CN103037817B

CN103037817B - For the method and system that the oral area of furcation opens

Info

Publication number: CN103037817B
Application number: CN201180025670.3A
Authority: CN
Inventors: H·保让; M·考桑迪
Original assignee: Advanced Bifurcation Systems Inc
Current assignee: Advanced Bifurcation Systems Inc
Priority date: 2010-03-24
Filing date: 2011-03-24
Publication date: 2015-11-25
Anticipated expiration: 2031-03-24
Also published as: CN103037817A; CA2794279A1; WO2011119880A1; AU2011232358B2; WO2011119879A1; EP2549949B1; EP4275660A3; EP3616655B1; EP2549950A1; AU2011232358A1; EP2549949A4; EP2549949A1; EP2549950A4; EP4275660A2; EP3616655A1

Abstract

Process a system for bifurcated vascular, this system comprises first and second delivery conduits respectively with expandable members.There is the Bracket setting of side opening on the second delivery conduit.A part for first delivery conduit is arranged on the part below of support.First delivery conduit can slide relative to the second delivery conduit, and the first delivery conduit is through side opening.The expansion of the first expandable members makes the portions of proximal of the support in main split's vascular expand, and the expansion of the second expandable members makes the distal part of the support in the branch vessel of side expand.

Description

For the method and system that the oral area of furcation opens

Background of invention

The present invention relates to medical treatment device, and relate more specifically to support installing and the process of bifurcated vascular.Support is a kind of implantable shelf, the conveying of this implantable shelf usual percutaneous and in vein, tremulous pulse or other tubular body organs, launch to process obturation, narrow, aneurysm, subside, peel off or weakens, the vascular of pathological changes or exception expansion or blood vessel wall.Support is radial dilatation on the spot, expands thus and/or supports blood vessel wall or organ wall.Specifically, support is transplanted to crown, heart, lung, neural with blood vessel, peripheral blood vessel, breast, gastrointestinal tract and reproductive system usually, and it is interior to reinforce these organs to be successfully transplanted to urethra, bile duct, esophagus, tracheobronchial tree and brain.

Support is generally used for by preventing from the elastic recoil of blood vessel wall and reinvent blood vessel wall improving angioplasty results, and for by endoceliac interior diaphragm pressed together processing the blood vessel wall that the balloon angioplasty art due to coronary artery and peripheral arterial causes and peel off peeling off position.Conventional bracket is used for the more complicated vascular problems of limited success rate process, bifurcation or neighbouring damage in such as vascular system, and wherein secondary tremulous pulse separates from usual larger aorta.

Conventional bracket technology is launched relatively well.The usual feature of conventional stent designs is straight tube, the longitudinally axis monotype alveolate texture of through translation, structure or pattern repeatedly.In multiple support Design, repetitive structure, structure or pattern have the balloon catheter part of support member and connection, and balloon catheter part can hinder the blood flow at place of vessel bifurcation portion.

In addition, the structure of the balloon catheter part of support member and connection may hinder the use of postoperative device to process the sub-vascular in vessel bifurcation region.Such as, at the pathological tissues due to displacement (such as, due to speckle displacement or " clearing the snow "), obturation, vasospasm, when having interior diaphragm or do not have the stripping of interior diaphragm, thrombosis, thromboembolism and/or other his angiopathy and make the process suboptimum of mother lode pipe, the expansion of parent intracavity first support can prevent doctor submounts to be inserted through the sub-vascular oral area in vessel bifurcation portion.Consider the Factors of Contradiction design rule support of coverage rate and touching property.Such as, in order to improve coverage rate, the large I of honeycomb texture of support minimizes to support blood vessel wall best, prevents thus or reduces tissue prolapse.In order to improve touching property, unit size can be maximum to provide blood flow and the submounts that may implant in the future to the touching property of sub-vascular, prevents " support obstruction " thus and make the amount of embedded material minimum.Rule support Design usually when attempting solution two Consideration in order to another consideration factor sacrifices a Consideration.The problem that the present inventor considers comprises submounts and blocks, worries speckle transfer, entirely shuts and the difficulty of process, these problems continue to impel the present inventor's development of new induction system, and this system is more convenient, safer and more reliably for the treatment of above-mentioned various angiopathy.Although conventional bracket is generally used for clinical course, clinical data shows, these supports are the restenosiss that can not prevent in-stent restenosis (ISR) or neointimal hyperplasia from causing completely.In-stent restenosis is the stenosis or occlusion that tremulous pulse occurs again in the region covered by support after stenter to implant.In-stent restenosis can be suffered with the patient of Coronary stents process.

Make the amount that many pharmacology attempt reducing the restenosis that neointimal hyperplasia causes.Many these are attempted relating to and are carried via systemic drug that is oral or intravascular injection.But the success rate of whole body transportation scheme is restricted.

The whole body conveying of medicine is inherent limited, because be difficult to the constant drug conveying being implemented to affected area, and the medicine putting on whole body circulates through peak concentration and valley usually, causes the property of medicine and invalid time cycle.Therefore, in order to effectively, locally anti-restenosis drugs should be carried.A kind of method of local drug delivery utilizes support as means of delivery.Such as, the support that inoculation has the endotheliocyte of transfection to express bacteria beta-galactosidase or tissue type plasminogen activator is used as the means of delivery of human cytokines." SeedingofIntravascularStentsWithGeneticallyEngineeredEnd othelialCells, " Circulation(circulation see people such as such as Dichek, D.A.), 80:1347-1353 (1989).United States Patent (USP) the 5th, 679, No. 400, No. WO91/12779th, International Patent Publication being entitled as " IntraluminalDrugElutingProsthesis " and No. WO90/13332nd, International Patent Publication being entitled as " StentWithSustainedDrugDelivery " disclose the holder device can carrying anti-platelet agents, anticoagulant, migration inhibitor agent, antimetabolite and other anti-restenosis drugs.United States Patent (USP) 6,273,913,6,383,215,6,258,121,6,231,600,5,837,008,5,824,048,5,679,400 and 5,609,629 have taught the support scribbling various medicament, such as rapamycin, 17-β-estradiol, paclitaxel and dexamethasone.This patent and all patents that other is mentioned all with see mode include in herein.In addition, in the document included in see mode herein definition and use term inconsistent with term definition provided herein or contrary, use term definition provided in this article and the definition of this term in inapplicable document.

Therefore, for the problem of the current brackets technology provided, need the stent delivery system and the method that are particularly useful for processing bifurcated vascular improved.By the present invention meet in these objects at least some.

Summary of the invention

The present invention relates to the method for transfer gantry in bifurcated vascular and induction system.Each embodiment can be configured to put support at least partially with in a part for sub-vascular at mother lode pipe.

In a first aspect of the present invention, a kind of method processing bifurcated vascular comprises: provide the first delivery conduit and the second delivery conduit.First delivery conduit comprises the first elongated axostylus axostyle and is positioned at the first expandable members near the distal end of the first elongated axostylus axostyle.The support that second delivery conduit comprises the second elongated axostylus axostyle, is positioned at the second expandable members near the distal end of the second elongated axostylus axostyle and is arranged in the second expandable members.This support has sidewall, and this sidewall has the side opening through it.A part for first elongated axostylus axostyle is arranged on below support, and the first elongated axostylus axostyle is through the side opening in support.First expandable members is in the distally of the second expandable members.First delivery conduit and the second delivery conduit advance to furcation through vascular.Furcation comprises the main split's vascular with pathological changes portion of main split and extends from main split and have the side branch in pathological changes portion of side branch.Vascular can adopt standard blood vessel angioplasty technique to connect wire.In certain embodiments, the first conduit can be loaded into main split's guide line, and the second conduit can be arranged on side branch guide line.System is advanced, till Bracket setting is in main split and side branch.First expandable members is advanced, until the first expandable members till furcation is located in main split.First elongated axostylus axostyle is retracted relative to the second elongated axostylus axostyle proximad, thus, first elongated axostylus axostyle is retracted below the portions of proximal of support, and a part for the first expandable members is located at below support, and another part of the first expandable members does not still retrain by support, and in main split, be arranged at the distally of support inboard aperture.First expandable members radial dilatation, makes the portions of proximal of support expand into thus and coordinates with pathological changes portion of main split and main split's wall, and also make side opening expand.Second expandable members radial dilatation, makes the distal part of support expand into thus and coordinates with the wall of the pathological changes portion in the branch of side and side branch.Then, two expandable members can simultaneously radial dilatation.

In the preferred embodiment, at least one support has sidewall, and this sidewall is with the side opening extended through it or hole, and a part for delivery conduit can pass this side opening.But this does not also mean that restriction, and in any embodiment disclosed herein, person of skill in the art will appreciate that, support can have other exit position any.Therefore, no matter export the side opening in rack side wall or be arranged in another part of support, delivery conduit all can pass this outlet.

First and second delivery conduits all can advance, until operator feels to the resistance be advanced further.This resistance is provided by being separated when the first elongated axostylus axostyle and the second elongated axostylus axostyle advance against the knuckle between main split with side branch between two axostylus axostyles.

First delivery conduit can comprise the first radiopaque labelling be disposed adjacent with the proximal region of the first expandable members, and the second delivery conduit can comprise the second radiopaque labelling be disposed adjacent with the proximal region of the second expandable members.This retraction step can comprise makes the first elongated axostylus axostyle retract, until the first radiopaque labelling and the second radiopaque markers align.Second elongated axostylus axostyle can comprise exchange inner chamber, and this retraction step can comprise make the first elongated axostylus axostyle by exchange inner chamber retract slidably.First elongated axostylus axostyle and the second elongated axostylus axostyle can be arranged in the central passage of capture duct, and retraction step can comprise the first elongated axostylus axostyle is retracted slidably by central passage.Capture duct can comprise punched areas, and the method also can comprise by punched areas separately and peeled off from the first and second elongated axostylus axostyles by capture duct.Second elongated axostylus axostyle can comprise card accessory, and this card accessory is configured to receive and keep the first elongated axostylus axostyle, and step of retracting can comprise the first elongated axostylus axostyle is retracted slidably along card accessory.First elongated axostylus axostyle and the second elongated axostylus axostyle can be arranged in polymer pipe, and this polymer pipe has the central passage through it, and retraction step can comprise the first elongated axostylus axostyle is retracted slidably by central passage.

First expandable members or the second expandable members can comprise utricule, and the expansion of the expandable members of correspondence can comprise inflation utricule.The method also can be included in first expandable members expansion after and second expandable members expansion before make first expandable members shrink.The expansion of support can comprise makes support expand differentially, to make the diameter of the proximal region of the support of expansion larger than the diameter of the distal region of expandable stent.

The method also comprises to be made the first and second expandable members expand into be fitted to each other simultaneously, guarantee that the portions of proximal of support coordinates with the pathological changes portion in main split and guarantees that the distal part of support coordinates with the pathological changes portion in the branch of side thus, and guarantee that the side opening in support is aimed at main split.Main split can have roughly similar diameter with side branch.The method also can comprise makes therapeutic agent be eluted in pathological changes portion of main split or pathological changes portion of side branch from support or expandable members.Therapeutic agent can comprise anti-restenosis agent.

In still another aspect of the invention, a kind of system processing furcation comprises the first delivery conduit and the second delivery conduit.First delivery conduit comprises the first elongated axostylus axostyle and first expandable members adjacent with the distal end of the first elongated axostylus axostyle with nearside and distal end.Second delivery conduit comprise the second elongated axostylus axostyle with nearside and distal end, second expandable members adjacent with the distal end of the second elongated axostylus axostyle and be arranged in the second expandable members can radial dilatation support.This support comprises sidewall, and this sidewall has the side opening through it, and this support also has collapsed configuration and expanded configuration.Under collapsed configuration, support is suitable for being transported to furcation, and under expanded configuration, the wall of main split of support supporting furcation and the wall of side branch.The Part I of the first elongated axostylus axostyle is arranged on below the portions of proximal of support.Equally, the first elongated axostylus axostyle, through side opening, is arranged in the distal part of support to make the Part II of the first elongated axostylus axostyle.When support is in collapsed configuration, the first elongated axostylus axostyle can slide axially relative to the second elongated axostylus axostyle.

In the preferred embodiment, at least one support has sidewall, and this sidewall is with the side opening extended through it or hole, and a part for delivery conduit can pass side opening.But this does not also mean that restriction, and in any embodiment disclosed herein, person of skill in the art will appreciate that, support can have other exit position any.Therefore, no matter export the side opening in rack side wall or be arranged in another part of support, delivery conduit all can pass this outlet.

First expandable members and the second expandable members can be expanded independently of one another.First expandable members or described second expandable members can comprise utricule.Each in first and second delivery conduits comprises inflation lumen and/or guidewire lumen.First delivery conduit can comprise distal guide line opening in the first elongated axostylus axostyle distal end and nearside guide line opening.The proximal end of the comparable first elongated axostylus axostyle of nearside guide line opening is opened closer to distal guide line open space.In other embodiments, nearside guide line opening comparable distal guide line opening is closer to the proximal end of the first elongated axostylus axostyle.Guidewire lumen in first delivery conduit can be configured to receive guide line slidably, and guidewire lumen distally can extend to nearside guide line opening by guide line opening.

Second delivery conduit can comprise distal guide line opening in the second elongated axostylus axostyle distal end and nearside guide line opening.Nearside guide line opening can obtain nearer with distal guide line open space compared with the proximal end of the second elongated axostylus axostyle.In other embodiments, nearside guide line opening compared with distal guide line opening and the proximal end interval of the second elongated axostylus axostyle obtain nearer.Guidewire lumen in second delivery conduit can be configured to receive guide line slidably, and guidewire lumen distally can extend to nearside guide line opening by guide line opening.

First expandable members can be axially spaced with the second expandable members, to make the first expandable members in the distally of the second expandable members.The cross-sectional profiles of another expandable members of distal expandable element cross-section profiles comparable is little.First or second expandable members comprises active length, and this active length can comprise conical region, and thus, the diameter of the portions of proximal of this active length is greater than the diameter of the distal part of active length.

