CN103520698B - A kind of medicine for the treatment of dysmenorrhea - Google Patents
A kind of medicine for the treatment of dysmenorrhea Download PDFInfo
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Abstract
The invention discloses a kind of medicine for the treatment of dysmenorrhea, belong to the field of Chinese medicines.This medicine is made by the raw material of Chinese medicine of following weight: river Radix Aconiti Lateralis Preparata 5 ~ 15 parts, Hirudo 1 ~ 10 part, Radix Bupleuri 1 ~ 10 part, Rhizoma Zingiberis 1 ~ 10 part, Cortex Cinnamomi 1 ~ 10 part, Fructus Foeniculi 5 ~ 15 parts, Herba Asari 1 ~ 5 part, Ramulus Cinnamomi 1 ~ 5 part, Fructus Evodiae 1 ~ 5 part, Folium Artemisiae Argyi 1 ~ 10 part, Oletum Trogopterori 1 ~ 10 part, Rhizoma Corydalis 1 ~ 10 part, Radix Angelicae Sinensis 5 ~ 15 parts, Rhizoma Chuanxiong 1 ~ 10 part, Pollen Typhae 1 ~ 10 part, Radix Notoginseng 1 ~ 10 part, Herba Leonuri 5 ~ 15 parts, 1 ~ 10 part, Semen Persicae, 1 ~ 10 part, Flos Carthami, the Radix Paeoniae Alba 1 ~ 10 part, Rhizoma Cyperi 1 ~ 10 part, the Radix Linderae 1 ~ 10 part, Rhizoma Curcumae 1 ~ 10 part, Semen Vaccariae 1 ~ 10 part, 1 ~ 10 part, Radix Glycyrrhizae.We's warming the interior cold expelling, promoting of the circulation of QI and removing the obstruction in the collaterals, blood circulation promoting and blood stasis dispelling are ruled together, and help the Radix Paeoniae Alba with yin fluid astringing simultaneously, and the Pollen Typhae of promoting blood circulation and hemostasis, Radix Notoginseng are dispeled cold and not impairment of YIN, blood circulation promoting and blood stasis dispelling and unlikely metrorrhagia, evident in efficacy to QI stagnated by cold blood stasis type dysmenorrhea.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of medicine for the treatment of dysmenorrhea.
Background technology
Dysmenorrhea is one of common gynecological disease, can be divided into primary dysmenorrhea and secondary dysmenorrhea, refers to that women is on the occasion of menstrual period or front and back of passing through, occur periodically lower abdomen pain, or pain draws waist sacrum, with Nausea and vomiting, cold extremities time serious, very then severe pain is fainted, also known as " abdominal pain during menstruation ".
Dysmenorrhea can be divided into primary dysmenorrhea and secondary dysmenorrhea, primary dysmenorrhea is cyclic menses phase pain but does not have organic disease, and secondary dysmenorrhea is common in gynecopathy, muscular tumor, inflammatory pelvic disease, adenomyosis, endometrial polyp and menstruation outflow obstruction.Therefore, secondary dysmenorrhea often with other gynecological's symptoms, as dysuria, abnormal bleeding, hysteromyoma or infertile.The medicine for the treatment of dysmenorrhea in prior art is a lot, but therapeutic effect is significant few.
Summary of the invention
The present invention proposes a kind of medicine for the treatment of dysmenorrhea, this medicine instant effect, can eliminate fast, relieving dysmenorrhea symptom, treatment cycle be short, evident in efficacy, and raw material is easy to get.
