CN104116592A - Dressing with nano-zinc oxide composite antibiosis layer - Google Patents

Dressing with nano-zinc oxide composite antibiosis layer Download PDF

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Publication number
CN104116592A
CN104116592A CN201310145758.XA CN201310145758A CN104116592A CN 104116592 A CN104116592 A CN 104116592A CN 201310145758 A CN201310145758 A CN 201310145758A CN 104116592 A CN104116592 A CN 104116592A
Authority
CN
China
Prior art keywords
layer
zinc oxide
nano
base cloth
oxide composite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310145758.XA
Other languages
Chinese (zh)
Inventor
田东奎
何磊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Pharmacn Medical Technology Co Ltd
Original Assignee
Tianjin Pharmacn Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Pharmacn Medical Technology Co Ltd filed Critical Tianjin Pharmacn Medical Technology Co Ltd
Priority to CN201310145758.XA priority Critical patent/CN104116592A/en
Publication of CN104116592A publication Critical patent/CN104116592A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/023Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A61F13/0236Adhesive bandages or dressings wound covering film layers without a fluid retention layer characterised by the application/handling support layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Provided is a dressing with a nano-zinc oxide composite antibiosis layer. The dressing is provided with a base cloth (1). An adhering layer (2) is arranged on the inner face of the base cloth in a coating mode. A protecting layer (3) is pasted on the middle adhering layer of the base cloth. Release paper (4) is arranged on the protecting layer. The outer edge of the release paper is fixed on a corresponding exposed part on the periphery of the base cloth. The dressing is characterized in that the protecting layer is divided into three layers which are a nano-zinc oxide composite layer (3.1), a spongy fabric layer (3.2) and a non-woven fabric reinforcing layer (3.3) in sequence from the position near the base cloth to the position far from the base cloth, the thickness of the nano-zinc oxide composite layer is 0.5 mm- 1mm, the nano-zinc oxide composite layer is formed by the fact that nano-zinc oxide particles (3.12) are evenly arranged on a polymer base (3.11) in a coating mode, the D90 particle diameter of the nano-zinc oxide particles is 30 nm-50 nm, polylactic acid is used on the polymer base, and the nano-zinc oxide particles are fixed on the polymer base in an adhesive-bonding or heating-fixing mode.

Description

A kind of dressing with nanometer zinc oxide composite antibiosis layer
Invention field
The present invention relates to a kind of medical dressing.
Background technology
Medical dressing generally comprises adhesive-layer, base cloth and protective layer, and it is covered on wound surface by protective layer, stops the further infection of wound.By improving composition, the structure of protective layer, improve its infection promoting healing effect and become problem to be solved in prior art.
Nano zine oxide, be widely used in externally used antimicrobial antiinflammatory field as novel nano medical material, but nano material has it to use limitation, skin surface has breakage, nanoparticle enters human body, thereby easily stimulate the immune system of human body to produce potential untoward reaction, these defects have limited the application of the medical nano material including nano zine oxide greatly.
Summary of the invention:
The invention provides a kind of dressing with nanometer zinc oxide composite antibiosis layer, there is base cloth 1, base cloth inner face is coated with adhesive-layer 2, on the adhesive-layer of base cloth middle part, be pasted with protective layer 3, on protective layer, be covered with from paper 4, be fixed on the exposed parts that base cloth periphery is corresponding from paper outer rim, it is characterized in that described protective layer is divided into three layers, comply with apart from base cloth by the nearly nano zine oxide composite bed 3.1 that is extremely far followed successively by, spongy tissue layer 3.2, non-woven fabrics enhancement Layer 3.3, described nano zine oxide composite bed thickness is 0.5-1mm, form by the mode that is evenly coated with nano zinc oxide particles 3.12 in polymeric substrates 3.11, the D90 particle diameter of described nano zinc oxide particles is 30-50nm.Described polymeric substrates preferably adopts polylactic acid, and nano zinc oxide particles is fixed in polymeric substrates by bonding or heating fixed form.
Dressing provided by the present invention; adopt composite protection layer; in sponge tissue layer bottom, be provided with nano zine oxide composite bed, in order to prevent the excessive release of nano zine oxide; can give full play to again its antibacterial action; the dressing of making like this, after wrapping, can discharge nano zine oxide slowly; can continue to bring into play antibacterial action, therefore can wrap up for a long time without changing dressings.
Brief description of the drawings:
Fig. 1 is for the invention provides dressing overall structure schematic diagram
Fig. 2 is protective layer internal structure schematic diagram
Detailed description of the invention
The present invention is further illustrated by reference to the accompanying drawings now.The schematic diagram that these accompanying drawings are simplification only illustrates basic structure of the present invention in a schematic way, and therefore it only shows the formation relevant with the present invention, can not be interpreted as the restriction to embodiment of the present invention.
Dressing as shown in Figure 1, has adhesive-layer 2 on base cloth 1, on base cloth 1 middle part adhesive-layer 2, be pasted with overcoat 3, is coated with from paper 4 on protective layer 3, is fixed on the exposed parts that base cloth 1 periphery is corresponding from paper 4 outer rims.
Protective layer internal structure as shown in Figure 2, comply with apart from base cloth 1 by the nearly nano zine oxide composite bed 3.1, spongy tissue layer 3.2, non-woven fabrics enhancement Layer 3.3 of being extremely far followed successively by by described protective layer 3.Nano zine oxide composite bed is divided into polymeric substrates 3.11 and applies the nano zinc oxide particles 3.12 on it.

Claims (1)

1. one kind has the dressing of nanometer zinc oxide composite antibiosis layer, there is base cloth (1), base cloth inner face is coated with adhesive-layer (2), on the adhesive-layer of base cloth middle part, be pasted with protective layer (3), on protective layer, be covered with from paper (4), be fixed on the exposed parts that base cloth periphery is corresponding from paper outer rim, it is characterized in that described protective layer is divided into three layers, comply with apart from base cloth by the nearly nano zine oxide composite bed (3.1) that is extremely far followed successively by, spongy tissue layer (3.2), non-woven fabrics enhancement Layer (3.3), described nano zine oxide composite bed thickness is 0.5-1mm, by forming in the upper evenly mode of coating nano zinc oxide particles (3.12) of polymeric substrates (3.11), the D90 particle diameter of described nano zinc oxide particles is 30-50nm, described polymeric substrates adopts polylactic acid, nano zinc oxide particles is fixed in polymeric substrates by bonding or heating fixed form.
CN201310145758.XA 2013-04-25 2013-04-25 Dressing with nano-zinc oxide composite antibiosis layer Pending CN104116592A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310145758.XA CN104116592A (en) 2013-04-25 2013-04-25 Dressing with nano-zinc oxide composite antibiosis layer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310145758.XA CN104116592A (en) 2013-04-25 2013-04-25 Dressing with nano-zinc oxide composite antibiosis layer

Publications (1)

Publication Number Publication Date
CN104116592A true CN104116592A (en) 2014-10-29

Family

ID=51762377

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310145758.XA Pending CN104116592A (en) 2013-04-25 2013-04-25 Dressing with nano-zinc oxide composite antibiosis layer

Country Status (1)

Country Link
CN (1) CN104116592A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107583095A (en) * 2017-08-08 2018-01-16 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of antimicrobial form fracture anchor stone cream bandage and products thereof and application

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107583095A (en) * 2017-08-08 2018-01-16 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of antimicrobial form fracture anchor stone cream bandage and products thereof and application

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C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20141029