One of first elongated axostylus axostyle or the second elongated axostylus axostyle can comprise the region with guidewire lumen, inflation lumen and exchange inner chamber.Intracavity in another elongated axostylus axostyle can be slidably disposed on and exchange.Expandable members on another elongated axostylus axostyle can with to have the first elongated axostylus axostyle exchanging inner chamber axially spaced, to make the expandable members on another axostylus axostyle in the distally with the expandable members on the elongated axostylus axostyle exchanging inner chamber.This system can comprise capture duct, the central passage that this capture duct has proximal end, distal end, longitudinal axis and extends between proximal end and distal end.First elongated axostylus axostyle and the second elongated axostylus axostyle can be slidably disposed in central passage.Capture duct can prevent the first elongated axostylus axostyle and the second elongated axostylus axostyle from tangling.Capture duct can comprise the punched areas of longitudinally Axis Extension, and this punched areas extends at least in part between the nearside of capture duct and distal end, can peel off to make capture duct from the first and second elongated axostylus axostyles.Capture duct also can comprise locking mechanism, and this locking mechanism is used for keeping the first elongated axostylus axostyle and the second elongated axostylus axostyle releasedly.

One of first elongated axostylus axostyle or the second elongated axostylus axostyle can comprise card accessory, and this card accessory is configured to receive and keep another elongated axostylus axostyle.Another elongated axostylus axostyle can move axially through card accessory slidably, and the expandable members on another elongated axostylus axostyle can be axially spaced with the elongated axostylus axostyle with this card accessory, to make the distally of the expandable members of expandable members on the elongated axostylus axostyle with card accessory on another elongated axostylus axostyle.This system also can comprise polymer pipe, the central passage that this polymer pipe has proximal end, distal end, longitudinal axis and extends between proximal end and distal end.First elongated axostylus axostyle and the second elongated axostylus axostyle can be slidably disposed in central passage.Polymer pipe can prevent the first elongated axostylus axostyle and the second elongated axostylus axostyle from tangling.

This support can be balloon dilatation, self expandable or its combination.Support can be pressed unevenly and be held the second expandable members.Therapeutic agent can be arranged on can in radial dilatation support or the first or second expandable members, and therapeutic agent is suitable for from can an eluting radial dilatation support or the first or second expandable members.Therapeutic agent can comprise anti-restenosis agent.

First elongated axostylus axostyle can comprise setting radiopaque labelling thereon, and the second elongated axostylus axostyle can comprise setting radiopaque labelling thereon.When the first radiopaque labelling and the second radiopaque markers align, the working portion of the first expandable members can be aimed at the working portion of the second expandable members.A part for first expandable members can be arranged on below support, thus the expansion of the first expandable members also can make the portions of proximal of support expand, and the distal part of support keeps not expanding.First expandable members or the second expandable members can be expanded differentially, to make the diameter of the portions of proximal of differential expansion larger than the diameter of the distal part of differential expansion.Support also can be expanded differentially, and to make under expanded configuration, the diameter of the Part I of support is larger than the diameter of the Part II of support.

First delivery conduit can comprise the first guidewire lumen, and this first guidewire lumen extends at least in part between the proximal end of the first elongated axostylus axostyle and distal end.This system also can comprise the first guide line be slidably disposed in the first guidewire lumen.Second delivery conduit can comprise the second guidewire lumen, and this second guidewire lumen extends at least in part between the proximal end of the second elongated axostylus axostyle and distal end.This system also can comprise the second guide line be slidably disposed in the second guidewire lumen.Guide line can be attached to the distal end of the first elongated axostylus axostyle or the second elongated axostylus axostyle regularly.

Following about the description of the drawings in these and other embodiment is described in more detail.

Accompanying drawing explanation

Figure 1A-1B illustrates the exemplary embodiment with the system being enclosed within female conduit on guide line and quick recon conduit.

Fig. 2 A-2B illustrates the exemplary embodiment of the sub-conduit having and be enclosed within guide line and the system exchanging female conduit fast.

Fig. 3 A-3B illustrates the exemplary embodiment with the system exchanging female conduit and quick recon conduit fast.

Fig. 4 A-4B illustrates the exemplary embodiment of the female conduit having and be enclosed within guide line and the system being enclosed within the sub-conduit on guide line.

Fig. 5 A-5B illustrates another exemplary embodiment having capture duct, be enclosed within female conduit on guide line and the system of recon conduit fast.

Fig. 6 A-6B illustrates to have capture duct, be enclosed within sub-conduit on guide line and exchange another exemplary embodiment of system of female conduit fast.

Fig. 7 A-7B illustrates another exemplary embodiment having capture duct, exchange the system of female conduit and quick recon conduit fast.

Fig. 8 A-8B illustrates to have capture duct, be enclosed within the female conduit on guide line and be enclosed within another exemplary embodiment of system of the sub-conduit on guide line.

Fig. 9 A-9B illustrates the another exemplary embodiment having detachable capture duct, be enclosed within female conduit on guide line and the system of recon conduit fast.

Figure 10 A-10B illustrates to have detachable capture duct, be enclosed within sub-conduit on guide line and exchange the another exemplary embodiment of system of female conduit fast.

Figure 11 A-11B illustrates the another exemplary embodiment having detachable capture duct, exchange the system of female conduit and quick recon conduit fast.

Figure 12 A-12B illustrates to have detachable capture duct, be enclosed within the female conduit on guide line and be enclosed within the another exemplary embodiment of system of the sub-conduit on guide line.

Figure 13 A-13C illustrates the another exemplary embodiment having card accessory, be enclosed within female conduit on guide line and the system of recon conduit fast.

Figure 14 A-14C illustrates to have card accessory, be enclosed within sub-conduit on guide line and exchange the another exemplary embodiment of system of female conduit fast.

Figure 15 A-15B illustrates the another exemplary embodiment having card accessory, exchange the system of female conduit and quick recon conduit fast.

Figure 16 A-16C illustrates to have card accessory, be enclosed within the female conduit on guide line and be enclosed within the another exemplary embodiment of system of the sub-conduit on guide line.

Figure 17 A-17C illustrates the another exemplary embodiment having card accessory, be enclosed within female conduit on guide line and the system of recon conduit fast.

Figure 18 A-18C illustrates to have card accessory, be enclosed within sub-conduit on guide line and exchange the another exemplary embodiment of system of female conduit fast.

Figure 19 A-19C illustrates the another exemplary embodiment having card accessory, exchange the system of female conduit and quick recon conduit fast.

Figure 20 A-20C illustrates to have card accessory, be enclosed within the female conduit on guide line and be enclosed within the another exemplary embodiment of system of the sub-conduit on guide line.

Figure 21 A-21B illustrates the another exemplary embodiment with the system being enclosed within female conduit on guide line and quick recon conduit.

Figure 22 A-22B illustrates the another exemplary embodiment of the sub-conduit having and be enclosed within guide line and the system exchanging female conduit fast.

Figure 23 A-23B illustrates the another exemplary embodiment with the system exchanging female conduit and quick recon conduit fast.

Figure 24 A-24B illustrates the another exemplary embodiment of the female conduit having and be enclosed within guide line and the system being enclosed within the sub-conduit on guide line.

Figure 25 A-25B, 26A-26B, 27A-27B, 28A-28B, 29A-29B and 30A-30B illustrate the illustrative methods of process furcation.

Figure 31 illustrates the exemplary embodiment of support.

Figure 32 illustrates the exemplary embodiment of the system with female conduit and sub-conduit.

Figure 33 emphasizes the distal part of the system shown in Figure 32.

Figure 34 illustrates the aligning of Figure 32-33 medium-height trestle.

Figure 35 illustrates that pressure is held in the cross section of female conduit and the supravasal support of son.

Figure 36 illustrates and is arranged on female conduit and the supravasal support of son.

Figure 37 illustrates and is arranged on female conduit and the supravasal support of son and is arranged on sub supravasal support.

Figure 38 A-38M illustrates the illustrative methods of process furcation.

Figure 39 A-39H illustrates the various supports that can be used for treating furcation.

Figure 40-43 illustrates the exemplary embodiment of another stent delivery system.

Figure 44 A-44B illustrates the exemplary embodiment that utricule constructs.

Figure 45 illustrates another exemplary balloon catheter.

Detailed description of the invention

The present invention relates to the induction system for support being transported to the vessel bifurcation with main split and side branch, and be usually configured to cover a part for side branch and a part for main split at least in part.But, and do not mean that restriction, and person of skill in the art will appreciate that apparatus and method disclosed herein can be used for processing other region of health.

Academia does not slowly re-use main split and side branch model and term.Now generally accepted is that " mother " vascular is divided into two " sub-vasculars ", namely knuckle two vasculars below in anatomical structure.Look it is that the vascular that mother lode pipe continues has less corner angle usually.Other vascular general diameter is less and may be referred to as side branch or sub-vascular.Therefore, in this manual, term " main split " or " trunk " or " mother lode pipe " are used interchangeably.In addition, in this manual, term " side branch vessel " and " sub-vascular " are also used interchangeably.Term " female branch stent ", " trunk support " or " female support " are interchangeable, and term " side branch stent " also can exchange with term " submounts ".When mother stock branch vessel is divided into the branch of two equal sizes, still can think main split or mother lode pipe for one in branch, and side branch or sub-vascular can be thought by another branch.

Various catheter design can be adopted launch and locate female support and submounts.These conduits can be combined with the many guide lines ending at mother lode pipe and sub-vascular.These guide lines can be used for being convenient to introduce conduit, any angiopoiesis utricule, any support and/or support or utricule be suitably oriented in vascular.

Generally speaking, method disclosed herein can utilize a kind of conduit system, and this conduit system comprises the catheter body with mother lode pipe guidewire lumen and can independent operation be connected to the sub-vascular utricule of vascular body.Ascus body canal part has sub-vascular guidewire lumen.Conduit system also comprises female catheter balloons, and Bracket setting is on utricule.Female support is left in the proximal open that sub-conduit portion extends to female support by the wing passage of female support.

According to a method, mother lode pipe guide line inserts mother lode pipe until the distal end of mother lode pipe guide line passes the oral area of sub-vascular, and sub-vascular guide line inserts mother lode pipe until the distal end of sub-vascular guide line penetrates sub-vascular.In order to prevent guide line from intersecting, two vasculars are installed with the guide line conduit with two inner chambers to be separated to keep guide line and does not tangle.

Then remove guide line conduit and guide line separation member be placed on guide line to keep guide line not reel.Then conduit system is enclosed within mother lode pipe guide line and sub-vascular guide line and advances, and female Vascular catheters and sub-Vascular catheters are walked on mother lode pipe guide line and sub-vascular guide line.Conduit system is advanced on two guide lines, sub-vascular balloon catheter part in mother cyst body canal part distally, guidance system.When conduit system be enclosed within guide line is advanced time, sub-vascular utricule will enter sub-vascular and or can locate after placement mother lode pipe utricule simultaneously.Then the mother cyst body canal part of conduit system is distad advanced until can advance to the position stopped by knuckle.This mother cyst body canal part can not be traveled beyond bifurcation, because the pulling force of sub-conduit can prevent female conduit from distad moving on female support.Now, the distal part of female support exceedes the knuckle in mother lode pipe and can not advance further again.The method is convenient to conduit system and is advanced to furcation, and this may be necessary for coronary artery that is tortuous or calcification.Once conduit system is in place, sub-vascular balloon catheter part is just relative to female catheter pullback, thus the portions of proximal of ascus body is positioned partially in female support.Available radiopaque labelling is aimed at, and the proximal marker on two utricules is adjacent one another are.Then operator distad can touch conduit system, with to greatest extent with knuckle juxtaposition.Then to current portions the ascus body be positioned at below female support carry out inflation to guarantee the suitable aligning of female support.Ascus body also can have support on its distal part, and this can cause the portions of proximal of female support and submounts to be expanded simultaneously.Then antithetical phrase utricule is exitted.

Then inflation mother cyst body, this can make female support launch.If necessary or in order to mobile speckle carry out interface, the again inflation of two utricules.Removable conduit system while guide line is held in place.In this embodiment or in other embodiment any disclosed herein, angioplasty catheter makes vascular and pathological changes portion preexpanding before being used in placing rack.In certain embodiments, when adopting main support without the need to preexpanding with regard to when stent.If sometimes indicate preexpanding, then two vasculars may carry out angiopoiesis respectively.

In alternative method, female conduit can be arranged on sub-catheter guidewire, and sub-conduit can be arranged on female catheter guidewire.In the sub-vascular with high angle, such as when bifurcation angle is greater than about 60-70 °, compared with the constructed earlier being drawn into female support along side branch with submounts, the friction when operator needs to be drawn by submounts proximad along main split and draw in female support between conduit is lower.Conduit system is advanced, and makes ascus body canal guidance system also through the oral area of sub-vascular, remains in mother lode pipe simultaneously.When conduit system is advanced further, mother cyst body canal will enter sub-vascular.Conduit system can only to be advanced certain distance, until it is stopped by knuckle towards furcation.It can not be traveled beyond bifurcation, because the pulling force of sub-conduit can prevent female conduit from distad moving on female support.Now, the distal part of female support exceedes the oral area in mother lode pipe and can not advance further again.While female conduit is held in place, sub-conduit is pulled and the portions of proximal of ascus body is positioned partially in female support.Available radiopaque labelling is aimed at, and the proximal marker on two utricules is adjacent one another are.Then operator distad can touch conduit system, with to greatest extent with knuckle juxtaposition.Support (being positioned partially at now below female support) on ascus body is aimed at, and when making the inflation of group utricule, the nearly portion of submounts and female support expands simultaneously and fully covered by mother lode pipe.Then sub-vascular utricule is exitted.Then mother lode pipe utricule inflation, and the expansion of the distal part of female support.If needed, also interface procedure can be carried out.

