CN103751071A - Non-fragrance and non-trace type skin maintaining agent for men and preparation method thereof - Google Patents

Non-fragrance and non-trace type skin maintaining agent for men and preparation method thereof Download PDF

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CN103751071A
CN103751071A CN201410048658.XA CN201410048658A CN103751071A CN 103751071 A CN103751071 A CN 103751071A CN 201410048658 A CN201410048658 A CN 201410048658A CN 103751071 A CN103751071 A CN 103751071A
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weight portion
skin
men
coenzyme
hyaluronic acid
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CN103751071B (en
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孙媛
赵毅
刘波
汤秀梅
石浩
田霞
谢晓宇
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Yunnan Pharmaceutical Institute
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Abstract

The invention relates to a non-fragrance and non-trace type skin maintaining agent special for men and a preparation method thereof. The skin maintaining agent is prepared by mixing olive oil, grape seed oil, coenzyme Q10, a wolfberry extract, hyaluronic acid, glycerinum, polyethylene glycol, carbomer 980 and purified water according to a certain proportion. The skin maintaining agent comprises the following components in parts by weight: 0.005 to 20 parts of olive oil, 0.005 to 20 parts of grape seed oil, 0.001 to 1 part of coenzyme Q10, 0.01 to 10 parts of wolfberry extract, 0.01 to 10 parts of hyaluronic acid, a small amount of glycerinum, polyethylene glycol 400, carbomer 980, and the balance of purified water. The skin maintaining agent can be directly smeared on the face, hands or required parts, thereby realizing the moisturizing, aging resistance and oxidizing resistance, and replenishing the nutrition required by the body skin.

Description

A kind of zero fragrant seamless skin maintenance agent for men only and preparation method thereof
Technical field
The present invention relates to a kind of skin maintenance agent for men only, specifically there are beauty and make-up articles for use for moisturizing, defying age and antioxidation, can be used for beautifying skin, reparation, moisten, desalinate zero fragrant seamless skin maintenance agent for men only (external) of microgroove, speckle and preparation method thereof.
Background technology
In the male of state-owned skin protection custom fewer, most of male in the past only when washing one's face occasional use fancy soap.Now, along with the raising year by year of people's living standard, the quickening of modern life rhythm and the increase of survival pressure, add the environmental pollution of modern metropolitan cities and day by day severe natural climate, cause increasing people to occur skin problem, make skin nursing seem more and more important.Men also start to have recognized gradually the importance of skin nursing, and increasing consumer starts to focus on " face-saving project ".Meanwhile, man skin possesses following characteristics: 1, male's skin ratio is easier to hydropenia.Male's skin is easier to water loss compared with women's ratio, also drier decortication.Therefore, the moisturizing of man's skin care item is top priority; 2, in man's body, Serum Testosterone Levels is much higher than women.Androgen can promote sebaceous hyperplasia hypertrophy, stimulate fat secretion to cause facial oil too much, so 80% male is the skin of oiliness or the inclined to one side oiliness of Combination, easily the pH value of fuel-displaced male's skin is also lower, about 4.5-6, be easy to grow various skin problems, as: hypersteatosis can make pore become thick, dust and antibacterial in the easy absorbed air of oils and fats, cause the chance of inflammation and infection to increase, so more easily there is the skin problems such as the colour of skin is obscure, corse sweat pore, acne.Therefore, man skin need to supplement more juicy to regulate oil-water balance, and this just has requirements at the higher level to skin care item moisture-keeping function; 3, male's skin is than thick 40% left and right of women, and therefore, man's skin care item rely at the osmotic effect of skin more to nutritional labeling; 4, male's outdoor activities are many, make male's skin elasticity scatter and disappear speed far away higher than women, and this just means, once man produces wrinkle, and will be more more obvious and dark than Ms.Therefore, the antioxidation in man's skin protection and defying age are also very important.In addition, Chinese male is just focused on own external image since ancient times very much, and the product that has obvious fragrance is not admitted by most of male consumer, and male consumer can not spend the more time as women, energy is in skin protection maintenance.Eventually the above, do not have fragrance, the man skin maintenance items that has the multi-efficiencies such as moisturizing, antioxidation, slow down aging concurrently and can be beneficial to skin osmotic absorption is market in urgent need and existing product cannot meet simultaneously far away.
