CN104020264A - Bionic digestion device for gastrointestinal tracts - Google Patents

Bionic digestion device for gastrointestinal tracts Download PDF

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Publication number
CN104020264A
CN104020264A CN201410289798.6A CN201410289798A CN104020264A CN 104020264 A CN104020264 A CN 104020264A CN 201410289798 A CN201410289798 A CN 201410289798A CN 104020264 A CN104020264 A CN 104020264A
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simulation
glass tube
digester
damping fluid
digestion
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CN201410289798.6A
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CN104020264B (en
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邓耀辉
陈开宇
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This Intelligent Development In Science And Technology Co Ltd In Hunan
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This Intelligent Development In Science And Technology Co Ltd In Hunan
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Abstract

The invention provides a bionic digestion device for gastrointestinal tracts and relates to the field of a biological experiment instrument. The bionic digestion device comprises a bracket, a plurality of simulated digesters and a multi-pore-position testing clip, wherein the plurality of simulated digesters are clamped on the multi-pore-position testing clip; the multi-pore-position testing clip is fixedly mounted on the bracket; each simulated digester is provided with a buffering solution input opening, a buffering solution output opening and a digestion solution input opening; in the adjacent two simulated digesters, the buffering solution input opening of the front simulated digester is connected with the buffering solution output opening of the other simulated digester through an infusion hose; the simulated digesters are sequentially connected in series by using the infusion hose. The bionic digestion device for the gastrointestinal tracts can be matched with an automatic enzyme adding device, a buffering solution supplying device, a table concentrator device and the like to realize the automation of a simulated digestion reaction process.

