendrobium Dendrobium.

[0043]作为优选,本发明所述A前处理工序的b杀菌中,在200L敞口锅中加入150L纯化水, 加热煮沸,铁皮石斛先用自来水冲洗3遍,再用纯化水冲洗2遍,用不锈钢夹将铁皮石斛置沸水中"淬" 3~5min,取出后置纯化水中冷却。 [0043] Advantageously, b A sterilizing the pretreatment step of the present invention, the open pot 200L 150L of purified water was added, heated to boiling, Dendrobium rinse 3 times with tap water, purified water, then rinsed 2 times, the Dendrobium in boiling water "quenching" 3 ~ 5min, then cool the rear of purified water with a stainless steel clip.

[0044] 作为优选,本发明所述C过滤工序依次包括如下步骤: [0044] Advantageously, the filtration step C of the present invention comprises the following steps in sequence:

[0045] a粗滤步骤, [0045] a straining step,

[0046] 将100目尼龙滤布浸湿,折叠成2层平铺于真空抽滤的漏斗内,边缘置于漏斗之外, 开启真空抽滤机,真空度大于〇. 〇7MPa,再将铁皮石斛提取物母液倒入漏斗内,过滤得到的粗滤液,当滤渣厚度达到0.5~lcm时清理一次; [0046] A 100-mesh nylon cloth soaked in folded into the inner plated layer 2 by vacuum filtration funnel, the funnel was placed outside the edge, turn vacuum filtration, vacuum is greater than square. 〇7MPa, then iron Dendrobium extract liquor is poured into the funnel, the filtrate was filtered to give the crude, when cleaning a filter cake thickness of 0.5 ~ lcm;

[0047] b精滤步骤, [0047] b fine filtration step,

[0048]启动高速管式离心机和蠕动栗,高速管式离心机的转速为15000r/min,蠕动栗的转速为150~250r/min,将进料管至粗滤液内,离心过滤后得到铁皮石斛提取物,将铁皮石斛提取物置于药液储存罐内,每离心过滤200~300L清理滤渣一次。 [0048] Start-speed tubular centrifuge and peristaltic Li, high speed centrifuge tube speed of 15000r / min, the speed of the peristaltic Li 150 ~ 250r / min, the crude feed tube into the filtrate obtained after centrifugation metal Dendrobium extract, Dendrobium extract was placed in the liquid storage tank, a centrifugal filter 200 ~ 300L per cake cleanup time.

[0049] 作为优选,本发明所述D制膏工序中,陈化时间为120分钟。 [0049] Advantageously, the step D paste prepared in the present invention, the aging time is 120 minutes.

[0050] 作为优选,本发明所述D制膏工序中,在进行刮板搅拌、均质搅拌和研磨时,采用夹套冷却水控制温度在45 °C以下。 [0050] Advantageously, the step D paste prepared in the present invention, when the stirring blade, and grinding the homogeneous stirring is performed using cooling water jacket temperature was controlled at 45 ° C or less.

[0051] 作为优选,本发明所述E灌装工序,在自动灌装线上完成,装灌过程中调节好装灌量、封尾温度和机器速度,定时检查牙膏重量和封尾质量。 [0051] Advantageously, the present invention is the filling step E, to complete the automatic filling line, during the bottling regulate filled amount, temperature and sealing machine speed, by weight of the toothpaste and regularly check the quality of sealing.

[0052] 一种铁皮石斛牙膏,其特点在于:该铁皮石斛牙膏采用如上制备方法制备而成。 [0052] A toothpaste Dendrobium, characterized in that: the toothpaste prepared from Dendrobium prepared as above using the method. [0053]本发明与现有技术相比,具有以下优点和效果:本品以铁皮石斛鲜品为原料进行低温萃取,省去传统铁皮楓斗的烘干工序,尽可能的保留铁皮石斛有效成分,有效成分不易被破坏,所得产品中多糖、维生素、叶绿素、游离氨基酸等含量高,因此本发明较之传统工艺有明显的优势。 [0053] Compared with the prior art the present invention has the following advantages and effects: This product is fresh goods Dendrobium low temperature extraction of raw materials, eliminating the traditional drying step Dendrobium, Dendrobium active ingredient to retain as much as possible , the active ingredient is not easily destroyed, the resulting products of high content of polysaccharides, vitamins, chlorophyll, free amino acids, thus the present invention over conventional processes have a distinct advantage.

[0054] 本发明以铁皮石斛鲜品为原料进行低温萃取,将铁皮石斛中的多糖、石斛碱、氨基酸最大程度的萃取出来,同时保护铁皮石斛中的叶绿素、维生素以及活性酶等成分免受高温破坏。 [0054] In the present invention, Dendrobium fresh products as raw material for low-temperature extraction, the extracted maximum out of polysaccharides of Dendrobium, Dendrobium bases, amino acids, while protecting the Dendrobium chlorophyll, vitamins and enzymes active ingredient from heat damage. 整个铁皮石斛提取物的加工过程,除瞬间灭菌之外,都在30°C以下完成,即便是在铁皮石斛牙膏的加工过程,其温度也控制在45°C以下,充分保留了铁皮石斛中的各种有效成分,省去传统铁皮楓斗的烘干工序,有效成分不易被破坏。 Entire process Dendrobium extract, in addition to the flash pasteurization, are below 30 ° C to complete, even in the process of Dendrobium toothpaste, which is also controlled at a temperature of 45 ° C or less, sufficient to retain the Dendrobium candidum the various active ingredients, eliminating the traditional drying step Dendrobium, the active ingredient is not readily broken. 实验证明,采用本发明中铁皮石斛牙膏的制备方法所得到的铁皮石斛提取物中,按照铁皮石斛提取物折干后计算,多糖含量达到60% (是传统煎煮提取工艺的1.5~2倍),维生素C含量达到50mg/100g(是传统煎煮提取工艺的20倍),叶绿素含量达到60mg/100g(传统煎煮提取工艺几乎使叶绿素成分全部被破坏),蛋白质含量也可达到8.9% (约为传统煎煮提取工艺的1.2~1.5倍),且萃取得率也较之传统工艺高出1.5倍以上,因此本发明所采用的萃取工艺优势明显。 Experiments show that the method of the present invention is prepared in the toothpaste Dendrobium Dendrobium extract obtained in accordance with the calculated after a dry Dendrobium extract, a polysaccharide content of 60% (boiling extraction process is a conventional 1.5 to 2 times) vitamin C content of 50mg / 100g (boiling extraction process is a conventional 20-fold), the chlorophyll content of 60mg / 100g (traditional decoction process of extracting chlorophyll component almost completely destroyed), protein content up to 8.9% (from about conventional boiling extraction process is 1.2 to 1.5 times), and the extract yield is also higher than 1.5 times or more conventional processes, the process is therefore evident advantages of the present invention is employed in the extraction.

