CN104000629A - Ventricular septal defect occluder - Google Patents
Ventricular septal defect occluder Download PDFInfo
- Publication number
- CN104000629A CN104000629A CN201410225299.0A CN201410225299A CN104000629A CN 104000629 A CN104000629 A CN 104000629A CN 201410225299 A CN201410225299 A CN 201410225299A CN 104000629 A CN104000629 A CN 104000629A
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- CN
- China
- Prior art keywords
- stopper
- thin film
- panel
- millimeters
- district
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00592—Elastic or resilient implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00606—Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
- A61B2017/00654—Type of implements entirely comprised between the two sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
Abstract
The invention provides a ventricular septal defect occluder. A fabric body comprises a left-side disc region, a middle cylindrical region and a right-side eccentric disc region; the fabric body extends outwards by 1.5-2mm to form the edge of the left-side disc region; the diameter of the middle cylindrical region is between 4mm and 20mm, and the thickness of the middle cylindrical region is between 3mm and 4mm; the right-side eccentric disc region is arranged eccentrically, relative to the left-side disc region, and the shortest edge of the right-side disc region extends outwards by 0.5mm from the outer diameter of the middle cylindrical region, while the longest edge of the right-side disc region extends outwards by 3.5mm; the closed-up positions of the fabric body are located in the centers of the left-side disc region and the right-side eccentric disc region, respectively, and a thin film is arranged in the internal cavity of the middle cylindrical region. The eccentric structure of the occluder is arranged reasonably, and therefore, the occluder is capable of meeting the requirement on clamping a defect opening and also relieving the problem of ventricular septal compression conduction block caused by too long trailing; the basic function of clamping can be realized, and meanwhile, resistance to blood is reduced as much as possible when the flood flows through, and as a result, the blood is enabled to flow smoothly.
Description
Technical field
This invention relates to the stopper field using in the damaged shutoff prosthesis of interventricular septum, specifically the damaged stopper of a kind of interventricular septum.
Background technology
Interventricular septum, at asyntaxia, forms abnormal traffic, produces left to right shunt in ventricle level, and it can exist separately, also the ingredient of certain Complex Congenital Heart Diseases.It is one of modal congenital heart disease that chamber lacks.
In interventricular septum damage revamping art, usually use symmetric form stopper and asymmetric stopper to carry out shutoff operation at present.Some damaged part is positioned at the upper end of interventricular septum, and near aortic valve or cusps of pulmonary valve, its left ventricle one side is aortic valvular ring, and right ventricle side is valve of pulmonary trunk ring, and does not have corresponding muscular tissue to support.The structure of current asymmetric stopper as shown in Figure 9, right side is complete eccentric structure, and upper end and waist cylinder maintain an equal level completely, although this structure can avoid valve of pulmonary trunk ring to impact, the stopper of this structure in use, has the risk coming off.Because the eccentric structure design of existing eccentric structure downside is reasonable not, the length of afterbody is in 5.5 millimeter simultaneously, and in the process using, oversize afterbody can be oppressed interventricular septum, causes conduction block, brings adverse influence.
The inventor analyzes discovery in conjunction with long-term clinical experience, the fluctuation pressure of left ventricle is obviously greater than the fluctuation pressure of right ventricle, make stopper in both sides repeatedly stressed with remove the alternation procedure of power, in this course, both are due to the discontinuity of two ends up and down on right side, stopper can deflect, and causes displacement even to come off.Simultaneously, because the fluctuation pressure of left ventricle is greater than the fluctuation pressure of right ventricle, the projection card in described left side must retain, eccentric card for right side need to be improved its structure, regard to the compressing of interventricular septum to improve eccentric disc, be conducive to improve the risk that stopper comes off under ventricle dynamic action simultaneously.
Therefore, the inventor thinks that existing stopper all can not meet the needs of the shutoff prosthesis of these privileged sites, has the space of further improvement and optimization.
Summary of the invention
In order to solve the deficiencies in the prior art, the invention provides the damaged stopper of a kind of interventricular septum, for the damaged shutoff near valve of pulmonary trunk ring place of interventricular septum, a kind of for the damaged special stopper of aortic valve ad-hoc location, solve existing shutoff place and interventricular septum is oppressed to the problem that causes conduction block, solve stopper simultaneously and hold after surgery caducous problem.
