CN103990101A - Traditional Chinese medicine composition for treating gynecological disease - Google Patents
Traditional Chinese medicine composition for treating gynecological disease Download PDFInfo
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- CN103990101A CN103990101A CN201410265858.0A CN201410265858A CN103990101A CN 103990101 A CN103990101 A CN 103990101A CN 201410265858 A CN201410265858 A CN 201410265858A CN 103990101 A CN103990101 A CN 103990101A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating a gynecological disease. The traditional Chinese medicine composition comprises tibet inula root, dried ginger, terminaliachebuia, gypsum rubrum, rhubarb, caragana, bezoar, tibetan madder, wolfberry, cinnamon, turmeric, orange peel, Chinese yam, radix angelicae dahuricae and polygonatum kingianum. The traditional Chinese medicine composition has the effects of regulating menstruation to stop pain, removing stasis, promoting circulation of blood, restoring menstrual flow and expediting child delivery, and is used for treating amenorrhea, postpartum bleeding stomach ache, vexation and blood-insufficiency and the like.
Description
Technical field
The present invention relates to and belongs to the field of Chinese medicines, concrete and a kind of Chinese medicine composition for the treatment of gynaecopathia.
Background technology
Gynecological's blood stasis disease is multiple is born in 25-54 year, indivedual patients are less than 25 years old, absolutely large number patients be distributed in 25-34 year, 35-44 year account for 82% between these two age group, known in the majority with middle-young patients, clinical main manifestations is menorrhagia or amenorrhea, leak down, through more than dim, the primary symptom such as lower abdomen pain and soreness of waist Chu, rectal tenesmus etc.The medicament categories of state internal therapy gynecological blood stasis disease is various at present, the side effect of taking antibiotics treatment gynaecopathia is larger, may cause superinfection, safety is poor, in treatment stomachache and dysmenorrhea than the advantage of chemical medicine analgesic: chemical medicine analgesic is only interim pain relieving, and long-term taking toxic and side effects is obvious, existing Chinese medicine prescription is more, complicated process of preparation, but mostly therapeutic effect is not good, thoroughly radical curing of disease.Menoxenia be menstruation cycle, through amount and persistent period, there is one group of gynopathic general name of abnormal change.Wherein clinical comparatively common Hypomenorrhea or amenorrhea and irregular menstrual period, follow the symptoms such as dysmenorrhea simultaneously.
At present a lot of for the Chinese medicine of gynecological's menoxenia and dysmenorrhea, as TONGJING WAN, dysmenorrhea liquid, YUEYUESHU CHONGJI etc., they have the effect of blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, have the effect of the menoxenia for the treatment of gynecological, dysmenorrhea, but all not too people's satisfaction of their therapeutic effect.Therefore, a kind of therapeutic effect better healing of market demand medicine, selects for patient provides more treatment.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of gynaecopathia, this Chinese medicine composition active ingredient is high, evident in efficacy, there is the effect that regulating menstruation relieved the pain, changed silt promoting the circulation of blood, stimulates the menstrual flow and hasten parturition, be applicable to clinical treatment gynecological blood stasis disease, as menoxenia, amenorrhea, the puerperal disease such as congestion abdomen pain, vexed blood deficiency.
For realizing object of the present invention, provide following embodiment.
In one embodiment; treat a Chinese medicine composition for gynaecopathia, by the raw material of Chinese medicine of following weight portion, formed: Radix Inulae 23-27 part, Rhizoma Zingiberis 13-17 part,, Fructus Chebulae 18-22 part,, Mirabilitum crystallina 13-17 part,, Radix Et Rhizoma Rhei 8-12 part,, caragana 13-17 part,, Calculus Bovis 13-17 part,, ZANGQIANCAO 13-17 part,, Fructus Lycii 8-12 part,, Cortex Cinnamomi 8-12 part,, Rhizoma Curcumae Longae 8-12 part,, Pericarpium Citri tangerinae 18-22 part,, Rhizoma Dioscoreae 18-22 part,, Radix Angelicae Dahuricae 13-17 part and Rhizoma Polygonati 18-22 part.