Summary of the invention
Object of the present invention aims to provide a kind of man skin maintenance agent with moisturizing, defying age and antioxidation and preparation method thereof.
The present invention reaches above-mentioned object by following technical scheme.It is characterized in that adding by weight following raw material: the coenzyme Q10 of the olive oil of 0.005-20 weight portion, the Oleum Vitis viniferae of 0.005-20 weight portion, 0.001-1 weight portion, the wolfberry fruit extract of 0.01-10 weight portion, the hyaluronic acid of 0.01-10 weight portion, remainder is substrate.
The preparation method of the man skin maintenance agent in the present invention is: (1) is often got 1 weight portion by Fructus Lycii medical material and added 5-10 water doubly, decocts two to three mixing, filters, and filtrate is concentrated into the l/3 of original volume, places, and filters, and lyophilization obtains Chinese medicine extract; (2) coenzyme Q10 of 0.001-1 weight portion is dissolved in the Oleum Vitis viniferae of 0.005-20 weight portion and is prepared into mixing oily solution, standby; (3) hyaluronic acid of 0.01-10 weight portion is dissolved in the water, is mixed with the aqueous solution of 0.05-10%, standby; (4) Carbopol, glycerol, purified water are mixed to swelling placement and spend the night, triethanolamine regulates pH value to neutral, standby as substrate; (5) wolfberry fruit extract of the hyaluronic acid of 0.01-10 weight portion (melt into aqueous solution), 0.01-10 weight portion is first added to mix homogeneously in above-mentioned substrate, add again the olive oil of 0.005-20 weight portion, the coenzyme Q10 of 0.001-1 weight portion to be dissolved in oil solution and the PEG400 mixed liquor of the Oleum Vitis viniferae of 0.005-20 weight portion, stir, subpackage.
The present invention has efficient moisture-retention, improves the function of skin water conservation, thereby regulates the oil-water balance of man skin, improves the state of the undue secretion of oils and fats, prevents skin because of hydropenia accelerated ageing and produces various skin infections; Metabolism in antioxidation, defying age, promotion body, prevent organism aging process, prevent the injury of reactive oxygen free radical to skin, give skin cell energy, adjust the skin regeneration period, improve because free radical generates caused xerosis cutis, mottle, wrinkle, the skin aging problem such as lax, coarse, responsive; Strengthen and promote skin blood capillary blood circulation, protection skin collagen protein and elastic fiber, prevent injury, the protection of ultraviolet to skin and strengthen skin histology resistance, the healthy glow of the skin that rejuvenates; The present invention makes it have good absorbing power to the high penetrating power of skin, prevents skin-nourishing ingredients from lossing, and to skin gentleness, non-stimulated, all kinds skin all can be used.
Through studying for a long period of time and testing discovery, skin divides epidermis, corium and subcutaneous fat.The outermost layer of epidermis is horny layer, and due to water suction, the barrier function of horny layer itself, and in horny layer, contained nature moisturizing factor is the effect of amino acids, lactate and saccharide etc., makes horny layer keep certain water content, maintains the moistening of skin.And the outward appearance of skin is relevant with cuticular moisture, normal keratodermatitis contains the moisture of 10%-30% conventionally, to maintain softness and the elasticity of skin.Along with the variation of the factors such as age, weather, keratodermatitis moisture also can fluctuate thereupon, and when the moisture of keratodermatitis is lower than 10% time, skin just there will be dry, tight, coarse and desquamation etc.Male's skin is easier to water loss compared with women's ratio, also drier decortication.Dry and old and feeble male's skin problem of association simultaneously often, dermal collagen fiber and elastic fiber reduce, metabolism is slack-off, moisture of skin and subcutaneous fat reduces, cutaneous circulation is slack-off, and VAR is poor, shaving causes the malnutrition of removing termly the oils and fats of skin epidermis and producing trickle scytitis, skin, bad living habit all can cause the presenility of crossing of man skin.The present invention is directed to the physiological characteristics of skin, adopt by weight following natural component: the coenzyme Q10 of the olive oil of 0.005-20 weight portion, the Oleum Vitis viniferae of 0.005-20 weight portion, 0.001-1 weight portion, the wolfberry fruit extract of 0.01-10 weight portion, the hyaluronic acid of 0.01-10 weight portion, reach moisturizing, defying age and antioxidative effect to man skin.
