CN103977078A - Traditional Chinese medicine preparation for treating human dysentery disease and production method thereof - Google Patents
Traditional Chinese medicine preparation for treating human dysentery disease and production method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating human dysentery disease and a production method thereof. The preparation is composed of the following medicinal raw materials in parts by weight: 10 to 15 parts of guava leaf, 10 to 15 parts of pine needle, 15 to 20 parts of myrtle leaf, 15 to 20 parts of sticktight, and 10 to 15 parts of purslane. The traditional Chinese medicine preparation has the functions of drying dampness, invigorating the spleen, clearing heat, removing toxicity, astringing to arrest diarrhea, tonifying deficiency, and stopping bleeding. The raw materials can be made into granules, capsules, tablets, oral liquid or tea bags through scientific compatibility. The preparation can effectively treat the human dysentery disease, and has the advantages of no drug resistance and no side or toxic effect due to the pure traditional Chinese herbal components.
Description
Technical field
The present invention relates to Chinese medicine preparation, particularly relate to a kind of Chinese medicine preparation and production method thereof of the people's for the treatment of dysentery.
Background technology
Dysentery, ancient title intestinal is warded off, dysentery.For one of acute infectious intestinal disease.Clinical taking heating, stomachache, tenesmus, stool containing pus and blood as cardinal symptom.If infect epidemic disease poison, sharply, companion is high heat suddenly in morbidity, and coma, convulsions person, be fulminant dysentery.Dysentery is from the beginning of, foreknowledge stomachache, dysentery then, day and night for several times to tens of times not etc.Be mainly in summer and autumn, by damp and hot heresy, disorder of the spleen and stomach caused by internal damage, causes dysfunction of the spleen in transportation, and stomach loses food stagnation removing, more holds under the arm stagnantly, ferments intestinal and forms.Now have on the market quite a lot of medicine of controlling dysentery, but these medicines are often taking antibiotic as main, as norfloxacin, gentamycin, berberine and bactrim etc.This type of antibiotic has certain therapeutic effect at the use initial stage, if life-time service can make human body produce drug resistance, and antibiotic also has side effect to a certain degree, is detrimental to health.The present invention can effectively overcome this deficiency, and pure Chinese medicine is made, and has no side effect, and has no drug resistance, safe and reliable.
Through retrieval, we have found about the open source literature of the Chinese medicine for the treatment of people dysentery as follows:
1, Chinese patent, application number: CN201210331815.9 title: a kind of Chinese medicine for the treatment of dysentery, open (bulletin) number: CN102813851A, application (patent right) people: Xin Rucai, invention (design) people: pungent as ability address: No. 5, Huayuan Road, Licheng District, Jinan City, ShanDong Province, summary: a kind of Chinese medicine for the treatment of dysentery.The Chinese medicine of this treatment dysentery is taking Herba Eleusines Indicae, Herba humuli scandentis, Flos Punicae Albescentis, Folium Viticis Negundo, Caulis Cucurbitae, Folium Psidii Guajavae, Radix Momordicae Charantiae, Rhizoma Coptidis, Fructus Evodiae, Fructus trachycarpi, Bulbus Allii Macrostemonis, Flos micheliae Albae, Cortex Pruni Salicinae Radicis, Herba Dianthi, Radix Luffae and Radix Sorghum vulgare Pers. as raw material, formulated according to certain weight proportion.
2, Chinese patent, application number: CN201010275186.3 title: a kind of Chinese medicine composition for the treatment of dysentery, open (bulletin) number: CN101947268A, application (patent right) people: Wang Fushan, invention (design) people: Wang Fushan address: No. 15, Dongxing street, white elephant town, north, Yueqing City of Zhejiang Province summary: a kind of Chinese medicine composition for the treatment of dysentery, it is made up of the raw material of following weight proportioning: fluxweed 13-17, Radix Pulsatillae 13-17, Herba Pteridis Multifidae 28-32, Rhizoma Coptidis 10-14, white red sorrel 13-17, Herb Polygoni Chinensis 28-32, Herba Portulacae 18-22, Cortex Phellodendri 10-14, Herba Acalyphae 10-14, dysentery grass 13-17, Cortex Fraxini 10-14, little grass 18-22.
Summary of the invention
The object of the invention is to provide to market a kind of Chinese medicine preparation of the treatment people dysentery that is different from existing formula, the present invention is according to science compatibility, can be made into oral liquid, granule, encapsulated, tablet or teabag.
