CN103623384B - 一种治疗寒湿证型妊娠水肿病的中药 - Google Patents
一种治疗寒湿证型妊娠水肿病的中药 Download PDFInfo
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Abstract
一种治疗寒湿证型妊娠水肿病的中药，其特征是由下列重量配比的原料制成的：茯苓15份、干姜6份、白术20份、甘草10份、当归10份、白芍10份、防已12份。本发明采用合适的中药及其配比，各药物之间相互配合，协同作用，所制成的中药具有散寒去湿，利湿消肿，通阳利水的功效，五年来通过对66名患者的使用表明，有效率达94%。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗寒湿证型妊娠水肿病的中药。
背景技术
妊娠后，肢体面目等部位发生浮肿，称“妊娠水肿”，亦称“妊娠肿胀”。有的孕妇在妊娠3～4个月后出现妊娠水肿，表现为面目肿胀渐及下肢，甚至遍及全身，从中医的角度来看，妊娠水肿主要有肾阳虚证型、寒湿证型、气滞湿阻证型、脾阳虚证型妊娠水肿病等。寒湿证型妊娠水肿病是妊娠水肿的一种，目前治疗妊娠水肿病主要是采用中药治疗，但目前还没有一种专用于治疗寒湿证型妊娠水肿病的中药。
发明内容
本发明的目的旨在提供一种治疗寒湿证型妊娠水肿病的中药，通过选择合适的药材及其配比，达到安全有效治愈寒湿证型妊娠水肿病的目的。
为达到上述目的，本发明采用以下技术方案：
一种治疗寒湿证型妊娠水肿病的中药，其特征是由下列重量配比的原料制成的：
茯苓15份、干姜6份、白术20份、甘草10份、当归10份、白芍10份、防已12份。
本发明配方所采用的各种药材的功能主治如下：
茯苓【来源】 本品为多孔菌科真菌茯苓 Poria cocos （Schw.） Wolf 的干燥菌核。【性味】 甘、淡，平。【归经】 归心、肺、脾、肾经。
【功能主治】 利水渗湿，健脾宁心。用于水肿尿少，痰饮眩悸，脾虚食少，便溏泄泻，心神不安，惊悸失眠。
干姜【来源】 本品为姜科植物姜Zingiber officinale Rosc.的干燥根茎。【性味】 辛、热。【归经】 归脾、胃、肾、心、肺经。【功能主治】 干姜温中散寒，回阳通脉，燥湿消痰。用于脘腹冷痛，呕吐泄泻，肢冷脉微，痰饮喘咳。
白术【来源】 本品为菊科植物白术Atractylodes macrocephala Koidz.的干燥根茎。【性味】 苦、甘，温。【归经】 归脾、胃经。
【功能主治】 健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。土白术健脾，和胃，安胎。用于脾虚食少，泄泻便溏，胎动不安。
甘草【来源】 本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【性味】 甘，平。【归经】 归心、肺、脾、胃经 。【功能主治】 补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
当归【来源】 本品为伞形科植物当归Angelica sinensis （Oliv.） Diels 的干燥根。【性味】 甘、辛，温。【归经】 归肝、心、脾经。
【功能主治】 补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。酒当归活血通经。用于经闭痛经，风湿痹痛，跌扑损伤。
白芍【来源】 本品为毛茛科植物芍药Paeonia lactiflora Pall. 的干燥根。【性味】 苦、酸，微寒。【归经】 归肝、脾经。【功能主治】 平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，月经不调，自汗，盗汗。
防己【来源】为防已科植物粉防已睥块根。【性味】味苦，辛，性寒。【归经】膀胱，肺，脾经。【功能主治】利水消肿，祛风止痛。主治水肿，小便不利，风湿痹痛，脚气肿痛，疥癣疮肿，高血压病。
寒湿证型妊娠水肿，临床表现为妊娠数月，面目四肢浮肿或遍及全身，食欲不振、大便溏薄，舌质胖嫩，苔薄白或腻、边有齿痕，脉缓滑无力。本发明采用合适的中药及其配比，各药物之间相互配合，协同作用，所制成的中药具有散寒去湿，利湿消肿，通阳利水的功效，五年来通过对66名患者的使用表明，有效率达94%。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2007年6月-2013年5月间共收集了102例寒湿证型妊娠水肿病门诊患者，年龄28-36岁，病情3-16天。随机分为：治疗组66例，对照组36例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1对照组口服五皮饮，按照说明书服用。疗程15天。
2.2治疗组口服本发明按照具体实施例1制得的胶囊，早、中、晚各一次。疗程15天。
3、疗效标准及治疗结果
3.1疗效标准：
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率（%） |
| 治疗组 | 66 | 38 | 24 | 4 | 94% |
| 对照组 | 36 | 7 | 19 | 10 | 72% |
由此可见，本发明制得的药物能够安全有效治疗寒湿证型妊娠水肿病。
具体实施方式
为了更好地理解与实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取茯苓15克、干姜6克、白术20克、甘草10克、当归10克、白芍10克、防已12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗寒湿证型妊娠水肿病。口服，每日分早、中、晚三次服用。
具体实施例2
称取茯苓15克、干姜6克、白术20克、甘草10克、当归10克、白芍10克、防已12克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人1天用量的散剂。
用于治疗寒湿证型妊娠水肿病。口服，每日分早、中、晚三次服用。
具体实施例3
称取茯苓15克、干姜6克、白术20克、甘草10克、当归10克、白芍10克、防已12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即得符合正常成人1天用量的颗粒剂。
用于治疗寒湿证型妊娠水肿病。口服，每日分早、中、晚三次服用。
Claims (1)
1.一种治疗寒湿证型妊娠水肿病的中药，其特征是由下列重量配比的原料制成的：茯苓15份、干姜6份、白术20份、甘草10份、当归10份、白芍10份、防已12份。
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