CN103211885A - Chinese medicinal composition for treatment of chronic urticaria - Google Patents

Chinese medicinal composition for treatment of chronic urticaria Download PDF

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CN103211885A
CN103211885A CN2013100937325A CN201310093732A CN103211885A CN 103211885 A CN103211885 A CN 103211885A CN 2013100937325 A CN2013100937325 A CN 2013100937325A CN 201310093732 A CN201310093732 A CN 201310093732A CN 103211885 A CN103211885 A CN 103211885A
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CN103211885B (en
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孙胜波
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孙胜波
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Abstract

The invention relates to a Chinese medicinal composition for treatment of chronic urticaria. The Chinese medicinal composition is made of the following Chinese medicinal materials by weight: 5-25 parts of Puerarin, 5-20 parts of papaya, 10-30 parts of bighead atractylodes rhizome, 5-20 parts of periostracum cicada, 5-20 parts of lumbricus, 5-20 parts of Mangnolia officinalis, 5-20 parts of Schizonepeta, 5-20 parts of cortex moutan, 5-20 parts of red peony roots, 5-20 parts of Great Burdock Achene, 5-25 parts of Salvia miltiorrhiza, 5-15 parts of cassia twigs, 5-25 parts of Fructus Kochiae, 10-30 parts of astragalus, 5-20 parts of Poria cocos, 10-30 parts of Phaseolus Calcaratus, 5-15 parts of Adenophora stricta, 5-20 parts of radix lithospermi, 5-25 parts of Chinese angelica, and 5-15 parts of safflower. With the efficacy of dispelling wind and relieving exterior syndromes, clearing away heat and purging pathogenic fire, strengthening spleen and harmonizing stomach, eliminating dampness and relieving itching, the Chinese medicinal composition has obvious chronic urticaria treatment effects and reliable functions. The Chinese medicinal composition disclosed in the invention has the characteristics of wide ingredient medicine sources, simple preparation, mild medicine properties, and no toxic or side effect.