Description

A kind of intestines and stomach Bionic digestion device
Technical field
The present invention relates to Bioexperiment instrument field, especially relate to a kind of intestines and stomach Bionic digestion device.
Background technology
In modern farming, the objective nutrient biological value of accurately evaluating feedstuff is the primary decision-making basis of determining Animal nutrition requirement and optimizing feed formula.From the sixties in 20th century, people are attempting the digestion in animal gastrointestinal tract by conditions in vitro Imitating feed always and are realizing the rapid evaluation to feed nutrient biological value.
In prior art, conventionally adopt triangular flask or test tube as intestines and stomach Bionic digestion device.While simulating digestion experiment, first the feed of constant weight is packed in triangular flask or test tube, then in triangular flask or test tube, add simulated gastric fluid or intestinal juice, again, triangular flask or test tube are placed on to vibration digestion a period of time on water bath with thermostatic control shaking table, this process is the digestion process of simulated animal stomach or intestines, after digestion finishes, centrifugal or filter to isolate and digest material and undigested material again, when the weight of undigested material is higher with respect to the weight of Feed Sample, represent that digestibility is low.While adopting triangular flask or test tube as intestines and stomach Bionic digestion device, because the digestion product in triangular pipe or test tube has inhibiting effect to digestion reaction, cause the digestive efficiency of this analoglike digestion experiment conventionally low than the measured value in animal body, the precisetest of impact to feed nutrient biological value.
In addition, it is too much that existing intestines and stomach Bionic digestion device exists manual steps, the defect that automaticity is not high.
Summary of the invention
Technical matters to be solved by this invention is, a kind of intestines and stomach Bionic digestion device is provided, and it can match with automatic enzyme-added device, damping fluid feedway, shaking table device etc., realizes the robotization of simulation digestion reaction process.
The technical scheme that the present invention solves its technical matters employing is: a kind of intestines and stomach Bionic digestion device, comprise a support, a plurality of simulation digester, a multi-hole position test tube clamp, described a plurality of simulation digester is clamped on described multi-hole position test tube clamp, and described multi-hole position test tube clamp is fixedly mounted on described support; Described in each, simulate digester and be provided with damping fluid input port, damping fluid delivery outlet and digestive juice input port; In two adjacent simulation digesters, the damping fluid input port of a forward simulation digester is connected by infusion tube with the damping fluid delivery outlet of another simulation digester, and all simulation digesters are connected successively by described infusion tube.
Further, described multi-hole position test tube clamp is provided with train wheel bridge and lower plate, the two ends of described train wheel bridge and lower plate are provided with the snap close cooperatively interacting, the end face being in contact with one another between described train wheel bridge and lower plate is provided with the clamp groove that a plurality of shapes and described simulation digester adapt, and is also provided with the cushion course that shape and clamp groove adapt in the clamp groove of described train wheel bridge and lower plate.
Further, described support is by a sheet metal bending forming; Support comprises the support board of a level and the back up pad of two settings; Described two back up pads are positioned at the below of described support board, and are connected with the rear and front end one of support board; Described support board is provided with two exhausting holes that are parallel to each other; The baffle plate that the right edge of support board is erect along upwards bending formation, the upper end of described baffle plate is connected with the ceiling of being made by PVC material, and described ceiling is provided with groove; In described two back up pads, be equipped with the latch with reset button; The lower end of two back up pads all upwards bends the fixed head of formation level, and described fixed head is provided with pilot hole.
Further, described simulation digester comprises glass tube and dialysis tubing, the two ends of described glass tube are respectively provided with a ground, the below, right side of glass tube is provided with inlet branch, the top, left side of glass tube is provided with output arm, described inlet branch is described damping fluid input port, and described output arm is described damping fluid delivery outlet; Described dialysis tubing is positioned at described glass tube, and the two ends of dialysis tubing are stretched out and turn up from two grounds of glass tube respectively, and the dialysis tubing end that is exposed to ground outside of turning up is tied up and is fixed on ground by rubber bar; Two grounds tying up behind dialysis tubing end are plugged with respectively a rubber plug, the rubber plug that is positioned at described glass tube right side is provided with digestive juice flexible pipe, the middle part of described digestive juice flexible pipe is provided with retaining valve, and the end of digestive juice flexible pipe is provided with rapid-acting coupling, and described rapid-acting coupling is described digestive juice input port.
