CN103918740A - Premixed powder for preventing and treating hyperglycemia - Google Patents

Premixed powder for preventing and treating hyperglycemia Download PDF

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Publication number
CN103918740A
CN103918740A CN201410179948.8A CN201410179948A CN103918740A CN 103918740 A CN103918740 A CN 103918740A CN 201410179948 A CN201410179948 A CN 201410179948A CN 103918740 A CN103918740 A CN 103918740A
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powder
liquid extract
lycopodium calvatum
dry powder
preventing
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CN201410179948.8A
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Chinese (zh)
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杨玉相
其他发明人请求不公开姓名
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Abstract

The invention relates to premixed powder for preventing and treating hyperglycemia. The premixed powder comprises, by weight, 10-20% of lycopodium clavatum liquid extract dry powder, 1-5% of wheat gluten powder, 4-10% of xylitol, 0.5-3% of refined salt, 0.01-1% of bread powder modifying agent and 100% of flour. The premixed powder is sweet, mellow and fresh, and new tastes are added for the premixed powder. The premixed powder has the effects of relaxing the muscles and stimulating the blood circulation, eliminating phlegm and resolving turbidity and reducing blood sugar and is suitable for preventing and treating the hyperglycemia.

Description

Prevent and treat the premixed powder of hyperglycaemia
Technical field
The present invention relates to a kind of premixed powder, especially a kind of premixed powder of preventing and treating hyperglycaemia.
Background technology
Hyperphagia sweet food or Sugared beverages cause one of reason of hyperglycaemia.Under normal circumstances, human body can be regulated with this two large regulating system of nerve modulation and be guaranteed that the source of blood sugar and outlet keep balance, make blood sugar maintain certain level by hormone.But under the acting in conjunction of inherent cause (as diabetes family history) and environmental factor (as irrational meals, obesity etc.), two large regulatory functions get muddled, and just there will be the rising of blood sugar level.Long-term hyperglycaemia can make each histoorgan generation pathology of whole body, causes the generation of acute and chronic complication.As pancreas function exhaustion, dehydration, electrolyte disturbance, nutritional deficiency, resistance decline, impaired renal function, DPN, eyeground pathological changes etc.Controlling hyperglycaemia becomes the important topic of people's daily health caring.
Diabetes are mainly that the five internal organs are weak due to the plain body deficiency of Yin in the traditional Chinese medical science, multiple because of eating and drinking without temperance, overfeeding delicious food, and disorder of emotion, labor is wanted excessively, and causes deficiency of kidney-YIN, and lung stomach is scorching; Interpretation of the cause, onset and process of an illness emphasis is that the deficiency of Yin is scorching, and take the deficiency of Yin as this, and scorching is mark; With the passing of time disease prolongs, yin deficiency affecting yang, deficiency in both YIN and YANG; The deficiency of Yin is scorching, and the bright liquid in consumption Tianjin makes blood viscous, the not smooth stasis of blood that forms of blood; Yin deficiency affecting yang, the deficiency of yang is cold solidifying, also can cause sun in hemostasis.
Prior art is not applied the premixed powder that lycopodium calvatum preparation prevents and treats hyperglycaemia, and the single and health care of taste has its limitation.The invention that the patent No. that Ru Chinese patent information centre announces is 00310120014---have the bread premixed powder of health care, hawthorn powder, pumpkin powder, yam flour and other batching powder are selected in this invention, and health-care efficacy has its limitation.
Summary of the invention
The object of the invention is to provide a kind of premixed powder of preventing and treating hyperglycaemia, to prevent people cause disease because blood sugar raises, for the treatment of the diabetes state of an illness, also play health care booster action.
Technical scheme: a kind of premixed powder of preventing and treating hyperglycaemia, by preparing burden and form by weight percentage below, comprise that 10-20% lycopodium calvatum liquid extract dry powder, 1-5% wheat gluten, the xylitol of 4-10%, the bread flour improver of the refined salt of 0.5-3%, 0.01-1%, flour add to very; Described lycopodium calvatum liquid extract dry powder is made after liquid extract the freezing dry powder that is ground into again by the composition of raw materials of following weight portion: lycopodium calvatum 10-20, frangipanis 8-20, Radix Glycyrrhizae 3-10, seed of Chinese dodder 5-10, Poria cocos 10-20, tuber of dwarf lilyturf 5-10.
Preparation method is: while producing this premixed powder, each component mixed in proportion, then stir.The technique of making bread, cake completes according to routine operation.
As optimization, a kind of premixed powder of preventing and treating hyperglycaemia, by preparing burden and form by weight percentage below, comprise that 10-20% lycopodium calvatum liquid extract dry powder, 1-5% wheat gluten, the xylitol of 4-10%, the bread flour improver of the refined salt of 0.5-3%, 0.01-1%, flour add to very; Described lycopodium calvatum liquid extract dry powder is made after liquid extract the freezing dry powder that is ground into again by the composition of raw materials of following weight portion: lycopodium calvatum 10-20, frangipanis 8-20, Radix Glycyrrhizae 3-10, seed of Chinese dodder 5-10, Poria cocos 10-20, tuber of dwarf lilyturf 5-10, rush 3-5, dark plum 3-10.