In the natural component of above-mentioned effect: hyaluronic acid is the natural high moisturizing material self containing in human body.It is one of proper constituent in human body, and according to estimates, a human body contains approximately 15 grams of hyaluronic acids.The most important functions that it is brought into play is exactly water retention.Exactly because the perfect state that baby's skin presents contains abundant hyaluronic acid, softness is flexible again.The present invention is that skin supplements appropriate hyaluronic acid, not only can help skin in body and moisture that skin surface is inhaled in a large number (hyaluronic acid of 1 molecule approximately can in conjunction with the hydrone of 600 times), can also strengthen the long water holding capacity of skin.When hyaluronic acid is when skin substrate is full of moisture, elastic fibers and collagen protein are in the environment that is full of moisture, skin wrinkle will calm down unconsciously gradually.Meanwhile, the present invention has selected high water type substrate: Carbopol and glycerol, further improved moistening effect.
Fructus Lycii have the laudatory title of " Bao Shu ", " loblolly tree ".The traditional Chinese medical science thinks, Fructus Lycii sweet in the mouth is flat, has the effects such as the kidney invigorating, YIN nourishing, nourishing the liver, improving eyesight, QI invigorating.Ancients say: " Fructus Lycii can be kept youth beauty here." < < Compendium of Materia Medica > > records: steep in wine with Fructus Lycii, long-term drink can be in case preserve youthful looks always, alive for evermore.Fructus Lycii is quite extensive already as its application of medicine.Can be used as the functions such as immunomodulating, antioxidation, defying age, skin care, brain-strengthening, toxin expelling, Antiradiation injury but knows little about it.Fructus Lycii can improve skin and absorb the ability that oxygen divides, and the running comprehensively of Fructus Lycii interior contained various vitamin, essential amino acid and linoleic acid, more can promote the metabolism in body, prevents organism aging process.Fructus Lycii cures mainly pathogen in the five internal organs, hankers quenching one's thirst.Therefore can mend vital essence deficiency, skin care, bleaches skin, makes us long-lived.In the present invention, adopt Fructus Lycii to prepare wolfberry fruit extract, its preparation technology is: Fructus Lycii medical material is respectively got to 1 weight portion and add 5-10 water doubly, decoct two to three mixing, filter, filtrate is concentrated into the l/3 of original volume, places, and filters, and lyophilization obtains Chinese medicine extract.
Coenzyme Q10 is also the defying age material of human body self, from nineteen fifty-seven, finds, is just referred to as " source of the health of cell ".It is the power resources of manufacturing collagen protein, hyaluronic acid, cell tissue liquid etc., and these materials make our fragile muscle and skin plump in vain.It is more than 10 times that in our skin epidermis cell, the content of coenzyme Q10 is hypodermal cell, but because the content of coenzyme Q10 can successively decrease with advancing age, ultraviolet or stress etc. also can make the coenzyme Q10 containing in epidermis reduce, it is weak that skin metabolism will become, and skin elastic force declines, moistens degree deficiency.The present invention adds in substrate after adopting Oleum Vitis viniferae to dissolve coenzyme Q10; can improve significantly the addition of coenzyme Q10; suppress better lipid peroxidation; reduce the generation of free radical; protection SOD active center and structure thereof are avoided Free radicals injury; improve the enzymatic activitys such as the interior SOD of body; the apoptosis of inhibited oxidation stress induction; thereby antioxidation and slow down aging more significantly; coenzyme Q10 Oleum Vitis viniferae solution has improved the compliance of skin; skin maintenance agent milder prepared by the present invention, non-stimulated.--by Jiajiale, purchase the tissue issue of health product store herein
