CN103110806A - Medicine for treating climacteric syndrome - Google Patents
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Abstract
本发明涉及一种治疗更年期综合症的药物。该药物由下述重量份的原料药制成：生熟地10～30份、山萸肉6～12份、何首乌100份、山药15～30份、丹皮0.2份、白芍5份、茯苓15份、五味子1.5～6份、寸冬10～15份、远志3～9份、大云1～3份。临床发现本发明是治疗更年期综合症的药物，服用一个疗程就可以明显改变更年期妇女的一些临床症状，如月经紊乱、面色潮红、心悸、失眠、乏力、抑郁、多虑、情绪不稳定，易激动，注意力难于集中等。帮助更年期妇女顺利安全度过人生这一转折点。The invention relates to a medicine for treating menopausal syndrome. The medicine is prepared from the following raw materials by weight: 10-30 parts of raw and cooked rehmannia, 6-12 parts of cornus, 100 parts of Polygonum multiflorum, 15-30 parts of Chinese yam, 0.2 part of paeonol, 5 parts of white peony root, 15 parts of Poria cocos 1.5-6 parts of Schisandra, 10-15 parts of Cundong, 3-9 parts of Polygala, and 1-3 parts of Dayun. It is clinically found that the present invention is a medicine for treating menopausal syndrome, and some clinical symptoms of menopausal women can be obviously changed after taking a course of treatment, such as menstrual disorder, flushing, heart palpitations, insomnia, fatigue, depression, worry, emotional instability, and irritability , Difficulty concentrating, etc. Help menopausal women pass through this turning point in life smoothly and safely.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of climacteric syndrome.
Background technology
Climacteric syndrome is the series of symptoms that is caused by decrease in estrogen.Climacteric women, due to hypo-ovaria, hyperpituitarism, the promoting sexual gland hormone of supersecretion causes the autonomic nervous dysfunction, thereby the different symptom of a series of degree occurs, as menstruation variation, flushed face, cardiopalmus, insomnia, weak, depressed, worry too much, emotional instability, emotional, attention is difficult to concentrate etc., is called " climacteric syndrome." most of women are because hypo-ovaria is slower, body self-regulation and compensatoryly be enough to adapt to this variation, or light symptoms is only arranged.The traditional Chinese medical science thinks that climacteric syndrome is deficiency of kidney-QI, and menses declines few, so that imbalance between YIN and YANG causes.Therefore when treatment, take the kidney invigorating gas, regulating YIN and YANG as main method.
Summary of the invention
The medicine for the treatment of climacteric syndrome provided by the invention is characterized in that: this medicine is made by the crude drug of following weight parts: give birth to 10～30 parts, Radix Rehmanniae Preparata, 6～12 parts of Fructus Corni, 100 parts of Radix Polygoni Multiflori, 15～30 parts of Rhizoma Dioscoreaes, 0.2 part of Cortex Moutan, 5 parts of the Radix Paeoniae Albas, 15 parts, Poria, 1.5～6 parts of Fructus Schisandrae Chinensis, 10～15 parts of Radix Ophiopogonis, 3～9 parts of Radix Polygalaes, 1～3 part of Herba Cistanches.
The present invention gives a kind of medicine of preferred treatment climacteric syndrome, it is characterized in that: this medicine is made by the crude drug of following weight parts: give birth to 20 parts, Radix Rehmanniae Preparata, 12 parts of Fructus Corni, 100 parts of Radix Polygoni Multiflori, 25 parts of Rhizoma Dioscoreaes, 0.2 part of Cortex Moutan, 5 parts of the Radix Paeoniae Albas, 15 parts, Poria, 5 parts of Fructus Schisandrae Chinensis, 15 parts of Radix Ophiopogonis, 9 parts of Radix Polygalaes, 3 parts of Herba Cistanches.
The medicine of described treatment climacteric syndrome is endured 2 times with marmite by described crude drug, and the water that adds for the first time is advisable to exceed 3 centimeters of medicines, and two fry in shallow oil to add water to and flood powder for well, endures to get final product in 30 minutes at every turn.
