CN103829999A - Liquid nitrogen air minimally invasive cold knife cold and heat source system - Google Patents
Liquid nitrogen air minimally invasive cold knife cold and heat source system Download PDFInfo
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- CN103829999A CN103829999A CN201410103130.8A CN201410103130A CN103829999A CN 103829999 A CN103829999 A CN 103829999A CN 201410103130 A CN201410103130 A CN 201410103130A CN 103829999 A CN103829999 A CN 103829999A
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Abstract
The invention relates to a liquid nitrogen air minimally invasive cold knife cold and heat source system, and belongs to the field of medical equipment. The system comprises a liquid nitrogen suction pipe (1), liquid nitrogen (2), a liquid nitrogen container (3), a liquid nitrogen container air pressurization valve (4), an air pipe (5), a hot air pipe (6), a wet air valve (7), a by-pass valve (8), a dry air valve (9), an electric heater (10), a resistance heating wire (11), a liquid nitrogen valve (12), a liquid nitrogen supply pipe (13), a dry air pipe (14), a dry hot air valve (15), a blowoff valve (16), a hot air regeneration valve (17), an air drying tank (18), a wet air ejection ring (19), a moisture input pipe (20), drying agents (21), an air compressor (22), a pressure air pipe (23), a cold and heat source communication valve (24) and a hot air supply pipe (25). Accordingly, what is only needed is to conduct filling with the liquid nitrogen and the drying agents and shut down the corresponding valves, the resistance heating wire and the air compressor, the liquid nitrogen at the temperature of 196 DEG C below zero can be sent to nidus so that the nidus can be frozen, and then hot air at the temperature of 40 DEG C can be sent out, so that focus tissue is rapidly reheated. Thus, the steps are repeated for several times, and all nidus cells can be ruptured and necrotic.
Description
Technical field:
Title of the present invention is liquid nitrogen air Wicresoft cryoprobe cold and heat source system, belongs to medical instruments field.It comprises liquid nitrogen suction pipe (1), liquid nitrogen (2), liquid nitrogen container (3), liquid nitrogen container air pressurized valve (4), air hose (5), warm-air pipe (6), humid air valve (7), bypass valve (8), dry air valve (9), electric heater (10), resistance heating wire (11), liquid nitrogen valve (12), for liquid nitrogen pipe (13), dry air pipe (14), heated drying air valve (15), exhaust-valve (16), regenerated with hot air valve (18), air drying tank (19), humid air ejection ring (20), dampness input pipe (21), desiccant (22), air compressor (23), Cooling and Heat Source communication valve (24), heat supply airduct (25).Liquid nitrogen air Wicresoft cryoprobe cold and heat source system only need be closed down corresponding valve and resistance heating wire and air compressor and just can be sent to cutter head the hot-air that the low-temperature receiver of-196 ℃ makes focus freeze to send again subsequently 40 ℃ and make the rapid rewarming of lesion tissue, repeats so just can make several times focus cell all dead.
Background technology:
A kind of Novel ultralow-temperature of in October, 1998 U.S. Endocare Developed is got involved cold and hot ablation therapeutic equipment: Crycare minimally invasive surgery system-argon helium knife (www.cryocare.com.cn), and ratify by U.S. FDA, after IEC, EMC and the CE of European Union authentication, enter medical market, just install and use in hospital from all parts of the world very soon.Its invention is the last word of freezing thermal therapeutical technical development, not only inheritance and development ultra low temperature therapeutical basis and the clinical research achievement learned, and released new ideas and the new technique of refrigeration.Although this minimally invasive surgery system-argon helium knife furuncle is imitated, cost of equipment costliness, and the volume mass of focus is had to certain requirement, can not effectively excise larger tumor, thereby limit applying of this technology.
