CN103572507A - Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane - Google Patents

Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane Download PDF

Info

Publication number
CN103572507A
CN103572507A CN201210258495.9A CN201210258495A CN103572507A CN 103572507 A CN103572507 A CN 103572507A CN 201210258495 A CN201210258495 A CN 201210258495A CN 103572507 A CN103572507 A CN 103572507A
Authority
CN
China
Prior art keywords
nano
silk fibroin
solution
fibroin
electrostatic spinning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201210258495.9A
Other languages
Chinese (zh)
Inventor
周涓
朱君
施丽君
钟建
闫志强
魏岱旭
何丹农
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai National Engineering Research Center for Nanotechnology Co Ltd
Original Assignee
Shanghai National Engineering Research Center for Nanotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai National Engineering Research Center for Nanotechnology Co Ltd filed Critical Shanghai National Engineering Research Center for Nanotechnology Co Ltd
Priority to CN201210258495.9A priority Critical patent/CN103572507A/en
Publication of CN103572507A publication Critical patent/CN103572507A/en
Pending legal-status Critical Current

Links

Abstract

The invention relates to a preparation method for a nanofiber membrane which mixed nano materials which have an antibiosis ultraviolet prevention property and silk fibroin. The preparation method for the antibiosis ultraviolet prevention silk fibroin nanofiber membrane comprises performing surface modification on the nano materials which have the antibiosis ultraviolet prevention performance, adding into a prepared silk fibroin solution and mixing and forming into a spinning solution and obtaining the antibiosis ultraviolet prevention silk fibroin nanofiber membrane through the electrostatic spinning technique. The preparation method for the antibiosis ultraviolet prevention silk fibroin nanofiber membrane has the advantages of enabling nanoscale composite fibers obtained through the electrostatic spinning technique to have good biocompatibility as the silk fibroin, meanwhile to have the antibiosis ultraviolet prevention performance as photocatalysis type nano-antibacterial materials, to be applicable to biomedicine field and particularly to be capable of serving as cover materials for killing bacteria and treating infected wound surface and being simple in preparation technology, low in production cost and capable of satisfying production and application requirements.