[0055] 本发明使得铁皮石斛中的多糖、叶绿素、维生素和蛋白质等成分可通过口腔吸收, 可为口腔提供非常丰富的营养,有文献报道,铁皮石斛有止血和促进伤口愈合的功效,外用可修复受损口腔,本发明开拓了铁皮石斛的应用领域,具有非常广阔的市场前景。 [0055] The present invention makes Dendrobium polysaccharides, chlorophyll, vitamins and proteins and other components may be through the oral absorption, provides a very rich nutrition for oral, it has been reported, Dendrobium hemostasis and promote wound healing effect, external use repair damaged mouth, open up the application field of the invention Dendrobium, and has a very broad market prospects. 由于目前铁皮石斛产品多以内服为主,本发明拓展了铁皮石斛的应用领域,更为充分地发挥铁皮石斛的价值。 Due to the current Dendrobium products and more or less based services, to expand the application field of the invention Dendrobium, more fully maximize the value of Dendrobium.

附图说明 BRIEF DESCRIPTION

[0056] 图1是本发明实施例中铁皮石斛牙膏的制备方法的流程示意图。 [0056] FIG. 1 is a flow chart of the method for preparing toothpaste Dendrobium embodiment of the present invention.

[0057] 图2是本发明实施例中铁皮石斛提取物制备工艺的流程示意图。 [0057] FIG. 2 is a schematic flow diagram of the preparation process of Example Dendrobium extract embodiment of the present invention.

具体实施方式 Detailed ways

[0058] 下面结合附图并通过实施例对本发明作进一步的详细说明,以下实施例是对本发明的解释而本发明并不局限于以下实施例。 [0058] The following Examples and accompanying drawings further illustrate the present invention in detail, the following Examples are intended to explain the present invention and the present invention is not limited to the following embodiments.

[0059] 实施例。 [0059] Example.

[0060] 参见图1至图2, [0060] Referring to FIGS. 2,

[0061]表一铁皮石斛萃取工艺及主要参数[0062] [0061] Table Dendrobium extraction process and the main parameters [0062]

Figure CN104127340BD00081

[0063]再是铁皮石斛提取物与其他组分的配比,具体详见表二。 [0063] Dendrobium extract is then the ratio of other components, in particular Table II.

[0064]表二铁皮石斛牙膏配方「00651 [0064] Table II Dendrobium toothpaste formulations "00651

Figure CN104127340BD00082

[0067] 最后确定铁皮石斛牙膏的制备工艺及参数。 [0067] Preparation and finalizing parameters Dendrobium toothpaste.

[0068] 本实施例中铁皮石斛牙膏的制备方法依次包括如下工序: [0068] In the present embodiment, Dendrobium toothpaste preparation comprising the steps of sequentially:

[0069](一)前处理 [0069] (a) Pretreatment

[0070] 1、铁皮石斛原料要求 [0070] 1, raw material requirements Dendrobium

[0071]选择三年生长期的铁皮石斛,并在开花之前(4月~6月)时采收。 [0071] harvest (4 months to 6 months) before selecting three flowering growth Dendrobium, and. 经实验证明,花期之前是铁皮石斛生长最旺盛的时期,铁皮石斛多糖、维生素、游离氨基酸、叶绿素及其他活性酶含量是全年中最高的,且其表皮和茎都呈铁绿色,纤维含量低,利于提高产品萃取得率。 The experiment proved that, before the flowering period is the most vigorous growth of Dendrobium, Dendrobium polysaccharides, vitamins, free amino acids, chlorophyll and other active enzyme content of the year is the highest, and stems and which radiate low-skin iron green fiber content , which will help improve product extraction yield.

[0072] 2、杀菌 [0072] 2, sterilization

[0073]在200L敞口锅中加入150L纯化水,加热煮沸,将铁皮石斛用自来水冲洗3遍,再用纯化水冲洗2遍,用不锈钢夹取适量铁皮石斛置沸水"淬" 3~5min,取出置纯化水中冷却。 [0073] In an open pot 200L 150L of purified water was added, heated to boiling, the Dendrobium washed three times with tap water, then rinsed 2 times purified water, appropriate amount of stainless steel clip Dendrobium boiling water "quenching" 3 ~ 5min, remove postpurifier cooling water.

[0074] 3、切段 [0074] 3, cut into sections

[0075] 取杀菌完毕的铁皮石斛,以切药机进行切段,切速控制是150~180次/min,每段长度控制在0.5~1.5cm,切好的铁皮石斛段用消毒过的不锈钢桶收集,备用。 [0075] completed sterilization Dendrobium taken to cut drug machine and cut into sections, shear speed control 150 to 180 times / min, each length control 0.5 ~ 1.5cm, Dendrobium cut segments with sterile stainless steel bins to collect and set aside.

