CN103948707B - A kind of Chinese medicine for the treatment of restless legs syndrome - Google Patents
A kind of Chinese medicine for the treatment of restless legs syndrome Download PDFInfo
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- CN103948707B CN103948707B CN201410225705.3A CN201410225705A CN103948707B CN 103948707 B CN103948707 B CN 103948707B CN 201410225705 A CN201410225705 A CN 201410225705A CN 103948707 B CN103948707 B CN 103948707B
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- 239000003814 drug Substances 0.000 title claims abstract description 31
- 208000005793 Restless legs syndrome Diseases 0.000 title claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 8
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 7
- 210000000582 semen Anatomy 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 8
- 229940126678 chinese medicines Drugs 0.000 abstract description 2
- 230000006872 improvement Effects 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract 1
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- 210000004369 blood Anatomy 0.000 description 10
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- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 210000002435 tendon Anatomy 0.000 description 4
- 208000005392 Spasm Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 210000003141 lower extremity Anatomy 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
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- 239000002671 adjuvant Substances 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- AAOVKJBEBIDNHE-UHFFFAOYSA-N diazepam Chemical compound N=1CC(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 AAOVKJBEBIDNHE-UHFFFAOYSA-N 0.000 description 1
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Abstract
The present invention relates to the field of Chinese medicines, a kind of Chinese medicine for the treatment of restless legs syndrome, it is made up of the component of following raw materials according medicine according to constant weight proportioning: the Radix Paeoniae Alba, Fructus Chaenomelis, Poria, Rhizoma Atractylodis Macrocephalae (parched), Radix Angelicae Sinensis, Radix Cyathulae, Semen Ziziphi Spinosae, Radix Bupleuri, Radix Glycyrrhizae.Chinese medicine of the present invention has good effect, and cure rate is high, and cost is low, and medicine source is wide, without any side effects, stable curative effect, not easily the advantage such as recurrence, to take medicine 10 days be one the course for the treatment of statistics, total effective rate 100%, cure rate 94.4%, improvement 5.6%.
Description
Technical field
the present invention relates to a kind of Chinese medicine for the treatment of restless legs syndrome, belong to technical field of Chinese medicines.
Background technology
restless legs syndrome is similar to Chinese medicine " spasm syndrome ", " shake is fallen ".Differentiation of disease according to pathological changes of the viscera and their disease located in liver, relates to spleen.If depression of liver-QI, fire-transformation impairment of YIN, then deficiency of liver-blood.Spleen governing muscles, if stagnation of liver-QI and spleen, causes dysfunction of the spleen in transportation, more causes QI and blood source not enough, and blood deficiency can not Ru Yangjinmai, therefore clinical manifestation is numb limbs and tense tendons, pain, reptile sample sensation etc., very then gos seesaw, increases the weight of night, impact sleep.I finds in clinical practice for many years, traditional Chinese medical herbal treatment primary disease not only good effect, and cure rate is high, and cost is low, and medicine source is wide, and without any side effects, stable curative effect, not easily recurs.
Summary of the invention
the present invention is directed to the deficiency of prior art, provide a kind of Chinese medicine for the treatment of restless legs syndrome, it is characterized in that it is made up of the component of the material medicine of following weight proportion: Radix Paeoniae Alba 30-40g, Fructus Chaenomelis 15-20g, Poria 10-15g, Rhizoma Atractylodis Macrocephalae (parched) 10-15g, Radix Angelicae Sinensis 10-15g, Radix Cyathulae 10-15g, Semen Ziziphi Spinosae 20-30g, Radix Bupleuri 6-10g, Radix Glycyrrhizae 6-10g.
preferable amount: Radix Paeoniae Alba 30g, Fructus Chaenomelis 15g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Angelicae Sinensis 10g, Radix Cyathulae 15g, Semen Ziziphi Spinosae 20g, Radix Bupleuri 6g, Radix Glycyrrhizae 6g.