Oleum Vitis viniferae has two kinds of very important elements: linoleic acid and proanthocyanidin.Linoleic acid can be resisted free radical, and aging resistance helps to absorb vitamin C and E, and the elasticity of strengthening blood circulation, reduces ultraviolet injury, and the collagen protein in protection skin, improves venous engorgement and edema, prevention melanin deposition.Linoleic acid content reaches more than 70%.Linoleic acid be needed by human and for human body can not be synthetic fatty acid.Proanthocyanidin (OPC) has superpower oxidation resistance, is 50 times of vitamin e, energy delaying aging, and prevention of arterial hardens, and also has the title of skin vitamin, is 20 times of vitamin C, and phenol anthocyanidin wherein, according to fat-soluble and water miscible speciality, has whitening function.Proanthocyanidin also has protection blood vessel elasticity, and protection skin avoids ultraviolet afflicting with great suffering torment, and the destruction of prevention collagen fiber and elastic fiber, makes skin keep due elasticity and tension force, avoids skin sagging and wrinkle to produce.The present invention adopts Oleum Vitis viniferae to improve the microvascular blood circulation of skin, removes oxygen-derived free radicals, makes regenerative cell and shielded epidermis cell moisture full, reaches the object of antioxidation, slow down aging and moisturizing simultaneously.Meanwhile, the present invention, by research, combines and uses the skin affinity of olive oil and the strong penetration of skin of Oleum Vitis viniferae, make zero fragrant seamless skin maintenance agent for men only of preparation be more applicable for man skin, salubrious non-greasy, is very easily absorbed by the skin, and any skin quality is all suitable for.
The present invention stimulates with reference to < < safety evaluation of cosmetics program and method > >, SFDA. Chinese medicine, natural drug
Property and hemolytic investigative technique guideline [Z] GPT4-1 related content:
Adopt consubstantiality Self-control method that 8 rabbit are divided into two groups of A, B at random by sex and body weight, i.e. zero fragrant seamless man skin maintenance agent sample intact skin group (being called for short A group), zero fragrant seamless man skin maintenance agent sample damaged skin group (being called for short B group), every group 4, male and female half and half, five of the skin of back unhairing of every animal: top, left portion, right middle, lower left quarter, right lower quadrant.Press following program administration:
A group and B treated animal are coated with 0.50ml sodium chloride injection on the top, unhairing district of intact skin and damaged skin respectively, left portion, right middle are coated with the fragrant seamless man skin maintenance agent blank of 0.50g zero, and lower left quarter, right lower quadrant are coated with the fragrant seamless man skin maintenance agent sample of 0.50g zero.
All animal successive administrations 14 days, observe medicine-feeding part skin symptom scoring (with reference to table 1, table 2) every day.All animals are put to death in drug withdrawal after 3 days.
table 1 skin irritation reaction standards of grading
Figure 201410048658X100002DEST_PATH_IMAGE001
table 2 skin irritation intensity evaluation standard
Score value Evaluate
0~0.49 Nonirritant
0.5~2.99 Slight zest
3.0~5.99 Moderate zest
6.0~8.00 Severe zest
Result is as follows:
(1) overview result: duration of test is not observed animal whole body toxicity.
(2) medicine-feeding part observed result:
1. during negative control Skin observing, do not show any abnormalities.
2. zero fragrant seamless man skin maintenance agent sample intact skin and damaged skin: during sample blank and sample administration all animals all without or only have light erythema to occur, but after drug withdrawal, all recover normal; Wherein damaged skin treated animal stimulus intensity is marked a little more than intact skin group.
(3) scoring of skin irritation intensity and evaluation result: in Table 3.
1. negative control is evaluated mean scores to the stimulus intensity of complete and damaged skin and is 0, nonirritant.