[0076](二)低温超微研磨工艺及参数 [0076] (ii) a low temperature and process parameters attritor

[0077]首先将均质机各个部件进行清洗,并用体积百分比为75%的乙醇消毒,待乙醇挥干,安装设备,调整定子与转子的间隙,使之在0.3~0.5mm,开启冷却水阀门。 [0077] First, the various components for cleaning homogenizer, and the volume percentage is 75% ethanol disinfection, alcohol to be evaporated to dryness, installation of equipment, adjusting the gap of stator and rotor, so that in the 0.3 ~ 0.5mm, the cooling water valve is turned on . 取适量低温纯化水(水温2~10°C),称重,倒入均质机料斗中,使纯化水液面在料斗的1/3~2/3之间。 Purified water proper amount of low temperature (temperature of 2 ~ 10 ° C), was weighed, poured into a homogenizer hopper, so that between the hopper 1/3 to 2/3 purified water level. 再取适量上述切好段的铁皮石斛,称重,使铁皮石斛与纯化水的比例为1:6~1:8。 And then take the ratio of the above amount Dendrobium chopped segments, weighing the Dendrobium purified water is 1: 6 to 1: 8. 将出料阀门调至"循环",启动均质按钮,监测出料细度,使粒径控制在200~300wii以下,铁皮石斛超微研磨液用中转桶收集,备用。 The discharge valve is adjusted to "cycle" button to start the homogenization, the fineness monitoring, controlling a particle diameter less 200 ~ 300wii, Dendrobium attritor was collecting tub with relay standby.

[0078](三)过滤工艺及参数 [0078] (c) the filtration process and parameters

[0079] 1、粗滤 [0079] 1, straining

[0080] 将100目尼龙滤布浸湿,折叠成2层平铺于真空抽滤的漏斗内,边缘置于漏斗之外, 开启真空抽滤机,确保真空度大于0. 〇7MPa,再将铁皮石斛超微研磨液倒入漏斗内,过滤至药液储存罐内,滤渣厚度达到0.5~lcm时清理一次,收集滤渣另作他用。 [0080] A 100-mesh nylon cloth soaked in folded into the inner plated layer 2 by vacuum filtration funnel, the funnel edge disposed outside the vacuum suction machine is turned on, to ensure a degree of vacuum greater than 0.03 〇7MPa, then when a cleaning liquid into the attritor Dendrobium funnel, liquid storage tank to the filter, the filter cake thickness of 0.5 ~ lcm, residue collected for other purposes.

[0081] 2、精滤 [0081] 2, fine filter

[0082] 启动高速管式离心机(15000r/min)和蠕动栗,设定蠕动栗的转速为150~250r/ min,将进料管至粗滤液内,离心过滤后得到铁皮石斛提取物,将该铁皮石斛提取物置于药液储存罐内,每离心过滤200~300L清理滤渣一次,过滤收集的滤渣,与粗滤中得到的滤渣合并,另作他用。 [0082] Start-speed tubular centrifuge (15000r / min) and peristaltic chestnut, chestnut creep speed is set to 150 ~ 250r / min, the crude feed tube into the filtrate obtained after centrifugation Dendrobium extract, the the extract is dried Dendrobium liquid storage tank, a centrifugal filter 200 ~ 300L per cake cleanup once collected by filtration residue, the resulting crude residue was filtered combined, for other purposes.

[0083](四)牙膏的制备工艺及参数 [0083] (iv) Preparation and parameters toothpaste

[0084]根据工艺配方,先将铁皮石斛提取物、黄芩提取物、三七提取物、丹皮酚、山梨糖醇、保湿剂(甘油、聚乙二醇400、皱波角叉菜)、发泡剂(月桂醇硫酸酯钠)、稳定剂(羧甲基纤维素钠、黄原胶)、甜味剂(糖精钠)在预溶锅或预混锅中用配方量的水溶解至均匀,加入到制膏锅中,再将摩擦剂(水合硅石、云母粉)、着色剂(Cl 19140、CI42090)加入到制膏锅中;添加完毕后,再添加香料(食用香精),进行刮板搅拌、均质搅拌、研磨。 [0084] According to the process recipe, first Dendrobium extract, Scutellaria root extract, Panax extract, Paeonol, sorbitol, humectants (glycerin, polyethylene glycol 400, wrinkled carrageenan wave), hair foaming agent (sodium lauryl alcohol sulfate ester), stabilizers (sodium carboxymethyl cellulose, xanthan gum), sweeteners (saccharin sodium) pre-dissolved in the premix pot or pan with water to a uniform dissolution of the formulation amount, was added to the paste pot system, then the friction agent (hydrated silica, mica), a colorant (Cl 19140, CI42090) was added to a cream pot made; after the addition is complete, add flavor (food flavors), a stirring blade , homogeneous stirring, milling.

[0085]因在捏合、研磨过程中,膏料中会产生气泡,故需同时进行抽真空,直至真空度达-0.096MPa为止,时间约为50分钟。 [0085] by kneading, grinding, the paste bubbles are generated, so the need simultaneously evacuated until the degree of vacuum reached -0.096MPa date, time is about 50 minutes. 捏合作用使膏料充分混合均匀,研磨目的使膏料细腻。 The paste kneading action fully mixed, the paste material fine grinding purposes. 捏合、研磨结束后,打出少量的膏体进行检验,合格后,再打入膏体储存锅进行陈化,使物料自然冷却至常温,同时使物料充分膨胀形成均相的粘合体,提高物料的弹性,陈化时间约为120分钟。 Kneading after grinding, a small amount of play paste inspection, after passing into the paste and then subjected to aging storage pot, the material was naturally cooled to room temperature, while the expansion of the adhesive material sufficient to form a homogeneous body, improving material elasticity, aging time is about 120 minutes.

[0086] 在制膏过程中,因捏合、研磨过程会磨擦放热,故在夏季需用夹套冷却水控制温度彡45。 [0086] In the prepared paste process, due to the kneading, friction grinding process will be exothermic, it is required in the summer cooling water temperature control jacket 45 San. . .

