CN103099756B - Acne-removing and anti-allergic cosmetic cream and preparation method thereof - Google Patents
Acne-removing and anti-allergic cosmetic cream and preparation method thereof Download PDFInfo
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- CN103099756B CN103099756B CN201310040209.6A CN201310040209A CN103099756B CN 103099756 B CN103099756 B CN 103099756B CN 201310040209 A CN201310040209 A CN 201310040209A CN 103099756 B CN103099756 B CN 103099756B
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- 206010000496 acne Diseases 0.000 title claims abstract description 51
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 49
- 230000003266 anti-allergic effect Effects 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 239000008278 cosmetic cream Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 54
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims abstract description 51
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 26
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 24
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims abstract description 24
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 claims abstract description 19
- 235000019400 benzoyl peroxide Nutrition 0.000 claims abstract description 19
- 235000012716 cod liver oil Nutrition 0.000 claims abstract description 19
- 239000003026 cod liver oil Substances 0.000 claims abstract description 19
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 claims abstract description 19
- 229960000520 diphenhydramine Drugs 0.000 claims abstract description 19
- 239000003079 shale oil Substances 0.000 claims abstract description 19
- 229940111630 tea tree oil Drugs 0.000 claims abstract description 19
- 239000010677 tea tree oil Substances 0.000 claims abstract description 19
- 235000021355 Stearic acid Nutrition 0.000 claims abstract description 18
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 claims abstract description 18
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 18
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000008117 stearic acid Substances 0.000 claims abstract description 18
- 239000004342 Benzoyl peroxide Substances 0.000 claims abstract description 13
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 13
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 13
- 239000011718 vitamin C Substances 0.000 claims abstract description 13
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 12
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims abstract description 12
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims abstract description 12
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229940046009 vitamin E Drugs 0.000 claims abstract description 12
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 12
- 239000011709 vitamin E Substances 0.000 claims abstract description 12
- 238000003756 stirring Methods 0.000 claims description 20
- 238000006277 sulfonation reaction Methods 0.000 claims description 18
- GYCKQBWUSACYIF-UHFFFAOYSA-N o-hydroxybenzoic acid ethyl ester Natural products CCOC(=O)C1=CC=CC=C1O GYCKQBWUSACYIF-UHFFFAOYSA-N 0.000 claims description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000012567 medical material Substances 0.000 claims description 10
- 229930003231 vitamin Natural products 0.000 claims description 9
- 235000013343 vitamin Nutrition 0.000 claims description 9
- 239000011782 vitamin Substances 0.000 claims description 9
- 229940088594 vitamin Drugs 0.000 claims description 9
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 9
- 229940075507 glyceryl monostearate Drugs 0.000 claims description 6
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 claims description 6
- 230000001476 alcoholic effect Effects 0.000 claims description 5
- 229960003328 benzoyl peroxide Drugs 0.000 claims description 5
- 238000004821 distillation Methods 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 229940075495 isopropyl palmitate Drugs 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 229960004274 stearic acid Drugs 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical group C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 2
- 201000004624 Dermatitis Diseases 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 239000003814 drug Substances 0.000 abstract description 3
- 230000008929 regeneration Effects 0.000 abstract description 3
- 238000011069 regeneration method Methods 0.000 abstract description 3
- 210000004927 skin cell Anatomy 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 208000020154 Acnes Diseases 0.000 abstract 2
- 239000006071 cream Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 16
- 239000000203 mixture Substances 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 230000002804 anti-anaphylactic effect Effects 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 241000186427 Cutibacterium acnes Species 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000000895 acaricidal effect Effects 0.000 description 1
- 239000000642 acaricide Substances 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000002052 anaphylactic effect Effects 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000000556 factor analysis Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000000745 gonadal hormone Substances 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229940055019 propionibacterium acne Drugs 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
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Priority Applications (1)
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CN201310040209.6A CN103099756B (en) | 2013-02-01 | 2013-02-01 | Acne-removing and anti-allergic cosmetic cream and preparation method thereof |