In the above-described embodiment; preferably; Chinese medicine composition of the present invention, is comprised of the raw material of Chinese medicine of following weight portion: 25 parts of Radix Inulae,, 15 parts of Rhizoma Zingiberiss,, 20 parts of Fructus Chebulae,, 15 parts of Mirabilitum crystallinas,, 10 parts of Radix Et Rhizoma Rhei,, 15 parts of caraganas,, 15 parts of Calculus Boviss,, 15 parts of ZANGQIANCAO,, 10 parts of Fructus Lyciis,, 10 parts of Cortex Cinnamomis,, 10 parts, Rhizoma Curcumae Longae,, 20 parts of Pericarpium Citri tangerinaes,, 20 parts of Rhizoma Dioscoreaes,, 20 parts of 15 parts of the Radixs Angelicae Dahuricae, g and Rhizoma Polygonatis.
In one embodiment; treat a Chinese medicine composition for gynaecopathia, by the raw material of Chinese medicine of following weight, formed: Radix Inulae 23-27g, Rhizoma Zingiberis 13-17g, Fructus Chebulae 18-22g, Mirabilitum crystallina 13-17g, Radix Et Rhizoma Rhei 8-12g, caragana 13-17g, Calculus Bovis 13-17g, ZANGQIANCAO 13-17g, Fructus Lycii 8-12g, Cortex Cinnamomi 8-12g, Rhizoma Curcumae Longae 8-12g, Pericarpium Citri tangerinae 18-22g, Rhizoma Dioscoreae 18-22g, Radix Angelicae Dahuricae 13-17g and Rhizoma Polygonati 18-22g.
In above-mentioned specific embodiments; preferably; Chinese medicine composition of the present invention, is comprised of the raw material of Chinese medicine of following weight: Radix Inulae 25g, Rhizoma Zingiberis 15g, Fructus Chebulae 20g, Mirabilitum crystallina 15g, Radix Et Rhizoma Rhei 10g, caragana 15g, Calculus Bovis 15g, ZANGQIANCAO 15g, Fructus Lycii 10g, Cortex Cinnamomi 10g, Rhizoma Curcumae Longae 10g, Pericarpium Citri tangerinae 20g, Rhizoma Dioscoreae 20g, Radix Angelicae Dahuricae 15g and Rhizoma Polygonati 20g.
The Chinese medicine composition of the invention described above, its dosage form is tablet, capsule, powder, granule or watered pill, preferred formulation form is watered pill
In another embodiment, provide a kind of method of preparing Chinese medicine composition of the present invention, described compositions is watered pill, and the method comprises the following steps:
1) all Chinese crude drugs are smashed respectively, then pulverized, cross 100-120 mesh sieve, obtain fine powder;
2, the fine powder mix homogeneously of each medical material, adds suitable quantity of water, the general one-tenth watered pill.
Another object of the present invention, provides the purposes of traditional Chinese medicine composition for treating gynaecopathia of the present invention, i.e. the utilization of Chinese medicine composition of the present invention in preparation treatment medicine for gynecopathy, described gynaecopathia be amenorrhea, puerperal congestion abdomen pain, vexed blood deficiency.
Chinese medicine composition of the present invention and preparation thereof, have invigorate blood circulation, effect that blood stasis dispelling, Xiao Disorder, regulating menstruation relieve the pain, stimulate the menstrual flow and hasten parturition.Treatment for married woman Su You Disorder piece or blood stasis amenorrhea, menalgia, prolonged lochia, amenorrhea, puerperal congestion abdomen pain, vexed blood deficiency, safety is good, without obviously poison is secondary, can long-term taking, in treatment stomachache and dysmenorrhea, than chemical medicine analgesic, have a clear superiority in: chemical medicine analgesic is only interim pain relieving, and long-term taking toxic and side effects is obvious.Treated effect reaches more than 95%.
Chinese medicine composition of the present invention and preparation thereof, an oral 1-2g, preferred 1.2g, 1 time on the one.
The specific embodiment
Following examples are used for further describing for example and understanding essence of the present invention, rather than limit the scope of the invention by any way.
Embodiment 1
The Chinese medicine composition for the treatment of gynaecopathia: the raw material of Chinese medicine by following weight forms: Radix Inulae 25g, Rhizoma Zingiberis 15g, Fructus Chebulae 20g, Mirabilitum crystallina 15g, Radix Et Rhizoma Rhei 10g, caragana 15g, Calculus Bovis 15g, ZANGQIANCAO 15g, Fructus Lycii 10g, Cortex Cinnamomi 10g, Rhizoma Curcumae Longae 10g, Pericarpium Citri tangerinae 20g, Rhizoma Dioscoreae 20g, Radix Angelicae Dahuricae 15g and Rhizoma Polygonati 20g.
Preparation technology: above-mentioned raw material of Chinese medicine is smashed separately, pulverized, mix homogeneously, crosses 120 mesh sieves, and the powder of acquisition adds the general one-tenth pill of appropriate water, obtains the watered pill.This product is yellow ancestor's color watered pill, puckery.