Technical solution of the present invention comprises:
A kind of medicine for the treatment of dysmenorrhea, it is made by the raw material of Chinese medicine of following weight: river Radix Aconiti Lateralis Preparata 5 ~ 15 parts, Hirudo 1 ~ 10 part, Radix Bupleuri 1 ~ 10 part, Rhizoma Zingiberis 1 ~ 10 part, Cortex Cinnamomi 1 ~ 10 part, Fructus Foeniculi 5 ~ 15 parts, Herba Asari 1 ~ 5 part, Ramulus Cinnamomi 1 ~ 5 part, Fructus Evodiae 1 ~ 5 part, Folium Artemisiae Argyi 1 ~ 10 part, Oletum Trogopterori 1 ~ 10 part, Rhizoma Corydalis 1 ~ 10 part, Radix Angelicae Sinensis 5 ~ 15 parts, Rhizoma Chuanxiong 1 ~ 10 part, Pollen Typhae 1 ~ 10 part, Radix Notoginseng 1 ~ 10 part, Herba Leonuri 5 ~ 15 parts, 1 ~ 10 part, Semen Persicae, 1 ~ 10 part, Flos Carthami, the Radix Paeoniae Alba 1 ~ 10 part, Rhizoma Cyperi 1 ~ 10 part, the Radix Linderae 1 ~ 10 part, Rhizoma Curcumae 1 ~ 10 part, Semen Vaccariae 1 ~ 10 part, 1 ~ 10 part, Radix Glycyrrhizae.
As a preferred version of the present invention, the weight of above-mentioned each raw material of Chinese medicine is: river Radix Aconiti Lateralis Preparata 10 parts, Hirudo 5 parts, Radix Bupleuri 5 parts, Rhizoma Zingiberis 5 parts, Cortex Cinnamomi 5 parts, Fructus Foeniculi 10 parts, Herba Asari 2.5 parts, Ramulus Cinnamomi 2.5 parts, Fructus Evodiae 2.5 parts, Folium Artemisiae Argyi 5 parts, Oletum Trogopterori 5 parts, Rhizoma Corydalis 5 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Chuanxiong 5 parts, Pollen Typhae 5 parts, Radix Notoginseng 5 parts, Herba Leonuri 10 parts, 5 parts, Semen Persicae, 5 parts, Flos Carthami, the Radix Paeoniae Alba 5 parts, Rhizoma Cyperi 5 parts, the Radix Linderae 5 parts, Rhizoma Curcumae 5 parts, Semen Vaccariae 5 parts, 5 parts, Radix Glycyrrhizae.
Said medicine specifically adopts following step to make:
A takes raw material respectively according to above-mentioned weight proportion, soaks 1 hour after merging, and the addition of described water is 6 ~ 8 times of raw material gross weight, then decocts 1 hour, filters, obtains filtrate one and medicinal residues;
Gained medicinal residues in step a are decocted with water 1 hour by b again, filter, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three;
Described filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20 by c, dries, pulverizes, make pill, obtain medicine.
Pharmacology of the present invention and beneficial effect:
Dysmenorrhea is common clinical, and traditional Chinese medical herbal treatment is widely used and with the obvious advantage.What dysmenorrhea was mainly blamed appoints in liver,spleen,kidney and punching, and " Jing Yue's complete work married woman rule " are to the cause of disease of dysmenorrhea and discuss comparatively detailed: " abdominal pain during menstruation, card has deficiency and excess.Reality person, or because of cold stagnant, or because of stasis, or because of the stagnation of QI, or because of heat stagnation; Void person, has because of blood deficiency, has because of the deficiency of vital energy." main pathogenesis of dysmenorrhea is cold coagulation, the stagnation of QI, blood stasis, deficiency of qi and blood, deficiency of the liver and kindey, heat in blood etc., cause hematogenous blockage, stagnation of QI and blood may bring about pain, cause dysmenorrhea.Clinical middle discovery, present dysmenorrhea patient, how due to generally unhygienic diet, throw off restraint that food is cold and cool, daily life clothing accidentally, the feelings will reason such as not relax causes cold coagulation, the stagnation of QI, blood stasis, therefore in the majority with excess syndrome.