[0087] 整个铁皮石斛提取物的加工过程,除瞬间灭菌之外,都在45°C以下完成,充分保留了铁皮石斛中的各种有效成分。 [0087] The entire process Dendrobium extract, in addition to the flash pasteurization, were completed at 45 ° C or less, sufficient to retain the various active ingredients in Dendrobium.

[0088] (五)灌装 [0088] (v) Filling

[0089]本工艺在自动灌装线上完成,装灌过程中要调节好装灌量(装量正偏差在7.5%以内)、封尾温度(120~135°C)和机器速度(30~50次/min),定时检查牙膏重量和封尾质量, 灌装结束后,再经自动装盒、收缩膜热封、装箱等成品后续商业化包装处理,包装过程中注意检查包装材料质量和品种的一致性,并特别要注意防止空管、空盒现象,包装结束后,按品种、时间分类堆放,进行检验,合格后,再入库储存。 [0089] The present process is completed in the automatic filling lines, bottling process to regulate the filled amount (attached amount of 7.5% or less positive bias), sealing temperature (120 ~ 135 ° C) and the machine speed (~ 30 50 times / min), and the weight of the toothpaste regularly check the quality of sealing, after filling, and then the automatic cartoning, shrink film heat sealing, and other finished packing commercial package subsequent treatment, while checking the quality of packaging materials and packaging variety of consistency, and with particular attention to prevent air traffic control, the phenomenon of empty boxes, after the packaging, by species, time classification piled up, tested, qualified, and then stored in storage.

[0090] 由于目前铁皮石斛产品多以内服为主,本发明中的铁皮石斛牙膏拓展了铁皮石斛的应用领域,更为充分地发挥其价值。 [0090] As the current Dendrobium products and more or less based services, Dendrobium toothpaste of the present invention expands the applications Dendrobium, more fully play its value.

[0091] 实施例2。 [0091] Example 2.

[0092]参见图1至图2,本实施例中的铁皮石斛牙膏包括重量份数为40.0~50.0份的山梨糖醇;重量份数为10 . 〇~20.0份的水;重量份数为18.0~22.0份的水合硅石;重量份数为8.0~12.0份的甘油;重量份数为4.0~6.0份的铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质;重量份数为3.0~5.0份的聚乙二醇400;重量份数为1.0~ 2.0份的月桂醇硫酸酯钠;重量份数为0.6~0.8份的羧甲基纤维素钠;重量份数为0.8~1.2 份的食用香精;重量份数为〇. 1~〇. 2份的皱波角叉菜;重量份数为0.1~0.3份的黄原胶;重量份数为〇. 1~〇. 3份的糖精钠;重量份数为0.3~0.5份的黄芩提取物;重量份数为0.3~ 0.5份的三七提取物;重量份数为0.1~0.2份的丹皮酚;重量份数为0.03~0.05份的云母粉;重量份数为〇. 02~0.04份的CI19140;重量份数为0.02~0.04份的CI42090。 [0092] Referring to FIG. 1 to FIG. 2, the present embodiment Dendrobium toothpaste embodiment comprises 40.0 to 50.0 parts by weight of parts of sorbitol; billion parts by weight of 10 to 20.0 parts of water;. 18.0 parts by weight to 22.0 parts of hydrated silica; 8.0 to 12.0 parts by weight parts of glycerol; 4.0 to 6.0 parts by weight of parts of Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins; parts by weight 3.0 to 5.0 parts of polyethylene glycol 400; 1.0 parts by weight to 2.0 parts of sodium lauryl alcohol sulfate ester; parts by weight of 0.6 to 0.8 parts sodium carboxymethylcellulose; 0.8 to 1.2 parts by weight parts of a food flavor;.. ~ 1 billion parts by weight of 2 parts of a square wave of wrinkle carrageenan; 0.1 parts by weight to 0.3 parts of xanthan gum; billion parts by weight of 1 to 3 parts of a square. sodium saccharin; 0.3 parts by weight to 0.5 parts of Scutellaria root extract; 0.3 parts by weight to 0.5 parts by notoginseng extract; 0.1 parts by weight to 0.2 parts by paeonol; 0.03 to 0.05 parts by weight parts of mica powder; ~ 02 parts by weight of 0.04 billion parts CI19140;. 0.02 to 0.04 parts by weight of parts CI42090.

[0093] 其中,铁皮石斛提取物采用如下方法制得:将洗净后的新鲜的铁皮石斛置于沸水中消毒3~5min,取出后置于水中冷却,然后进行切断,将水温2~10°C的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6~1:8,启动均质机且控制出料细度在200 ~300mi以下,得到铁皮石斛提取物母液,对铁皮石斛提取物母液进行过滤得到铁皮石斛提取物。 [0093] wherein, Dendrobium extract prepared as follows: fresh Dendrobium placed in boiling water after washing disinfection 3 ~ 5min, cooling water taken out was placed, and then cut the water 2 ~ 10 ° C and water was placed after cutting homogenizer Dendrobium, Dendrobium weight ratio to water is 1: 6 to 1: 8, and controls the start homogenizer fineness of the material at 200 ~ 300mi less metal to give The mother liquor Dendrobium extract, Dendrobium extract obtained was filtered mother liquors Dendrobium extract.

[0094] 本实施例中铁皮石斛牙膏的配方科学、合理,成分之间会产生协同效应,能够更加有效的发挥出铁皮石斛提取物中多糖、叶绿素、维生素和蛋白质的功效,且更加有利于皮肤吸收铁皮石斛提取物中的多糖、叶绿素、维生素和蛋白质。 [0094] Examples Dendrobium toothpaste formulation science present embodiment, reasonable, will produce a synergistic effect between the components, we can more effectively exert the effect Dendrobium polysaccharide extracts, chlorophyll, vitamins and proteins, and more beneficial to the skin absorption Dendrobium extract polysaccharides, chlorophyll, vitamins and proteins.

[0095] 下面对本发明的铁皮石斛牙膏中各成分的用量再进行举例说明,参见表三。 [0095] Next, the Dendrobium toothpastes of the present invention the quantities of ingredients further illustration, Table III.