Good effect of the present invention is: during (1) simulation digestion reaction process, this intestines and stomach Bionic digestion device is fixedly mounted on shaking table device by support, digestive juice input port is connected with automatic enzyme-added device, damping fluid input port is connected with damping fluid feedway, thereby can realizes the robotization of simulating digestion reaction process; (2) in preferred version, simulation digester comprises glass tube and dialysis tubing, dialysis tubing is positioned at glass tube, during experiment, feed is placed in dialysis tubing, digestive juice directly enters in dialysis tubing through digestive juice flexible pipe, with feed generation digestion reaction, digestion product diffuses out from dialysis tubing, enter in the damping fluid between dialysis tubing and glass tube, along with flowing of damping fluid, taken out of simulation digester, thereby reduced the inhibiting effect of digestion product to digestion reaction, improved the accuracy of test and appraisal feed nutrient biological value.
Accompanying drawing explanation
Fig. 1 is the schematic perspective view of one embodiment of the invention;
Fig. 2 is the schematic perspective view of multi-hole position test tube clamp embodiment illustrated in fig. 1;
Fig. 3 is the schematic perspective view of support embodiment illustrated in fig. 1;
Fig. 4 is the schematic perspective view of simulation digester embodiment illustrated in fig. 1;
Fig. 5 is the structural representation of simulation digester embodiment illustrated in fig. 1.
Embodiment
Below in conjunction with drawings and Examples, the invention will be further described.
As shown in Fig. 1~5, the present embodiment comprises that a support 3, five simulation digesters 1,2, five simulation digesters 1 of multi-hole position test tube clamp are clamped on multi-hole position test tube clamp 2, and multi-hole position test tube clamp 2 is fixedly mounted on support 3.
Multi-hole position test tube clamp 2 is provided with train wheel bridge 5 and lower plate 6, the two ends of train wheel bridge 5 and lower plate 6 are provided with the snap close 9 cooperatively interacting, the end face being in contact with one another between train wheel bridge 5 and lower plate 6 is provided with a plurality of shapes and the clamp groove 7 that simulation digester 1 adapts, and is also provided with the cushion course 8 that shape and clamp groove 7 adapt in the clamp groove 7 of train wheel bridge 5 and lower plate 6.
Support 3 is by a sheet metal bending forming; Support 3 comprises the support board 10 of a level and the back up pad 16 of two settings; Two back up pads 16 are positioned at the below of support board 10, and are connected with the rear and front end one of support board 10; Support board 10 is provided with two exhausting holes 12 and a plurality of screw 13 being parallel to each other, and the top of screw 13 fixed installation support boards 10 is passed in the bottom of lower plate 6 by screw; The baffle plate 15 that the right edge of support board 10 is erect along upwards bending formation, the upper end of baffle plate 15 is connected with the ceiling 11 of being made by PVC material, and ceiling 11 is provided with groove 14; In two back up pads 16, be equipped with the latch 19 with reset button, its top is also provided with a pair of handle 17; The lower end of two back up pads 16 all upwards bends the fixed head 20 of formation level, and fixed head 20 is provided with pilot hole 18.
Simulation digester 1 comprises glass tube 25 and dialysis tubing 26, the two ends of glass tube 25 are respectively provided with a ground 27, the below, right side of glass tube 25 is provided with inlet branch 28, the top, left side of glass tube 25 is provided with output arm 24, inlet branch 28 is damping fluid input port, and output arm 24 is damping fluid delivery outlet; Dialysis tubing 26 is positioned at glass tube 25, and the two ends of dialysis tubing 26 are stretched out and turn up from two grounds 27 of glass tube 25 respectively, and dialysis tubing 26 ends that are exposed to ground 27 outsides of turning up are tied up by rubber bar and are fixed on ground 27; Two grounds 27 tying up behind dialysis tubing 26 ends are plugged with respectively a rubber plug 29, the rubber plug 29 that is positioned at glass tube 25 right sides is provided with digestive juice flexible pipe 23, the middle part of digestive juice flexible pipe 23 is provided with retaining valve 22, the end of digestive juice flexible pipe 23 is provided with rapid-acting coupling 21, and rapid-acting coupling 21 is digestive juice input port.
In two adjacent simulation digesters 1, the damping fluid input port of a forward simulation digester 1 (inlet branch 28) is connected through through hole 12 by infusion tube 4 with the damping fluid delivery outlet (output arm 24) of another simulation digester 1, and all simulation digesters 1 are connected successively by infusion tube 4.
During experiment, whole device is fixed on shaking table device by the pilot hole 18 on support 3 and latch 19, the infusion tube 4 that damping fluid feedway is connected by the inlet branch 28 with leaning on most the simulation digester 1 of rear side is carried damping fluids to five simulation digesters, simultaneously, automatic enzyme-added device provides digestive ferment by the digestive juice flexible pipe 23 of each simulation digester to simulation digester, thereby can realize the robotization of simulation digestion reaction process.On the other hand, simulation digester comprises glass tube and dialysis tubing, dialysis tubing is positioned at glass tube, during experiment, feed is placed in dialysis tubing, digestive juice directly enters in dialysis tubing through digestive juice flexible pipe, with feed generation digestion reaction, digestion product diffuses out from dialysis tubing, enter in the damping fluid between dialysis tubing and glass tube, along with flowing of damping fluid, taken out of simulation digester, thereby reduced the inhibiting effect of digestion product to digestion reaction, improved the accuracy of test and appraisal feed nutrient biological value.