In the present invention, river Radix Aconiti Lateralis Preparata warming YANG, Radix Bupleuri circulation of qi promoting, Hirudo are invigorated blood circulation, three medicines are monarch, Cortex Cinnamomi, Fructus Foeniculi, Herba Asari, Ramulus Cinnamomi, Fructus Evodiae warming YANG and promoting blood circulation, Rhizoma Chuanxiong, Rhizoma Cyperi, the Radix Linderae, Rhizoma Curcumae, the pain relieving of Semen Vaccariae depressed liver-energy dispersing and QI regulating, Oletum Trogopterori, Rhizoma Corydalis, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami promoting blood circulation, removing blood stasis and relieving pain, below be ministerial drug altogether, assistant restrains anti-catharsis too impairment of YIN with the Radix Paeoniae Alba, Pollen Typhae, pseudo-ginseng blood-circulation-invigovating are stopped blooding anti-Massive Bleeding and arrive or collapse or leak, Radix Glycyrrhizae relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, with Radix Paeoniae Alba sour and sweet drugs can transforme into YIN and for making medicine.Make a general survey of full side, warming the interior cold expelling, promoting of the circulation of QI and removing the obstruction in the collaterals, blood circulation promoting and blood stasis dispelling are ruled together, and help the Radix Paeoniae Alba with yin fluid astringing simultaneously, and the Pollen Typhae of promoting blood circulation and hemostasis, Radix Notoginseng are dispeled cold and not impairment of YIN, blood circulation promoting and blood stasis dispelling and unlikely metrorrhagia, therefore evident in efficacy to QI stagnated by cold blood stasis type dysmenorrhea.
Clinical data:
1, case selection: select out-patient 120 example according to " obstetrics and gynecology ", " Gynecology of Chinese Medicine ", " new Chinese medicine guideline of clinical investigations ", divide into groups according to table of random number, be divided into treatment group and each 60 examples of matched group, all patient's courses of disease are all between half a year to 10 year, age, two groups of patients did not have significant difference in age, the course of disease, the state of an illness etc. between 15 years old to 33 years old;
1.1 case inclusion criterias
(1) age 15-33 year, outpatient service and meet the patient of observation in hospital;
(2) according to the QI stagnated by cold blood stasis type dysmenorrhea patient that " obstetrics and gynecology ", " Gynecology of Chinese Medicine ", " new Chinese medicine guideline of clinical investigations " are diagnosed;
(3) clinical manifestation has periodically inferior belly gas pain, very then tenderness, or cold type of pain, obtains warm then light; Menstruation is purple dark, has clot, or mammary swelling, or feelings will is not relaxed, or aversion to cold and cold limbs etc., light red tongue or purple dark, have ecchymosis, stringy pulse is tight or heavy.
1.2 case exclusion standards
(1) secondary dysmenorrhea patient;
(2) Chinese medical discrimination does not belong to the patient of QI stagnated by cold syndrome of blood stasis and has metrorrhagia patient;
(3) severe primary disease and the psychotics such as the heart, brain, kidney and hemopoietic system is merged;
(4) allergic constitution patient.
1.3 cases come off
(1) do not take medicine by regulation, initiatively exit experimenter;
(2) irritated to trial drug or occur other untoward reaction persons, but should charge in untoward reaction and evaluate.
2, Therapeutic Method
(1) treatment group: oral, each 6 grams, every day 2 times, premenstrual 5 days of the moon started to take, not drug withdrawal in menstrual period, and serveing on 10 days is a course for the treatment of, treated 3 courses for the treatment of altogether;
(2) matched group: oral ibuprofen slow releasing tablet, 0.3g/ sheet, each 2, sooner or later respectively once.The moon starts to take for premenstrual 5 days, not drug withdrawal in menstrual period, and serveing on 10 days is a course for the treatment of, treats 3 courses for the treatment of altogether.
3, observation of curative effect carries out pain degree judgement and scoring with reference to " new Chinese medicine guideline of clinical investigations "
3.1 dysmenorrhea curative effect index
(1) fully recover: after taking medicine, integration returns to 0 point, stomachache and other transference cures, drug withdrawal 3 non-recidivists of menstrual cycle;
(2) effective: after treatment, integration is down to less than 1/2 of the front integration for the treatment of, and stomachache obviously alleviates, and all the other symptoms take a turn for the better, and refuses to obey that analgesic can adhere to work;
(3) effective: after treatment, integration is down to 1/2 ~ 3/4 of the front integration for the treatment of, and stomachache alleviates, and all the other symptoms take a turn for the better, and taking analgesic can adhere to work;
(4) invalid: stomachache and all the other symptoms are without improver.
3.2 curative effect determinate standard
Integration × 100% before therapeutic index (n)=(before treatment the rear integration of integration-treatment)/treatment
Recovery from illness: n >=90%;
Effective: 70%≤n<90%;
Effective: 30%≤n<70%;
Invalid: n < 30%.
3.3 statistical analysis application SPSS13.0 softwares carry out statistical procedures, data with
represent, enumeration data x
2inspection, measurement data t checks.
3.4 efficacy result
Table 1
| Group | Number of cases | Cure | Effective | Effectively | Invalid | Come off | Effective percentage |
| Treatment group | 58 | 14 | 30 | 11 | 3 | 2 | 94.83% |
| Matched group | 56 | 7 | 21 | 18 | 10 | 4 | 82.14% |
Can be learnt by table 1: treatment group compared with matched group, P<0.05.
Before and after 3.5 liang of group treatments, symptom score is compared
Table 2
| Group | Number of cases | Before treatment | After treatment |
| Treatment group | 58 | 27.63±5.15 | 4.26±2.51 |
| Matched group | 56 | 28.01±5.66 | 10.35±4.98 |
Treatment group: compare before and after treatment P<0.05, has statistical significance; Matched group: compare before and after treatment P<0.05, has statistical significance; After treatment, treatment group is P<0.05 compared with matched group, has statistical significance.
3.6 come off case: treatment group has 2 examples to exit experiment because not taking on time, and matched group has 3 examples not take medicine on time and exit experiment because of digestive tract reaction, 1 example, and all the other all have no adverse reaction.
Detailed description of the invention
Embodiment 1:
Take river Radix Aconiti Lateralis Preparata 5g, Hirudo 2.5g, Radix Bupleuri 2.5g, Rhizoma Zingiberis 2.5g, Cortex Cinnamomi 2.5g, Fructus Foeniculi 5g, Herba Asari 1.25g, Ramulus Cinnamomi 1.25g, Fructus Evodiae 1.25g, Folium Artemisiae Argyi 2.5g, Oletum Trogopterori 2.5g, Rhizoma Corydalis 2.5g, Radix Angelicae Sinensis 5g, Rhizoma Chuanxiong 2.5g, Pollen Typhae 2.5g, Radix Notoginseng 2.5g, Herba Leonuri 5g, Semen Persicae 2.5g, Flos Carthami 2.5g, Radix Paeoniae Alba 2.5g, Rhizoma Cyperi 2.5g, Radix Linderae 2.5g, Rhizoma Curcumae 2.5g, Semen Vaccariae 2.5g, Radix Glycyrrhizae 2.5g, 490g water soaking is added 1 hour after being merged by above-mentioned ladies and gentlemen's medicine, then decoct 1 hour, filter, obtain filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three; Filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20, dries, pulverize, make pill, obtain medicine.
Embodiment 2:
Take river Radix Aconiti Lateralis Preparata 10g, Hirudo 5g, Radix Bupleuri 10g, Rhizoma Zingiberis 5g, Cortex Cinnamomi 1g, Fructus Foeniculi 10g, Herba Asari 1g, Ramulus Cinnamomi 2.5g, Fructus Evodiae 5g, Folium Artemisiae Argyi 5g, Oletum Trogopterori 2.5g, Rhizoma Corydalis 2.5g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 5g, Pollen Typhae 5g, Radix Notoginseng 5g, Herba Leonuri 10g, Semen Persicae 5g, Flos Carthami 5g, Radix Paeoniae Alba 10g, Rhizoma Cyperi 5g, Radix Linderae 5g, Rhizoma Curcumae 5g, Semen Vaccariae 10g, Radix Glycyrrhizae 5g, 1083g water soaking is added 1 hour after being merged by above-mentioned ladies and gentlemen's medicine, then decoct 1 hour, filter, obtain filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three; Filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20, dries, pulverize, make pill, obtain medicine.
Embodiment 3:
Take river Radix Aconiti Lateralis Preparata 15g, Hirudo 1g, Radix Bupleuri 1g, Rhizoma Zingiberis 10g, Cortex Cinnamomi 10g, Fructus Foeniculi 5g, Herba Asari 2g, Ramulus Cinnamomi 2g, Fructus Evodiae 2g, Folium Artemisiae Argyi 10g, Oletum Trogopterori 5g, Rhizoma Corydalis 5g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 4g, Pollen Typhae 10g, Radix Notoginseng 4g, Herba Leonuri 8g, Semen Persicae 8g, Flos Carthami 8g, Radix Paeoniae Alba 5g, Rhizoma Cyperi 8g, Radix Linderae 10g, Rhizoma Curcumae 8g, Semen Vaccariae 8g, Radix Glycyrrhizae 10g, 1370g water soaking is added 1 hour after being merged by above-mentioned ladies and gentlemen's medicine, then decoct 1 hour, filter, obtain filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three; Filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20, dries, pulverize, make pill, obtain medicine.
Embodiment 4:
Take river Radix Aconiti Lateralis Preparata 10g, Hirudo 10g, Radix Bupleuri 5g, Rhizoma Zingiberis 5g, Cortex Cinnamomi 1g, Fructus Foeniculi 10g, Herba Asari 1g, Ramulus Cinnamomi 2.5g, Fructus Evodiae 5g, Folium Artemisiae Argyi 5g, Oletum Trogopterori 10g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 15g, Rhizoma Chuanxiong 5g, Pollen Typhae 5g, Radix Notoginseng 5g, Herba Leonuri 10g, Semen Persicae 5g, Flos Carthami 5g, Radix Paeoniae Alba 1g, Rhizoma Cyperi 5g, Radix Linderae 5g, Rhizoma Curcumae 5g, Semen Vaccariae 10g, Radix Glycyrrhizae 5g, 1088g water soaking is added 1 hour after being merged by above-mentioned ladies and gentlemen's medicine, then decoct 1 hour, filter, obtain filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three; Filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20, dries, pulverize, make pill, obtain medicine.
Embodiment 5:
Take river Radix Aconiti Lateralis Preparata 8g, Hirudo 8g, Radix Bupleuri 5g, Rhizoma Zingiberis 5g, Cortex Cinnamomi 8g, Fructus Foeniculi 15g, Herba Asari 5g, Ramulus Cinnamomi 3g, Fructus Evodiae 3g, Folium Artemisiae Argyi 8g, Oletum Trogopterori 8g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 2.5g, Pollen Typhae 2.5g, Radix Notoginseng 2.5g, Herba Leonuri 5g, Semen Persicae 2.5g, Flos Carthami 4g, Radix Paeoniae Alba 4g, Rhizoma Cyperi 6g, Radix Linderae 6g, Rhizoma Curcumae 4g, Semen Vaccariae 4g, Radix Glycyrrhizae 4g, 1072g water soaking is added 1 hour after being merged by above-mentioned ladies and gentlemen's medicine, then decoct 1 hour, filter, obtain filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three; Filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20, dries, pulverize, make pill, obtain medicine.
Embodiment 6:
Take river Radix Aconiti Lateralis Preparata 8g, Hirudo 8g, Radix Bupleuri 5g, Rhizoma Zingiberis 5g, Cortex Cinnamomi 8g, Fructus Foeniculi 15g, Herba Asari 4g, Ramulus Cinnamomi 4g, Fructus Evodiae 4g, Folium Artemisiae Argyi 6g, Oletum Trogopterori 8g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 2.5g, Pollen Typhae 2.5g, Radix Notoginseng 2.5g, Herba Leonuri 5g, Semen Persicae 6g, Flos Carthami 4g, Radix Paeoniae Alba 4g, Rhizoma Cyperi 6g, Radix Linderae 6g, Rhizoma Curcumae 4g, Semen Vaccariae 4g, Radix Glycyrrhizae 4g, 930g water soaking is added 1 hour after being merged by above-mentioned ladies and gentlemen's medicine, then decoct 1 hour, filter, obtain filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three; Filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20, dries, pulverize, make pill, obtain medicine.
Above-mentioned example is only described, with reference to above-mentioned example and the implementation that can realize the various combination easily seen in conjunction with the aforementioned weight that provides and composition relation thereof a part for each raw material of Chinese medicine weight proportion and components compatibility combination.