[0096] 表三 [0096] Table III

[0097] [0097]

Figure CN104127340BD00111

[0099]备注:表三中的各物质所用的量均为重量份数。 [0099] Note: The amount of each substance in Table III used are parts by weight.

[0100] 本实施例中铁皮石斛牙膏的制备方法依次包括如下工序: [0100] In the present embodiment, Dendrobium toothpaste preparation comprising the steps of sequentially:

[0101] A前处理工序, [0101] A pretreatment step,

[0102] a铁皮石斛原料要求, [0102] a Dendrobium raw material requirements,

[0103]在开花之前采收铁皮石斛,该铁皮石斛原料为三年生长期的铁皮石斛。 [0103] Before flowering harvest Dendrobium, Dendrobium feed the growing period of three years Dendrobium.

[0104] b 杀菌, [0104] b sterilization,

[0105]在200L敞口锅中加入150L纯化水,加热煮沸,铁皮石斛先用自来水冲洗3遍,再用纯化水冲洗2遍,用不锈钢夹将铁皮石斛置沸水中"淬" 3~5min,取出后置纯化水中冷却。 [0105] In an open pot 200L 150L of purified water was added, heated to boiling, Dendrobium rinse 3 times with tap water, purified water, then rinsed 2 times with a stainless steel clip Dendrobium in boiling water "quenching" 3 ~ 5min, postpurifier cooling water taken out. [0106] c 切段, [0106] c cut into sections,

[0107]将铁皮石斛切段。 [0107] The Dendrobium cut into sections.

[0108] B低温超微研磨工序, [0108] B Attritor cryogenic step,

[0109] 将水温2~10°C的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6~1:8,例如铁皮石斛与水的重量比可以为1:6,1:6.5,1:7,1:7.5,1:8,1:6.3,1:6.8, 1: 7.2,1: 7.7等,启动均质机且控制出料细度在200~300m以下,得到铁皮石斛提取物母液。 [0109] The temperature of 2 ~ 10 ° C and water was placed after cutting homogenizer Dendrobium, Dendrobium weight ratio to water is 1: 6 to 1: 8, for example, the weight ratio of water Dendrobium can 1: 6,1: 6.5,: 7,1: 7.5, 1: 8,1: 6.3,1: 6.8, 1: 7.2, 1: 7.7 and the like, and controls the start homogenizer fineness of the material at 200 ~ 300m or less, Dendrobium extract obtained mother liquor.

[0110] c过滤工序,依次包括如下步骤: [0110] c filtration step in turn comprises the steps of:

[0111] a粗滤步骤, [0111] a straining step,

[0112] 将100目尼龙滤布浸湿,折叠成2层平铺于真空抽滤的漏斗内,边缘置于漏斗之外, 开启真空抽滤机,真空度大于〇. 〇7MPa,再将铁皮石斛提取物母液倒入漏斗内,过滤得到的粗滤液,当滤渣厚度达到0.5~lcm时清理一次。 [0112] The wet 100 mesh nylon cloth, to be folded into the inner plated layer 2 by vacuum filtration funnel, the funnel was placed outside the edge, turn vacuum filtration, vacuum is greater than square. 〇7MPa, then iron Dendrobium extract liquor is poured into the funnel, the filtrate was filtered to give the crude, when cleaning a filter cake thickness of 0.5 ~ lcm.

[0113] b精滤步骤, [0113] b fine filtration step,

[0114] 启动高速管式离心机和蠕动栗,高速管式离心机的转速为15000r/min,蠕动栗的转速为150~250r/min,将进料管至粗滤液内,离心过滤后得到铁皮石斛提取物,将铁皮石斛提取物置于药液储存罐内,每离心过滤200~300L清理滤渣一次。 [0114] Start-speed tubular centrifuge and peristaltic Li, high speed centrifuge tube speed of 15000r / min, the speed of the peristaltic Li 150 ~ 250r / min, the crude feed tube into the filtrate obtained after centrifugation metal Dendrobium extract, Dendrobium extract was placed in the liquid storage tank, a centrifugal filter 200 ~ 300L per cake cleanup time.

[0115] 对铁皮石斛提取物母液进行过滤得到铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质。 [0115] Dendrobium extract obtained was filtered mother liquors Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins.

[0116] D制膏工序, [0116] D step paste system,

[0117] 先将配方量的铁皮石斛提取物、黄芩提取物、三七提取物、丹皮酚、山梨糖醇、甘油、聚乙二醇400、皱波角叉菜、月桂醇硫酸酯钠、羧甲基纤维素钠、黄原胶和糖精钠用配方量的水溶解,加入到制膏锅中,再将配方量的水合硅石、云母粉、CI19140和CI42090加入到制膏锅中;添加完毕后,再添加配方量的食用香精,进行刮板搅拌、均质搅拌和研磨,得膏体;打出少量的膏体进行检验,合格后,再打入膏体储存锅进行陈化,陈化时间约为120分钟,使物料自然冷却至常温,同时使物料充分膨胀形成均相的粘合体,提高物料的弹性,从而得铁皮石斛牙膏。 [0117] Formulation amount of the first Dendrobium extract, Scutellaria root extract, Panax extract, Paeonol, sorbitol, glycerin, polyethylene glycol 400, wrinkled wave carrageenan, sodium lauryl alcohol sulfate ester, sodium carboxymethyl cellulose, xanthan gum and sodium saccharin water with the formulation amount of dissolved, was added to the paste pot system, then the formula amount of hydrated silica, mica, CI 19140, and added to the prepared paste pot CI42090; the addition was complete after, add formula amount of food flavors, a scraper stirring, homogeneous mixing and grinding, to obtain paste; play a small amount of paste tested, qualified, and then paste into storage pot were aging, aging time about 120 minutes, the material was naturally cooled to room temperature, while the expanded material sufficient to form a homogeneous bonded body, increase the flexibility of the material, thereby obtaining Dendrobium toothpaste.