If needed, the support that available any business is buied carries out stentplacement to mother lode pipe.Utricule on guide line can be used as the alternative form of sub-conduit.In alternative embodiments, conduit system can be arranged to ascus body and divides to divide nearside at mother cyst body and be enclosed within guide line and advance to furcation place.When female conduit is on female guide line, because the pulling force on sub-guide line and female conduit between female support prevents advancing further of female conduit, so female support is aimed at sub-vascular oral area.Under the alternative case of female conduit on sub-guide line, because the pulling force between female guide line and the upper female support support of female conduit (on sub-guide line) prevents advancing further of female conduit, so female support is aimed at mother lode spout part.In both cases, submounts advances to female rack alignment and expands.In the preferred embodiment, female conduit is the design being enclosed within (OTW) on guide line, and sub-conduit is quick exchange (RX) design, and sub-conduit portion is preferably at female catheter distal.Ascus body and then female conduit end distally place, this layout makes the general outline of conduit system minimum and allows at utmost to follow up tremulous pulse.This system also can have the support of pressing and being held on utricule.Submounts can have any length, but is about the half of ascus body or female stent length in the preferred embodiment.The proximal end of female support only slightly can be pressed and be held, and to allow sub-catheter balloons part independent operation, thus can carry out push-and-pull under not making female support offset ground situation.

Illustrative methods comprises the following steps:

1. make conduit system advance to furcation place, and ascus body canal part and mother cyst body canal part are in corresponding vascular.

2., due to the tension force between female support and sub-conduit, female conduit can not be advanced again.

3. ascus body portions of proximal to be pulled in female support and with radiopaque markers align.

4., while tightly gripping female conduit and sub-conduit, operator pushes away forward gently.

5. inflation ascus body submounts is expanded, the about half of ascus body distal part can make " half support " to expand, and the half in the nearly portion of ascus body can make the nearly portion of female support partly expand at mother lode pipe intramedullary expansion.The expansion of female nearly portion of support and submounts is preferably carried out simultaneously.

6. once submounts launches completely, then mother cyst body can be expanded to completely and be launched by female support distal part.

7. custom interface process can be used for guaranteeing complete juxtaposition.In a particular aspects, ascus body canal part can use without the need to support.This allows female support to aim at completely around the oral area of sub-vascular.Ascus is known from experience for aiming at as described in above-mentioned three steps, and makes the nearly portion expansion of female support.

In alternative embodiments, female conduit is the design being enclosed within (OTW) on guide line, and sub-conduit is quick exchange (RX) design, and sub-conduit portion is at female catheter distal.This system also can have the support of pressing and being held on utricule.Submounts is preferably less than the length of mother cyst body or support, but this does not represent restriction, and submounts can be any length.The proximal end of female support partly can be pressed and be held, and to allow sub-catheter balloons part independent operation, thus can not have restriction and rubs minimally to carry out push-and-pull, and do not block or affect female support.One illustrative methods comprises the following steps:

1. OTW is looped, thus operator can one hold two guide lines and then use another hand push two conduits.

2. make conduit system advance to furcation, and ascus body canal part and mother cyst body canal part are aimed at, as described in step 2 in above-described embodiment to 3 in corresponding vascular.

3. while tightly gripping female conduit and sub-conduit, conduit system is pushed away forward, until mother cyst body canal part stops at knuckle place.

4. inflation ascus body submounts is expanded, the about half of ascus body distal part can make " half support " to expand, and the half in the nearly portion of ascus body can make the nearly portion of female support partly expand at mother lode pipe intramedullary expansion.

5. once submounts launches completely, then mother cyst body can be expanded to completely and be launched by female support distal part.

6. custom interface process can be used for guaranteeing complete juxtaposition.

In a particular aspects, ascus body canal part can use without the need to support.This can allow female support to aim at completely around the oral area of sub-vascular.Ascus is known from experience for aiming at as described in above-mentioned three steps, and makes the nearly portion expansion of female support.

In alternative embodiments, female conduit is the design be enclosed within guide line, and sub-conduit exchanges design fast, and sub-conduit portion is at this female catheter distal.This system also can have the support of pressing and being held on utricule.Submounts is about the general of mother cyst body or stent length, but this does not represent restriction, and submounts can be any length.The proximal end of female support partly can be pressed and be held, and to allow sub-catheter balloons part independent operation, thus the skew of female support can not be made just to carry out push-and-pull.Illustrative methods comprises the following steps:

1. sub-conduit is arranged on the guide line in sub-vascular, and system is slipped into guide catheter and now mother cyst body is not arranged on guide line.Guiding sub-conduit enter coronary artery after and just before female conduit leaves guide catheter, female guide line be inserted through female conduit and enter mother lode pipe, then system being released guide catheter on two guide lines.The method alleviates coiling.

2. make conduit system advance to furcation place, and ascus body canal part and mother cyst body canal part are aimed in corresponding vascular.

3. make conduit system advance to furcation, and ascus body canal part and mother cyst body canal part are aimed at, as described in step 2 in above-described embodiment in corresponding vascular.Sub-conduit is retracted, until the proximal marker on two utricules is aimed at.

6. custom interface process can be used for guaranteeing complete juxtaposition.In a particular aspects, ascus body canal part can use without the need to support.This can allow female support to aim at completely around the oral area of sub-vascular.Ascus is known from experience for aiming at as described in above-mentioned three steps, and makes the nearly portion expansion of female support.

In alternative embodiments, mother system utricule and subsystem utricule are aimed at.This embodiment can comprise female support or submounts or arbitrary support.When existing female support has again submounts, submounts is preferably short than female support, but can be any length, and is about the half of female stent length in the preferred embodiment, thus submounts can be arranged in ascus body half portion far away.In addition, the nearly portion of sub-conduit axostylus axostyle is positioned at below female support that non-homogeneous pressure holds.Double bracket structure is reduced profile compared with covering the total length support of ascus body total length.

Method as herein described alternately comprises irrigating catheter and guide line port with the step of auxiliary operation.Method as herein described alternately comprises the attachment step of engaging coupling, and two conduits lock together by engaging coupling.In another particular aspects, each balloon catheter part can comprise at least one radiopaque labelling.Use this structure, the oral area of the passage of support with sub-vascular, to indicate balloon catheter part to pass oral area and ascus body canal part has penetrated sub-vascular, is therefore aimed at by the separation using fluoroscopy can observe labelling easily.In another particular aspects, the design of conduit system covers and exchanges fast and be enclosed within the combination on guide line; In order to observe object, mixed version is preferably, because they are more easily distinguished when using fluoroscopy.

In another particular aspects, nearside utricule can be expanded on difference ground, thus one end of utricule can be expanded prior to the other end.In another particular aspects, nearside balloon catheter part receivability can press down the support held to allow distally balloon catheter part freely-movable in transformation.

In another particular aspects, support can be pressed and be held in nearside balloon catheter part, and support can be designed to launch by variable profile to resist patient anatomy better.

In another particular aspects, distally balloon catheter part can via being pulled away from or peeling off capture duct to carry.All above-described embodiments can utilize the mother lode pipe holder with any diameter and the sub-vascular stent with any diameter, the diameter range of mother lode pipe holder preferably from about 2.5 to about 5 millimeters, and the diameter range of sub-vascular stent preferably from about 2 to about 5 millimeters.The length of support can be any length, and preferably scope is about 4 to about 40 millimeters.The position of conduit upper bracket is without the need to fixing and can be positioned on either one or two conduit.

catheter configurations:

Figure 1A illustrates the exemplary embodiment of conduit system 100, and above distally ascus body canal part comprises, pressure possesses the utricule of submounts.The comparable female support of submounts is short, and in this embodiment and other embodiment any of disclosing herein, this submounts can misalign on its corresponding utricule.Therefore, in the preferred embodiment, the nearly portion of ascus body keeps not covered by support, as hereafter by discussed in detail.In a specific embodiment, submounts is preferably the about half of female stent length.Distally submounts presses down in standard conditions known in the art and holds.Nearside mother cyst body canal part comprises mother cyst body and female support.Female support longitudinally with circumferential difference press and hold.In this exemplary embodiment, the half portion far away of female support presses down at representative condition holds, to guarantee that female support does not move during aiming at distally ascus body.In addition, the nearly portion of female support presses down in condition that is non-standard, pine relatively holds, even if thus a part for ascus body canal part is fenced by circumference, also permission distally ascus body canal part freely-movable.Female conduit and sub-conduit attached to each other slidably via hollow switching port.Switching port embeds in the side of the female conduit be enclosed within guide line, and has just enough large to allow the internal diameter of quick insertion recon conduit and utricule.Switching port can have any length extended between the nearly portion and the distal part of pipe joint element of utricule, and about 10 centimeter length in this embodiment, but in the preferred embodiment changing in the scope of about 1 centimetre to about 30 centimetres, and be that about 5cm to about 10cm is long in better embodiment.On switching port for the entrance of sub-conduit at nearside, and for the outlet of sub-conduit in the distal end of switching port.Sub-conduit is loaded by switching port, and ascus body distad extends from switching port outlet, preferably about 5 centimetres.But it is possible to, from any distance of mother cyst body, there is switching port, but preferably at mother cyst body nearside about 1 to about 30 centimetres.Submounts can be pressed and is held on utricule after utricule is loaded by switching port.Switching port preferably has tight fit to reduce conduit profile, and preferably has low friction and relative to each other slided by conduit easily to allow operator.

Figure 1B clearly show that each structure of conduit system 100 in Figure 1A.Stent delivery system 100 comprises the first conduit 102 and the second conduit 130.First conduit 102 comprises elongated axostylus axostyle 104, and being provided with near the distal end of elongated axostylus axostyle 104 can radial dilatation utricule 106.There is nearly portion 122, the support 108 of distal part 114 and side opening 120 is arranged on utricule 106.Distal part 114 pressure is held on utricule 106 and ejects during preventing conveying, and nearly portion 122 partly presses and is held on utricule 106, thus the second conduit 130 can be advanced slidably or retract below the nearly portion 122 of support 108.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 110 of elongated axostylus axostyle 104 distal end to elongated axostylus axostyle 104 extends to the guidewire lumen 112 had in the Y shape adapter 114 of connector 116.Connector 116 is preferably luer connector element, and this allows convenient to connect syringe or other rinses for inner chamber or the device of inject contrast.When not connecting, guidewire lumen 112 is drawn via connector 116.Second connector 118 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 106 in elongated axostylus axostyle 104.First conduit 102 also comprises the hollow switching port pipe 124 being connected in elongated axostylus axostyle 104.Hollow switching port pipe 124 jointly can extrude with the first axostylus axostyle 104 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Hollow switching port alternately connects with another axostylus axostyle 132.Hollow switching port pipe 124 comprises the central passage 126 that extends through wherein and size makes a part of receiving the second conduit 130 slidably.Radiopaque labelling can be placed on diverse location along axostylus axostyle 104, usually near utricule 106 and/or support 108, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 130 comprises elongated axostylus axostyle 132, and being provided with near the distal end of elongated axostylus axostyle 132 can radial dilatation utricule 140.Support 142 is arranged on utricule 140.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 142 is shorter than the active length of utricule 140, thus the nearly portion of utricule 140 is by the constraint of support 142, and this of utricule 140 is unfettered partially passes through side opening 120 and advance slidably below the nearly portion 122 of support 108 or retract, and this will hereinafter be described.Support 142 pressure is held on utricule 140 and ejects during preventing conveying.Utricule 140 distad offset to make the profile of device minimum relative to utricule 106 and support 108 with support 142 at least partially.In this embodiment, distal stent 142 can be launched in the main split of vascular, and another support 108 can launch in the side branch of vascular.Or distal stent 142 can be launched in the side branch of vascular, and another support 108 can launch in the main split of vascular.Second conduit 130 is the rapid-exchange catheter (RX) with guidewire lumen 134, guidewire lumen 134 extends to nearside guide line port one 36 from the distal guide line cap 138 of elongated axostylus axostyle 132 distal end, nearside guide line port one 36 than the proximal end of conduit axostylus axostyle 132 closer to distal port 138.Nearside guide line port one 36 also not to hinder and preferably at its nearside by hollow exchanging tube 124.Preferably for the connector 144 of luer connector element is connected to the proximal end of elongated axostylus axostyle 132, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 132 with inflation utricule 140.A part for axostylus axostyle 132 is arranged in the central passage 126 of hollow exchanging tube 124, and this contributes to keeping two conduit axostylus axostyles 104,132 parallel and prevent from tangling during carrying and when axostylus axostyle 132 is advanced slidably relative to axostylus axostyle 104 or retracts.In addition, another part of axostylus axostyle 132 is arranged on below the nearly portion 122 of support 108.Second conduit 130 also can be advanced slidably or retract below the nearly portion 122 of support 108, makes axostylus axostyle 132 through the side opening 120 in support 108.Radiopaque labelling can be placed on diverse location on axostylus axostyle 132, usually near utricule 140 or support 142, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 2 A illustrates the sectional view of an embodiment of conduit system 200, and this conduit system uses the identical switching port shown in Figure 1A, and its neutron catheter balloons part is positioned at mother cyst body point distally.Mother cyst body preferably from the outlet distally of switching port at least about 5 centimetres.As mentioned above, mother cyst body can be about 1cm to about 30 centimetres from switching port distally.

