CN103919642A - Posterior sclera injection system - Google Patents
Posterior sclera injection system Download PDFInfo
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- CN103919642A CN103919642A CN201410095815.2A CN201410095815A CN103919642A CN 103919642 A CN103919642 A CN 103919642A CN 201410095815 A CN201410095815 A CN 201410095815A CN 103919642 A CN103919642 A CN 103919642A
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- 238000002347 injection Methods 0.000 title claims abstract description 65
- 239000007924 injection Substances 0.000 title claims abstract description 65
- 210000003786 sclera Anatomy 0.000 title claims abstract description 13
- 238000001802 infusion Methods 0.000 claims abstract description 45
- 239000007788 liquid Substances 0.000 claims abstract description 15
- 210000005252 bulbus oculi Anatomy 0.000 claims abstract description 9
- 238000003032 molecular docking Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 28
- 208000015181 infectious disease Diseases 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 4
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- 230000000630 rising effect Effects 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 15
- 239000000243 solution Substances 0.000 description 6
- 206010025421 Macule Diseases 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 230000004406 elevated intraocular pressure Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
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- 230000006838 adverse reaction Effects 0.000 description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
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- 210000001328 optic nerve Anatomy 0.000 description 2
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- 201000004569 Blindness Diseases 0.000 description 1
- 208000001344 Macular Edema Diseases 0.000 description 1
- 206010025415 Macular oedema Diseases 0.000 description 1
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- 229940121657 clinical drug Drugs 0.000 description 1
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- 238000001647 drug administration Methods 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000001508 eye Anatomy 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
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Abstract
Description
技术领域technical field
本发明涉及一种注射系统，特别涉及一种专门用于巩膜后药物注射的注射系统。The invention relates to an injection system, in particular to an injection system specially used for retroscleral drug injection.
背景技术Background technique
各种眼底疾病常累及黄斑区，黄斑水肿是导致中央视力下降的直接原因，严重影响患者的日常生活。目前临床上常用的治疗方法存在一定的局限和不足：玻璃体腔注射药物有眼内感染、眼压升高的风险；球后或后腾氏囊注射有刺破眼球的风险，为避免此风险则注射部位不能紧邻黄斑导致疗效不佳；则球周注射距离黄斑更远，疗效更差。这些治疗方法的缺陷主要是由于缺乏有效的专门用于巩膜后药物注射系统导致的，那么寻找经济安全、成本低廉而又有效的注射系统就成为目前亟待解决的问题。Various fundus diseases often involve the macular area, and macular edema is the direct cause of central vision loss, which seriously affects the daily life of patients. There are certain limitations and deficiencies in the currently commonly used clinical treatment methods: intravitreal injection of drugs has the risk of intraocular infection and increased intraocular pressure; injection of retrobulbar or posterior Teng's capsule has the risk of puncturing the eyeball. To avoid this risk, If the injection site cannot be close to the macula, the curative effect will be poor; if the peribulbar injection is farther away from the macula, the curative effect will be worse. The defects of these treatment methods are mainly caused by the lack of an effective drug injection system specially used for retrosclera, so finding an economical, safe, low-cost and effective injection system has become an urgent problem to be solved.
因此，有必要开发一种专门用于巩膜后药物注射的注射系统，能够为术者顺利完成眼药物注射，使药物尽可能充分地被吸收，并能有效避免或者降低感染及眼压升高的风险，以保证良好的治疗效果。Therefore, it is necessary to develop an injection system specially used for retroscleral drug injection, which can successfully complete ocular drug injection for the operator, make the drug fully absorbed as much as possible, and effectively avoid or reduce the risk of infection and elevated intraocular pressure. risk in order to ensure a good therapeutic effect.
发明内容Contents of the invention
有鉴于此，本发明的目的在于提供一种专门用于巩膜后药物注射的注射系统，能够为术者顺利完成眼药物注射，使药物尽可能充分地被吸收，并能有效避免或者降低感染及眼压升高的风险，以保证良好的治疗效果。In view of this, the object of the present invention is to provide an injection system specially used for retroscleral drug injection, which can successfully complete eye drug injection for the operator, make the drug fully absorbed as much as possible, and effectively avoid or reduce infection and Risk of increased intraocular pressure to ensure good therapeutic effect.