[0118] 在气温较高的时候,如夏季的时候,在进行刮板搅拌、均质搅拌和研磨时,通常采用夹套冷却水控制温度在45°C以下。 [0118] when the temperature is higher, such as summer time, when the stirring blade, and grinding the homogeneous stirring is performed, usually at a temperature controlled water jacket cooling 45 ° C or less.

[0119] E灌装工序, [0119] E filling step,

[0120] 在自动灌装线上完成,装灌过程中调节好装灌量、封尾温度和机器速度,定时检查牙膏重量和封尾质量。 [0120] In the automatic completion of the filling line, during the bottling regulate filled amount, temperature and sealing machine speed, by weight of the toothpaste and regularly check the quality of sealing. 通常情况下,装灌过程中要调节好装灌量(装量正偏差在7.5%以内)、封尾温度(120~135°C)和机器速度(30~50次/min),定时检查牙膏重量和封尾质量, 灌装结束后,再经自动装盒、收缩膜热封、装箱等成品后续商业化包装处理,包装过程中注意检查包装材料质量和品种的一致性,并特别要注意防止空管、空盒现象,包装结束后,按品种、时间分类堆放,进行检验,合格后,再入库储存。 Typically, the bottling process to regulate the filled amount (attached amount of positive deviation less than 7.5%), sealing temperature (120 ~ 135 ° C) and the machine speed (30 to 50 times / min), regular check toothpaste weight and quality of sealing, after filling, and then the automatic cartoning, shrink film heat sealing, and other finished packing commercial package subsequent process, the packaging process while checking the consistency of the quality and variety of packaging materials, and particular attention prevent air traffic control, the phenomenon of empty boxes, after the packaging, by species, time classification piled up, tested, qualified, and then stored in storage.

[0121] 本发明还涉及一种由上述制备方法制得的铁皮石斛牙膏,采用上述制备方法制得的铁皮石斛牙膏可以直接用于口腔中,铁皮石斛中的多糖、叶绿素、维生素和蛋白质等成分可通过皮肤被人体吸收,可为皮肤提供非常丰富的营养,拓展了铁皮石斛的应用领域,更为充分地发挥其价值。 [0121] The present invention further relates to a method for preparing the above toothpastes Dendrobium obtained using the above method for preparing toothpaste Dendrobium obtained can be directly used in the mouth, Dendrobium polysaccharide, chlorophyll, vitamins and proteins and other ingredients can be absorbed through the skin, it can provide a wealth of nutrition for the skin, expanding the application fields Dendrobium, more fully play its value.

[0122] 本实施例中整个铁皮石斛提取物的加工过程,除瞬间灭菌之外,都在30°C以下完成,即便是在铁皮石斛牙膏的加工过程,其温度也控制在45°C以下,充分保留了铁皮石斛中的各种有效成分。 [0122] Examples entire process Dendrobium extract of the present embodiment, in addition to the flash pasteurization, are created below 30 ° C, even in the process of Dendrobium toothpaste, which is also controlled at a temperature of 45 ° C or less , fully retains the various active ingredients in Dendrobium. 该铁皮石斛牙膏的制备方法尽可能的保留了铁皮石斛的有效成分,以铁皮石斛鲜品为原料进行低温萃取,省去传统铁皮楓斗的烘干工序,有效成分不易被破坏,所得产品中多糖、维生素、叶绿素、游离氨基酸等含量高;采用低温萃取技术,将铁皮石斛多糖、石斛碱、氨基酸最大程度萃取出来,同时保护铁皮石斛中叶绿素、维生素以及活性酶等成分免受高温破坏。 The method for preparing toothpaste Dendrobium retained as an active ingredient of Dendrobium, Dendrobium to fresh products as raw material for low-temperature extraction, eliminating the traditional drying step Dendrobium, the active ingredient is not easily destroyed, the resulting polysaccharide product , high levels of vitamins, chlorophyll, free amino acids; low temperature extraction, the extracted polysaccharide Dendrobium, Dendrobium bases, amino acids out of the maximum extent, while protecting Dendrobium chlorophyll, vitamins and enzymes active ingredient from heat damage.

[0123]虽然本发明已以实施例公开如上,但其并非用以限定本发明的保护范围,任何熟悉该项技术的技术人员,在不脱离本发明的构思和范围内所作的更动与润饰,均应属于本发明的保护范围。 [0123] While the invention has been disclosed in the above embodiments, but not intended to limit the scope of the present invention, any person skilled in the art in the art, without departing from the modifications and variations made within the spirit and scope of the invention , it should belong to the scope of the present invention.

Claims (8)