Fig. 2 B clearly show that each structure of conduit system 200 in Fig. 2 A.Stent delivery system 200 comprises the first conduit 202 and the second conduit 230.First conduit 202 comprises elongated axostylus axostyle 204, and being provided with near the distal end of elongated axostylus axostyle 204 can radial dilatation utricule 206, and utricule 206 is provided with support 208.Support 208 can have the length identical with the active length of utricule 208, or support can be shorter.In the preferred embodiment, support 208 is shorter than the active length of utricule 206, makes the nearly portion of utricule 206 keep not limiting by support 208.Can advance slidably via side opening 220 and retract in the nearly portion of utricule 206 below support 242.Support 208 pressure is held utricule 206 and is ejected during preventing conveying.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 210 of elongated axostylus axostyle 204 distal end to elongated axostylus axostyle 204 extends to the guidewire lumen 212 had in the Y shape adapter 214 of connector 216.Connector 216 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out inner chamber flushing or inject contrast device.When not connecting, guidewire lumen 212 is drawn via connector 216.Second connector 218 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 206 in elongated axostylus axostyle 204.First conduit 202 also comprises the hollow switching port pipe 224 being connected to elongated axostylus axostyle 204.Hollow switching port pipe 224 jointly can extrude with the first axostylus axostyle 204 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Hollow switching port alternately connects with another axostylus axostyle 232.Hollow switching port pipe 224 comprises the central passage 226 that extends through wherein and size makes a part of receiving the second conduit 230 slidably.Radiopaque labelling can be placed on diverse location along axostylus axostyle 204, usually near utricule 206 and/or support 208, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 230 comprises elongated axostylus axostyle 232, and being provided with near the distal end of elongated axostylus axostyle 232 can radial dilatation utricule 240.There is nearly portion 222, the support 242 of distal part 214 and side opening 220 is arranged on utricule 240.Distal part 214 pressure is held utricule 240 and is ejected during preventing conveying, and nearly portion 222 partly presses and holds utricule 240, makes elongated axostylus axostyle 204 to advance slidably below the nearly portion 222 of support 242 or to retract.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Utricule 206 distad offset to make the profile of device minimum relative to utricule 240 and support 242 with support 208 at least partially.In this embodiment, distal stent 208 can be launched in the main split of vascular, and another support 242 can launch in the side branch of vascular.Or distal stent 208 can be launched in the side branch of vascular, and another support 242 can launch in the main split of vascular.Second conduit 230 is the rapid-exchange catheter (RX) with guidewire lumen 234, guidewire lumen 234 extends to nearside guide line port 236 from the distal guide line cap 238 of elongated axostylus axostyle 232 distal end, nearside guide line port 236 than the proximal end of conduit axostylus axostyle 232 closer to distal port 238.Nearside guide line port 236 also not to hinder and preferably at its nearside by hollow exchanging tube 224.Preferably for the connector 244 of luer connector element is connected to the proximal end of elongated axostylus axostyle 232, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 232 with inflation utricule 240.A part for axostylus axostyle 232 is arranged in the central passage 226 of hollow exchanging tube 224, and this contributes to keeping two conduit axostylus axostyles 204,232 parallel and prevent from tangling during carrying and when axostylus axostyle 232 goes forward one by one slidably relative to axostylus axostyle 204 or retracts.In addition, a part for axostylus axostyle 204 is arranged on below the nearly portion 222 of support 242.First conduit 202 also can be advanced slidably or retract below the nearly portion 222 of support 242, makes axostylus axostyle 204 through the side opening 220 in support 242.Radiopaque labelling can be placed on diverse location on axostylus axostyle 232, usually near utricule 240 or support 242, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 3 A illustrates the sectional view of an embodiment of conduit system 300, and female conduit and sub-conduit all have and exchange design fast.In this particular example, one in conduit has the hollow switching port be embedded in its side, and another conduit is loaded by this switching port.Usually, before support pressure is held in utricule part, conduit is loaded.

Fig. 3 B clearly show that the feature of conduit system 300 in Fig. 3 A.Induction system 300 comprises the first conduit 302 and the second conduit 330.First conduit 302 comprises elongated axostylus axostyle 304, and being provided with near the distal end of elongated axostylus axostyle 304 can radial dilatation utricule 306.There is nearly portion 322, the support 308 of distal part 314 and side opening 320 is arranged on utricule 306.Distal part 314 pressure is held utricule 306 and is ejected during preventing conveying, and nearly portion 322 partly presses and holds utricule 306, thus the second conduit 330 can be advanced in nearly portion 322 slid underneath of support 308.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 312, guidewire lumen 312 extends to nearside guide line port 311 from the distal guide line cap 310 of elongated axostylus axostyle 304 distal end, nearside guide line port 311 than the proximal end of conduit axostylus axostyle 304 closer to distal port 310.Connector 316 connects with the proximal end of elongated axostylus axostyle 304.Connector 316 is preferably luer connector element, and this permission connects with decompressor or other device with inflation utricule 306 easily.First conduit 302 also comprises the hollow switching port pipe 324 being connected to elongated axostylus axostyle 304.Hollow switching port pipe 324 jointly can extrude with the first axostylus axostyle 304 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Hollow switching port alternately connects with another axostylus axostyle 332.Hollow switching port pipe 324 comprises the central passage 326 that extends through wherein and size makes a part of receiving the second conduit 330 slidably.Radiopaque labelling can be placed on diverse location along axostylus axostyle 304, usually near utricule 306 and/or support 308, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 330 comprises elongated axostylus axostyle 332, and being provided with near the distal end of elongated axostylus axostyle 332 can radial dilatation utricule 340.Support 342 is arranged on utricule 340.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 342 is shorter than the active length of utricule 340, thus the nearly portion of utricule 340 is by the constraint of support 342, and this of utricule 340 is unfettered partially passes through side opening 320 and advance slidably below the nearly portion 322 of support 308 or retract, and this will hereinafter be described.Support 342 pressure is held utricule 340 and is ejected during preventing conveying.Utricule 340 distad offset to make the profile of device minimum relative to utricule 306 and support 308 with support 342 at least partially.In this embodiment, distal stent 342 can be launched in the main split of vascular, and another support 308 can launch in the side branch of vascular.Or distal stent 342 can be launched in the side branch of vascular, and another support 308 can launch in the main split of vascular.Second conduit 330 is the rapid-exchange catheter (RX) with guidewire lumen 334, guidewire lumen 334 extends to nearside guide line port 336 from the distal guide line cap 338 of elongated axostylus axostyle 332 distal end, nearside guide line port 336 than the proximal end of conduit axostylus axostyle 332 closer to distal port 338.Nearside guide line port 336 does not also hinder by hollow exchanging tube 324 and can in its distally.Preferably for the connector 344 of luer connector element is connected to the proximal end of elongated axostylus axostyle 332, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 332 with inflation utricule 340.A part for axostylus axostyle 332 is arranged in the central passage 326 of hollow exchanging tube 324, and this contributes to keeping two conduit axostylus axostyles 304,332 parallel and prevent from tangling during carrying and when axostylus axostyle 332 is advanced slidably relative to axostylus axostyle 304 or retracts.In addition, another part of axostylus axostyle 332 is arranged on below the nearly portion 322 of support 308.Second conduit 330 also can be advanced slidably or retract below the nearly portion 322 of support 308, thus axostylus axostyle 332 is through the side opening 320 in support 308.Radiopaque labelling can be placed on diverse location on axostylus axostyle 332, usually near utricule 340 or support 342, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 4 A illustrates the sectional view of an embodiment of conduit system 400, and female conduit and sub-conduit all have the design be enclosed within guide line.In this particular example, one in conduit has the hollow switching port be embedded in its side, and another conduit does not have hollow switching port.The catheter cartridge without switching port is downloaded to and has on the conduit of switching port.Usually, conduit must be loaded before support pressure is held in utricule part.

Fig. 4 B clearly show that the feature of conduit system 400 in Fig. 4 A.Stent delivery system 400 comprises the first conduit 402 and the second conduit 430.First conduit 402 comprises elongated axostylus axostyle 404, and being provided with near the distal end of elongated axostylus axostyle 404 can radial dilatation utricule 406.There is nearly portion 422, the support 408 of distal part 414 and side opening 420 is arranged on utricule 406.Distal part 414 pressure is held utricule 406 and is ejected during preventing conveying, and nearly portion 422 partly presses and holds utricule 406, thus the second conduit 430 can be advanced in nearly portion 422 slid underneath of support 408.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 410 of elongated axostylus axostyle 404 distal end to elongated axostylus axostyle 404 extends to the guidewire lumen 412 of the Y shape adapter 414 with connector 416.Connector 416 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 412 is drawn via connector 416.Second connector 418 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 406 in elongated axostylus axostyle 404.First conduit 402 also comprises the hollow switching port pipe 424 being connected to elongated axostylus axostyle 404.Hollow switching port pipe 424 jointly can extrude with the first axostylus axostyle 404 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Hollow switching port alternately connects with another axostylus axostyle 432.Hollow switching port pipe 424 comprises the central passage 426 that extends through wherein and size makes a part of receiving the second conduit 430 slidably.Radiopaque labelling can be placed on diverse location along axostylus axostyle 404, usually near utricule 406 and/or support 408, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 430 comprises elongated axostylus axostyle 432, and being provided with near the distal end of elongated axostylus axostyle 432 can radial dilatation utricule 440.Support 442 is arranged on utricule 440.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 442 is shorter than the active length of utricule 440, thus the nearly portion of utricule 440 is by the constraint of support 442, and this of utricule 440 is unfettered partially passes through side opening 420 and advance slidably below the nearly portion 422 of support 408 or retract, and this will hereinafter be described.Support 442 pressure is held utricule 440 and is ejected during preventing conveying.Utricule 440 distad offset to make the profile of device minimum relative to utricule 406 and support 408 with support 442 at least partially.In this embodiment, distal stent 442 can be launched in the main split of vascular, and another support 408 can launch in the side branch of vascular.Or distal stent 442 can be launched in the side branch of vascular, and another support 408 can launch in the main split of vascular.Second conduit 430 is the conduits being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 438 of elongated axostylus axostyle 432 distal end to elongated axostylus axostyle 432 extends to the guidewire lumen 434 had in the Y shape adapter 446 of connector 448.Connector 448 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 434 is drawn via connector 448.Second connector 444 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 440 in elongated axostylus axostyle 432.A part for axostylus axostyle 432 is arranged in the central passage 424 of hollow exchanging tube 426, and this contributes to keeping two conduit axostylus axostyles 404,432 parallel and prevent from tangling during carrying and when axostylus axostyle 432 is advanced slidably relative to axostylus axostyle 404 or retracts.In addition, another part of axostylus axostyle 432 is arranged on below the nearly portion 422 of support 408.Second conduit 430 also can be advanced slidably or retract below the nearly portion 422 of support 408, thus axostylus axostyle 432 is through the side opening 420 in support 408.Radiopaque labelling can be placed on diverse location on axostylus axostyle 432, usually near utricule 440 or support 442, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 5 A, 6A, 7A and 8A illustrate the end-to-end capture duct together with tubes connection.Capture duct prevents conduit from tangling.Capture duct is preferably held in place in whole clinical course.In these exemplary embodiments, capture duct is thin polymer hollow bar, and the position that this hollow bar is about 10 centimetres from the attached distally of decompressor covers female conduit and sub-conduit to the distalis of the nearside rapid-exchange port nearside about 10 centimetres of rapid-exchange catheter.