The technical solution adopted for the present invention to solve the technical problems is:
The damaged stopper of a kind of interventricular septum, comprises knitted body and thin film, and described knitted body is mainly one-time formed through braiding and setting process with thin tinsel, and described thin film is medical macromolecule membrane, it is characterized in that,
Knitted body comprises left circles panel, middle circle tubular district and off-centre operation panel, right side,
And the size aspect in described left circles panel should meet, stretch out from the outer in middle circle tubular district 1.5 millimeters to 2 millimeters and form the edge in described left circles panel;
Middle circle tubular district, cylindric for the hollow of diameter between 4 millimeters to 20 millimeters, and and the disk district of both sides between seamlessly transit and continued presence, on thickness direction, the thickness in described middle circle tubular district is between 3 millimeters to 4 millimeters;
Off-centre operation panel, right side, off-centre operation panel, described right side is with respect to left circles panel eccentric setting, and minor face stretches out 0.5 millimeter from the outer radius in middle circle tubular district, and longest edge stretches out 3.5 millimeters from the outer radius in cylindric district;
Closing in place of described knitted body lays respectively at described left circles panel and off-centre operation panel, right side centre, and fixes a threaded threaded post of tool in described left circles panel closing in place by the mode of extrusion modling or welding fabrication;
The thin film that twice are launched is at least set in described middle circle tubular district internal cavities, and the surrounding of each thin film and knitted body are sewed up and are connected to form one.
Further, described thin film is high-molecular polyvinyl alcohol thin film or macromolecule silica gel thin film conventional in medical treatment.
Further, the closing in being positioned on described left circles panel caves inward, and described threaded post is arranged on
In depression.
Further, described thin film should launch fully, flatten, and does not allow to occur the phenomenon of stack, fold.
Further, described threaded post is the alloy body identical with knitted body material, and described threaded post is trapped in the inside of whole stopper in being, with ensure outer surface be one level and smooth, reduce thrombotic probability.
Further, the tinsel that described knitted body uses will have the alloy threadlet of memory function for nitinol or other.
The invention has the beneficial effects as follows:
The minor face in off-centre operation panel, right side stretches out 0.5 millimeter from the outer radius in cylindric district, and longest edge stretches out 3.5 millimeters from the outer radius in cylindric district; Eccentric structure arranges rationally, can either meet the requirement of blocking damaged mouthful, can alleviate again the interventricular septum compressing causing because hangover is oversize and conduct the problem of being obstructed, can realize the basic function of blocking, have simultaneously reduced for blood flow as far as possible out-of-date, the resistance causing for blood, makes blood flow smooth and easy.
Brief description of the drawings
Fig. 1 is the entity profile of the knitted body of invention stopper.
Fig. 2 is the side view of Fig. 1.
Fig. 3 be Fig. 1 partly cut open cutaway view.
Fig. 4 is the entity profile diagram with the stopper of membrane structure.
Fig. 5 is the weave effect schematic diagram of knitted body.
Fig. 6 is the expanded view of knitted body.
Fig. 7 is one of this stopper shutoff situation schematic diagram in operation.
Fig. 8 is two of the shutoff situation schematic diagram of this stopper in operation.
Fig. 9 is the structural representation of the asymmetric stopper commonly used.
In figure: 1 stopper, 11 left circles panels, 12 middle circle tubular districts, 13 off-centre operation panels, right side, 14 threaded post, 2 interventricular septum, 31 the first film sheets, 32 second diaphragms, 4 sew up, 5 closing-in structures.
Detailed description of the invention
As shown in Figures 1 to 8,
The present invention relates to the damaged stopper of a kind of interventricular septum, this stopper is made up of filament, impermeable thin film and retaining element.
For existing defect, the protection main body of this patent is as follows:
What develop is a kind of medical element that carries out shutoff for the interventricular septum breakage that approaches valve of pulmonary trunk position.This element makes shutoff process be full of flexibility by the damage of minimum level and the interventional method of minimum level, on this component structure, more meet the physiological structure of analysing of valve, and wound is down to bottom line, and make the position, accurate arrival closure part that this element can be complete, implement shutoff.