Each crude drug pharmacodynamic analysis of the medicine for the treatment of climacteric syndrome provided by the invention is as follows:
Give birth to Radix Rehmanniae Preparata (rehmaniaglutinosalibosch): YIN nourishing, enrich blood, strong, heart tonifying, diuresis, blood sugar lowering, antiallergic, removing heat from blood, heat clearing away is relievingd asthma.Be used for the treatment of blood deficiency, anemia, stasis, the deficiency of YIN, chronic deficient, weak asthenia of essence and blood, weakness, soreness of the waist and knees, dry mouth is thirsty, thready and rapid pulse, deficiency of YIN chronic nephritis, hypertension.
Fructus Corni (asiatic cornelian cherry fruit): sour, puckery, tepor.Return liver, kidney channel.Be used for the treatment of liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping and only collapse hidroschesis and also have in addition promoting the production of body fluid to quench thirst.Be used for soreness of waist and knee joint dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses menoxenia, profuse sweating collapse.Interior-heat is quenched one's thirst.
Radix Polygoni Multiflori (fleeceflower root): promote hemopoietic, immunity, blood fat reducing and atherosclerosis, protect the liver, slow down aging, loosening bowel to relieve constipation, make hepatic glycogen obviously increase function.Be used for the treatment of the blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; The dryness of the intestine constipation; The chronic malaria body is empty; The rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid.
Rhizoma Dioscoreae (Dioscorea opposita): sweet in the mouth, property is flat.Return spleen, lung, kidney channel.Be used for the treatment of the spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.
Cortex Moutan (Cortex Moutan Radicis): cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.Bitter in the mouth, suffering are slightly cold.GUIXIN, liver, kidney channel.Be used for the treatment of clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; The rheumatism pyretic arthralgia.
The Radix Paeoniae Alba (White Paeony Root): picric acid is cool.Enter liver, spleen channel.Be used for nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Poria (Indian bread): sweet, light, flat.The diuretic medicine; Diuretics with the action of eliminating dampness.
Fructus Schisandrae Chinensis (Chinese magnoliavine fruit): astringe the lung, nourishing kidney is promoted the production of body fluid, and receives antiperspirant, arresting seminal emission.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough: few thirsty, the dry cough spitting of blood in Tianjin that is used for lung-stomach yin deficiency; The cards such as the palpitation and being susceptible to fright of insufficiency of heart-YIN and calentura later stage consumption of body fluid by heat.
Radix Polygalae (milkwort root): bitter, hot, tepor.GUIXIN, kidney, lung meridian.The Fructus Alpiniae Oxyphyllae of calming the nerves is eliminated the phlegm, detumescence.Be used for the treatment of the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Herba Cistanches (Desertliving Cistanche): reinforcing the kidney and supporting YANG, loosening bowel to relieve constipation, hard masses softening and resolving.Be used for the treatment of menoxenia, amenorrhea, infertile, sexual impotence, seminal emission, dribbling urination, hoarseness and aphonia, constipation, deficiency and coldness is had loose bowels, lump in the abdomen.
Beneficial effect of the present invention is: the medicine of clinical discovery treatment climacteric syndrome of the present invention, take and just can obviously change some clinical symptoms of climacteric women a course for the treatment of, as menoxenia, flushed face, cardiopalmus, insomnia, weak, depressed, worry too much, emotional instability, emotional, attention is difficult to concentrate etc.Help the smooth degree of safety of climacteric women to cross this turning point of life.
The specific embodiment
The following examples can make those skilled in the art more fully understand the present invention, but do not limit the present invention in any way.
Embodiment 1
A kind of medicine for the treatment of climacteric syndrome, this medicine is made (every dose of Chinese medicine) by following raw material medicaments: give birth to Radix Rehmanniae Preparata 20g, Fructus Corni 12g, Radix Polygoni Multiflori 100g, Rhizoma Dioscoreae 25g, Cortex Moutan 0.2g, Radix Paeoniae Alba 5g, Poria 15g, Fructus Schisandrae Chinensis 5g, Radix Ophiopogonis 15g, Radix Polygalae 9g, Herba Cistanches 3g.Each raw material is available from pharmacy.
