CN103301203A - Traditional Chinese medicine essence for eyeground diseases and preparation method thereof - Google Patents
Traditional Chinese medicine essence for eyeground diseases and preparation method thereof Download PDFInfo
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- CN103301203A CN103301203A CN201310288117XA CN201310288117A CN103301203A CN 103301203 A CN103301203 A CN 103301203A CN 201310288117X A CN201310288117X A CN 201310288117XA CN 201310288117 A CN201310288117 A CN 201310288117A CN 103301203 A CN103301203 A CN 103301203A
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Abstract
The invention discloses traditional Chinese medicine essence for eyeground diseases and a preparation method thereof. The traditional Chinese medicine essence is extracted from a mixture of ash barks, butterfly bush flowers inula and red sage roots. An extraction process comprises the steps of weighing traditional Chinese medicine raw materials according to a ratio, cleaning the raw materials, sun-drying the raw materials for standby, mixing and crushing the standby traditional Chinese medicine raw materials, adding water to form crushed mud, heating the crushed mud to the temperature of 100 DEG C, decocting for 40 min, filtering the decoction to obtain traditional Chinese medicine liquid, cooling the traditional Chinese medicine liquid, mixing additives with the cooled traditional Chinese medicine liquid, stirring for a period of time, adjusting the pH to be 4.0 by using edible acetic acid, standing for a day, and drying the liquid subjected to standing, thereby obtaining the dry powdery traditional Chinese medicine essence for eyeground diseases. The traditional Chinese medicine essence disclosed by the invention has the advantages that active ingredients, acting on eye disease treatment and blood circulation invigorating and blood stasis dispelling, of the ash barks, the butterfly bush flowers and the red sage roots are concentrated effectively, the blood circulation of the eye region can be promoted effectively, various functional indicators of the eye region are improved greatly, and the eyesight is improved. Furthermore, the extraction process of the traditional Chinese medicine essence is simple in step, convenient in implementation and higher in extraction rate, and is applicable to large-scale batch production.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine and method for making thereof, relate in particular to a kind of for retinopathy auxiliary treatment used Chinese medicine essence and extraction process thereof.
Background technology
At present, in numerous human body diseases ophthalmic often people very important, have a strong impact on life, work important diseases.Retinopathy typically refers to the pathological changes of retina, choroid and optic nerve.Retinopathy is not mostly seen red, is kept in dark place, the symptom of pain, and main manifestations is visual disorder.Chinese medicine is thought: part retinopathy and general disease have close relationship.
Summary of the invention
In view of the demand that above-mentioned prior art exists, the objective of the invention is to propose a kind ofly to prevent and treat the Chinese medicine essence that retinopathy achieves noticeable achievement, and propose the method for making of the higher Chinese medicine essence of a kind of effective ingredient extraction.
One of above-mentioned purpose of the present invention retinopathy Chinese medicine essence, its technical scheme that is achieved is: described Chinese medicine essence is for extracting the dry powder attitude medicine from Cortex Fraxini, Flos Buddlejae and Radix Salviae Miltiorrhizae arbitrary proportion mixture.
Further, described mixture component by weight is: 50 parts of Cortex Fraxinis, 30 parts of Flos Buddlejaes, 20 parts of Radix Salviae Miltiorrhizaes.
Further, described mixture component by weight is: 35 parts of Cortex Fraxinis, 40 parts of Flos Buddlejaes, 25 parts of Radix Salviae Miltiorrhizaes.
Further, described mixture component by weight is: 30 parts of Cortex Fraxinis, 35 parts of Flos Buddlejaes, 35 parts of Radix Salviae Miltiorrhizaes.
