CN103262998B - Wild lycium ruthenicum tablet and preparation method - Google Patents

Wild lycium ruthenicum tablet and preparation method Download PDF

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Publication number
CN103262998B
CN103262998B CN201310206949.2A CN201310206949A CN103262998B CN 103262998 B CN103262998 B CN 103262998B CN 201310206949 A CN201310206949 A CN 201310206949A CN 103262998 B CN103262998 B CN 103262998B
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China
Prior art keywords
tablet
extract
lycium ruthenicum
screening thing
extraction
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CN201310206949.2A
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Chinese (zh)
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CN103262998A (en
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罗庆春
庄娜
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青海紫阳生物科技有限公司
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Publication of CN103262998A publication Critical patent/CN103262998A/en
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Abstract

The invention belongs to the technical field of depth development of wild lycium ruthenicum and particularly relates to a wild lycium ruthenicum tablet and a preparation method. The wild lycium ruthenicum tablet is prepared by the preparation method comprising the following steps of: (1) raw material sorting; (2) crushing and screening: after crushing, screening through a 50-400-mesh sieve to obtain a screening material; (3) extraction and concentration: submerging by using 10-60% of ethanol and water for extraction to obtain extracting solution slurry; (4) freeze-drying: freeze-drying the extracting solution slurry under the condition of -50 DEG C to -70 DEG C for 5-36 hours; (5) crushing and screening; and (6) tabletting and coating to obtain products. The wild lycium ruthenicum tablet and the preparation method have the advantages that the wild lycium ruthenicum tablet is refined by adopting the wild lycium ruthenicum as the main raw material and adopting an advanced processing technique, and biological active ingredients and trace elements necessary for a human body, such as procyanidins, lycium ruthenicum polysaccharides, protein, vitamin E and vitamin C, in the wild lycium ruthenicum are effectively retained, so that the wild lycium ruthenicum tablet has a very high nutritional value.

Description

Wild black matrimony vine tablet and preparation method
one, technical field:
The invention belongs to the deep development technical field of wild black matrimony vine, particularly the wild black matrimony vine tablet of one and preparation method.
two, technical background:
China is progressively entering into aging society, and health and the health care consciousness of people constantly strengthen, particularly the tonifying kidney and strengthening yang of man, and the beautifying face and moistering lotion consciousness of Ms is more strong, and specific aim nutritious health product demand also will expand further.According to statistics afterwards 5 years in 2004, Chinese nutritious health product market will keep high speed development situation on the whole.Nutritious health product market scale will be risen to 683.8 hundred million yuan of 2009 by 34,000,000,000 yuan in 2004, annual average compound growth rate reaches 15.24%, and China will become the healthy fastest-rising market of product of worldwide nutrition.The world top economist Paul Pilzer estimates that health industry in 2010 is every year for America's economy brings the income of a trillion dollars, and these incomes make us more healthy, more beautiful from providing for masses, delay senility or prophylactic product etc.Health industry does not exist before Two decades years, but today, health industry income was every year more than 200,000,000,000 dollars, be equivalent to the half of U.S.'s integral automobile industry income, a trillion dollars will be risen to by 200,000,000,000 by the consumption in health industry in 2000 to 2010, foot has the growth of five times, and this has absolutely proved that today that health product focuses on quality of life people has wide market prospects.The wild black matrimony vine that the enterprise of the applicant develops, brand name is golden black mole, and its growth is badly dry, as the desert region, plateau of 3000 meters of height above sea level of Chaidamu Basin, Qinghai Province, pollution-free, and environment is clean.Bioactive ingredients containing a large amount of needed by human such as LBP-X, Flavonoid substances, protein, vitamin E, vitamin C in wild black matrimony vine and trace element, particularly it is also containing higher OPC, be called for short OPC, being a kind of bioflavonoid having special molecular structure, is the most effective natural of removing people interior free yl of generally acknowledging in the world at present.It is red-brown powder, and gas is micro-, puckery, water-soluble and most organic solvent, is the new and effective antioxidant of one of generally acknowledging in the world at present, is also the most potent found so far free radical scavenger, has very strong activity in vivo.Experiment proves, the Green Tea Extract oxidability of OPC is 50 times of vitamin E, ascorbic 20 times, and absorbs rapidly completely, and within oral 20 minutes, can reach the highest haemoconcentration, metabolic half life is for 7 hours.Also be not effectively utilized this precious resources at present, how effectively utilizing health care that wild this precious resources of black matrimony vine is the mankind and health service is one of problem of researching and solving of people.
three, summary of the invention:
The object of the invention is the huge market has openings to health product for existing social being, and utilize wild this precious resources of black matrimony vine targetedly, development one has extensive market prospects, and there is tonifying kidney and strengthening yang, the wild black matrimony vine tablet of skin maintenance effect and preparation method, thus meet the market demand of people to health product.The wild black matrimony vine tablet that the present invention develops and preparation method adopt wild black matrimony vine to be primary raw material, adopt the wild black matrimony vine tablet that advanced processing technology is refined, effectively remain the OPC in wild black matrimony vine, LBP-X, protein, vitamin E, the bioactive ingredients of the needed by human such as vitamin C and trace element, human body has high nutritive value after taking, be applicable to need to regulate its function of immune system, antifatigue, improve liver-kidney Yin deficiency, soreness and weakness of waist and knees, tonifying kidney and strengthening yang, beautifying face and moistering lotion, the crowd such as delay senility, it is the good merchantable brand of pure natural health preserving and present, its economic and social benefit is very remarkable.
Its technical scheme is: wild black matrimony vine tablet of the present invention, is obtained by following preparation method:
(1). raw material is chosen: the impurity removing the carpopodium in raw material wild black matrimony vine, impurity, immature fruit, broken fruit and wormy fruit; (2). crush and screen: after pulverizing, sieve to obtain screening thing by 50-400 mesh sieve; (3). extract concentrated: with the ethanol of 10-60%, screening thing is flooded extraction 1-5 time, with water, the screening thing after alcohol extract is flooded extraction 1-6 time more again, each extraction time is 5-120 minute, merge all extracts, solids removed by filtration material, again the extract after filtration is concentrated, obtain extract slurry; (4). freeze-drying: extract slurry is at-50 DEG C--freeze drying 5-36 hour under 70 DEG C of conditions, to remove remaining partial solvent and to make it be easy to pulverize; (5). crush and screen: sieved by 50-400 mesh sieve after the solids after freezing is pulverized and to obtain screening thing; (6). compress tablet coating obtains product: screening thing carry out compressing tablet again dressing namely obtain product, the pressure of compressing tablet is not less than 90,000 Ns, dressing number of times 3-8 time.In order to improve the nutritional labeling of product further, also can obtain in product sequence at compress tablet coating the nutritional supplements adding other, as carbohydrate, salt, plant additive, vitamin etc.
Tool of the present invention has the following advantages: the wild black matrimony vine tablet that the present invention develops and preparation method adopt wild black matrimony vine to be primary raw material, adopt the wild black matrimony vine tablet that advanced processing technology is refined, effectively remain the OPC in wild black matrimony vine, LBP-X, protein, vitamin E, the bioactive ingredients of the needed by human such as vitamin C and trace element, human body has high nutritive value after taking, be applicable to need to regulate its function of immune system, antifatigue, improve liver-kidney Yin deficiency, soreness and weakness of waist and knees, tonifying kidney and strengthening yang, beautifying face and moistering lotion, the crowd such as delay senility, it is the good merchantable brand of pure natural health preserving and present.
four, specific embodiments:
Embodiment 1: wild black matrimony vine tablet of the present invention, is obtained by following preparation method:
(1). raw material is chosen: the impurity removing the carpopodium in raw material wild black matrimony vine, impurity, immature fruit, broken fruit and wormy fruit; (2). crush and screen: after pulverizing, sieve to obtain screening thing by the sieve about 50 orders; (3). extract concentrated: by concentration be 60% ethanol screening thing is flooded extraction 5 times, each extraction time is 5 minutes, with water, the screening thing after alcohol extract is flooded extraction 1 time more again, each extraction time is 120 minutes, merge all extracts, solids removed by filtration material, then the extract after filtering is concentrated, obtain extract slurry; (4). freeze-drying: extract slurry freeze drying 36 hours under about-50 DEG C conditions, to remove remaining partial solvent and to make it be easy to pulverize; (5). crush and screen: sieved by the sieve about 50 orders after the solids after freezing is pulverized and to obtain screening thing; (6). compress tablet coating obtains product: screening thing carry out compressing tablet again dressing namely obtain product, the pressure of compressing tablet is not less than 91,000 Ns, dressing number of times 3 times.
Embodiment 2: wild black matrimony vine tablet of the present invention, is obtained by following preparation method:
(1). raw material is chosen: the impurity removing the carpopodium in raw material wild black matrimony vine, impurity, immature fruit, broken fruit and wormy fruit; (2). crush and screen: after pulverizing, sieve to obtain screening thing by 400 mesh sieve; (3). extract concentrated: by concentration be 10% ethanol screening thing is flooded extraction 1 time, each extraction time is 120 minutes, with water, the screening thing after alcohol extract is flooded extraction 6 times more again, each extraction time is 5 minutes, merge all extracts, solids removed by filtration material, then the extract after filtering is concentrated, obtain extract slurry; (4). freeze-drying: extract slurry freeze drying 5 hours under-70 DEG C of conditions, to remove remaining partial solvent and to make it be easy to pulverize; (5). crush and screen: sieved by the sieve about 400 orders after the solids after freezing is pulverized and to obtain screening thing; (6). compress tablet coating obtains product: screening thing carry out compressing tablet again dressing namely obtain product, the pressure of compressing tablet is not less than 120,000 Ns, dressing number of times 8 times.In order to improve the nutritional labeling of product further, can obtain in product sequence at compress tablet coating the nutritional supplements honey adding other.
Embodiment 3: wild black matrimony vine tablet of the present invention, is obtained by following preparation method:
(1). raw material is chosen: the impurity removing the carpopodium in raw material wild black matrimony vine, impurity, immature fruit, broken fruit and wormy fruit; (2). crush and screen: after pulverizing, sieve to obtain screening thing by the sieve about 200 orders; (3). extract concentrated: by concentration be 45% ethanol screening thing is flooded extraction 3 times, each extraction time is 60 minutes, with water, the screening thing after alcohol extract is flooded extraction 3 times more again, each extraction time is 70 minutes, merge all extracts, solids removed by filtration material, then the extract after filtering is concentrated, obtain extract slurry; (4). freeze-drying: extract slurry is freeze drying 24 hours under-60 DEG C of conditions, to remove remaining partial solvent and to make it be easy to pulverize; (5). crush and screen: sieved by the sieve about 250 orders after the solids after freezing is pulverized and to obtain screening thing; (6). compress tablet coating obtains product: screening thing carry out compressing tablet again dressing namely obtain product, the pressure of compressing tablet is 150,000 Ns, dressing number of times 5 times, in order to improve the nutritional labeling of product further, obtains in product sequence the nutritional supplements salt adding other at compress tablet coating.

Claims (2)

1. a wild black matrimony vine tablet, is characterized in that it is obtained by following preparation method: (1). raw material is chosen: remove the carpopodium in the wild black matrimony vine of raw material, impurity, immature fruit, broken fruit and wormy fruit; (2). crush and screen: after pulverizing, sieve to obtain screening thing by 50-400 mesh sieve; (3). extract concentrated: with the ethanol of 10-60%, screening thing is flooded extraction 1-5 time, with water, the screening thing after alcohol extract is flooded extraction 1-6 time more again, each extraction time is 5-120 minute, merge all extracts, solids removed by filtration material, again the extract after filtration is concentrated, obtain extract slurry; (4). freeze-drying: extract slurry is at-50 DEG C--freeze drying 5-36 hour under 70 DEG C of conditions; (5). crush and screen: sieved by 50-400 mesh sieve after the solids after freezing is pulverized and to obtain screening thing; (6). compress tablet coating obtains product: screening thing carry out compressing tablet again dressing namely obtain product, the pressure of compressing tablet is not less than 90,000 Ns, dressing number of times 3-8 time.
2. a preparation method for wild black matrimony vine tablet, is characterized in that: (1). raw material is chosen: remove the carpopodium in the wild black matrimony vine of raw material, impurity, immature fruit, broken fruit and wormy fruit; (2). crush and screen: after pulverizing, sieve to obtain screening thing by 50-400 mesh sieve; (3). extract concentrated: with the ethanol of 10-60%, screening thing is flooded extraction 1-5 time, with water, the screening thing after alcohol extract is flooded extraction 1-6 time more again, each extraction time is 5-120 minute, merge all extracts, solids removed by filtration material, again the extract after filtration is concentrated, obtain extract slurry; (4). freeze-drying: extract slurry is at-50 DEG C--freeze drying 5-36 hour under 70 DEG C of conditions; (5). crush and screen: sieved by 50-400 mesh sieve after the solids after freezing is pulverized and to obtain screening thing; (6). compress tablet coating obtains product: screening thing carry out compressing tablet again dressing namely obtain product, the pressure of compressing tablet is not less than 90,000 Ns, dressing number of times 3-8 time.
CN201310206949.2A 2013-05-30 2013-05-30 Wild lycium ruthenicum tablet and preparation method CN103262998B (en)

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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103892269A (en) * 2014-03-19 2014-07-02 王艺霖 Black medlar sun-screening and whitening tablet
CN103932081B (en) * 2014-03-25 2016-05-18 金诃藏药股份有限公司 Red-black matrimony vine double-layer tablet and preparation method thereof
CN103947967B (en) * 2014-04-21 2015-12-02 青海睿元药物研究所有限责任公司 Double-colored dark red fruit matrimony vine sheet and preparation method thereof
CN103919232A (en) * 2014-05-06 2014-07-16 中国科学院西北高原生物研究所 Lycium ruthenicum effervescent tablet
CN104055936A (en) * 2014-07-11 2014-09-24 郭海涛 Method for preparing lycium barbarum tablet
CN105231447B (en) * 2015-10-28 2018-05-18 青海之也科技咨询服务有限公司 A kind of black fruit fructus lycii health-care tablet for alleviating asthenopia
CN105639644A (en) * 2016-03-29 2016-06-08 北京鑫源鸿泰科技有限公司 Beneficial tasty nutrition lycium ruthenicum murr healthcare composition

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CN101564169A (en) * 2009-05-15 2009-10-28 中国科学院昆明植物研究所 Medlar nutriment, and preparation and application thereof
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