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CN201310040209.6A CN103099756B (en) | 2013-02-01 | 2013-02-01 | Acne-removing and anti-allergic cosmetic cream and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
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CN103099756A CN103099756A (en) | 2013-05-15 |
CN103099756B true CN103099756B (en) | 2014-07-16 |
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CN201310040209.6A Active CN103099756B (en) | 2013-02-01 | 2013-02-01 | Acne-removing and anti-allergic cosmetic cream and preparation method thereof |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8986755B1 (en) * | 2013-12-05 | 2015-03-24 | Sherry May Raymond-Coblantz | Skin moisturizer |
US8986752B1 (en) * | 2013-12-05 | 2015-03-24 | Sherry May Raymond-Coblantz | Skin care treatment |
CN103860424A (en) * | 2014-02-13 | 2014-06-18 | 上海珍馨化工科技有限公司 | Tea tree essential oil whitening cream |
CN105395393A (en) * | 2015-11-25 | 2016-03-16 | 广州丹奇日用化工厂有限公司 | Skin care product composition with acne mark removing function and acne treatment cream |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1090173A (en) * | 1993-10-28 | 1994-08-03 | 广东医学院医药科技开发中心 | A kind of prescription and preparation thereof that promotes that drug transdermal absorbs |
CN101007101A (en) * | 2007-02-07 | 2007-08-01 | 陈炜 | Synergistic composition containing benzoyl peroxide |
CN101264049A (en) * | 2007-03-13 | 2008-09-17 | 李春风 | Multifunctional beauty treatment cream |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPN892496A0 (en) * | 1996-03-25 | 1996-04-18 | Technical Consultancy Services Pty Limited | Acne treatment |
-
2013
- 2013-02-01 CN CN201310040209.6A patent/CN103099756B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1090173A (en) * | 1993-10-28 | 1994-08-03 | 广东医学院医药科技开发中心 | A kind of prescription and preparation thereof that promotes that drug transdermal absorbs |
CN101007101A (en) * | 2007-02-07 | 2007-08-01 | 陈炜 | Synergistic composition containing benzoyl peroxide |
CN101264049A (en) * | 2007-03-13 | 2008-09-17 | 李春风 | Multifunctional beauty treatment cream |
Non-Patent Citations (3)
Title |
---|
JP特表2000-507248A 2000.06.13 |
张保如等.过氧化苯甲酰霜治疗寻常性痤疮的临床观察.《中国医学科学院学报》.1991,第13卷(第6期),463-465. |
过氧化苯甲酰霜治疗寻常性痤疮的临床观察;张保如等;《中国医学科学院学报》;19911231;第13卷(第6期);463-465 * |
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CN103099756A (en) | 2013-05-15 |
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Owner name: GUANGZHOU BAIYUN TIANFANG COSMETICS FACTORY Free format text: FORMER OWNER: SHENZHEN GUAFEN BIOTECHNOLOGY CO., LTD. Effective date: 20140604 Free format text: FORMER OWNER: DENG JINHUI Effective date: 20140604 |
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Inventor after: Liang Yiwen Inventor before: Deng Jinhui |
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Free format text: CORRECT: ADDRESS; FROM: 518100 SHENZHEN, GUANGDONG PROVINCE TO: 510000 GUANGZHOU, GUANGDONG PROVINCE Free format text: CORRECT: INVENTOR; FROM: DENG JINHUI TO: LIANG YIWEN |
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Effective date of registration: 20140604 Address after: New town, Baiyun District of Guangzhou City, Guangdong Province, the 510000 Great Qing village industrial park Applicant after: GUANGZHOU CITY BAIYUN DISTRICT TIANFANG COSMETIC FACTORY Address before: 518100, No. 201, No. twenty-eight, building A, west side, two road, Baoan District District, Shenzhen, Guangdong Applicant before: SHENZHEN GUAFEN BIOTECHNOLOGY Co.,Ltd. Applicant before: Deng Jinhui |
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Owner name: GUANGZHOU QIANYI INTERNATIONAL TRADING CO., LTD. Free format text: FORMER OWNER: GUANGZHOU BAIYUN TIANFANG COSMETICS FACTORY Effective date: 20141222 |
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Effective date of registration: 20141222 Address after: 510000, Guangdong, Guangzhou Yuexiu District building two road 6, the first floor of building 4 D10 room Patentee after: GUANGZHOU QIANYI INTERNATIONAL TRADE Co.,Ltd. Address before: New town, Baiyun District of Guangzhou City, Guangdong Province, the 510000 Great Qing village industrial park Patentee before: GUANGZHOU CITY BAIYUN DISTRICT TIANFANG COSMETIC FACTORY |
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Effective date of registration: 20161009 Address after: New town, Baiyun District of Guangzhou City, Guangdong Province, the 510000 Great Qing village industrial park Patentee after: GUANGZHOU CITY BAIYUN DISTRICT TIANFANG COSMETIC FACTORY Address before: 510000, Guangdong, Guangzhou Yuexiu District building two road 6, the first floor of building 4 D10 room Patentee before: GUANGZHOU QIANYI INTERNATIONAL TRADE Co.,Ltd. |
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Effective date of registration: 20240103 Address after: Building 1, 101, 201, No. 2 Liangyuan Second Road, Zhongluotan Town, Baiyun District, Guangzhou City, Guangdong Province, 510080 Patentee after: Guangzhou Tianfang traditional Chinese Medicine Technology Co.,Ltd. Address before: 510000 Dabuyuan Industrial Zone, Qinghu Village, Xinshi Town, Baiyun District, Guangzhou City, Guangdong Province Patentee before: GUANGZHOU CITY BAIYUN DISTRICT TIANFANG COSMETIC FACTORY |
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Effective date of registration: 20240223 Address after: Room 2002, No. 5 Huating Road, Tianhe District, Guangzhou City, Guangdong Province, 510630 Patentee after: Liang Yiwen Country or region after: China Address before: Building 1, 101, 201, No. 2 Liangyuan Second Road, Zhongluotan Town, Baiyun District, Guangzhou City, Guangdong Province, 510080 Patentee before: Guangzhou Tianfang traditional Chinese Medicine Technology Co.,Ltd. Country or region before: China |
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