Fig. 5 A illustrates conduit system 500, comprises the sub-conduit in distally with exchange structure fast and is enclosed within the female conduit of the nearside that guide line constructs with having.Fig. 5 B clearly show that the feature of conduit system 500 in Fig. 5 A.Stent delivery system 500 comprises the first conduit 502 and the second conduit 530.First conduit 502 comprises elongated axostylus axostyle 504, and being provided with near the distal end of elongated axostylus axostyle 504 can radial dilatation utricule 506.There is nearly portion 522, the support 508 of distal part 514 and side opening 520 is arranged on utricule 506.Distal part 514 pressure is held utricule 506 and is ejected during preventing conveying, and nearly portion 522 partly presses and holds utricule 506, thus the second conduit 530 can be advanced in nearly portion 522 slid underneath of support 508.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 510 of elongated axostylus axostyle 504 distal end to elongated axostylus axostyle 504 extends to the guidewire lumen 512 of the Y shape adapter 514 with connector 516.Connector 516 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 512 is drawn via connector 516.Second connector 518 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 506 in elongated axostylus axostyle 504.First conduit 502 is arranged in the central passage 526 of capture duct 524.Central passage 526 size is made adaptive with axostylus axostyle 504,532 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 504 can slide in central passage 526, or the lock ring 525 of its available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 504, usually near utricule 506 and/or support 508, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 530 comprises elongated axostylus axostyle 532, and being provided with near the distal end of elongated axostylus axostyle 532 can radial dilatation utricule 540.Support 542 is arranged on utricule 540.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 542 is shorter than the active length of utricule 540, thus the nearly portion of utricule 540 is by the constraint of support 542, and this of utricule 540 is unfettered partially passes through side opening 520 and advance slidably below the nearly portion 522 of support 508 or retract, and this will hereinafter be described.Support 542 pressure is held utricule 540 and is ejected during preventing conveying.Utricule 540 distad offset to make the profile of device minimum relative to utricule 506 and support 508 with support 542 at least partially.In this embodiment, distal stent 542 can be launched in the main split of vascular, and another support 508 can launch in the side branch of vascular.Or distal stent 542 can be launched in the side branch of vascular, and another support 508 can launch in the main split of vascular.Second conduit 530 is the rapid-exchange catheter (RX) with guidewire lumen 534, guidewire lumen 534 extends to nearside guide line port 536 from the distal guide line cap 538 of elongated axostylus axostyle 532 distal end, nearside guide line port 536 than the proximal end of conduit axostylus axostyle 532 closer to distal port 538.Nearside guide line port 536 does not also hinder by capture duct 524 and can in its distally.Preferably for the connector 544 of luer connector element is connected to the proximal end of elongated axostylus axostyle 532, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 532 with inflation utricule 540.A part for axostylus axostyle 532 is arranged in the central passage 526 of capture duct 524, and this contributes to keeping two conduit axostylus axostyles 504,532 parallel and prevent from tangling during carrying and when axostylus axostyle 532 is advanced slidably in central passage 526.Compression fitting 525 can be used for being locked in by elongated axostylus axostyle 504,532 in capture duct 524 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, another part of axostylus axostyle 532 is arranged on below the nearly portion 522 of support 508.Second conduit 530 also can be advanced slidably or retract below the nearly portion 522 of support 508, thus axostylus axostyle 532 is through the side opening 520 in support 508.Radiopaque labelling can be placed on diverse location on axostylus axostyle 532, usually near utricule 540 or support 542, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 6 A illustrates conduit system 600, comprises having being enclosed within the sub-conduit in the distally that guide line designs and having the female conduit of the nearside exchanging design fast.Fig. 6 B clearly show that the feature of conduit system 600 in Fig. 6 A.Stent delivery system 600 comprises the first conduit 602 and the second conduit 630.First conduit 602 comprises elongated axostylus axostyle 604, and being provided with near the distal end of elongated axostylus axostyle 604 can radial dilatation utricule 606, and utricule 606 is provided with support 608.Support 608 can have the length identical with the active length of utricule 608, or it can be shorter.In the preferred embodiment, support 608 is shorter than the active length of utricule 606, makes the nearly portion of utricule 606 keep not limiting by support 608.Can advance slidably via side opening 620 and retract in the nearly portion of utricule 606 below support 642.Support 608 pressure is held utricule 606 and is ejected during preventing conveying.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 610 of elongated axostylus axostyle 604 distal end to elongated axostylus axostyle 604 extends to the guidewire lumen 612 of the Y shape adapter 614 with connector 616.Connector 616 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 612 is drawn via connector 616.Second connector 618 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 606 in elongated axostylus axostyle 604.First conduit 602 is arranged in the central passage 626 of capture duct 624.Central passage 626 size is made adaptive with axostylus axostyle 604,632 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 604 can slide in central passage 626, or the lock ring 625 of available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 604, usually near utricule 606 and/or support 608, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 630 comprises elongated axostylus axostyle 632, and being provided with near the distal end of elongated axostylus axostyle 632 can radial dilatation utricule 640.There is nearly portion 622, the support 642 of distal part 614 and side opening 620 is arranged on utricule 640.Distal part 614 pressure is held utricule 640 and is ejected during preventing conveying, and nearly portion 622 partly presses and holds utricule 640, thus elongated axostylus axostyle 604 can be advanced slidably or retract below the nearly portion 622 of support 642.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Utricule 606 distad offset to make the profile of device minimum relative to utricule 640 and support 642 with support 608 at least partially.In this embodiment, distal stent 608 can be launched in the main split of vascular, and another support 642 can launch in the side branch of vascular.Or distal stent 608 can be launched in the side branch of vascular, and another support 642 can launch in the main split of vascular.Second conduit 630 is the rapid-exchange catheter (RX) with guidewire lumen 634, guidewire lumen 634 extends to nearside guide line port 636 from the distal guide line cap 638 of elongated axostylus axostyle 632 distal end, nearside guide line port 636 than the proximal end of conduit axostylus axostyle 632 closer to distal port 638.Nearside guide line port 636 does not also hinder by capture duct 624 and can in its distally.Preferably for the connector 644 of luer connector element is connected to the proximal end of elongated axostylus axostyle 632, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 632 with inflation utricule 640.A part for axostylus axostyle 632 is arranged in the central passage 626 of capture duct 624, and this contributes to keeping two conduit axostylus axostyles 604,632 parallel and prevent from tangling during carrying and when axostylus axostyle 604 is advanced slidably in central passage 626.Compression fitting 625 can be used for being locked in by elongated axostylus axostyle 604,632 in capture duct 624 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, a part for axostylus axostyle 604 is arranged on below the nearly portion 622 of support 642.First conduit 602 also can be advanced slidably or retract below the nearly portion 622 of support 642, thus axostylus axostyle 604 is through the side opening 620 in support 642.Radiopaque labelling can be placed on diverse location on axostylus axostyle 632, usually near utricule 640 or support 642, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 7 A illustrates conduit system 700, comprises double quick speed and exchanges female conduit and sub-conduit, thus the end points of capture duct preferably rapid-exchange port nearside about 10 centimeters on farthest side conduit.Fig. 7 B clearly show that the feature of conduit system 700 in Fig. 7 A.Stent delivery system 700 comprises the first conduit 702 and the second conduit 730.First conduit 702 comprises elongated axostylus axostyle 704, and being provided with near the distal end of elongated axostylus axostyle 704 can radial dilatation utricule 706.There is nearly portion 722, the support 708 of distal part 714 and side opening 720 is arranged on utricule 706.Distal part 714 pressure is held utricule 706 and is ejected during preventing conveying, and nearly portion 722 partly presses and holds utricule 706, thus the second conduit 730 can be advanced in nearly portion 722 slid underneath of support 708.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 712, guidewire lumen 712 extends to nearside guide line port 711 from the distal guide line cap 710 of elongated axostylus axostyle 704 distal end, nearside guide line port 711 than the proximal end of conduit axostylus axostyle 704 closer to distal port 710.Connector 716 connects with the proximal end of elongated axostylus axostyle 704.Connector 716 is preferably luer connector element, and this permission connects with decompressor or other device with inflation utricule 706 easily.First conduit 702 is arranged in the central passage 726 of capture duct 724.Central passage 726 size is made adaptive with axostylus axostyle 704,732 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 704 can slide in central passage 726, or the lock ring 725 of available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 704, usually near utricule 706 and/or support 708, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 730 comprises elongated axostylus axostyle 732, and being provided with near the distal end of elongated axostylus axostyle 732 can radial dilatation utricule 740.Support 742 is arranged on utricule 740.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 742 is shorter than the active length of utricule 740, thus the nearly portion of utricule 740 is by the constraint of support 742, and this of utricule 740 is unfettered partially passes through side opening 720 and advance slidably below the nearly portion 722 of support 708 or retract, and this will hereinafter be described.Support 742 pressure is held utricule 740 and is ejected during preventing conveying.Utricule 740 distad offset to make the profile of device minimum relative to utricule 706 and support 708 with support 742 at least partially.In this embodiment, distal stent 742 can be launched in the main split of vascular, and another support 708 can launch in the side branch of vascular.Or distal stent 742 can be launched in the side branch of vascular, and another support 708 can launch in the main split of vascular.Second conduit 730 is the rapid-exchange catheter (RX) with guidewire lumen 734, guidewire lumen 734 extends to nearside guide line port 736 from the distal guide line cap 738 of elongated axostylus axostyle 732 distal end, nearside guide line port 736 than the proximal end of conduit axostylus axostyle 732 closer to distal port 738.Nearside guide line port 736 does not also hinder by capture duct 724 and can in its distally.Preferably for the connector 744 of luer connector element is connected to the proximal end of elongated axostylus axostyle 732, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 732 with inflation utricule 740.A part for axostylus axostyle 732 is arranged in the central passage 726 of capture duct 724, and this contributes to keeping two conduit axostylus axostyles 704,732 parallel and prevent from tangling during carrying and when axostylus axostyle 732 is advanced slidably in central passage 726.Compression fitting 725 can be used for being locked in by elongated axostylus axostyle 704,732 in capture duct 724 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, another part of axostylus axostyle 732 is arranged on below the nearly portion 722 of support 708.Second conduit 730 also can be advanced slidably or retract below the nearly portion 722 of support 708, thus axostylus axostyle 732 is through the side opening 720 in support 708.Radiopaque labelling can be placed on diverse location on axostylus axostyle 732, usually near utricule 740 or support 742, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 8 A illustrates to have and two is enclosed within the conduit system 800 that guide line designs, and therefore capture duct end points preferably terminates in from farthest side catheter balloons part nearside about 30 centimeters.Fig. 8 B clearly show that the feature of conduit system 800 in Fig. 8 A.Stent delivery system 800 comprises the first conduit 802 and the second conduit 830.First conduit 802 comprises elongated axostylus axostyle 804, and being provided with near the distal end of elongated axostylus axostyle 804 can radial dilatation utricule 806.There is nearly portion 822, the support 808 of distal part 814 and side opening 820 is arranged on utricule 806.Distal part 814 pressure is held utricule 806 and is ejected during preventing conveying, and nearly portion 822 partly presses and holds utricule 806, thus the second conduit 830 can be advanced in nearly portion 822 slid underneath of support 808.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 810 of elongated axostylus axostyle 804 distal end to elongated axostylus axostyle 804 extends to the guidewire lumen 812 of the Y shape adapter 814 with connector 816.Connector 816 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 812 is drawn via connector 816.Second connector 818 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 806 in elongated axostylus axostyle 804.First conduit 802 is arranged in the central passage 826 of capture duct 824.Central passage 826 size is made adaptive with axostylus axostyle 804,832 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 804 can slide in central passage 826, or the lock ring 825 of its available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 804, usually near utricule 806 and/or support 808, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 830 comprises elongated axostylus axostyle 832, and being provided with near the distal end of elongated axostylus axostyle 832 can radial dilatation utricule 840.Support 842 is arranged on utricule 840.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 842 is shorter than the active length of utricule 840, thus the nearly portion of utricule 840 is by the constraint of support 842, and this of utricule 840 is unfettered partially passes through side opening 820 and advance slidably below the nearly portion 822 of support 808 or retract, and this will hereinafter be described.Support 842 pressure is held utricule 840 and is ejected during preventing conveying.Utricule 840 distad offset to make the profile of device minimum relative to utricule 806 and support 808 with support 842 at least partially.In this embodiment, distal stent 842 can be launched in the main split of vascular, and another support 808 can launch in the side branch of vascular.Or distal stent 842 can be launched in the side branch of vascular, and another support 808 can launch in the main split of vascular.Second conduit 830 is the conduits being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 838 of elongated axostylus axostyle 832 distal end to elongated axostylus axostyle 832 extends to the guidewire lumen 834 of the Y shape adapter 846 with connector 848.Connector 848 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 834 is drawn via connector 848.Second connector 844 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 840 in elongated axostylus axostyle 832.A part for axostylus axostyle 832 is arranged in the central passage 826 of capture duct 824, and this contributes to keeping two conduit axostylus axostyles 804,832 parallel and prevent from tangling during carrying and when axostylus axostyle 832 is advanced slidably in central passage 826.Compression fitting 825 can be used for being locked in by elongated axostylus axostyle 804,832 in capture duct 824 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, another part of axostylus axostyle 832 is arranged on below the nearly portion 822 of support 808.Second conduit 830 also can be advanced slidably or retract below the nearly portion 822 of support 808, thus axostylus axostyle 832 is through the side opening 820 in support 808.Radiopaque labelling can be placed on diverse location on axostylus axostyle 832, usually near utricule 840 or support 842, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Fig. 9 A, 10A, 11A and 12A illustrate the detachable capture duct overlapping and fit on above-mentioned DLC, but this capture duct has polymer adnexa.Once conduit system is placed near furcation by operator, then operator can grasp polymer adnexa and be drawn from conduit by capture duct and remove.

Fig. 9 A illustrates conduit system 900, comprises the sub-conduit in distally with exchange structure fast and is enclosed within the female conduit of the nearside that guide line constructs with having.Fig. 9 B clearly show that the feature of conduit system 900 in Fig. 9 A.Stent delivery system 900 comprises the first conduit 902 and the second conduit 930.First conduit 902 comprises elongated axostylus axostyle 904, and being provided with near the distal end of elongated axostylus axostyle 904 can radial dilatation utricule 906.There is nearly portion 922, the support 908 of distal part 914 and side opening 920 is arranged on utricule 906.Distal part 914 pressure is held utricule 906 and is ejected during preventing conveying, and nearly portion 922 partly presses and holds utricule 906, thus the second conduit 930 can be advanced in nearly portion 922 slid underneath of support 908.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 910 of elongated axostylus axostyle 904 distal end to elongated axostylus axostyle 904 extends to the guidewire lumen 912 of the Y shape adapter 914 with connector 916.Connector 916 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 912 is drawn via connector 916.Second connector 918 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 906 in elongated axostylus axostyle 904.First conduit 902 is arranged in the central passage 926 of capture duct 924, and this central passage has punched areas 945 along its longitudinal length.Central passage 926 size is made adaptive with axostylus axostyle 904,932 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 904 can slide in central passage 926, or the lock ring 925 of its available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 904, usually near utricule 906 and/or support 908, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.Suitably located once conduit and no longer needed, the punched areas 945 along capture duct 924 allows capture duct to peel off easily from two conduit axostylus axostyles 904,932.

Second conduit 930 comprises elongated axostylus axostyle 932, and being provided with near the distal end of elongated axostylus axostyle 932 can radial dilatation utricule 940.Support 942 is arranged on utricule 940.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 942 is shorter than the active length of utricule 940, thus the nearly portion of utricule 940 is by the constraint of support 942, and this of utricule 940 is unfettered partially passes through side opening 920 and advance slidably below the nearly portion 922 of support 908 or retract, and this will hereinafter be described.Support 942 pressure is held utricule 940 and is ejected during preventing conveying.Utricule 940 distad offset to make the profile of device minimum relative to utricule 906 and support 908 with support 942 at least partially.In this embodiment, distal stent 942 can be launched in the main split of vascular, and another support 908 can launch in the side branch of vascular.Or distal stent 942 can be launched in the side branch of vascular, and another support 908 can launch in the main split of vascular.Second conduit 930 is the rapid-exchange catheter (RX) with guidewire lumen 934, guidewire lumen 934 extends to nearside guide line port 936 from the distal guide line cap 938 of elongated axostylus axostyle 932 distal end, nearside guide line port 936 than the proximal end of conduit axostylus axostyle 932 closer to distal port 938.Nearside guide line port 936 does not also hinder by capture duct 924 and can in its distally.Preferably for the connector 944 of luer connector element is connected to the proximal end of elongated axostylus axostyle 932, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 932 with inflation utricule 940.A part for axostylus axostyle 932 is arranged in the central passage 926 of capture duct 924, and this contributes to keeping two conduit axostylus axostyles 904,932 parallel and prevent from tangling during carrying and when axostylus axostyle 932 is advanced slidably in central passage 926.Compression fitting 925 can be used for being locked in by elongated axostylus axostyle 904,932 in capture duct 924 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, another part of axostylus axostyle 932 is arranged on below the nearly portion 922 of support 908.Second conduit 930 also can be advanced slidably or retract below the nearly portion 922 of support 908, thus axostylus axostyle 932 is through the side opening 920 in support 908.Capture duct 924 is peeled off from axostylus axostyle 932 by breaking punched areas 945.Radiopaque labelling can be placed on diverse location on axostylus axostyle 932, usually near utricule 940 or support 942, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 10 A illustrates conduit system 1000, comprises having being enclosed within the sub-conduit in the distally that guide line designs and having the female conduit of the nearside exchanging design fast.Figure 10 B clearly show that the feature of conduit system 1000 in Figure 10 A.Stent delivery system 1000 comprises the first conduit 1002 and the second conduit 1030.First conduit 1002 comprises elongated axostylus axostyle 1004, and being provided with near the distal end of elongated axostylus axostyle 1004 can radial dilatation utricule 1006, and utricule 1006 is provided with support 1008.Support 1008 can have the length identical with the active length of utricule 1008, or it can be shorter.In the preferred embodiment, support 1008 is shorter than the active length of utricule 1006, makes the nearly portion of utricule 1006 keep not limiting by support 1008.Can advance slidably via side opening 1020 and retract in the nearly portion of utricule 1006 below support 1042.Support 1008 pressure is held utricule 1006 and is ejected during preventing conveying.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1010 of elongated axostylus axostyle 1004 distal end to elongated axostylus axostyle 1004 extends to the guidewire lumen 1012 of the Y shape adapter 1014 with connector 1016.Connector 1016 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1012 is drawn via connector 1016.Second connector 1018 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1006 in elongated axostylus axostyle 1004.First conduit 1002 is arranged in the central passage 1026 of capture duct 1024, and this central area has punched areas 1045.Central passage 1026 size is made adaptive with axostylus axostyle 1004,1032 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 1004 can slide in central passage 1026, or the lock ring 1025 of its available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1004, usually near utricule 1006 and/or support 1008, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.Suitably located once conduit and no longer needed, the punched areas 1045 along capture duct 1024 allows capture duct to peel off easily from two conduit axostylus axostyles 1004,1032.