pharmacology analysis: liver governing tendons, the muscle of spleen, if deficiency of liver-blood, then blood failing to nourish tendons, therefore reuse the Radix Paeoniae Alba with nourishing blood to suppress the hyperactive liver, relieving spasm to stop pain, be monarch drug.Taste are source of generating QI and blood, therefore can not only relaxing muscles and tendons and activating QI and blood in the collateral with Fructus Chaenomelis, more can regulating the function of the stomach to resolve the turbidity; Poria, Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen for eliminating dampness, as a means of the source of vital function, are ministerial drug altogether.Radix Angelicae Sinensis had not only nourished blood but also promoting blood circulation and stopping pain; The invigorating the liver and kidney again of Radix Cyathulae blood circulation promoting and blood stasis dispelling, sharp joint; Semen Ziziphi Spinosae core nourishing blood to tranquillize the mind; Radix Bupleuri and the Radix Paeoniae Alba match soothing the liver nourishing the liver, are adjuvant drug altogether.Radix Glycyrrhizae had both joined Radix Paeoniae relieving spasm to stop pain, again coordinating the actions of various ingredients in a prescription, for making medicine.Above drug combination, plays effect of nourishing blood to suppress the hyperactive liver, soothing liver and strengthening spleen, promoting blood circulation and stopping pain altogether.
dosage form and usage: our pharmaceutically dosage form is decoction, is decocted in water for oral dose, potion on the one, decocts twice.Head is decocted and is added cold water 600ml, soaks two hours, and change slow fire after intense fire boils and continue and decoct 30 minutes, extracting juice is about 200ml; Two decoct heating water 600ml, change that slow fire is continuous decocts 40 minutes after intense fire boils, and extracting juice is about 200ml.Decoct to obtain medicine juice mixing for twice, sooner or later within two hours after meal, respectively take 200ml, warm water delivery service.Period in a medicine avoids pungent food and cold and cool food.
Detailed description of the invention
below in conjunction with detailed description of the invention, the present invention will be further described:
embodiment 1: a kind of Chinese medicine for the treatment of restless legs syndrome, is made up of the component of the material medicine of following weight proportion: Radix Paeoniae Alba 30-40g, Fructus Chaenomelis 15-20g, Poria 10-15g, Rhizoma Atractylodis Macrocephalae (parched) 10-15g, Radix Angelicae Sinensis 10-15g, Radix Cyathulae 10-15g, Semen Ziziphi Spinosae 20-30g, Radix Bupleuri 6-10g, Radix Glycyrrhizae 6-10g.
embodiment 2: a kind of Chinese medicine for the treatment of restless legs syndrome, wherein preferred weight part proportioning of various material medicine is: Radix Paeoniae Alba 30g, Fructus Chaenomelis 15g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Angelicae Sinensis 10g, Radix Cyathulae 15g, Semen Ziziphi Spinosae 20g, Radix Bupleuri 6g, Radix Glycyrrhizae 6g.
clinical efficacy is summed up
one, physical data: admitted patient 18 example altogether, wherein male 8 example, women 10 example; Age 35-45 year 4 examples, 45-55 year 6 examples, more than 55 years old 8 is routine; The most elder of the course of disease 6 years, the shortest person half a year.
two, diagnostic criteria: during patient at night sleep, two lower limb have a kind of abnormal sensory that is spontaneous, insufferable misery, to climb as ant mosquito or insect stings, scratchiness, pain, twinge, burn feeling, wriggling sense etc., kicking, movable joint or massage leg can be alleviated, and thus cause sleep disorder.
three, efficacy assessment standard:
, cure: after taking medicine, subjective symptoms disappear, night normally falls asleep.
, take a turn for the better: after taking medicine, subjective symptoms alleviates, nighttime sleep improve.
, do not heal: after taking medicine, subjective symptoms is without improvement.
four, therapeutic effect: taking medicine 10 days is a course for the treatment of, the lighter one fully recovers the course for the treatment of, the severe one two recovery from illness course for the treatment of.Total effective rate 100%, cure rate 94.4%, takes a turn for the better 5.6%.
five, model case:
, Lee, female, 45 years old, peasant.On May 20th, 2012 goes to a doctor.Patient's readme started before 1 year to occur two numbness of lower limbs pain, reptile sample sensation without bright inducement, night exacerbation of symptoms, get up activity or kicking can be alleviated, and thus cause nocturnal insomnia, have a strong impact on work, feel depressed for this reason.Once took medicines such as " diazepam ", DeGrain, seeks medical advice in the traditional Chinese medical science.To have a medical check-up finding: red tongue, few tongue, tongue body is greatly more fat, stringy and thready pulse.Examine as restless legs syndrome according to its symptom, sign, give our medicine take 1 the course for the treatment of symptom subtract greatly, all diseases disappeared and fully recovered following the service 1 course for the treatment of, followed up a case by regular visits to and did not recur so far.
