CN103446327A - Antianemic oral liquid and preparation technology thereof - Google Patents
Antianemic oral liquid and preparation technology thereof Download PDFInfo
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- CN103446327A CN103446327A CN2013103632780A CN201310363278A CN103446327A CN 103446327 A CN103446327 A CN 103446327A CN 2013103632780 A CN2013103632780 A CN 2013103632780A CN 201310363278 A CN201310363278 A CN 201310363278A CN 103446327 A CN103446327 A CN 103446327A
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Abstract
The invention relates to an antianemic oral liquid and a preparation technology thereof. The antianemic oral liquid is prepared from the following components in parts by weight: 90-115 parts of donkey-hide gelatin, 5-10 parts of ginseng, 210-235 parts of prepared rehmannia root, 155-170 parts of codonopsis pilosula, 10-30 parts of fructus momordicae extract, and 3-7 parts of grain fennel extract. By adopting the preparation technology, two natural plants of momordica grosvenori and grain fennel are introduced to achieve the sugar-free and natural antiseptic preservative effects of the oral liquid; the defects that the antianemic oral liquid is not suitable for being taken by patients with diabetes mellitus and hyperglycemia, and organic preservatives are directly mixed in the prior art are overcome. By adopting the preparation technology of the antianemic oral liquid disclosed by the invention, loss of effective ingredients of each component is prevented to the maximal extent.
Description
Technical field
The present invention relates to a kind of anti-anemia oral liquid and preparation technology thereof.
Background technology
The preparation method that April 5 calendar year 2001 is bulletin, Chinese invention patent that notification number is CN 1064849C discloses a kind of medicament of enriching blood, effect is remarkable enriching blood, aspect QI invigorating for this medicament of enriching blood, but its prescription contains sucrose and organic anti-corrosive agent, make diabetes and hyperglycemic patients to apply, limited greatly the quantity of its applicable colony, organic anti-corrosive agent is simultaneously directly added in the oral medicine leaf, can affect largely its advantage in health care and health preserving field as the nutriment of enriching blood.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect that how to overcome prior art, and a kind of anti-anemia oral liquid and preparation technology thereof are provided.
For solving the problems of the technologies described above, this kind of anti-anemia oral liquid is characterized in that: have following component according to shown in weight ratio be prepared from,
As preferably, this oral liquid by following component according to shown in weight ratio be prepared from,
As further preferably, this oral liquid by following component according to shown in weight ratio be prepared from,
Described Fructus Momordicae extract is full berry extract.
The fragrant extract of described Fructus Foeniculi is the fruit leaf extract.
The preparation technology of this anti-anemia oral liquid comprises the following steps:
Step 1): feeding
By above-mentioned weight ratio, take each component;
Step 2): medicine juice extracts for the first time
The Radix Ginseng that to obtain through step 1), Radix Rehmanniae Preparata, Radix Codonopsis, the fragrant extract of Fructus Foeniculi add in the multipotency Chinese medicament extracting device, then add water 6000kg, soak 3～5h; Medical material heating after soaking, straight gas and interlayer heat simultaneously, and pressure is less than or equal to 0.1MPa, after boiling, closes straight gas, continues to pass into jacket steam, after heated and boiled to medicine juice proportion reaches 1.04, emits medicine juice for the first time;
Step 3): medicine juice extracts for the second time
Add for the second time water 4000kg in the multipotency Chinese medicament extracting device, heated and boiled, after reaching 1.01 to medicine juice proportion, emit medicine juice for the second time;
Step 4): medicine juice extracts for the third time
Add for the third time water 2000kg in the multipotency Chinese medicament extracting device, heated and boiled, after reaching 1.005 to medicine juice proportion, emit medicine juice for the third time;
Step 5): medicine juice mixes and separates with medicinal residues
Will be through step 2), 3), 4) obtain three medicine juice and squeeze into seperator with pump and separated, before separating, the medicinal liquid funnel adds a gauze layer, separating rate must not be greater than 16kg/, every 30min does deslagging one time;
Step 6): medicine juice evaporation purification