本发明的巩膜后注射系统，包括依次连接的注射针头、输液管和输液泵，所述注射针头的内部中空且包括一体成型的平直管和弧形管，所述弧形管的弧度与人体眼球外壁的弧度相适应，所述平直管的一端与所述弧形管圆滑过渡连接且具有105°-150°的夹角，所述平直管的另一端与所述输液管的输出端连接，所述弧形管的前端开有用于输出药液的注射孔。The retroscleral injection system of the present invention includes injection needles, infusion tubes and infusion pumps connected in sequence, the interior of the injection needles is hollow and includes integrally formed straight tubes and arc tubes, and the curvature of the arc tubes is similar to that of the human body. The curvature of the outer wall of the eyeball is adapted, one end of the straight tube is smoothly transitioned to the arc tube and has an included angle of 105°-150°, the other end of the straight tube is connected to the output end of the infusion tube The front end of the arc tube is provided with an injection hole for outputting medicinal liquid.
进一步，所述注射孔为所述弧形管的顶端开口；或者，所述弧形管的顶端闭合，所述注射孔数量为一个且开设在所述弧形管的内侧，所述弧形管的顶端闭合面为一弧形面。Further, the injection hole is an opening at the top of the arc tube; or, the top end of the arc tube is closed, the number of the injection hole is one and it is opened inside the arc tube, and the arc tube The top closed surface of is an arc surface.
进一步，所述平直管上设有刻度线。Further, the straight tube is provided with scale marks.
进一步，本发明的巩膜后注射系统还包括设有中空腔体的操作手柄，所述平直管上与所述输液管对接的一端设有用于与操作手柄连接的衔接器，所述输液管穿过所述中空腔体并伸入所述平直管的内部。Further, the retroscleral injection system of the present invention also includes an operating handle with a hollow cavity, and an adapter for connecting with the operating handle is provided at the end of the straight tube that is connected to the infusion tube, and the infusion tube passes through through the hollow cavity and extend into the inside of the straight tube.
进一步，所述输液泵包括泵壳、固定在所述泵壳上的针筒、滑动设置在所述针筒中的推杆和用于驱动所述推杆沿所述针筒的轴向运动的传动件，所述针筒的出口端与所述输液管的输入端连接。Further, the infusion pump includes a pump casing, a syringe fixed on the pump casing, a push rod slidably arranged in the syringe, and a transmission for driving the push rod to move along the axial direction of the syringe. The outlet end of the syringe is connected with the input end of the infusion tube.
进一步，本发明的巩膜后注射系统还包括三通管和辅助注射器，所述三通管包括相互贯通的第一通管、第二通管和第三通管，所述第一通管和第二通管位于同一水平线上，且所述第一通管和第二通管分别位于所述第三通管的两端，所述第一通管的轴心线和所述第二通管的轴心线为同一条线，所述第三通管的轴心线垂直于所述第一通管的轴心线，所述第一通管与所述针筒的出口端连接，所述第二通管与所述输液管的输入端连接，所述第三通管与所述辅助注射器连接。Further, the retroscleral injection system of the present invention also includes a three-way tube and an auxiliary injector, the three-way tube includes a first through tube, a second through tube and a third through tube that communicate with each other, and the first through tube and the third through tube The two-way pipes are located on the same horizontal line, and the first through-pipe and the second through-pipe are respectively located at both ends of the third through-pipe, the axis line of the first through-pipe and the axis of the second through-pipe The axis lines are the same line, the axis line of the third through pipe is perpendicular to the axis line of the first through pipe, the first through pipe is connected with the outlet end of the syringe, and the first through pipe is connected to the outlet end of the syringe. The two-way tube is connected to the input end of the infusion tube, and the third-way tube is connected to the auxiliary syringe.
