CN103719831A - Method for improving active ingredients of Chinese caterpillar fungus mycelium powder produced by using fermentation method - Google Patents
Method for improving active ingredients of Chinese caterpillar fungus mycelium powder produced by using fermentation method Download PDFInfo
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- CN103719831A CN103719831A CN201310738007.9A CN201310738007A CN103719831A CN 103719831 A CN103719831 A CN 103719831A CN 201310738007 A CN201310738007 A CN 201310738007A CN 103719831 A CN103719831 A CN 103719831A
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- caterpillar fungus
- chinese caterpillar
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
Abstract
The invention relates to a method for improving the active ingredients of Chinese caterpillar fungus mycelium powder produced by using a fermentation method. The method comprises the following steps: (1) concentrating Chinese caterpillar fungus fermentation liquor into liquor with a volume accounting for 30-80% of the volume of the original liquor; (2) carrying out effective emulsifying, dispersing, homogenizing and smashing on the concentrated Chinese caterpillar fungus fermentation liquor by using a colloid mill, so that the particle size of processed Chinese caterpillar fungus mycelium reaches 10-60 micrometers, and the heterogeneity reaches 60-95%; (3) inputting the Chinese caterpillar fungus fermentation liquor subjected to homogenizing and smashing into an ultrahigh pressure cell disruption instrument, wherein the working parameters are as follows: the working pressure is 300-4000 bar, the working temperature is 4-30 DEG C, the number of disruption times is 1-5, and the cell-wall disruption ratio is 70-96%; and (4) after the Chinese caterpillar fungus fermentation liquor subjected to disruption is dried at the temperature of 60-100 DEG C, crushing and sieving the obtained object so as to obtain a Chinese caterpillar fungus mycelium product. According to the invention, artificial Chinese caterpillar fungus mycelium powder is subjected to cell-wall disruption by using an ultrahigh pressure cell disruption method, so that the bacterial cell-wall disruption ratio of the obtained Chinese caterpillar fungus mycelium product reaches over 95%, the adenosine content of the product is increased by more than 10% on the basis of the original content, and the beneficial ingredients in the product can be absorbed by the human body better.
Description
Technical field
The invention belongs to biofermentation and extractive technique field, particularly a kind of method that improves fermentation method production mycelium powder of sinensis active ingredient.
Background technology
Cordyceps sinensis (Cordyceps sinensis) (hereinafter to be referred as Chinese caterpillar fungus), is a kind of traditional Chinese medicine material, is listed as 3 large tonics with ginseng, pilose antler.Its nature and flavor are sweet, flat, return lung, kidney channel, have secret lean gas, nourishing the lung and the kidney, hemostasis and phlegm, adjusting immunity, antiallergy, the anti-ageing effect of waiting for a long time.Because wild resource is very limited, be difficult to meet demand both domestic and external, cause Cordyceps sinensis to become genuine rare medicinal herbs, therefore, both at home and abroad the research of the artificial culture technique of Chinese caterpillar fungus hypha and its medical value is especially paid close attention to.Since the fifties in last century, the states such as the U.S., Japan, Italy successively successfully utilize artificial technology to turn out Chinese caterpillar fungus hypha, and China started the research through more than ten years from 1972, also suitability for industrialized production is successfully developed and dropped into this technology.And through repeatedly to the chemical composition of artificial fermentation's mycelium powder of sinensis and natural cordyceps, comparative study proves with pharmacology: the two main chemical is similar with basic pharmacological action, even artifical fermentation cordyceps hypha powder is stronger than natural cs effect, and side effect still less.Clinical testing confirmation, it is to hyperlipemia, and the illnesss such as sexual disorder, chronic bronchitis all have good curative effect.Through experimental analysis, the bioactivator that the multivitamin containing highly active nucleosides material, 19 seed amino acids, Cordyceps sinensis polysaccharide, high-load in mycelium powder of sinensis, trace element and other are of value to human body is produced in fermentation.Above-mentioned nutriment is mostly product in somatic cells, and how making it better be released and being absorbed by the body is the hot issue that class mycelium powder of sinensis researcher pays close attention to of fermenting at present.And method of cell disruption is whether proper, also directly have influence on Yield and quality and the cost of extracted product.
Cytoclastic method can be divided into Mechanical Method and on-mechanical method, and Mechanical Method comprises pearl mill method, high-pressure homogenization method, ultrasonic, Bo Fa and microwave method etc.; On-mechanical method comprises the methods such as lyase method, acid heat method and autolysis method, the method of using at present exists that breaking-wall cell is incomplete, technology maturity not, technical limitation and produce the problems such as pollution, select a kind of effective release of the intracellular bioactive ingredients of Chinese caterpillar fungus hypha and active ingredient that can make fermenting and producing to be more conducive to absorption of human body, be suitable for again the low cost of suitability for industrialized production, the method that requires such as fast and safely, be the crucial difficult problem that the current artificial aweto scientific research personnel of manufacturing enterprise will solve simultaneously.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of method that improves fermentation method production mycelium powder of sinensis active ingredient is provided, it can make the intracellular bioactive ingredients of Chinese caterpillar fungus hypha of fermenting and producing effectively discharge and active ingredient is more conducive to absorption of human body, low cost, fast and safely.