Description

A kind of Chinese medicine composition for the treatment of chronic urticaria
Technical field
The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of chronic urticaria.
Background technology
Chronic urticaria is a kind of than the common skin disease.Be to cause mucocutaneous blood vessel that temporary inflammatory hyperemia takes place by various factors to ooze out with big quantity of fluid, cause the infringement of local edema.The normal variable interval of patient ground on one's body, on the face or extremity send the erythra piece that a piece is red and swollen and itch very much, usually grab and more itch, grab more swollen and more swollen.Attack times did not once wait to a couple of days for several times from every day.Chronic urticaria is acute often to be broken out, and can occur serious type such as laryngeal edema, gastrointestinal type urticaria when serious, if untimely treatment, but threat to life.At present, Western medicine is treated with antihistamine, amcinonide, and short term effect is sure, and drug withdrawal is easily recurrence then, and Chang Duonian is not healed, and the patient suffering can't bear, and certain side effect is arranged.
The traditional Chinese medical science thinks that the primary disease pathogenesis is a deficiency of YIN-blood, in dyspepsia is arranged, feel exopathogen again, strongly fragrant between the skin space between skin and muscles, evil quadrature is striven and is fallen ill." General Treatise on the Cause and Symptoms of Diseases wind scabies health urticaria time " pointed out: pathogen visitor meets wind and cold to roll over mutually in skin again, the scabies that then blows urticaria... the outer then hyperhidrosis of void of madam's yang-energy, exposure to wind when sweating, pathogenic wind is fought in muscle, with steam also, then give birth to urticaria.Spelt out wind and cold, wind heat visitor in skin, or exterior deficiency, ailment said due to cold or exposure is taken advantage of a weak point in opponent's defence invasion and attack and is caused a disease.
According to theory of Chinese medical science, at the pathogeny of chronic urticaria, carry out dialectical composition of prescription, be the rule of treatment with warming and recuperating the spleen and kidney, circulation of qi promoting dehumidifying, reach the purpose for the treatment of both the principal and the secondary aspects of a disease at the same time.
Summary of the invention
Summary of the invention
Undesirable and the deficiency of side effect is arranged in order to overcome prior art western medicines in treatment chronic urticaria curative effect, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment chronic urticaria that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic urticaria is characterized in that: it is to be made by following parts by weight of Chinese traditional medicine raw material: Radix Puerariae 5-25 part, Fructus Chaenomelis 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Periostracum Cicadae 5-20 part, Pheretima 5-20 part, Cortex Magnoliae Officinalis 5-20 part, Herba Schizonepetae 5-20 part, Cortex Moutan 5-20 part, Radix Paeoniae Rubra 5-20 part, Fructus Arctii 5-20 part, Radix Salviae Miltiorrhizae 5-25 part, Ramulus Cinnamomi 5-15 part, Fructus Kochiae 5-25 part, Radix Astragali 10-30 part, Poria 5-20 part, Semen Phaseoli 10-30 part, Radix Adenophorae (Radix Glehniae) 5-15 part, Radix Arnebiae (Radix Lithospermi) 5-20 part, Radix Angelicae Sinensis 5-25 part, Flos Carthami 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of chronic urticaria is characterized in that: it is to be made by following parts by weight of Chinese traditional medicine raw material: 15 parts of Radix Puerariaes, 12 parts of Fructus Chaenomeliss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Periostracum Cicadaes, 10 parts of Pheretimas, 12 parts of Cortex Magnoliae Officinalis, 10 parts of Herba Schizonepetae, 12 parts of Cortex Moutans, 10 parts of Radix Paeoniae Rubra, 10 parts of Fructus Arctiis, 15 parts of Radix Salviae Miltiorrhizaes, 9 parts of Ramulus Cinnamomi, 15 parts of the Fructus Kochiae, 20 parts of the Radixs Astragali, 10 parts in Poria, 20 parts of Semen Phaseolis, 9 parts of Radix Adenophorae (Radix Glehniae), 10 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Angelicae Sinensis, 6 parts on Flos Carthami.