Summary of the invention:
For making up the deficiency of existing above-mentioned technology, the present invention can provide a kind of liquid nitrogen air Wicresoft cryoprobe cold and heat source system, it comprises liquid nitrogen suction pipe (1), liquid nitrogen (2), liquid nitrogen container (3), liquid nitrogen container air pressurized valve (4), air hose (5), warm-air pipe (6), humid air valve (7), bypass valve (8), dry air valve (9), electric heater (10), resistance heating wire (11), liquid nitrogen valve (12), for liquid nitrogen pipe (13), dry air pipe (14), heated drying air valve (15), exhaust-valve (16), regenerated with hot air valve (17), air drying tank (18), humid air ejection ring (19), dampness input pipe (20), desiccant (21), air compressor (22), pressure air pipe (23), Cooling and Heat Source communication valve (24), heat supply airduct (25).In liquid nitrogen container (3), have liquid nitrogen (2), one end of liquid nitrogen suction pipe (1) is submerged in liquid nitrogen (2), the entrance UNICOM of the other end of liquid nitrogen suction pipe (1) and liquid nitrogen valve (12) is fixed, the outlet of the outlet of liquid nitrogen valve (12) and Cooling and Heat Source communication valve (24) and fixed for the entrance point UNICOM of liquid nitrogen pipe (13); The inlet end UNICOM of the entrance of the entrance of Cooling and Heat Source communication valve (24) and heated drying air valve (15) and heat supply airduct (25) is fixed; The end of pressure air pipe (23) inserts liquid nitrogen (2) the top air layer of liquid nitrogen container (3), whole liquid nitrogen container (3) is all in sealing state, and the port of export UNICOM of the other end of pressure air pipe (23) and liquid nitrogen container air pressurized valve (4) is fixed; The port of export UNICOM of the entrance of air hose (5) and air compressor (22) is fixed, the entrance UNICOM of the entrance of the outlet of air hose (5) and liquid nitrogen container air pressurized valve (4), the entrance of humid air valve (7) and bypass valve (8) is fixed, and the inlet end of the outlet of humid air valve (7) and dampness input pipe (20) and the port of export UNICOM of warm-air pipe (6) are fixed; The outlet UNICOM of the entrance of warm-air pipe (6) and regenerated with hot air valve (17) is fixed, and the entrance of the entrance of regenerated with hot air valve (17) and heated drying air valve (15) and the outlet UNICOM of electric heater (10) are fixed; The outlet of the entrance of electric heater (10) and bypass valve (8) and the outlet UNICOM of dry air valve (9) fixed, the exhaust end of the entrance of dry air valve (9) and dry air pipe (14) and the entrance UNICOM of exhaust-valve (16) are fixed; The inlet end of dry air pipe (14) stretches into the upper space of air drying tank (18), the desiccant (21) of tank high 3/4 is housed in air drying tank (18), the outlet UNICOM of the outlet of the upper end of dampness input pipe (20) and warm-air pipe (6) and humid air valve (7) is fixed, and the lower end of dampness input pipe (20) is through desiccant (21) layer fixed with humid air ejection ring (19) UNICOM that is embedded in desiccant (21) bottom.
Accompanying drawing explanation:
Fig. 1. be the cryoprobe cold and heat source system figure of liquid nitrogen air Wicresoft.
Wherein: 1--liquid nitrogen suction pipe; 2--liquid nitrogen; 3--liquid nitrogen container; 4--liquid nitrogen container air pressurized valve; 5--air hose; 6--warm-air pipe; 7--humid air valve; 8--bypass valve; 9--dry air valve; 10--electric heater; 11--resistance heating wire; 12--liquid nitrogen valve; 13--is for liquid nitrogen pipe; 14--dry air pipe; 15--heated drying air valve; 16--exhaust-valve; 17--regenerated with hot air valve; 18--air drying tank; 19--humid air ejection ring; 20--dampness input pipe; 21--desiccant; 22--air compressor; 23 1 pressure air pipes.
