CN103638098A - Tibetan medicinal composition for treating respiratory tract disease as well as preparation and use methods thereof - Google Patents
Tibetan medicinal composition for treating respiratory tract disease as well as preparation and use methods thereof Download PDFInfo
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Abstract
The invention discloses a Tibetan medicinal composition for treating respiratory tract disease as well as preparation and use methods thereof. Active ingredients of the Tibetan medicinal composition for treating respiratory tract disease are prepared from the following raw materials in parts by weight: 4-7 parts of purple bergenia herb, 1-3 parts of younghusband jerusalemsage root, 1-3 parts of artemisia scoparia and 1-3 parts of liquoric root. The Tibetan medicinal composition for treating respiratory tract disease can regulate lung qi, balance rise and fall and treat and prevent at the same time, can be prepared into an oral liquid preparation or a solid preparation, can be used for treating upper respiratory inflammation and symptoms such as nonproductive dry cough or cough with yellow phlegm, fever and dryness of mouth and nose due to lung dryness and lung heat, can clear lung-heat, moisten dryness, eliminate phlegm and stop cough, is stable in curative effect, is small in side effects, is convenient to take for a long time, has the characteristics of safety, high efficiency and treatment of qi and blood, is high in practicability, and is high in popularization and application values.
Description
Technical field
The invention belongs to medical preparing technical field, relate in particular to a kind of Tibetan medicinal composition and preparation using method thereof for the treatment of respiratory tract.
Background technology
Modern society's operating pressure is large, and rhythm of life is fast, causes the patient of upper respiratory tract infection more and more, because wind heat wind is violated lung, heat transformed from stagnated cold, or the reason such as wind-dryness impairing the lung, body body fluid is burnt, gluing of phlegm and heat, impairment of dispersing and descending function of the lung, disturbance of lung-QI, causes upper respiratory tract infection.
Existing medicine is all treated respectively upper respiratory tract infection, and treatment cycle is longer, and curative effect is undesirable, and use cost is high.
Summary of the invention
The invention provides a kind of Tibetan medicinal composition and preparation using method thereof for the treatment of respiratory tract, be intended to solve existing medicine and all upper respiratory tract infection treated respectively, treatment cycle is longer, and curative effect is undesirable, the problem that use cost is high.
The object of the present invention is to provide a kind of Tibetan medicinal composition for the treatment of respiratory tract, the effective ingredient of the Tibetan medicinal composition of this treatment respiratory tract is to be made by the raw material of following parts by weight: 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae.
Further, in the Tibetan medicinal composition of this treatment respiratory tract, also comprise adjunct ingredient, adjunct ingredient is to be made by the raw material of following parts by weight: excipient, solvent, disintegrating agent, correctives, antiseptic, coloring agent, in adjunct ingredient, can adopt water as solvent, adopt carboxymethyl starch to receive as disintegrating agent, adopt sucrose, aspartame, all kinds of essence as correctives.
Further, the Tibetan medicinal composition of this treatment respiratory tract can be made into the oral liquid of decoction, syrup, medicated wine and so on.
Further, the Tibetan medicinal composition of this treatment respiratory tract can be made into the oral solid formulation of granule, capsule, tablet, pill and so on.
Another object of the present invention is to provide a kind of preparation method for the treatment of the Tibetan medicinal composition of respiratory tract, the method that the Tibetan medicinal composition of this treatment respiratory tract is prepared into syrup is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of amount 70% ethanol, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters, and reclaims ethanol;
Under 60 ℃ of conditions, being concentrated into relative density is 1.2 to 1.3, adds dense sucrose slurry to make cane sugar content be not less than 45%.
Further, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into syrup is: every day 2 times, sooner or later take.
Further, the Tibetan medicinal composition of this treatment respiratory tract is prepared into the method for granule and is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters;
Under 60 ℃ of conditions, being concentrated into relative density is 1.15 to 1.25, adds the dextrin of extractum weight 1/2, mix homogeneously, and 60 ℃ of drying under reduced pressure, pulverize, and cross 60 mesh sieves, add 2%～5% aspartame, and 80% ethanol is crossed 20 mesh sieves and is granulated, and 60 ℃ are dry, granulate, subpackage.