, Zhang, man, 60 years old, retired worker.In August, 2013 goes to a doctor.Readme is two lower limb at every night extremely discomfort over 5 years, and the place that neither one is comfortable can put both legs well, and needing gets up ceaselessly beats both legs, or ceaselessly can alleviate on foot.Cause not having enough sleep for this reason, daytime lassitude and weak, hypomnesis.Once multiple hypnotic treatment was taken invalid, very painful, sometimes even produce suicidal thought.Have a medical check-up: elderly men, body constitution is thin and weak, lassitude, red tongue, few tongue, stringy and thready pulse and weak.According to its symptom and sign, be thought of as restless legs syndrome, give our medicine and take two all disease disappearances course for the treatment of and fully recover, follow up a case by regular visits to and do not recur so far.
Claims (1)
1. treat a Chinese medicine for restless legs syndrome, it is characterized in that it is made up of the component of the material medicine of following weight proportion: Radix Paeoniae Alba 30g, Fructus Chaenomelis 15g, Poria 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Radix Angelicae Sinensis 10g, Radix Cyathulae 15g, Semen Ziziphi Spinosae 20g, Radix Bupleuri 6g, Radix Glycyrrhizae 6g.
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| CN201410225705.3A CN103948707B (en) | 2014-05-27 | 2014-05-27 | A kind of Chinese medicine for the treatment of restless legs syndrome |
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| CN103948707B true CN103948707B (en) | 2016-03-02 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497152A (en) * | 2014-11-26 | 2016-04-20 | 杨维兵 | Traditional Chinese medicine for treating restless leg syndrome |
| CN104758713A (en) * | 2015-04-26 | 2015-07-08 | 胡夫东 | Chinese medicine preparation used for restless leg syndrome and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1176796A (en) * | 1996-09-19 | 1998-03-25 | 宋宪斌 | Composite drug for treating vegetative nurve functional disturbance |
| CN1336162A (en) * | 2001-08-20 | 2002-02-20 | 杨东光 | Serial thermotherapeutic and physiotherapeutic bags |
| CN101596295A (en) * | 2009-07-03 | 2009-12-09 | 云南天秀植物科技开发有限公司 | A kind of pharmaceutical composition and preparation technology thereof who is used for the treatment of gout |
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2014
- 2014-05-27 CN CN201410225705.3A patent/CN103948707B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1176796A (en) * | 1996-09-19 | 1998-03-25 | 宋宪斌 | Composite drug for treating vegetative nurve functional disturbance |
| CN1336162A (en) * | 2001-08-20 | 2002-02-20 | 杨东光 | Serial thermotherapeutic and physiotherapeutic bags |
| CN101596295A (en) * | 2009-07-03 | 2009-12-09 | 云南天秀植物科技开发有限公司 | A kind of pharmaceutical composition and preparation technology thereof who is used for the treatment of gout |
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Inventor after: Yuan Minshao Inventor after: Lu Cuiyan Inventor before: Liu Yunjie |
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Effective date of registration: 20180926 Address after: 226499 No. twelve, group twelve, Hong Yuan village, dugong Town, Rudong County, Jiangsu Patentee after: Xi Jinming Address before: 264400 Room 201, unit 3, building 18, Xianghe Xindu District, Wendeng District, Weihai, Shandong, China Patentee before: Liu Yunjie |
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Effective date of registration: 20200316 Address after: 233000 Huahai Jinxiu facade, 3rd road, Guzhen County, Bengbu City, Anhui Province 2 uff03 105 Patentee after: Bengbu Geshi Intellectual Property Operations Co.,Ltd. Address before: 226499 No. twelve, No. 20, rainbow Yuan village, dug Town, Jiangsu County, Rudong Patentee before: Xi Jinming |
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Effective date of registration: 20221221 Address after: 252000 Building C8, Xinxing Industrial Park, southeast corner of the intersection of Wuxun Avenue and North Ring Road, Chongwen Street, Guanxian County, Liaocheng City, Shandong Province Patentee after: Zhongzhitang Pharmaceutical (Shandong) Co.,Ltd. Address before: 233000 Huahai Jinxiu facade 2 105, No. 3 Road, Guzhen County, Bengbu City, Anhui Province Patentee before: Bengbu Geshi Intellectual Property Operations Co.,Ltd. |