CN103394009A - Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method - Google Patents
Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method Download PDFInfo
- Publication number
- CN103394009A CN103394009A CN2013103184515A CN201310318451A CN103394009A CN 103394009 A CN103394009 A CN 103394009A CN 2013103184515 A CN2013103184515 A CN 2013103184515A CN 201310318451 A CN201310318451 A CN 201310318451A CN 103394009 A CN103394009 A CN 103394009A
- Authority
- CN
- China
- Prior art keywords
- rhizoma
- chinese medicine
- wound
- treatment
- ulcer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 208000014674 injury Diseases 0.000 title abstract description 13
- 206010040943 Skin Ulcer Diseases 0.000 title abstract description 6
- 206010012601 diabetes mellitus Diseases 0.000 title abstract description 4
- 230000008733 trauma Effects 0.000 title abstract description 3
- 208000003790 Foot Ulcer Diseases 0.000 title abstract 3
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 52
- 239000000843 powder Substances 0.000 claims abstract description 48
- 206010052428 Wound Diseases 0.000 claims abstract description 46
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 230000001954 sterilising effect Effects 0.000 claims abstract description 4
- 208000025865 Ulcer Diseases 0.000 claims description 30
- 231100000397 ulcer Toxicity 0.000 claims description 30
- 239000002674 ointment Substances 0.000 claims description 26
- 235000011837 pasties Nutrition 0.000 claims description 26
- 241000282894 Sus scrofa domesticus Species 0.000 claims description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 11
- 210000002700 urine Anatomy 0.000 claims description 11
- 208000014770 Foot disease Diseases 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000008157 edible vegetable oil Substances 0.000 claims description 5
- 239000003921 oil Substances 0.000 claims description 2
- 239000008280 blood Substances 0.000 abstract description 21
- 210000004369 blood Anatomy 0.000 abstract description 20
- 230000001737 promoting effect Effects 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 15
- 208000002193 Pain Diseases 0.000 abstract description 14
- 230000036407 pain Effects 0.000 abstract description 13
- 230000004087 circulation Effects 0.000 abstract description 9
- 238000002156 mixing Methods 0.000 abstract description 7
- 230000029663 wound healing Effects 0.000 abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 206010061218 Inflammation Diseases 0.000 abstract description 5
- 201000010099 disease Diseases 0.000 abstract description 4
- 230000006870 function Effects 0.000 abstract description 3
- 239000000463 material Substances 0.000 abstract description 3
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 231100000241 scar Toxicity 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000032544 Cicatrix Diseases 0.000 abstract 1
- 241001071917 Lithospermum Species 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 230000006978 adaptation Effects 0.000 abstract 1
- 230000000740 bleeding effect Effects 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 230000037387 scars Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 10
- 230000035876 healing Effects 0.000 description 10
- 206010040872 skin infection Diseases 0.000 description 10
- 206010007247 Carbuncle Diseases 0.000 description 8
- 208000008960 Diabetic foot Diseases 0.000 description 8
- 206010062717 Increased upper airway secretion Diseases 0.000 description 8
- 230000023597 hemostasis Effects 0.000 description 8
- 208000026435 phlegm Diseases 0.000 description 8
- 206010017553 Furuncle Diseases 0.000 description 7
- 210000000589 cicatrix Anatomy 0.000 description 7
- 210000000265 leukocyte Anatomy 0.000 description 7
- 210000003141 lower extremity Anatomy 0.000 description 7
- 208000009084 Cold Injury Diseases 0.000 description 6
- 206010010904 Convulsion Diseases 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 6
- 230000002595 cold damage Effects 0.000 description 6
- 230000036461 convulsion Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 6
- 231100000614 poison Toxicity 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 208000032843 Hemorrhage Diseases 0.000 description 5
- 230000036592 analgesia Effects 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 206010037844 rash Diseases 0.000 description 5
- 230000008961 swelling Effects 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 230000017423 tissue regeneration Effects 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 206010060891 General symptom Diseases 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 208000006877 Insect Bites and Stings Diseases 0.000 description 4
- 241000395033 Kaempferia Species 0.000 description 4
- 235000013422 Kaempferia rotunda Nutrition 0.000 description 4
- 230000001741 anti-phlogistic effect Effects 0.000 description 4
- 230000003750 conditioning effect Effects 0.000 description 4
- 201000005884 exanthem Diseases 0.000 description 4
- 210000003714 granulocyte Anatomy 0.000 description 4
- 230000003448 neutrophilic effect Effects 0.000 description 4
- 230000008736 traumatic injury Effects 0.000 description 4
- 241000721047 Danaus plexippus Species 0.000 description 3
- 208000010201 Exanthema Diseases 0.000 description 3
- 206010053615 Thermal burn Diseases 0.000 description 3
- 239000002260 anti-inflammatory agent Substances 0.000 description 3