2. zero fragrant seamless man skin maintenance agent sample intact skin and damaged skin: sample blank and sample are evaluated mean scores to intact skin stimulus intensity and be respectively 0.47,0.44,0.41 and 0.43, damaged skin stimulus intensity is evaluated to mean scores and be respectively 0.48,0.49,0.50 and 0.53, therefore can think that sample 1 blank and sample 1, to intact skin nonirritant, have slight zest to damaged skin.
table 3 four samples are to skin irritation intensity evaluation mean scores and evaluation result
Figure 201410048658X100002DEST_PATH_IMAGE002
Conclusion: under this experiment condition, continuously skin applies zero fragrant seamless man skin maintenance agent sample and blank product 14 days thereof, drug withdrawal recovers to observe 3 days, sample has slight zest to damaged skin, and after sample drug withdrawal, animals administer position finding symptom is all recovered completely.During administration, do not observe experimental animal whole body toxicity.Prompting sample to intact skin without skin irritation.
In addition, also observed 400 routine people's result of use, 400 examples are Chinese Male Adults, age 25-65 year, and all free from infection histories, concrete result of use is as shown in table 4-5.
the satisfaction of table 4 400 example application this product
Number Sex Average access times Very satisfied Satisfied Dissatisfied
400 Man 20 376 24 /
the routine user applicable cases of table 5 400
Number of cases Skin talent for swimming is improved The light speckle of wrinkle removal Improve skin sensitivity
Significant figure 376 340 320
Invalid number 24 60 80
Effective percentage (%) 94% 85% 80%
the specific embodiment:
Embodiment 1:
prescription:olive oil: 0.03 weight portion; Oleum Vitis viniferae: 0.12 weight portion; Coenzyme Q10: 0.002 weight portion; Wolfberry fruit extract: 0.04 weight portion; Hyaluronic acid: 1.0 weight portions; Remainder is substrate.
method for making:(1) Fructus Lycii medical material is got to the water that 1 weight portion adds 8 times, decoct three mixing, filter, filtrate is concentrated into the l/3 of original volume, places, and filters, and lyophilization obtains Chinese medicine extract; (2) coenzyme Q10 of 0.002 weight portion is dissolved in the Oleum Vitis viniferae of 0.12 weight portion and is prepared into mixing oily solution, standby; (3) hyaluronic acid of 1.0 weight portions is dissolved in the water, is mixed with 2% aqueous solution, standby; (4) Carbopol (1.5 weight portion), glycerol (6 weight portion), purified water (90.5 weight portion) are mixed to swelling placement and spend the night, triethanolamine (2 weight portion) regulates pH value to neutral, standby as substrate; (5) wolfberry fruit extract of the hyaluronic acid of 1.0 weight portions (having made 2% aqueous solution), 0.04 weight portion is first added to mix homogeneously in the substrate that above-mentioned weight portion summation is 49.208, add again the olive oil of 0.03 weight portion, the coenzyme Q10 of 0.002 weight portion to be dissolved in oil solution and PEG400 (0.6 weight portion) mixed liquor of the Oleum Vitis viniferae of 0.12 weight portion, stir, subpackage.
purposes:this zero fragrant seamless skin maintenance agent for men only, is applicable to various skin quality, can directly be applied in face, hand or other positions needing, can moisturizing, defying age, antioxidation, supplement the required all kinds of nutrition of human body skin.
  
Embodiment 2:
prescription:olive oil: 0.01 weight portion; Oleum Vitis viniferae: 20 weight portions; Coenzyme Q10: 0.8 weight portion; Wolfberry fruit extract: 10 weight portions; Hyaluronic acid: 0.04 weight portion; Remainder is substrate.
method for making:(1) Fructus Lycii medical material is got to the water that 1 weight portion adds 5 times, decoct three mixing, filter, filtrate is concentrated into the l/3 of original volume, places, and filters, and lyophilization obtains Chinese medicine extract; (2) coenzyme Q10 of 0.8 weight portion is dissolved in the Oleum Vitis viniferae of 20 weight portions and is prepared into mixing oily solution, standby; (3) hyaluronic acid of 0.04 weight portion is dissolved in the water, is mixed with 0.1% aqueous solution, standby; (4) Carbopol (1.5 weight portion), glycerol (6 weight portion), purified water (89.5 weight portion) are mixed to swelling placement and spend the night, triethanolamine (3 weight portion) regulates pH value to neutral, standby as substrate; (5) wolfberry fruit extract of the hyaluronic acid of 0.04 weight portion (having made 0.1% aqueous solution), 10 weight portions is first added to mix homogeneously in the substrate that above-mentioned weight portion summation is 19.19, add again the olive oil of 0.01 weight portion, the coenzyme Q10 of 0.8 weight portion to be dissolved in oil solution and PEG400 (10 weight portion) mixed liquor of the Oleum Vitis viniferae of 20 weight portions, stir, subpackage.
purposes:this zero fragrant seamless skin maintenance agent for men only, is applicable to various skin quality, can directly be applied in face, hand or other positions needing, can moisturizing, defying age, antioxidation, supplement the required all kinds of nutrition of human body skin.
