CN103100066A - Traditional Chinese medicine composition for tranquilizing and allaying excitement and preparation method thereof - Google Patents
Traditional Chinese medicine composition for tranquilizing and allaying excitement and preparation method thereof Download PDFInfo
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- CN103100066A CN103100066A CN2012105475578A CN201210547557A CN103100066A CN 103100066 A CN103100066 A CN 103100066A CN 2012105475578 A CN2012105475578 A CN 2012105475578A CN 201210547557 A CN201210547557 A CN 201210547557A CN 103100066 A CN103100066 A CN 103100066A
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Abstract
The invention discloses a traditional Chinese medicine composition for tranquilizing and allaying excitement and a preparation method thereof. The traditional Chinese medicine composition contains the components of medicinal materials in parts by weight: 6 parts of immature bitter orange, 6 parts of bamboo shavings, 9 parts of pericarpium citri reticulatae, 12 parts of tuckahoe, 9 parts of root of common peony, 6 parts of cassia twig, 6 parts of ginger, 4 parts of Chinese-date, 6 parts of liquorice, 12 parts of rhizoma acori graminei, 15 parts of raw jujube kernel, 15 parts of fried jujube kernel, 6 parts of rhizoma pinellinae praeparata and 4 parts of enzyme microorganism. The pharmaceutical composition of the traditional Chinese medicine for tranquilizing and allaying excitement disclosed by the invention is an oral capsule of the traditional Chinese medicine composition, has the effects of sleeping, clearing trouble, removing nightmare, and restoring memory and comprehensive ability, and is used for treating insomnia and poor sleep quality. Compared with the like products in the market at present, the traditional Chinese medicine composition has the advantages of being small in dosage, convenient to take, rapid to absorb, high in bioavailability, high in curative effective, free of side effect, stable in quality, simple in manufacturing technique and the like.
Description
Technical field
The invention belongs to Chinese medicine health-care medicine technical field, particularly a kind of Chinese medicine combination for tranquillizing and allaying excitement and preparation method thereof.
Background technology
Sleep 1/3rd of the life that accounted for, under the high strength life stress, by not having enough sleep of causing of a variety of causes, difficulty falling asleep, mental fatigue, poor memory, absent minded etc., can't fall asleep, symptom not sleep well, sleep disorder, be a cup too low, depressive anxiety.Although many patients can fall asleep, can not recover from fatigue can feel to sleep, still have feeling of fatigue after waking up, cannot not wake up clear-headedly, sleep sensory disturbance, the sense of reality of sleep insuffience.Many patients are very tired, and also sleepy is felt, can lie on a bed is exactly can't fall asleep, and that tosses about thinks something, calmly do not get off, and obviously reduce the length of one's sleep.Due to insomnia and sleep quality bad, affect work, affect quality of life, work, live and bring very big misery to the patient.Take sleeping pill, dosage is large, and medicining times is many, and the time is long, and side effect is strong, is a cup too low after wakeing up, and feels dizzy, and work efficiency is low.
Summary of the invention
The purpose of this invention is to provide a kind of pure Chinese medicine combination for tranquillizing and allaying excitement and preparation method thereof, the present invention has tranquillizing and allaying excitement, sleeps peacefully, is tired of clearly, goes nightmare, regains the strength of memory, the effect of understandability, be used for insomnia and the bad disease of sleep quality, and taking dose is little, taking convenience, absorption is fast, bioavailability is high, easy to carry, quantitatively accurate, steady quality.
Technical scheme of the present invention is: design a kind of pure Chinese medicine combination for tranquillizing and allaying excitement, it is characterized in that crude drug composition and weight proportion thereof that it contains are: 6 parts of Fructus Aurantii Immaturuss, 6 parts of Caulis Bambusae In Taenia, 9 parts of Pericarpium Citri Reticulataes, 12 parts, Poria, 9 parts of Radix Paeoniae Rubra, 6 parts of Ramulus Cinnamomi, 6 parts, Rhizoma Zingiberis Recens, 4 parts, Fructus Jujubae, 6 parts, Radix Glycyrrhizae, 12 parts of Rhizoma Acori Graminei, give birth to 4 parts of 15 parts of Semen Ziziphi Spinosaes, 15 parts of Semen Ziziphi Spinosae (parched)s, 6 parts of Rhizoma Pinelliae Preparatum and enzymatic microorganism.