To achieve these goals, technical scheme of the present invention is:
Treat a Chinese medicine preparation for people's dysentery, its medicine material and parts by weight are as follows:
Folium Psidii Guajavae 10-15 part;
Folium Pini 10-15 part;
Myrtillin folium 15-20 part;
Herba Bidentis Bipinnatae 15-20 part;
Herba Portulacae 10-15 part.
Production method comprises the steps:
Get in proportion above-mentioned Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae, the Herba Portulacae five tastes, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filters, filtrate merges, get sucrose and make in right amount syrup, merge with above-mentioned medicinal liquid, add antiseptic appropriate, leave standstill, filter, fill, obtains oral liquid.Using method: every day 2 times, each 5 grams, seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Get in proportion above-mentioned Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae, the Herba Portulacae five tastes, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to the clear paste that 55 ° of C relative densities are 1.15-1.20, add 90% ethanol make containing alcohol amount be 60%, room temperature leave standstill 12 hours, filter, reclaim ethanol, be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix, granulation agent or encapsulated, or make tablet.Using method: every day 2-3 time, each 2-3 gram.Seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Get in proportion above-mentioned Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae, the Herba Portulacae five tastes, after cleaning respectively, dry, pulverize with pulverizer, cross 50 mesh sieves, in proportion each ground product is merged, pack in ventilative Fibre Bag, weight per package 2-5 gram, makes teabag.Using method: every day 2 times, each 5 grams, each 10 grams of severe one, seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
The side of the each raw material of Chinese medicine of the present invention separates as follows:
Above-described Folium Psidii Guajavae, another name: chicken is vowed bar in tea, kind Folium Persicae, fiber crops, [Latin formal name used at school]
folium Psidii Guajavae Psidium guajava L..[nature and flavor] bitter in the mouth; Puckery; Property flat [function cures mainly] drying damp and strengthening spleen; Heat-clearing and toxic substances removing.Main dysentery stomachache; Dyspeptic abdominal distention; Gingivitis; Rheumatic arthralgia; Eczema ecthyma; Furuncle swelling toxin; Treating swelling and pain by traumatic injury; Traumatic hemorrhage; Snake bite and insect sting; " Nanning City's medicine will " is recorded: astringing to arrest diarrhea.Control and have loose bowels, chronic dysentery, eczema, wound hemorrhage.
Above-described Folium Pini [Latin formal name used at school]
pinus armandi Franch, be the leaf of Pinaceae pine genus plant, [function cures mainly] dispeiling pathogenic wind and removing dampness; Killing parasites for relieving itching; Blood-promoting and mind-easing.The main air flaccidity syndrome and arthralgia syndrome that wets; Foot gas; Eczema; Tinea; Rubella pruritus; Traumatic injury; Neurasthenia; Chronic nephritis; Hypertension.Preventing encephalitis, influenza.Each discussion: 1. " book on Chinese herbal medicine converges and says ": Folium Pini, curing rheumatism, treats the vertical medicine of tinea leprosy malignant boil also.Property dry matter profit, fry black kind curing rheumatism, stubborn dermatitis is wet rotten, dipping is dry, and deposited the eleventh month of the lunar calendar chilblain.Raw get to mash make ball, can control strong wind leprosy disease, or severe and migratory arthralgia pain, or beriberi flaccidity syndrome and arthralgia syndrome, or the card such as wind syndrome of head headache.More than number is sick, and it is suitable that all passes rheumatism causes patient, if forbid it because blood-deficiency and wind-dry causes patient.2. " Mingyi Bielu ": main air eczema, piliation, settling five organs.3. " Japan hanako materia medica ": chilblain, rheumatism skin ulcer.4. Compendium of Material Medica: go wind pain foot numbness, kill cadelle.5. " the SHENGCAO property of medicine is standby to be wanted ": kill hereby, solid carbon dioxide, antipruritic, bury mouthful (closing the open sore part), wash chancre, control hereby scabies.6. " can approximately cure mirror ": ward off pestilence gas.
7. Guangzhou army " conventional Chinese herbal medicine handbook ": control neurasthenia, Vitamin C lacks, trophedema; Prevent and treat epidemic encephalitis, influenza.
