CN103330887B - 一种治疗产后恶露不绝的药物组合物 - Google Patents
一种治疗产后恶露不绝的药物组合物 Download PDFInfo
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Abstract
本发明涉及一种治疗产后恶露不绝的药物组合物，它由下述重量配比的物质制成：紫河车、熟地黄、翼首草、山慈菇、决明子、绵萆薢、女贞子、百部、小驳骨、射干、桔梗、菥蓂、紫花前胡、桑寄生、马齿苋、使君子、小通草、暴马子皮、葛根、龙脷叶、木棉花、黄芩、余甘子、杠板归、木蝴蝶、萹蓄、桑白皮、荔枝核、五倍子、石榴皮、花椒、闹羊花、翻白草和菊花。本发明所述的治疗产后恶露不绝的药物组合物具有成本低、制备易、毒副作用小、疗效显着的特点。
Description
技术领域
本发明涉及药物领域，具体地说，涉及一种治疗产后恶露不绝的药物组合物。
背景技术
妇人分娩后，胞宫内残留的余血和浊液称为恶露。若在产后3周，引产后或药物流产后半月，或人工流产后1周以上仍淋漓不断者，则属病理现象，称为恶露不绝。现代医学认为，产后恶露不绝多与部分胎盘、胎膜残留或胎盘附着部位感染，使局部不能正常复原，影响子宫收缩而致。
发明内容
本发明的目的是提供一种治疗产后恶露不绝的药物组合物。
为了实现本发明的目的，本发明提供一种治疗产后恶露不绝的药物组合物，它由下述重量配比的物质制成：紫河车23份、熟地黄17份、翼首草33份、山慈菇21份、决明子30份、绵萆薢14份、女贞子27份、百部26份、小驳骨23份、射干19份、桔梗13份、菥蓂26份、紫花前胡13份、桑寄生19份、马齿苋27份、使君子34份、小通草23份、暴马子皮26份、葛根28份、龙脷叶17份、木棉花23份、黄芩36份、余甘子17份、杠板归24份、木蝴蝶26份、萹蓄11份、桑白皮17份、荔枝核18份、五倍子24份、石榴皮18份、花椒18份、闹羊花15份、翻白草16份和菊花34份。
优选地，所述药物组合物可以为片剂、分散片、散剂或汤剂。
本发明所述的治疗产后恶露不绝的药物组合物具有成本低、制备易、毒副作用小、疗效显着的特点。
具体实施方式
实施例1：
称取紫河车23克、熟地黄17克、翼首草33克、山慈菇21克、决明子30克、绵萆薢14克、女贞子27克、百部26克、小驳骨23克、射干19克、桔梗13克、菥蓂26克、紫花前胡13克、桑寄生19克、马齿苋27克、使君子34克、小通草23克、暴马子皮26克、葛根28克、龙脷叶17克、木棉花23克、黄芩36克、余甘子17克、杠板归24克、木蝴蝶26克、萹蓄11克、桑白皮17克、荔枝核18克、五倍子24克、石榴皮18克、花椒18克、闹羊花15克、翻白草16克和菊花34克，加入6000毫升水，在80℃下加热3小时，过滤。向滤渣中加入3000毫升水，在70℃下加热2小时，过滤。合并两次过滤所得的滤液，浓缩至500毫升，即得本发明所述的汤剂。
实验例
1.1一般资料
选取患者80例，年龄22-39岁，平均年龄30.5岁；发生于剖宫产后26例，足月顺产后17例，中孕引产后12例，人工流产后6例，药物流产后19例；B超检查宫内有胚胎残留物者23例；阴道流血时间9-40d，平均时间24.5d。所有患者经血常规及肝功能检查排除凝血功能障碍所致的出血。
1.2诊断标准
参照《中医妇科学》(罗元恺.中医妇科学.上海：上海科学技术出版社，1986；134)的相关内容，中医辨证属气虚血瘀型。症见：产后恶露过期不止，量多或淋漓不断或涩滞不爽，色淡红、质稀薄或色暗有块并伴小腹疼痛，舌淡或暗红，脉弱或沉弦。
使用实施例1中制备的汤剂来进行治疗。每次口服80毫升，每天3次，连续治疗10天为1个疗程。
1.3疗效评定标准参照《中医病证诊断疗效标准》(国家中医药管理局.中医病证诊断疗效标准.南京：南京大学出版社.1994：247)。治愈：服药后7d内恶露停止，临床症状消失；好转：服药后7d内恶露减少，临床症状明显改善；未愈：与治疗前相比，各方面均无改善。
1.4观察指标
观察治疗前后临床症状改善情况；治疗前有胚胎残留者，停药后复查B超以观察宫内残留物排出情况。
经过治疗，80例患者服药后7d内恶露停止，临床症状消失，因此完全符合治愈的疗效标准，并且在治疗过程中未观察到明显的不良反应。
Claims (1)
1.一种治疗产后恶露不绝的药物组合物，其特征在于它由下述重量配比的物质制成：紫河车23份、熟地黄17份、翼首草33份、山慈菇21份、决明子30份、绵萆薢14份、女贞子27份、百部26份、小驳骨23份、射干19份、桔梗13份、菥蓂26份、紫花前胡13份、桑寄生19份、马齿苋27份、使君子34份、小通草23份、暴马子皮26份、葛根28份、龙脷叶17份、木棉花23份、黄芩36份、余甘子17份、杠板归24份、木蝴蝶26份、萹蓄11份、桑白皮17份、荔枝核18份、五倍子24份、石榴皮18份、花椒18份、闹羊花15份、翻白草16份和菊花34份。
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