The present invention solves its technical problem and is achieved through the following technical solutions:
Improve fermentation method and produce a method for mycelium powder of sinensis active ingredient, the steps include:
Improve fermentation method and produce a method for mycelium powder of sinensis active ingredient, the steps include:
(1). cordyceps sinensis fermentation liquor is concentrated into the 30-80% of primary liquid volume;
(2). utilize colloid mill that the cordyceps sinensis fermentation liquor after concentrated is carried out to emulsification effectively, dispersion, homogeneous and pulverizing, make Chinese caterpillar fungus hypha granularity after treatment reach 10-60 micron, homogeneity reaches 60-95%;
(3). the Cordyceps Militaris liquid of pulverizing after homogeneous is inputed to super-pressure cell crushing instrument, and running parameter is: operating pressure 300-4000bar; Operating temperature: 4-30 ℃, broken number of times 1-5 time; Breaking-wall cell rate 70-96%;
(4). the Cordyceps Militaris liquid after fragmentation, after 60-100 ℃ is dried, is pulverized, and sieves, and obtains Chinese caterpillar fungus hypha product.
Advantage of the present invention and beneficial effect are:
The present invention utilizes super-pressure disrupt red cell to artificial cordyceps mycelia's powder cell wall breaking, the somatic cells sporoderm-broken rate of its Chinese caterpillar fungus hypha product reaches more than 95%, in product, adenosine content can improve and be greater than 10% on the original basis, and the beneficiating ingredient in product can be absorbed by the body better, promote the biological health effect of this product, and solved the problem of current industrial fermentation production Chinese caterpillar fungus hypha powder cell wall breaking difficulty.
The specific embodiment
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Improve fermentation method and produce a method for mycelium powder of sinensis active ingredient, the steps include:
(1). cordyceps sinensis fermentation liquor is concentrated into 65% of primary liquid volume;
(2). utilize colloid mill that the cordyceps sinensis fermentation liquor after concentrated is carried out to emulsification effectively, dispersion, homogeneous and pulverizing, make Chinese caterpillar fungus hypha granularity after treatment reach 50 microns, homogeneity reaches 80%;
(3). the Cordyceps Militaris liquid of pulverizing after homogeneous is inputed to super-pressure cell crushing instrument, and running parameter is: operating pressure 1400bar; Operating temperature: 10 ℃, broken number of times 2 times circulates; Final detection draws: fermented cordyceps hypha breaking-wall cell rate 80%;
(4). the Cordyceps Militaris liquid after fragmentation, after 80 ℃ are dried, is pulverized, and sieves, and obtains Chinese caterpillar fungus hypha product.
(5). the mycelium powder of sinensis drawing after cordyceps sinensis fermentation liquor being processed through above-mentioned steps, through adenosine, detect, its adenosine content has and is increased to 0.21% by original 0.2%, and increase rate is 10%, the also corresponding raising of benefit materials content such as other amino acidses, polysaccharide in Chinese caterpillar fungus.
(6). the mycelium powder of sinensis after this technical finesse, the content in the more common hypha powder of bioactive substance content is all significantly improved, and is more of value to absorption of human body, promotes the biological health effect of this product.
Embodiment 2
Improve fermentation method and produce a method for mycelium powder of sinensis active ingredient, the steps include:
(1). cordyceps sinensis fermentation liquor is concentrated into 70% of primary liquid volume;
(2). utilize colloid mill that the cordyceps sinensis fermentation liquor after concentrated is carried out to emulsification effectively, dispersion, homogeneous and pulverizing, make Chinese caterpillar fungus hypha granularity after treatment reach 40 microns, homogeneity reaches 85%;
(3). the Cordyceps Militaris liquid of pulverizing after homogeneous is inputed to super-pressure cell crushing instrument, and running parameter is: operating pressure 1800bar; Operating temperature: 10 ℃, broken number of times 3 times circulates; Final detection draws: fermented cordyceps hypha breaking-wall cell rate 90%;
(4). the Cordyceps Militaris liquid after fragmentation, after 80 ℃ are dried, is pulverized, and sieves, and obtains Chinese caterpillar fungus hypha product.
(5). the mycelium powder of sinensis drawing after cordyceps sinensis fermentation liquor being processed through above-mentioned steps, through adenosine, detect, its adenosine content has and is increased to 0.23% by original 0.2%, and increase rate is 15%, the also corresponding raising of benefit materials content such as other amino acidses, polysaccharide in Chinese caterpillar fungus.
(6). the mycelium powder of sinensis after this technical finesse, the content in the more common hypha powder of bioactive substance content is all significantly improved, and is more of value to absorption of human body, promotes the biological health effect of this product.
