Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a dried poultry egg capable of preventing alcoholic liver injury, which is prepared by taking whole egg liquid of the poultry egg as a main raw material. The food also contains various components for relieving alcoholism and protecting liver, and can be processed into dish with delicate appearance, such as cold dish, so that people can also achieve the aim of relieving alcoholism and protecting liver during the process of enjoying delicious food with meals.
In order to solve the technical problems, the invention adopts the following technical means:
a dried poultry egg capable of preventing alcoholic liver injury is characterized in that: the feed is prepared from the following raw materials in parts by weight: 800-900 parts of whole egg liquid of eggs, 20-40 parts of bruised ginger, 25-30 parts of flower of kudzuvine root, 5-10 parts of white paeony root, 3-5 parts of tsaoko amomum fruit, 5-10 parts of ginseng, 20-25 parts of poria cocos, 20-30 parts of arillus longan, 5-10 parts of medlar, 10-15 parts of carapace and 20-40 parts of seasoning.
The preparation method of the dried poultry egg capable of preventing alcoholic liver injury comprises the following steps:
(1) weighing the raw materials in parts by weight;
(2) respectively carrying out superfine grinding on the weighed ginger powder, the longan pulp, the medlar and the carapace to 100-mesh and 200-mesh powder, and mixing and stirring uniformly to obtain traditional Chinese medicine powder;
(3) decocting the weighed white paeony root, the tsaoko amomum fruit, the kudzuvine root flower, the ginseng and the tuckahoe with water twice, each time for 2 hours, filtering, combining the filtrates, standing for 24 hours, taking supernatant fluid, concentrating the supernatant fluid under reduced pressure into clear paste, uniformly mixing the clear paste with the traditional Chinese medicine powder obtained in the step (2), and then carrying out vacuum freeze drying on the mixture, and crushing the mixture into 100-mesh and 120-mesh traditional Chinese medicine fine powder;
(4) weighing whole egg liquid of the poultry eggs, seasonings and the traditional Chinese medicine fine powder obtained in the step (3), uniformly stirring in a container, slowly heating in the stirring process, keeping the constant temperature when the temperature is raised to 60-70 ℃, and continuously and slowly stirring to obtain mixed egg liquid;
(5) pouring the mixed egg liquid obtained in the step (4) into a non-stick mold, steaming with steam, and forming;
(6) packaging, sterilizing and inspecting.
Preferably, the dried poultry egg capable of preventing alcoholic liver injury is prepared from the following raw materials in parts by weight: 850 parts of whole egg liquid of poultry eggs, 30 parts of bruised ginger, 28 parts of flower of kudzuvine root, 8 parts of white paeony root, 4 parts of tsaoko amomum fruit, 8 parts of ginseng, 22 parts of tuckahoe, 25 parts of longan pulp, 7 parts of medlar, 12 parts of carapace and 30 parts of seasoning.
The seasoning is one or more selected from salt, chicken essence, white granulated sugar, chili powder, pepper powder, cinnamon and aniseed, and the seasoning can be matched and combined randomly according to personal taste.
The poultry egg is preferably one or more of egg, duck egg, goose egg and quail egg.
In addition, the cooked and formed dried poultry eggs can be baked or marinated according to the flavor and the market demand, so that dried poultry eggs with different flavors can be obtained.
The eating method of the dried poultry egg comprises the following steps: directly cutting into cold dish, for example, cutting into thread, sheet or block; in addition, the product can also be used as main material or auxiliary material for stir-frying and stewing.
The dried poultry egg of the invention has the following advantages and beneficial effects:
firstly, the invention combines a plurality of Chinese herbal medicine components and uses the Chinese herbal medicine components for producing the dried poultry eggs, so that the dried poultry eggs have the effects of dispelling the effects of alcohol, protecting the liver and preventing alcoholic liver injury, can be conveniently eaten as dishes, effectively solves the problem that the existing sobering-up drugs need to be eaten independently before or after meals, has good product flavor and is popular with consumers due to the specific proportion and formula, and can avoid liver injury caused by drinking while enjoying delicious food, thereby having wide market prospect.
