CN103734153A - Water-soluble biological insecticide containing active abamectin and preparation method of biological insecticide - Google Patents
Water-soluble biological insecticide containing active abamectin and preparation method of biological insecticide Download PDFInfo
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- CN103734153A CN103734153A CN201410023404.2A CN201410023404A CN103734153A CN 103734153 A CN103734153 A CN 103734153A CN 201410023404 A CN201410023404 A CN 201410023404A CN 103734153 A CN103734153 A CN 103734153A
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- avermectin
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- insecticide
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Abstract
The invention discloses a water-soluble biological insecticide containing active abamectin and a preparation method of the biological insecticide, belongs to the technical field of chemicals for agriculture, relates to an insecticide and solves the problems that a traditional abamectin insecticide is severe in environment pollution and gradually reduced in insecticidal effect. The water-soluble biological insecticide containing active abamectin comprises the following components in percentage by mass: 5-60% of benzalkonium bromide, 0.1-5% of abamectin, 0.5-5% of organic acid, 1-10% of a complexing agent, 0.5-5% of a synergist, 1-10% of alcohol and the balance being water. The water-soluble biological insecticide disclosed by the invention is high in activity, doubled in effect, low in toxic or side effect and convenient in water-soluble application, and can be widely applied to insect killing and suppressing for crops and fish and shrimps in aquaculture.
Description
Technical field
The invention belongs to agricultural and use chemicals technical field, relate to insecticide, be specifically related to a kind of water-soluble biological insecticide containing active Avermectin and preparation method thereof.
Background technology
Existing abamectin insecticide, with the Avermectin of single composition or Avermectin and the compound insecticide of other insecticide compositions mostly, this insecticides has following shortcoming: all adopt benzene class as solvent, it is all the missible oil insecticides of agricultural chemicals type, very large to environmental influence, crop is residual and toxic and side effect is also large, for a long time parasite is easily developed immunity to drugs, and the drug effect of insecticide can weaken gradually.The shortcoming that environmental pollution is large, insecticidal action weakens gradually existing in order to overcome existing abamectin insecticide, is necessary to develop a kind of new insecticide.
Summary of the invention
The present invention is the problem that environmental pollution is large, insecticidal action weakens gradually existing in order to solve existing abamectin insecticide, and a kind of water-soluble biological insecticide containing active Avermectin and preparation method thereof is provided.
The present invention is achieved by the following technical solutions:
Containing a water-soluble biological insecticide for active Avermectin, comprise each component of following mass percent:
Benzalkonium bromide 5～60%
Avermectin 0.1～5%
Organic acid 0.5～5%
Complexing agent 1～10%
Synergist 0.5～5%
Alcohol 1～10%
Surplus is water.
Further, the above-mentioned water-soluble biological insecticide containing active Avermectin, preferably includes each component of following mass percent:
Benzalkonium bromide 20%
Avermectin 0.5%
Organic acid 2%
Complexing agent 5%
Synergist 2%
Alcohol 3%
Water 67.5%.
Described organic acid is neutral organic acid, comprises organic phosphoric acid, glacial acetic acid.
Described complexing agent is DMF or polyethylene glycol.
Described synergist is azone or tween.
The above-mentioned water-soluble biological method for producing insecticide containing active Avermectin, step is:
(1) benzalkonium bromide and organic acid are mixed to rear 8～12 points of kinds that stir under 40 ℃ of conditions of temperature, make acid active body;
(2) Avermectin and complexing agent are mixed to rear stirring 8～12 minutes, make neutral active body;
(3) acid active body, neutral active body, synergist, alcohol, water are mixed, be heated to 50 ℃, stir 50～70 minutes, cooling, discharging gets product.
It is carrier that the present invention selects cation benzalkonium bromide, and benzalkonium bromide has good solubilising and permeability, after Avermectin complexing, generates active Avermectin; But benzalkonium bromide belongs to alkalescence, Avermectin is just stablized at acid condition, thus must first adjust the pH value of benzalkonium bromide, then carry out compoundly with Avermectin, just can generate stable water miscible active Avermectin; Benzalkonium bromide itself is also a kind of bactericide,, clinical application effect is fine, and stability is strong.
By following experimental verification drug effect of the present invention:
One, experiment place: in farmland in romote antiquity, Shanxi, parasite is tested.
Experiment grouping: in 10 experiment groups of field random division, the area of every group is 0.1 mu, and 10 experiment groups are divided into two classes at random, and a class is selected commercially available conventional abamectin insecticide, and a class is selected product of the present invention.
Experimental result: the product of the Avermectin 0.5% of same effective content routine be 1ppm to parasitic desinsection half lethal concentration, and product of the present invention is 0.1-0.2ppm to parasitic desinsection half lethal concentration.
Two, experiment place: by Agricultural University Of Shanxi's Animal Science And Technology, aquaculture base in romote antiquity is tested in Shanxi.
Experiment grouping: 8 culturing pools of random selection in cultivation base, the area of each culturing pool is 0.3 mu, and 8 experiment groups are divided into two classes at random, and a class is selected commercially available conventional abamectin insecticide, and a class is selected product of the present invention.