Maybe by the agent of powder granulation, the powder of acquisition or incapsulate.
Embodiment 2
The Chinese medicine composition for the treatment of gynaecopathia: the raw material of Chinese medicine by following weight forms: Radix Inulae 25g, Rhizoma Zingiberis 15g, Fructus Chebulae 20g, Mirabilitum crystallina 15g, Radix Et Rhizoma Rhei 10g, caragana 15g, Calculus Bovis 15g, ZANGQIANCAO 15g, Fructus Lycii 10g, Cortex Cinnamomi 10g, Rhizoma Curcumae Longae 10g, Pericarpium Citri tangerinae 20g, Rhizoma Dioscoreae 20g, Radix Angelicae Dahuricae 15g and Rhizoma Polygonati 20g.
Preparation technology: above-mentioned raw material of Chinese medicine is smashed separately, pulverized, mix homogeneously, crosses 120 mesh sieves, and the powder of acquisition adds the general one-tenth pill of appropriate water, obtains the watered pill.
Maybe by the agent of powder granulation, the powder of acquisition or incapsulate.
Embodiment 3
The Chinese medicine composition for the treatment of gynaecopathia, is comprised of the raw material of Chinese medicine of following weight: Radix Inulae 23g, Rhizoma Zingiberis 17g, Fructus Chebulae 18g, Mirabilitum crystallina 13g, Radix Et Rhizoma Rhei 12g, caragana 13g, Calculus Bovis 17g, ZANGQIANCAO 17g, Fructus Lycii 12g, Cortex Cinnamomi 8g, Rhizoma Curcumae Longae 12g, Pericarpium Citri tangerinae 22g, Rhizoma Dioscoreae 22g, Radix Angelicae Dahuricae 17g and Rhizoma Polygonati 22g.
Preparation technology: above-mentioned raw material of Chinese medicine is smashed separately, pulverized, mix homogeneously, crosses 120 mesh sieves, and the powder of acquisition adds the general one-tenth pill of appropriate water, obtains the watered pill.
Maybe by the agent of powder granulation, the powder of acquisition or incapsulate.
Embodiment 4
The Chinese medicine composition for the treatment of gynaecopathia, is comprised of the raw material of Chinese medicine of following weight: Radix Inulae 27g, Rhizoma Zingiberis 13g, Fructus Chebulae 22g, Mirabilitum crystallina 17g, Radix Et Rhizoma Rhei 8g, caragana 17g, Calculus Bovis 13g, ZANGQIANCAO 13g, Fructus Lycii 8g, Cortex Cinnamomi 12g, Rhizoma Curcumae Longae 8g, Pericarpium Citri tangerinae 18g, Rhizoma Dioscoreae 18g, Radix Angelicae Dahuricae 13g and Rhizoma Polygonati 18g.
Preparation technology: above-mentioned raw material of Chinese medicine is smashed separately, pulverized, mix homogeneously, crosses 120 mesh sieves, and the powder of acquisition adds the general one-tenth pill of appropriate water, obtains the watered pill.
Maybe by the agent of powder granulation, the powder of acquisition or incapsulate.
Embodiment 5
The Chinese medicine composition for the treatment of gynaecopathia, is comprised of the raw material of Chinese medicine of following weight portion: 25 parts of Radix Inulae,, 15 parts of Rhizoma Zingiberiss,, 20 parts of Fructus Chebulae,, 15 parts of Mirabilitum crystallinas,, 10 parts of Radix Et Rhizoma Rhei,, 15 parts of caraganas,, 15 parts of Calculus Boviss,, 15 parts of ZANGQIANCAO,, 10 parts of Fructus Lyciis,, 10 parts of Cortex Cinnamomis,, 10 parts, Rhizoma Curcumae Longae,, 20 parts of Pericarpium Citri tangerinaes,, 20 parts of Rhizoma Dioscoreaes,, 20 parts of 15 parts of the Radixs Angelicae Dahuricae, g and Rhizoma Polygonatis.
Preparation technology: above-mentioned raw material of Chinese medicine is smashed separately, pulverized, mix homogeneously, crosses 120 mesh sieves, and the powder of acquisition adds the general one-tenth pill of appropriate water, obtains the watered pill.
Maybe by the agent of powder granulation, the powder of acquisition or incapsulate.