Second conduit 1030 comprises elongated axostylus axostyle 1032, and being provided with near the distal end of elongated axostylus axostyle 1032 can radial dilatation utricule 1040.There is nearly portion 1022, the support 1042 of distal part 1014 and side opening 1020 is arranged on utricule 1040.Distal part 1014 pressure is held utricule 1040 and is ejected during preventing conveying, and nearly portion 1022 partly presses and holds utricule 1040, thus elongated axostylus axostyle 1004 can be advanced slidably or retract below the nearly portion 1022 of support 1042.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Utricule 1006 distad offset to make the profile of device minimum relative to utricule 1040 and support 1042 with support 1008 at least partially.In this embodiment, distal stent 1008 can be launched in the main split of vascular, and another support 1042 can launch in the side branch of vascular.Or distal stent 1008 can be launched in the side branch of vascular, and another support 1042 can launch in the main split of vascular.Second conduit 1030 is the rapid-exchange catheter (RX) with guidewire lumen 1034, guidewire lumen 1034 extends to nearside guide line port one 036 from the distal guide line cap 1038 of elongated axostylus axostyle 1032 distal end, nearside guide line port one 036 than the proximal end of conduit axostylus axostyle 1032 closer to distal port 1038.Nearside guide line port one 036 does not also hinder by capture duct 1024 and can in its distally.Preferably for the connector 1044 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1032, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1032 with inflation utricule 1040.A part for axostylus axostyle 1032 is arranged in the central passage 1026 of capture duct 1024, and this contributes to keeping two conduit axostylus axostyles 1004,1032 parallel and prevent from tangling during carrying and when axostylus axostyle 1032 is advanced slidably in central passage 1026.Compression fitting 1025 can be used for being locked in by elongated axostylus axostyle 1004,1032 in capture duct 1024 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, a part for axostylus axostyle 1004 is arranged on below the nearly portion 1022 of support 1042.First conduit 1002 also can be advanced slidably or retract below the nearly portion 1022 of support 1042, thus axostylus axostyle 1004 is through the side opening 1020 in support 1042.Capture duct 1024 is peeled off from axostylus axostyle 1032 by breaking punched areas 1045.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1032, usually near utricule 1040 or support 1042, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 11 A illustrates conduit system 1100, and the double quick speed comprised with detachable capture duct exchanges design.Figure 11 B clearly show that the feature of conduit system 1100 in Figure 11 A.Stent delivery system 1100 comprises the first conduit 1102 and the second conduit 1130.First conduit 1102 comprises elongated axostylus axostyle 1104, and being provided with near the distal end of elongated axostylus axostyle 1104 can radial dilatation utricule 1106.There is nearly portion 1122, the support 1108 of distal part 1114 and side opening 1120 is arranged on utricule 1106.Distal part 1114 pressure is held utricule 1106 and is ejected during preventing conveying, and nearly portion 1122 partly presses and holds utricule 1106, thus the second conduit 1130 can be advanced in nearly portion 1122 slid underneath of support 1108.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 1112, guidewire lumen 1112 extends to nearside guide line port one 111 from the distal guide line cap 1110 of elongated axostylus axostyle 1104 distal end, nearside guide line port one 111 than the proximal end of conduit axostylus axostyle 1104 closer to distal port 1110.Connector 1116 connects with the proximal end of elongated axostylus axostyle 1104.Connector 1116 is preferably luer connector element, and this permission connects with decompressor or other device with inflation utricule 1106 easily.First conduit 1102 is arranged in the central passage 1126 of capture duct 1124, and this central area has punched areas 1145.Central passage 1126 size is made adaptive with axostylus axostyle 1104,1132 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 1104 can slide in central passage 1126, or the lock ring 1125 of its available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1104, usually near utricule 1106 and/or support 1108, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.Suitably located once conduit and no longer needed, the punched areas 1145 along capture duct 1124 allows capture duct to peel off easily from two conduit axostylus axostyles 1104,1132.

Second conduit 1130 comprises elongated axostylus axostyle 1132, and being provided with near the distal end of elongated axostylus axostyle 1132 can radial dilatation utricule 1140.Support 1142 is arranged on utricule 1140.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1142 is shorter than the active length of utricule 1140, thus the nearly portion of utricule 1140 is not by the constraint of support 1142, and this of utricule 1140 is unfettered partially passes through side opening 1120 and advance slidably below the nearly portion 1122 of support 1108 or retract, this will hereinafter be described.Support 1142 pressure is held utricule 1140 and is ejected during preventing conveying.Utricule 1140 distad offset to make the profile of device minimum relative to utricule 1106 and support 1108 with support 1142 at least partially.In this embodiment, distal stent 1142 can be launched in the main split of vascular, and another support 1108 can launch in the side branch of vascular.Or distal stent 1142 can be launched in the side branch of vascular, and another support 1108 can launch in the main split of vascular.Second conduit 1130 is the rapid-exchange catheter (RX) with guidewire lumen 1134, guidewire lumen 1134 extends to nearside guide line port one 136 from the distal guide line cap 1138 of elongated axostylus axostyle 1132 distal end, nearside guide line port one 136 than the proximal end of conduit axostylus axostyle 1132 closer to distal port 1138.Nearside guide line port one 136 does not also hinder by capture duct 1124 and can in its distally.Preferably for the connector 1144 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1132, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1132 with inflation utricule 1140.A part for axostylus axostyle 1132 is arranged in the central passage 1126 of capture duct 1124, and this contributes to keeping two conduit axostylus axostyles 1104,1132 parallel and prevent from tangling during carrying and when axostylus axostyle 1132 is advanced slidably in central passage 1126.Compression fitting 1125 can be used for being locked in by elongated axostylus axostyle 1104,1132 in capture duct 1124 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, another part of axostylus axostyle 1132 is arranged on below the nearly portion 1122 of support 1108.Second conduit 1130 also can be advanced slidably or retract below the nearly portion 1122 of support 1108, thus axostylus axostyle 1132 is through the side opening 1120 in support 1108.Capture duct 1124 is peeled off from axostylus axostyle 1132 by breaking punched areas 1145.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1132, usually near utricule 1140 or support 1142, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 12 A illustrates conduit system 1200, and two being enclosed within guide line comprised with detachable capture duct is designed.Figure 12 B clearly show that the feature of conduit system 1200 in Figure 12 A.Stent delivery system 1200 comprises the first conduit 1202 and the second conduit 1230.First conduit 1202 comprises elongated axostylus axostyle 1204, and being provided with near the distal end of elongated axostylus axostyle 1204 can radial dilatation utricule 1206.There is nearly portion 1222, the support 1208 of distal part 1214 and side opening 1220 is arranged on utricule 1206.Distal part 1214 pressure is held utricule 1206 and is ejected during preventing conveying, and nearly portion 1222 partly presses and holds utricule 1206, thus the second conduit 1230 can be advanced in nearly portion 1222 slid underneath of support 1208.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1210 of elongated axostylus axostyle 1204 distal end to elongated axostylus axostyle 1204 extends to the guidewire lumen 1212 of the Y shape adapter 1214 with connector 1216.Connector 1216 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1212 is drawn via connector 1216.Second connector 1218 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1206 in elongated axostylus axostyle 1204.First conduit 1202 is arranged in the central passage 1226 of capture duct 1224, and this central passage has punched areas 1245.Central passage 1226 size is made adaptive with axostylus axostyle 1204,1232 and is allowed axostylus axostyle to move slidably.Axostylus axostyle 1204 can slide in central passage 1226, or the lock ring 1225 of its available such as Tuohy-Borst compression fitting and so on locks.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1204, usually near utricule 1206 and/or support 1208, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.Suitably located once conduit and no longer needed, the punched areas 1245 along capture duct 1224 allows capture duct to peel off easily from two conduit axostylus axostyles 1204,1232.

Second conduit 1230 comprises elongated axostylus axostyle 1232, and being provided with near the distal end of elongated axostylus axostyle 1232 can radial dilatation utricule 1240.Support 1242 is arranged on utricule 1240.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1242 is shorter than the active length of utricule 1240, thus the nearly portion of utricule 1240 is not by the constraint of support 1242, and this of utricule 1240 is unfettered partially passes through side opening 1220 and advance slidably below the nearly portion 1222 of support 1208 or retract, this will hereinafter be described.Support 1242 pressure is held utricule 1240 and is ejected during preventing conveying.Utricule 1240 distad offset to make the profile of device minimum relative to utricule 1206 and support 1208 with support 1242 at least partially.In this embodiment, distal stent 1242 can be launched in the main split of vascular, and another support 1208 can launch in the side branch of vascular.Or distal stent 1242 can be launched in the side branch of vascular, and another support 1208 can launch in the main split of vascular.Second conduit 1230 is the conduits being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1238 of elongated axostylus axostyle 1232 distal end to elongated axostylus axostyle 1232 extends to the guidewire lumen 1234 of the Y shape adapter 1246 with connector 1248.Connector 1248 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1234 is drawn via connector 1248.Second connector 1244 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1240 in elongated axostylus axostyle 1232.A part for axostylus axostyle 1232 is arranged in the central passage 1226 of capture duct 1224, and this contributes to keeping two conduit axostylus axostyles 1204,1232 parallel and prevent from tangling during carrying and when axostylus axostyle 1232 is advanced slidably in central passage 1226.Compression fitting 1225 can be used for being locked in by elongated axostylus axostyle 1204,1232 in capture duct 1224 to prevent axially-movable.Compression fitting can be Tuohy-Borst accessory.In addition, another part of axostylus axostyle 1232 is arranged on below the nearly portion 1222 of support 1208.Second conduit 1230 also can be advanced slidably or retract below the nearly portion 1222 of support 1208, thus axostylus axostyle 1232 is through the side opening 1220 in support 1208.Capture duct 1224 is peeled off from axostylus axostyle 1232 by breaking punched areas 1245.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1232, usually near utricule 1240 or support 1242, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 13 A, 14A, 15A and 16A illustrate that permission one conduit snaps in the slide fastener of another conduit.Slide fastener is form depression to receive cross section and the groove be linearly engraved in the outer surface of conduit substantially.Groove can be single groove on the definite part of conduit and can extend to the other end from one end.Or, a series of short groove of length 1 to 10 centimetre that conduit can to have in the length of conduit or only definite part to extend.The end-to-end slide fastener of complete length can have the profile the friction of reduction and vascular that reduce.Another conduit of groove receivability formed also prevents conduit from operator, conduit is advanced to the same hour offset of furcation.Once conduit still can be made relative to each other to move slidably forward and backward this position operation person.The total head utilizing female conduit of groove can have described in above-mentioned several embodiment holds support; But operator also can be allowed to select, and any business is commercially available has support or do not have standoff conduit and install business commercially available conduit via slide fastener.The female support being female conduit of free slide fastener can have pressure to be completely held in the utricule part of distally.After the commercially available conduit of loading business, the nearly portion pressure of female support must be held in place by operator before starting clinical course.This selection may be very important for operator, and operator can reduce the total stock of its conduit but have the more more options in process bifurcated lesions portion.