When triple effect vacuum machine is opened vacuum, when triple effect vacuum reaches 0.06MPa, the medicine juice that will obtain through step 5) sucks in triple effect evaporator and evaporates by vacuum, after being evaporated to medicinal liquid proportion and reaching between 1.05-1.06, emits medicine juice;
Step 7): Colla Corii Asini dissolves in
The Colla Corii Asini that half is obtained by step 1) and 5 times are to the water of this Colla Corii Asini weight, add in jacketed pan, after being heated to boiling, the Colla Corii Asini that second half is obtained by step 1) adds constantly stirring in pot, after Colla Corii Asini dissolves into uniform glue, add the Fructus Momordicae extract of being obtained by step 1), continue to stir, and turn glue foam and impurity Ex-all with foam;
Step 8): medicine juice, glue juice mix and deslagging
By step 6) gained medicine juice and the 7th) gained glue juice, squeeze into pump in the settling box with heating function, slowly add sodium carbonate liquor that pH is adjusted to 5.5～6.5, heated and boiled 20～30min, standing 24 hours, then the admixing medical solutions after precipitation is separated with seperator, every 30min does deslagging one time, after mixing the separation fully of melt cinder liquid, add turnover barrel, carry out fine straining, pressure is no more than 0.1MPa, and the medicinal liquid after fine straining enters liquid receiver;
Step 9): sieving fill
To through the medicinal liquid of step 6) gained in liquid receiver suction concentration pan, be evaporated to relative density more than 1.085 with vacuum pump, pH value 4.5-6.5, be heated to boil, and 100 ℃ are boiled 15min; Finally medicinal liquid is squeezed into pump in the finished product liquid receiver that is provided with 200 order sieves, covered and enclosed, be no more than 6h standing time, fill, and sterilizing obtains this anti-anemia oral liquid.
The anti-anemia oral liquid of the present invention utilizes Fructus Momordicae as main flavoring agent, its fruit extract is a kind of sweeting agent of low in calories, high sugariness, its sugariness under equal in quality can reach glucose or sucrose 20 times, and its contained heat only has the two 1/50th, coordinate the fragrant extract of Fructus Foeniculi auxiliary it, not only make diabetes and hyperglycemic patients relievedly take, and Fructus Foeniculi perfume (or spice) can be eliminated the stench flavor of Colla Corii Asini to a certain extent; Fructus Momordicae and Fructus Foeniculi perfume (or spice) all have strengthening the spleen and stomach, absorbefacient effect simultaneously, can greatly alleviate Colla Corii Asini and grow greasy defect; Fructus Momordicae or a kind of antiseptic of pure natural in addition.
The anti-anemia oral liquid of the present invention especially is applicable to taking with diabetes and hyperglycemic patients.
The preparation technology of the anti-anemia oral liquid of the present invention, take the repeatedly extraction of minute condition to the medicine juice raw material, and medicine juice, glue juice extract respectively the process of rear mixing, makes to the full extent the effective ingredient of each component not run off.
The specific embodiment
Embodiment 1: the preparation technology of this anti-anemia oral liquid comprises the following steps:
Step 1): by following component and quality feeding
Step 2): medicine juice extracts for the first time
The Radix Ginseng that to obtain through step 1), Radix Rehmanniae Preparata, Radix Codonopsis, the fragrant extract of Fructus Foeniculi add in the multipotency Chinese medicament extracting device, then add water 6000kg, soak 3～5h; Medical material heating after soaking, straight gas and interlayer heat simultaneously, and pressure is less than or equal to 0.1MPa, after boiling, closes straight gas, continues to pass into jacket steam, after heated and boiled to medicine juice proportion reaches 1.04, emits medicine juice for the first time;
Step 3): medicine juice extracts for the second time
Add for the second time water 4000kg in the multipotency Chinese medicament extracting device, heated and boiled, after reaching 1.01 to medicine juice proportion, emit medicine juice for the second time;
Step 4): medicine juice extracts for the third time
Add for the third time water 2000kg in the multipotency Chinese medicament extracting device, heated and boiled, after reaching 1.005 to medicine juice proportion, emit medicine juice for the third time;
Step 5): medicine juice mixes and separates with medicinal residues
Will be through step 2), 3), 4) obtain three medicine juice and squeeze into seperator with pump and separated, before separating, the medicinal liquid funnel adds a gauze layer, separating rate must not be greater than 16kg/, every 30min does deslagging one time;
Step 6): medicine juice evaporation purification
When triple effect vacuum machine is opened vacuum, when triple effect vacuum reaches 0.06MPa, the medicine juice that will obtain through step 5) sucks in triple effect evaporator and evaporates by vacuum, after being evaporated to medicinal liquid proportion and reaching between 1.05-1.06, emits medicine juice;
Step 7): Colla Corii Asini dissolves in
The Colla Corii Asini that half is obtained by step 1) and 5 times are to the water of this Colla Corii Asini weight, add in jacketed pan, after being heated to boiling, the Colla Corii Asini that second half is obtained by step 1) adds constantly stirring in pot, after Colla Corii Asini dissolves into uniform glue, add the Fructus Momordicae extract of being obtained by step 1), continue to stir, and turn glue foam and impurity Ex-all with foam;
Step 8): medicine juice, glue juice mix and deslagging
By step 6) gained medicine juice and the 7th) gained glue juice, squeeze into pump in the settling box with heating function, slowly add sodium carbonate liquor that pH is adjusted to 5.5～6.5, heated and boiled 20～30min, standing 24 hours, then the admixing medical solutions after precipitation is separated with seperator, every 30min does deslagging one time, after mixing the separation fully of melt cinder liquid, add turnover barrel, carry out fine straining, pressure is no more than 0.1MPa, and the medicinal liquid after fine straining enters liquid receiver;
Step 9): sieving fill
To through the medicinal liquid of step 6) gained in liquid receiver suction concentration pan, be evaporated to relative density more than 1.085 with vacuum pump, pH value 4.5-6.5, be heated to boil, and 100 ℃ are boiled 15min; Finally medicinal liquid is squeezed into pump in the finished product liquid receiver that is provided with 200 order sieves, covered and enclosed, be no more than 6h standing time, fill, and sterilizing obtains this anti-anemia oral liquid A.
Embodiment 2: the preparation technology of this anti-anemia oral liquid comprises the following steps:
Step 1): by following component and quality feeding
Step 2) operate as described in Example 1 to step 9), obtain this anti-anemia oral liquid B.Embodiment 3: the preparation technology of this anti-anemia oral liquid comprises the following steps:
Step 1): by following component and quality feeding
Step 2) operate as described in Example 1 to step 9), obtain this anti-anemia oral liquid C.Embodiment 4: the preparation technology of this anti-anemia oral liquid comprises the following steps:
Step 1): by following component and quality feeding
Step 2) operate as described in Example 1 to step 9), obtain this anti-anemia oral liquid B.
Embodiment 5: the preparation technology of this anti-anemia oral liquid comprises the following steps:
Step 1): by following component and quality feeding
Step 2) operate as described in Example 1 to step 9), obtain this anti-anemia oral liquid E.
The present invention includes but be not limited to above-mentioned embodiment, any product that meets the description of these claims, within all falling into protection scope of the present invention.
Claims (4)
1. an anti-anemia oral liquid is characterized in that: this oral liquid by following component according to shown in weight ratio be prepared from,
2. anti-anemia oral liquid according to claim 1 is characterized in that: this oral liquid by following component according to shown in weight ratio be prepared from,
3. anti-anemia oral liquid according to claim 1 is characterized in that: this oral liquid by following component according to shown in weight ratio be prepared from,
4. the preparation technology of an anti-anemia oral liquid, it is characterized in that: this preparation technology comprises the following steps:
Step 1): feeding
By the arbitrary described weight ratio of claim 1-4, take each component;
Step 2): medicine juice extracts for the first time
The Radix Ginseng that to obtain through step 1), Radix Rehmanniae Preparata, Radix Codonopsis, the fragrant extract of Fructus Foeniculi add in the multipotency Chinese medicament extracting device, then add water 6000kg, soak 3～5h; Medical material heating after soaking, straight gas and interlayer heat simultaneously, and pressure is less than or equal to 0.1MPa, after boiling, closes straight gas, continues to pass into jacket steam, after heated and boiled to medicine juice proportion reaches 1.04, emits medicine juice for the first time;
Step 3): medicine juice extracts for the second time
Add for the second time water 4000kg in the multipotency Chinese medicament extracting device, heated and boiled, after reaching 1.01 to medicine juice proportion, emit medicine juice for the second time;