进一步，所述输液管包括第一导管和第二导管，所述第二导管的管径大于所述第一导管的管径，且所述第二导管的两端均设有用于分别与所述第一导管、第二通管连接的连接针。Further, the infusion tube includes a first conduit and a second conduit, the diameter of the second conduit is larger than the diameter of the first conduit, and both ends of the second conduit are respectively provided with A connecting needle for connecting the first catheter and the second through pipe.
本发明的有益效果：本发明的巩膜后注射系统，通过将注射针头设计成平直管与弧形管的两段管结构，使用时弧形管经过颞侧沿眼球弧度向内进针，直至注射孔进入至黄斑部后方时输出药液，可使药物尽可能充分地被吸收、药效最为明显，同时又避免了眼内感染、眼压升高等不良反应的产生，保证良好的治疗效果；配合输液泵能够准确控制输液滴数或输液流速，保证药物能够速度均匀、药量准确并且安全地进入病人体内发挥作用。Beneficial effects of the present invention: the post-scleral injection system of the present invention designs the injection needle as a two-section tube structure of a straight tube and an arc tube. When the injection hole enters the back of the macula, the drug liquid can be output, so that the drug can be absorbed as much as possible, and the drug effect is the most obvious, and at the same time avoid the occurrence of adverse reactions such as intraocular infection and elevated intraocular pressure, ensuring a good therapeutic effect; Cooperating with the infusion pump, it can accurately control the number of infusion drops or the infusion flow rate, so as to ensure that the medicine can enter the patient's body safely and play a role at a uniform speed and accurate dosage.
附图说明Description of drawings
下面结合附图和实施例对本发明作进一步描述：The present invention will be further described below in conjunction with accompanying drawing and embodiment:
图1为本发明的结构示意图；Fig. 1 is a structural representation of the present invention;
图2为本发明的注射针头的结构示意图。Fig. 2 is a schematic structural view of the injection needle of the present invention.
具体实施方式Detailed ways
图1为本发明的结构示意图，图2为本发明的注射针头的结构示意图，如图所示：本实施例的巩膜后注射系统，包括依次连接的注射针头1、输液管2和输液泵3，所述注射针头1的内部中空且包括一体成型的平直管11和弧形管12，所述弧形管12的弧度与人体眼球外壁的弧度相适应，所述平直管11的一端与所述弧形管12圆滑过渡连接且具有105°-150°的夹角，所述平直管11的另一端与所述输液管2的输出端连接，所述弧形管12的前端开有用于输出药液的注射孔12a；注射针头1呈弯钩形，包括平直管1和弧形管2，平直管1为直线形，弧形管2则根据患者眼球的情况具有不同的弧形弯曲度，而且可以根据个体差异进行度数的微调；平直管1和弧形管2的中空管体的对接，在制造时一体成型化，以保证注射针头1的强度和内部密封度；平直管1与弧形管2之间的夹角即平直管1轴线与弧形管2在连接点的切线的夹角，可在105°-150°之间选择，本实施例优选为125°，该角度能适合大多数患者使用；弧形管2的前端即距离弧形管2顶端较近的部分，此处特指为距离弧形管2顶端5mm的范围内；注射孔4为圆孔，便于加工制造；输液管2为两端开口的空心软管，采用医用级PVC材料制成，其输入端、输出端均是根据药液流动方向相对而言，即与注射针头1连接的一端即为输出端，与注射器连接的一端即为输入端；注射器设在输液泵3上并受输液泵3的控制；将注射针头1设计成平直管11与弧形管12的两段管结构，使用时弧形管12经过颞侧沿眼球弧度向内进针，直至注射孔12a进入至黄斑部后方时输出药液，可使药物尽可能充分地被吸收、药效最为明显，同时又避免了眼内感染、眼压升高等不良反应的产生，保证良好的治疗效果；配合输液泵3能够准确控制输液滴数或输液流速，保证药物能够速度均匀、药量准确并且安全地进入病人体内发挥作用，而且输液泵3还能提高临床给药操作的效率和灵活性，降低护理工作量。Figure 1 is a schematic structural view of the present invention, and Figure 2 is a schematic structural view of the injection needle of the present invention, as shown in the figure: the retroscleral injection system of this embodiment includes an injection needle 1, an infusion tube 2 and an infusion pump 3 connected in sequence The interior of the injection needle 1 is hollow and includes an integrally formed straight tube 11 and an arc-shaped tube 12, the arc of the arc-shaped tube 12 is adapted to the arc of the outer wall of the human eyeball, and one end of the straight tube 11 is connected to the The arc tube 12 is connected smoothly and has an included angle of 105°-150°, the other end of the straight tube 11 is connected to the output end of the infusion tube 2, and the front end of the arc tube 12 is opened for use. Injection hole 12a for outputting liquid medicine; injection needle 1 is in the shape of a hook, including straight tube 1 and arc tube 2, straight tube 1 is straight, and arc tube 2 has different arcs