  
Embodiment 3:
prescription:olive oil: 0.03 weight portion; Oleum Vitis viniferae: 0.12 weight portion; Coenzyme Q10: 0.0012 weight portion; Wolfberry fruit extract: 1.5 weight portions; Hyaluronic acid: 8 weight portions; Remainder is substrate.
method for making:(1) Fructus Lycii medical material is got to the water that 1 weight portion adds 10 times, decoct twice mixing, filter, filtrate is concentrated into the l/3 of original volume, places, and filters, and lyophilization obtains Chinese medicine extract; (2) coenzyme Q10 of 0.0012 weight portion is dissolved in the Oleum Vitis viniferae of 0.12 weight portion and is prepared into mixing oily solution, standby; (3) hyaluronic acid of 8 weight portions is dissolved in the water, is mixed with 10% aqueous solution, standby; (4) Carbopol (1.5 weight portion), glycerol (6 weight portion), purified water (89.5 weight portion) are mixed to swelling placement and spend the night, triethanolamine (3 weight portion) regulates pH value to neutral, standby as substrate; (5) wolfberry fruit extract of the hyaluronic acid of 8 weight portions (having made 10% aqueous solution), 1.5 weight portions is first added to mix homogeneously in the substrate that above-mentioned weight portion summation is 17.7488, add again the olive oil of 0.03 weight portion, the coenzyme Q10 of 0.0012 weight portion to be dissolved in oil solution and PEG400 (0.6 weight portion) mixed liquor of the Oleum Vitis viniferae of 0.12 weight portion, stir, subpackage.
purposes:this zero fragrant seamless skin maintenance agent for men only, is applicable to various skin quality, can directly be applied in face, hand or other need position, can moisturizing, defying age, antioxidation, supplement the required all kinds of nutrition of human body skin.
  
Embodiment 4:
prescription:olive oil: 16 weight portions; Oleum Vitis viniferae: 0.12 weight portion; Coenzyme Q10: 0.0012 weight portion; Wolfberry fruit extract: 1.5 weight portions; Hyaluronic acid: 0.04 weight portion; Remainder is substrate.
method for making:(1) Fructus Lycii medical material is got to the water that 1 weight portion adds 10 times, decoct twice mixing, filter, filtrate is concentrated into the l/3 of original volume, places, and filters, and lyophilization obtains Chinese medicine extract; (2) coenzyme Q10 of 0.0012 weight portion is dissolved in the Oleum Vitis viniferae of 0.12 weight portion and is prepared into mixing oily solution, standby; (3) hyaluronic acid of 0.04 weight portion is dissolved in the water, is mixed with 1.5% aqueous solution, standby; (4) Acritamer 940 (2.0 weight portion), glycerol (3.0 weight portion), purified water (91.0 weight portion) are mixed to swelling placement and spend the night, triethanolamine (4.0 weight portion) regulates pH value to neutral, standby as substrate; (5) wolfberry fruit extract of the hyaluronic acid of 0.04 weight portion (having made 1.5% aqueous solution), 1.5 weight portions is first added to mix homogeneously in the substrate that above-mentioned weight portion summation is 63.7121, add again the olive oil of 16 weight portions, the coenzyme Q10 of 0.0012 weight portion to be dissolved in oil solution and PEG400 (16 weight portion) mixed liquor of the Oleum Vitis viniferae of 0.12 weight portion, stir, subpackage.
purposes:this zero fragrant seamless skin maintenance agent for men only, is applicable to various skin quality, can directly be applied in face, hand or other positions needing, can moisturizing, defying age, antioxidation, supplement the required all kinds of nutrition of human body skin.