Description

The preparation method of antibiotic anti-ultraviolet silk fibroin nano-fiber film
Technical field
The present invention relates to a kind of nanofiber and preparation method thereof, be specifically related to a kind of have antibiotic, uv resistance can nano material and the nano fibrous membrane of fibroin albumen blend and preparation method thereof.This method belongs to the technology of preparing of fiber, and prepared material can be widely used in the fields such as biological medicine.
Background technology
Fibroin albumen is a kind of protein extracting from silk, there is good biocompatibility, the material that can prepare the variforms such as film forming, gel, powder, physicochemical property due to its uniqueness, fibroin material is studied widely in field of biomedical materials at present, as immobilised enzymes material, cell culture substrate, medicinal slow release agent, artificial organs etc.In order to improve the performance of fibroin albumen, make it be applied to better technical field of biological material, in recent years, Chinese scholars has been carried out chemical modification by distinct methods to fibroin albumen, has obtained some new achievements in research.For example, the modification by fibroin albumen improves the physicochemical properties such as mechanical property, heat endurance of fibroin material; Change the rate of release of fibroin material to medicine; Give fibroin material blood-clot resistance, antibiotic property etc.Wherein, preparation antibiotic property fibroin protein film has become one of focus of research, and it is expected to become a kind of energy kill bacteria, the cladding material for the treatment of infective wound surface.
Antibiotic property fibroin protein film mainly comprises load antibiotic property medicine and loads nano anti-biotic material.Antibiotic property drug main will refer to antibiotic medicine, still, due to a large amount of uses of antibiotic medicine, makes pathogenic microorganism for hiding medicine, and in constantly variation, antibody-resistant bacterium also produces thereupon, has even occurred " superbacteria ".Its result causes antibiotic medicine result for the treatment of variation, even invalid.Nano anti-biotic material is the new material that a class possesses bacteriostasis property.Due to the high-specific surface area of antiseptic in material and the special effects of high reaction activity, greatly improved whole antibacterial effect, can make microorganism comprise that the Growth and reproduction of bacterium, fungi, saccharomycete, algae and virus etc. keeps lower level.Nano anti-biotic material can be divided into 3 classes again by Antibacterial Mechanism: the 1st class is the metal mold nano antibacterial agents such as silver (Ag); The 2nd class is quaternary ammonium salt or quaternary alkylphosphonium salt modification inorganic nanoparticles; The 3rd class is nano zine oxide (ZnO), nano titanium oxide (TiO 2) etc. photocatalyst-type nano anti-biotic material.Wherein, the 1st, 2 class anti-biotic materials all have report, and as existing antibacterial action, and the application of the photocatalyst-type nano anti-biotic material that has again an anti-ultraviolet effect in fibroin protein film has not yet to see report.
Electrostatic spinning technique is one and prepares the simple and effective technology of nanometer stage material.Polymer melt or solution, under high-pressure electrostatic effect, utilize electric field force to overcome polymer solution surface tension and form one charged injection stream, and solvent evaporates is solidified afterwards, and nano-scale fiber is arranged on collecting board disorderly, forms similar non-woven fabrics fiber film.Electrostatic spinning technique has been advantageously applied to prepares silk fibroin nano-fiber film, and prepared tunica fibrosa has the Morphological Features that fibre number is thin, surface area is large, porosity is high and can be used as the porous support of Growth of Cells, promotes migration and the propagation of cell; Also can be used as artificial graft's blood vessel, surface of a wound cladding material and pharmaceutical carrier, be widely used as organizational project and bio-medical engineering material.
Summary of the invention
The object of the invention is for the deficiencies in the prior art, provide a kind of have antibiotic, uv resistance can the preparation method-be Surface Modification of Nanosized Materials antibiotic by having, uv resistance energy of nano material and the nano fibrous membrane of fibroin albumen blend, join again in the silk fibroin protein solution of preparation, be mixed to form spinning solution, then by electrostatic spinning technique, prepare antibiotic, anti-ultraviolet silk fibroin nano-fiber film.
The preparation method who the invention provides a kind of antibiotic anti-ultraviolet silk fibroin nano-fiber film, is characterized in that, comprises the steps:
1) surface modification of nano material: by nano material, be dissolved in the aqueous solution that contains surfactant, making its mol ratio is 1:0.5～1:10, under ultrasound condition, reacts 4 hours; After reaction, solution, through centrifugal, washing, obtains the nano material of surface modification after being dried;
2) preparation of fibroin albumen: it is to stir in 0.5% sodium carbonate liquor that silk cocoon is put into mass percent concentration, boil the silk gum of removing silk cocoon surface for 60 minutes, after washing with water, at 60 ℃, be dried and prepare fibroin fiber, the calcium chloride that is 1:8:2 by dry fibroin fiber and mol ratio: water: the mixed solution of ethanol, at 75 ℃, be dissolved into silk fibroin protein solution, through dialysis, remove ethanol and the calcium chloride in solution, filtration makes silk fibroin protein solution, then obtained by freeze drying fibroin albumen;
3) preparation of electrostatic spinning raw material solution: according to weight ratio 1:0.05～0.3:0.005～0.05, the nano material of solvent, fibroin albumen and surface modification is mixed, ultrasonic dispersion 0.5 hour, stirs 4 hours, forms the electrostatic spinning raw material solution of homogeneous;
4) electrostatic spinning: the electrostatic spinning raw material solution of preparation is injected to electrostatic spinning apparatus, prepare antibiotic, anti-ultraviolet silk fibroin nano-fiber film.
Described nano material is photocatalyst-type nano anti-biotic material, is specially nano titanium oxide (TiO 2), nano zine oxide (ZnO), nano-stannic oxide (SnO 2), nano tungsten trioxide (WO 3), nanometer vanadium trioxide (V 2o 3), silver ion doped nano titanium dioxide (Ag-TiO 2), copper ion doped nano titanium oxide (Cu-TiO 2), a kind of in silver ion nanometer doped zinc oxide (Ag-ZnO), copper ion doped nano zine oxide (Cu-ZnO).
Described surfactant is softex kw (CTAB), lauryl sodium sulfate (SDS), neopelex (SDBS), sodium hexadecyl sulfate, sodium stearyl sulfate, potassium stearate, potassium oleate, potassium laurate, odium stearate, enuatrol, sodium laurate, polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), Tween-80 (Tu-80), ethoxylated dodecyl alcohol (Brij-35), Triton X-100 (Triton X-100), Pluronic F127 (Pluronic F127), a kind of in Pluronic P123 (Pluronic P123).