Lycopodium calvatum, toil temperature, expelling wind and clearing away cold, dehumidifying are subsided a swelling, are stimulated the circulation of the blood and cause the muscles and joints to relax.< < Hunan medicine will > > records lycopodium calvatum: sweet, flat.Nontoxic, enter the heart, kidney two warps, relax the muscles and stimulate the blood circulation, invigorating qi and dredging collateral.
Frangipanis, cool in nature, taste is sweet, light; Return large intestine, stomach warp, there is the effect of moistening lung removing toxic substances, clearing heat and expelling damp, laxation.
Radix Glycyrrhizae taste is sweet, flat.The thoughts of returning home, lung, spleen, stomach warp.Function cures mainly: invigorates the spleen and benefits qi, and clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, the anxious pain of four limbs contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Seed of Chinese dodder acrid-sweet flavor, property is flat, enters liver, kidney two warps.There is tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity, antiabortive effect.
Poria cocos taste is sweet, light, property is flat, be used as medicine there is clearing damp and promoting diuresis, the function of beneficial spleen and stomach, antitoxic heart-soothing and sedative.Modern medicine study: Poria cocos energy enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect.
The tuber of dwarf lilyturf, the micro-sugariness of property is bitter, cold, has nourishing Yin and moistening lung, reinforcing stomach reg fluid, the relieving restlessness that clears away heart-fire, reinforcing yin essence benefit essence, five viscera settling effect.
Rush, is slightly cold; Sweet, light; The thoughts of returning home; Lung; Small intestine; Urinary bladder channel.Effect: promoting diuresis for stranguria; Clearing heart fire.Dark plum is sour, puckery, flat, returns liver, spleen, lung, large intestine channel.[function cures mainly] astringes the lung, and puckery intestines, promote the production of body fluid, claming ascaris.For chronic cough of deficiency lung, protracted dysentery laxation, abnormal heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache, ascariasis of biliary tract (< < Chinese pharmacopoeia > >).
Advantage of the present invention: 1, lycopodium calvatum Xin Wenyi impairment of yin blood of the present invention, therefore adapted frangipanis, Radix Glycyrrhizae are in harmonious proportion, make its institute partially, its taste is glycol, fresh and sweet, has channels sootheing and network vessel quickening, function of promoting blood circulation to disperse blood clots.
2, taste glycol of the present invention is pure and fresh, has increased the novel taste of premixed powder.Seed of Chinese dodder tonifying kidney and benefiting sperm, Poria cocos clearing damp and promoting diuresis, beneficial spleen and stomach, the tuber of dwarf lilyturf is nourishing Yin and moistening lung, reinforcing stomach reg fluid, the relieving restlessness that clears away heart-fire, and rush clearing heart fire, dark plum are quenched one's thirst and are brought down a fever, and more contribute to promoting blood circulation and removing blood stasis hypoglycemic.
3, the present invention is by the balance of frangipanis, the seed of Chinese dodder, Poria cocos, the tuber of dwarf lilyturf, rush conditioning human body-centered liver spleen lung kidney the five internal organs, and stagnation resolvation is pure and impure quenches one's thirst, and relax the muscles and stimulate the blood circulation again, thereby invigorating qi and dredging collateral reaches hypoglycemic object with lycopodium calvatum.
4, Chinese medicine powder of the present invention has significant hypoglycemic activity to adrenaline hyperglycaemia mouse and alloxan hyperglycemia mouse.Each 20 of male and female mices are selected in experiment; Adopt respectively adrenaline and alloxan to set up hyperglycaemia mouse model, then give Chinese medicine powder of the present invention, glibenclamide, insoral is treated and survey blood sugar level.In the hyperglycemia mouse of bringing out at adrenaline, Chinese medicine powder of the present invention can make fasting serum glucose [(16. 58 ± 3. 92) mmol/L] be reduced to (7. 56 ± 2. 63) mmol/L, effect and glibenclamide comparison, no significant difference (P>0.05); In the hyperglycemia mouse of model induced by alloxan, the present invention is reduced to fasting serum glucose [(15. 56 ± 1. 83) mmol/L] (7. 55 ± 1.65) mmol/L, blood sugar reducing function is significantly better than insoral (P<0 05), and causes hypoglycemic side effect without glibenclamide.Conclusion: the present invention can significantly reduce the blood sugar level (P <0. 001) of 2 kinds of modeling animals, and makes blood sugar be down to normal level.
5, Chinese medicine powder of the present invention shows through more than the 60 routine sugared dung patients' that make a definite diagnosis clinical observation on the therapeutic effect, and the present invention has remarkable reduction glycosuria patient's blood sugar level, makes blood sugar recovery normal.
Clinical observation result of the present invention:
1.1 physical data: select the People's Hospital, city outpatient service diabetes B patient 60 examples, be divided at random two groups.Treatment group 30 examples, male 16 examples, female's 14 examples, 30~70 years old age, average (50 ± 1.5) year, the course of disease 6 months~15 years, average (8.0 ± 1.2) year; Control group 30 examples, male 18 examples, female's 12 examples, 29~70 years old age.Two groups of physical data comparing difference not statistically significants (P>0.05), have comparativity.