Experimental result: the product of the Avermectin 0.5% of same effective content routine be 1.1ppm to parasitic desinsection half lethal concentration, and product of the present invention is 0.1-0.2ppm to parasitic desinsection half lethal concentration.
And product of the present invention has good bactericidal action, bacterium and parasite have good preventive and therapeutic action, and conventional Avermectin is very little to bacterial action.
Compared with existing product, Product Activity of the present invention is higher, and effect increases doubly, and toxic and side effect is little, and water-soluble use is more convenient, and can be widely used in crops and aquaculture fish, shrimps desinsection, press down worm.
Embodiment
Embodiment 1
Containing the water-soluble biological insecticide of active Avermectin, each component of preferred following mass percent:
Benzalkonium bromide 20%, Avermectin 0.5%, organic phosphoric acid 2%, DMF complexing agent 5%, azone synergist 2%, alcohol 3%, water 67.5%.
The above-mentioned water-soluble biological method for producing insecticide containing active Avermectin, step is:
(1) benzalkonium bromide and organic phosphoric acid are mixed to the rear 10 points of kinds that stir under 40 ℃ of conditions of temperature, make acid active body;
(2) Avermectin and DMF complexing agent are mixed to rear stirring 10 minutes, make neutral active body;
(3) acid active body, neutral active body, azone synergist, alcohol, water are mixed, be heated to 50 ℃, stir 60 minutes, cooling, discharging gets product.
Embodiment 2
Containing the water-soluble biological insecticide of active Avermectin, each component of preferred following mass percent:
Benzalkonium bromide 5%, Avermectin 2%, glacial acetic acid 0.5%, polyethylene glycol complexing agent 8%, tween synergist 0.5%, alcohol 10%, water 73%.
The above-mentioned water-soluble biological method for producing insecticide containing active Avermectin, step is:
(1) benzalkonium bromide and glacial acetic acid are mixed to the rear 8 points of kinds that stir under 40 ℃ of conditions of temperature, make acid active body;
(2) Avermectin and polyethylene glycol complexing agent are mixed to rear stirring 10 minutes, make neutral active body;
(3) acid active body, neutral active body, tween synergist, alcohol, water are mixed, be heated to 50 ℃, stir 50 minutes, cooling, discharging gets product.
Embodiment 3
Containing the water-soluble biological insecticide of active Avermectin, each component of preferred following mass percent:
Benzalkonium bromide 40%, Avermectin 5%, glacial acetic acid 5%, polyethylene glycol complexing agent 1%, azone synergist 1%, alcohol 7%, water 41%.
The above-mentioned water-soluble biological method for producing insecticide containing active Avermectin, step is:
(1) benzalkonium bromide and glacial acetic acid are mixed to the rear 12 points of kinds that stir under 40 ℃ of conditions of temperature, make acid active body;
(2) Avermectin and polyethylene glycol complexing agent are mixed to rear stirring 8 minutes, make neutral active body;
(3) acid active body, neutral active body, azone synergist, alcohol, water are mixed, be heated to 50 ℃, stir 70 minutes, cooling, discharging gets product.
Embodiment 4
Containing the water-soluble biological insecticide of active Avermectin, each component of preferred following mass percent:
Benzalkonium bromide 60%, Avermectin 0.1%, organic phosphoric acid 1%, polyethylene glycol complexing agent 10%, azone synergist 5%, alcohol 1%, water 22.9%.
The above-mentioned water-soluble biological method for producing insecticide containing active Avermectin, step is:
(1) benzalkonium bromide and organic phosphoric acid are mixed to the rear 8 points of kinds that stir under 40 ℃ of conditions of temperature, make acid active body;
(2) Avermectin and polyethylene glycol complexing agent are mixed to rear stirring 12 minutes, make neutral active body;
(3) acid active body, neutral active body, azone synergist, alcohol, water are mixed, be heated to 50 ℃, stir 60 minutes, cooling, discharging gets product.
Claims (6)
1. containing a water-soluble biological insecticide for active Avermectin, it is characterized in that, comprise each component of following mass percent:
Benzalkonium bromide 5～60%
Avermectin 0.1～5%
Organic acid 0.5～5%
Complexing agent 1～10%
Synergist 0.5～5%
Alcohol 1～10%
Surplus is water.
2. the water-soluble biological insecticide containing active Avermectin according to claim 1, is characterized in that, comprises each component of following mass percent:
Benzalkonium bromide 20%
Avermectin 0.5%
Organic acid 2%
Complexing agent 5%
Synergist 2%
Alcohol 3%
Water 67.5%.
3. the water-soluble biological insecticide containing active Avermectin according to claim 1 and 2, is characterized in that, described organic acid is neutral organic acid, comprises organic phosphoric acid, glacial acetic acid.
4. the water-soluble biological insecticide containing active Avermectin according to claim 1 and 2, is characterized in that, described complexing agent is DMF or polyethylene glycol.
5. the water-soluble biological insecticide containing active Avermectin according to claim 1 and 2, is characterized in that, described synergist is azone or tween.