Claims (6)

1. a fragrant seamless skin maintenance agent for men only, it is characterized in that being mixed by a certain percentage by olive oil, Oleum Vitis viniferae, coenzyme Q10, wolfberry fruit extract, hyaluronic acid, glycerol, Polyethylene Glycol, Carbopol, triethanolamine and purified water, it comprises the component of following parts by weight: the coenzyme Q10 of the olive oil of 0.005-20 weight portion, the Oleum Vitis viniferae of 0.005-20 weight portion, 0.001-1 weight portion, the wolfberry fruit extract of 0.01-10 weight portion, the hyaluronic acid of 0.01-10 weight portion, remainder is substrate.
2. according to claim 1 zero fragrant seamless skin maintenance agent for men only, it is characterized in that preparation method is: (1) is often got 1 weight portion by Fructus Lycii medical material and added 5-10 water doubly, decoct two to three mixing, filter, filtrate is concentrated into the l/3 of original volume, place, filter, lyophilization obtains Chinese medicine extract; (2) coenzyme Q10 of 0.001-1 weight portion is dissolved in the Oleum Vitis viniferae of 0.005-20 weight portion and is prepared into mixing oily solution, standby; (3) hyaluronic acid of 0.01-10 weight portion is dissolved in the water, is mixed with the aqueous solution of 0.05-10%, standby; (4) Carbopol, glycerol, purified water are mixed to swelling placement and spend the night, triethanolamine regulates pH value to neutral, standby as substrate; (5) wolfberry fruit extract of the hyaluronic acid of 0.01-10 weight portion (melt into aqueous solution), 0.01-10 weight portion is first added to mix homogeneously in above-mentioned substrate, add again the olive oil of 0.005-20 weight portion, the coenzyme Q10 of 0.001-1 weight portion to be dissolved in oil solution and the PEG400 mixed liquor of the Oleum Vitis viniferae of 0.005-20 weight portion, stir, subpackage.
3. according to the fragrant seamless skin maintenance agent for men only of zero described in claim 1,2, it is characterized in that above-mentioned wolfberry fruit extract is made by following method: Fructus Lycii medical material is often got to 1 weight portion and add 5-10 water doubly, decoct two to three mixing, filter, filtrate is concentrated into the l/3 of original volume, place, filter, lyophilization obtains Chinese medicine extract.
4. according to the fragrant seamless skin maintenance agent for men only of zero described in claim 1,2, it is characterized in that above-mentioned hyaluronic acid need be mixed with the aqueous solution of 0.05-10% by weight percentage.
5. according to the fragrant seamless skin maintenance agent for men only of zero described in claim 1,2, it is characterized in that coenzyme Q10 need first be dissolved in preparation in Oleum Vitis viniferae in the ratio of above-mentioned weight portion and mix oily solution.
6. according to a kind of zero fragrant seamless skin maintenance agent for men only described in claim 1,2, be applicable to various skin quality, can directly be applied in face, hand or other positions needing, can moisturizing, defying age, antioxidation, supplement the required all kinds of nutrition of human body skin.
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CN103169637A (en) * 2013-03-13 2013-06-26 广州中涵生物科技有限公司 Cosmetic preparation for repairing aging rough skin and simultaneously repairing large pores
CN103202928A (en) * 2012-06-15 2013-07-17 广州环亚化妆品科技有限公司 Traditional Chinese medicine composition with anti-aging function and application of same in anti-aging cosmetic

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1839793A (en) * 2006-01-17 2006-10-04 高铎 Beauty and health cosmetics
CN101732201A (en) * 2009-12-31 2010-06-16 玉溪健坤生物药业有限公司 Reduced coenzyme Q10 essence oil and preparation method thereof
CN103202928A (en) * 2012-06-15 2013-07-17 广州环亚化妆品科技有限公司 Traditional Chinese medicine composition with anti-aging function and application of same in anti-aging cosmetic
CN103169637A (en) * 2013-03-13 2013-06-26 广州中涵生物科技有限公司 Cosmetic preparation for repairing aging rough skin and simultaneously repairing large pores

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