Described solvent is a kind of in water, formic acid, hexafluoroisopropanol, Hexafluoro acetone, trifluoroethanol.
Described electrostatic spinning process is 8～30 kilovolts of voltages, 0.1～2 ml/hour of liquid inventory, and receiving range is 10～20 centimetres.
The invention has the advantages that: pass through electrostatic spinning technique, prepare nano level composite fibre, make this fiber both there is the biocompatibility that fibroin albumen is good, the characteristic that simultaneously has both again antibiotic, the anti-ultraviolet of photocatalyst-type nano anti-biotic material, be more suitable for biomedical sector, can can eliminate bacterium as a kind of especially, the cladding material for the treatment of infective wound surface.Preparation technology of the present invention is simple, and production cost is low, can further meet the demand of producing and applying.
Accompanying drawing explanation
Fig. 1 is the stereoscan photograph of the prepared nano fibrous membrane of embodiment 1.
The specific embodiment
By specific embodiment, technical scheme of the present invention is further described below.Following embodiment further illustrates of the present invention, and does not limit the scope of the invention.
Embodiment 1:
1) by a certain amount of nano-ZnO, be dissolved in 20 milliliters of aqueous solution that contain PVP, making its mol ratio is 1:1, under ultrasound condition, reacts 4 hours.After reaction, solution, through centrifugal, washing, obtains the nano-ZnO of surface modification after being dried.
2) silk cocoon being put into mass percent concentration is to stir in 0.5% sodium carbonate liquor, boil the silk gum of removing silk cocoon surface for 60 minutes, after washing with water, under 60 ° of C, be dried and prepare fibroin fiber, the mixed solution of calcium chloride, water and the ethanol that is 1:8:2 by dry fibroin fiber and mol ratio, under 75 ° of C, be dissolved into silk fibroin protein solution, through dialysis, remove ethanol and the calcium chloride in solution, filter and make silk fibroin protein solution, then obtained by freeze drying fibroin albumen.
3) according to weight ratio 1:0.1:0.01, the nano-ZnO of water, fibroin albumen and PVP surface modification is mixed, ultrasonic dispersion 0.5 hour, stirs 4 hours, forms the electrostatic spinning raw material solution of homogeneous.
4) electrostatic spinning raw material solution of preparation is injected to electrostatic spinning apparatus, prepare nano fibrous membrane.Electrostatic spinning process is: 10 kilovolts of voltages, and 0.1 ml/hour of liquid inventory, receiving range is 10 centimetres.
Fig. 1 is the stereoscan photograph of prepared nano fibrous membrane.As seen from the figure, the diameter of nanofiber is 200 nanometers.5 minutes is 98.7% to colibacillary bacteriostasis rate.
Embodiment 2:
1) by a certain amount of nano-TiO 2, be dissolved in 20 milliliters of aqueous solution that contain Triton X-100, making its mol ratio is 1:5, under ultrasound condition, reacts 4 hours.After reaction, solution, through centrifugal, washing, obtains the nano-TiO of surface modification after being dried 2.
2) silk cocoon being put into mass percent concentration is to stir in 0.5% sodium carbonate liquor, boil the silk gum of removing silk cocoon surface for 60 minutes, after washing with water, under 60 ° of C, be dried and prepare fibroin fiber, the mixed solution of calcium chloride, water and the ethanol that is 1:8:2 by dry fibroin fiber and mol ratio, under 75 ° of C, be dissolved into silk fibroin protein solution, through dialysis, remove ethanol and the calcium chloride in solution, filter and make silk fibroin protein solution, then obtained by freeze drying fibroin albumen.
3) according to weight ratio 1:0.3:0.05 by the nano-TiO of water, fibroin albumen and Triton X-100 surface modification 2mix, ultrasonic dispersion 0.5 hour, stirs 4 hours, forms the electrostatic spinning raw material solution of homogeneous.
4) electrostatic spinning raw material solution of preparation is injected to electrostatic spinning apparatus, prepare nano fibrous membrane.Electrostatic spinning process is: 15 kilovolts of voltages, and 0.1 ml/hour of liquid inventory, receiving range is 10 centimetres.5 minutes is 95.8% to colibacillary bacteriostasis rate.
Embodiment 3:
1) by a certain amount of nano-ZnO, be dissolved in 20 milliliters of aqueous solution that contain PVA, making its mol ratio is 1:0.5, under ultrasound condition, reacts 4 hours.After reaction, solution, through centrifugal, washing, obtains the nano-ZnO of surface modification after being dried.
2) silk cocoon being put into mass percent concentration is to stir in 0.5% sodium carbonate liquor, boil the silk gum of removing silk cocoon surface for 60 minutes, after washing with water, under 60 ° of C, be dried and prepare fibroin fiber, the mixed solution of calcium chloride, water and the ethanol that is 1:8:2 by dry fibroin fiber and mol ratio, under 75 ° of C, be dissolved into silk fibroin protein solution, through dialysis, remove ethanol and the calcium chloride in solution, filter and make silk fibroin protein solution, then obtained by freeze drying fibroin albumen.
3) according to weight ratio 1:0.2:0.01, the nano-ZnO of hexafluoroisopropanol, fibroin albumen and PVA surface modification is mixed, ultrasonic dispersion 0.5 hour, stirs 4 hours, forms the electrostatic spinning raw material solution of homogeneous.
4) electrostatic spinning raw material solution of preparation is injected to electrostatic spinning apparatus, prepare nano fibrous membrane.Electrostatic spinning process is: 20 kilovolts of voltages, and 0.2 ml/hour of liquid inventory, receiving range is 15 centimetres.5 minutes is 97.1% to colibacillary bacteriostasis rate.
Embodiment 4:
1) by a certain amount of nanometer Ag-TiO 2, be dissolved in 20 milliliters of aqueous solution that contain potassium oleate, making its mol ratio is 1:8, under ultrasound condition, reacts 4 hours.After reaction, solution, through centrifugal, washing, obtains the nanometer Ag-TiO of surface modification after being dried 2.
2) silk cocoon being put into mass percent concentration is to stir in 0.5% sodium carbonate liquor, boil and within 60 minutes, go out the silk gum on silk cocoon surface, extract, after washing with water, under 60 ° of C, be dried and prepare fibroin fiber, the calcium chloride that is 1:8:2 by dry fibroin fiber and mol ratio, the mixed solution of second alcohol and water are dissolved into silk fibroin protein solution under 75 ° of C, through dialysis, remove ethanol and the calcium chloride in solution, filtration makes silk fibroin protein solution, then obtained by freeze drying fibroin albumen.
3) according to weight ratio 1:0.1:0.005 by the nanometer Ag-TiO of trifluoroethanol, fibroin albumen and potassium oleate surface modification 2mix, ultrasonic dispersion 0.5 hour, stirs 4 hours, forms the electrostatic spinning raw material solution of homogeneous.
4) electrostatic spinning raw material solution of preparation is injected to electrostatic spinning apparatus, prepare nano fibrous membrane.Electrostatic spinning process is: 15 kilovolts of voltages, and 0.2 ml/hour of liquid inventory, receiving range is 10 centimetres.5 minutes is 99.2% to colibacillary bacteriostasis rate.