6. the water-soluble biological method for producing insecticide containing active Avermectin claimed in claim 1, is characterized in that, step is:
(1) benzalkonium bromide and organic acid are mixed to rear 8～12 points of kinds that stir under 40 ℃ of conditions of temperature, make acid active body;
(2) Avermectin and complexing agent are mixed to rear stirring 8～12 minutes, make neutral active body;
(3) acid active body, neutral active body, synergist, alcohol, water are mixed, be heated to 50 ℃, stir 50～70 minutes, cooling, discharging gets product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410023404.2A CN103734153B (en) | 2014-01-20 | 2014-01-20 | A kind of water-soluble biological insecticide containing active Avermectin and preparation method thereof |
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| CN201410023404.2A CN103734153B (en) | 2014-01-20 | 2014-01-20 | A kind of water-soluble biological insecticide containing active Avermectin and preparation method thereof |
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| CN103734153A true CN103734153A (en) | 2014-04-23 |
| CN103734153B CN103734153B (en) | 2016-04-27 |
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| CN201410023404.2A Expired - Fee Related CN103734153B (en) | 2014-01-20 | 2014-01-20 | A kind of water-soluble biological insecticide containing active Avermectin and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107736360A (en) * | 2017-09-30 | 2018-02-27 | 无为县龙口花卉苗木有限公司 | One kind covers shrimp soft-shelled turtle insecticide of breeding fish |
| CN107751196A (en) * | 2017-09-30 | 2018-03-06 | 无为县龙口花卉苗木有限公司 | One kind covers shrimp soft-shelled turtle efficient pesticides of breeding fish |
| CN108042558A (en) * | 2017-12-12 | 2018-05-18 | 长沙拜特生物科技研究所有限公司 | Avermectin preparation used for aquiculture and preparation method thereof |
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| CN1861062A (en) * | 2006-06-14 | 2006-11-15 | 王德昌 | Medicine composition used for fish or other aquatic livings and its prepn. method |
| CN101167479A (en) * | 2007-11-22 | 2008-04-30 | 王德昌 | Insecticidal composition and preparation method thereof |
| CN101589722A (en) * | 2009-06-26 | 2009-12-02 | 南开大学 | Insecticides of a kind of chloride worm benzamide and its production and use |
| WO2010095151A2 (en) * | 2009-02-20 | 2010-08-26 | Deepak Pranjivandas Shah | A novel water dispersible granular composition |
| CN102696674A (en) * | 2012-06-05 | 2012-10-03 | 上海利康消毒高科技有限公司 | Low-concentration hydrogen peroxide disinfectant and preparation method thereof |
| CN103054798A (en) * | 2005-08-31 | 2013-04-24 | 阿布拉科斯生物科学有限公司 | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
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2014
- 2014-01-20 CN CN201410023404.2A patent/CN103734153B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103054798A (en) * | 2005-08-31 | 2013-04-24 | 阿布拉科斯生物科学有限公司 | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
| CN1861062A (en) * | 2006-06-14 | 2006-11-15 | 王德昌 | Medicine composition used for fish or other aquatic livings and its prepn. method |
| CN101167479A (en) * | 2007-11-22 | 2008-04-30 | 王德昌 | Insecticidal composition and preparation method thereof |
| WO2010095151A2 (en) * | 2009-02-20 | 2010-08-26 | Deepak Pranjivandas Shah | A novel water dispersible granular composition |
| CN101589722A (en) * | 2009-06-26 | 2009-12-02 | 南开大学 | Insecticides of a kind of chloride worm benzamide and its production and use |
| CN102696674A (en) * | 2012-06-05 | 2012-10-03 | 上海利康消毒高科技有限公司 | Low-concentration hydrogen peroxide disinfectant and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107736360A (en) * | 2017-09-30 | 2018-02-27 | 无为县龙口花卉苗木有限公司 | One kind covers shrimp soft-shelled turtle insecticide of breeding fish |
| CN107751196A (en) * | 2017-09-30 | 2018-03-06 | 无为县龙口花卉苗木有限公司 | One kind covers shrimp soft-shelled turtle efficient pesticides of breeding fish |
| CN108042558A (en) * | 2017-12-12 | 2018-05-18 | 长沙拜特生物科技研究所有限公司 | Avermectin preparation used for aquiculture and preparation method thereof |
| CN108042558B (en) * | 2017-12-12 | 2020-02-07 | 长沙拜特生物科技研究所有限公司 | Abamectin preparation for aquaculture and preparation method thereof |
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| CN103734153B (en) | 2016-04-27 |
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Effective date of registration: 20181009 Address after: 032100 wangjiabao village, Liu Hulan Town, Wenshui County, Lvliang, Shanxi Patentee after: Shanxi Yi Xintai Biological Technology Co. Ltd. Address before: 032199 Shanxi Yixintai Biotechnology Co., Ltd. of Fenhe Industrial Park, Liu Hulan Town, Wenshui County, Luliang City, Shanxi Province Patentee before: Wang Dechang |
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Granted publication date: 20160427 Termination date: 20190120 |
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