1. 一种铁皮石斛牙膏,其特征在于:该铁皮石斛牙膏包括重量份数为40.0~50.0份的山梨糖醇;重量份数为10. 〇~20.0份的水;重量份数为18.0~22.0份的水合硅石;重量份数为8.0~12.0份的甘油;重量份数为4.0~6.0份的铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质;重量份数为3.0~5.0份的聚乙二醇400;重量份数为1.0 ~2.0份的月桂醇硫酸酯钠;重量份数为0.6~0.8份的羧甲基纤维素钠;重量份数为0.8~ 1.2份的食用香精;重量份数为0.1~0.2份的皱波角叉菜;重量份数为0.1~0.3份的黄原胶;重量份数为〇. 1~〇. 3份的糖精钠;重量份数为0.3~0.5份的黄芩提取物;重量份数为0.3~0.5份的三七提取物;重量份数为0.1~0.2份的丹皮酚;重量份数为0.03~0.05份的云母粉;重量份数为〇. 02~0.04份的CI19140;重量份数为0.02~0.04份的CI42090;所述铁皮石斛提取物采用如下方法制得:将洗净后的新 A Dendrobium toothpaste, characterized in that: the Dendrobium dentifrice comprising 40.0 to 50.0 parts by weight parts of sorbitol; billion parts by weight of 10 parts water to 20.0; 18.0 to 22.0 parts by weight parts of a hydrated silica; 8.0 to 12.0 parts by weight parts of glycerol; 4.0 to 6.0 parts by weight of parts of Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins; 3.0 parts by weight of to 5.0 parts of polyethylene glycol 400; lauryl alcohol sulfate sodium 1.0 parts by weight to 2.0 parts; the parts by weight of 0.6 to 0.8 parts sodium carboxymethylcellulose; parts by weight of 0.8 to 1.2 parts food flavor; 0.1 parts by weight to 0.2 parts by corrugated wave carrageenan; 0.1 parts by weight to 0.3 parts of xanthan gum; billion parts by weight of 1 to 3 billion parts of sodium saccharin;. by weight extraction of 0.3 to 0.5 parts by skullcap thereof; 0.3 parts by weight to 0.5 parts by notoginseng extract; 0.1 parts by weight to 0.2 parts by paeonol; 0.03 to 0.05 parts by weight of mica parts; weight 0.04 parts of 02 billion parts of CI 19140; parts by weight of 0.02 to 0.04 parts of CI 42090; the Dendrobium extract prepared as follows: after washing new 的铁皮石斛置于沸水中消毒3~5min,取出后置于水中冷却,然后进行切断,将水温2~10°C的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6~1:8,启动均质机且控制出料细度在200~300μπι,得到铁皮石斛提取物母液,对铁皮石斛提取物母液进行过滤得到铁皮石斛提取物。 Dendrobium placed in boiling water disinfection 3 ~ 5min, cooling water taken out was placed, and then cut, Dendrobium water temperature after the 2 ~ 10 ° C was placed in a homogenizer and off, and water Dendrobium a weight ratio of 1: 6 to 1: 8, and controls the start homogenizer fineness of the material at 200 ~ 300μπι, Dendrobium extract obtained mother liquor, the mother liquor Dendrobium extract obtained was filtered Dendrobium extract.
2. -种铁皮石斛牙膏的制备方法,其特征在于:所述铁皮石斛牙膏包括重量份数为40.0~50.0份的山梨糖醇;重量份数为10.0~20.0份的水;重量份数为18.0~22.0份的水合硅石;重量份数为8.0~12.0份的甘油;重量份数为4.0~6.0份的铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质;重量份数为3.0~5.0份的聚乙二醇400;重量份数为1.0~2.0份的月桂醇硫酸酯钠;重量份数为0.6~0.8份的羧甲基纤维素钠;重量份数为〇. 8~1.2份的食用香精;重量份数为0.1~0.2份的皱波角叉菜;重量份数为0.1~0.3份的黄原胶;重量份数为0.1~0.3份的糖精钠;重量份数为0.3~0.5份的黄芩提取物;重量份数为〇. 3~0.5份的三七提取物;重量份数为0.1~0.2份的丹皮酚;重量份数为0.03~0.05份的云母粉;重量份数为0.02~0.04份的CI19140;重量份数为0.02~0.04份的CI42090;所述制备方法依次包括如下工序: Α前处理工序 2. - The method of producing Dendrobium toothpaste, characterized in that: said Dendrobium dentifrice comprising 40.0 to 50.0 parts by weight parts of sorbitol; 10.0 to 20.0 parts by weight parts of water; 18.0 parts by weight to 22.0 parts of hydrated silica; 8.0 to 12.0 parts by weight parts of glycerol; 4.0 to 6.0 parts by weight of parts of Dendrobium extract, Dendrobium extract, which contains polysaccharides, chlorophyll, vitamins and proteins; parts by weight 3.0 to 5.0 parts of polyethylene glycol 400; 1.0 parts by weight to 2.0 parts of sodium lauryl alcohol sulfate ester; parts by weight of 0.6 to 0.8 parts sodium carboxymethylcellulose; 8 parts by weight of square. to 1.2 parts of a food flavor; 0.1 parts by weight to 0.2 parts by corrugated wave carrageenan; 0.1 parts by weight to 0.3 parts of xanthan gum; 0.1 parts by weight to 0.3 parts of sodium saccharin; parts by weight extraction of 0.3 to 0.5 parts by skullcap thereof; billion parts by weight of 3 to 0.5 parts by notoginseng extract;. 0.1 parts by weight to 0.2 parts by paeonol; 0.03 to 0.05 parts by weight of mica parts ; parts by weight of 0.02 to 0.04 parts CI 19140; parts by weight of 0.02 to 0.04 parts of CI 42090; the manufacturing method sequentially comprising the following steps: Α pretreatment step a铁皮石斛原料要求, 在开花之前采收铁皮石斛; b杀囷, 洗净后的新鲜的铁皮石斛置于沸水中消毒3~5min,取出后置于水中冷却; c切段, 将铁皮石斛切段; B低温超微研磨工序, 将水温2~10°C的水和切断后的铁皮石斛置于均质机中,铁皮石斛与水的重量比为1:6 ~1:8,启动均质机且控制出料细度在200~300μπι以下,得到铁皮石斛提取物母液; C过滤工序, 对铁皮石斛提取物母液进行过滤得到铁皮石斛提取物,该铁皮石斛提取物中含有多糖、叶绿素、维生素和蛋白质;所述C过滤工序依次包括如下步骤: a粗滤步骤, 将100目尼龙滤布浸湿,折叠成2层平铺于真空抽滤的漏斗内,边缘置于漏斗之外,开启真空抽滤机,真空度大于0 . 