Above-described myrtillin folium is myrtaceous leaf.Fructus Rhodomyrti, another name: hilllock M.-dodecandrum, mountain M.-dodecandrum, Duo Lian, when Radix pyri, harvest that subtree, bean are harvested, secondary Buddhist nun, black belly, work as mud, [Latin formal name used at school]
rhodomyrtus tomentosa, be used as medicine with root, leaf and fruit.Uproot autumn, cleans, and section, dries.Fruit edible; Herb hyoscine, has promoting blood circulation to remove obstruction in the collateral, astringing to arrest diarrhea, effect of tonify deficiency hemostasis.Property sweet-puckery flavor flat, have nourish blood, effect of hemostasis, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs.Control blood deficiency, haematemesis, epistaxis, have blood in stool, dysentery, proctoptosis, tinnitus, seminal emission, metrorrhagia, be with inferior.Root: dispelling, collateral-activating, astringing to arrest diarrhea.For acute and chronic gastroenteritis, stomachache, dyspepsia, hepatitis, dysentery, rheumatic arthritis, lumbar muscle strain, dysfunctional uterine hemorrhage, proctoptosis; Burn and scald is controlled in external.Leaf: astringing to arrest diarrhea, hemostasis.For acute gastroenteritis, dyspepsia, dysentery: traumatic hemorrhage is controlled in external.Really: enrich blood, nourish, antiabortive.For anemia, body void after being ill, neurasthenia, tinnitus, seminal emission.
Above-described Herba Bidentis Bipinnatae, [Latin formal name used at school]
bidens pilosa L.another name: SANYE Bidens bipinnata, bidens pilosa, terrible Hemerocallis citrina Baroni, Shandong lao-ya-tsao, Herba Bidentis Bipinnatae, terrible spicule, for the conventional medical herbs of folks of china, there is effect of heat-clearing and toxic substances removing, removing blood stasis and activating blood flow, cure mainly upper respiratory tract infection, laryngopharynx swelling and pain, acute appendicitis, acute icterohepatitis, gastroenteritis, Fengshi Guanjie pain, malaria, furuncle, venom, treating swelling and pain by traumatic injury are controlled in external.Herb (Herba bidentis parviflorae): hardship, flat.Heat-clearing and toxic substances removing, promoting blood circulation by removing wind.For laryngopharynx swelling and pain, vomit and diarrhoea, dyspepsia, rheumatic arthritis, malaria, furuncle, venom, treating swelling and pain by traumatic injury.Each discussion: 1. treating malaria disease: 250～350 grams of fresh beggar-ticks.Decoct soup, add eggs boiled soup clothes (" east, Fujian book on Chinese herbal medicine ").2. control dysentery: one of the soft bud of Herba Bidentis Bipinnatae.Decocting soup, Hakuri is joined brown sugar, and red diarrhea is joined white sugar, serve on 3 times by (" Quanzhou book on Chinese herbal medicine ").
The above Herba Portulacae [Latin formal name used at school]
portulaca oleracea L., another name: horse Herba Amaranthi tricoloris, Wu Hangcao, long life dish, five Medulla Tetrapanacis, Semen Benincasae dish, rope made of hemp dish, Dens Equi dish, locust dish.Function cures mainly: heat-clearing and toxic substances removing, loose blood detumescence.Control hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, trace scrofula.For diarrhoea, dysentery due to damp and hot, often join Rhizoma Coptidis, the Radix Aucklandiae.Take orally or smash juice external application, controlling carbuncle.Also for having blood in stool, metrorrhagia, have anastalsis.Each discussion: (1) Shen in the Meng: exudative dermatitis is bald in vain, with Dens Equi cream and ash coating.Control dysentery and a wind cutting, apply flogging injury.(2) " Treatise on Dietetic Therapy ": bright door.Also control dysentery.(3) " Kaibao Bencao ": the blind white clouds of argument, sharp defecation, cold removing heat, kills parasites, quenches the thirst, broken crux carbuncle skin ulcer.Burn again for ash, and vinegar dregs for many years, first moxibustion fourth is swollen.To seal it, root goes out. and the raw strand juice clothes of smashing, when disliking thing under profit, remove tapeworm.(4) " the southern regions of the Yunnan Province book on Chinese herbal medicine ": QI invigorating, the heat of relieving summer heat, the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, intestine moistening, removing food stagnancy is stagnant, and parasite killing is treated skin ulcer congestion and swelling pain.(5) " the SHENGCAO property of medicine is standby to be wanted ": control red diarrhea disease, heat clearing away poison, washes hemorrhoid infantile malnutrition furuncle.