The preparation method of described a kind of pure Chinese medicine combination for tranquillizing and allaying excitement is characterized in that it comprises the following steps:
1) take raw material by following weight ratio: 6 parts of Fructus Aurantii Immaturuss, 6 parts of Caulis Bambusae In Taenia, 9 parts of Pericarpium Citri Reticulataes, 12 parts, Poria, 9 parts of Radix Paeoniae Rubra, 6 parts of Ramulus Cinnamomi, 6 parts, Rhizoma Zingiberis Recens, 4 parts, Fructus Jujubae, 6 parts, Radix Glycyrrhizae, 12 parts of Rhizoma Acori Graminei, give birth to 4 parts of 15 parts of Semen Ziziphi Spinosaes, 15 parts of Semen Ziziphi Spinosae (parched)s, 6 parts of Rhizoma Pinelliae Preparatum and enzymatic microorganism;
2) with the above-mentioned raw materials except enzymatic microorganism, add 10 times of water gagings and decoct 3 times, each one hour, merging filtrate at 45-50 ℃ of temperature, was concentrated into relative density and is 1.10 ~ 1.30 extractum with filtrate; Be that 95% ethanol is made wetting agent with mass percent concentration, abundant mixing, granulation, dry below 60 ℃;
3) excessively evenly mix with 4 parts of enzymatic microorganism after 24 mesh sieves, upper capsule filling machine carries out filling, gets final product.
Advantage of the present invention is: drug regimen involved in the present invention has the kidney invigorating and essence nourishing, tranquilizing by nourishing the heart, strengthening the body resistance, the Fructus Aurantii Immaturus dispelling the stagnated QI, removing food stagnancy, Caulis Bambusae In Taenia clearing away heat to stop vomiting, the clearing away phlegm dissipating depression of QI, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, Poria invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, Radix Paeoniae Rubra clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, Ramulus Cinnamomi diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, the diaphoresis of Rhizoma Zingiberis Recens cold expelling, preventing phlegm from forming and stopping coughing, stomach function regulating preventing or arresting vomiting, the Fructus Jujubae invigorating spleen and reinforcing stomach, benefiting qi and nourishing blood; Radix Glycyrrhizae is delayed healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening except pathogenic heat; Rhizoma Acori Graminei removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae; Semen Ziziphi Spinosae (parched) calm the nerves nourishing, strengthening body are given birth to Semen Ziziphi Spinosae and are controlled and do not wake up clear-headed, the Rhizoma Pinelliae Preparatum drying dampness to eliminate phlegm, and stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, enzymatic microorganism can strengthen the drug absorption utilization rate, improves the patient body microbiota, the reparation of enhancing health, regeneration, self-healing function.
Chinese medicine composition taking dose of the present invention is little, taking convenience, absorption is fast, bioavailability is high, easy to carry, quantitatively accurately, steady quality.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.
Embodiment 1
A kind of preparation method of the pure Chinese medicine combination for tranquillizing and allaying excitement adopts following steps to make:
1) take raw material by following weight ratio: 6 parts of Fructus Aurantii Immaturuss, 6 parts of Caulis Bambusae In Taenia, 9 parts of Pericarpium Citri Reticulataes, 12 parts, Poria, 9 parts of Radix Paeoniae Rubra, 6 parts of Ramulus Cinnamomi, 6 parts, Rhizoma Zingiberis Recens, 4 parts, Fructus Jujubae, 6 parts, Radix Glycyrrhizae, 12 parts of Rhizoma Acori Graminei, give birth to 4 parts of 15 parts of Semen Ziziphi Spinosaes, 15 parts of Semen Ziziphi Spinosae (parched)s, 6 parts of Rhizoma Pinelliae Preparatum and enzymatic microorganism;
2) with the above-mentioned raw materials except enzymatic microorganism, add 10 times of water gagings and decoct 3 times, each one hour, merging filtrate at 45-50 ℃ of temperature, was concentrated into relative density and is 1.10 ~ 1.30 extractum with filtrate; Be that 95% ethanol is made wetting agent with mass percent concentration, abundant mixing, granulation, dry below 60 ℃;
3) excessively evenly mix with 4 parts of enzymatic microorganism after 24 mesh sieves, upper capsule filling machine carries out filling, gets final product.
This Chinese medicine combination for tranquillizing and allaying excitement of the embodiment of the present invention 1, the clinical observation that Cure for insomnia and sleep quality are bad
1 data and method
1.1 physical data
Insomnia and bad patient's 1400 examples of sleep quality of selecting outpatient service to receive treatment voluntarily, male's 700 examples, women's 700 examples, age 2l～78 years old, average 42.6 years old.All cases all through making a definite diagnosis all meet the insomnia and sleep quality bad.MethodsThe cases enrolled outbreak all 〉=20 times.And expection can be adhered to completing at least one course for the treatment of.Be divided at random treatment group 1, treatment group 2, treatment group 3, and matched group, every group of 350 examples; Each is organized the patient age symptom and consists of without significant difference.Has comparability (P〉0.05).
1.2 Therapeutic Method
The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 use embodiment of the present invention 1, every day three times, one time two, 10 days is a course for the treatment of.The treatment group 2 use treasured of calming the nerves, Hebei Dongsheng quintessence pharmaceutical manufacturing, one time 1～2 bag, 3 times on the one; Treatment group 3 is used ANSHEN BUXIN WAN, and the Beijing Tongrentang Technology Development Co.ltd. Pharmaceutical Factory produces, 15 balls, 3 times on the one.
2 results
2.1 curative effect determinate standard
Be almost recovered: observe after drug withdrawal and do not recur in 3 months.Produce effects: sleep disorder occurs once in a while.Effectively: attack times reduces, sx↓.Invalid: attack times and symptom are all unchanged.