- 230000002218 hypoglycaemic effect Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 231100000019 skin ulcer Toxicity 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 208000011580 syndromic disease Diseases 0.000 description 3
- 241000282472 Canis lupus familiaris Species 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 241000282326 Felis catus Species 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 201000005505 Measles Diseases 0.000 description 2
- 241000131808 Scolopendra Species 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 2
- 206010000269 abscess Diseases 0.000 description 2
- 238000002266 amputation Methods 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 238000001804 debridement Methods 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 235000021323 fish oil Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 238000009169 immunotherapy Methods 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 201000007227 lymph node tuberculosis Diseases 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 208000035824 paresthesia Diseases 0.000 description 2
- 201000003068 rheumatic fever Diseases 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000003014 Bites and Stings Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 206010017062 Formication Diseases 0.000 description 1
- 206010017711 Gangrene Diseases 0.000 description 1
- 208000005577 Gastroenteritis Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000032912 Local swelling Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 241000489991 Melanthiaceae Species 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 241000283898 Ovis Species 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 240000005373 Panax quinquefolius Species 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 241000219000 Populus Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 206010046996 Varicose vein Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 208000012873 acute gastroenteritis Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003255 anti-acne Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000003445 biliary tract Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- -1 clean Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002641 glycemic effect Effects 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 230000002008 hemorrhagic effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 210000004935 right thumb Anatomy 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 208000027185 varicose disease Diseases 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a traditional Chinese medicine for treating trauma and diabetes foot ulcer and a preparation method. The medicine comprises the following raw materials in parts by mass: 1-2.5 parts of rhizoma paridis, 0.8-1.5 parts of rhizoma paridis, 0.5-1 part of rhizoma arisaematis, 0.5-2 parts of rhizoma kaempferiae, and 0.5-1 part of lithospermum. The preparation method comprises the following steps of mixing the raw materials and then grinding to 100-180 meshes, and sterilizing to obtain powder. The medicine has the functions of promoting and adjusting the circulation of qi and blood of the meridian, fighting against bacterium and diminishing inflammation, stopping bleeding and dissipating blood stasis, promoting qi and relieving pain, and clearing away heat and toxic materials, is dramatic in the effect of regenerating tissue to heal wound, rapid in wound healing, and wide in adaptation diseases, and is especially applicable to the treatment of diabetes foot ulcer, with little acne signs or scars left.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of wound and bran urine foot disease ulcer, also relate to the preparation method of this medicine, belong to the Chinese medicine technical field.
Background technology
China Patent Publication No.: CN102688368A; Open day: on 09 26th, 2012; Denomination of invention " a kind of Chinese medicine for the treatment of trauma hemostasis and intractable ulcer ", by the ingredients of following weight portion: Scolopendra 50-55 part, Cortex Moutan charcoal 30-35 part, Rhizoma Paridis 3-5 part, Radix Notoginseng 3-5 part, Herba Cirsii 3-5 part, Gypsum Fibrosum Preparatum 3-5 part.Further clear and definite Scolopendra in drug matching, joining " monarch drug " and the status of Cortex Moutan charcoal " ministerial drug " in main, the formulation principle that meets monarch, have that hemostasis, detumescence relieve the pain, the effect of blood stasis dispelling, hard masses softening and resolving, be used for the treatment of intractable ulcer, large-area burns and hemostasis.This technical scheme is relatively paid attention to the detumescence of ulcer wound surface is relieved the pain, and hard masses softening and resolving and removing pyretic toxicity, but ignored the promoting the circulation of QI to relieve pain of whole body of human body meridians and the endogenous wind stopping relieving convulsion on meridians, and expelling wind for relieving convulsion is poor to the conditioning effect of Whole Body; At removing heat from blood, invigorate blood circulation, anti-inflammation, detoxifcation rash and the metabolism that accelerates pox seal and cicatrix, promoting tissue regeneration and ulcer healing, make the rear preventing from scar of wound surface, and the cosmetology aspect, particularly to also perfect not to the utmost on the immunotherapy targeted autoantibody of diabetic foot ulcer.