In the present invention, the pharmacological function of each composition is:
Folium Psidii Guajavae is drying damp and strengthening spleen, heat-clearing and toxic substances removing, astringing to arrest diarrhea;
Folium Pini dispeiling pathogenic wind and removing dampness, removing toxic substances, settling five organs;
Myrtillin folium promoting blood circulation to remove obstruction in the collateral, astringing to arrest diarrhea, tonify deficiency hemostasis;
Herba Bidentis Bipinnatae heat-clearing and toxic substances removing, removing blood stasis and activating blood flow;
Herba Portulacae heat-clearing and toxic substances removing, loose blood detumescence.
Beneficial effect of the present invention:
1, the present invention adopts Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae and Herba Portulacae five tastes Chinese herbal medicine to add in formula to prepare, utilize Chinese herbal medicine self effect to reach the object for the treatment of people dysentery, have no side effect, have no drug resistance, especially be applicable to needing life-time service, slowly the patient of conditioning.
2, production process of the present invention is simple, does not pollute; Using method is simple, is simple and easy to use, and raw material sources are wide, and price is low, alleviates people's financial burden.
Detailed description of the invention
Embodiment 1
Get 10 parts of above-mentioned Folium Psidii Guajavae, 10 parts, Folium Pini, 15 parts of myrtillin foliums, 15 parts of Herba Bidentis Bipinnatae, 10 parts of Herba Portulacaes, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filters, filtrate merges, get sucrose and make in right amount syrup, merge with above-mentioned medicinal liquid, add antiseptic appropriate, leave standstill, filter, fill, obtains oral liquid.Using method: every day 2 times, each 5 grams, seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Embodiment 2
Get 11 parts of above-mentioned Folium Psidii Guajavae, 11 parts, Folium Pini, 16.5 parts of myrtillin foliums, 16.5 parts of Herba Bidentis Bipinnatae, 11 parts of five tastes of Herba Portulacae, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to the clear paste that 55 ° of C relative densities are 1.15-1.20, add 90% ethanol make containing alcohol amount be 60%, room temperature leaves standstill 12 hours, filters, and reclaims ethanol, be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix, granulation agent.Using method: every day 2-3 time, each 2-3 gram.Seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Embodiment 3
Get 12.5 parts of above-mentioned Folium Psidii Guajavae, 12.5 parts, Folium Pini, 18 parts of myrtillin foliums, 18 parts of Herba Bidentis Bipinnatae, 12.5 parts of five tastes of Herba Portulacae, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filter, filtrate merges, 60-70 DEG C is evaporated to the clear paste that 55 ° of C relative densities are 1.15-1.20, add 90% ethanol make containing alcohol amount be 60%, room temperature leave standstill 12 hours, filter, reclaim ethanol, be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix, granulation, encapsulated one-tenth capsule.Using method: every day 2-3 time, each 2-3 gram.Seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Embodiment 4
Get 13.5 parts of above-mentioned Folium Psidii Guajavae, 13.5 parts, Folium Pini, 19 parts of myrtillin foliums, 19 parts of Herba Bidentis Bipinnatae, 13.5 parts of five tastes of Herba Portulacae, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filter, filtrate merges, and 60-70 DEG C is evaporated to the clear paste that 55 ° of C relative densities are 1.15-1.20, add 90% ethanol make containing alcohol amount be 60%, room temperature leaves standstill 12 hours, filters, and reclaims ethanol, be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix, make tablet.Using method: every day 2-3 time, each 2-3 gram.Seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Embodiment 5
Get 15 parts of above-mentioned Folium Psidii Guajavae, 15 parts, Folium Pini, 20 parts of myrtillin foliums, 20 parts of Herba Bidentis Bipinnatae, 15 parts of five tastes of Herba Portulacae, after cleaning respectively, dry, pulverize with pulverizer, cross 50 mesh sieves, in proportion each ground product is merged, pack in ventilative Fibre Bag, weight per package 2-5 gram, makes teabag.Using method: every day 2 times, each 5 grams, each 10 grams of severe one, seven days courses for the treatment of, can fully recover 1-2 the course for the treatment of.
Application Example:
Embodiment 1,
Liu, 30 years old, certain business event person, needed on business trips for a long time, suddenly heating stomachache in certain ways of going on business in 2013, have loose bowels more than, certainly take Western medicine and do not feel any better, introduce by friend, start to take the Chinese medicine oral liquid of the embodiment of the present invention 1, drink every day and take a turn for the better afterwards for twice, three day, he is very satisfied to effect.