1.2 case selections: with reference to the World Health Organization's (WHO) diabetes diagnosis in 1999 and somatotype standard [1]: diabetic symptom+random time plasma glucose levels >=11.1mmol/L(200mg/dl).The patient's random packet that meets above-mentioned standard is carried out to observational study, and the patient that part takes traditional Chinese medicine stops former Chinese medicine and includes observation in after 2 weeks, and the patient's to be directly brought into not taking traditional Chinese medicine is observed.Two groups of patients all give diabetes Primary Care, comprise diet control, kinesiatrics and orally-taken blood sugar reducing Western medicine, and hypoglycemic Western medicine adopts melbine, according to blood sugar situation, carries out drug usage and dose adjustment.
1.3 methods of treatments: treatment group is taken Chinese medicine powder of the present invention taking on the basis of melbine.Basic side is comprised of the composition of raw materials of following weight portion: lycopodium calvatum 10, frangipanis 10, Radix Glycyrrhizae 3, the seed of Chinese dodder 5, Poria cocos 10, the tuber of dwarf lilyturf 5; Every natural gift are taken for three times, each 4 grams.Control group routine is taken melbine.Two groups are consistent in diet control, kinesiatrics, and be 2 months two groups of courses for the treatment of.
1.4 observation index: measure respectively fasting blood-glucose (FPG), postprandial blood sugar (2hBG), glycosylated hemoglobin (HbA1c), FPI (FINS), blood fat (TC, TG, HDL-C, LDL-C) before and after treatment, blood sugar determination of glucose oxidase, insulin is measured with putting the method for exempting from, blood fat is measured with automatic clinical chemistry analyzer, HOMA-IR employing Haffner etc. [3,4] in Homa model, calculate the formula of IR, be HOMA-IR=FPG * FINS/22.5 (FPG unit is mmol/L, and FINS unit is mU/L).
1.5 statistical methods: adopt SPSS 14.0 statistical analysis softwares to carry out statistical procedures.Measurement data adopts t check, enumeration data chi-square criterion.
2 results: before and after two groups of treatments, the variation of FPG, 2hBG, HbAIc, FINS and HOMA-IR refers to table 1.By in table 1, we can see, treat front two groups of patient FPG, 2hBG, HbAlc, FINS, the horizontal comparing difference not statistically significant of HOMA-IR (P>0.05); After treating, two groups of FPG, 2hBG, HbAlc, FINS, HOMA-IR levels have statistical significance (P<0.05 or P<0.01) with the front comparing differences for the treatment of, before treatment group patient's These parameters and treatment, relatively have significant difference (P<0.01).Prompting treatment group and control group all can reduce diabetes blood sugar, but it is more obvious with treatment group, to improve blood sugar.
The variation of FPG, 2hBG, HbAlc, FINS and HOMA-IR before and after table 1 liang group patient treatment
Note: indices is compared with before treatment: * P<0.05, * * P<0.01; The rear two groups of FINS for the treatment of and HOMA-IR compare ^P<0.05, ^^P<0.01.
Before and after two groups of patient treatments, the variation of TC, TG, HDL-C, LDL-C is in Table 2.From table 2, we can see the front two groups of patients' for the treatment of the horizontal comparing difference not statistically significant of TC, TG, HDL-C, LDL-C (P>0.05); After treatment, TC, TG, HDL-C, the LDL-C level of two groups have significant change, wherein TC, TG, LDL-C level have statistical significance (P<0.05) with the front comparing difference for the treatment of, and relatively have significant difference (P<0.01) before treatment group HDL-C level and treatment.Illustrate that treatment group and control group all can improve diabetic's blood lipid level, and more remarkable with treatment group effect.
The variation of TC, TG, HDL-C, the horizontal content of LDL-C before and after table 2 liang group patient treatment
Note: indices is compared with before treatment: * P<0.05, * * P<0.01; After treatment, two groups of indices are compared ^P<0.05, ^^P<0.01.
The specific embodiment
Embodiment 1: a kind of premixed powder of preventing and treating hyperglycaemia, by preparing burden and form by weight percentage below, comprise that 10-20% lycopodium calvatum liquid extract dry powder, 1-5% wheat gluten, the xylitol of 4-10%, the bread flour improver of the refined salt of 0.5-3%, 0.01-1%, flour add to very; Described lycopodium calvatum liquid extract dry powder is made after liquid extract the freezing dry powder that is ground into again by the composition of raw materials of following weight portion: lycopodium calvatum 10-20, frangipanis 8-20, Radix Glycyrrhizae 3-10, seed of Chinese dodder 5-10, Poria cocos 10-20, tuber of dwarf lilyturf 5-10.
Preparation method is: above each component batching mixed in proportion, then stir.The technique of making bread, cake completes according to routine operation.
Embodiment 2: a kind of premixed powder of preventing and treating hyperglycaemia, by preparing burden and form by weight percentage below, comprise that 10-20% lycopodium calvatum liquid extract dry powder, 1-5% wheat gluten, the xylitol of 4-10%, the bread flour improver of the refined salt of 0.5-3%, 0.01-1%, flour add to very; Described lycopodium calvatum liquid extract dry powder is made after liquid extract the freezing dry powder that is ground into again by the composition of raw materials of following weight portion: lycopodium calvatum 10-20, frangipanis 8-20, Radix Glycyrrhizae 3-10, seed of Chinese dodder 5-10, Poria cocos 10-20, tuber of dwarf lilyturf 5-10, rush 3-5, dark plum 3-10.
Preparation method is with embodiment 1.

