CN103405695A - 一种治疗小儿湿疹的中药组合物 - Google Patents
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Abstract
一种治疗小儿湿疹的中药组合物，该中药组合物由土茯苓、生地、白术、贯众、苍术、赤芍、金银花、蒲公英、芦荟、当归制成。临床可用于治疗小儿湿疹。
Description
一种治疗小儿湿疹的中药组合物
技术领域
[0001] 本发明属于中药技术领域，尤其是涉及一种治疗小儿湿疹的中药组合物。
背景技术
[0002] 小儿湿疹是一种变态反应性皮肤病，即平常说的过敏性皮肤病。主要原因是对食入物、吸入物或接触物不耐受或过敏所致。患有湿疹的孩子起初皮肤发红、出现皮疹、继之皮肤发糙、脱屑，抚摩孩子的皮肤如同触摸在砂纸上一样。遇热、遇湿都可使湿疹表现显著。西医治疗尚无特效疗法，并存在副作用大，易继发感染，远期疗效不理想等缺点。本发明人经过多年实践，发现中医治疗小儿湿疹具有良好疗效。
发明内容
[0003] 本发明的目的在于提供一种治疗效果好、有效率高、对人体无毒副作用的治疗小儿湿疹的中药组合物。
[0004] 本发明的目的是这样实现的，根据中医药理论，利用中药独特的药性，采用土茯苓、生地、白术、贯众、苍术、赤芍、金银花、蒲公英、芦荟、当归按照一定的配伍要求，经过加工制成。
[0005] 制备本发明中药组合物由下述原料药制成:土获茶10-15份、生地10-15份、白术8-12份、贯众8-12份、苍术8-12份、赤芍8_12份、金银花8_12份、蒲公英8_12份、芦荟5-10份、当归5-10份。
[0006] 本发明中药组合物原料药的最佳重量份为:土茯苓12份、生地12份、白术10份、贯众10份、苍术10份、赤芍10份 、金银花10份、蒲公英10份、芦荟8份、当归8份。
[0007] 本发明中药的药理作用如下:
[0008] 土茯苓:甘淡，平。归肝经；胃经；脾经。解毒，除湿，利关节。主治梅毒，淋浊，筋骨挛痛，脚气，疗疔疮，痈肿，瘰疬，梅毒及汞中毒所致的肢体拘挛，筋骨疼痛。
[0009] 生地:味甘、苦，微寒。归心、肝、肾经。主治滋阴清热；凉血补血。主热病烦渴；内热消渴；骨蒸劳热；温病发斑；血热所致的吐血；崩漏；尿血；便血；血虚萎黄；眩晕心悸；血少经闭。
[0010] 白术:苦、甘、温。归脾、胃经。补气健脾，燥湿利水，止汗，安胎。用于脾胃气虚，运化无力，食少便溏，脘腹胀满，脾虚水停，而为痰饮、水肿、小便不利，胎动不安等。
[0011] 贯众:苦，微寒。有小毒。归肝、脾经。清热解毒，凉血止血，杀虫。有凉血止血之功，主治血热所致之衄血、吐血、便血、崩漏等症，尤善治崩漏下血。
[0012] 苍术:辛、苦、温，归脾、胃经。燥湿健脾，祛风湿。用于湿滞中焦证，风湿痹证，外感风寒挟湿之表证。
[0013] 赤芍:苦、微寒。归肝、脾经。清热凉血，活血祛瘀。用于温毒发斑，肠风下血，痈肿疮瘍等。
[0014] 金银花:甘、寒，归肺、心、胃经。清热解毒，疏散风热。用于痈肿疔疮、热毒血痢。[0015] 蒲公英:甘、寒，归肝、胃经。清热解毒，消痈散结。用于痈肿疔疮、热淋涩痛。
[0016] 芦荟:苦、寒。归肝、大肠经。泻下，清肝，杀虫。用于热结便秘；肝火头痛，目赤惊风，虫积腹痛，疥癣，痔瘘，解巴豆毒。
[0017] 当归:甘、辛、温，归肝、心、脾经。补血，活血，调经，止痛。用于心肝血虚、痈疽疮疡。
[0018] 本发明中药组合物于2005年至2012年临床观察小儿湿疹110例患者，临床报告如下:
[0019] 1、一般资料
[0020] 110例患者中，年龄2个月-5岁，病程多在3个月到2年，平均年龄1.5岁。
[0021] 2、诊断标准
[0022] 参照《临床皮肤病学》中的小儿湿疹的诊断标准:
[0023] (I)出生后1-2个月发病，多见于肥胖或营养不良的婴儿；
[0024] (2)颜面、头皮、耳部为好发部位，一般不累及口周和鼻尖部；
[0025] (3)损害为多形性，有红斑、丘疹、水疱、糜烂、渗液及结痂；
[0026] (4)瘙痒，患儿烦躁不安；
[0027] (5)病程较长，反复发作，多在断奶后减轻。
[0028] 3、治疗方法
[0029] 3.1处方:土茯苓12g，生地12g，白术10g，贯众10g，苍术10g、赤芍10g，金银花10g、蒲公英10g、芦荟8g、当归8g。
[0030] 3.2制备及使用方法:上述药物按常规工艺制成汤剂，口服每日I剂，每日2次，7天为一个疗程。
[0031] 4、治疗结果:
[0032] 4.1治疗评定标准，根据国家中医药管理局制定的《中医病证诊断疗效标准》判定:
[0033] 治愈:瘙痒消失，皮损消退彡90% ；
[0034] 显效:瘙痒症状明显减轻，皮损消退彡70% ；
[0035] 有效:瘙痒症状有所减轻，皮损消退> 30% ；
[0036] 无效:瘙痒症状无变化，皮损消退〈30%。
[0037] 4.2结果:110例患者中，治愈72例(65.4% )，显效18例(16.4%)，有效12例(10.9% ),无效8例(7.3%)，总有效率为92.7%。
[0038] 5、典型病例
[0039] 5.1黄某，男，9个月。出生3月后头面部出现红色皮疹，瘙痒甚，后患部破溃流水，形成黄色结痂，愈后复出，舌红苔黄。服用本发明药物，治疗2个疗程，服后没有新的皮疹出现，破溃减少，结痂明显脱落，瘙痒减轻，继续服用3个疗程，痊愈，半年后随访无复发。
[0040] 5.2孟某，女，2岁5个月。周身遍布红色粟粒样皮疹，四肢皮疹渗出，轻度糜烂，局部皮肤增厚，呈轻度苔藓样变，伴有抓痕和血痂。服用本发明药物，每日I剂，2个疗程后，渗液即吸收，后皮疹退，肤色逐渐恢复正常渗液即吸收，后皮疹退，肤色逐渐恢复正常，其余症状减轻。继续服用3个疗程，痊愈，一年后随访无复发。具体实施方式
[0041] 下面结合实施例对本发明作进一步的说明，下述该实施例仅用于说明本发明而对本发明没有限制。
[0042] 实施例1，一种治疗小儿湿疹的中药组合物，是由土茯苓10g、生地10g、白术8g、贯众8g、苍术8g、赤芍8g、金银花8g、蒲公英8g、芦荟5g、当归5g制成。
[0043] 实施例2，一种治疗小儿湿疹的中药组合物，是由土茯苓12g、生地12g、白术10g、贯众log、苍术10g、赤芍10g、金银花10g、蒲公英10g、芦荟8g、当归8g制成。
[0044] 实施例3，一种治疗小儿湿疹的中药组合物，是由土茯苓15g、生地15g、白术12g、贯众12g、苍术12g、赤芍12g、金银花12g、蒲公英12g、芦荟10g、当归IOg制成。
Claims (2)
1.一种治疗小儿湿疹的中药组合物，其特征在于包括下述原料药: 土茯苓10-15份、生地10-15份、白术8-12份、贯众8-12份、苍术8-12份、赤芍8-12份、金银花8-12份、蒲公英8-12份、芦荟5-10份、当归5_10份。
2.根据权利要求1所述的中药组合物，其特征在于包括下述原料药: 土茯苓12份、生地12份、白术10份、贯众10份、苍术10份、赤芍10份、金银花10份、蒲公英10份、芦荟8份、当归8份。`
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