Its basic principle is, stopper 1 compressed and import to the damage location that needs the interventricular septum of shutoff 2 by conduit, then stopper being derived in conduit, because stopper has shape memory function, can restore to the original state, and both sides are stuck in the both sides of the breakage of interventricular septum 2, and disk district is positioned at left ventricle one side, and eccentric disc district is positioned at right ventricle one side, block and be fixed on breakage, finally conduit and seal wire are extracted out, complete fixing, as shown in Figure 7,8.
Based on above-mentioned description, this stopper is under hard-wired situation, make stopper can realize as much as possible the shutoff of defect, and make the flank of both sides be fitted in as much as possible tram, make the risk that stopper comes off that reduces of particularly trying one's best in cardiac pulse process.
Stopper provided by the invention is a kind of stopper of the ventricular septal defect that is specifically designed to treatment privileged sites simultaneously, is applicable to guide by conduit the stopper that manipulates operation.
Owing to wanting the position of shutoff near Aortopulmonary lobe, and special shape and position have determined the requirement of this stopper.
The main body of this stopper mainly with thin tinsel through weaving molding, formed by 72 one metal wire braidings, a knitted body, the structural style (as Fig. 1) that can adopt two ends to close up, and the entirety forming by special setting process.Here, above-mentioned tinsel, preferentially selects, and for example nitinol or other are made the alloy material with memory function, have both had certain flexibility, can, under the situation that removes external force, automatically return to original state again.For meeting the requirement of being with operation, should there is sufficient flexibility.The alloy using due to this stopper has memory function, stopper in importing process in compression state, and import smoothly, discharge reaching behind precalculated position, after release, can be returned to timely predetermined shape.
From structure, the knitted body part of this stopper comprises left circles panel 11, middle circle tubular district 12 and off-centre operation panel, right side 13, left circles extent sizes aspect should meet, stretch out from the outer of cylindrical region 2 millimeters (L), referenced in schematic 2.
Middle circle tubular district 12 is the cylindric of the hollow of diameter between 4 millimeters to 20 millimeters (I), and and the disk district of both sides and eccentric disc seamlessly transit and continued presence between going, can not occur sharp-pointed or there is discrete point, the size in this middle circle tubular district 12, can be made into a series, the breakage size of shutoff is selected as required, in strength character, this region has supports the own clamping force that damaged interventricular septum shrinks, and shape remains unchanged for a long period of time, described herein referring to for a long time taking year at age of people as unit, for example patient is 40 years old, product at least will meet the projected life of 30 years.On thickness direction, the thickness H in this cylindric district 12 is between 3 millimeters to 4 millimeters, and make one serial, substantially can meet the dimensional requirement at aortic valve place, especially, should ensure this thickness should be substantially and the thickness of aortic valve breakage adapt, avoid occurring that card is not tightly or too tight phenomenon.
Off-centre operation panel, right side 13, this off-centre operation panel, right side is the flat shape of a circle, and diameter dimension is identical with left circles panel, and minor face stretches out 0.5 millimeter (N) from the outer radius in cylindric district, longest edge is from the outer radius in cylindric district stretch out 3.5 millimeters (M).Three above-mentioned parts form by a setting process, are the netted of braiding in structure, and do not have discontinuous or sharp-pointed or uneven shape, should be and seamlessly transit.
Be that centre is closing in place in left circles panel, and the shape shape of a depression is done in this closing in place, and fix a threaded post 14 with helicitic texture at this recess by the formation of extrusion modling or welding, structure is similar with existing threaded post, and best, and this threaded post 14 is trapped in the inside of whole stopper in being, with ensure outer surface be one level and smooth, more level and smooth in appearance, meanwhile, reduce thrombotic probability.
Using in the process of metal wire knitted knitted body, according to the selection schemer difference of technique, conventionally can form the pattern closing up in one end; The pattern that also can adopt two ends to close up, pattern as shown in Figure 1, is another closing-in structure 5 of a knitted body in the center in off-centre operation panel, described right side.In theory, the processing technology of two closing-in structures is more simple than single bottling technique.The knitted body of these two kinds of versions is all within protection scope of the present invention.