Embodiment 2,
Tan, 28 years old, office's white collar.Due to job demand, Miss Tan can not have a meal every day on time, adds self taste and lays particular stress on, and likes eating peppery, and in July, 2013, the unexpected pain of her abdominal part in certain day evening, is and burns sample pain, has loose bowels a whole night more than ten time.Through examination in hospital, be diagnosed as dysentery.Take after Western medicine that hospital opens to such an extent that alleviate to a certain extent, but time have a recurrence.Do not think to have Western medicine again she, take afterwards upon somebody's introduction the Chinese medicine granules of the embodiment of the present invention 2, eat every day two to three times, after the week, fully recover.She is very satisfied to result of use.
Embodiment 3,
Zhang, 10 years old, in JIUYUE, 2013 Zhang had a high fever suddenly, and with symptoms such as nauseating, vomiting, stomachache, diarrhoea.Go to see a doctor, confirm as acute dysentery.After taking Western medicine that hospital opens, can only be eased, fail to fully recover always.Start afterwards to take after being introduced the capsule of the embodiment of the present invention 3, eat every day three times, eaten week recovery from illness.Successful.
Embodiment 4,
Sweet certain, 40 years old, top managers.Sweet certain often go out dinner party because of job demand, diet is irregular, there is epigastrium dull pain in January, 2014, vomiting, the symptom such as have blood in stool, do not feel any better from taking Western medicine a couple of days, after being introduced, start to take the Chinese medicinal tablet of the embodiment of the present invention 4, eat every day three times, after two weeks week, take a turn for the better gradually, he is very satisfied to effect.
Embodiment 5,
Beam, 20 years old, student, in May, 2014 Tiantu sense stomachache, and had the symptoms such as diarrhoea, tenesmus, evacuation of pus hemafecia.Have no improvement from taking Western medicine, start after being introduced to take the Chinese medicine tea bag of the embodiment of the present invention 5, steep check after twice, two week every day, be almost recovered.
Claims (4)
1. a Chinese medicine preparation for the treatment of people's dysentery, is characterized in that: its medicine material and parts by weight are as follows:
Folium Psidii Guajavae 10-15 part;
Folium Pini 10-15 part;
Myrtillin folium 15-20 part;
Herba Bidentis Bipinnatae 15-20 part;
Herba Portulacae 10-15 part.
2. the Chinese medicine preparation for the treatment of people dysentery according to claim 1, is characterized in that: get in proportion above-mentioned Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae, the Herba Portulacae five tastes, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filter, filtrate merges, and gets sucrose and makes in right amount syrup, merge with above-mentioned medicinal liquid, add antiseptic appropriate, leave standstill, filter, fill, obtains oral liquid.
3. the Chinese medicine preparation for the treatment of people dysentery according to claim 1, it is characterized in that: get in proportion above-mentioned Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae, the Herba Portulacae five tastes, per kilogram dose adds 5 kg of water and decocts two to three times, each 1 hour, filter, filtrate merges, 60-70 DEG C is evaporated to the clear paste that 55 ° of C relative densities are 1.15-1.20, add 90% ethanol make containing alcohol amount be 60%, room temperature leaves standstill 12 hours, filter, reclaim ethanol, be concentrated into the thick paste that relative density is 1.30-1.35, add appropriate amount of auxiliary materials, mix, granulation agent or encapsulated, or make tablet.
4. the Chinese medicine preparation for the treatment of people dysentery according to claim 1, it is characterized in that: get in proportion above-mentioned Folium Psidii Guajavae, Folium Pini, myrtillin folium, Herba Bidentis Bipinnatae, the Herba Portulacae five tastes, after cleaning respectively, dry, pulverize with pulverizer, cross 50 mesh sieves, in proportion each ground product is merged, pack in ventilative Fibre Bag, weight per package 2-5 gram, makes teabag.
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| CN105213483A (en) * | 2015-09-26 | 2016-01-06 | 梁佳灵 | The Chinese medicine preparation of control artificial breeding wild boar dysentery |
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| CN106138811A (en) * | 2016-07-27 | 2016-11-23 | 姚红亮 | Red dysentery characterized by white mucous stool decoction |
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| CN104306452A (en) * | 2014-10-29 | 2015-01-28 | 扶绥县科学技术情报研究所 | Chinese herba preparation for treating enterogastritis of macaques and production method thereof |
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