Summary of the invention
the objective of the invention is to pay attention to for prior art the reparation of local lesion, and the QI and blood of ignoring human body is nursed one's health and defect and the deficiency of strengthening body resistance and dispelling evil, a kind of Chinese medicine and preparation method for the treatment of wound and bran urine foot disease ulcer proposed, described Chinese medicine can promote QI-blood circulation and the conditioning of collaterals of human, anti-inflammation, the hemostasis dissipating blood stasis, the circulation of qi promoting analgesia, heat-clearing and toxic substances removing, the promoting tissue regeneration and ulcer healing successful, wound healing is fast, pox seal and cicatrix are few, indication is extensive, be particularly suitable for the immunotherapy targeted autoantibody to diabetic foot ulcer, described method is simple, easy to operate, production cost is lower.
The object of the present invention is achieved like this, a kind of Chinese medicine for the treatment of wound and bran urine foot disease ulcer, and the raw material of described Chinese medicine forms and the mass parts ratio is: RHIZOMA BISTORTAE 1~2.5; Rhizoma Paridis 0.8~1.5; Rhizoma Arisaematis (processed) 0.5~1; Rhizoma Kaempferiae 0.5~2; Radix Arnebiae (Radix Lithospermi) 0.5~1.
The raw material of described Chinese medicine forms and the mass parts ratio is: RHIZOMA BISTORTAE 2; Rhizoma Paridis 1; Rhizoma Arisaematis (processed) 1; Rhizoma Kaempferiae 2; Radix Arnebiae (Radix Lithospermi) 0.5.
The preparation method of Chinese medicine of the present invention is to take RHIZOMA BISTORTAE in the mass parts ratio, Rhizoma Paridis, and Rhizoma Arisaematis (processed), Rhizoma Kaempferiae and Radix Arnebiae (Radix Lithospermi), be crushed to 100~180 orders after it is mixed, and be sterilizing, obtains powder.
By described powder water or edible oil furnishing pasty state, obtain unguentum,
Described water is normal saline, and the mass ratio of described powder and normal saline is 40:60~60:40.
Described oil is Oleum sesami or Adeps Sus domestica, and the mass ratio of described powder and Oleum sesami is 45:55~55:45, and the mass ratio of described powder and Adeps Sus domestica is 35:65~55:45.
In Chinese medicine of the present invention
RHIZOMA BISTORTAE has another name called Rhizoma Paridis.Bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing.The diseases such as treatment of ulcer carbuncle furuncle, hygropyretic dysentery.Hemostasis and antibacterial action are arranged.
Rhizoma Paridis is that Liliales Trilliaceae plant has another name called Rhizoma Paridis, is the rhizome of Rhizoma Paridis, is heat and toxic materials clearing away medicine, and hardship, be slightly cold.Slightly poisonous, GUIXIN, lung, Liver Channel.Have the effects such as heat-clearing and toxic substances removing, reducing swelling and alleviating pain, hemostasis, the treatment traumatic injury has unique curative effect.For the high heat of epidemic febrile disease, convulsion with spasms, or excessive noxious heat, laryngopharynx swelling and pain.Also can be used for hot carbuncle toxin, scrofula, venom.Discovered in recent years Rhizoma Paridis and chemical composition thereof have good antibacterial action, antiinflammatory action, anti-ulcer effect, antitumor action, Cardiovascular, sedation and analgesia effect, function of relieving cough and calming asthma and but the physiologically actives such as essence effect.
Rhizoma Arisaematis (processed), have another name called Rhizoma Arisaematis, Jiang Nan magnitude.This product pungent drugs can disperse and bitter drugs can purge, warm-dryness syndrome reduces phlegm, and both except the meridians wind-phlegm, except the taste damp-phlegm, is longer than the endogenous wind stopping relieving convulsion again, is suitable for all cards of wind-phlegm and pertinacious phlegm cough with asthma, is the strong product of warm-dryness syndrome.Has drying dampness to eliminate phlegm, expelling wind for relieving convulsion, the effect of dispersing swelling and dissipating binds.Cure mainly middle wind-phlegm and stop up, deviation of the eye and mouth, hemiplegia, epilepsy, infantile convulsion, tetanus, dizziness due to wind-phlegm, sore throat, scrofula, the carbuncle furuncle, fall and flutter folding wound, snake bite and insect sting.