Secondly, the pueraria flower selected by the invention has the functions of relieving alcoholism and activating spleen, the water extract of the pueraria flower reduces the concentration of ethanol by activating the activity of alcohol dehydrogenase, and has a protection effect on liver cell damage caused by alcohol, the effective components of the pueraria flower have an improvement effect on alcohol metabolic disturbance and liver function, and also have a certain effect on organ disturbance and digestive tract dysfunction caused by alcohol; radix Paeoniae alba has effects of replenishing blood, softening liver, suppressing hyperactive liver and relieving pain; the ginseng can greatly tonify primordial qi, recover pulse, relieve depletion, tonify spleen, benefit lung, promote salivation to quench thirst, calm nerves and benefit intelligence; the tuckahoe has mild drug property, can remove dampness without damaging vital qi, can relax smooth muscles of digestive tracts, inhibit gastric acid secretion, prevent hepatocyte necrosis, has antibacterial effect and the like; the lycium barbarum polysaccharide has the effects of promoting immunity, resisting aging, resisting tumors, eliminating free radicals, resisting fatigue, resisting radiation, protecting liver, protecting and improving reproductive function and the like; the chitosan in the carapace can enhance the liver function and obviously accelerate the alcohol metabolism, not only can reduce the concentration of ethanol, but also can prevent the formation of fatty liver and liver cirrhosis because the ethanol is processed in time; the addition of the arillus longan and the amomum tsao-ko can reduce the medicinal taste brought by the addition of the Chinese herbal medicines and improve the mouthfeel of the dried poultry eggs. The mutual compatibility of the traditional Chinese medicine components greatly plays a role in preventing alcoholic liver injury on one hand, and in addition, the formula and the proportion are adopted, so that good flavor and taste are achieved.
Thirdly, according to the property difference and the distribution of the effective components of the traditional Chinese medicinal materials, the invention adopts different processing modes, the bruised ginger, the arillus longan, the medlar and the carapace are added in a powder form, the white paeony root, the tsaoko amomum fruit, the pueraria flower, the ginseng and the tuckahoe are added in a mode of extracting the effective components by water decoction, and the granularity of 100 plus 120 meshes is adopted, thereby ensuring good taste.
In a word, the product of the invention not only has good taste, but also has good effect of preventing alcoholic liver injury, so that people can enjoy delicious food and avoid liver injury caused by drinking, and the product is expected to become a popular dish on a dining table and has wide market prospect.
Detailed Description
Example 1: a dried poultry egg capable of preventing alcoholic liver injury is prepared from the following raw materials in parts by weight: 850 parts of whole egg liquid of poultry eggs, 30 parts of bruised ginger, 28 parts of flower of kudzuvine root, 8 parts of white paeony root, 4 parts of tsaoko amomum fruit, 8 parts of ginseng, 22 parts of tuckahoe, 25 parts of longan pulp, 7 parts of medlar, 12 parts of carapace and 30 parts of seasoning. The preparation method comprises the following steps:
(1) weighing the raw materials in parts by weight;
(2) respectively carrying out superfine grinding on the weighed ginger powder, the longan pulp, the medlar and the carapace to 100-mesh and 200-mesh powder, and mixing and stirring uniformly to obtain traditional Chinese medicine powder;
(3) decocting the weighed white paeony root, the tsaoko amomum fruit, the kudzuvine root flower, the ginseng and the tuckahoe with water twice, each time for 2 hours, filtering, combining the filtrates, standing for 24 hours, taking supernatant fluid, concentrating the supernatant fluid under reduced pressure into clear paste, uniformly mixing the clear paste with the traditional Chinese medicine powder obtained in the step (2), and then carrying out vacuum freeze drying on the mixture, and crushing the mixture into 100-mesh and 120-mesh traditional Chinese medicine fine powder;
(4) weighing whole egg liquid of the poultry eggs, seasonings and the traditional Chinese medicine fine powder obtained in the step (3), uniformly stirring in a container, slowly heating in the stirring process, keeping the constant temperature when the temperature is raised to 60-70 ℃, and continuously and slowly stirring to obtain mixed egg liquid;
(5) pouring the mixed egg liquid obtained in the step (4) into a non-stick mold, steaming with steam, and forming;
(6) packaging, sterilizing and inspecting.
The poultry eggs are eggs.
Example 2: a dried poultry egg capable of preventing alcoholic liver injury is prepared from the following raw materials in parts by weight: 800 parts of whole egg liquid of poultry eggs, 20 parts of bruised ginger, 25 parts of flower of kudzuvine root, 5 parts of white paeony root, 4 parts of tsaoko amomum fruit, 9 parts of ginseng, 20 parts of tuckahoe, 30 parts of longan pulp, 10 parts of medlar, 12 parts of carapace and 30 parts of seasoning. The preparation method is the same as example 1. The poultry eggs are eggs.
Example 3: a dried poultry egg capable of preventing alcoholic liver injury is prepared from the following raw materials in parts by weight: 900 parts of whole egg liquid of poultry eggs, 40 parts of bruised ginger, 30 parts of flower of kudzuvine root, 7 parts of white paeony root, 5 parts of tsaoko amomum fruit, 5 parts of ginseng, 25 parts of tuckahoe, 30 parts of longan pulp, 5 parts of medlar, 15 parts of carapace and 40 parts of seasoning. The poultry eggs are duck eggs.
Example 4: acute and chronic toxicity test
Acute toxicity test of mice: the products of the examples 1 to 3 of the invention are adopted to completely replace the feed of mice to feed, the death and abnormal toxic reaction are not seen in the test period after continuous observation for 14 days, and the test mice are dissected and the liver, the kidney, the spleen, the stomach, the heart, the lung and the intestine are not abnormally changed after the test. The sample was of non-toxic grade according to the acute toxicity standard.
Chronic toxicity test: the products of the embodiments 1-3 of the invention are adopted to completely replace the feed of mice for feeding, and the results show that the feed is continuously fed for 90 days: the mice fed with the products of the invention examples 1-3 have smooth skin and hair, normal behavior and activity, normal drinking and eating, normal weight increase, fluctuation of blood biochemical index and hematology in normal range, fluctuation of urine routine and marrow index in normal range, no abnormality of tissue organs and no toxicological reaction on the whole.
As can be seen from the above experiments, the product of the invention is safe and nontoxic.
Examples5: animal testing
Taking 100 Kunming mice, each half of male and female, randomly dividing the mice into 5 groups, each group of male and female 10 mice, wherein the group 1 is a blank group, feeding the mice by adopting a common mouse feed, filling 56-degree red star Erguotou according to the dosage of 0.28 mL/(10 g for 1 day), and filling three times every day to achieve a moderate drunkenness state; groups 2-3 are experimental groups, and the products of the invention in the embodiments 1 and 2 are respectively fed to mice, and the 56-degree Hongxing Erguotou is drenched in a dose of 0.28mL/10g after being fed for two days, and the Hongxing Erguotou is drenched for three times every day, and the products of the invention are also fed in the experimental process; groups 4-5 are comparative test groups, and the products of comparative test examples 1 and 2 are respectively fed to mice, and after feeding for two days, the 56-degree Hongxing Erguotou is drenched with the dose of 0.28mL/10g for three times every day, and the products of comparative test examples 1 and 2 are also fed in the test process. After 5 days of continuous alcohol infusion, the drunk rate and the death rate are recorded, the surviving mice are killed after 5 days, the liver pathological changes are observed by microscopic examination, and the GSH-PX, MDA and TG levels in liver homogenate are measured, and the specific results are shown in the following table 1
TABLE 1 results of animal experiments
Group of |
Drunkenness rate |
Mortality rate |
MDA(nmol/mg) |
GSH-PX(U/L) |
TG(nmol/L) |
Microscopic examination result |
Group 1 |
70% |
35% |
5.67±1.42 |
34.19±8.17 |
1.74±0.41 |
Serious disease |
Group 2 |
20% |
0% |
3.49±1.97 |
24.79±6.97 |
0.54±0.11 |
No obvious liver injury pathological changes are seen |
Group 3 |
25% |
5% |
4.09±1.49 |
26.87±5.56 |
0.63±0.14 |
No obvious liver injury pathological changes are seen |
Group 4 |
50% |
20% |
4.97±1.89 |
29.97±7.99 |
1.22±0.25 |
Obvious liver injury pathological changes can be seen |
Group 5 |
55% |
25% |
5.01±1.78 |
31.45±9.76 |
1.34±0.32 |
Obvious liver injury pathological changes can be seen |
Normal mice |
/ |
/ |
3.25±1.67 |
23.71±8.09 |
0.49±0.19 |
Is normal |
Wherein,comparative test example 1Comprises the following steps: dried eggs are prepared from the following raw materials in parts by weight: 850 parts of whole egg liquid of eggs, 30 parts of bruised ginger, 25 parts of flower of kudzuvine root, 2 parts of white paeony root, 8 parts of tsaoko cardamon, 2 parts of ginseng, 5 parts of tuckahoe, 50 parts of longan pulp, 2 parts of medlar, 10 parts of carapace and 30 parts of seasoning. The preparation method is the same as that of example 1.
Comparative test example 2Comprises the following steps: a dried poultry egg capable of preventing alcoholic liver injury is prepared from the following raw materials in parts by weight: 850 parts of whole egg liquid of poultry eggs, 30 parts of bruised ginger, 28 parts of flower of kudzuvine root, 4 parts of tsaoko amomum fruit, 22 parts of poria cocos, 25 parts of longan pulp, 7 parts of medlar, 12 parts of carapace and 30 parts of seasoning. The preparation method is the same as that of example 1.
The results of the animal experiments show that the product can reduce the drunkenness rate and the death rate of mice, after the mice are drunk with white spirit for a long time, the levels of GSH-PX, MDA and TG in the liver of the mice are not greatly different from those of normal mice, and no obvious liver injury is found in microscopic examination. Compared with a comparative test example, the product of the invention has such good efficacy due to the unique formula composition and proportion, and unexpected technical effects are obtained, and the raw material composition and proportion ensure the realization of sobering up and protecting liver.
The construction of the animal model of the experiment refers to the article of Zhao Min et al, "the establishment and application of mouse acute alcoholic liver injury model" ("south China preventive medicine" volume 31, phase 1); 'animal model building method optimization of acute alcoholic liver injury of mouse' of Wanggangfang et al; and literature data such as "evaluation procedure and test method of health food functionality" (2003).
Example 6: sensory evaluation
Sensory flavor evaluations were performed on inventive examples 1, 2, and 3, comparative test examples 1 and 2 above, and comparative test examples 3 and 4 below, with a full score of 10 and a 6-point score of pass, and the results were evaluated by 10 sensory evaluators, respectively, as shown in table 2 below:
group of |
Example 1 |
Example 2 |
Example 3 |
Comparative example 1 |
Comparative example 2 |
Comparison 3 |
Comparative example 4 |
Scoring |
9.69 |
9.12 |
8.97 |
7.89 |
7.12 |
6.54 |
5.43 |
Wherein,comparative test example 3Comprises the following steps: dried eggs are prepared from the following raw materials in parts by weight: 850 parts of whole egg liquid of eggs, 30 parts of bruised ginger, 28 parts of flower of kudzuvine root, 8 parts of white paeony root, 8 parts of ginseng, 22 parts of tuckahoe, 25 parts of longan pulp, 7 parts of medlar, 12 parts of carapace and 30 parts of seasoning. The preparation method is the same as that of example 1.
Comparative test example 4Comprises the following steps: dried eggs are prepared from the following raw materials in parts by weight: 850 parts of whole egg liquid of eggs, 30 parts of bruised ginger, 28 parts of flower of kudzuvine root, 8 parts of white paeony root, 4 parts of tsaoko amomum fruit, 8 parts of ginseng, 22 parts of tuckahoe, 7 parts of medlar, 12 parts of carapace and 30 parts of seasoning. The preparation method is the same as that of example 1.
From the test results, the unique raw material composition and proportion of the invention also guarantee good flavor.
Example 7: clinical trial
Clinical data: the invention takes the alcoholic liver disease of traditional Chinese medicine as an example, and 30 cases of clinical observation show. The traditional Chinese medicine alcoholic liver is selected as a standard, a patient has long-term and large-scale drinking history, and 42-degree white spirit is more than 2 years per day for more than 2 years; inappetence, fatigue, weakness, emaciation; mild or moderate hepatic fibrosis; serum glutamic-oxaloacetic transaminase is remarkably increased, and glutamic-pyruvic transaminase is normal, and the ratio of the two is 2: 1-6: 1. The diagnosis can be confirmed by the above symptoms. The subjects observed by diagnosis were all male and had no other serious diseases. The age is 35-42 years.
And (3) judging the curative effect:
the effect is shown: the symptoms disappear, the appetite is good, the fatigue is weak, and the body is strong; the weight loss is improved, and the body is comfortable; the hepatic fibrosis examination 4 indexes are all qualified; the glutamic-oxaloacetic transaminase is reduced obviously, and the ratio of the glutamic-oxaloacetic transaminase to the glutamic-pyruvic transaminase is less than 2: 1.
The method has the following advantages: inappetence, fatigue, weakness and emaciation are relieved; the glutamic-oxalacetic transaminase is reduced by more than 10 percent.
And (4) invalidation: no change in symptoms.
In clinical trials, other medicines and nutritional health products are stopped taking, the dried poultry egg capable of preventing alcoholic liver injury, which is prepared by the embodiment 1 of the invention, is taken, and 1 period is observed for 2 months. The taking method comprises the following steps: the daily dosage of 80g is taken as dish or snack, the symptom is relieved after 1 month, and the symptom is obviously relieved after 2 months of taking. Of 30 patients in clinical experiments, 17 patients have significant effect, 10 patients have effect, 3 patients have no effect, and the total effective rate is 90%.
In conclusion, the product has good effects of relieving alcoholism and protecting liver, has a certain curative effect on alcoholic liver injury which occurs already, and has the effect of relieving symptoms of the alcoholic liver injury, in addition, the product can be eaten as snacks or dishes, the trouble that the existing antialcoholic drugs must be eaten before or after meals is effectively solved, and the product has good flavor and is popular with consumers due to the specific proportion and formula, so that people can avoid liver injury caused by drinking while enjoying delicious food, and the product has wide market prospect.
The inventors deliberately suggest that: excessive drinking is harmful to health and does not require excessive drinking!
The raw materials of the invention can be purchased from the market. The above disclosure is only for the specific embodiment of the present invention, but the present invention is not limited thereto, and any variations that can be made by those skilled in the art should fall within the scope of the present invention.