Claims (4)

1. an intestines and stomach Bionic digestion device, it is characterized in that, comprise a support, a plurality of simulation digester, a multi-hole position test tube clamp, described a plurality of simulation digesters are clamped on described multi-hole position test tube clamp, and described multi-hole position test tube clamp is fixedly mounted on described support; Described in each, simulate digester and be provided with damping fluid input port, damping fluid delivery outlet and digestive juice input port; In two adjacent simulation digesters, the damping fluid input port of a forward simulation digester is connected by infusion tube with the damping fluid delivery outlet of another simulation digester, and all simulation digesters are connected successively by described infusion tube.
2. intestines and stomach Bionic digestion device according to claim 1, it is characterized in that, described multi-hole position test tube clamp is provided with train wheel bridge and lower plate, the two ends of described train wheel bridge and lower plate are provided with the snap close cooperatively interacting, the end face being in contact with one another between described train wheel bridge and lower plate is provided with the clamp groove that a plurality of shapes and described simulation digester adapt, and is also provided with the cushion course that shape and clamp groove adapt in the clamp groove of described train wheel bridge and lower plate.
3. intestines and stomach Bionic digestion device according to claim 2, is characterized in that, described support is by a sheet metal bending forming; Support comprises the support board of a level and the back up pad of two settings; Described two back up pads are positioned at the below of described support board, and are connected with the rear and front end one of support board; Described support board is provided with two exhausting holes that are parallel to each other; The baffle plate that the right edge of support board is erect along upwards bending formation, the upper end of described baffle plate is connected with the ceiling of being made by PVC material, and described ceiling is provided with groove; In described two back up pads, be equipped with the latch with reset button; The lower end of two back up pads all upwards bends the fixed head of formation level, and described fixed head is provided with pilot hole.
4. according to the intestines and stomach Bionic digestion device described in claim 1 or 2 or 3, it is characterized in that, described simulation digester comprises glass tube and dialysis tubing, the two ends of described glass tube are respectively provided with a ground, the below, right side of glass tube is provided with inlet branch, the top, left side of glass tube is provided with output arm, and described inlet branch is described damping fluid input port, and described output arm is described damping fluid delivery outlet; Described dialysis tubing is positioned at described glass tube, and the two ends of dialysis tubing are stretched out and turn up from two grounds of glass tube respectively, and the dialysis tubing end that is exposed to ground outside of turning up is tied up and is fixed on ground by rubber bar; Two grounds tying up behind dialysis tubing end are plugged with respectively a rubber plug, the rubber plug that is positioned at described glass tube right side is provided with digestive juice flexible pipe, the middle part of described digestive juice flexible pipe is provided with retaining valve, and the end of digestive juice flexible pipe is provided with rapid-acting coupling, and described rapid-acting coupling is described digestive juice input port.
CN201410289798.6A 2014-06-26 2014-06-26 Bionic digestion device for gastrointestinal tracts Active CN104020264B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105842407A (en) * 2016-06-16 2016-08-10 湖南中本智能科技发展有限公司 Vertical type animal gastrointestinal bionic digester
CN105974066A (en) * 2016-06-16 2016-09-28 湖南中本智能科技发展有限公司 Vertical type animal gastrointestinal tract bionic digestion device

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CN203124020U (en) * 2013-04-07 2013-08-14 王信娥 Test tube clamp for teaching
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CN103639004A (en) * 2013-12-02 2014-03-19 臧建南 Multi-hole-site test tube clamp
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CN101246650A (en) * 2008-02-22 2008-08-20 中国农业科学院北京畜牧兽医研究所 Broiler external digestion simulating device
CN101482460A (en) * 2009-02-18 2009-07-15 中国农业科学院北京畜牧兽医研究所 Monogastric animal bionic digestion system and method for simulating monogastric animal digestion based on the system
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105842407A (en) * 2016-06-16 2016-08-10 湖南中本智能科技发展有限公司 Vertical type animal gastrointestinal bionic digester
CN105974066A (en) * 2016-06-16 2016-09-28 湖南中本智能科技发展有限公司 Vertical type animal gastrointestinal tract bionic digestion device

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