Claims (5)

1. a preparation method for antibiotic anti-ultraviolet silk fibroin nano-fiber film, is characterized in that, comprises the steps:
1) surface modification of nano material: by nano material, be dissolved in the aqueous solution that contains surfactant, making its mol ratio is 1:0.5～1:10, under ultrasound condition, reacts 4 hours; After reaction, solution, through centrifugal, washing, obtains the nano material of surface modification after being dried;
2) preparation of fibroin albumen: it is to stir in 0.5% sodium carbonate liquor that silk cocoon is put into mass percent concentration, boil the silk gum of removing silk cocoon surface for 60 minutes, after washing with water, at 60 ℃, be dried and prepare fibroin fiber, the calcium chloride that is 1:8:2 by dry fibroin fiber and mol ratio: water: the mixed solution of ethanol, at 75 ℃, be dissolved into silk fibroin protein solution, through dialysis, remove ethanol and the calcium chloride in solution, filtration makes silk fibroin protein solution, then obtained by freeze drying fibroin albumen;
3) preparation of electrostatic spinning raw material solution: according to weight ratio 1:0.05～0.3:0.005～0.05, the nano material of solvent, fibroin albumen and surface modification is mixed, ultrasonic dispersion 0.5 hour, stirs 4 hours, forms the electrostatic spinning raw material solution of homogeneous;
4) electrostatic spinning: the electrostatic spinning raw material solution of preparation is injected to electrostatic spinning apparatus, prepare antibiotic, anti-ultraviolet silk fibroin nano-fiber film.
2. the preparation method of antibiotic anti-ultraviolet silk fibroin nano-fiber film according to claim 1, is characterized in that, described nano material is photocatalyst-type nano anti-biotic material, is specially nano titanium oxide (TiO 2), nano zine oxide (ZnO), nano-stannic oxide (SnO 2), nano tungsten trioxide (WO 3), nanometer vanadium trioxide (V 2o 3), silver ion doped nano titanium dioxide (Ag-TiO 2), copper ion doped nano titanium oxide (Cu-TiO 2), a kind of in silver ion nanometer doped zinc oxide (Ag-ZnO), copper ion doped nano zine oxide (Cu-ZnO).
3. the preparation method of antibiotic anti-ultraviolet silk fibroin nano-fiber film according to claim 1, it is characterized in that, described surfactant is softex kw (CTAB), lauryl sodium sulfate (SDS), neopelex (SDBS), sodium hexadecyl sulfate, sodium stearyl sulfate, potassium stearate, potassium oleate, potassium laurate, odium stearate, enuatrol, sodium laurate, polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), Tween-80 (Tu-80), ethoxylated dodecyl alcohol (Brij-35), Triton X-100 (Triton X-100), Pluronic F127 (Pluronic F127), a kind of in Pluronic P123 (Pluronic P123).
4. the preparation method of antibiotic anti-ultraviolet silk fibroin nano-fiber film according to claim 1, is characterized in that, described solvent is a kind of in water, formic acid, hexafluoroisopropanol, Hexafluoro acetone, trifluoroethanol.
5. the preparation method of antibiotic anti-ultraviolet silk fibroin nano-fiber film according to claim 1, is characterized in that, described electrostatic spinning process is 8～30 kilovolts of voltages, 0.1～2 ml/hour of liquid inventory, and receiving range is 10～20 centimetres.
CN201210258495.9A 2012-07-24 2012-07-24 Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane Pending CN103572507A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210258495.9A CN103572507A (en) 2012-07-24 2012-07-24 Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210258495.9A CN103572507A (en) 2012-07-24 2012-07-24 Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane

Publications (1)

Publication Number Publication Date
CN103572507A true CN103572507A (en) 2014-02-12

Family

ID=50045178

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201210258495.9A Pending CN103572507A (en) 2012-07-24 2012-07-24 Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane

Country Status (1)

Country Link
CN (1) CN103572507A (en)

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104451933A (en) * 2014-12-09 2015-03-25 张丽明 Method for preparing nano-fiber material containing sericin/nano carbon
CN105839294A (en) * 2016-05-23 2016-08-10 浙江理工大学 Method for preparing nanocrystalline cellulose-fibroin film by electrostatic spinning method
CN106192062A (en) * 2016-09-23 2016-12-07 安徽丰磊制冷工程有限公司 A kind of high performance Static Spinning/electret composite fibre filtering material and preparation method thereof
CN106436316A (en) * 2016-09-23 2017-02-22 安徽丰磊制冷工程有限公司 High abrasion resistance electrostatic spinning/electret composite cellulosic film filter material and preparing method thereof
CN106435829A (en) * 2016-11-14 2017-02-22 安徽名杰净化科技有限公司 Vinyl polysiloxane-containing electrostatic spinning and electret composite fiber filter material and preparation method thereof
CN106512556A (en) * 2016-11-14 2017-03-22 安徽名杰净化科技有限公司 Dendritic electrostatic spinning/electret composite nanofiber membrane filter material and preparation method thereof
CN106512553A (en) * 2016-11-14 2017-03-22 安徽名杰净化科技有限公司 Electrostatic spun/electret composite fiber filter material comprising sodium tartrate intercalated hydrotalcite and preparation method of filter material
CN106621563A (en) * 2016-11-14 2017-05-10 安徽名杰净化科技有限公司 Gelatin/polyetherimide compound electret fiber filtration material prepared through electrostatic spinning and preparation method thereof
CN106676753A (en) * 2016-12-28 2017-05-17 嘉兴学院 Antibacterial nano fiber and preparation method thereof
CN107254742A (en) * 2017-07-03 2017-10-17 河南工程学院 The composite fiber web of polyvinyl alcohol/sericin containing Nano Silver for medical dressing
CN107552095A (en) * 2017-09-17 2018-01-09 钱景 The silk three-dimensional porous material and preparation method of carried titanium dioxide Nano Silver
CN108299832A (en) * 2018-03-06 2018-07-20 苏州先蚕丝绸有限公司 A kind of preparation method of fibroin aquagel membrane
CN108714237A (en) * 2018-06-01 2018-10-30 苏州先蚕丝绸有限公司 A kind of natural silk adhesive bandage
CN108744995A (en) * 2018-06-06 2018-11-06 广州康盛生物科技有限公司 A kind of antibacterial composite hollow fiber membrane and preparation method thereof
CN109097851A (en) * 2018-06-27 2018-12-28 苏州市贝克生物科技有限公司 Fibroin material and preparation method thereof
CN109244316A (en) * 2018-08-30 2019-01-18 浙江理工大学 A kind of preparation method of the fibroin base nano carbon fibre film applied to lithium-sulfur cell interlayer
CN109295722A (en) * 2018-09-11 2019-02-01 东华大学 Keratin assists the preparation method of fixed photocatalytic nanometer particle functionalization carpet
CN109853068A (en) * 2019-01-30 2019-06-07 东华大学 A kind of carbon quantum dot/fibroin composite nano fiber and its preparation method and application
CN110158239A (en) * 2018-03-28 2019-08-23 山东佳星环保科技有限公司 A kind of preparation method of antibacterial graphene nano fiber film
CN110465189A (en) * 2019-08-09 2019-11-19 浙江理工大学 A kind of preparation method of fibroin base air filter film
CN111453760A (en) * 2020-04-22 2020-07-28 安徽锦华氧化锌有限公司 Preparation process of nano zinc oxide with antibacterial property
CN112143306A (en) * 2020-09-17 2020-12-29 鹤山市顺鑫实业有限公司 Covering base film and preparation method thereof
CN112169007A (en) * 2020-09-23 2021-01-05 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of antibacterial fiber membrane based on electrostatic spinning
CN112323262A (en) * 2020-09-30 2021-02-05 苏州大学 Electrostatic spinning porous carbon material and preparation method thereof
CN112515976A (en) * 2020-12-11 2021-03-19 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of nano dry facial mask
CN112538181A (en) * 2020-12-07 2021-03-23 武汉大学 Preparation method of zinc oxide nanoparticle-fibroin composite antibacterial film
CN112575448A (en) * 2020-12-11 2021-03-30 浙江理工大学 Preparation method of porous non-woven fabric with antibacterial function