Liquid nitrogen air Wicresoft cryoprobe cold and heat source system bind mode is as follows:
In liquid nitrogen container (3), have liquid nitrogen (2), one end of liquid nitrogen suction pipe (1) is submerged in liquid nitrogen (2), the entrance UNICOM of the other end of liquid nitrogen suction pipe (1) and liquid nitrogen valve (12) is fixed, the outlet of the outlet of liquid nitrogen valve (12) and Cooling and Heat Source communication valve (24) and fixed for the entrance point UNICOM of liquid nitrogen pipe (13); The inlet end UNICOM of the entrance of the entrance of Cooling and Heat Source communication valve (24) and heated drying air valve (15) and heat supply airduct (25) is fixed; The end of pressure air pipe (23) inserts liquid nitrogen (2) the top air layer of liquid nitrogen container (3), whole liquid nitrogen container (3) is all in sealing state, and the port of export UNICOM of the other end of pressure air pipe (23) and liquid nitrogen container air pressurized valve (4) is fixed; The port of export UNICOM of the entrance of air hose (5) and air compressor (22) is fixed, the entrance UNICOM of the entrance of the outlet of air hose (5) and liquid nitrogen container air pressurized valve (4), the entrance of humid air valve (7) and bypass valve (8) is fixed, and the inlet end of the outlet of humid air valve (7) and dampness input pipe (20) and the port of export UNICOM of warm-air pipe (6) are fixed; The outlet UNICOM of the entrance of warm-air pipe (6) and regenerated with hot air valve (17) is fixed, and the entrance of the entrance of regenerated with hot air valve (17) and heated drying air valve (15) and the outlet UNICOM of electric heater (10) are fixed; The outlet of the entrance of electric heater (10) and bypass valve (8) and the outlet UNICOM of dry air valve (9) fixed, the exhaust end of the entrance of dry air valve (9) and dry air pipe (14) and the entrance UNICOM of exhaust-valve (16) are fixed; The inlet end of dry air pipe (14) stretches into the upper space of air drying tank (18), the desiccant (21) of tank high 3/4 is housed in air drying tank (18), the outlet UNICOM of the outlet of the upper end of dampness input pipe (20) and warm-air pipe (6) and humid air valve (7) is fixed, and the lower end of dampness input pipe (20) is through desiccant (21) layer fixed with humid air ejection ring (19) UNICOM that is embedded in desiccant (21) bottom.
The specific embodiment:
Fig. 1 is also the liquid nitrogen air Wicresoft cryoprobe cold and heat source system of doing living animal experiment.
The preparatory stage of liquid nitrogen air Wicresoft cryoprobe cold and heat source system is to put into 3kg desiccant in air drying tank, to 5 liters of liquid nitrogen of filling in liquid nitrogen container.First make focus freezing, needing to open compressor boosts to after 0.3MPa liquid nitrogen container, open liquid nitrogen valve, liquid nitrogen just can from liquid nitrogen container through liquid nitrogen suction pipe flow through liquid nitrogen valve and along for liquid nitrogen pipe flow to cryoprobe cutter head, liquid nitrogen evaporates and makes focus be chilled to-174 ℃ in cutter head, and the nitrogen that liquid nitrogen vaporization forms is discharged from handle of a knife.Close again liquid nitrogen container air pressurized valve and liquid nitrogen valve bypass valve, open humid air valve, dry air valve, Cooling and Heat Source communication valve, electric heater and heated drying air valve, the heated drying air of 40 ℃ flows out after entering after air drying tank dehumidification that electric heater is heated and being warming up to 40 ℃ and flows to cutter head from air compressor, make the rapid rewarming of lesion tissue, two 3 lesion tissue cells like this will make cell wall all break and death.After repeatedly using, desiccant, because absorption moisture content too much lost efficacy, just needs thermal regeneration.Now open air compressor, bypass valve, electric heater, regenerated with hot air valve, exhaust-valve, close humid air valve, Cooling and Heat Source communication valve, liquid nitrogen container air pressurized valve and heated drying air valve, air just flows out after bypass valve enters electric heater to be heated to 110 ℃ and delivers to humid air ejection ring through regenerated with hot air valve, dampness input pipe from air compressor, and spray into from here desiccant layer, desiccant is heated up after dehydration, and air is discharged into atmosphere through exhaust-valve.Conventionally regeneration just can make desiccant restore funcitons in 45 minutes and reusable.