The medicine of described treatment climacteric syndrome is endured 2 times with marmite by described crude drug, and the water that adds for the first time is advisable to exceed 3 centimeters of medicines, and two fry in shallow oil to add water to and flood powder for well, endures to get final product in 30 minutes at every turn.Then the medicinal liquid of enduring for 2 times is drinking mixed, 2 times/days, 1 dose/1 day, serve on 7～10 days.
Test of pesticide effectiveness summary:
One, case is selected
691 routine cases all come from the 1～December department of Chinese medicine out-patient in 2012 of Affiliated Hospital of Yanan University.Be divided into treatment group and each 691 examples of matched group by the table of random number method.Treatment group: 35～60 years old age, average (47.5 ± 9.1) year; Disease time 2～10 months, average (6.1 ± 3.7) individual month; The symptom scores standard: with reference to " clinical gynecology " " Jern24 class menopause syndrome ", every class by light, in, 1,2,3 minute heavily respectively, accumulative total 72 minutes.Matched group: 37～55 years old age, average (46.2 ± 4.7) year; Disease time 1～9 month, average (4.3 ± 3.5) individual month; Jern24 class Symptoms Self-assessment divides (47.3 ± 6.2) to divide.
Two, administrated method
Described crude drug is endured 2 times with marmite, and the water that adds for the first time is advisable to exceed 3 centimeters of medicines, and two fry in shallow oil to add water to and flood powder for well, endures to get final product in 30 minutes at every turn.Then the medicinal liquid of enduring for 2 times is drinking mixed, 2 times/days, 1 dose/1 day, 7～10 days was a course for the treatment of.
The criterion of curative effect: the criterion of curative effect is cured: warm the transference cures such as sweating, cardiopalmus, abnormal emotion-thought, insomnia with reference to " clinical disease diagnosis is according to curing the improvement standard " and " traditional Chinese medical science disease Standardization of diagnosis and curative effect "; Take a turn for the better: all diseases alleviate; Do not heal: all diseases are unchanged.By Jern24 class symptom score (total points 72 minutes): total points≤9 are divided into healing; Total points 10～40 minutes also descends more than 20% as taking a turn for the better before treatment; Total points＞40 minute or be declined by less than 20% for not healing before treatment.
Three, efficacy result analysis
1, cure: 601 examples, effective percentage 86.97%;
2, effective: 672 examples, 97.25%;
3, do not heal: 19 examples, 2.75%.
The above; only for the better specific embodiment of the present invention, but protection scope of the present invention is not limited to this, anyly is familiar with those skilled in the art in the technical scope that the present invention discloses; the variation that can expect easily or replacement are within all should being encompassed in protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of claim.
Claims (3)
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| CN2013100313069A CN103110806A (en) | 2013-01-17 | 2013-01-17 | Medicine for treating climacteric syndrome |
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| CN2013100313069A CN103110806A (en) | 2013-01-17 | 2013-01-17 | Medicine for treating climacteric syndrome |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825932A (en) * | 2015-05-20 | 2015-08-12 | 南京华宽信息咨询中心 | Traditional Chinese medicine for treating insomnia |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1586563A (en) * | 2004-07-07 | 2005-03-02 | 香港养春堂中药有限公司 | Female climacteric health-care pill |
| CN101721624A (en) * | 2008-10-13 | 2010-06-09 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Traditional Chinese medicine composition for treating menopausal syndrome and prepration method thereof |
| CN102698104A (en) * | 2012-06-06 | 2012-10-03 | 张俊波 | Medicine for treating climacteric syndrome and preparation method |
-
2013
- 2013-01-17 CN CN2013100313069A patent/CN103110806A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1586563A (en) * | 2004-07-07 | 2005-03-02 | 香港养春堂中药有限公司 | Female climacteric health-care pill |
| CN101721624A (en) * | 2008-10-13 | 2010-06-09 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Traditional Chinese medicine composition for treating menopausal syndrome and prepration method thereof |
| CN102698104A (en) * | 2012-06-06 | 2012-10-03 | 张俊波 | Medicine for treating climacteric syndrome and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 何桂英: "女性更年期综合征的治疗", 《福建中医学院学报》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825932A (en) * | 2015-05-20 | 2015-08-12 | 南京华宽信息咨询中心 | Traditional Chinese medicine for treating insomnia |
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Application publication date: 20130522 |