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1408146A1 (en) * 2001-03-14 2004-04-14 Japan as represented by President of Tokyo University of Agriculture and Technology Non-woven fabric comprising ultra-fine fiber of silk fibroin and/or silk-like material, and method for production thereof
CN1837274A (en) * 2005-03-21 2006-09-27 中国科学院化学研究所 Degradable and absorbable polymer nano fibrous membrane materials and preparation process and use thereof
CN101077473A (en) * 2007-06-22 2007-11-28 上海兰度科技有限公司 Novel environmental protection fiber film material and its preparation method
CN101358382A (en) * 2008-08-26 2009-02-04 东华大学 Antibacterial nano fiber material and preparation method thereof
JP2010150712A (en) * 2008-12-25 2010-07-08 Shinshu Univ Silk protein nano-fiber, method for producing the same, silk protein composite nano-fiber, and method for producing the same
CN101856510A (en) * 2010-05-14 2010-10-13 浙江理工大学 Preparation method of composite nano-fiber support material of silk fibroin and calcium silicate
CN102140760A (en) * 2011-04-07 2011-08-03 上海交通大学 Method for preparing fibroin modified nano zinc oxide biocompatible material
CN102418263A (en) * 2010-05-26 2012-04-18 新加坡国立大学 Nano material modified or functionalized silk protein-based material and preparation method thereof
CN102513044A (en) * 2011-12-16 2012-06-27 黑龙江省科学院高技术研究院 Surface modification method of nanometer aluminum oxide

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1408146A1 (en) * 2001-03-14 2004-04-14 Japan as represented by President of Tokyo University of Agriculture and Technology Non-woven fabric comprising ultra-fine fiber of silk fibroin and/or silk-like material, and method for production thereof
CN1837274A (en) * 2005-03-21 2006-09-27 中国科学院化学研究所 Degradable and absorbable polymer nano fibrous membrane materials and preparation process and use thereof
CN101077473A (en) * 2007-06-22 2007-11-28 上海兰度科技有限公司 Novel environmental protection fiber film material and its preparation method
CN101358382A (en) * 2008-08-26 2009-02-04 东华大学 Antibacterial nano fiber material and preparation method thereof
JP2010150712A (en) * 2008-12-25 2010-07-08 Shinshu Univ Silk protein nano-fiber, method for producing the same, silk protein composite nano-fiber, and method for producing the same
CN101856510A (en) * 2010-05-14 2010-10-13 浙江理工大学 Preparation method of composite nano-fiber support material of silk fibroin and calcium silicate
CN102418263A (en) * 2010-05-26 2012-04-18 新加坡国立大学 Nano material modified or functionalized silk protein-based material and preparation method thereof
CN102140760A (en) * 2011-04-07 2011-08-03 上海交通大学 Method for preparing fibroin modified nano zinc oxide biocompatible material
CN102513044A (en) * 2011-12-16 2012-06-27 黑龙江省科学院高技术研究院 Surface modification method of nanometer aluminum oxide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
汪怀远: "《化工新材料概论》", 31 January 2012, article "《化工新材料概论》", pages: 189-190 *