Then use and there is impermeable sheet film and block, concrete preparation two each and every one the size circular diaphragm suitable with cylindric district area, be labeled as the first film sheet 31 and the second diaphragm 32, this diaphragm adopts macromolecular material to be made, for example, conventional high-molecular polyvinyl alcohol thin film or macromolecule silica gel thin film material in medical treatment.This diaphragm is embedded in the cavity in cylindric district, and launch fully, flatten, do not allow to occur the phenomenon of stack, fold, then use sewing process that the surrounding of thin film and cylindric district are sewed up to 4, form a partition-type structures, this sewing process should ensure that the node of suture is as much as possible little, level and smooth.
By above-mentioned mode, form a stopper.
This stopper, knitted body forms a flexible skeleton with certain memory function, and thin film is the barrier film of occlude blood.And the given shape of knitted body meets the shutoff needs of interventricular septum specific part.
Embodiment recited above is described the preferred embodiment of the present invention; not scope of the present invention is limited; design under the prerequisite of spirit not departing from the present invention; relevant technical staff in the field, to various distortion of the present invention and improvement, all should expand in protection domain as determined in the claims in the present invention book.
Claims (6)
1. the damaged stopper of interventricular septum, comprises knitted body and thin film, and described knitted body is mainly one-time formed through braiding and setting process with thin tinsel, and described thin film is medical macromolecule membrane, it is characterized in that,
Knitted body comprises left circles panel, middle circle tubular district and off-centre operation panel, right side,
And the size aspect in described left circles panel should meet, stretch out from the outer in middle circle tubular district 1.5 millimeters to 2 millimeters and form the edge in described left circles panel;
Middle circle tubular district, cylindric for the hollow of diameter between 4 millimeters to 20 millimeters, and and the disk district of both sides between seamlessly transit and continued presence, on thickness direction, the thickness in described middle circle tubular district is between 3 millimeters to 4 millimeters;
Off-centre operation panel, right side, off-centre operation panel, described right side is with respect to left circles panel eccentric setting, and minor face stretches out 0.5 millimeter from the outer radius in middle circle tubular district, and longest edge stretches out 3.5 millimeters from the outer radius in cylindric district;
Closing in place of described knitted body lays respectively at described left circles panel and off-centre operation panel, right side centre, and fixes a threaded threaded post of tool in described left circles panel closing in place by the mode of extrusion modling or welding fabrication;
The thin film that twice are launched is at least set in described middle circle tubular district internal cavities, and the surrounding of each thin film and knitted body are sewed up and are connected to form one.
2. the damaged stopper of a kind of interventricular septum according to claim 1, is characterized in that, described thin film is high-molecular polyvinyl alcohol thin film or macromolecule silica gel thin film conventional in medical treatment.
3. the damaged stopper of a kind of interventricular septum according to claim 1, is characterized in that, the closing in being positioned on described left circles panel caves inward, and described threaded post is arranged in depression.
4. the damaged stopper of a kind of interventricular septum according to claim 1, is characterized in that, described thin film should launch fully, flatten, and does not allow to occur the phenomenon of stack, fold.
5. the damaged stopper of a kind of interventricular septum according to claim 1, is characterized in that, described threaded post is the alloy body identical with knitted body material, and described threaded post is trapped in the inside of whole stopper in being.