Clinical trial result:
The present invention treats the clinical efficacy of gynaecopathia
1.1 case selections: to treat the diseases such as menoxenia, dysmenorrhea, puerperal congestion abdomen pain, leucorrhea abnormal, functional endometritis, amenorrhea, there is the wherein patient of any 2-3 item of symptom symptom all to can be used as experimenter, enter altogether group 80 routine patients, average sick time 6 years, there are 5 examples only ill 1 year, the longest case history 15 years.Experimenter is equally divided into 4 groups, and every group of 20 examples are given respectively the watered pill and the BAIXIAO DAN Pai Xiao Disorder ball of embodiment 2-4.
1.2 medicament selection and instructions of taking:
Administration group: the watered pill that embodiment 2-4 obtains; Within 10 days, be a course for the treatment of, treat 3-5 the course for the treatment of.1.2g on the one, 1 time on the one.
Matched group: BAIXIAO DAN Pai Xiao Disorder ball, Shanghai Leiyun Pharmaceutical Industry Co., Ltd. produces.
1.3 efficacy assessment standard
Recovery from illness: clinical symptoms, sign disappear or substantially disappear;
Effective: clinical symptoms, sign are obviously improved;
Effective: clinical symptoms, sign are improved.
Invalid: sings and symptoms is without significant change.
1.4 result of the tests: after completing 3-5 the course for the treatment of, result is as follows: (unit: example)
2 groups of embodiment: effective 4 effective 4 invalid 0 cure rates 60.5% of clinical recovery 13, total effective rate 100%.
3 groups of embodiment: effective 5 effective 4 invalid 1 cure rates 50.0% of clinical recovery 10, total effective rate 95%.
4 groups of embodiment: effective 5 effective 2 invalid 1 cure rates 55.0% of clinical recovery 11, total effective rate 95%.
Matched group: effective 4 effective 3 invalid 5 cure rates 40.0% of clinical recovery 8, total effective rate 75%.
Through above-mentioned test, pain relief progressively disappearing after patient's medication, has rosy cheeks, passages through which vital energy circulates is normal, and patient feels well, and mental status is good.Cure rate reaches more than 50%, and total effective rate reaches more than 95%.Compare Yu Xiao Disorder ball, curative effect is better.
Claims (7)
1. treat a Chinese medicine composition for gynaecopathia, by the raw material of Chinese medicine of following weight portion, formed: Radix Inulae 23-27g, Rhizoma Zingiberis 13-17g, Fructus Chebulae 18-22g, Mirabilitum crystallina 13-17g, Radix Et Rhizoma Rhei 8-12g, caragana 13-17g, Calculus Bovis 13-17g, ZANGQIANCAO 13-17g, Fructus Lycii 8-12g, Cortex Cinnamomi 8-12g, Rhizoma Curcumae Longae 8-12g, Pericarpium Citri tangerinae 18-22g, Rhizoma Dioscoreae 18-22g, Radix Angelicae Dahuricae 13-17g and Rhizoma Polygonati 18-22g.
2. compositions as claimed in claim 1, is comprised of the raw material of Chinese medicine of following weight portion: Radix Inulae 25g, Rhizoma Zingiberis 15g, Fructus Chebulae 20g, Mirabilitum crystallina 15g, Radix Et Rhizoma Rhei 10g, caragana 15g, Calculus Bovis 15g, ZANGQIANCAO 15g, Fructus Lycii 10g, Cortex Cinnamomi 10g, Rhizoma Curcumae Longae 10g, Pericarpium Citri tangerinae 20g, Rhizoma Dioscoreae 20g, Radix Angelicae Dahuricae 15g and Rhizoma Polygonati 20g.
3. compositions as claimed in claim 1 or 2, its dosage form is tablet, capsule, powder, granule or watered pill.
4. compositions as claimed in claim 3, its dosage form is watered pill.
5. a method of preparing the Chinese medicine composition of claim 4, described compositions is watered pill, the method comprises the following steps:
1) all Chinese crude drugs are smashed respectively, then pulverized, cross 100-120 mesh sieve, obtain fine powder;
2) the fine powder mix homogeneously of each medical material, adds suitable quantity of water, the general one-tenth watered pill.
6. the utilization of the Chinese medicine composition of claim 1 in preparation treatment medicine for gynecopathy.
7. utilization as claimed in claim 6, described gynaecopathia be amenorrhea, puerperal congestion abdomen pain, vexed blood deficiency.
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CN105749167A (en) * | 2016-04-12 | 2016-07-13 | 刘昌红 | Traditional Chinese medicine composition for treating amenorrhea |
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Application publication date: 20140820 |