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the Chinese medicine composition of the present invention: Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, analgesic effect of promoting the production of body fluid; Fructus Chaenomelis has the effect of suppressing the hyperactive liver Shujin, stomach function regulating removing dampness; The Rhizoma Atractylodis Macrocephalae has the effect of invigorating the spleen and benefiting QI, dampness diuretic; Periostracum Cicadae has the effect that diffusing wind heat extraction, lung qi dispersing are decided convulsion; Pheretima has the effect of clearing heat for calming endogenous wind, lung heat clearing Dingchuan, inducing diuresis for treating stranguria syndrome, current meridians; Cortex Magnoliae Officinalis has the circulation of qi promoting removing food stagnancy, dampness is removed effect full, lowering the adverse QI to relieve asthma; Herba Schizonepetae has the disappear effect of skin ulcer of the diffusing wind that induces sweat, rash; Cortex Moutan has the effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Radix Paeoniae Rubra has the effect of clearing away heat and cooling blood, eliminating stasis to stop pain; Fructus Arctii has the effect of dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, removing toxic substances and promoting subsidence of swelling; Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Ramulus Cinnamomi has the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; The Fructus Kochiae has heat clearing away, diuresis, itching relieving effect; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating take off admittedly, the effect of wind dispelling fortune poison; Poria has the effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Semen Phaseoli has the effect of inducing diuresis to remove edema, removing toxic substances and promoting pus discharge; Radix Adenophorae (Radix Glehniae) has nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, QI invigorating expectorant effect; Radix Arnebiae (Radix Lithospermi) has the effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, detoxifcation rash; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; Flos Carthami has the effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The selected medicament composing prescription of the present invention, its drug component be through dialectical compatibility, helps using mutual assistant, and the effect of long memorial wind, relieving exterior syndrome, clearing away heat-fire, invigorating the spleen and regulating the stomach, removing dampness to relieve itching reaches treating both the principal and secondary aspects of a disease to treatment of Chronic Urticaria altogether.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.The present invention follows the prescription principle of medication of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, toxic and side effects do not occur, and effective percentage reaches 93.8%, cure rate 57.5%.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of chronic urticaria, it is to be made by following Chinese medicine raw materials by weight proportion: Radix Puerariae 15g, Fructus Chaenomelis 12g, Rhizoma Atractylodis Macrocephalae 20g, Periostracum Cicadae 12g, Pheretima 10g, Cortex Magnoliae Officinalis 12g, Herba Schizonepetae 10g, Cortex Moutan 12g, Radix Paeoniae Rubra 10g, Fructus Arctii 10g, Radix Salviae Miltiorrhizae 15g, Ramulus Cinnamomi 9g, Fructus Kochiae 15g, Radix Astragali 20g, Poria 10g, Semen Phaseoli 20g, Radix Adenophorae (Radix Glehniae) 9g, Radix Arnebiae (Radix Lithospermi) 10g, Radix Angelicae Sinensis 15g, Flos Carthami 6g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of chronic urticaria, it is to be made by following Chinese medicine raw materials by weight proportion: Radix Puerariae 10g, Fructus Chaenomelis 20g, Rhizoma Atractylodis Macrocephalae 15g, Periostracum Cicadae 5g, Pheretima 15g, Cortex Magnoliae Officinalis 10g, Herba Schizonepetae 20g, Cortex Moutan 15g, Radix Paeoniae Rubra 5g, Fructus Arctii 20g, Radix Salviae Miltiorrhizae 10g, Ramulus Cinnamomi 5g, Fructus Kochiae 10g, Radix Astragali 15g, Poria 12g, Semen Phaseoli 30g, Radix Adenophorae (Radix Glehniae) 5g, Radix Arnebiae (Radix Lithospermi) 15g, Radix Angelicae Sinensis 10g, Flos Carthami 5g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of chronic urticaria, it is to be made by following Chinese medicine raw materials by weight proportion: Radix Puerariae 25g, Fructus Chaenomelis 10g, Rhizoma Atractylodis Macrocephalae 30g, Periostracum Cicadae 15g, Pheretima 5g, Cortex Magnoliae Officinalis 20g, Herba Schizonepetae 5g, Cortex Moutan 10g, Radix Paeoniae Rubra 15g, Fructus Arctii 12g, Radix Salviae Miltiorrhizae 25g, Ramulus Cinnamomi 10g, Fructus Kochiae 20g, Radix Astragali 10g, Poria 5g, Semen Phaseoli 20g, Radix Adenophorae (Radix Glehniae) 10g, Radix Arnebiae (Radix Lithospermi) 20g, Radix Angelicae Sinensis 5g, Flos Carthami 15g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of chronic urticaria, it is to be made by following Chinese medicine raw materials by weight proportion: Radix Puerariae 5g, Fructus Chaenomelis 15g, Rhizoma Atractylodis Macrocephalae 25g, Periostracum Cicadae 10g, Pheretima 20g, Cortex Magnoliae Officinalis 5g, Herba Schizonepetae 15g, Cortex Moutan 20g, Radix Paeoniae Rubra 12g, Fructus Arctii 5g, Radix Salviae Miltiorrhizae 20g, Ramulus Cinnamomi 15g, Fructus Kochiae 5g, Radix Astragali 25g, Poria 20g, Semen Phaseoli 10g, Radix Adenophorae (Radix Glehniae) 15g, Radix Arnebiae (Radix Lithospermi) 5g, Radix Angelicae Sinensis 20g, Flos Carthami 10g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of chronic urticaria, it is to be made by following Chinese medicine raw materials by weight proportion: Radix Puerariae 20g, Fructus Chaenomelis 5g, Rhizoma Atractylodis Macrocephalae 10g, Periostracum Cicadae 20g, Pheretima 12g, Cortex Magnoliae Officinalis 15g, Herba Schizonepetae 12g, Cortex Moutan 5g, Radix Paeoniae Rubra 20g, Fructus Arctii 15g, Radix Salviae Miltiorrhizae 5g, Ramulus Cinnamomi 12g, Fructus Kochiae 25g, Radix Astragali 30g, Poria 15g, Semen Phaseoli 15g, Radix Adenophorae (Radix Glehniae) 12g, Radix Arnebiae (Radix Lithospermi) 12g, Radix Angelicae Sinensis 15g, Flos Carthami 12g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15~20 minutes, add water again and do not have about 8 centimetres of powder, decoct, at a simmer preceding employing intense fire decocts, and slow fire boiling 20~30 minutes are used in the back of boiling; Second decocts, and adds water and does not have about 6 centimetres of powder, decocts, and decocts 15~20 minutes after water boils.Decoct extracting juice twice, merge.
A kind of Chinese medicine composition for the treatment of chronic urticaria, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 80 examples, male 31 examples, women 49 examples, 10~60 years old age.
Two, diagnosis basis
1, break out, skin lesion is for differing in size, the edema speckle that shape differs, and boundary is clear;
2, time-out falls during erythra, violent pruritus, and skin lesion appearing without definite location is stepped back and is left no trace;
3, some cases can have abdominal pain diarrhea, or diseases such as heating, arthralgia are arranged.Severe patient can have dyspnea, even causes and suffocate;
4, erythra is not sent out the author through more or repeatedly not being interrupted more than three months.
Three, usage and dosage: during clinical practice, the amounts of components in the compositions is taken the circumstances into consideration increase and decrease according to patient's body weight and age.Potion on the one, the about 300ml of twice extracting juice of decocting divides early, takes for late twice.
Four, criterion of therapeutical effect:
(1) recovery from illness: speckle disappears fully after the medication, and pruritus disappears, and drug withdrawal does not have recurrence after one month;
(2) produce effects: speckle disappears fully after the medication, and pruritus disappears, the back recurrence of a week of drug withdrawal;
(3) effective: attack times reduces, and pruritus alleviates;
(4) invalid; Welt, pruritus are for alleviating.
Five, therapeutic effect: in this clinical observation case, took medicine 1-2 month, 46 examples of fully recovering are followed up a case by regular visits to and are not seen recurrence; Produce effects 19 examples, effective 10 examples, invalid 5 examples.Toxic and side effects does not take place during the treatment.
Six, model case:
Case 1:
Zhang, woman, 43 years old.The rash piece appears in whole body, pruritus, show effect repeatedly 1 year surplus, once took medicines such as loratadine, cetirizine, mizolastine, curative effect is not good enough.During prescription on individual diagnosis, health still has the red rash piece that does not move back, pruritus, fear of cold, weak.Be diagnosed as chronic urticaria.Take the medicament 10 days of Chinese medicine composition of the present invention preparation, symptom obviously alleviates; Continuous clothes 15 days, all symptoms all disappear, recovery from illness.Follow up a case by regular visits to and do not recur half a year.
Case 2:
Liu, man, 29 years old.The skin pale red rash piece that rises after the patient's readme feed seafood food, trunk, extremity distribute and differ in size, and as seen skin scratch trace, disease 3 months repeatedly.Be diagnosed as chronic urticaria.5 days all diseases of medicament of taking Chinese medicine composition preparation of the present invention alleviate; Continuous clothes 7 days and are heal followed up a case by regular visits to and are recurred half a year again.

Claims (2)

1. Chinese medicine composition for the treatment of chronic urticaria, it is characterized in that: it is to be made by following parts by weight of Chinese traditional medicine raw material: Radix Puerariae 5-25 part, Fructus Chaenomelis 5-20 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Periostracum Cicadae 5-20 part, Pheretima 5-20 part, Cortex Magnoliae Officinalis 5-20 part, Herba Schizonepetae 5-20 part, Cortex Moutan 5-20 part, Radix Paeoniae Rubra 5-20 part, Fructus Arctii 5-20 part, Radix Salviae Miltiorrhizae 5-25 part, Ramulus Cinnamomi 5-15 part, Fructus Kochiae 5-25 part, Radix Astragali 10-30 part, Poria 5-20 part, Semen Phaseoli 10-30 part, Radix Adenophorae (Radix Glehniae) 5-15 part, Radix Arnebiae (Radix Lithospermi) 5-20 part, Radix Angelicae Sinensis 5-25 part, Flos Carthami 5-15 part.
2. a kind of Chinese medicine composition for the treatment of chronic urticaria according to claim 1 is characterized in that: it is to be made by following parts by weight of Chinese traditional medicine raw material: 15 parts of Radix Puerariaes, 12 parts of Fructus Chaenomeliss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Periostracum Cicadaes, 10 parts of Pheretimas, 12 parts of Cortex Magnoliae Officinalis, 10 parts of Herba Schizonepetae, 12 parts of Cortex Moutans, 10 parts of Radix Paeoniae Rubra, 10 parts of Fructus Arctiis, 15 parts of Radix Salviae Miltiorrhizaes, 9 parts of Ramulus Cinnamomi, 15 parts of the Fructus Kochiae, 20 parts of the Radixs Astragali, 10 parts in Poria, 20 parts of Semen Phaseolis, 9 parts of Radix Adenophorae (Radix Glehniae), 10 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Angelicae Sinensis, 6 parts on Flos Carthami.
?
CN201310093732.5A 2013-03-22 2013-03-22 Chinese medicinal composition for treatment of chronic urticaria Expired - Fee Related CN103211885B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103393834A (en) * 2013-08-05 2013-11-20 谢明臣 Prescription for treatment of urticaria
CN103919990A (en) * 2014-04-22 2014-07-16 广州中医药大学 Traditional Chinese medicine composition, as well as preparation method and applications thereof
CN103989993A (en) * 2014-05-12 2014-08-20 宁波大学 Pharmaceutical preparation used for treating cold urticaria
CN103989994A (en) * 2014-05-12 2014-08-20 宁波大学 Pharmaceutical preparation for treating chronic urticaria
CN104758729A (en) * 2015-04-26 2015-07-08 王伟伟 Traditional Chinese medicine composition for treating chronic urticaria
CN106798848A (en) * 2017-02-14 2017-06-06 四川双鑫生物科技有限公司 A kind of endo-medicine and preparation method for treating chronic urticaria

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CN101985009A (en) * 2010-07-02 2011-03-16 荣成市科学技术情报研究所 Chinese medicinal composition for treating chronic urticaria
CN102370914A (en) * 2011-10-21 2012-03-14 马良玉 Oral Chinese patent medicine pill for treating urticaria

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103393834A (en) * 2013-08-05 2013-11-20 谢明臣 Prescription for treatment of urticaria
CN103919990A (en) * 2014-04-22 2014-07-16 广州中医药大学 Traditional Chinese medicine composition, as well as preparation method and applications thereof
CN103919990B (en) * 2014-04-22 2017-01-11 广州中医药大学 Traditional Chinese medicine composition, as well as preparation method and applications thereof
CN103989993A (en) * 2014-05-12 2014-08-20 宁波大学 Pharmaceutical preparation used for treating cold urticaria
CN103989994A (en) * 2014-05-12 2014-08-20 宁波大学 Pharmaceutical preparation for treating chronic urticaria
CN104758729A (en) * 2015-04-26 2015-07-08 王伟伟 Traditional Chinese medicine composition for treating chronic urticaria
CN106798848A (en) * 2017-02-14 2017-06-06 四川双鑫生物科技有限公司 A kind of endo-medicine and preparation method for treating chronic urticaria

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