The extraction process of two retinopathy Chinese medicine essences of above-mentioned purpose of the present invention, its technical scheme that is achieved comprises operating procedure: I, take by weighing Cortex Fraxini, Flos Buddlejae and three kinds of raw material of Chinese medicine of Radix Salviae Miltiorrhizae, in stainless steel tank, carry out routine and clean, take out dry for subsequent use; II, with raw material of Chinese medicine co-grinding for subsequent use, smashing fineness reaches 200 orders, the water that adds again 12 times of raw material of Chinese medicine gross masses mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 40 minutes, and put into again Filter Press and obtain the herb liquid slurry; IV, indoor at bacteria-and dust-free, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 15-18 ℃, the protease, 0.3% cellulase and 0.2% the diastase that add again three kinds of raw material of Chinese medicine gross weights 0.3%, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into 45 ℃ of electric heating aerator setting constant temperature carried out drying 5 hours, obtain the retinopathy Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is 6% of three kinds of raw material of Chinese medicine gross weights.
Technical scheme of the present invention, its outstanding effect is: this Chinese medicine essence has effectively concentrated Cortex Fraxini and Flos Buddlejae to the active component of curing eye diseases and Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, can effectively promote the ocular blood circulation, significantly improve every function criterion of eye, improve vision.
The specific embodiment
Because at present to the difficult situation of retinopathy treatment present situation, this case creator explores tool for Chinese herbal medicine material, the test of curative effect through concentrated Study of Traditional Chinese Medicine medical knowledge, finally finds preferably technical solution.
After deliberation, the present invention proposes a kind of retinopathy Chinese medicine essence, and it extracts the arbitrary proportion mixture from Cortex Fraxini, Flos Buddlejae and Radix Salviae Miltiorrhizae.
From pharmacology: Cortex Fraxini has the effect of heat clearing and damp drying, liver heat removing and eyesight improving.See: Cortex Fraxini can suppress the aldose reduction of Rat Lens shape thinlyyer, thereby the effect of anti-cataract is arranged.Eye conjunctivitis, herpetic keratitis that the treatment viral infection causes.Compendium of Material Medica record Cortex Fraxini can " go in the order for a long time heat, the swollen pain of two conjunctival congestions ", and Cortex Fraxini can be in order to treat ophthalmic, also can treat uveitis that immunological diseases cause, eye ulcer etc., and is used for long-term chronic renal failure and merges the example obstacle.Cortex Fraxini might the recovered part application of force.
Flos Buddlejae is the common medicine of ophthalmology, and the internal disease of the concurrent ophthalmic of energy is a lot, such as hypertension, diabetes, arteriosclerosis etc.Many immunological diseases also have certain infringement to eyes, easily cause a ulcer and inflammation such as Behcet disease, and ankylosing spondylitis, Ruide disease easily cause uveitis.The contained Phenylpropanoid Glycosides phenolic glycoside constituents of Flos Buddlejae has antioxidant activity; And contained flavonoid acacetin, luteolin and iridoid glycoside constituents all have significant antiinflammatory action.Theory of Chinese medical science: liver opening at eye, liver-QI being connected with eyes, liver store essential substances be in order, normal vision relying on sufficiency of liver-blood.So in medical treatment Liver and kidney method treatment ophthalmic.
Radix Salviae Miltiorrhizae has blood circulation promoting and blood stasis dispelling, cool in nature, the effect that nourishes blood.Radix Salviae Miltiorrhizae can blood fat reducing, atherosclerosis, the liver protecting and ALT lowering, improves immunologic function in the liver, alleviates portal hypertension, improves renal function.Radix Salviae Miltiorrhizae can also improve the liver microcirculation in addition, and unusual transaminase is descended, and alleviates hepatic necrosis, suppresses the hepatic fibrosis hypertrophy, the control liver cirrhosis.
Above three flavor Chinese medicines have the comprehensive function that nourishing the liver is invigorated blood circulation, and by the Chinese medicine essence that extraction process with low cost obtains, can produce the useful curative effect of specific activity.
Further, described mixture component by weight is: 30 parts of Cortex Fraxinis, 35 parts of Flos Buddlejaes, 35 parts of Radix Salviae Miltiorrhizaes.
Embodiment one: a kind of extraction process of retinopathy Chinese medicine essence, it comprises following operating procedure: I, take by weighing 5 jin of Cortex Fraxinis, 3 jin of Flos Buddlejaes and 2 jin of three kinds of raw material of Chinese medicine of Radix Salviae Miltiorrhizae by the quality proportioning, in stainless steel tank, carry out routine and clean, take out dry for subsequent use; II, with raw material of Chinese medicine co-grinding for subsequent use, smashing fineness reaches 200 orders, the water that adds again 100 jin mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 30 minutes, and put into again Filter Press and obtain the herb liquid slurry; IV, indoor at bacteria-and dust-free, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 15-18 ℃, add again the protease of 0.03 jin of three kinds of raw material of Chinese medicine gross weight, 0.03 jin cellulase and 0.02 jin diastase, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into the electric heating aerator sets 45 ℃ of constant temperature and carried out drying 5 hours, obtain the retinopathy Chinese medicine essence of 0.6 jin of dry powder attitude.
Embodiment two: a kind of extraction process of retinopathy Chinese medicine essence, it comprises following operating procedure: I, take by weighing 7 jin of Cortex Fraxinis, 8 jin of Flos Buddlejaes and 5 jin of three kinds of raw material of Chinese medicine of Radix Salviae Miltiorrhizae by the quality proportioning, in stainless steel tank, carry out routine and clean, take out dry for subsequent use; II, with raw material of Chinese medicine co-grinding for subsequent use, smashing fineness reaches 200 orders, the water that adds again 100 jin mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 30 minutes, and put into again Filter Press and obtain the herb liquid slurry; IV, indoor at bacteria-and dust-free, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 15-18 ℃, add again the protease of 0.06 jin of three kinds of raw material of Chinese medicine gross weight, 0.06 jin cellulase and 0.04 jin diastase, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into the electric heating aerator sets 45 ℃ of constant temperature and carried out drying 5 hours, obtain the retinopathy Chinese medicine essence of 1.2 jin of dry powder attitudes.
Embodiment three: a kind of extraction process of retinopathy Chinese medicine essence, it comprises following operating procedure: I, take by weighing 6 jin of Cortex Fraxinis, 7 jin of Flos Buddlejaes and 7 jin of three kinds of raw material of Chinese medicine of Radix Salviae Miltiorrhizae by the quality proportioning, in stainless steel tank, carry out routine and clean, take out dry for subsequent use; II, with raw material of Chinese medicine co-grinding for subsequent use, smashing fineness reaches 200 orders, the water that adds again 100 jin mixes, and produces to pulverize mud; III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 30 minutes, and put into again Filter Press and obtain the herb liquid slurry; IV, indoor at bacteria-and dust-free, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 15-18 ℃, add again the protease of 0.06 jin of three kinds of raw material of Chinese medicine gross weight, 0.06 jin cellulase and 0.04 jin diastase, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours; V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into the electric heating aerator sets 45 ℃ of constant temperature and carried out drying 5 hours, obtain the retinopathy Chinese medicine essence of 1.2 jin of dry powder attitudes.
The embodiment of the invention is intended to be convenient to understand innovation essence of the present invention; but do not limit protection scope of the present invention; all simple modification or equivalence are replaced, or utilize this finished product powder processing and fabricating capsule, pill, injection etc., all should be contained among the scope of the present invention.
Medical record is introduced: retinopathy Chinese medicine extraction element of the present invention is through for many years development, and the input clinical trial, and is evident in efficacy.Law Firm Suzhou Jiangsu Wuzhong District one veteran cadre Wu so-and-so, suffer from retinopathy for many years, seek medical advice everywhere invalid, vision one day was not as one day.Try out afterwards Chinese medicine essence of the present invention, three times on the one, each 2g, miracle has occurred after half a year.Detecting indices through First People's Hospital, city ophthalmologist oculist takes a turn for the better to some extent.
This shows, development and the application of retinopathy Chinese medicine essence of the present invention and extraction process thereof, compare to existing other Chinese medicine semi-finished product or Chinese medicine eating method, this Chinese medicine essence has effectively concentrated Cortex Fraxini and Flos Buddlejae to the active component of curing eye diseases and Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, can effectively promote the ocular blood circulation, significantly improve every function criterion of eye, improve vision, and taking convenience.In addition, extraction process step of the present invention is simple, and it is convenient to implement, and extraction is higher, and being suitable in batches, scale produces.
Claims (5)
1. retinopathy Chinese medicine essence is characterized in that: described Chinese medicine essence is for extracting the dry powder attitude medicine from Cortex Fraxini, Flos Buddlejae and Radix Salviae Miltiorrhizae arbitrary proportion mixture.
2. described retinopathy Chinese medicine essence according to claim 1, it is characterized in that: described mixture component by weight is: 50 parts of Cortex Fraxinis, 30 parts of Flos Buddlejaes, 20 parts of Radix Salviae Miltiorrhizaes.
3. described retinopathy Chinese medicine essence according to claim 1, it is characterized in that: described mixture component by weight is: 35 parts of Cortex Fraxinis, 40 parts of Flos Buddlejaes, 25 parts of Radix Salviae Miltiorrhizaes.
4. described retinopathy Chinese medicine essence according to claim 1, it is characterized in that: described mixture component by weight is: 30 parts of Cortex Fraxinis, 35 parts of Flos Buddlejaes, 35 parts of Radix Salviae Miltiorrhizaes.
5. the extraction process of a retinopathy Chinese medicine essence, its feature comprises operating procedure:
I, take by weighing Cortex Fraxini, Flos Buddlejae and three kinds of raw material of Chinese medicine of Radix Salviae Miltiorrhizae, in stainless steel tank, carry out routine and clean, take out dry for subsequent use;
II, with raw material of Chinese medicine co-grinding for subsequent use, smashing fineness reaches 200 orders, the water that adds again 12 times of raw material of Chinese medicine gross masses mixes, and produces to pulverize mud;
III, will pulverize mud and put into stainless-steel pan, be heated to 100 ℃, decoct 40 minutes, and put into again Filter Press and obtain the herb liquid slurry;
IV, indoor at bacteria-and dust-free, herb liquid slurry poured in the stainless-steel pan with agitating device stir, be cooled to 15-18 ℃, the protease, 0.3% cellulase and 0.2% the diastase that add again three kinds of raw material of Chinese medicine gross weights 0.3%, under the condition of 30 beats/mins of rotating speeds, stirred 2 hours, and with tablet vinegar acid for adjusting pH value 4.0, left standstill 24 hours;
V, in aseptic temperature control workshop, the liquid that leaves standstill put into the centrifuge dehydration after, the precipitate that produces is put into 45 ℃ of electric heating aerator setting constant temperature carried out drying 5 hours, obtain the retinopathy Chinese medicine essence of dry powder attitude, the weight of this Chinese medicine essence is 6% of three kinds of raw material of Chinese medicine gross weights.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106977A (en) * | 2009-12-24 | 2011-06-29 | 孟繁英 | Externally-applied sturdy vision eyeshield liquid medicine for preventing and treating oculopathy |
| CN102648968A (en) * | 2011-02-26 | 2012-08-29 | 晏素琼 | External traditional Chinese medicine composition for eye health |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106977A (en) * | 2009-12-24 | 2011-06-29 | 孟繁英 | Externally-applied sturdy vision eyeshield liquid medicine for preventing and treating oculopathy |
| CN102648968A (en) * | 2011-02-26 | 2012-08-29 | 晏素琼 | External traditional Chinese medicine composition for eye health |
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Application publication date: 20130918 |