Rhizoma Kaempferiae is again Rhizoma Kaempferiae, nature and flavor: suffering, temperature.Return the stomach warp.Warming middle-JIAO for eliminating dampness, promoting the circulation of QI to relieve pain.Have the circulation of qi promoting warming middle-JIAO, help digestion, the effect of pain relieving.Cure mainly acute gastroenteritis, dyspepsia, the septum pectorale distension, coldness and pain in the epigastrium, diet does not disappear.Cold syndrome of the stomach pain, toothache, rheumatic arthritis, traumatic injury.Radix Arnebiae (Radix Lithospermi) claim again Zi Dan, purple Yao, blood etc., cure mainly: removing heat from blood, invigorate blood circulation, the detoxifcation rash.For heat in blood poison contain, purple black, the measles without adequate eruption of macule, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood, for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.
Because the Radix Arnebiae (Radix Lithospermi) major function is removing heat from blood, blood circulation promoting and blood stasis dispelling, the detoxifcation rash, therefore can accelerate the metabolism of pox seal and cicatrix, add the bactericidal antiphlogistic effect that it is good, Radix Arnebiae (Radix Lithospermi) has the effect of significant anti-acne and antiinflammatory, and very large its cosmetic values is arranged, and the lithosperman in Radix Arnebiae (Radix Lithospermi) also has hypoglycemic effect simultaneously.Chinese medicine of the present invention is take RHIZOMA BISTORTAE as monarch drug, Rhizoma Paridis, Radix Arnebiae (Radix Lithospermi) are ministerial drug, take Rhizoma Arisaematis (processed) as corrigent, with Rhizoma Kaempferiae for making medicine, all medicine synergism, make Chinese medicine of the present invention can be acted on by wound surface the meridian qi and blood operation of patient's human body, thereby trace back this by mark, reach this positive source clearly, the effect for the treatment of both the principal and secondary aspects of a disease, to various wounds such as bullet, Jin Ren, traumatic injury, injury by overexertion, burn and scald, cold injury and insect-animal injury all have the curative effect of anti-inflammation, hemostasis dissipating blood stasis, circulation of qi promoting analgesia, heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing and cosmetology preferably.
particularly the present invention is directed to the diabetics immunologic function degression, resistance reduces, easily infect and occur that the skin scabies is swollen, breathe, the various inflammation such as urinary system biliary system, and the sensory nerve obstacle causes extremity tip position paresthesia of skin, as formication, numb, prickling sensation, the symptoms such as pruritus, in conjunction with its cause of disease master at lung, stomach, kidney, basic pathogenesis is cloudy body fluid deficiency consumption, the principle of scorching inclined to one side Sheng, by acting on the heart, lung, the RHIZOMA BISTORTAE of Liver Channel, Rhizoma Paridis, the Radix Arnebiae (Radix Lithospermi) collateral dredging is invigorated blood circulation, reduce blood glucose, bactericidal antiphlogistic, removing pathogenic heat from blood and toxic substance from the body, improve patient's self resistance and immunocompetence, improve the microcirculation situation of ulcer spot, by Rhizoma Kaempferiae and the Rhizoma Arisaematis (processed) circulation of qi promoting analgesia that acts on the stomach warp, the hemostasis dissipating blood stasis, promoting tissue regeneration and ulcer healing, accelerate reparation and the healing of ulcer spot, the diabetic foot ulcer disease is had to therapeutic effect preferably.
Beneficial effect of the present invention:
1. medicine material compatibility of the present invention is reasonable, and composition is simple, and indication is in extensive range, to the various outer hemorrhagic wounds that injure, as to insect-animal injury, skin infection, carbuncle furuncle, burn, the cold injury therapeutic effect is obvious, wound healing is fast, and wound healing is effective, reduces softening cicatrix, the beautifying skin effect.
2. medicine of the present invention is based on the conditioning of Whole Body, bactericidal antiphlogistic, blood circulation promoting and blood stasis dispelling, dispelling toxicity, detoxicating, circulation of qi promoting analgesic effect is obvious, and is better to the conditioning effect of Whole Body, be conducive to improve the resistance of human body self, immunity and anti-tumor capacity, and accelerate the healing of wound surface.
3. medicine of the present invention can improve the microcirculation situation of ulcer spot, bactericidal antiphlogistic, the promoting tissue regeneration and ulcer healing successful, particularly the Radix Arnebiae (Radix Lithospermi) in medicine of the present invention has certain hypoglycemic activity, can accelerate reparation and the healing of ulcer spot, the diabetic foot ulcer disease is had to therapeutic effect preferably.
4. the present invention can reduce wound exudate, and convergence, analgesia, have therapeutic effect preferably to the rheumatic arthritis arthralgia.