2.2 therapeutic outcome
3 discuss
The traditional Chinese medical science thinks, yin and yang imbalance is a important pathogenesis of insomnia, " Wei Weihe of battalion, the cloudy deficiency of vital energy; defend gas and walk alone in sun, do not enter the moon, therefore insomnia ", incoordination between the spleen and stomach, the gallbladder stomach is uncomfortable, disturb in food stagnation, phlegm-fire the mind can cause lie awake with sth. on one's mind and worried, but disturb mind induced insomnia in pathogen.Being insomnia, often internal injury is common, and the many apoplexy due to deficiency of card feelings are held reality under the arm.From the aspect of void, many deficiency of vital energys or deficiency of both QI and YIN; From the aspect of reality, excessive phlegm, many stasis of bloods.The card of being insomnia is person of a specified duration both, not from expectorant, the stasis of blood, heat, empty four words.Therefore, the card of being insomnia, majority is compound card, and sees that singly empty or real person is less.
Must trace to its source produces the reason of yin and yang imbalance, may control just that it is basic, conditioning viscera, adopt pure Chinese medicine composition the kidney invigorating and essence nourishing, tranquilizing by nourishing the heart, strengthening the body resistance, thereby reach the control outbreak, remove the purpose of symptom so that recovery from illness, and then illustrate that in this invention, the affiliated prescription of embodiment 1 is reliably effective.
Technique, pharmaceutical test method and production technology standard that the present invention does not have to describe in detail belong to existing technique, existing pharmaceutical test method and production technology standard, belong to the common practise not narration one by one here of the industry.
Claims (2)
1. pure Chinese medicine combination that is used for tranquillizing and allaying excitement is characterized in that crude drug composition and weight proportion thereof that it contains are: 6 parts of Fructus Aurantii Immaturuss, 6 parts of Caulis Bambusae In Taenia, 9 parts of Pericarpium Citri Reticulataes, 12 parts, Poria, 9 parts of Radix Paeoniae Rubra, 6 parts of Ramulus Cinnamomi, 6 parts, Rhizoma Zingiberis Recens, 4 parts, Fructus Jujubae, 6 parts, Radix Glycyrrhizae, 12 parts of Rhizoma Acori Graminei, give birth to 4 parts of 15 parts of Semen Ziziphi Spinosaes, 15 parts of Semen Ziziphi Spinosae (parched)s, 6 parts of Rhizoma Pinelliae Preparatum and enzymatic microorganism.
2. the preparation method of a kind of pure Chinese medicine combination for tranquillizing and allaying excitement according to claim 1 is characterized in that it comprises the following steps:
1) take raw material by following weight ratio: 6 parts of Fructus Aurantii Immaturuss, 6 parts of Caulis Bambusae In Taenia, 9 parts of Pericarpium Citri Reticulataes, 12 parts, Poria, 9 parts of Radix Paeoniae Rubra, 6 parts of Ramulus Cinnamomi, 6 parts, Rhizoma Zingiberis Recens, 4 parts, Fructus Jujubae, 6 parts, Radix Glycyrrhizae, 12 parts of Rhizoma Acori Graminei, give birth to 4 parts of 15 parts of Semen Ziziphi Spinosaes, 15 parts of Semen Ziziphi Spinosae (parched)s, 6 parts of Rhizoma Pinelliae Preparatum and enzymatic microorganism;
2) with the above-mentioned raw materials except enzymatic microorganism, add 10 times of water gagings and decoct 3 times, each one hour, merging filtrate at 45-50 ℃ of temperature, was concentrated into relative density and is 1.10 ~ 1.30 extractum with filtrate; Be that 95% ethanol is made wetting agent with mass percent concentration, abundant mixing, granulation, dry below 60 ℃;
3) excessively evenly mix with 4 parts of enzymatic microorganism after 24 mesh sieves, upper capsule filling machine carries out filling, gets final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550580A (en) * | 2013-10-31 | 2014-02-05 | 王梦薇 | Traditional Chinese medicine composition for treating insomnia |
| CN103585393A (en) * | 2013-11-25 | 2014-02-19 | 禤燕华 | Traditional Chinese medicine composition for treating insomnia and dreaminess and preparation method thereof |
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| CN1840166A (en) * | 2006-01-11 | 2006-10-04 | 东莞市杏林春中医药研究所 | Wendan decoction modern traditional Chinese medicine oral preparation and production method thereof |
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| CN1840166A (en) * | 2006-01-11 | 2006-10-04 | 东莞市杏林春中医药研究所 | Wendan decoction modern traditional Chinese medicine oral preparation and production method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550580A (en) * | 2013-10-31 | 2014-02-05 | 王梦薇 | Traditional Chinese medicine composition for treating insomnia |
| CN103585393A (en) * | 2013-11-25 | 2014-02-19 | 禤燕华 | Traditional Chinese medicine composition for treating insomnia and dreaminess and preparation method thereof |
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Application publication date: 20130515 |