Further, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into granule is: every day 2 times, take each 1 bag sooner or later.
Further, the Tibetan medicinal composition of this treatment respiratory tract is prepared into the method for capsule and is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters;
Under 60 ℃ of conditions, being concentrated into relative density is 1.15 to 1.25, adds the dextrin of extractum weight 1/2, mix homogeneously, and 60 ℃ of drying under reduced pressure, pulverize, and cross 60 mesh sieves, and 80% ethanol is crossed 20 mesh sieves and is granulated, and 60 ℃ are dry, granulate, fill capsule.
Further, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into capsule is: every day 3 times, each 4.
The Tibetan medicinal composition for the treatment of respiratory tract provided by the invention and preparation using method thereof, the effective ingredient of the Tibetan medicinal composition of this treatment respiratory tract is to be made by the raw material of following parts by weight: 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae, the full side's conditioning of the Tibetan medicinal composition lung qi of this treatment respiratory tract, up and down balance system, control anti-taking into account, can be prepared into various oral liquids or solid preparation, be used for the treatment of upper respiratory tract infection and with the dryness of the lung, dry cough without phlegm due to lung-heat or cough and tell yellow sputum, heating, mouth and nose are dried disease, can clearing away lung-heat and moistening for dryness, preventing phlegm from forming and stopping coughing, stable curative effect, side effect is little, be convenient to clothes of a specified duration, there is safety, efficiently, the double feature of controlling of QI and blood, practical, having stronger propagation and employment is worth.
Accompanying drawing explanation
Fig. 1 is the realization flow figure of preparation method of the Tibetan medicinal composition of the treatment respiratory tract that provides of the embodiment of the present invention.
The specific embodiment
In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the present invention is described in further detail.Should be appreciated that specific embodiment described herein is only in order to explain the present invention, and be not used in restriction invention.
The object of the present invention is to provide a kind of Tibetan medicinal composition for the treatment of respiratory tract, the effective ingredient of the Tibetan medicinal composition of this treatment respiratory tract is to be made by the raw material of following parts by weight: 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae.
In embodiments of the present invention, in the Tibetan medicinal composition of this treatment respiratory tract, also comprise adjunct ingredient, adjunct ingredient is to be made by the raw material of following parts by weight: excipient, solvent, disintegrating agent, correctives, antiseptic, coloring agent, in adjunct ingredient, can adopt water as solvent, adopt carboxymethyl starch to receive as disintegrating agent, adopt sucrose, aspartame, all kinds of essence as correctives.
In embodiments of the present invention, the Tibetan medicinal composition of this treatment respiratory tract can be made into the oral liquid of decoction, syrup, medicated wine and so on.
In embodiments of the present invention, the Tibetan medicinal composition of this treatment respiratory tract can be made into the oral solid formulation of granule, capsule, tablet, pill and so on.
Fig. 1 shows the realization flow of preparation method of the Tibetan medicinal composition of the treatment respiratory tract that the embodiment of the present invention provides.
The method that the Tibetan medicinal composition of this treatment respiratory tract is prepared into syrup is:
Step S101 adds 10 times of amount 70% ethanol in 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, decocts each 2 hours 2 times;
Step S102, filters, extruding medicinal residues, and merging filtrate, standing over night, filters, and reclaims ethanol;
Step S103, under 60 ℃ of conditions, being concentrated into relative density is 1.2 to 1.3, adds dense sucrose slurry to make cane sugar content be not less than 45%.
In embodiments of the present invention, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into syrup is: every day 2 times, sooner or later take.
In embodiments of the present invention, the Tibetan medicinal composition of this treatment respiratory tract is prepared into the method for granule and is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters;
Under 60 ℃ of conditions, being concentrated into relative density is 1.15 to 1.25, adds the dextrin of extractum weight 1/2, mix homogeneously, and 60 ℃ of drying under reduced pressure, pulverize, and cross 60 mesh sieves, add 2%～5% aspartame, and 80% ethanol is crossed 20 mesh sieves and is granulated, and 60 ℃ are dry, granulate, subpackage.
In embodiments of the present invention, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into granule is: every day 2 times, take each 1 bag sooner or later.
In embodiments of the present invention, the Tibetan medicinal composition of this treatment respiratory tract is prepared into the method for capsule and is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters;
Under 60 ℃ of conditions, being concentrated into relative density is 1.15 to 1.25, adds the dextrin of extractum weight 1/2, mix homogeneously, and 60 ℃ of drying under reduced pressure, pulverize, and cross 60 mesh sieves, and 80% ethanol is crossed 20 mesh sieves and is granulated, and 60 ℃ are dry, granulate, fill capsule.
In embodiments of the present invention, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into capsule is: every day 3 times, each 4.
Below in conjunction with drawings and the specific embodiments, application principle of the present invention is further described.
Embodiment mono-: active ingredient compositions: Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia, Radix Glycyrrhizae;
The method of making syrup is: Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia and Radix Glycyrrhizae are added to 10 times of amount 70% ethanol, decoct each 2 hours 2 times, filter extruding medicinal residues, merging filtrate, standing over night, filter, reclaim ethanol, be concentrated into relative density and be 1.2 to 1.3(60 ℃), add dense sucrose slurry appropriate, make cane sugar content be not less than 45%(g/ml), every day 2 times, sooner or later take.
Embodiment bis-: active ingredient compositions: Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia, Radix Glycyrrhizae;
The method of granulation agent is: in Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct 2 times, each 2 hours, filter, extruding medicinal residues, merging filtrate, standing over night, filters, be concentrated into relative density and be 1.15 to 1.25(60 ℃), add the dextrin of extractum weight 1/2, mix homogeneously, 60 ℃ of drying under reduced pressure, pulverize, cross 60 mesh sieves, add 2%～5% aspartame, 80% ethanol is crossed 20 mesh sieves and is granulated, 60 ℃ dry, granulate, subpackage, every day 2 times, take each 1 bag sooner or later.
Embodiment tri-: active ingredient compositions: Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia, Radix Glycyrrhizae;
The method of making capsule is: in Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times, filter extruding medicinal residues, merging filtrate, standing over night, filters, and is concentrated into relative density and is 1.15 to 1.25(60 ℃), the dextrin that adds extractum weight 1/2, mix homogeneously, 60 ℃ of drying under reduced pressure, pulverize, cross 60 mesh sieves, 80% ethanol is crossed 20 mesh sieves and is granulated, 60 ℃ dry, granulate, fill capsule.Every day 3 times, each 4.
Clinical efficacy:
1. clinical basic document: select the course of disease 3～5 years, 237 patients that tcm clinical practice syndrome differential diagnosis is upper respiratory tract infection, male 134 people wherein, during its symptom, cough every day reaches 30～50 times, heating and very asthma etc.Yellow fur, rapid pulse.
2. Therapeutic Method: take the circumstances into consideration to give Tibetan medicinal composition provided by the invention according to weight in patients, age, symptom, each Tibetan medicine is 3～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae by weight, plus-minus, and inform decoction instructions of taking, being every dose boils twice with decocting, collecting decoction, a minute morning and evening takes for twice, or preparation patent medicine usage and dosage.
3. treatment effectiveness evaluation standard
Cure: bring down a fever, without breathing heavily, cough disappears, the transference cures such as poor sleep and yellow fur rapid pulse, and do not recur for 2 weeks;
Significantly effectively: bring down a fever, without breathing heavily, occasionally cough, the transference cures such as poor sleep and yellow fur rapid pulse, but recurrence;
Take a turn for the better effectively: heating, asthma, cough, the symptoms such as transference cure such as poor sleep and yellow fur rapid pulse partly alleviate;
Invalid: heating, asthma, cough, the symptoms such as poor sleep and yellow fur rapid pulse do not alleviate.
4. therapeutic outcome: clinical practice therapeutic outcome is in Table 1.
Table 1 upper respiratory tract infection patient treatment result
Two, model case
1. poplar, man, 69 years old, diagnosis on April 14th, 2010.With gastral cavilty portion pain, have hotness, have a surplus the February of repeatedly showing effect; Tibetan medicine's syndrome differential diagnosis: gastral cavilty portion distending pain, xerostomia hardship, noisy pantothenic acid, urine are not well, red tongue, yellowish fur, slippery and rapid pulse; Gastroscopy result: gastric mucosa congestion, edema, red and white, there is pimple sample protuberance, be umbilical opening sample depression central authorities rotten to the corn; Biopsy result is that atypical hyperplasia changes.Medication: with 12 parts of parts by weight Radix phlomidis younghusbandiis, 10 parts of Artemisia scoparias, 10 parts of Rhizoma Seu Herba Bergeniaes, 10 parts, Radix Glycyrrhizae, decoct decoction.Take 1 dose of pain relieving, preventing or arresting vomiting, take 3 doses of pantothenic acid and disappear, take the bitter disappearance of 5 doses of xerostomias, urine is normal, serve on after first quarter moon, and disease all disappears, recurrence in a year, and gastroscope check mucosal inflammation disappears.
Tight certain, man, 53 years old, diagnosis on April 17th, 2010.Hypochondriac pain bitter taste, touch a tender spot obviously and tenderness, or lead and take on the back of the body, pantothenic acid, anorexia is greasy, time and have a stomachache, the stagnant knot of urine, light red tongue, white and thin fur, stringy and thready pulse; Ultrasound diagnosis: gallbladder wall is crude, thicken; Gastroscopy result: gastric mucosa film congestion and edema, have ulcer surface.Medication: with 12 parts of parts by weight Radix phlomidis younghusbandiis, 10 parts of Artemisia scoparias, 10 parts of Rhizoma Seu Herba Bergeniaes, 12 parts, Radix Glycyrrhizae, decoct decoction.Take 1 dose of pain relieving, pantothenic acid disappears, take 7 doses of diseases and disappear, after take 3 weeks, recurrence in a year, B ultrasonic check gallbladder wall is smooth, gastroscope check stomach lining inflammation disappears.
Three, Experiment of Compatibility
The technology of the present invention method is as follows:
According to Uniform ity Design Method, four minister cough-relieving sides are designed to 8 kinds of formulas, be labeled as respectively N
1, N
2, N
3..., N
8, design table (schedule) 5 row as front in table 2.
Table 2 four design of minister cough-relieving compatibility optimization experiment and results
The method of citric acid soln ultrasonic atomizatio for the present invention, causes cough by Cavia porcellus, and observation Cavia porcellus coughs the time that reaction occurs for the first time, is designated as cough latent period, and records the cough number of times in 5min, the results are shown in Table 2 rear 2 row.The present invention's discovery, the number of times of coughing if take is leading indicator, and the cough suppressing effect of group 3 and group 2 is the most obvious, and Rhizoma Seu Herba Bergeniae 0.3～2.4, Radix phlomidis younghusbandii 0.3～0.6, Artemisia scoparia 0.6～1.2, Radix Glycyrrhizae 0.038～2.4g/kg.If calculate in proportion, Rhizoma Seu Herba Bergeniae: Radix phlomidis younghusbandii: Artemisia scoparia: Radix Glycyrrhizae=(0.72～0.07): (0.09～0.13): (0.18～0.72): (0.11～0.53).
The active ingredient of the Tibetan medicinal composition of this treatment respiratory tract is comprised of Rhizoma Seu Herba Bergeniae, Radix phlomidis younghusbandii, Artemisia scoparia and Radix Glycyrrhizae etc., Rhizoma Seu Herba Bergeniae heat-clearing and toxic substances removing, cough-relieving hemostasis; Radix phlomidis younghusbandii is relieving cough and reducing sputum, clearing away heat and cooling blood; Artemisia scoparia is lung heat clearing, cough-relieving, evacuation of pus; Radix Glycyrrhizae replenishing and restoring lung-QI, nourishing the lung to arrest cough.Entirely can breathe heavily heat symptom-complex shape for upper respiratory tract infection and with disturbance of lung-QI and the expectoration of impairment of dispersing and descending function of the lung type, as diseases such as dry cough without phlegm, heating, asthma, there is the features such as stable curative effect, side effect be little.Scorching the ruling together in full side, up and down balance system, controls anti-taking into account.
The Tibetan medicinal composition for the treatment of respiratory tract provided by the invention is comprised of following medical material formula: 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae
Active ingredient recipe principle of the present invention is: clearing away lung-heat and moistening for dryness, preventing phlegm from forming and stopping coughing.
Rhizoma Seu Herba Bergeniae---sweet in the mouth, puckery, cool in nature, return liver, lung, spleen channel.Heat-clearing and toxic substances removing, cough-relieving hemostasis, regulating menstruation.For pulmonary tuberculosis cough, spitting of blood, spits blood, and epistaxis, has blood in stool, enteritis, dysentery, dysfunctional uterine hemorrhage, leucorrhea, menoxenia; The external chickenpox of harnessing the Yellow River.
Radix phlomidis younghusbandii---sweet in the mouth, flat, relieving cough and reducing sputum, clearing away heat and cooling blood.For cold cough, bronchitis, and control skin ulcer of a specified duration and do not heal.
Artemisia scoparia---bitter in the mouth, pungent, cool in nature.Lung heat clearing, cough-relieving, evacuation of pus.Cure mainly cough due to lung-heat, the syndrome of dyspnea, pulmonary abscess, cold cough, " heat of fighting ", laryngopharynx swelling and pain.
Radix Glycyrrhizae---sweet in the mouth, flat, return spleen, stomach, lung meridian, QI invigorating invigorating middle warmer; Relieving spasm to stop pain; Nourishing the lung to arrest cough; Eliminating fire and detoxication; Coordinating the actions of various ingredients in a prescription.Main asthenia lack of appetite; Leanness yellowish complexion; Shortness of breath and palpitation; Stomachache loose stool; The anxious pain of extremity contraction; Hysteria; Cough and asthma; Laryngopharynx swelling and pain; Carbuncle skin ulcer swells and ache; Infantile carbuncle; And medicine, alimentary toxicosis.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Tibetan medicinal composition for the treatment of respiratory tract provided by the invention also can add excipient, and as water equal solvent, carboxymethyl starch such as receives at the disintegrating agent, the correctivess such as sucrose, aspartame, all kinds of essence, antiseptic, coloring agent.
The Tibetan medicinal composition for the treatment of respiratory tract provided by the invention can comparatively fast be cured upper respiratory tract infection, and determined curative effect is reliable, successful, and total effective rate is 98.59%, cure rate is 87.68%, and does not find untoward reaction phenomenon.
The Tibetan medicinal composition for the treatment of respiratory tract provided by the invention be take natural drug as raw material, is used for the treatment of the pharmaceutical composition of upper respiratory tract infection, has safety, efficient, the double feature of controlling of QI and blood, and by removing heat from the lung and dissipating phlegm, clearing away lung-heat and moistening for dryness reaches therapeutic effect.
The Tibetan medicinal composition of the treatment respiratory tract that the embodiment of the present invention provides and preparation using method thereof, the effective ingredient of the Tibetan medicinal composition of this treatment respiratory tract is to be made by the raw material of following parts by weight: 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae, the full side's conditioning of the Tibetan medicinal composition lung qi of this treatment respiratory tract, up and down balance system, control anti-taking into account, can be prepared into various oral liquids or solid preparation, be used for the treatment of upper respiratory tract infection and with the dryness of the lung, dry cough without phlegm due to lung-heat or cough and tell yellow sputum, heating, mouth and nose are dried disease, can clearing away lung-heat and moistening for dryness, preventing phlegm from forming and stopping coughing, stable curative effect, side effect is little, be convenient to clothes of a specified duration, there is safety, efficiently, the double feature of controlling of QI and blood, practical, having stronger propagation and employment is worth.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any modifications of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. a Tibetan medicinal composition for the treatment of respiratory tract, is characterized in that, the effective ingredient of the Tibetan medicinal composition of this treatment respiratory tract is to be made by the raw material of following parts by weight: 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia, 1～3 part, Radix Glycyrrhizae.
2. the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 1, it is characterized in that, in the Tibetan medicinal composition of this treatment respiratory tract, also comprise adjunct ingredient, adjunct ingredient is to be made by the raw material of following parts by weight: excipient, solvent, disintegrating agent, correctives, antiseptic, coloring agent, in adjunct ingredient, can adopt water as solvent, adopt carboxymethyl starch to receive as disintegrating agent, adopt sucrose, aspartame, all kinds of essence as correctives.
3. the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 1, is characterized in that, the Tibetan medicinal composition of this treatment respiratory tract can be made into the oral liquid of decoction, syrup, medicated wine and so on.
4. the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 1, is characterized in that, the Tibetan medicinal composition of this treatment respiratory tract can be made into the oral solid formulation of granule, capsule, tablet, pill and so on.
5. a preparation method for the treatment of the Tibetan medicinal composition of respiratory tract, is characterized in that, the method that the Tibetan medicinal composition of this treatment respiratory tract is prepared into syrup is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of amount 70% ethanol, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters, and reclaims ethanol;
Under 60 ℃ of conditions, being concentrated into relative density is 1.2 to 1.3, adds dense sucrose slurry to make cane sugar content be not less than 45%.
6. the preparation method of the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 5, is characterized in that, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into syrup is: every day 2 times, sooner or later take.
7. the preparation method of the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 5, is characterized in that, the method that the Tibetan medicinal composition of this treatment respiratory tract is prepared into granule is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters;
Under 60 ℃ of conditions, being concentrated into relative density is 1.15 to 1.25, adds the dextrin of extractum weight 1/2, mix homogeneously, and 60 ℃ of drying under reduced pressure, pulverize, and cross 60 mesh sieves, add 2%～5% aspartame, and 80% ethanol is crossed 20 mesh sieves and is granulated, and 60 ℃ are dry, granulate, subpackage.
8. the preparation method of the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 7, is characterized in that, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into granule is: every day 2 times, take each 1 bag sooner or later.
9. the preparation method of the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 5, is characterized in that, the method that the Tibetan medicinal composition of this treatment respiratory tract is prepared into capsule is:
In 1～3 part, 4～7 parts of Rhizoma Seu Herba Bergeniaes, 1～3 part of Radix phlomidis younghusbandii, 1～3 part of Artemisia scoparia and Radix Glycyrrhizae, add 10 times of water gagings, decoct each 2 hours 2 times;
Filter, extruding medicinal residues, merging filtrate, standing over night, filters;
Under 60 ℃ of conditions, being concentrated into relative density is 1.15 to 1.25, adds the dextrin of extractum weight 1/2, mix homogeneously, and 60 ℃ of drying under reduced pressure, pulverize, and cross 60 mesh sieves, and 80% ethanol is crossed 20 mesh sieves and is granulated, and 60 ℃ are dry, granulate, fill capsule.
10. the preparation method of the Tibetan medicinal composition for the treatment of respiratory tract as claimed in claim 9, is characterized in that, the instructions of taking that the Tibetan medicinal composition of this treatment respiratory tract is prepared into capsule is: every day 3 times, each 4.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113640440A (en) * | 2021-08-24 | 2021-11-12 | 西藏藏医药大学 | Method for identifying effective ingredients in four-minister cough-relieving granules |
| CN113671091A (en) * | 2021-08-24 | 2021-11-19 | 西藏藏医药大学 | Method for detecting blood-entering chemical components of four-minister cough-relieving granules |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113640440A (en) * | 2021-08-24 | 2021-11-12 | 西藏藏医药大学 | Method for identifying effective ingredients in four-minister cough-relieving granules |
| CN113671091A (en) * | 2021-08-24 | 2021-11-19 | 西藏藏医药大学 | Method for detecting blood-entering chemical components of four-minister cough-relieving granules |
| CN113640440B (en) * | 2021-08-24 | 2023-10-27 | 西藏藏医药大学 | Method for identifying effective components in Sichen cough relieving granules |
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Application publication date: 20140319 |