〇7MPa,再将铁皮石斛提取物母液倒入漏斗内,过滤得到的粗滤液,当滤渣厚度达到Ο · 5~lcm时清理一次; b精滤步骤, 启动高速管 a raw material requirements Dendrobium, Dendrobium harvested before flowering; B granary kill fresh Dendrobium placed in boiling water after washing disinfection 3 ~ 5min, cooling water taken out is placed; C and cut into sections, the cut Dendrobium segment; Dendrobium low attritor after step B, the water temperature of 2 ~ 10 ° C and placed in a homogenizer cutting, the weight ratio of Dendrobium and water is 1: 6 to 1: 8, homogeneous starting machine and control fineness of the material at 200 ~ 300μπι or less, to obtain Dendrobium extract liquor; C filtration step, Dendrobium extract liquor obtained by filtration, Dendrobium extract, the Dendrobium extract contains polysaccharides, chlorophyll, vitamins and protein; the filtration step C comprises the steps of sequentially: a coarse filtration step, the 100-mesh nylon cloth soaked in folded into the inner plated layer 2 by vacuum filtration funnel, the funnel edge disposed outside the vacuum is applied filtration, vacuum 〇7MPa greater than 0, then Dendrobium extract liquor was poured into the funnel, the filtrate was filtered to give the crude, when cleaning a filter cake thickness reaches Ο · 5 ~ lcm;. b fine filtration step, high-speed start tube 式离心机和蠕动栗,高速管式离心机的转速为15000r/min,蠕动栗的转速为150~250r/min,将进料管至粗滤液内,离心过滤后得到铁皮石斛提取物,将铁皮石斛提取物置于药液储存罐内,每离心过滤200~300L清理滤渣一次; D制膏工序, 先将配方量的铁皮石斛提取物、黄芩提取物、三七提取物、丹皮酚、山梨糖醇、甘油、聚乙二醇400、皱波角叉菜、月桂醇硫酸酯钠、羧甲基纤维素钠、黄原胶和糖精钠用配方量的水溶解,加入到制膏锅中,再将配方量的水合硅石、云母粉、CI19140和CI42090加入到制膏锅中;添加完毕后,再添加配方量的食用香精,进行刮板搅拌、均质搅拌和研磨,得膏体;打出少量的膏体进行检验,合格后,再打入膏体储存锅进行陈化,使物料自然冷却至常温,同时使物料充分膨胀形成均相的粘合体,提高物料的弹性,从而得铁皮石斛牙膏; E灌装 Centrifuge and peristaltic Li, high speed centrifuge tube speed of 15000r / min, the speed of the peristaltic Li 150 ~ 250r / min, the crude feed tube into the filtrate obtained after centrifugation Dendrobium extract, the iron Dendrobium extract liquid storage tank is placed, each centrifugal filtration residue 200 ~ 300L cleaning time; D manufactured by kneading process, the amount of first formulation Dendrobium extract, Scutellaria root extract, Panax extract, paeonol, sorbose alcohols, glycerol, polyethylene glycol 400, wrinkled wave carrageenan, sodium lauryl alcohol sulfate ester, sodium carboxymethyl cellulose, xanthan gum and sodium saccharin water with the formulation amount of dissolved, was added to the paste pot system, and then the formula amount of hydrated silica, mica, CI 19140, and added to the prepared paste pot CI42090; after the addition was complete, add formula amount of flavor composition, a stirring blade, a homogeneous stirring and grinding to obtain a paste; a small amount of play paste inspection, after passing into the paste and then subjected to aging storage pot, the material was naturally cooled to room temperature, while the expanded material sufficient to form a homogeneous bonded body, increase the flexibility of the material, thereby obtaining a toothpaste Dendrobium; E filling 序, 将铁皮石斛牙膏进行灌装。 Sequence, the Dendrobium for filling toothpaste.
3. 根据权利要求2所述的铁皮石斛牙膏的制备方法,其特征在于:所述A前处理工序的a 铁皮石斛原料要求中,铁皮石斛原料为三年生长期的铁皮石斛。 The production method according Dendrobium toothpaste according to claim 2, wherein: a raw material requirements Dendrobium before the treatment step A, the raw material for the three growth Dendrobium Dendrobium.
4. 根据权利要求2所述的铁皮石斛牙膏的制备方法,其特征在于:所述A前处理工序的b 杀菌中,在200L敞口锅中加入150L纯化水,加热煮沸,铁皮石斛先用自来水冲洗3遍,再用纯化水冲洗2遍,用不锈钢夹将铁皮石斛置沸水中"淬" 3~5min,取出后置纯化水中冷却。 4. A method for preparing the Dendrobium toothpaste according to claim 2, wherein: said sterilizing pretreatment step b in A, purified water was added to 150L in 200L open pot, heated to boiling, with tap Dendrobium rinse 3 times, 2 times and then purified water rinse, the Dendrobium in boiling water "quenching" 3 ~ 5min, then cool the rear of purified water with a stainless steel clip.
5. 根据权利要求2所述的铁皮石斛牙膏的制备方法,其特征在于:所述D制膏工序中,陈化时间为120分钟。 The preparation method according Dendrobium toothpaste according to claim 2, wherein: said step D paste system, the aging time is 120 minutes.
6. 根据权利要求2所述的铁皮石斛牙膏的制备方法,其特征在于:所述D制膏工序中,在进行刮板搅拌、均质搅拌和研磨时,采用夹套冷却水控制温度在45°C以下。 The production method according Dendrobium toothpaste according to claim 2, wherein: said step D the paste prepared, the blade during stirring, stirring and homogenizing grinding, using jacket cooling water temperature controlled at 45 ° C.
7. 根据权利要求2所述的铁皮石斛牙膏的制备方法,其特征在于:所述E灌装工序,在自动灌装线上完成,装灌过程中调节好装灌量、封尾温度和机器速度,定时检查牙膏重量和封尾质量。 7. A method for preparing the Dendrobium toothpaste according to claim 2, wherein: said filling step E, to complete the automatic filling line, during the bottling regulate filled amount, temperature and sealing machine speed, weight and toothpaste regularly check the quality of sealing.
8. -种铁皮石斛牙膏,其特征在于:该铁皮石斛牙膏采用如权利要求2-7任一权利要求所述的制备方法制备而成。 8. - Dendrobium species of toothpaste, characterized in that: the use of Dendrobium toothpaste as claimed in claim prepared by the production method according to any one of claims 2-7.
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