6. the damaged stopper of a kind of interventricular septum according to claim 1, is characterized in that, the tinsel that described knitted body uses will have the alloy threadlet of memory function for nitinol or other.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410225299.0A CN104000629A (en) | 2014-05-26 | 2014-05-26 | Ventricular septal defect occluder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410225299.0A CN104000629A (en) | 2014-05-26 | 2014-05-26 | Ventricular septal defect occluder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104000629A true CN104000629A (en) | 2014-08-27 |
Family
ID=51361733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410225299.0A Pending CN104000629A (en) | 2014-05-26 | 2014-05-26 | Ventricular septal defect occluder |
Country Status (1)
| Country | Link |
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| CN (1) | CN104000629A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173120A (en) * | 2014-09-11 | 2014-12-03 | 山东省立医院 | Postoperation perivalvular leakage plugging device |
| CN104173122A (en) * | 2014-09-11 | 2014-12-03 | 山东省立医院 | Plugging device suitable for postoperation perivalvular leakage |
| CN106845497A (en) * | 2017-01-12 | 2017-06-13 | 天津大学 | Maize in Earlier Stage image damage caused by a drought recognition methods based on multi-feature fusion |
| CN112022234A (en) * | 2019-05-17 | 2020-12-04 | 先健科技(深圳)有限公司 | Implantable device and preparation method thereof |
| CN113288243A (en) * | 2021-07-26 | 2021-08-24 | 中国医学科学院阜外医院 | Atrial septal defect plugging device |
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| EP1222897A2 (en) * | 2001-01-12 | 2002-07-17 | Microvena Corporation | Septal defect occluder |
| CN2780121Y (en) * | 2005-04-19 | 2006-05-17 | 解启莲 | Interventricular diaphragm peripheral defect sealing device |
| CN2897196Y (en) * | 2006-01-10 | 2007-05-09 | 中国人民解放军第二军医大学 | Double-disk thin interventricular septal defect stopper with left large and right small |
| CN101687088A (en) * | 2007-06-21 | 2010-03-31 | Aga医药有限公司 | The multi-layer braided structures of occluding vascular defects |
| CN202458498U (en) * | 2012-03-06 | 2012-10-03 | 张湘鲁 | Heart septal defect drug-coated plugging device |
| US20120271348A1 (en) * | 2011-04-21 | 2012-10-25 | Tekulve Kurt J | Self closing occulsion device with a twist |
| CN102895046A (en) * | 2012-09-17 | 2013-01-30 | 邢泉生 | Plugging device for a subconal or double-artery-valve subarterial ventricular septal defect |
| CN203001008U (en) * | 2012-06-23 | 2013-06-19 | 上海普实医疗器械科技有限公司 | Elliptical eccentric interventricular septal defect stopper |
| CN103179909A (en) * | 2010-09-06 | 2013-06-26 | 诺沃泰科医药股份有限公司 | Device for closing openings or cavities in blood vessels |
| CN203828992U (en) * | 2014-05-26 | 2014-09-17 | 山东省立医院 | Interventricular septum damage plugging device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1222897A2 (en) * | 2001-01-12 | 2002-07-17 | Microvena Corporation | Septal defect occluder |
| CN2780121Y (en) * | 2005-04-19 | 2006-05-17 | 解启莲 | Interventricular diaphragm peripheral defect sealing device |
| CN2897196Y (en) * | 2006-01-10 | 2007-05-09 | 中国人民解放军第二军医大学 | Double-disk thin interventricular septal defect stopper with left large and right small |
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| CN202458498U (en) * | 2012-03-06 | 2012-10-03 | 张湘鲁 | Heart septal defect drug-coated plugging device |
| CN203001008U (en) * | 2012-06-23 | 2013-06-19 | 上海普实医疗器械科技有限公司 | Elliptical eccentric interventricular septal defect stopper |
| CN102895046A (en) * | 2012-09-17 | 2013-01-30 | 邢泉生 | Plugging device for a subconal or double-artery-valve subarterial ventricular septal defect |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173120A (en) * | 2014-09-11 | 2014-12-03 | 山东省立医院 | Postoperation perivalvular leakage plugging device |
| CN104173122A (en) * | 2014-09-11 | 2014-12-03 | 山东省立医院 | Plugging device suitable for postoperation perivalvular leakage |
| CN106845497A (en) * | 2017-01-12 | 2017-06-13 | 天津大学 | Maize in Earlier Stage image damage caused by a drought recognition methods based on multi-feature fusion |
| CN112022234A (en) * | 2019-05-17 | 2020-12-04 | 先健科技(深圳)有限公司 | Implantable device and preparation method thereof |
| CN113288243A (en) * | 2021-07-26 | 2021-08-24 | 中国医学科学院阜外医院 | Atrial septal defect plugging device |
| CN113288243B (en) * | 2021-07-26 | 2021-10-01 | 中国医学科学院阜外医院 | Atrial septal defect plugging device |
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