Claims (1)
1. a liquid nitrogen air Wicresoft cryoprobe cold and heat source system, it comprises liquid nitrogen suction pipe (1), liquid nitrogen (2), liquid nitrogen container (3), liquid nitrogen container air pressurized valve (4), air hose (5), warm-air pipe (6), humid air valve (7), bypass valve (8), dry air valve (9), electric heater (10), resistance heating wire (11), liquid nitrogen valve (12), for liquid nitrogen pipe (13), dry air pipe (14), heated drying air valve (15), exhaust-valve (16), regenerated with hot air valve (17), air drying tank (18), humid air ejection ring (19), dampness input pipe (20), desiccant (21), air compressor (22), pressure air pipe (23), Cooling and Heat Source communication valve (24), heat supply airduct (25), it is characterized in that having in liquid nitrogen container (3) liquid nitrogen (2), one end of liquid nitrogen suction pipe (1) is submerged in liquid nitrogen (2), the entrance UNICOM of the other end of liquid nitrogen suction pipe (1) and liquid nitrogen valve (12) is fixed, the outlet of the outlet of liquid nitrogen valve (12) and Cooling and Heat Source communication valve (24) and fixed for the entrance point UNICOM of liquid nitrogen pipe (13), the inlet end UNICOM of the outlet of the entrance of Cooling and Heat Source communication valve (24) and heated drying air valve (15) and heat supply airduct (25) is fixed, the end of pressure air pipe (23) inserts liquid nitrogen (2) the top air layer of liquid nitrogen container (3), whole liquid nitrogen container (3) is all in sealing state, and the port of export UNICOM of the other end of pressure air pipe (23) and liquid nitrogen container air pressurized valve (4) is fixed, the port of export UNICOM of the entrance of air hose (5) and air compressor (22) is fixed, the entrance UNICOM of the entrance of the outlet of air hose (5) and liquid nitrogen container air pressurized valve (4), the entrance of humid air valve (7) and bypass valve (8) is fixed, and the inlet end of the outlet of humid air valve (7) and dampness input pipe (20) and the port of export UNICOM of warm-air pipe (6) are fixed, the outlet UNICOM of the entrance of warm-air pipe (6) and regenerated with hot air valve (17) is fixed, and the entrance of the entrance of regenerated with hot air valve (17) and heated drying air valve (15) and the outlet UNICOM of electric heater (10) are fixed, the outlet of the entrance of electric heater (10) and bypass valve (8) and the outlet UNICOM of dry air valve (9) fixed, the exhaust end of the entrance of dry air valve (9) and dry air pipe (14) and the entrance UNICOM of exhaust-valve (16) are fixed, the inlet end of dry air pipe (14) stretches into the upper space of air drying tank (18), the desiccant (21) of tank high 3/4 is housed in air drying tank (18), the outlet UNICOM of the outlet of the upper end of dampness input pipe (20) and warm-air pipe (6) and humid air valve (7) is fixed, and the lower end of dampness input pipe (20) is through desiccant (21) layer fixed with humid air ejection ring (19) UNICOM that is embedded in desiccant (21) bottom.
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| CN201410103130.8A CN103829999A (en) | 2014-03-12 | 2014-03-12 | Liquid nitrogen air minimally invasive cold knife cold and heat source system |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107205766A (en) * | 2014-11-13 | 2017-09-26 | 艾达吉欧医疗公司 | The Cryoablation system and correlation technique of pressure controlling |
| CN107576124A (en) * | 2017-08-16 | 2018-01-12 | 中国科学院理化技术研究所 | A kind of low-temperature circulating system |
| CN111337536A (en) * | 2020-04-13 | 2020-06-26 | 西安交通大学 | Liquid drop stream radiation heat exchange experimental device and method |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107205766A (en) * | 2014-11-13 | 2017-09-26 | 艾达吉欧医疗公司 | The Cryoablation system and correlation technique of pressure controlling |
| CN107205766B (en) * | 2014-11-13 | 2020-04-14 | 艾达吉欧医疗公司 | Pressure regulated cryoablation system and related methods |
| CN107576124A (en) * | 2017-08-16 | 2018-01-12 | 中国科学院理化技术研究所 | A kind of low-temperature circulating system |
| CN111337536A (en) * | 2020-04-13 | 2020-06-26 | 西安交通大学 | Liquid drop stream radiation heat exchange experimental device and method |
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