according to the condition of the patient's eyeball The curvature of the shape can be fine-tuned according to individual differences; the butt joint of the hollow tube body of the straight tube 1 and the curved tube 2 is integrally formed during manufacture to ensure the strength and internal sealing of the injection needle 1; The angle between the straight tube 1 and the arc tube 2, that is, the angle between the axis of the straight tube 1 and the tangent of the arc tube 2 at the connection point, can be selected between 105°-150°. In this embodiment, it is preferably 125°, this angle can be used by most patients; the front end of the arc tube 2 is the part closer to the top of the arc tube 2, here specifically refers to the range within 5mm from the top of the arc tube 2; the injection hole 4 is The round hole is convenient for processing and manufacturing; the infusion tube 2 is a hollow hose with openings at both ends, made of medical-grade PVC material, and its input and output ends are relative to the flow direction of the liquid medicine, that is, connected to the injection needle 1 One end is the output end, and the end connected to the syringe is the input end; the syringe is set on the infusion pump 3 and is controlled by the infusion pump 3; the injection needle 1 is designed as two sections of a straight tube 11 and an arc tube 12 The tube structure, when in use, the arc tube 12 passes through the temporal side and inserts the needle inward along the arc of the eyeball, until the injection hole 12a enters the back of the macula and outputs the drug solution, so that the drug can be absorbed as fully as possible and the drug effect is the most obvious. It also avoids the occurrence of adverse reactions such as intraocular infection and elevated intraocular pressure, and ensures a good therapeutic effect; cooperates with the infusion pump 3 to accurately control the number of infusion drops or the flow rate of the infusion, ensuring that the drug can enter the patient safely with uniform speed and accurate dosage It works in the body, and the infusion pump 3 can also improve the efficiency and flexibility of clinical drug administration operations, and reduce the nursing workload.
本实施例中，所述弧形管12的顶端闭合，所述注射孔12a数量为一个且开设在所述弧形管12的内侧；弧形管12的内侧即弧形管12弯向平直管11的一侧；注射孔12a的数量太多容易阻碍到药液的流动，而且考虑到弧形管12的宽度有限，注射孔12a只需开设一个、满足输出药液的功能即可；弧形管12的顶端闭合，避免了注射孔12a输出药液时对视神经造成冲击而损伤视神经；注射孔12a优选开设在距离弧形管12顶端2mm至4mm处，而且注射孔12a的位置应与眼球黄斑部对应，以使药物尽可能充分地被吸收；当然，注射孔12a也可以为弧形管12的顶端开口，便于加工制造。In this embodiment, the top end of the arc tube 12 is closed, and the number of the injection holes 12a is one and set on the inner side of the arc tube 12; the inner side of the arc tube 12, that is, the arc tube 12 is bent straight One side of the tube 11; too many injection holes 12a will easily hinder the flow of the medicinal solution, and considering the limited width of the arc-shaped tube 12, only one injection hole 12a is required to meet the function of outputting the medicinal solution; The top of the shaped tube 12 is closed, which avoids the impact on the optic nerve when the injection hole 12a outputs the medicinal liquid and damages the optic nerve; the injection hole 12a is preferably set at 2mm to 4mm from the top of the arc tube 12, and the position of the injection hole 12a should be in line with the eyeball. The macula is corresponding so that the drug can be absorbed as fully as possible; of course, the injection hole 12a can also be an opening at the top of the arc-shaped tube 12, which is convenient for processing and manufacturing.