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104451933B (en) * 2014-12-09 2016-04-13 浙江天濮环保科技有限公司 The method of the nano-fiber material of preparation containing sericin/nano-sized carbon
CN104451933A (en) * 2014-12-09 2015-03-25 张丽明 Method for preparing nano-fiber material containing sericin/nano carbon
CN105839294A (en) * 2016-05-23 2016-08-10 浙江理工大学 Method for preparing nanocrystalline cellulose-fibroin film by electrostatic spinning method
CN106192062A (en) * 2016-09-23 2016-12-07 安徽丰磊制冷工程有限公司 A kind of high performance Static Spinning/electret composite fibre filtering material and preparation method thereof
CN106436316A (en) * 2016-09-23 2017-02-22 安徽丰磊制冷工程有限公司 High abrasion resistance electrostatic spinning/electret composite cellulosic film filter material and preparing method thereof
CN106621563A (en) * 2016-11-14 2017-05-10 安徽名杰净化科技有限公司 Gelatin/polyetherimide compound electret fiber filtration material prepared through electrostatic spinning and preparation method thereof
CN106435829A (en) * 2016-11-14 2017-02-22 安徽名杰净化科技有限公司 Vinyl polysiloxane-containing electrostatic spinning and electret composite fiber filter material and preparation method thereof
CN106512556A (en) * 2016-11-14 2017-03-22 安徽名杰净化科技有限公司 Dendritic electrostatic spinning/electret composite nanofiber membrane filter material and preparation method thereof
CN106512553A (en) * 2016-11-14 2017-03-22 安徽名杰净化科技有限公司 Electrostatic spun/electret composite fiber filter material comprising sodium tartrate intercalated hydrotalcite and preparation method of filter material
CN106676753A (en) * 2016-12-28 2017-05-17 嘉兴学院 Antibacterial nano fiber and preparation method thereof
CN107254742A (en) * 2017-07-03 2017-10-17 河南工程学院 The composite fiber web of polyvinyl alcohol/sericin containing Nano Silver for medical dressing
CN107254742B (en) * 2017-07-03 2019-04-05 河南工程学院 The composite fiber web of polyvinyl alcohol/sericin containing nano silver for medical dressing
CN107552095A (en) * 2017-09-17 2018-01-09 钱景 The silk three-dimensional porous material and preparation method of carried titanium dioxide Nano Silver
CN108299832A (en) * 2018-03-06 2018-07-20 苏州先蚕丝绸有限公司 A kind of preparation method of fibroin aquagel membrane
CN110158239A (en) * 2018-03-28 2019-08-23 山东佳星环保科技有限公司 A kind of preparation method of antibacterial graphene nano fiber film
CN108714237A (en) * 2018-06-01 2018-10-30 苏州先蚕丝绸有限公司 A kind of natural silk adhesive bandage
CN108744995A (en) * 2018-06-06 2018-11-06 广州康盛生物科技有限公司 A kind of antibacterial composite hollow fiber membrane and preparation method thereof
CN108744995B (en) * 2018-06-06 2019-04-23 广州康盛生物科技有限公司 A kind of antibacterial composite hollow fiber membrane and preparation method thereof
CN109097851A (en) * 2018-06-27 2018-12-28 苏州市贝克生物科技有限公司 Fibroin material and preparation method thereof
CN109244316A (en) * 2018-08-30 2019-01-18 浙江理工大学 A kind of preparation method of the fibroin base nano carbon fibre film applied to lithium-sulfur cell interlayer
CN109244316B (en) * 2018-08-30 2021-08-20 浙江理工大学 Preparation method of fibroin-based carbon nanofiber membrane applied to lithium-sulfur battery interlayer
CN109295722B (en) * 2018-09-11 2021-12-10 东华大学 Preparation method of keratin-assisted fixation photocatalytic nanoparticle functionalized carpet
CN109295722A (en) * 2018-09-11 2019-02-01 东华大学 Keratin assists the preparation method of fixed photocatalytic nanometer particle functionalization carpet
CN109853068B (en) * 2019-01-30 2021-08-10 东华大学 Carbon quantum dot/fibroin composite nanofiber and preparation method and application thereof
CN109853068A (en) * 2019-01-30 2019-06-07 东华大学 A kind of carbon quantum dot/fibroin composite nano fiber and its preparation method and application
CN110465189A (en) * 2019-08-09 2019-11-19 浙江理工大学 A kind of preparation method of fibroin base air filter film
CN111453760A (en) * 2020-04-22 2020-07-28 安徽锦华氧化锌有限公司 Preparation process of nano zinc oxide with antibacterial property
CN112143306A (en) * 2020-09-17 2020-12-29 鹤山市顺鑫实业有限公司 Covering base film and preparation method thereof
CN112169007A (en) * 2020-09-23 2021-01-05 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of antibacterial fiber membrane based on electrostatic spinning
CN112323262A (en) * 2020-09-30 2021-02-05 苏州大学 Electrostatic spinning porous carbon material and preparation method thereof
CN112538181A (en) * 2020-12-07 2021-03-23 武汉大学 Preparation method of zinc oxide nanoparticle-fibroin composite antibacterial film
CN112515976A (en) * 2020-12-11 2021-03-19 上海纳米技术及应用国家工程研究中心有限公司 Preparation method of nano dry facial mask
CN112575448A (en) * 2020-12-11 2021-03-30 浙江理工大学 Preparation method of porous non-woven fabric with antibacterial function
CN112575448B (en) * 2020-12-11 2022-04-15 浙江理工大学 Preparation method of porous non-woven fabric with antibacterial function