Chinese medicine of the present invention is treated totally 305 examples through Hospital Attached to Hubei Chinese Medicine College's clinical experiment.Wherein relate to cutter, rifle is hemorrhage and traumatic injury 58 examples, burn 66 examples (burn example, scald example), cold injury 41 examples, insect-animal injury 30 examples (redness that unknown insect bite causes and skin infection 12 examples, pet cat, Canis familiaris L. sting, scratch 18 examples), skin infection, carbuncle furuncle 61 examples, diabetic foot ulcer 49 examples, its therapeutic effect refers to table one.
Various wounds in table one, the curative effect determinate standard of skin infection, carbuncle furuncle and diabetic foot ulcer is:
1. recovery from illness: General Symptoms disappears, and local swelling is dissipated, or pus absorption dissipation, or skin ulcer face healing after bursting, and blood leukocytes is normally total.
2. produce effects: General Symptoms disappears, and swelling, abscess or the open sore part have been dwindled more than 70%, and the blood leukocytes sum is normal.
3. effective: General Symptoms alleviates, and swelling, abscess or the open sore part have been dwindled more than 30%, and below 70%, the blood leukocytes sum approaches normal.
4. invalid: as not reach effective standard.
Table one
Annotate: in table one, 32 exceptions are hindered hemorrhage, 28 routine burns (burn 4 examples, scald 14 examples), 37 routine cold injury, 23 routine insect-animal injurys (redness that unknown insect bite causes and skin infection 15 examples, pet cat, Canis familiaris L. 8 examples of stinging, scratch), 27 routine skin infection, carbuncle furuncle, 14 routine diabetic foot ulcer patients' wound surface more after without cicatrix.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
Embodiment 1:
By 1 kilogram of dry product raw material RHIZOMA BISTORTAE; 0.8 kilogram of Rhizoma Paridis; 0.5 kilogram of Rhizoma Arisaematis (processed); After 0.5 kilogram of Rhizoma Kaempferiae and 0.5 kilogram of mixing of Radix Arnebiae (Radix Lithospermi), be crushed to 100 orders, drying and sterilizing at 80 ℃ of temperature, obtain powder of the present invention.
Also can by described powder and normal saline in mass ratio routine 40:60 be modulated into the pasty state unguentum.Also can by described powder and Oleum sesami in mass ratio routine 45:55 be modulated into the pasty state unguentum, or by described powder and Adeps Sus domestica in mass ratio routine 35:65 be modulated into the pasty state unguentum.By its powder water or edible oil furnishing pasty state, obtain unguentum.
Powder available water of the present invention or edible oil furnishing pasty state, obtain unguentum.Described water is distilled water or pure water, preferably medical saline.Described edible oil is Oleum Arachidis hypogaeae semen, Oleum Brassicae campestris, olive oil, fish oil, Adeps Bovis seu Bubali, Adeps Caprae seu ovis etc., but preferably Oleum sesami and Adeps Sus domestica.While with Adeps Sus domestica and powder, being in harmonious proportion, can first Adeps Sus domestica be dissolved, then with powder furnishing pasty state, after Adeps Sus domestica is cooling harder cream piece, during use, the cream piece is cut into to lamellar and spreads on affected part and get final product, or gauze is wrapped up again.
Embodiment 2:
By 2 kilograms of dry product raw material RHIZOMA BISTORTAEs; 1 kilogram of Rhizoma Paridis; 1 kilogram of Rhizoma Arisaematis (processed); After 1 kilogram of Rhizoma Kaempferiae and 0.5 kilogram of mixing of Radix Arnebiae (Radix Lithospermi), be crushed to 150 orders, adopt 90 ℃ of high temperature sterilizes, obtain Chinese powder medicine of the present invention.Also can by described powder and normal saline in mass ratio routine 60:40 be modulated into the pasty state unguentum, also can by described powder and Oleum sesami in mass ratio routine 55:45 be modulated into the pasty state unguentum, or by described powder and Adeps Sus domestica in mass ratio routine 65:35 be modulated into the pasty state unguentum.