Embodiment 3
Improve fermentation method and produce a method for mycelium powder of sinensis active ingredient, the steps include:
(1). cordyceps sinensis fermentation liquor is concentrated into 72% of primary liquid volume;
(2). utilize colloid mill that the cordyceps sinensis fermentation liquor after concentrated is carried out to emulsification effectively, dispersion, homogeneous and pulverizing, make Chinese caterpillar fungus hypha granularity after treatment reach 35 microns, homogeneity reaches 92%;
(3). the Cordyceps Militaris liquid of pulverizing after homogeneous is inputed to super-pressure cell crushing instrument, and running parameter is: operating pressure 2000bar; Operating temperature: 10 ℃, broken number of times 3 times circulates; Final detection draws: fermented cordyceps hypha breaking-wall cell rate 96%;
(4). the Cordyceps Militaris liquid after fragmentation, after 80 ℃ are dried, is pulverized, and sieves, and obtains Chinese caterpillar fungus hypha product.
(5). the mycelium powder of sinensis drawing after cordyceps sinensis fermentation liquor being processed through above-mentioned steps, through adenosine, detect, its adenosine has and is increased to 0.25% by original 0.2% containing two, and increase rate is 25%, the also corresponding raising of benefit materials content such as other amino acidses, polysaccharide in Chinese caterpillar fungus.
(6). the mycelium powder of sinensis after this technical finesse, the content in the more common hypha powder of bioactive substance content is all significantly improved, and is more of value to absorption of human body, promotes the biological health effect of this product.
Although disclose for the purpose of illustration embodiments of the invention, but it will be appreciated by those skilled in the art that: not departing from the spirit and scope of the present invention and claims, various replacements, variation and modification are all possible, therefore, scope of the present invention is not limited to the disclosed content of embodiment.
Claims (1)
1. improve fermentation method and produce a method for mycelium powder of sinensis active ingredient, the steps include:
(1). cordyceps sinensis fermentation liquor is concentrated into the 30-80% of primary liquid volume;
(2). utilize colloid mill that the cordyceps sinensis fermentation liquor after concentrated is carried out to emulsification effectively, dispersion, homogeneous and pulverizing, make Chinese caterpillar fungus hypha granularity after treatment reach 10-60 micron, homogeneity reaches 60-95%;
(3). the Cordyceps Militaris liquid of pulverizing after homogeneous is inputed to super-pressure cell crushing instrument, and running parameter is: operating pressure 300-4000bar; Operating temperature: 4-30 ℃, broken number of times 1-5 time; Breaking-wall cell rate 70-96%;
(4). the Cordyceps Militaris liquid after fragmentation, after 60-100 ℃ is dried, is pulverized, and sieves, and obtains Chinese caterpillar fungus hypha product.
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| CN201310738007.9A CN103719831A (en) | 2013-12-26 | 2013-12-26 | Method for improving active ingredients of Chinese caterpillar fungus mycelium powder produced by using fermentation method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104905262A (en) * | 2015-05-29 | 2015-09-16 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing cordyceps sinensis and lucid ganoderma compound preparation |
| CN116440726A (en) * | 2022-06-16 | 2023-07-18 | 华大工程生物学长荡湖研究所 | Homogenizing circulation control method and feed liquid treatment method |
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| CN1520878A (en) * | 2003-02-13 | 2004-08-18 | 萍 陈 | Preparing process for nutrition and health oral liquid |
| CN1689452A (en) * | 2004-04-28 | 2005-11-02 | 中国食品发酵工业研究院 | Tonify soup of aweto and its production method |
| CN103169126A (en) * | 2013-03-12 | 2013-06-26 | 太原市素有苦荞食品有限公司 | Lucid ganoderma, worm grass and red jujube slurry |
| CN103271951A (en) * | 2013-05-23 | 2013-09-04 | 台建祥 | Method for preparing cordyceps preparations with high adenosine contents |
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- 2013-12-26 CN CN201310738007.9A patent/CN103719831A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1520878A (en) * | 2003-02-13 | 2004-08-18 | 萍 陈 | Preparing process for nutrition and health oral liquid |
| CN1689452A (en) * | 2004-04-28 | 2005-11-02 | 中国食品发酵工业研究院 | Tonify soup of aweto and its production method |
| CN103169126A (en) * | 2013-03-12 | 2013-06-26 | 太原市素有苦荞食品有限公司 | Lucid ganoderma, worm grass and red jujube slurry |
| CN103271951A (en) * | 2013-05-23 | 2013-09-04 | 台建祥 | Method for preparing cordyceps preparations with high adenosine contents |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104905262A (en) * | 2015-05-29 | 2015-09-16 | 湖北省农业科学院农产品加工与核农技术研究所 | Method for preparing cordyceps sinensis and lucid ganoderma compound preparation |
| CN116440726A (en) * | 2022-06-16 | 2023-07-18 | 华大工程生物学长荡湖研究所 | Homogenizing circulation control method and feed liquid treatment method |
| CN116440726B (en) * | 2022-06-16 | 2024-01-19 | 华大工程生物学长荡湖研究所 | Homogenizing circulation control method and feed liquid treatment method |
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Application publication date: 20140416 |