Similar Documents

Publication Publication Date Title
CN103572507A (en) Preparation method for antibiosis ultraviolet prevention silk fibroin nanofiber membrane
Qasim et al. Electrospinning of chitosan-based solutions for tissue engineering and regenerative medicine
Shabafrooz et al. Electrospun nanofibers: from filtration membranes to highly specialized tissue engineering scaffolds
Rezaei et al. Application of cellulosic nanofibers in food science using electrospinning and its potential risk
Garg et al. Biomaterials-based nanofiber scaffold: targeted and controlled carrier for cell and drug delivery
Naseri et al. Electrospun chitosan-based nanocomposite mats reinforced with chitin nanocrystals for wound dressing
Nezarati et al. Effects of humidity and solution viscosity on electrospun fiber morphology
Konwarh et al. Electrospun cellulose acetate nanofibers: the present status and gamut of biotechnological applications
Rodríguez-Tobías et al. Novel antibacterial electrospun mats based on poly (d, l-lactide) nanofibers and zinc oxide nanoparticles
Ma et al. Electrospun sodium alginate/poly (ethylene oxide) core–shell nanofibers scaffolds potential for tissue engineering applications
Chen et al. Electrically-responsive core-shell hybrid microfibers for controlled drug release and cell culture
Mokhena et al. Electrospun alginate nanofibers toward various applications: A review
CN106048892A (en) Preparation method of GO/SA/PVA composite nanofiber membrane carrying nano silver particles
Wang et al. Advances in electrospinning of natural biomaterials for wound dressing
Jao et al. Fabrication and characterization of electrospun silk fibroin/TiO2 nanofibrous mats for wound dressings
CN102493126A (en) Composite fiber material containing nanosilver and preparation method thereof
CN103361885A (en) Preparation method of antibacterial silk fibroin fibrous membrane
CN101187089A (en) Silk fibroin and polyvinyl alcohol blending antibacterial nanometer fiber and its preparation method
Talwar et al. Associative polymer facilitated electrospinning of nanofibers
CN107469127A (en) The preparation method of natural polysaccharide derivative/natural polymer composite fibre medical wound dressing
CN104153120A (en) Antibacterial medical dressing film carrying nano-silver and cellulose nanocrystalline hybrid materials and preparation method thereof
Yadav et al. Electrospinning: an efficient biopolymer-based micro-and nanofibers fabrication technique
El Fawal Polymer nanofibers electrospinning: A review
Kchaou et al. Electrospun nanofibrous scaffolds: Review of current progress in the properties and manufacturing process, and possible applications for COVID-19
KR101033278B1 (en) Improved preparation method of PVA nanofiber membrane using electrospinning

Legal Events

Date Code Title Description
PB01 Publication
C06 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20140212

C12 Rejection of a patent application after its publication