Embodiment 3:
By 2.5 kilograms of dry product raw material RHIZOMA BISTORTAEs; 1.5 kilograms of Rhizoma Paridis; 1 kilogram of Rhizoma Arisaematis (processed); 1 kilogram of 2 kilograms of Rhizoma Kaempferiaes and Radix Arnebiae (Radix Lithospermi).After mixing, be crushed to 180 orders, adopt ultraviolet disinfection, obtain Chinese powder medicine of the present invention.Also can by described powder and normal saline in mass ratio routine 50:50 be modulated into the pasty state unguentum, also can by described powder and Oleum sesami in mass ratio routine 50:50 be modulated into the pasty state unguentum.Also can described powder and Adeps Sus domestica in mass ratio routine 65:35 be modulated into the pasty state unguentum, or by described powder and Adeps Sus domestica in mass ratio routine 50:50 be modulated into the pasty state unguentum.
Embodiment 4:
By 1.5 kilograms of raw material RHIZOMA BISTORTAEs; 0.9 kilogram of Rhizoma Paridis; 0.9 kilogram of Rhizoma Arisaematis (processed); After 1.5 kilograms of Rhizoma Kaempferiaes and 0.8 kilogram of mixing of Radix Arnebiae (Radix Lithospermi), be crushed to 160 orders, adopt ultraviolet disinfection, obtain Chinese powder medicine of the present invention.Also can by described powder and normal saline in mass ratio routine 58:42 be modulated into the pasty state unguentum, also can by described powder and Oleum Arachidis hypogaeae semen in mass ratio routine 54:46 be modulated into the pasty state unguentum, or by described powder and Adeps Sus domestica in mass ratio routine 45:55 be modulated into the pasty state unguentum.
Embodiment 5:
By 1 kilogram of raw material RHIZOMA BISTORTAE; 1.2 kilograms of Rhizoma Paridis; 0.8 kilogram of Rhizoma Arisaematis (processed); After 1.5 kilograms of Rhizoma Kaempferiaes and 0.8 kilogram of mixing of Radix Arnebiae (Radix Lithospermi), be crushed to 140 orders, adopt microwave sterilizating, obtain Chinese powder medicine of the present invention.Also can by described powder and distilled water in mass ratio routine 58:42 be modulated into the pasty state unguentum, also can by described powder and Oleum sesami in mass ratio routine 54:46 be modulated into the pasty state unguentum, or by described powder and fish oil in mass ratio routine 55:45 be modulated into the pasty state unguentum.
Embodiment 6:
By 1.2 kilograms of dry product raw material RHIZOMA BISTORTAEs; 0.9 kilogram of Rhizoma Paridis; 0.6 kilogram of Rhizoma Arisaematis (processed); After 1.8 kilograms of Rhizoma Kaempferiaes and 0.6 kilogram of mixing of Radix Arnebiae (Radix Lithospermi), be crushed to 120 orders, adopt microwave sterilizating, obtain Chinese powder medicine of the present invention.Also can by described powder and 0.5% normal saline in mass ratio routine 43:57 be modulated into the pasty state unguentum, also can by described powder and Oleum sesami in mass ratio routine 58:42 be modulated into the pasty state unguentum, or by described powder and Adeps Sus domestica in mass ratio routine 60:40 be modulated into the pasty state unguentum.
Described powder and unguentum can directly spread, are coated with or spread on affected part and get final product, or, again with the gauze wrapping, change dressings one to twice in 1st.For hemorrhage wound and insect-animal injury, a course for the treatment of, can fully recover.General minor cut or wound seven days was a course for the treatment of, and large wound fortnight is a course for the treatment of.For scalding, burn and cold injury, skin infection, carbuncle furuncle, can fully recover one or two course for the treatment of.General little wound surface seven days was a course for the treatment of, and large wound surface seven days was a course for the treatment of.
For the diabetic foot ulcer treatment cycle, be about two courses for the treatment of, fortnight is a course for the treatment of.
Concrete case
The week * *, female, 74 years old, skin infection, intractable ulcer patient, two more than ten years of two varicose veins of the lower extremity, left lower extremity ulcer 6 wheat harvesting periods, part presents swollen, hard tuberosity, increases gradually, has risen the root bundle, the skin ulcer color is red, and there are purulent core, a plurality of pus heads in the skin ulcer top, pain is obvious, tenderness, blood leukocytes sum and neutrophilic granulocyte number increase, blood leukocytes sum 1.5 ╳ 10
9/ l, neutrophilic granulocyte is several 75%, seeks medical advice everywhere, and treatment substantially to no effect, has hospital's suggestion amputation.Rear employing treatment by Chinese herbs of the present invention, spread powder of the present invention to ulcer surface after cleaning once a day wound surface, then with the gauze wrapping, medication is after 7 days, and redness obviously alleviates, and ulcer surface dwindles, and the blood leukocytes sum is down to 0.9 ╳ 10
9/ l, neutrophilic granulocyte is several 62%, continues medication to the 14 days, and left lower extremity is without red, swollen, without pain, the ulcer wound surface healing, the blood leukocytes sum is down to 0.7 ╳ 10
9/ l, neutrophilic granulocyte is several 50%, does not stay obvious cicatrix, the treatment recovery from illness.