Claims (2)

1. a premixed powder of preventing and treating hyperglycaemia, it is characterized in that by preparing burden and form by weight percentage below, comprise that 10-20% lycopodium calvatum liquid extract dry powder, 1-5% wheat gluten, the xylitol of 4-10%, the bread flour improver of the refined salt of 0.5-3%, 0.01-1%, flour add to very; Described lycopodium calvatum liquid extract dry powder is made after liquid extract the freezing dry powder that is ground into again by the composition of raw materials of following weight portion: lycopodium calvatum 10-20, frangipanis 8-20, Radix Glycyrrhizae 3-10, seed of Chinese dodder 5-10, Poria cocos 10-20, tuber of dwarf lilyturf 5-10.
2. a premixed powder of preventing and treating hyperglycaemia, it is characterized in that by preparing burden and form by weight percentage below, comprise that 10-20% lycopodium calvatum liquid extract dry powder, 1-5% wheat gluten, the xylitol of 4-10%, the bread flour improver of the refined salt of 0.5-3%, 0.01-1%, flour add to very; Described lycopodium calvatum liquid extract dry powder is made after liquid extract the freezing dry powder that is ground into again by the composition of raw materials of following weight portion: lycopodium calvatum 10-20, frangipanis 8-20, Radix Glycyrrhizae 3-10, seed of Chinese dodder 5-10, Poria cocos 10-20, tuber of dwarf lilyturf 5-10, rush 3-5, dark plum 3-10.
CN201410179948.8A 2014-04-30 2014-04-30 Premixed powder for preventing and treating hyperglycemia Pending CN103918740A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104542806A (en) * 2015-01-05 2015-04-29 山东蜜福堂食品有限公司 Sucrose-free cake premixed flour

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1620874A (en) * 2003-11-28 2005-06-01 深圳市海川实业股份有限公司 Prestirred bread flours with healthcare function
CN102726473A (en) * 2012-07-18 2012-10-17 罗晓枚 Selfheal bread premixed powder
CN102940269A (en) * 2012-11-29 2013-02-27 董燕花 Health care frog sausage
CN102940270A (en) * 2012-11-29 2013-02-27 蒋科罡 Pork sausage
CN102940268A (en) * 2012-11-29 2013-02-27 陈花娇 Chicken sausage
CN102960403A (en) * 2012-11-29 2013-03-13 仲珉 Health care cake
CN103355686A (en) * 2013-08-09 2013-10-23 王毓 Fat-reducing goose meat sausage

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1620874A (en) * 2003-11-28 2005-06-01 深圳市海川实业股份有限公司 Prestirred bread flours with healthcare function
CN102726473A (en) * 2012-07-18 2012-10-17 罗晓枚 Selfheal bread premixed powder
CN102940269A (en) * 2012-11-29 2013-02-27 董燕花 Health care frog sausage
CN102940270A (en) * 2012-11-29 2013-02-27 蒋科罡 Pork sausage
CN102940268A (en) * 2012-11-29 2013-02-27 陈花娇 Chicken sausage
CN102960403A (en) * 2012-11-29 2013-03-13 仲珉 Health care cake
CN103355686A (en) * 2013-08-09 2013-10-23 王毓 Fat-reducing goose meat sausage

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104542806A (en) * 2015-01-05 2015-04-29 山东蜜福堂食品有限公司 Sucrose-free cake premixed flour

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