本实施例中，所述弧形管12的顶端闭合面为一弧形面；弧形闭合面使弧形管12的顶端具有钝性，避免在进针时刺伤巩膜及血管、神经组织，进一步降低手术风险；至于该弧形面的弧度则可根据具体情况选择，优选为半圆。In this embodiment, the closed surface of the top of the arc-shaped tube 12 is an arc-shaped surface; the arc-shaped closed surface makes the top of the arc-shaped tube 12 blunt, so as to avoid stabbing the sclera, blood vessels and nerve tissues when the needle is inserted. The operation risk is further reduced; as for the radian of the arc surface, it can be selected according to the actual situation, preferably a semicircle.
本实施例中，所述平直管11上设有刻度线11a；刻度线11a为毫米刻度线，以平直管11的末端为零点，方便治疗时医务人员观察进针深度，并准确停止进针，以达到准确治疗的效果。In this embodiment, the straight tube 11 is provided with a scale line 11a; the scale line 11a is a millimeter scale line, and the end of the straight tube 11 is used as the zero point, so that the medical staff can observe the depth of the needle during treatment and stop the needle accurately. Needles for accurate treatment.
本实施例中，本巩膜后注射系统还包括设有中空腔体（图中未示出）的操作手柄4，所述平直管11上与所述输液管2对接的一端设有用于与操作手柄4连接的衔接器13，所述输液管2穿过所述中空腔体并伸入所述平直管11的内部；操作手柄4便于对注射针头1的进针操作进行控制，以准确执行手术；衔接器13可与任何普通注射用针筒匹配，一端连接在平直管11尾端，另一端通过内螺纹与操作手柄4的头部固定连接，或者直接套接在操作手柄4上；中空腔体既可以是贯穿整个操作手柄4的中空部分，也可以是操作手柄4中的某一段，只要能供输液管2穿过即可；为增强摩擦性能，操作手柄4上设置防滑纹41；为了能对输液进行紧急中断，操作手柄4上设置与中空腔体连通的柔性控制块，挤压控制块即可使输液管2中的药液流动。In this embodiment, the retroscleral injection system also includes an operating handle 4 with a hollow cavity (not shown in the figure), and the end of the straight tube 11 that is connected to the infusion tube 2 is provided with a The adapter 13 connected to the handle 4, the infusion tube 2 passes through the hollow cavity and extends into the inside of the straight tube 11; the operating handle 4 facilitates the control of the needle insertion operation of the injection needle 1 to accurately perform Surgery; the adapter 13 can be matched with any common injection syringe, one end is connected to the tail end of the straight tube 11, and the other end is fixedly connected to the head of the operating handle 4 through an internal thread, or directly sleeved on the operating handle 4; The hollow cavity can be a hollow part that runs through the entire operating handle 4, or it can be a certain section in the operating handle 4, as long as it can pass through the infusion tube 2; in order to enhance the friction performance, the operating handle 4 is provided with anti-slip lines 41 ; In order to interrupt the infusion urgently, a flexible control block communicating with the hollow cavity is set on the operating handle 4, and the liquid medicine in the infusion tube 2 can be made to flow by squeezing the control block.
本实施例中，所述输液泵3包括泵壳31、固定在所述泵壳31上的针筒32、滑动设置在所述针筒32中的推杆33和用于驱动所述推杆33沿所述针筒32的轴向运动的传动件34，所述针筒32的出口端与所述输液管2的输入端连接；针筒32与推杆33组成注射器，其中针筒32内储存药液，推杆33则用于将药液推注出去；输液泵3与现有的智能推注泵结构相同，其外部设有显示面板和操作按钮、内部设有控制传动件34运动的驱动电机及控制系统，在此不再赘述；输液泵3能够准确控制输液滴数或输液流速，保证药物能够速度均匀、药量准确并且安全地进入病人体内发挥作用，而且输液泵3还能提高临床给药操作的效率和灵活性，降低护理工作量。In this embodiment, the infusion pump 3 includes a pump casing 31, a syringe 32 fixed on the pump casing 31, a push rod 33 slidably arranged in the syringe 32, and a push rod 33 for driving the push rod 33. The transmission member 34 moving along the axial direction of the syringe 32, the outlet end of the syringe 32 is connected to the input end of the infusion tube 2; the syringe 32 and the push rod 33 form a syringe, wherein the syringe 32 stores The liquid medicine, the push rod 33 is used to push the liquid medicine out; the infusion pump 3 has the same structure as the existing intelligent injection pump, and the outside is provided with a display panel and operation buttons, and the inside is provided with a drive for controlling the movement of the transmission member 34. The motor and control system will not be described in detail here; the infusion pump 3 can accurately control the number of infusion drops or the flow rate of the infusion, so as to ensure that the medicine can enter the patient's body with a uniform speed and an accurate dose to play a role safely, and the infusion pump 3 can also improve clinical performance. The efficiency and flexibility of the drug delivery operation can reduce the nursing workload.