Liu * *, the female, 31 years old, right thumb cutter incised wound, long 4 centimetres of wound, dark 0.5 centimetre, frequently-occurring hemorrhage, through the wound surface hydrogen peroxide, clean, powder of the present invention is spread to wound surface, pressure dressing, wound surface is hemorrhage namely to be stopped, changing dressings once in 1st, wound healing after 7 days.
Grandson * *, the man, 70 years old, diabetic history 20 years, sky takes blood glucose 14mnol/l, urine examination ++, left lower extremity ulcer gangrene 3 years, numb around ulcer, feel to go down, hospital's suggestion amputation is arranged, the oral administration hypoglycemic medicine, glycemic control is in the 6.5mnol/l left and right, rear employing Chinese medicine of the present invention, after local debridement, powder of the present invention is modulated into to the pasty state unguentum with Oleum sesami, is coated on wound surface and pours into sinus tract, changed dressings once in 1st, the wound surface purulent secretion obviously reduces, wound surface incrustation after 14 days, sinus tract closure after 21 days, wound healing.
Lee * *, female, 15 years old, the left leg insect-bite, local red and swollen broken knot, the shiver with cold of companion's whole body, heating, wound surface is sterile-processed, local external application powder of the present invention (the pasty state unguentum that is modulated into Chinese medicine of the present invention and 0.9% normal saline), after three days, redness disappears, General Symptoms is clearly better, the red and swollen disappearance after five days, recovery from illness.
Poplar * *, man, 17 years old, the shallow ∏ degree of left forearm 3% is scalded, severe pain, there is blister part, and wound surface is red, part is cleaned with hydrogen peroxide, powder of the present invention and Oleum sesami are spread on to wound surface by 45:55 adjustment paste making agent, and pain obviously alleviates, and the next day changes dressings once, wound healing after 6 days, do not stay pigmentation and cicatrix.
Open XX, the female, 82 years old, suffer from the arterial obliterans of lower extremity more than two decades, two lower limb were walked lamely more than ten years, carrying out property increases the weight of, two numbness of lower limbs fear of cold, and left sufficient cold injury, wound surface size 3cmx3.5cm, wound surface is pale, red and swollen on every side, common changing dressings 2 months, wound is prolonged does not heal, and wound surface enlarges gradually.Through debridement, and adopt powder of the present invention to spread on wound surface, the next day, change dressings, and after the week, wound surface is reduced into 2cmx2cm gradually, through 3 weeks, adopts this powder to change dressings, and wound is fully recovered gradually, in two years not recurrence.
Claims (6)
1. Chinese medicine for the treatment of wound and bran urine foot disease ulcer, it is characterized in that: the raw material of described Chinese medicine forms and the mass parts ratio is: RHIZOMA BISTORTAE 1~2.5; Rhizoma Paridis 0.8~1.5; Rhizoma Arisaematis (processed) 0.5~1; Rhizoma Kaempferiae 0.5~2; Radix Arnebiae (Radix Lithospermi) 0.5~1.
2. a kind of Chinese medicine for the treatment of wound and bran urine foot disease ulcer according to claim 1, it is characterized in that: the raw material of described Chinese medicine forms and the mass parts ratio is: RHIZOMA BISTORTAE 2; Rhizoma Paridis 1; Rhizoma Arisaematis (processed) 1; Rhizoma Kaempferiae 1; Radix Arnebiae (Radix Lithospermi) 0.5.
3. the described a kind of preparation method for the treatment of the Chinese medicine of wound and bran urine foot disease ulcer of claim 1 or 2, is characterized in that: in the mass parts ratio, take RHIZOMA BISTORTAE, Rhizoma Paridis, Rhizoma Arisaematis (processed), Rhizoma Kaempferiae and Radix Arnebiae (Radix Lithospermi), be crushed to 100~180 orders after it is mixed, sterilizing, obtain powder.
4. the described a kind of preparation method for the treatment of the Chinese medicine of wound and bran urine foot disease ulcer of claim 3, is characterized in that: by described powder water or edible oil furnishing pasty state, obtain unguentum.