Step 4): medicine juice extracts for the third time
Add for the third time water 2000kg in the multipotency Chinese medicament extracting device, heated and boiled, after reaching 1.005 to medicine juice proportion, emit medicine juice for the third time;
Step 5): medicine juice mixes and separates with medicinal residues
Will be through step 2), 3), 4) obtain three medicine juice and squeeze into seperator with pump and separated, before separating, the medicinal liquid funnel adds a gauze layer, separating rate must not be greater than 16kg/, every 30min does deslagging one time;
Step 6): medicine juice evaporation purification
When triple effect vacuum machine is opened vacuum, when triple effect vacuum reaches 0.06 MPa, the medicine juice that will obtain through step 5) sucks in triple effect evaporator and evaporates by vacuum, after being evaporated to medicinal liquid proportion and reaching between 1.05-1.06, emits medicine juice;
Step 7): Colla Corii Asini dissolves in
The Colla Corii Asini that half is obtained by step 1) and 5 times are to the water of this Colla Corii Asini weight, add in jacketed pan, after being heated to boiling, the Colla Corii Asini that second half is obtained by step 1) adds constantly stirring in pot, after Colla Corii Asini dissolves into uniform glue, add the Fructus Momordicae extract of being obtained by step 1), continue to stir, and turn glue foam and impurity Ex-all with foam;
Step 8): medicine juice, glue juice mix and deslagging
By step 6) gained medicine juice and the 7th) gained glue juice, squeeze into pump in the settling box with heating function, slowly add sodium carbonate liquor that pH is adjusted to 5.5～6.5, heated and boiled 20～30min, standing 24 hours, then the admixing medical solutions after precipitation is separated with seperator, every 30min does deslagging one time, after mixing the separation fully of melt cinder liquid, add turnover barrel, carry out fine straining, pressure is no more than 0.1MPa, and the medicinal liquid after fine straining enters liquid receiver;
Step 9): sieving fill
To through the medicinal liquid of step 6) gained in liquid receiver suction concentration pan, be evaporated to relative density more than 1.085 with vacuum pump, pH value 4.5-6.5, be heated to boil, and 100 ℃ are boiled 15min; Finally medicinal liquid is squeezed into pump in the finished product liquid receiver that is provided with 200 order sieves, covered and enclosed, be no more than 6h standing time, fill, and sterilizing obtains this anti-anemia oral liquid.
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| CN2013103632780A CN103446327A (en) | 2013-08-20 | 2013-08-20 | Antianemic oral liquid and preparation technology thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109692A (en) * | 2016-08-26 | 2016-11-16 | 山东东阿东盛阿胶产品科技开发有限公司 | A kind of Colla Corii Asini panax ginseng and campanumaea pilosula rehmannia-root oral liquid and preparation method thereof |
| CN106309839A (en) * | 2016-08-26 | 2017-01-11 | 山东东阿东盛阿胶产品科技开发有限公司 | Compound donkey-hide gelatin oral liquid with effects of helping digestion and invigorating stomach and preparation method thereof |
| CN111557367A (en) * | 2020-05-28 | 2020-08-21 | 辽宁鑫健林国医堂健康管理有限公司 | Preparation method of microbial fermentation tabletting candy with heart blood supply regulating function |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1168805A (en) * | 1997-06-20 | 1997-12-31 | 山东东阿阿胶股份有限公司 | Medicine for enriching the blood |
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2013
- 2013-08-20 CN CN2013103632780A patent/CN103446327A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1168805A (en) * | 1997-06-20 | 1997-12-31 | 山东东阿阿胶股份有限公司 | Medicine for enriching the blood |
Non-Patent Citations (2)
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|---|
| 付起凤等: "小茴香化学成分及药理作用的研究进展", 《中医药信息》, vol. 25, no. 5, 31 December 2008 (2008-12-31) * |
| 陈笛华等: "罗汉果的药用与甜味", 《天然产物研究与开发》, no. 1, 31 December 1992 (1992-12-31), pages 38 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106109692A (en) * | 2016-08-26 | 2016-11-16 | 山东东阿东盛阿胶产品科技开发有限公司 | A kind of Colla Corii Asini panax ginseng and campanumaea pilosula rehmannia-root oral liquid and preparation method thereof |
| CN106309839A (en) * | 2016-08-26 | 2017-01-11 | 山东东阿东盛阿胶产品科技开发有限公司 | Compound donkey-hide gelatin oral liquid with effects of helping digestion and invigorating stomach and preparation method thereof |
| CN111557367A (en) * | 2020-05-28 | 2020-08-21 | 辽宁鑫健林国医堂健康管理有限公司 | Preparation method of microbial fermentation tabletting candy with heart blood supply regulating function |
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Application publication date: 20131218 |