Claims (2)
1. treat a medicine for dysmenorrhea, it is characterized in that: it is made by the raw material of Chinese medicine of following weight: river Radix Aconiti Lateralis Preparata 10 parts, Hirudo 5 parts, Radix Bupleuri 5 parts, Rhizoma Zingiberis 5 parts, Cortex Cinnamomi 5 parts, Fructus Foeniculi 10 parts, Herba Asari 2.5 parts, Ramulus Cinnamomi 2.5 parts, Fructus Evodiae 2.5 parts, Folium Artemisiae Argyi 5 parts, Oletum Trogopterori 5 parts, Rhizoma Corydalis 5 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Chuanxiong 5 parts, Pollen Typhae 5 parts, Radix Notoginseng 5 parts, Herba Leonuri 10 parts, 5 parts, Semen Persicae, 5 parts, Flos Carthami, the Radix Paeoniae Alba 5 parts, Rhizoma Cyperi 5 parts, the Radix Linderae 5 parts, Rhizoma Curcumae 5 parts, Semen Vaccariae 5 parts, 5 parts, Radix Glycyrrhizae.
2. a kind of medicine for the treatment of dysmenorrhea according to claim 1, is characterized in that described medicine specifically adopts following step to make:
A takes raw material respectively according to above-mentioned weight proportion, soaks 1 hour after merging, and the addition of described water is 6 ~ 8 times of raw material gross weight, then decocts 1 hour, filters, obtains filtrate one and medicinal residues;
Gained medicinal residues in step a are decocted with water 1 hour by b again, filter, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, leaves standstill, again filter, obtain filtrate three;
Described filtrate three is concentrated into when 60 DEG C of heat are surveyed the thick paste that proportion is 1:20 by c, dries, pulverizes, make pill, obtain medicine.
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| CN103536877B (en) * | 2013-10-18 | 2015-04-29 | 潘曙东 | Traditional Chinese medicine composition for treating dysmenorrheal |
| CN103784881B (en) * | 2014-02-18 | 2018-07-20 | 北京创立科创医药技术开发有限公司 | A kind of Chinese medicine composition and preparation method thereof for treating dysmenorrhoea |
| CN105267906A (en) * | 2014-07-10 | 2016-01-27 | 郑建荣 | Compound chocolate Chinese herbal composition for treating and improving menstrual syndrome of females |
| CN104399024A (en) * | 2014-11-09 | 2015-03-11 | 张鹏 | Traditional Chinese medicine composition for treating dysmenorrheal caused by qi stagnation and blood stasis |
| CN104399023A (en) * | 2014-11-09 | 2015-03-11 | 张鹏 | Traditional Chinese medicine composition for treating dysmenorrheal caused by cold-damp stagnation |
| CN104857397A (en) * | 2015-06-04 | 2015-08-26 | 李永生 | Traditional Chinese medicinal composition for alleviating dysmenorrhea and preparation method for traditional Chinese medicinal composition |
| CN105012601A (en) * | 2015-07-27 | 2015-11-04 | 谢丽蓉 | Traditional Chinese medicine composition for treatment of cold-damp coagulation type dysmenorrhoea |
| CN105194584A (en) * | 2015-11-09 | 2015-12-30 | 孙绪连 | Medicine for treating dysmenorrhea |
| CN105232866A (en) * | 2015-11-18 | 2016-01-13 | 杜英凤 | Traditional Chinese medicine pills for treating dysmenorrhea and preparation method thereof |
| CN105233070A (en) * | 2015-11-18 | 2016-01-13 | 杜英凤 | Traditional Chinese medicine composition for treating dysmenorrhea |
| CN105327253A (en) * | 2015-11-23 | 2016-02-17 | 王平平 | Medicine for treating non-specific ulcerative colitis |
| CN106362134A (en) * | 2016-11-30 | 2017-02-01 | 柳璐 | Traditional Chinese medicine composition for treating gynecologic diseases and preparation method of traditional Chinese medicine composition |
| CN109276701A (en) * | 2018-12-10 | 2019-01-29 | 李天基 | A kind of pharmaceutical composition and preparation method thereof for treating dysmenorrhea |
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| CN103239702A (en) * | 2013-05-24 | 2013-08-14 | 温美珍 | Medicament for treating dysmenorrhea |
| CN103272096A (en) * | 2013-05-29 | 2013-09-04 | 王艳红 | Traditional Chinese medicine for treating dysmenorrhea |
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