5. the described a kind of preparation method for the treatment of the Chinese medicine of wound and bran urine foot disease ulcer of claim 4, it is characterized in that: described water is normal saline, the mass ratio of described powder and normal saline is 40:60~60:40.
6. the described a kind of preparation method for the treatment of the Chinese medicine of wound and bran urine foot disease ulcer of claim 4, it is characterized in that: described oil is Oleum sesami or Adeps Sus domestica, the mass ratio of described powder and Oleum sesami is 45:55~55:45, and the mass ratio of described powder and Adeps Sus domestica is 35:65~55:45.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310318451.5A CN103394009B (en) | 2013-07-26 | 2013-07-26 | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310318451.5A CN103394009B (en) | 2013-07-26 | 2013-07-26 | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103394009A true CN103394009A (en) | 2013-11-20 |
| CN103394009B CN103394009B (en) | 2014-05-07 |
Family
ID=49557862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310318451.5A Expired - Fee Related CN103394009B (en) | 2013-07-26 | 2013-07-26 | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103394009B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029072A (en) * | 2017-06-19 | 2017-08-11 | 江斌 | A kind of Hibisci Paste with antiinflammatory action |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1375306A (en) * | 2001-03-20 | 2002-10-23 | 王文安 | Sanhuanggao ointment as externally used medicine for treating burns and scalds |
-
2013
- 2013-07-26 CN CN201310318451.5A patent/CN103394009B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1375306A (en) * | 2001-03-20 | 2002-10-23 | 王文安 | Sanhuanggao ointment as externally used medicine for treating burns and scalds |
Non-Patent Citations (2)
| Title |
|---|
| 南京中医药大学: "《中药大辞典》", 31 March 2006 * |
| 宋兆友: "常用皮肤病中药外用制剂介绍", 《皮肤病与性病》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029072A (en) * | 2017-06-19 | 2017-08-11 | 江斌 | A kind of Hibisci Paste with antiinflammatory action |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103394009B (en) | 2014-05-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102327478B (en) | Pharmaceutical composition for treating burns and scalds and preparation method thereof | |
| CN101791378B (en) | Traditional Chinese medicine preparation for wound hemostasis, anti-inflammatory and tissue regeneration | |
| CN101049466B (en) | Ointment of Chinese herbal medicine for treating burn and scald without pain, and scar, and preparation method | |
| CN101249215B (en) | Medicine for curing burn dressing and method of preparing the same | |
| CN102357203B (en) | Cortex ulmis burn ointment for curing burns | |
| CN101199754B (en) | Medicament for treating trauma bleeding, body surface and part cavity film inflammation and preparing method thereof | |
| CN103845578B (en) | Treatment burn and scald, decubital ulcer, herpes zoster external-use tincture and preparation method | |
| CN101869636B (en) | Sinkiang arnebia oil cream | |
| CN103446240B (en) | Traditional Chinese medicine composition for rapidly healing wounds | |
| CN103417781B (en) | A kind of Chinese medicine for the treatment of surgical wound | |
| CN103394009B (en) | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method | |
| CN104689132A (en) | Traditional Chinese medicine composition for treating psoriasis | |
| CN104547251B (en) | A kind of navel patch and preparation method for treating chordapsus | |
| CN102872187A (en) | External carbuncle cream and preparation method thereof | |
| CN109045204A (en) | A kind of herb liquid and preparation method thereof for treating burn and scald | |
| CN103142727B (en) | Chinese herbal medicine composition for treating burning and scalding of human body | |
| CN105770347A (en) | Pure traditional Chinese medicinal oil for burns, scalds, wounds and ulcers and preparation method of pure traditional Chinese medicinal oil | |
| CN104306734B (en) | Treat diabetic gangrene externally applied ointment preparation and preparation method thereof | |
| CN102920818B (en) | Formula of medicine for treating burn, scald and cold injury | |
| CN102451249B (en) | Drug for treating burn and scald, and application thereof | |
| CN102824599B (en) | Traditional Chinese medicine tincture for treating various skin eruptions caused by diabetes | |
| CN103479917B (en) | Traditional Chinese medicine composition for treating burns and scalds | |
| CN106668295A (en) | Externally-used medicine for treating psoriasis, and preparation method of externally-used medicine | |
| CN101095752B (en) | Chinese traditional medicine for treating burn and scald | |
| CN104825629A (en) | Traditional Chinese medicine compound externally-applied coating liquid for treatment of diabetic foot ulcers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140507 Termination date: 20180726 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |