CN103461366B - A kind of Pesticidal combination containing CGA 183893 and carbamates - Google Patents
A kind of Pesticidal combination containing CGA 183893 and carbamates Download PDFInfo
- Publication number
- CN103461366B CN103461366B CN201210188737.1A CN201210188737A CN103461366B CN 103461366 B CN103461366 B CN 103461366B CN 201210188737 A CN201210188737 A CN 201210188737A CN 103461366 B CN103461366 B CN 103461366B
- Authority
- CN
- China
- Prior art keywords
- cga
- active component
- pesticidal combination
- mobucin
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention discloses a kind of Pesticidal combination containing CGA 183893 and carbamates, containing active components A and active component B, wherein active components A is selected from CGA 183893, active component B is selected from any one compound following: Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl, and the weight ratio of active components A and active component B is 1 ︰ 70 ~ 50 ︰ 1.The various pests of the present composition to harm agricultural production has synergistic effect, and decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution, to person poultry safety, Environmental compatibility is good, and insect not easily develops immunity to drugs.<!--1-->
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of Pesticidal combination on crop pests containing CGA 183893 and carbamates.
Background technology
CGA 183893 (dicyclanil) chemical name: 4,6-diaminourea-2-cyclopropylamino pyrimidine-5-nitrile, molecular formula: C
8h
10n
6.CGA 183893 interference insect is peeled, and after insect generations Systemic absorption, stops larvae pupation or becomes worm.
Mobucin (isoprocarb) chemical name: o-isopropylphenyl-N-methylcarbamate, molecular formula: C
11h
15nO
2.Mobucin belongs to carbamate insecticide, to insect mainly acetylcholine esterase inhibition, causes insect paralysis to dead.
Meta-tolyl-N-methylcarbamate (MTMC) (metolcarb) chemical name: a tolyl-N-methyl carbamate, molecular formula: C
9h
11nO
2.Meta-tolyl-N-methylcarbamate (MTMC) has tags and fumigation action, and power of knocking down is strong, and the lasting period is short, generally only has 3-4 days, and to rice fulgorid, rice leafhopper and rice thrips, and tea lesser leafhopper etc. has special efficacy.
Chloro-2,3,4a, the 5-tetrahydrochysene-2-of indoxacarb (indoxacarb) chemical name: 7-[methoxycarbonyl (4-Trifluoromethoxyphen-l) carbamoyl] indeno [1,2-e] [1,3,4-] oxadiazines-4a-carboxylate methyl ester, molecular formula: C
22h
17clF
3n
3o
7.Indoxacarb mainly blocks the sodium channel in insect nerve cell, causes target pest to coordinate poor, paralysis, finally dead.Medicament enters polypide by tagging and ingesting, and the behavior of insect changes rapidly, causes insect to stop rapidly ingesting, thus fabulous protects Target crops.Test shows with other insecticide without cross resistance.
Carbaryl (carbaryl) chemical name: 1 naphthyl N methyl carbamate, molecular formula: C
12h
11nO
2.Carbaryl tool broad spectrum activity, suppresses the acetylcholinesterase in pest body, and have favorable effect to insect such as the pink bollworm of leafhopper, plant hopper and biting mouthparts that some are are not easily prevented and treated, insect preventive effect hexachlorcyclohexane, dichlorodiphenyl trichloroethane, parathion etc. having been produced to resistance is good.This medicine toxic action is slow, can be mixed with some organophosphorous pesticides, anti-heterodyne during low temperature.
But in the real process of agricultural production, the problem that pest control the most easily produces is the generation of pest resistance to insecticide.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistant insect.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really has the seldom composite of synergistic effect, especially synergistic effect clearly, very high composite just less of co-toxicity coefficient.Through inventor's research, find CGA 183893 and Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl is composite after can produce good synergistic effect, and not yet open about the relevant report that CGA 183893 and Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl are composite.
Summary of the invention
The object of the invention is to propose a kind ofly have that synergistic function, use cost are low, preventive effect is good containing the Pesticidal combination of CGA 183893 and carbamates.
The Pesticidal combination containing CGA 183893 and carbamates that the present invention proposes contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 70 ~ 50 ︰ 1, described active components A is selected from CGA 183893, active component B is selected from the one in Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl, and active components A and the preferred weight ratio of active component B are 1 ︰ 50 ~ 30 ︰ 1; The weight ratio being more preferably CGA 183893 and Mobucin is 1 ︰ 30 ~ 10 ︰ 1, and the weight ratio of CGA 183893 and meta-tolyl-N-methylcarbamate (MTMC) is 1 ︰ 25 ~ 10 ︰ 1, and the weight ratio of CGA 183893 and indoxacarb is 1 ︰ 20 ~ 20 ︰ 1, and the weight ratio of CGA 183893 and carbaryl is 1 ︰ 30 ~ 10 ︰ 1; The weight ratio most preferably being CGA 183893 and Mobucin is 1 ︰ 20 ~ 5 ︰ 1, and the weight ratio of CGA 183893 and meta-tolyl-N-methylcarbamate (MTMC) is 1 ︰ 15 ~ 5 ︰ 1, and the weight ratio of CGA 183893 and indoxacarb is 1 ︰ 10 ~ 10 ︰ 1, and the weight ratio of CGA 183893 and carbaryl is 1 ︰ 20 ~ 5 ︰ 1.
The Pesticidal combination containing CGA 183893 and carbamates that the present invention proposes is for preventing and treating the purposes of insect on crops.
Described crops comprise cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop.
Described insect comprises rice fulgorid, aphid, cotton bollworm, pink bollworm, trialeurodes vaporariorum, Bemisia tabaci, bridging worm, cabbage caterpillar, oriental tobacco budworm, diamond-back moth, beet armyworm, prodenia litura, apple leaf miner, rice leafhopper, rice leaf roller, thrips.
The weight ratio of active components A, active component B is 1 ︰ 70 ~ 50 ︰ 1.In usual composition, the weight percentage of active component is 0.5% ~ 90% of gross weight, is preferably 5% ~ 80%.According to different preparation types, active component content scope is different.Usually, liquid preparation contains the active substance of by weight 1% ~ 70%, is preferably 5% ~ 50%; Solid pharmaceutical preparation contains the active substance of by weight 5% ~ 80%, is preferably 10% ~ 80%.
At least containing a kind of surfactant in Pesticidal combination of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5% ~ 30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by Pesticidal combination of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, disintegrant known in those skilled in the art, antifreeze etc. can also be contained.
Pesticidal combination of the present invention can by user before use through diluting or directly using.Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active substance, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Pesticidal combination of the present invention, acceptable formulation on any agricultural chemicals can be processed on demand, wherein more preferably formulation is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, can also make microemulsion.
Composition comprises following constituent content when making wetting powder: active components A 1% ~ 50%, active component B1% ~ 70%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, filler surplus.
Composition comprises following constituent content when making water dispersible granules: active components A 1% ~ 50%, active component B1% ~ 70%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Composition comprises following constituent content when making suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, wetting agent 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making suspension emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, solvent 1% ~ 15%, thickener 0 ~ 2%, emulsifier 2% ~ 12%, antifreeze 0 ~ 8%, deionized water add to 100%.
Composition comprises following constituent content when making aqueous emulsion: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, solvent 1% ~ 30%, emulsifier 1% ~ 15%, antifreeze 0 ~ 8%, thickener 0 ~ 2%, defoamer 0.01% ~ 2%, deionized water supply surplus.
Composition comprises following constituent content when making microcapsule suspending agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 10%, organic solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Composition comprises following constituent content when making microcapsule suspension-suspendinagent agent: active components A 0.5% ~ 50%, active component B0.5% ~ 50%, macromolecule cyst material 2% ~ 10%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, organic solvent 1% ~ 15%, emulsifier 1% ~ 6%, defoamer 0.01% ~ 2%, thickener 0 ~ 2%, pH adjusting agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
The invention has the advantages that:
(1) CGA 183893 and Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl composite after, there is obvious synergy and lasting effect; (2) all greater activity is had to cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop insect; (3) decrease pesticide usage amount, reduce the residual quantity of agricultural chemicals on crop, alleviate environmental pollution; (4) to person poultry safety, Environmental compatibility is good; And preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
Below in conjunction with embodiment to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
Application Example one
Example 1 ~ 14 wetting powder
CGA 183893, active component B, dispersant, wetting agent, filler are mixed in mixed cylinder, mixes again after airslide disintegrating mill is pulverized, wetting powder product of the present invention can be obtained, specifically in table 1.
The each component of table 1 embodiment 1 ~ 14 and weight portion
Example 15 ~ 28 water dispersible granules
CGA 183893, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained together the particle diameter needed through air-flow crushing, then add other auxiliary agents such as binding agent (can add and can not add), obtain granulation materials.Item is quantitatively sent in fluidized bed granulating dryer through granulating and after drying, water dispersible granules product of the present invention can being obtained, specifically in table 2.
The each component of table 2 embodiment 15 ~ 28 and weight portion
Example 29 ~ 42 suspending agent
By dispersant, wetting agent, defoamer, thickener (can add and can not add), antifreeze (can add and can not add), mix through high speed shear, add CGA 183893, active component B, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, surplus deionized water is supplied, and can obtain suspending agent product of the present invention, specifically in table 3.
The each component of table 3 embodiment 29 ~ 42 and weight portion
Example 43 ~ 53 suspension emulsion
Dispersant, defoamer, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear, add CGA 183893, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained CGA 183893 suspending agent, then by active component B, solvent, emulsifier and the direct emulsification of various auxiliary agent high speed agitators in suspending agent, surplus deionized water is supplied, obtained suspension emulsion product of the present invention, specifically in table 4,5.
The each component of table 4 embodiment 43 ~ 48 and weight portion
The each component of table 5 embodiment 49 ~ 53 and weight
Example 54 ~ 67 aqueous emulsion
CGA 183893, active component B, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), defoamer are mixed, becomes homogeneous aqueous phase.Under high velocity agitation, aqueous phase is added oil phase, surplus deionized water is supplied; Aqueous emulsion product of the present invention can be obtained, specifically in table 6.
The each component of table 6 embodiment 54 ~ 67 and weight portion
Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl in table 1 ~ 6 are exchanged, can novel formulation be obtained.
Example 68,69 microcapsule suspending agent
By CGA 183893, active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, in a shear condition, oil phase is joined in the aqueous phase solution containing emulsifier, pH adjusting agent, dispersant, surplus deionized water is supplied, bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes the finely disseminated microcapsule suspending agent product of the present composition.Specifically in table 7.
Table 7 embodiment 68,69 each component and weight portion
Example 70,71 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent, make to be dissolved into homogeneous oil phase, oil phase is joined in a shear condition in the aqueous phase solution containing emulsifier, pH adjusting agent, make finely disseminated microcapsule suspending agent.Dispersant, wetting agent, defoamer, thickener (can add and can not add) are mixed through high speed shear, add CGA 183893, ball milling 2 ~ 3 hours in ball mill, make diameter of particle all below 5 μm, obtained suspending agent, then join in the aqueous phase solution of micro-capsule suspension by suspending agent, deionized water supplies surplus, make the finely disseminated microcapsule suspension-suspendinagent agent product of the present composition, specifically in table 8.
Table 8 embodiment 70,71 each component and weight portion
The embodiment of the present invention is the method adopting Toxicity Determination and field trial to combine.First pass through Toxicity Determination, co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC < 80 is antagonism, 80≤CTC≤120 are summation action, CTC > 120 is synergistic effect, on this basis, then carry out field trial.
Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration during test, is placed in beaker respectively for subsequent use.Adopt the method connecing worm after first soaking leaf, take out after the blade of the same size not contacting any medicament is soaked 5s in the liquid configured, naturally dry, put into insect box, then connect for examination larva, raise under 25 DEG C of conditions, often process and repeat for 3 times, often repeating examination borer population used is 50, establishes blank simultaneously, checks dead borer population in 72h, calculate lethality and corrected mortality, try to achieve virulence regression equation and calculate LC
50value.If contrast lethality is greater than 10%, be then considered as invalid test.Computing formula is as follows:
Insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) converts logarithm value to (x), draws virulence regression equation, and calculate the value of often kind of medicament thus with method of least squares, calculates co-toxicity coefficient CTC according to the abundant equation of Sun Yun.Computing formula following (take CGA 183893 as standard agent, its toxicity index is 100):
TI × the P of theoretical toxicity index (the TTI)=CGA 183893 of M
cGA 183893+tI × the P of effective active composition B
effective active composition B
In formula: M is the mixture of different ratio
P
effective active composition Bfor the ratio that effective active composition B is shared in the composition
P
cGA 183893for the ratio that CGA 183893 is shared in the composition
B is selected from the one in Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, carbaryl.
Application Example two:
For examination insect: rice hoppers
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination CGA 183893 and the former medicine of Mobucin and the two different ratio mixture.
Toxicity test result
Table 9 CGA 183893 and the composite toxicity test analysis of results table to rice hoppers of Mobucin
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 1.61 | — |
| Mobucin | — | 9.15 | — |
| Huan Chong Jing ︰ Mobucin | 50:1 | 0.93 | 175.96 |
| Huan Chong Jing ︰ Mobucin | 40:1 | 0.91 | 180.55 |
| Huan Chong Jing ︰ Mobucin | 20:1 | 0.89 | 188.29 |
| Huan Chong Jing ︰ Mobucin | 10:1 | 0.83 | 209.68 |
| Huan Chong Jing ︰ Mobucin | 1:1 | 1.24 | 220.81 |
| Huan Chong Jing ︰ Mobucin | 1:10 | 2.57 | 249.68 |
| Huan Chong Jing ︰ Mobucin | 1:14 | 2.58 | 270.22 |
| Huan Chong Jing ︰ Mobucin | 1:20 | 2.95 | 253.56 |
| Huan Chong Jing ︰ Mobucin | 1:25 | 3.44 | 225.34 |
| Huan Chong Jing ︰ Mobucin | 1:30 | 3.85 | 206.43 |
| Huan Chong Jing ︰ Mobucin | 1:40 | 4.25 | 193.18 |
| Huan Chong Jing ︰ Mobucin | 1:60 | 4.76 | 178.48 |
| Huan Chong Jing ︰ Mobucin | 1:70 | 4.97 | 172.67 |
As shown in Table 9, CGA 183893 and Mobucin to rice hoppers proportioning when 1 ︰ 70 ~ 50 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 70 ~ 50 ︰ 1 scope all shows synergistic effect, when the proportioning of CGA 183893 and Mobucin is at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 205.Testing through applicant the optimum ratio finding CGA 183893 and Mobucin is 10:1,5:1,1:1,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:25,1:30, wherein when CGA 183893 and Mobucin weight ratio are 1:14, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.
Application Example three
For examination insect: rice hoppers
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination CGA 183893 and the former medicine of meta-tolyl-N-methylcarbamate (MTMC) and the two different ratio mixture.
Table 10 CGA 183893 and the composite toxicity test analysis of results table to rice hoppers of meta-tolyl-N-methylcarbamate (MTMC)
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 1.65 | — |
| Meta-tolyl-N-methylcarbamate (MTMC) | — | 8.86 | — |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 50:1 | 0.93 | 180.30 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 40:1 | 0.87 | 193.50 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 20:1 | 0.85 | 201.94 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 10:1 | 0.79 | 225.55 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:1 | 1.17 | 237.78 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:5 | 2.01 | 255.07 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:9 | 2.26 | 272.85 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:15 | 2.71 | 256.83 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:20 | 3.11 | 235.85 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:25 | 3.43 | 221.17 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:35 | 3.95 | 200.05 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:50 | 4.25 | 192.05 |
| Huan Chong Jing ︰ meta-tolyl-N-methylcarbamate (MTMC) | 1:70 | 4.57 | 182.66 |
As shown in Table 10, CGA 183893 and meta-tolyl-N-methylcarbamate (MTMC) to rice hoppers proportioning when 1 ︰ 70 ~ 50 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 70 ~ 50 ︰ 1 scope all shows synergistic effect, when the proportioning of CGA 183893 and meta-tolyl-N-methylcarbamate (MTMC) is at 1 ︰ 25 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 220.Testing through applicant the optimum ratio finding CGA 183893 and meta-tolyl-N-methylcarbamate (MTMC) is 10:1,8:1,5:1,3:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:18,1:20,1:25, wherein when CGA 183893 and meta-tolyl-N-methylcarbamate (MTMC) weight ratio are 1:9, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.
Application Example four
For examination insect: paddy rice rice leaf roller
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination CGA 183893 and the former medicine of indoxacarb and the two different ratio mixture.
Table 11 CGA 183893 and the composite toxicity test analysis of results table to paddy rice rice leaf roller of indoxacarb
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 1.87 | — |
| Indoxacarb | — | 1.95 | — |
| Huan Chong Jing ︰ indoxacarb | 50:1 | 1.02 | 183.48 |
| Huan Chong Jing ︰ indoxacarb | 40:1 | 0.98 | 191.01 |
| Huan Chong Jing ︰ indoxacarb | 30:1 | 0.91 | 205.77 |
| Huan Chong Jing ︰ indoxacarb | 20:1 | 0.82 | 228.49 |
| Huan Chong Jing ︰ indoxacarb | 10:1 | 0.79 | 237.59 |
| Huan Chong Jing ︰ indoxacarb | 5:1 | 0.73 | 257.93 |
| Huan Chong Jing ︰ indoxacarb | 1:1 | 0.68 | 280.76 |
| Huan Chong Jing ︰ indoxacarb | 1:5 | 0.75 | 258.15 |
| Huan Chong Jing ︰ indoxacarb | 1:10 | 0.80 | 242.80 |
| Huan Chong Jing ︰ indoxacarb | 1:20 | 0.86 | 226.28 |
| Huan Chong Jing ︰ indoxacarb | 1:30 | 0.95 | 204.97 |
| Huan Chong Jing ︰ indoxacarb | 1:50 | 1.02 | 191.01 |
| Huan Chong Jing ︰ indoxacarb | 1:70 | 1.08 | 180.44 |
As shown in Table 11, CGA 183893 and indoxacarb to paddy rice rice leaf roller proportioning when 1 ︰ 70 ~ 50 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 70 ~ 50 ︰ 1 scope all shows synergistic effect, when the proportioning of CGA 183893 and indoxacarb is at 1 ︰ 20 ~ 20 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 225.Testing through applicant the optimum ratio finding CGA 183893 and indoxacarb is 20:1,15:1,10:1,5:1,4:1,3:1,2:1,1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:15,1:20, wherein when CGA 183893 and indoxacarb weight ratio are 1:1, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.
Application Example five
For examination insect: cotton cotton bollworm
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: through effective lethal concentration scope of preliminary experiment determination CGA 183893 and the former medicine of carbaryl and the two different ratio mixture.
Table 12 CGA 183893 and the composite toxicity test analysis of results table to cotton cotton bollworm of carbaryl
| Reagent agent | Proportioning | LC 50(ug/mL) | Co-toxicity coefficient (CTC) |
| CGA 183893 | — | 1.82 | — |
| Carbaryl | — | 10.85 | — |
| Huan Chong Jing ︰ carbaryl | 50:1 | 1.05 | 176.21 |
| Huan Chong Jing ︰ carbaryl | 40:1 | 0.98 | 189.56 |
| Huan Chong Jing ︰ carbaryl | 20:1 | 0.95 | 196.86 |
| Huan Chong Jing ︰ carbaryl | 10:1 | 0.89 | 212.93 |
| Huan Chong Jing ︰ carbaryl | 1:1 | 0.85 | 231.64 |
| Huan Chong Jing ︰ carbaryl | 1:10 | 0.86 | 245.71 |
| Huan Chong Jing ︰ carbaryl | 1:15 | 1.17 | 266.43 |
| Huan Chong Jing ︰ carbaryl | 1:20 | 2.38 | 249.56 |
| Huan Chong Jing ︰ carbaryl | 1:25 | 3.12 | 239.70 |
| Huan Chong Jing ︰ carbaryl | 1:30 | 4.12 | 213.06 |
| Huan Chong Jing ︰ carbaryl | 1:40 | 4.89 | 191.31 |
| Huan Chong Jing ︰ carbaryl | 1:60 | 5.27 | 187.67 |
| Huan Chong Jing ︰ carbaryl | 1:70 | 5.87 | 172.80 |
As shown in Table 12, CGA 183893 and carbaryl to cotton cotton bollworm proportioning when 1 ︰ 70 ~ 50 ︰ 1, co-toxicity coefficient is all greater than 120, both explanations mixture in 1 ︰ 70 ~ 50 ︰ 1 scope all shows synergistic effect, when the proportioning of CGA 183893 and carbaryl is at 1 ︰ 30 ~ 10 ︰ 1, synergistic effect is more obviously given prominence to, and co-toxicity coefficient is all greater than 210.Testing through applicant the optimum ratio finding CGA 183893 and carbaryl is 10:1,5:1,1:1,1:3,1:5,1:8,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:25,1:30, wherein when CGA 183893 and carbaryl weight ratio are 1:15, co-toxicity coefficient is maximum, and synergistic effect is the most obvious.
Through test find: CGA 183893 and active component B composite after have obvious synergistic effect to the control of the rice fulgorid in various crop, aphid, cotton bollworm, pink bollworm, trialeurodes vaporariorum, Bemisia tabaci, bridging worm, cabbage caterpillar, oriental tobacco budworm, diamond-back moth, beet armyworm, prodenia litura, apple leaf miner, rice leafhopper, rice leaf roller, thrips, co-toxicity coefficient is all more than 120.
Experimental section:
Test medicine is researched and developed by Shanxi Thompson Biological Technology Co., Ltd., is provided, contrast medicament 20% CGA 183893 suspending agent (autogamy), 20% Mobucin missible oil (commercial), 20% meta-tolyl-N-methylcarbamate (MTMC) missible oil (commercial), 30% indoxacarb water dispersible granule (commercial), 25% carbaryl wetting powder (commercial).
Application Example six CGA 183893 and active component B and compositely prevent and treat the rice hoppers test of pesticide effectiveness
This test arrangement is in Hanzhong City suburb, Shaanxi Province, and investigation rice hoppers insect pest index before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 10 days, 20 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 13 CGA 183893 and active component B and compositely prevent and treat the rice hoppers test of pesticide effectiveness
As can be seen from Table 13, CGA 183893 and active component B composite after effectively can prevent and treat rice hoppers, through inventor test prove CGA 183893 and active component B composite after also effectively can prevent and treat rice leaf roller.Control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example seven CGA 183893 and active component B and the composite control cucumber trialeurodes vaporariorum test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation cucumber trialeurodes vaporariorum insect pest index before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 10 days, 20 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 14 CGA 183893 and active component B and the composite control cucumber trialeurodes vaporariorum test of pesticide effectiveness thereof
As can be seen from Table 14, CGA 183893 and active component B composite after can effectively prevent and treat cucumber trialeurodes vaporariorum, through inventor test prove CGA 183893 and active component B composite after also effectively can prevent and treat Bemisia tabaci.Control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight CGA 183893 and active component B and the composite control wild cabbage diamond-back moth test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation wild cabbage diamond-back moth insect pest index before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 15 days, 30 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 15 CGA 183893 and active component B and the composite control wild cabbage diamond-back moth test of pesticide effectiveness thereof
As can be seen from Table 15, CGA 183893 and active component B and composite control wild cabbage diamond-back moth thereof, through inventor test prove CGA 183893 and active component B composite after also effectively can prevent and treat beet armyworm.Control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine CGA 183893 and active component B and the composite control cotton cotton bollworm test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation cotton cotton bollworm insect pest index before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 7 days, 15 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 16 CGA 183893 and active component B and the composite control cotton cotton bollworm test of pesticide effectiveness thereof
As can be seen from Table 16, CGA 183893 and active component B composite after can effectively prevent and treat cotton cotton bollworm, through inventor test prove CGA 183893 and active component B composite after also effectively can prevent and treat pink bollworm.Control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten CGA 183893 and active component B and the composite control tobacco oriental tobacco budworm test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and the blue or green pests index of investigation tobacco smoke before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 10 days, 20 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 17 CGA 183893 and active component B and the composite control tobacco oriental tobacco budworm test of pesticide effectiveness thereof
As can be seen from Table 17, CGA 183893 and active component B composite after can effectively prevent and treat tobacco oriental tobacco budworm, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 11 CGA 183893 and active component B and the composite control cucumber prodenia litura test of pesticide effectiveness thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation brassicaceous vegetable cabbage caterpillar insect pest index before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 10 days, 20 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 18 CGA 183893 and active component B and the composite control cucumber prodenia litura test of pesticide effectiveness thereof
As can be seen from Table 18, CGA 183893 and active component B composite after can effectively prevent and treat cucumber prodenia litura, control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example 12 CGA 183893 and active component B and composite control rose Control of Aphids thereof
This test arrangement is at Xian District, Shanxi Province suburban area, and investigation rose aphid insect pest index before medicine, in the dispenser of insect pest initial stage of origination, 3 days, 15 days, 30 days investigation insect pest indexes after dispenser also calculate preventive effect.Result of the test is as follows:
Table 19 CGA 183893 and active component B and composite control rose Control of Aphids thereof
As can be seen from Table 19, CGA 183893 and active component B composite after can effectively prevent and treat rose aphid, through inventor test prove CGA 183893 and active component B composite after also effectively can prevent and treat thrips.Control efficiency is all better than the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, CGA 183893 and Mobucin, meta-tolyl-N-methylcarbamate (MTMC), indoxacarb, the composite rear preventive effect to common insect pests such as the rice fulgorid in various crop, aphid, cotton bollworm, pink bollworm, trialeurodes vaporariorum, Bemisia tabaci, bridging worm, cabbage caterpillar, oriental tobacco budworm, diamond-back moth, beet armyworm, prodenia litura, apple leaf miner, rice leafhopper, rice leaf roller, thrips of carbaryl are all more than 95%, be better than single dose preventive effect, synergistic effect is obvious.
Claims (5)
1. one kind contains the Pesticidal combination of CGA 183893 and carbamates, containing active components A and active component B, it is characterized in that: active components A and active component B weight ratio are 1 ︰ 70 ~ 50 ︰ 1, and described active components A is CGA 183893, and active component B is Mobucin.
2. the Pesticidal combination containing CGA 183893 and carbamates according to claim 1, is characterized in that: the weight ratio of active components A and active component B is 1 ︰ 50 ~ 30 ︰ 1.
3. the Pesticidal combination containing CGA 183893 and carbamates according to claim 2, is characterized in that: the weight ratio of CGA 183893 and Mobucin is 1 ︰ 30 ~ 10 ︰ 1.
4. the Pesticidal combination containing CGA 183893 and carbamates according to any one of claim 1 to 3, is characterized in that: composition makes wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent, microemulsion.
5. the Pesticidal combination containing CGA 183893 and carbamates according to claim 4 is for preventing and treating the purposes of rice fulgorid on crops, aphid, cotton bollworm, pink bollworm, trialeurodes vaporariorum, Bemisia tabaci, bridging worm, cabbage caterpillar, oriental tobacco budworm, diamond-back moth, beet armyworm, prodenia litura, apple leaf miner, rice leafhopper, rice leaf roller, thrips.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210188737.1A CN103461366B (en) | 2012-06-09 | 2012-06-09 | A kind of Pesticidal combination containing CGA 183893 and carbamates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210188737.1A CN103461366B (en) | 2012-06-09 | 2012-06-09 | A kind of Pesticidal combination containing CGA 183893 and carbamates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103461366A CN103461366A (en) | 2013-12-25 |
| CN103461366B true CN103461366B (en) | 2015-10-28 |
Family
ID=49786608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210188737.1A Expired - Fee Related CN103461366B (en) | 2012-06-09 | 2012-06-09 | A kind of Pesticidal combination containing CGA 183893 and carbamates |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103461366B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104285999A (en) * | 2014-10-15 | 2015-01-21 | 济南凯因生物科技有限公司 | Insecticidal composition for preventing and treating beet plutella xylostella |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009118312A1 (en) * | 2008-03-28 | 2009-10-01 | Novartis Ag | Dicyclanil formulation |
| CN102113496A (en) * | 2010-01-03 | 2011-07-06 | 青岛海利尔药业有限公司 | Bactericidal composition containing dicyclanil and methomyl |
-
2012
- 2012-06-09 CN CN201210188737.1A patent/CN103461366B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009118312A1 (en) * | 2008-03-28 | 2009-10-01 | Novartis Ag | Dicyclanil formulation |
| CN102113496A (en) * | 2010-01-03 | 2011-07-06 | 青岛海利尔药业有限公司 | Bactericidal composition containing dicyclanil and methomyl |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103461366A (en) | 2013-12-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103563901B (en) | A kind of Efficient insecticidal composition containing propylene glycol alginate | |
| CN103563950B (en) | Pesticide composition | |
| CN104115845A (en) | Efficient pesticide composition containing flubendiamide | |
| CN103563962B (en) | A kind of Pesticidal combination containing propylene glycol alginate and anabasine | |
| CN103960280A (en) | High-efficiency insecticidal composition containing tetrachlorantraniliprole | |
| CN103651403B (en) | A kind of Efficient insecticidal composition containing Spiromesifen | |
| CN103651363B (en) | Pesticidal composition containing spiromesifen and nereistoxin | |
| CN103931641A (en) | Insecticidal composition containing silvchongxian'an and carbamate | |
| CN103461366B (en) | A kind of Pesticidal combination containing CGA 183893 and carbamates | |
| CN103651548B (en) | A kind of Pesticidal combination containing Spiromesifen | |
| CN103563956B (en) | Insecticidal composition containing propylene glycol alginate and carbamates | |
| CN104106587A (en) | Insecticidal composition containing flubendiamide and carbamate | |
| CN103651488A (en) | Pesticide composition containing fluorin pyrazol furan ketone and carbamates | |
| CN103416430B (en) | A kind of composition pesticide | |
| CN104115830A (en) | Insecticidal composition containing flubendiamide and nereistoxin | |
| CN103651484B (en) | Pesticide composition containing spiromesifen and carbamates | |
| CN105104383A (en) | Efficient insecticide composition containing spiromesifen | |
| CN103478157B (en) | A kind of Efficient insecticidal composition | |
| CN102696644A (en) | Insecticidal composition containing bromantraniliprole and carbamates | |
| CN103858925B (en) | A kind of Pesticidal combination containing carbosulfan and diazinon | |
| CN103563977B (en) | Pesticide pest-killing composition containing propylene glycol alginate | |
| CN103416420B (en) | A kind of Pesticidal combination containing CGA 183893 | |
| CN104430429A (en) | Insecticidal composition containing trifluorobenzene pyrimidine and carbamates | |
| CN103503876A (en) | Insecticidal composition containing bromantraniliprole and nereistoxin | |
| CN103416406B (en) | A kind of Pesticidal combination containing CGA 183893 and neires toxin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wu Yanxin Inventor after: Wu Fengcheng Inventor after: Wu Yanhui Inventor before: Zhang Qiufang |
|
| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170817 Address after: 419200 Hunan Huaihua Xinhuang County Industrial Concentration Area Patentee after: Hunan shunxinlong Chen Biological Engineering Co. Ltd. Address before: 715500 Pucheng, Shaanxi, North Ring Road, Central Patentee before: Shanxi Thompson Biological Technology Co., Ltd. |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151028 Termination date: 20180609 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |