CN103141705B - Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period - Google Patents

Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period Download PDF

Info

Publication number
CN103141705B
CN103141705B CN201310111919.3A CN201310111919A CN103141705B CN 103141705 B CN103141705 B CN 103141705B CN 201310111919 A CN201310111919 A CN 201310111919A CN 103141705 B CN103141705 B CN 103141705B
Authority
CN
China
Prior art keywords
weight portions
weight portion
weight
feed additive
portions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201310111919.3A
Other languages
Chinese (zh)
Other versions
CN103141705A (en
Inventor
吕明斌
燕磊
唐婷婷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHENGDU CENTURY INVESTMENT Co.,Ltd.
Original Assignee
Shandong New Hope Liuhe Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong New Hope Liuhe Group Co Ltd filed Critical Shandong New Hope Liuhe Group Co Ltd
Priority to CN201310111919.3A priority Critical patent/CN103141705B/en
Publication of CN103141705A publication Critical patent/CN103141705A/en
Application granted granted Critical
Publication of CN103141705B publication Critical patent/CN103141705B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a traditional Chinese medicine feed additive for improving the immunological competence of dairy cattle in a perinatal period. The traditional medicine feed additive comprises the following bulk drugs: rhizome polygonati, suberect spatholobus stem, astragalus mongholicus, honeysuckle stem, hawthorn, rhizome corydalis, herba andrographitis, stigma croci, radix paeoniae alba, dendrobe, leonurus, fructus psoraleae, polygonum cuspidatum, golden cypress, poria cocos, ligusticum wallichii, Chinese yam, birthwort, fructus choerospondiatis, glossy privet fruit, radix stemonae and liquorice. The therapeutic principle of the traditional Chinese medicine feed additive is invigorating spleen and supplementing qi, replenishing blood, strengthening body resistance and eliminating evil. By feeding dairy cattle with the traditional Chinese medicine feed additive mixed with feeds, the immunological competence of the dairy cattle in the perinatal period can be improved remarkably without toxic and side effect, and the effect is obvious.

Description

For improving the Chinese herbal feed additive of the immunocompetence of cow in perinatal period
Technical field
The present invention relates to Chinese medicine immune formulation technical field, relate in particular to a kind of for improving the Chinese herbal feed additive of the immunocompetence of cow in perinatal period.
Background technology
Refer to the period in antenatal 33 weeks thoughtful postpartum the perinatal period of milk cow, this in period milk cow in stress situation, there is immunosupress in body, the neurological susceptibility of disease increases, therefore, most of communicable diseases and the metabolic disease of milk cow all occur in perinatal period.The generation of these diseases all can reduce the output of milk, affects milk quality, thereby causes huge economic loss to culturist.
Cow in perinatal period experience is a series of stress, as childbirth, lactation, daily ration structural change, environment change etc., due to physiological status, the sharply increase to nutriment demand of anabolic variation and initiation of lactation, capital changes a lot its neuroendocrine and immune state, these all affect the health status of milk cow to a great extent, due to gestation, childbirth and lactation stress, easily make milk cow in immunosuppressive condition, and then there is endometritis in postpartum, mammitis and retention of afterbirth etc., numerous studies confirm that, congenital and the acquired immunity power of cow in perinatal period can be had a strong impact on, remain at low levels, resisting pathogen in exotic invasive and body declines to host's invasive ability, the incidence of disease of Diseases of Cow is much higher than in lactation, later stage.A large amount of results of study confirms, the milk cow that immunity is lower, the probability of morbidity is just higher, if add immunological regulation reinforcing agent in perinatal period, can obviously improve the immunity of this one-phase milk cow, reduce the incidence of disease of milk cow, strengthen the production performance of milk cow, Diseases of Cow immune response to external world reduces, change nonspecific immune reaction, comprise the function that reduces neutrophil cell, reduce lymphopoiesis, reduce antibody quantity and plasmacytic generation.
Chinese herbal medicine is the pure natural substance that the mankind apply the earliest.Check through theory and practice in several thousand, oneself is through determining that Chinese medicine is little to body toxic and side effect, and there is antiviral, antibacterial, anti parasitic, anti-ly stress, increase vitamin and mineral matter and strengthen the effects such as immunity, world's medical treatment Animal diseases in recent years, produce the important directions of green animal product, and many Chinese herbal medicines are used for treating postpartum disease of cow, obtained significant curative effect.
It is principle of reatment that strengthening the spleen and replenishing qi, blood-supplementing blood-nourishing, strengthening vital QI to eliminate pathogenic factors are take in the present invention, provides that a kind of the immunocompetence that it can significantly improve Diseases of Cow, has no side effect for improving the Chinese medicinal composition preparation of the immunocompetence of cow in perinatal period, and effect is remarkable.
Summary of the invention
Technical problem to be solved by this invention is that to take strengthening the spleen and replenishing qi, blood-supplementing blood-nourishing, strengthening vital QI to eliminate pathogenic factors be principle of reatment, provide a kind of for improving the Chinese medicinal composition preparation of the immunocompetence of cow in perinatal period, the immunocompetence that it can significantly improve Diseases of Cow, has no side effect, and effect is remarkable.
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese herbal feed additive that improves the immunologic function of cow in perinatal period, its bulk drug comprises sealwort, reticulate millettia, the Radix Astragali, caulis lonicerae, hawthorn, corydalis tuber, Herba Andrographitis, west safflower, the root of herbaceous peony, the stem of noble dendrobium, motherwort, Psoralea corylifolia, giant knotweed, golden cypress, Poria cocos, Ligusticum wallichii, Chinese yam, birthwort, fructus choerospondiatis, the fruit of glossy privet, the tuber of stemona and Radix Glycyrrhizae.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively: sealwort 55 weight portion ~ 65 weight portions, reticulate millettia 25 weight portion ~ 35 weight portions, the Radix Astragali 85 weight portion ~ 95 weight portions, caulis lonicerae 20 weight portion ~ 30 weight portions, hawthorn 15 weight portion ~ 25 weight portions, corydalis tuber 25 weight portion ~ 35 weight portions, Herba Andrographitis 20 weight portion ~ 30 weight portions, west safflower 30 weight portion ~ 40 weight portions, the root of herbaceous peony 25 weight portion ~ 35 weight portions, the stem of noble dendrobium 40 weight portion ~ 50 weight portions, motherwort 25 weight portion ~ 35 weight portions, Psoralea corylifolia 45 weight portion ~ 55 weight portions, giant knotweed 35 weight portion ~ 45 weight portions, golden cypress 55 weight portion ~ 65 weight portions, Poria cocos 20 weight portion ~ 30 weight portions, Ligusticum wallichii 25 weight portion ~ 35 weight portions, Chinese yam 30 weight portion ~ 40 weight portions, birthwort 15 weight portion ~ 25 weight portions, fructus choerospondiatis 10 weight portion ~ 20 weight portions, the fruit of glossy privet 45 weight portion ~ 55 weight portions, the tuber of stemona 10 weight portion ~ 20 weight portions and Radix Glycyrrhizae 20 weight portion ~ 30 weight portions.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively: sealwort 60 weight portions, reticulate millettia 30 weight portions, the Radix Astragali 90 weight portions, caulis lonicerae 25 weight portions, hawthorn 20 weight portions, corydalis tuber 30 weight portions, Herba Andrographitis 25 weight portions, west safflower 35 weight portions, the root of herbaceous peony 30 weight portions, the stem of noble dendrobium 45 weight portions, motherwort 30 weight portions, Psoralea corylifolia 50 weight portions, giant knotweed 40 weight portions, golden cypress 60 weight portions, Poria cocos 25 weight portions, Ligusticum wallichii 30 weight portions, Chinese yam 35 weight portions, birthwort 20 weight portions, fructus choerospondiatis 15 weight portions, the fruit of glossy privet 50 weight portions, the tuber of stemona 15 weight portions and Radix Glycyrrhizae 25 weight portions.
The present invention also provides the preparation method of above-mentioned Chinese herbal feed additive, be specially: each bulk drug in above-mentioned Chinese herbal feed additive is mixed in proportion, send in mixer and stir 20 minutes ~ 30 minutes, add with respect to 5 ~ 8 times of water of bulk drug quality sum, decoct 2 ~ 4 hours, decoction liquor is filtered, filter residue adds again with respect to 2 ~ 4 times of water of bulk drug quality sum, again decocts 2 ~ 4 hours, and decoction liquor is filtered, filtered fluid is merged, heating is concentrated to be obtained and gets dry extract except anhydrating, and is ground into powder, dry, obtain Chinese herbal feed additive powder.
The present invention also provides a kind of feed, and it comprises: silage corn, dregs of beans, wheat bran and above-mentioned Chinese herbal feed additive.
Wherein, in described feed, the weight portion of each composition is respectively: the weight portion of silage corn is 55 weight portion ~ 65 weight portions, weight portion 13 weight portion ~ 23 weight portions of dregs of beans, the weight portion of wheat bran is 20 weight portion ~ 30 weight portions, and the weight portion of above-mentioned Chinese herbal feed additive is 10 weight portion ~ 16 weight portions.
Wherein, in described feed, can also add antioxidant, the weight portion of described antioxidant in described feed is 2 weight portion ~ 4 weight portions.
Wherein, described antioxidant is vitamin E (V e) and beta carotene in one or both mixing.
Wherein, in described feed, can also add selenium methionine, the weight portion of described selenium methionine in described feed is 0.5 weight portion ~ 1 weight portion.
The present invention also provides the preparation method of above-mentioned feed, is specially:
The first step, prepares Chinese herbal feed additive powder according to the method described above;
Second step, silage corn, dregs of beans, wheat bran ratio are sent into stirrer for mixing, the dry Chinese herbal feed additive powder that adds the first step to obtain, send into the steam modulation 6~7 minutes that passes into 90~100 ℃ in modem, making the moisture after modulation is 12%~14%, then at the temperature of 95~100 ℃, enters extrusion granulator and granulates;
The 3rd step, the pellet after granulating is cooling, packing.
Beneficial effect of the present invention:
It is principle of reatment that Chinese herbal feed additive provided by the invention be take strengthening the spleen and replenishing qi, blood-supplementing blood-nourishing, strengthening vital QI to eliminate pathogenic factors, by it, mixes with feed, and feeding milk cow, can significantly improve the immunocompetence of Diseases of Cow, has no side effect, and effect is remarkable.
The specific embodiment
The invention provides a kind of Chinese herbal feed additive that improves the immunologic function of cow in perinatal period, its bulk drug comprises sealwort, reticulate millettia, the Radix Astragali, caulis lonicerae, hawthorn, corydalis tuber, Herba Andrographitis, west safflower, the root of herbaceous peony, the stem of noble dendrobium, motherwort, Psoralea corylifolia, giant knotweed, golden cypress, Poria cocos, Ligusticum wallichii, Chinese yam, birthwort, fructus choerospondiatis, the fruit of glossy privet, the tuber of stemona and Radix Glycyrrhizae.
Preferably, described Chinese herbal feed additive only consists of above-mentioned raw materials medicine.
In Chinese herbal feed additive, the pharmacology of each bulk drug is as follows:
Sealwort: taste is sweet, property is flat, enters lung, spleen, kidney channel, has the yin-nourishing of fostering the spirit of nobility, invigorating the spleen moistening lung, the effect of enriching kidney essence, for taste deficiency of qi and yin, food is few unable, the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, the quenching one's thirst of yin asthenia generating intrinsic heat, the cards such as deficiency of kidney essence, impotence and seminal emission, dizziness and tinnitus, blurred vision dim eyesight.
Reticulate millettia: bitter, sweet, warm in nature, enter liver, kidney channel, there is hemangiectasis, enrich blood and invigorate blood circulation, menstruation regulating, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, has obvious inhibitory action to platelet aggregation, promote animal kidney and the total phosphorus metabolism in uterus, be mainly used in treating the irregular menstruation that the deficiency of blood has silt, limbs pain is meciless, the cards such as soreness and weakness of waist and knees, pain.
The Radix Astragali: taste is sweet, warm in nature, enter spleen, lung channel, there is help spleen soil, elevate a turnable ladder yang-energy, strengthening exterior and reducing sweat, the effect of holder sore myogenic, cures mainly the weak anorexia and loose stool due to spleen-lung Qi deficiency, palpitation, the visceral organ ptosis of the sinking of qi of middle-jiao, Qi dysfunction in blood control uterine bleeding is had blood in stool, and rushes down for a long time prolapse of the anus; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.The Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and adder-wort peripheral vessel, make skin blood overactive circulation; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect, to staphylococcus, blood dissolubility streptococcus, Diplococcus pneumopniae, shigella dysenteriae etc., have inhibitory action, the Radix Astragali can significantly affect SPL Information Conduction, realize immunoregulation effect.
Caulis lonicerae: taste is sweet, cold in nature, attach to the lung and stomach meridians, have clearing heat and detoxicatingly, the effect of dispelling wind dredging collateral, cures mainly warm disease heating, toxic-heat and blood stasis, the carbuncle sore that swell, rheumatic fever numbness, card such as redness and swelling of joints heat pain grade.
Hawthorn: taste acid, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel, and for food digesting stomach fortifying, the promoting the circulation of qi stasis of blood of fall apart, is mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, hawthorn is the staple for the treatment of indigestion, hawthorn can increase the secretion of peptic digest enzyme, promotes to digest; Shigella dysenteriae, Escherichia coli, Pseudomonas aeruginosa, staphylococcus aureus etc. are had to obvious inhibitory action.
Corydalis tuber: bitter, pungent, warm in nature, return liver, the heart, stomach warp, there is benefaction and wander away, can rise and can fall, have promoting blood circulation to remove blood stasis, the effect of promoting qi circulation and relieving pain, cures mainly chest impediment and cardialgia, the side of body rib, all pains of gastral cavity abdomen, headache, pain in the back, hernia pain, muscle and bone ache, dysmenorrhoea, through closing, postpartum, the stasis of blood was suffered from abdominal pain, the cards such as traumatic injury.
Herba Andrographitis: bitter, cold in nature, the thoughts of returning home, lung, large intestine, urinary bladder channel, have clearing heat and detoxicating, cool blood, detumescence, the effect of eliminating dampness, cures mainly cold, fever, abscess of throat, aphthae, pertussis labor is coughed, dysentery, heat is drenched puckery pain, the carbuncle sore that swells, the cards such as venomous snake bite.
West safflower: taste is sweet, property is flat, can be promoting blood circulation and removing blood stasis, loose Yu Kaijie, pain relieving.Be used for the treatment of troubled thoughts pent-up, chest diaphragm ruffian is vexed, spits blood, and typhoid fever is gone mad, and is frightenedly dimly afraid of, and women is through closing, stasis irregular menstruation, and prolonged lochia, hemostasis is had a pain, measles, the cards such as traumatic injury.
The root of herbaceous peony: bitter, acid, cold nature, returns liver, the spleen channel, has nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, the effect of suppressing liver-YANG, cures mainly the deficiency of blood sallow, irregular menstruation, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, four limbs contraction pain, the dizzy dizzy card that waits.
The stem of noble dendrobium: cold nature, taste is sweet, returns stomach, kidney channel, has reinforcing stomach reg fluid, nourishing Yin and clearing heat effect.Cure mainly the moon and hinder body fluid deficiency, dry polydipsia, food is few retches, abnormal heat after being ill, order is the not clear card that waits secretly.
Motherwort: bitter, pungent, cold nature, enters liver, pericardium channel, has promoting blood circulation for regulating menstruation, and the effect of inducing diuresis to reduce edema, cures mainly irregular menstruation, dysmenorrhoea, through closing, lochiorrhagia, oedema oliguria, the cards such as acute nephritis edema.
Psoralea corylifolia: taste is pungent, bitter, warm in nature, returns kidney, the spleen channel, has tonifying kidney and strengthening yang, and warming spleen and stopping diarrha effect, cures mainly the Yang-function insufficiency of kidneyzang, the waist knee crymodynia of below element deficiency and cold, frequent urination and enuresis, impotence lingering diarrhea; The insufficiency of the kidney yang, spleen soil lose the stomachache limb of temperature and tremble with fear, the cards such as Diarrhoea.
Giant knotweed: micro-hardship, is slightly cold.Return liver, courage, lung channel, have clearing heat and detoxicating, normalizing gallbladder to cure jaundice, expelling wind and removing dampness, loose stasis of blood analgesic therapy, relieving cough and reducing sputum effect, for joint pain, jaundice with damp-heat pathogen, through Bi , wei lump in the abdomen, coughing with a lot of sputum, scald, injury from falling down, the cards such as carbuncle sore tumefacting virus.
Golden cypress: bitter, cold in nature, enter kidney, bladder, large intestine channel, heat-clearing and damp-drying drug, purging intense heat and detonicating, except hectic fever due to yin clearind deficient heat.For damp-heat dysentery, jaundice, under band, heat is drenched, beriberi, and impotence is warded off, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, the cards such as eczema itch, golden cypress has good antibacterial action to multiple gram-positive bacterium.
Poria cocos: taste is sweet, light, property is flat, enters spleen, lung, bladder, the heart channel of Hang-Shaoyin, has the effect of eliminating dampness and diuresis, the peaceful heart of invigorating the spleen, is mainly used in the oedema of retention of water-damp, difficult urination; The heat of damp-heat accumulation is drenched, the cards such as the anorexia and loose stool of water retention due to hypofunction of the spleen, phlegm and retained fluid stagnation, epilepsy.
Ligusticum wallichii: taste is pungent, warm in nature, return liver, courage, pericardium channel, there is blood-activating and qi-promoting, the effect of wind-expelling pain-stopping, cures mainly irregular menstruation; Through closing dysmenorrhoea; The stagnant raw meat pain of the stasis of blood in postpartum; Abdominal mass lump; Pain in chest and hypochondrium; Have a headache dizzy; Wind-cold-dampness arthralgia; Traumatic injury; The cards such as ulcer sores.
Chinese yam: taste is sweet, property is flat, enters lung, spleen, stomach warp, has tonifying spleen nourishing the stomach, and beneficial lung reinforces the kidney, the effect of nourishing Yin and promoting production of body fluid, cure mainly weakness of the spleen and the stomach, the card such as it is poor that the food of the dysfunction of the spleen in transport is received less, the vexed diarrhoea of gastral cavity.
Birthwort: bitter, cold nature, returns lung, large intestine channel, has clearing lung-heat sending down abnormally ascending, relieving cough and asthma, the disappear effect of hemorrhoid of gut purge, for dyspnea and cough due to lung-heat, blood-stained sputum, the hot hemorrhoid blood of intestines, the cards such as hemorrhoid gall.
Fructus choerospondiatis: taste is sweet, sour, property is flat, has the promoting flow of qi and blood circulation, nourishes heart, and calms the nerves, and resists myocardial ischemia, and the effects such as protection heart function, cure mainly qi depression to blood stasis, and the obstruction of qi in the chest is had a pain, palpitation, the confused and worried card that waits.
The fruit of glossy privet: taste is sweet, bitter, is slightly cold, enters liver, kidney channel, has strong liver kidney-nourishing, and the effect of removing heat to brighten vision, is mainly used in treating liver-kidney Yin deficiency, and the head loses foster dizzy tinnitus, the symptoms such as yin asthenia generating intrinsic heat.The fruit of glossy privet can promote leucocyte, strengthens the effect of immunologic function, and staphylococcus aureus, shigella dysenteriae are had to stronger inhibitory action.Modern medicine study proves, the fruit of glossy privet includes ursolic acid, sweet mellow wine, glucose, fatty wet goods, has cardiac stimulant, diuresis and hepatoprotective effect, can make the leucocyte decline quantity causing because of chemotherapy raise, and staphylococcus aureus, Escherichia coli are had to inhibitory action.
The tuber of stemona: taste is sweet, bitter, slightly warm in nature enters lung channel, have and moisten the lung and relieve the cough, the effect of delousing desinsection, tuber of stemona temperature embellishes but not dry, and property is kept and is not walked, the merit that has out again drop-down gas, be mainly used in new all coughing for a long time, be especially suitable for the hot chronic cough person of labor, the modern times are used for preventing and treating the cough of chronic bronchitis, the dry cough of pulmonary tuberculosis, the cards such as pertussis.
Radix Glycyrrhizae: taste is sweet, property is flat, enters 12 warps, has clearing heat and detoxicatingly, is in harmonious proportion the property of medicine, the effect of expelling phlegm and arresting coughing, and can invigorating the spleen and in, relieving spasm to stop pain, is mainly used in weakness of the spleen and the stomach abdominal distension and anorexia, weak; Can alleviate contraction pain in abdomen, relax the strong and toxicity of some drugs, alleviate medicine to the toxic and side effect of body or to GI stimulation, by adding Radix Glycyrrhizae can play tonifying Qi, neutralize, be in harmonious proportion the effect of each component.
Chinese medicine composition effect provided by the invention is extensive, can supplement the nutrients, and increases metabolism, again can antibacterial, antiviral, anti parasitic, regulate the immunity function of body, and to the whole performance of milk cow comprehensive function, there is dual regulation.
In described Chinese herbal feed additive, the weight portion of each bulk drug is respectively: sealwort 55 weight portion ~ 65 weight portions, reticulate millettia 25 weight portion ~ 35 weight portions, the Radix Astragali 85 weight portion ~ 95 weight portions, caulis lonicerae 20 weight portion ~ 30 weight portions, hawthorn 15 weight portion ~ 25 weight portions, corydalis tuber 25 weight portion ~ 35 weight portions, Herba Andrographitis 20 weight portion ~ 30 weight portions, west safflower 30 weight portion ~ 40 weight portions, the root of herbaceous peony 25 weight portion ~ 35 weight portions, the stem of noble dendrobium 40 weight portion ~ 50 weight portions, motherwort 25 weight portion ~ 35 weight portions, Psoralea corylifolia 45 weight portion ~ 55 weight portions, giant knotweed 35 weight portion ~ 45 weight portions, golden cypress 55 weight portion ~ 65 weight portions, Poria cocos 20 weight portion ~ 30 weight portions, Ligusticum wallichii 25 weight portion ~ 35 weight portions, Chinese yam 30 weight portion ~ 40 weight portions, birthwort 15 weight portion ~ 25 weight portions, fructus choerospondiatis 10 weight portion ~ 20 weight portions, the fruit of glossy privet 45 weight portion ~ 55 weight portions, the tuber of stemona 10 weight portion ~ 20 weight portions and Radix Glycyrrhizae 20 weight portion ~ 30 weight portions.
In described Chinese herbal feed additive, the weight portion of each bulk drug is further preferably respectively: sealwort 58 weight portion ~ 62 weight portions, reticulate millettia 28 weight portion ~ 32 weight portions, the Radix Astragali 88 weight portion ~ 92 weight portions, caulis lonicerae 23 weight portion ~ 27 weight portions, hawthorn 18 weight portion ~ 22 weight portions, corydalis tuber 28 weight portion ~ 32 weight portions, Herba Andrographitis 23 weight portion ~ 27 weight portions, west safflower 33 weight portion ~ 37 weight portions, the root of herbaceous peony 28 weight portion ~ 32 weight portions, the stem of noble dendrobium 43 weight portion ~ 47 weight portions, motherwort 28 weight portion ~ 32 weight portions, Psoralea corylifolia 48 weight portion ~ 52 weight portions, giant knotweed 38 weight portion ~ 42 weight portions, golden cypress 58 weight portion ~ 62 weight portions, Poria cocos 23 weight portion ~ 27 weight portions, Ligusticum wallichii 28 weight portion ~ 32 weight portions, Chinese yam 33 weight portion ~ 37 weight portions, birthwort 18 weight portion ~ 22 weight portions, fructus choerospondiatis 13 weight portion ~ 17 weight portions, the fruit of glossy privet 48 weight portion ~ 52 weight portions, the tuber of stemona 13 weight portion ~ 17 weight portions and Radix Glycyrrhizae 23 weight portion ~ 27 weight portions.
In described Chinese herbal feed additive, the weight portion of each bulk drug is most preferably respectively: sealwort 60 weight portions, reticulate millettia 30 weight portions, the Radix Astragali 90 weight portions, caulis lonicerae 25 weight portions, hawthorn 20 weight portions, corydalis tuber 30 weight portions, Herba Andrographitis 25 weight portions, west safflower 35 weight portions, the root of herbaceous peony 30 weight portions, the stem of noble dendrobium 45 weight portions, motherwort 30 weight portions, Psoralea corylifolia 50 weight portions, giant knotweed 40 weight portions, golden cypress 60 weight portions, Poria cocos 25 weight portions, Ligusticum wallichii 30 weight portions, Chinese yam 35 weight portions, birthwort 20 weight portions, fructus choerospondiatis 15 weight portions, the fruit of glossy privet 50 weight portions, the tuber of stemona 15 weight portions and Radix Glycyrrhizae 25 weight portions.
The present invention also provides a kind of feed, and it comprises: silage corn, dregs of beans, wheat bran, above-mentioned Chinese herbal feed additive.
In described feed, the weight portion of each composition is respectively: the weight portion of silage corn is 55 weight portion ~ 65 weight portions, weight portion 13 weight portion ~ 23 weight portions of dregs of beans, the weight portion of wheat bran is 20 weight portion ~ 30 weight portions, and the weight portion of above-mentioned Chinese herbal feed additive is 10 weight portion ~ 16 weight portions.
In described feed, the weight portion of each composition is preferably respectively: the weight portion of silage corn is 60 weight portions, weight portion 18 weight portions of dregs of beans, and the weight portion of wheat bran is 25 weight portions, the weight portion of above-mentioned Chinese herbal feed additive is 13 weight portions.
In described feed, can also add antioxidant, the weight portion of described antioxidant in described feed is 2 weight portion ~ 4 weight portions, more preferably 3 weight portions.
Described antioxidant comprises vitamin E (V e) and beta carotene in one or both mixing, vitamin E is a kind of fat-soluble antioxidant of important opposing peroxidatic reaction of lipid free radical, at immunology, be mainly to strengthen neutrophil cell function, beta carotene is not only vitamin A (V in vivo a) source, also there is antioxidant and reduce the effect that phagocyte endoperoxide forms, the weight ratio of vitamin E and beta carotene is preferably 1:1.
In described feed, sea can add selenium methionine, and the weight portion of described selenium methionine in described feed is 0.5 weight portion ~ 1 weight portion, more preferably 0.8 weight portion.
It is glutathione peroxidase (GP to the acting body of the trace element selenium that selenium methionine provides in antioxidant system now x) essential constituent, GP xdestroying hydrogen peroxide and lipid hydroperoxide in vivo, Cell protection film is avoided the broken evil of peroxide, with superoxide dismutase (SOD), catalase and V ein maintaining tissue, low concentration of peroxide plays an important role.
In described feed, can also add the conventional additives such as vitamin premix, amino acid premix.
Preferably, described feed only consists of mentioned component.
The present invention also provides the preparation method of above-mentioned feed, is specially:
The first step, mixes each bulk drug in above-mentioned Chinese herbal feed additive in proportion, sends in mixer and stirs 20 minutes ~ 30 minutes, add with respect to 5 ~ 8 times of water of bulk drug quality sum, decoct 2 ~ 4 hours, decoction liquor is filtered, filter residue adds again with respect to 2 ~ 4 times of water of bulk drug quality sum, again decocts 2 ~ 4 hours, and decoction liquor is filtered, filtered fluid is merged, heating is concentrated to be obtained and gets dry extract except anhydrating, and is ground into powder, dry, obtain Chinese herbal feed additive powder;
Second step, silage corn, dregs of beans, wheat bran are sent into stirrer for mixing in proportion, the dry Chinese herbal feed additive powder that adds the first step to obtain, send into the steam modulation 6~7 minutes that passes into 90~100 ℃ in modem, making the moisture after modulation is 12%~14%, then at the temperature of 95~100 ℃, enters extrusion granulator and granulates;
The 3rd step, the pellet after granulating is cooling, packing.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese herbal feed additive 1
By sealwort 60g, reticulate millettia 30g, Radix Astragali 90g, caulis lonicerae 25g, hawthorn 20g, corydalis tuber 30g, Herba Andrographitis 25g, west safflower 35g, root of herbaceous peony 30g, stem of noble dendrobium 45g, motherwort 30g, Psoralea corylifolia 50g, giant knotweed 40g, golden cypress 60g, Poria cocos 25g, Ligusticum wallichii 30g, Chinese yam 35g, birthwort 20g, fructus choerospondiatis 15g, fruit of glossy privet 50g, tuber of stemona 15g and Radix Glycyrrhizae 25g mix, send in mixer and stir 30 minutes, add phase 4.8kg water, decoct 4 hours, decoction liquor is filtered, filter residue adds the water with respect to bulk drug quality sum 2.5kg again, again decoct 4 hours, decoction liquor is filtered, filtered fluid is merged, heating is concentrated except anhydrating, obtain and get dry extract, be ground into powder, dry, obtain Chinese herbal feed additive 1.
Embodiment 2 Chinese herbal feed additives 2
By sealwort 55g, reticulate millettia 25g, Radix Astragali 85g, caulis lonicerae 20g, hawthorn 15g, corydalis tuber 25g, Herba Andrographitis 20g, west safflower 30g, root of herbaceous peony 25g, stem of noble dendrobium 40g, motherwort 25g, Psoralea corylifolia 45g, giant knotweed 35g, golden cypress 55g, Poria cocos 20g, Ligusticum wallichii 25g, Chinese yam 30g, birthwort 15g, fructus choerospondiatis 10g, fruit of glossy privet 45g, tuber of stemona 10g and Radix Glycyrrhizae 20g mix, send in mixer and stir 30 minutes, add phase 4kg water, decoct 4 hours, decoction liquor is filtered, filter residue adds the water with respect to bulk drug quality sum 2kg again, again decoct 4 hours, decoction liquor is filtered, filtered fluid is merged, heating is concentrated except anhydrating, obtain and get dry extract, be ground into powder, dry, obtain Chinese herbal feed additive 2.
Embodiment 3 Chinese herbal feed additives 3
By sealwort 65g, reticulate millettia 35g, Radix Astragali 95g, caulis lonicerae 30g, hawthorn 25g, corydalis tuber 35g, Herba Andrographitis 30g, west safflower 40g, root of herbaceous peony 35g, stem of noble dendrobium 50g, motherwort 35g, Psoralea corylifolia 55g, giant knotweed 45g, golden cypress 65g, Poria cocos 30g, Ligusticum wallichii 35g, Chinese yam 40g, birthwort 25g, fructus choerospondiatis 20g, fruit of glossy privet 55g, tuber of stemona 20g and Radix Glycyrrhizae 30g mix, send in mixer and stir 30 minutes, add phase 5.5kg water, decoct 4 hours, decoction liquor is filtered, filter residue adds the water with respect to bulk drug quality sum 3kg again, again decoct 4 hours, decoction liquor is filtered, filtered fluid is merged, heating is concentrated except anhydrating, obtain and get dry extract, be ground into powder, dry, obtain Chinese herbal feed additive 3.
Embodiment 4 feeds 1
By silage corn 6kg; dregs of beans 1.8kg; wheat bran 2.5kg sends into stirrer for mixing; Chinese herbal feed additive 1 powder that adds 1.3kg embodiment 1 preparation; send into the steam modulation 7 minutes that passes into 95 ℃ in modem, making the moisture after modulation is 12%, then at the temperature of 95 ℃, enters extrusion granulator and granulates; pellet after granulating is cooling, packing.
Embodiment 5 feeds 2
By silage corn 5.5kg; dregs of beans 1.3kg; wheat bran 2.0kg, 100g vitamin E and 100g beta carotene, 50g selenium methionine is sent into stirrer for mixing; Chinese herbal feed additive 2 powder that add 1kg embodiment 2 preparations; send into the steam modulation 7 minutes that passes into 95 ℃ in modem, making the moisture after modulation is 12%, then at the temperature of 95 ℃, enters extrusion granulator and granulates; pellet after granulating is cooling, packing.
Embodiment 6 feeds 3
By silage corn 6.5kg; dregs of beans 2.3kg; wheat bran 3.0kg, 200g vitamin E and 200g beta carotene, 50g selenium methionine is sent into stirrer for mixing; Chinese herbal feed additive 3 powder that add 1.6kg embodiment 3 preparations; send into the steam modulation 7 minutes that passes into 95 ℃ in modem, making the moisture after modulation is 12%, then at the temperature of 95 ℃, enters extrusion granulator and granulates; pellet after granulating is cooling, packing.
Embodiment 7 animal feeding examples
Animal used as test and grouping
Perinatal period, holstein cow was 80,4~6 years old age, parity 3~5 tires, and Xuan Yu Shandong Province cultivation factory, clinical examination is healthy, and age-based, parity, the expected date of childbirth, close principle was divided into Chinese drug-treated group, control group, 40 every group.
Feeding and management
The test equal holddown groove of milk cow position, difference 5: 00 in the morning, 12: 00 noons and evening 18: 00, filling was fed, control group feeding basal feed, its composition is silage corn 6kg, dregs of beans 1.8kg, wheat bran 2.5kg, from 1 month expected date of childbirth, started to calculate, observe two months, treatment group started the feed of the feeding embodiment of the present invention 4 preparations from 15 days expected dates of childbirth, feeding is 30 days continuously, also be to start to calculate from 1 month expected date of childbirth, observe two months, in whole breeding observing process, do not use antibiotic, the strict feeding environment of controlling cattle farm, process in time discarded object.
Main agents
Liquaemin, biochemical-pharmaceutical factory, Jinan City.Ox IL-2, IFN-γ, TNF-α EL ISA kit, U.S. Adlit teram Diagnostic Laboratories produces.
Key instrument equipment
318 type ELIASAs, Shanghai Sanke Instrument Co., Ltd.The desk-top constant temperature culture oscillator of ZHWY-103B type, Shanghai ZHICHENG Anaiytical Instrument Manufacturing Co., Ltd..
Detect index
Two groups all 15 days expected dates of childbirth, 0 day postpartum and noon 15 day postpartum milk cow on an empty stomach, jugular vein is taked 10 mL heparin anti-coagulatings, by EL ISA kit description, measures respectively the content of plasma IL-2, IFN-γ, TNF-α.
Statistical method
Utilize SPSS13. 0 statistical software to analyze, data represent by mean+SD.
Result
The testing result of milk cow plasma IL-2, in Table 1.
The testing result (ng/mL) of table 1 milk cow plasma IL-2
Figure 2013101119193100002DEST_PATH_IMAGE001
IL-2 has panimmunity function, is the key link that ensures the normal immunologic function of body, is the network center of Organism immunoregulation.IL-2 can strengthen mammary gland monocyte hyperplasia, strengthens lymphocyte toxic action and sterilizing function and thick liquid cell quantity.IL-2 can be by promoting clone's property of a certain specific T cell colony to increase, induction NK cell and LAK cell produce the cell factors such as IFN-γ, TNF-α, activated macrophage, improve the immunologic function that Th cell number and function strengthen body, the minimizing of endogenous IL-2 can cause that immunologic function declines, then diseases induced.From found that of table 1, the milk cow Chinese medicine composition of the present invention of antenatal and postpartum feeding, can significantly improve milk cow plasma IL-2 content, and P<0.05, strengthens Diseases of Cow immunity of organism level, improves the premunition of body.
The testing result of milk cow blood plasma IFN-γ, in Table 2.
The testing result (pg/ mL) of table 2 milk cow blood plasma IFN-γ
Figure 407437DEST_PATH_IMAGE002
IFN-γ is secreted main effects molecule after N K cell, T cell and N KT cell activation, energy activated mononuclear macrophage, IFN-γ has very strong immunoregulation effect, it can regulate the immunologic function of T, bone-marrow-derived lymphocyte, the activity of antiproliferative activity aspect is stronger, and antiviral activity slightly a little less than.It has been generally acknowledged that, IFN-γ is the positive modulators of immune response, can not only raise immune response by number of mechanisms, and the cell of energy direct killing tumour cell and virus infections.Diseases of Cow is antenatal to be fed after Chinese medicine composition of the present invention, has significantly improved milk cow blood plasma IFN-γ content, and P<0.05, has strengthened Diseases of Cow body disease-resistant power.
The impact of Chinese medicine composition of the present invention on milk cow Plasma TNF-α, the results are shown in Table 3.
Table 3 Chinese medicine composition of the present invention is on the impact of milk cow Plasma TNF-α (pg/ mL)
Figure 996681DEST_PATH_IMAGE003
TNF-α is a kind of monokine, mainly by monocyte and macrophage, is produced, and has many-sided BA, as direct killing or inhibitory action; Improve the phagocytic activity of neutrophil cell, increase superoxide anion and produce; There is anti-infectious function, suppress virus replication, suppress that virus protein is synthetic, the generation of virion and infectious TNF-α promote cell proliferation and differentiation, strengthen thymocyte, T lymphopoiesis ability that IL-2 relies on, promote the lymphokines such as IL-2, IFN-γ to produce, and IFN-γ have obvious humidification to the biological action of TNF.The demonstration of table 3 result, cow in perinatal period is fed after Chinese medicine composition of the present invention, can obviously improve Diseases of Cow Plasma TNF-alpha content, P<0.05.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (9)

1. a Chinese herbal feed additive that improves the immunologic function of cow in perinatal period, is characterized in that: the bulk drug of described Chinese herbal feed additive comprises sealwort, reticulate millettia, the Radix Astragali, caulis lonicerae, hawthorn, corydalis tuber, Herba Andrographitis, west safflower, the root of herbaceous peony, the stem of noble dendrobium, motherwort, Psoralea corylifolia, giant knotweed, golden cypress, Poria cocos, Ligusticum wallichii, Chinese yam, birthwort, fructus choerospondiatis, the fruit of glossy privet, the tuber of stemona and Radix Glycyrrhizae;
In described Chinese herbal feed additive, the weight portion of each bulk drug is respectively: sealwort 55 weight portion ~ 65 weight portions, reticulate millettia 25 weight portion ~ 35 weight portions, the Radix Astragali 85 weight portion ~ 95 weight portions, caulis lonicerae 20 weight portion ~ 30 weight portions, hawthorn 15 weight portion ~ 25 weight portions, corydalis tuber 25 weight portion ~ 35 weight portions, Herba Andrographitis 20 weight portion ~ 30 weight portions, west safflower 30 weight portion ~ 40 weight portions, the root of herbaceous peony 25 weight portion ~ 35 weight portions, the stem of noble dendrobium 40 weight portion ~ 50 weight portions, motherwort 25 weight portion ~ 35 weight portions, Psoralea corylifolia 45 weight portion ~ 55 weight portions, giant knotweed 35 weight portion ~ 45 weight portions, golden cypress 55 weight portion ~ 65 weight portions, Poria cocos 20 weight portion ~ 30 weight portions, Ligusticum wallichii 25 weight portion ~ 35 weight portions, Chinese yam 30 weight portion ~ 40 weight portions, birthwort 15 weight portion ~ 25 weight portions, fructus choerospondiatis 10 weight portion ~ 20 weight portions, the fruit of glossy privet 45 weight portion ~ 55 weight portions, the tuber of stemona 10 weight portion ~ 20 weight portions and Radix Glycyrrhizae 20 weight portion ~ 30 weight portions.
2. Chinese herbal feed additive as claimed in claim 1, it is characterized in that: in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively: sealwort 60 weight portions, reticulate millettia 30 weight portions, the Radix Astragali 90 weight portions, caulis lonicerae 25 weight portions, hawthorn 20 weight portions, corydalis tuber 30 weight portions, Herba Andrographitis 25 weight portions, west safflower 35 weight portions, the root of herbaceous peony 30 weight portions, the stem of noble dendrobium 45 weight portions, motherwort 30 weight portions, Psoralea corylifolia 50 weight portions, giant knotweed 40 weight portions, golden cypress 60 weight portions, Poria cocos 25 weight portions, Ligusticum wallichii 30 weight portions, Chinese yam 35 weight portions, birthwort 20 weight portions, fructus choerospondiatis 15 weight portions, the fruit of glossy privet 50 weight portions, the tuber of stemona 15 weight portions and Radix Glycyrrhizae 25 weight portions.
3. the preparation method of Chinese herbal feed additive described in claim 1, it is characterized in that: described preparation method's step is specially, each bulk drug in above-mentioned Chinese herbal feed additive is mixed in proportion, send in mixer and stir 20 minutes ~ 30 minutes, add with respect to 5 ~ 8 times of water of bulk drug quality sum, decoct 2 ~ 4 hours, decoction liquor is filtered, filter residue adds again with respect to 2 ~ 4 times of water of bulk drug quality sum, again decoct 2 ~ 4 hours, decoction liquor is filtered, filtered fluid is merged, heating is concentrated except anhydrating, obtain and get dry extract, be ground into powder, dry, obtain Chinese herbal feed additive powder.
4. a feed, is characterized in that, comprising: the Chinese herbal feed additive described in silage corn, dregs of beans, wheat bran and claim 1 or 2.
5. feed as claimed in claim 4, it is characterized in that: in described feed, to be respectively the weight portion of silage corn be 55 weight portion ~ 65 weight portions to the weight portion of each composition, weight portion 13 weight portion ~ 23 weight portions of dregs of beans, the weight portion of wheat bran is 20 weight portion ~ 30 weight portions, and the weight portion of Chinese herbal feed additive is 10 weight portion ~ 16 weight portions.
6. feed as claimed in claim 4, is characterized in that: in described feed, can also add antioxidant, the weight portion of described antioxidant in described feed is 2 weight portion ~ 4 weight portions.
7. feed as claimed in claim 6, is characterized in that: described antioxidant is vitamin E (V e) and beta carotene in one or both mixing.
8. feed as claimed in claim 4, is characterized in that: in described feed, can also add selenium methionine, the weight portion of described selenium methionine in described feed is 0.5 weight portion ~ 1 weight portion.
9. the preparation method of feed described in claim 4, is characterized in that: described preparation method's concrete steps are,
The first step, prepares Chinese herbal feed additive powder in accordance with the method for claim 3;
Second step, silage corn, dregs of beans, wheat bran are sent into stirrer for mixing in proportion, the dry Chinese herbal feed additive powder that adds the first step to obtain, send into the steam modulation 6~7 minutes that passes into 90~100 ℃ in modem, making the moisture after modulation is 12%~14%, then at the temperature of 95~100 ℃, enters extrusion granulator and granulates;
The 3rd step, the pellet after granulating is cooling, packing.
CN201310111919.3A 2013-04-02 2013-04-02 Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period Active CN103141705B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310111919.3A CN103141705B (en) 2013-04-02 2013-04-02 Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310111919.3A CN103141705B (en) 2013-04-02 2013-04-02 Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period

Publications (2)

Publication Number Publication Date
CN103141705A CN103141705A (en) 2013-06-12
CN103141705B true CN103141705B (en) 2014-04-09

Family

ID=48540264

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310111919.3A Active CN103141705B (en) 2013-04-02 2013-04-02 Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period

Country Status (1)

Country Link
CN (1) CN103141705B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103392925B (en) * 2013-07-11 2014-04-16 曾勇 Concentrate supplement special for dairy cow in perinatal period
CN103689269B (en) * 2013-12-11 2015-06-17 徐茂航 Milk cow forage
CN104171366B (en) * 2014-06-30 2017-02-15 安徽省农业科学院畜牧兽医研究所 Feed additive for improving metabolism of dairy cows during perinatal period and production method thereof
CN104522314B (en) * 2014-12-05 2017-06-16 安徽科技学院 A kind of poultry piece scattered, preparation method and application of three leaves
CN104782936A (en) * 2015-03-27 2015-07-22 兰梅 Milk cow feed
CN105533184A (en) * 2016-01-07 2016-05-04 山东新希望六和集团有限公司 Cow feed additive for improving cow milk quality and preparation method thereof
CN106173292A (en) * 2016-07-07 2016-12-07 广西山水牛农业有限责任公司 One cow feedstuff age of sucking and production technology thereof
CN106615729A (en) * 2016-11-16 2017-05-10 广西山水牛农业有限责任公司 Special feed for cows in gestation period
CN107535674A (en) * 2017-09-27 2018-01-05 贵州梵净山农业高科技股份有限公司 A kind of milk cow is special to increase milk feed addictive and preparation method thereof
CN111480735A (en) * 2020-04-07 2020-08-04 安徽广通生物科技有限责任公司 Concentrate supplement for relieving immune suppression of beef cattle and improving immunity and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101061832A (en) * 2006-04-27 2007-10-31 韩凌云 Premix feed specially for high yield cow in perinatal period and the method of producing the same
CN102246909A (en) * 2010-06-21 2011-11-23 北京科兴大地饲料有限公司 Special healthcare feed for perinatal milk cows and preparing method thereof
CN102783564A (en) * 2012-08-01 2012-11-21 六安亿牛乳业有限公司 Application method for Chinese herbal medicine during perinatal period of dairy cow
CN102823779A (en) * 2012-09-27 2012-12-19 山东新希望六和集团有限公司 Dairy cow feed, preparation method and Chinese medicine for improving dairy cow production performance

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101061832A (en) * 2006-04-27 2007-10-31 韩凌云 Premix feed specially for high yield cow in perinatal period and the method of producing the same
CN102246909A (en) * 2010-06-21 2011-11-23 北京科兴大地饲料有限公司 Special healthcare feed for perinatal milk cows and preparing method thereof
CN102783564A (en) * 2012-08-01 2012-11-21 六安亿牛乳业有限公司 Application method for Chinese herbal medicine during perinatal period of dairy cow
CN102823779A (en) * 2012-09-27 2012-12-19 山东新希望六和集团有限公司 Dairy cow feed, preparation method and Chinese medicine for improving dairy cow production performance

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
中草药在家畜饲料添加剂的应用;郭忠华;《养殖技术顾问》;20101031(第10期);第175页 *
中草药添加剂在奶牛上的研究进展;刘瑞生;《乳业科学与技术》;20061231(第6期);第293-294页 *
刘瑞生.中草药添加剂在奶牛上的研究进展.《乳业科学与技术》.2006,(第6期),第293-294页.
奶牛中草药饲料添加剂的应用研究;胡美华;《兽药与饲料添加剂》;20021031;第7卷(第5期);第31-33页 *
胡美华.奶牛中草药饲料添加剂的应用研究.《兽药与饲料添加剂》.2002,第7卷(第5期),第31-33页.
郭忠华.中草药在家畜饲料添加剂的应用.《养殖技术顾问》.2010,(第10期),第175页.

Also Published As

Publication number Publication date
CN103141705A (en) 2013-06-12

Similar Documents

Publication Publication Date Title
CN103141705B (en) Traditional Chinese medicine feed additive for improving immunological competence of dairy cattle in perinatal period
CN103829092B (en) Traditional Chinese medicinal composition and feed for treating escherichia coli diarrhea of piglets
CN102940155B (en) Duckling feed for cherry valley duck and preparation method thereof
CN105265806A (en) Beef cattle special feed additive and preparation method thereof
CN103385392A (en) Novel laying hen feed
CN108338258A (en) A kind of farrowing sow Synbiotic feed additive and preparation method and application
CN108208378A (en) A kind of sow feed additive for preventing piglet yellow-white dysentery
CN103141704B (en) Traditional Chinese medicine feed for treating swine plague
CN109260443A (en) A kind of pharmaceutical composition for treating malignant tumour
CN105233099A (en) Traditional Chinese medicine composition capable of increasing milk yield of cows and preparation method thereof
CN104544169A (en) Pork-skin jelly capable of promoting milk secretion and preparation method of pork-skin jelly
CN104304809A (en) Feed additive for cow during lactation period and application of feed additive
CN107998366A (en) It is a kind of suitable for Chinese medicine composition of puerpera&#39;s lactagogue at initial stage in postpartum and preparation method thereof
CN103960542A (en) Feed and traditional Chinese medicine composition for preventing and treating swine eperythrozoonosis
CN103142943B (en) Traditional Chinese medicine composite with immune function and used for treating mastitis of cows
CN103222565B (en) Traditional chinese medicine milk increasing agent
CN103735710B (en) Traditional Chinese medicine composition for treating recessive mastitis of dairy cows and preparation method thereof
CN104082529B (en) For preventing and treating the feed of piglet yellow-white dysentery
CN108210779A (en) Tranquilizing the mind centering soup
CN106344722A (en) Acute suppurative mastitis and treatment medicine thereof
CN104771585A (en) Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof
CN103585437B (en) Pure Chinese medicine composition for the treatment of cow endometritis and preparation method thereof
CN108420860A (en) A kind of Chinese medicine composition of gynemetrics pregnant woman postpartum promoting lactation
CN107960535A (en) A kind of feed addictive and its production method for preventing beef cattle gastroenteritis
CN106377659A (en) Traditional Chinese medicine pulvis used for preventing and treating fever diseases of livestock and poultry

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20211206

Address after: 610000 No. 1188, Baicao Road, West Park, hi tech Zone, Chengdu, Sichuan

Patentee after: CHENGDU CENTURY INVESTMENT Co.,Ltd.

Address before: 266061 Qingdao Industrial Park, Ji Hong Tan Street, Chengyang District, Qingdao, Shandong.

Patentee before: SHANDONG NEW HOPE LIUHE GROUP Co.,Ltd.