本实施例中，本巩膜后注射系统还包括三通管和辅助注射器6，所述三通管包括相互贯通的第一通管51、第二通管52和第三通管53，所述第一通管51和第二通管52位于同一水平线上，且所述第一通管51和第二通管52分别位于所述第三通管53的两端，所述第一通管51的轴心线和所述第二通管52的轴心线为同一条线，所述第三通管53的轴心线垂直于所述第一通管51的轴心线，所述第一通管51与所述针筒的出口端连接，所述第二通管52与所述输液管2的输入端连接，所述第三通管53与所述辅助注射器连接；三通管和辅助注射器6的设置便于根据病情需要同时输入多种药液，便于在手术中给药。In this embodiment, the retroscleral injection system further includes a three-way tube and an auxiliary injector 6, the three-way tube includes a first through tube 51, a second through tube 52 and a third through tube 53 that communicate with each other, and the first through tube 53 communicates with each other. A through pipe 51 and a second through pipe 52 are located on the same horizontal line, and the first through pipe 51 and the second through pipe 52 are located at the two ends of the third through pipe 53 respectively, and the first through pipe 51 The axis line and the axis line of the second through pipe 52 are the same line, the axis line of the third through pipe 53 is perpendicular to the axis line of the first through pipe 51, and the first through pipe 51 The tube 51 is connected with the outlet end of the syringe, the second through pipe 52 is connected with the input end of the infusion tube 2, and the third through pipe 53 is connected with the auxiliary syringe; the three-way pipe and the auxiliary syringe The setting of 6 is convenient for simultaneously inputting multiple medicinal liquids according to the needs of the disease, and is convenient for administering medicine in the operation.
本实施例中，所述输液管2包括第一导管21和第二导管22，所述第二导管22的管径大于所述第一导管21的管径，且所述第二导管22的两端均设有用于分别与所述第一导管21、第二通管52连接的连接针7；输液管2为两段管式结构，满足输液长度需要，连接针7则便于根据需要进行拆卸和连接；第一导管21和第二导管22在管径上的差异使得药液在输送过程中流速得以改变。In this embodiment, the infusion tube 2 includes a first conduit 21 and a second conduit 22, the diameter of the second conduit 22 is larger than the diameter of the first conduit 21, and the two diameters of the second conduit 22 Each end is provided with a connecting needle 7 for connecting with the first conduit 21 and the second through pipe 52 respectively; the infusion tube 2 is a two-section tubular structure, which meets the needs of the infusion length, and the connecting needle 7 is convenient for disassembly and assembly as required. Connection; the difference in diameter between the first conduit 21 and the second conduit 22 makes the flow rate of the liquid medicine change during delivery.
最后说明的是，以上实施例仅用以说明本发明的技术方案而非限制，尽管参照较佳实施例对本发明进行了详细说明，本领域的普通技术人员应当理解，可以对本发明的技术方案进行修改或者等同替换，而不脱离本发明技术方案的宗旨和范围，其均应涵盖在本发明的权利要求范围当中。Finally, it is noted that the above embodiments are only used to illustrate the technical solutions of the present invention without limitation. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be carried out Modifications or equivalent replacements without departing from the spirit and scope of the technical solution of the present invention shall be covered by the claims of the present invention.
Claims (9)
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