Figure 13 A illustrates conduit system 1300, comprises having being enclosed within the sub-conduit in the distally that guide line designs and having the female conduit of the nearside exchanging design and short slide fastener fast.Figure 13 B clearly show that the feature of conduit system 1300 in Figure 13 A.Stent delivery system 1300 comprises the first conduit 1302 and the second conduit 1330.First conduit 1302 comprises elongated axostylus axostyle 1304, and being provided with near the distal end of elongated axostylus axostyle 1304 can radial dilatation utricule 1306.There is nearly portion 1322, the support 1308 of distal part 1314 and side opening 1320 is arranged on utricule 1306.Distal part 1314 pressure is held utricule 1306 and is ejected during preventing conveying, and nearly portion 1322 partly presses and holds utricule 1306, thus the second conduit 1330 can be advanced in nearly portion 1322 slid underneath of support 1308.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1310 of elongated axostylus axostyle 1304 distal end to elongated axostylus axostyle 1304 extends to the guidewire lumen 1312 of the Y shape adapter 1314 with connector 1316.Connector 1316 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1312 is drawn via connector 1316.Second connector 1318 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1306 in elongated axostylus axostyle 1304.First conduit 1302 also comprises the slide fastener or card accessory 1324 that are connected to elongated axostylus axostyle 1304.Card pipe arrangement 1324 jointly can extrude with the first axostylus axostyle 1304 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1324 alternately connects with another axostylus axostyle 1332.Card accessory 1324 comprises the central passage 1326 that extends through wherein and size makes a part of receiving the second conduit 1330 slidably.Elongated slot 1345 extends along the total length of card accessory 1324, and size is made and axostylus axostyle 1336 can be blocked be fitted in central passage 1326.Figure 13 C illustrates the partial sectional view of Figure 13 B that C-C along the line intercepts, and the axostylus axostyle 1304 with card accessory 1324 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1304, usually near utricule 1306 and/or support 1308, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1330 comprises elongated axostylus axostyle 1332, and being provided with near the distal end of elongated axostylus axostyle 1332 can radial dilatation utricule 1340.Support 1342 is arranged on utricule 1340.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1342 is shorter than the active length of utricule 1340, thus the nearly portion of utricule 1340 is not by the constraint of support 1342, and this of utricule 1340 is unfettered partially passes through side opening 1320 and advance slidably below the nearly portion 1322 of support 1308 or retract, this will hereinafter be described.Support 1342 pressure is held utricule 1340 and is ejected during preventing conveying.Utricule 1340 distad offset to make the profile of device minimum relative to utricule 1306 and support 1308 with support 1342 at least partially.In this embodiment, distal stent 1342 can be launched in the main split of vascular, and another support 1308 can launch in the side branch of vascular.Or distal stent 1342 can be launched in the side branch of vascular, and another support 1308 can launch in the main split of vascular.Second conduit 1330 is the rapid-exchange catheter (RX) with guidewire lumen 1334, guidewire lumen 1334 extends to nearside guide line port one 336 from the distal guide line cap 1338 of elongated axostylus axostyle 1332 distal end, nearside guide line port one 336 than the proximal end of conduit axostylus axostyle 1332 closer to distal port 1338.Nearside guide line port one 336 does not also hinder by card accessory 1324 and preferably at its nearside.Preferably for the connector 1344 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1332, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1332 with inflation utricule 1340.A part for axostylus axostyle 1332 is fitted on the central passage 1326 of card accessory 1324 via groove 1345 card, and therefore axostylus axostyle 1332 can slide in passage 1326.This contribute to during carrying and axostylus axostyle 1332 is advanced slidably relative to axostylus axostyle 1304 or retract time keep two conduit axostylus axostyles 1304,1332 parallel and prevent from tangling.In addition, another part of axostylus axostyle 1332 is arranged on below the nearly portion 1322 of support 1308.Second conduit 1330 also can be advanced slidably or retract below the nearly portion 1322 of support 1308, thus axostylus axostyle 1332 is through the side opening 1320 in support 1308.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1332, usually near utricule 1340 or support 1342, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 14 A illustrates conduit system 1400, comprises and has the female conduit of the nearside exchanging structure fast and have the sub-conduit in distally being enclosed within structure and short slide fastener or card accessory on guide line.Figure 14 B clearly show that the feature of conduit system 1400 in Figure 14 A.Stent delivery system 1400 comprises the first conduit 1402 and the second conduit 1430.First conduit 1402 comprises elongated axostylus axostyle 1404, and being provided with near the distal end of elongated axostylus axostyle 1404 can radial dilatation utricule 1406, and utricule 1406 is provided with support 1408.Support 1408 can have the length identical with the active length of utricule 1408, or it can be shorter.In the preferred embodiment, support 1408 is shorter than the active length of utricule 1406, makes the nearly portion of utricule 1406 keep not limiting by support 1408.Can advance slidably via side opening 1420 and retract in the nearly portion of utricule 1406 below support 1442.Support 1408 pressure is held utricule 1406 and is ejected during preventing conveying.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1410 of elongated axostylus axostyle 1404 distal end to elongated axostylus axostyle 1404 extends to the guidewire lumen 1412 of the Y shape adapter 1414 with connector 1416.Connector 1416 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1412 is drawn via connector 1416.Second connector 1418 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1406 in elongated axostylus axostyle 1404.First conduit 1402 also comprises the slide fastener or card accessory 1424 that are connected to elongated axostylus axostyle 1404.Card pipe arrangement 1424 jointly can extrude with the first axostylus axostyle 1404 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1424 alternately connects with another axostylus axostyle 1432.Card accessory 1424 comprises the central passage 1426 that extends through wherein and size makes a part of receiving the second conduit 1430 slidably.Elongated slot 1445 extends along the total length of card accessory 1424, and size is made axostylus axostyle 1436 and can be blocked and be fitted in central passage 1426.Figure 14 C illustrates the partial sectional view of Figure 14 B that C-C along the line intercepts, and the axostylus axostyle 1404 with card accessory 1424 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1404, usually near utricule 1406 and/or support 1408, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1430 comprises elongated axostylus axostyle 1432, and being provided with near the distal end of elongated axostylus axostyle 1432 can radial dilatation utricule 1440.There is nearly portion 1422, the support 1442 of distal part 1414 and side opening 1420 is arranged on utricule 1440.Distal part 1414 pressure is held utricule 1440 and is ejected during preventing conveying, and nearly portion 1422 partly presses and holds utricule 1440, thus elongated axostylus axostyle 1404 can be advanced slidably or retract below the nearly portion 1422 of support 1442.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Utricule 1406 distad offset to make the profile of device minimum relative to utricule 1440 and support 1442 with support 1408 at least partially.In this embodiment, distal stent 1408 can be launched in the main split of vascular, and another support 1442 can launch in the side branch of vascular.Or distal stent 1408 can be launched in the side branch of vascular, and another support 1442 can launch in the main split of vascular.Second conduit 1430 is the rapid-exchange catheter (RX) with guidewire lumen 1434, guidewire lumen 1434 extends to nearside guide line port one 436 from the distal guide line cap 1438 of elongated axostylus axostyle 1432 distal end, nearside guide line port one 436 than the proximal end of conduit axostylus axostyle 1432 closer to distal port 1438.Nearside guide line port one 436 does not also hinder by card accessory 1424 and preferably at its nearside.Preferably for the connector 1444 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1432, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1432 with inflation utricule 1440.A part for axostylus axostyle 1432 is fitted in the central passage 1426 of card accessory 1424 via groove 1445 card, and therefore axostylus axostyle 1432 can slide in passage 1426.This contribute to during carrying and axostylus axostyle 1432 is advanced slidably relative to axostylus axostyle 1404 or retract time keep two conduit axostylus axostyles 1404,1432 parallel and prevent from tangling.In addition, a part for axostylus axostyle 1404 is arranged on below the nearly portion 1422 of support 1442.First conduit 1402 also can be advanced slidably or retract below the nearly portion 1422 of support 1442, thus axostylus axostyle 1404 is through the side opening 1420 in support 1442.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1432, usually near utricule 1440 or support 1442, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 15 A illustrates conduit system 1500, and the double quick speed comprised with short slide fastener or card accessory exchanges design.Figure 15 B clearly show that the feature of conduit system 1500 in Figure 15 A.Stent delivery system 1500 comprises the first conduit 1502 and the second conduit 1530.First conduit 1502 comprises elongated axostylus axostyle 1504, and being provided with near the distal end of elongated axostylus axostyle 1504 can radial dilatation utricule 1506.There is nearly portion 1522, the support 1508 of distal part 1514 and side opening 1520 is arranged on utricule 1506.Distal part 1514 pressure is held utricule 1506 and is ejected during preventing conveying, and nearly portion 1522 partly presses and holds utricule 1506, thus the second conduit 1530 can be advanced in nearly portion 1522 slid underneath of support 1508.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 1512, guidewire lumen 1512 extends to nearside guide line port one 511 from the distal guide line cap 1510 of elongated axostylus axostyle 1504 distal end, nearside guide line port one 511 than the proximal end of conduit axostylus axostyle 1504 closer to distal port 1510.Connector 1516 connects with the proximal end of elongated axostylus axostyle 1504.Connector 1516 is preferably luer connector element, and this permission connects with decompressor or other device with inflation utricule 1506 easily.First conduit 1502 also comprises the slide fastener or card accessory 1524 that are connected to elongated axostylus axostyle 1504.Card pipe arrangement 1524 jointly can extrude with the first axostylus axostyle 1504 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1524 alternately connects with another axostylus axostyle 1532.Card accessory 1524 comprises the central passage 1526 that extends through wherein and size makes a part of receiving the second conduit 1530 slidably.Elongated slot 1545 extends along the total length of card accessory 1524, and size is made axostylus axostyle 1536 and can be blocked and be fitted in central passage 1526.Figure 15 C illustrates the partial sectional view of Figure 15 B that C-C along the line intercepts, and the axostylus axostyle 1504 with card accessory 1524 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1504, usually near utricule 1506 and/or support 1508, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1530 comprises elongated axostylus axostyle 1532, and being provided with near the distal end of elongated axostylus axostyle 1532 can radial dilatation utricule 1540.Support 1542 is arranged on utricule 1540.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1542 is shorter than the active length of utricule 1540, thus the nearly portion of utricule 1540 is not by the constraint of support 1542, and this of utricule 1540 is unfettered partially passes through side opening 1520 and advance slidably below the nearly portion 1522 of support 1508 or retract, this will hereinafter be described.Support 1542 pressure is held utricule 1540 and is ejected during preventing conveying.Utricule 1540 distad offset to make the profile of device minimum relative to utricule 1506 and support 1508 with support 1542 at least partially.In this embodiment, distal stent 1542 can be launched in the main split of vascular, and another support 1508 can launch in the side branch of vascular.Or distal stent 1542 can be launched in the side branch of vascular, and another support 1508 can launch in the main split of vascular.Second conduit 1530 is the rapid-exchange catheter (RX) with guidewire lumen 1534, guidewire lumen 1534 extends to nearside guide line port one 536 from the distal guide line cap 1538 of elongated axostylus axostyle 1532 distal end, nearside guide line port one 536 than the proximal end of conduit axostylus axostyle 1532 closer to distal port 1538.Nearside guide line port one 536 does not also hinder by card accessory 1524 and can in its distally.Preferably for the connector 1544 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1532, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1532 with inflation utricule 1540.A part for axostylus axostyle 1532 is fitted in the central passage 1526 of card accessory 1524 via groove 1545 card, and therefore axostylus axostyle 1532 can slide in passage 1526.This contribute to during carrying and axostylus axostyle 1532 is advanced slidably relative to axostylus axostyle 1504 or retract time keep two conduit axostylus axostyles 1504,1532 parallel and prevent from tangling.In addition, another part of axostylus axostyle 1532 is arranged on below the nearly portion 1522 of support 1508.Second conduit 1530 also can be advanced slidably or retract below the nearly portion 1522 of support 1508, thus axostylus axostyle 1532 is through the side opening 1520 in support 1508.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1532, usually near utricule 1540 or support 1542, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 16 A illustrates conduit system 1600, comprises and designing with short slide fastener or being enclosed within guide line of card accessory.Figure 16 B clearly show that the feature of conduit system 1600 in Figure 16 A.Stent delivery system 1600 comprises the first conduit 1602 and the second conduit 1630.First conduit 1602 comprises elongated axostylus axostyle 1604, and being provided with near the distal end of elongated axostylus axostyle 1604 can radial dilatation utricule 1606.There is nearly portion 1622, the support 1608 of distal part 1614 and side opening 1620 is arranged on utricule 1606.Distal part 1614 pressure is held utricule 1606 and is ejected during preventing conveying, and nearly portion 1622 partly presses and holds utricule 1606, thus the second conduit 1630 can be advanced in nearly portion 1622 slid underneath of support 1608.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1610 of elongated axostylus axostyle 1604 distal end to elongated axostylus axostyle 1604 extends to the guidewire lumen 1612 of the Y shape adapter 1614 with connector 1616.Connector 1616 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1612 is drawn via connector 1616.Second connector 1618 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1606 in elongated axostylus axostyle 1604.First conduit 1602 also comprises the slide fastener or card accessory 1624 that are connected to elongated axostylus axostyle 1604.Card pipe arrangement 1624 jointly can extrude with the first axostylus axostyle 1604 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1624 alternately connects with another axostylus axostyle 1632.Card accessory 1624 comprises the central passage 1626 that extends through wherein and size makes a part of receiving the second conduit 1630 slidably.Elongated slot 1645 extends along the total length of card accessory 1624, and size is made axostylus axostyle 1636 and can be blocked and be fitted in central passage 1626.Figure 16 C illustrates the partial sectional view of Figure 16 B that C-C along the line intercepts, and the axostylus axostyle 1604 with card accessory 1624 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1604, usually near utricule 1606 and/or support 1608, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1630 comprises elongated axostylus axostyle 1632, and being provided with near the distal end of elongated axostylus axostyle 1632 can radial dilatation utricule 1640.Support 1642 is arranged on utricule 1640.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1642 is shorter than the active length of utricule 1640, thus the nearly portion of utricule 1640 is not by the constraint of support 1642, and this of utricule 1640 is unfettered partially passes through side opening 1620 and advance slidably below the nearly portion 1622 of support 1608 or retract, this will hereinafter be described.Support 1642 pressure is held utricule 1640 and is ejected during preventing conveying.Utricule 1640 distad offset to make the profile of device minimum relative to utricule 1606 and support 1608 with support 1642 at least partially.In this embodiment, distal stent 1642 can be launched in the main split of vascular, and another support 1608 can launch in the side branch of vascular.Or distal stent 1642 can be launched in the side branch of vascular, and another support 1608 can launch in the main split of vascular.Second conduit 1630 is the conduits being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1638 of elongated axostylus axostyle 1632 distal end to elongated axostylus axostyle 1632 extends to the guidewire lumen 1634 of the Y shape adapter 1646 with connector 1648.Connector 1648 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1634 is drawn via connector 1648.Second connector 1644 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1640 in elongated axostylus axostyle 1632.A part for axostylus axostyle 1632 is fitted in the central passage 1626 of card accessory 1624 via groove 1645 card, and therefore axostylus axostyle 1632 can slide in passage 1626.This contribute to during carrying and axostylus axostyle 1632 is advanced slidably relative to axostylus axostyle 1604 or retract time keep two conduit axostylus axostyles 1604,1632 parallel and prevent from tangling.In addition, another part of axostylus axostyle 1632 is arranged on below the nearly portion 1622 of support 1608.Second conduit 1630 also can be advanced slidably or retract below the nearly portion 1622 of support 1608, thus axostylus axostyle 1632 is through the side opening 1620 in support 1608.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1632, usually near utricule 1640 or support 1642, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 17 A illustrates conduit system 1700, comprises the sub-conduit in distally that has and exchange fast structure and has the female conduit of the nearside being enclosed within structure and end-to-end slide fastener or card accessory on guide line.This embodiment is similar to the embodiment shown in Figure 13 A-13B, and the main distinction is the position of one of the length and guide line port of card accessory.Figure 17 B clearly show that the feature of conduit system 1700 in Figure 17 A.Stent delivery system 1700 comprises the first conduit 1702 and the second conduit 1730.First conduit 1702 comprises elongated axostylus axostyle 1704, and being provided with near the distal end of elongated axostylus axostyle 1704 can radial dilatation utricule 1706.There is nearly portion 1722, the support 1708 of distal part 1714 and side opening 1720 is arranged on utricule 1706.Distal part 1714 pressure is held utricule 1706 and is ejected during preventing conveying, and nearly portion 1722 partly presses and holds utricule 1706, thus the second conduit 1730 can be advanced in nearly portion 1722 slid underneath of support 1708.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1710 of elongated axostylus axostyle 1704 distal end to elongated axostylus axostyle 1704 extends to the guidewire lumen 1712 of the Y shape adapter 1714 with connector 1716.Connector 1716 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1712 is drawn via connector 1716.Second connector 1718 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1706 in elongated axostylus axostyle 1704.First conduit 1702 also comprises the slide fastener or card accessory 1724 that are connected to elongated axostylus axostyle 1704.Card pipe arrangement 1724 jointly can extrude with the first axostylus axostyle 1704 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1724 alternately connects with another axostylus axostyle 1732.Card accessory 1724 comprises the central passage 1726 that extends through wherein and size makes a part of receiving the second conduit 1730 slidably.Elongated slot 1745 extends along the total length of card accessory 1724, and size is made axostylus axostyle 1736 and can be blocked and be fitted in central passage 1726.Card accessory 1724 can extend to the proximal end of utricule 1706 from the distal end of connector 1714,1744, or it can be shorter, only partly extends between connector 1714,1744 and utricule 1706.Figure 17 C illustrates the partial sectional view of Figure 17 B that C-C along the line intercepts, and the axostylus axostyle 1704 with card accessory 1724 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1704, usually near utricule 1706 and/or support 1708, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1730 comprises elongated axostylus axostyle 1732, and being provided with near the distal end of elongated axostylus axostyle 1732 can radial dilatation utricule 1740.Support 1742 is arranged on utricule 1740.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1742 is shorter than the active length of utricule 1740, thus the nearly portion of utricule 1740 is not by the constraint of support 1742, and this of utricule 1740 is unfettered partially passes through side opening 1720 and advance slidably below the nearly portion 1722 of support 1708 or retract, this will hereinafter be described.Support 1742 pressure is held utricule 1740 and is ejected during preventing conveying.Utricule 1740 distad offset to make the profile of device minimum relative to utricule 1706 and support 1708 with support 1742 at least partially.In this embodiment, distal stent 1742 can be launched in the main split of vascular, and another support 1708 can launch in the side branch of vascular.Or distal stent 1742 can be launched in the side branch of vascular, and another support 1708 can launch in the main split of vascular.Second conduit 1730 is the rapid-exchange catheter (RX) with guidewire lumen 1734, guidewire lumen 1734 extends to nearside guide line port one 736 from the distal guide line cap 1738 of elongated axostylus axostyle 1732 distal end, nearside guide line port one 736 than the proximal end of conduit axostylus axostyle 1732 closer to distal port 1738.Nearside guide line port one 736 does not also hinder by card accessory 1724 and preferably in its distally.Preferably for the connector 1744 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1732, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1732 with inflation utricule 1740.A part for axostylus axostyle 1732 is fitted in the central passage 1726 of card accessory 1724 via groove 1745 card, and therefore axostylus axostyle 1732 can slide in passage 1726.This contribute to during carrying and axostylus axostyle 1732 is advanced slidably relative to axostylus axostyle 1704 or retract time keep two conduit axostylus axostyles 1704,1732 parallel and prevent from tangling.In addition, another part of axostylus axostyle 1732 is arranged on below the nearly portion 1722 of support 1708.Second conduit 1730 also can be advanced slidably or retract below the nearly portion 1722 of support 1708, thus axostylus axostyle 1732 is through the side opening 1720 in support 1708.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1732, usually near utricule 1740 or support 1742, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 18 A illustrates conduit system 1800, comprises the sub-conduit in distally having the female conduit of the nearside exchanging structure fast and have end-to-end slide fastener or card accessory.Figure 18 category-A is similar to the embodiment shown in Figure 14 A-14B, and the main distinction is the position of one of the length and guide line port of card accessory.Figure 18 B clearly show that the feature of conduit system 1800 in Figure 18 A.Stent delivery system 1800 comprises the first conduit 1802 and the second conduit 1830.First conduit 1802 comprises elongated axostylus axostyle 1804, and being provided with near the distal end of elongated axostylus axostyle 1804 can radial dilatation utricule 1806, and utricule 1806 is provided with support 1808.Support 1808 can have the length identical with the active length of utricule 1808, or it can be shorter.In the preferred embodiment, support 1808 is shorter than the active length of utricule 1806, makes the nearly portion of utricule 1806 keep not limiting by support 1808.Can advance slidably via side opening 1820 and retract in the nearly portion of utricule 1806 below support 1842.Support 1808 pressure is held utricule 1806 and is ejected during preventing conveying.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 1810 of elongated axostylus axostyle 1804 distal end to elongated axostylus axostyle 1804 extends to the guidewire lumen 1812 of the Y shape adapter 1814 with connector 1816.Connector 1816 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 1812 is drawn via connector 1816.Second connector 1818 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 1806 in elongated axostylus axostyle 1804.First conduit 1802 also comprises the slide fastener or card accessory 1824 that are connected to elongated axostylus axostyle 1804.Card pipe arrangement 1824 jointly can extrude with the first axostylus axostyle 1804 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1824 alternately connects with another axostylus axostyle 1832.Card accessory 1824 comprises the central passage 1826 that extends through wherein and size makes a part of receiving the second conduit 1830 slidably.Elongated slot 1845 extends along the total length of card accessory 1824, and size is made axostylus axostyle 1836 and can be blocked and be fitted in central passage 1826.Figure 18 C illustrates the partial sectional view of Figure 18 B that C-C along the line intercepts, and the axostylus axostyle 1804 with card accessory 1824 is shown.Card accessory 1824 can extend to the proximal end of utricule 1840 from the distal end of connector 1814,1844, or it can be shorter, only partly extends between connector 1814,1844 and utricule 1806.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1804, usually near utricule 1806 and/or support 1808, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1830 comprises elongated axostylus axostyle 1832, and being provided with near the distal end of elongated axostylus axostyle 1832 can radial dilatation utricule 1840.There is nearly portion 1822, the support 1842 of distal part 1814 and side opening 1820 is arranged on utricule 1840.Distal part 1814 pressure is held utricule 1840 and is ejected during preventing conveying, and nearly portion 1822 partly presses and holds utricule 1840, thus elongated axostylus axostyle 1804 can be advanced slidably or retract below the nearly portion 1822 of support 1842.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Utricule 1806 distad offset to make the profile of device minimum relative to utricule 1840 and support 1842 with support 1808 at least partially.In this embodiment, distal stent 1808 can be launched in the main split of vascular, and another support 1842 can launch in the side branch of vascular.Or distal stent 1808 can be launched in the side branch of vascular, and another support 1842 can launch in the main split of vascular.Second conduit 1830 is the rapid-exchange catheter (RX) with guidewire lumen 1834, guidewire lumen 1834 extends to nearside guide line port one 836 from the distal guide line cap 1838 of elongated axostylus axostyle 1832 distal end, nearside guide line port one 836 than the proximal end of conduit axostylus axostyle 1832 closer to distal port 1838.Nearside guide line port one 836 does not also hinder by card accessory 1824 and preferably in its distally.Preferably for the connector 1844 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1832, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1832 with inflation utricule 1840.A part for axostylus axostyle 1832 is fitted in the central passage 1826 of card accessory 1824 via groove 1845 card, and therefore axostylus axostyle 1832 can slide in passage 1826.This contribute to during carrying and axostylus axostyle 1832 is advanced slidably relative to axostylus axostyle 1804 or retract time keep two conduit axostylus axostyles 1804,1832 parallel and prevent from tangling.In addition, a part for axostylus axostyle 1804 is arranged on below the nearly portion 1822 of support 1842.First conduit 1802 also can be advanced slidably or retract below the nearly portion 1822 of support 1842, thus axostylus axostyle 1804 is through the side opening 1820 in support 1842.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1832, usually near utricule 1840 or support 1842, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 19 A illustrates conduit system 1900, and the double quick speed comprised with end-to-end slide fastener or card accessory exchanges design.Figure 19 category-A is similar to the embodiment of Figure 15 A-15B, and the main distinction is the length of card accessory.Figure 19 B clearly show that the feature of conduit system 1900 in Figure 19 A.Stent delivery system 1900 comprises the first conduit 1902 and the second conduit 1930.First conduit 1902 comprises elongated axostylus axostyle 1904, and being provided with near the distal end of elongated axostylus axostyle 1904 can radial dilatation utricule 1906.There is nearly portion 1922, the support 1908 of distal part 1914 and side opening 1920 is arranged on utricule 1906.Distal part 1914 pressure is held utricule 1906 and is ejected during preventing conveying, and nearly portion 1922 partly presses and holds utricule 1906, thus the second conduit 1930 can be advanced in nearly portion 1922 slid underneath of support 1908.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 1912, guidewire lumen 1912 extends to nearside guide line port one 911 from the distal guide line cap 1910 of elongated axostylus axostyle 1904 distal end, nearside guide line port one 911 than the proximal end of conduit axostylus axostyle 1904 closer to distal port 1910.Connector 1916 connects with the proximal end of elongated axostylus axostyle 1904.Connector 1916 is preferably luer connector element, and this permission connects with decompressor or other device with inflation utricule 1906 easily.First conduit 1902 also comprises the slide fastener or card accessory 1924 that are connected to elongated axostylus axostyle 1904.Card pipe arrangement 1924 jointly can extrude with the first axostylus axostyle 1904 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 1924 alternately connects with another axostylus axostyle 1932.Card accessory 1924 comprises the central passage 1926 that extends through wherein and size makes a part of receiving the second conduit 1930 slidably.Elongated slot 1945 extends along the total length of card accessory 1924, and size is made axostylus axostyle 1932 and can be blocked and be fitted in central passage 1926.Figure 19 C illustrates the partial sectional view of Figure 19 B that C-C along the line intercepts, and the axostylus axostyle 1904 with card accessory 1924 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 1904, usually near utricule 1906 and/or support 1908, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 1930 comprises elongated axostylus axostyle 1932, and being provided with near the distal end of elongated axostylus axostyle 1932 can radial dilatation utricule 1940.Support 1942 is arranged on utricule 1940.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 1942 is shorter than the active length of utricule 1940, thus the nearly portion of utricule 1940 is not by the constraint of support 1942, and this of utricule 1940 is unfettered partially passes through side opening 1920 and advance slidably below the nearly portion 1922 of support 1908 or retract, this will hereinafter be described.Support 1942 pressure is held utricule 1940 and is ejected during preventing conveying.Utricule 1940 distad offset to make the profile of device minimum relative to utricule 1906 and support 1908 with support 1942 at least partially.In this embodiment, distal stent 1942 can be launched in the main split of vascular, and another support 1908 can launch in the side branch of vascular.Or distal stent 1942 can be launched in the side branch of vascular, and another support 1908 can launch in the main split of vascular.Second conduit 1930 is the rapid-exchange catheter (RX) with guidewire lumen 1934, guidewire lumen 1934 extends to nearside guide line port one 936 from the distal guide line cap 1938 of elongated axostylus axostyle 1932 distal end, nearside guide line port one 936 than the proximal end of conduit axostylus axostyle 1932 closer to distal port 1938.Nearside guide line port one 936 does not also hinder by card accessory 1924 and can in its distally.Preferably for the connector 1944 of luer connector element is connected to the proximal end of elongated axostylus axostyle 1932, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 1932 with inflation utricule 1940.A part for axostylus axostyle 1932 is fitted in the central passage 1924 of card accessory 1926 via groove 1945 card, and therefore axostylus axostyle 1932 can slide in passage 1926.This contribute to during carrying and axostylus axostyle 1932 is advanced slidably relative to axostylus axostyle 1904 or retract time keep two conduit axostylus axostyles 1904,1932 parallel and prevent from tangling.In addition, another part of axostylus axostyle 1932 is arranged on below the nearly portion 1922 of support 1908.Second conduit 1930 also can be advanced slidably or retract below the nearly portion 1922 of support 1908, thus axostylus axostyle 1932 is through the side opening 1920 in support 1908.Radiopaque labelling can be placed on diverse location on axostylus axostyle 1932, usually near utricule 1940 or support 1942, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 20 A illustrates conduit system 2000, comprises and designing with end-to-end slide fastener or being enclosed within guide line of card accessory.Figure 20 category-A is similar to the embodiment of Figure 16 A-16B, and the main distinction is the length of card accessory.Figure 20 B clearly show that the feature of conduit system 2000 in Figure 20 A.Stent delivery system 2000 comprises the first conduit 2002 and the second conduit 2030.First conduit 2002 comprises elongated axostylus axostyle 2004, and being provided with near the distal end of elongated axostylus axostyle 2004 can radial dilatation utricule 2006.There is nearly portion 2022, the support 2008 of distal part 2014 and side opening 2020 is arranged on utricule 2006.Distal part 2014 pressure is held utricule 2006 and is ejected during preventing conveying, and nearly portion 2022 partly presses and holds utricule 2006, thus the second conduit 2030 can be advanced in nearly portion 2022 slid underneath of support 2008.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 2010 of elongated axostylus axostyle 2004 distal end to elongated axostylus axostyle 2004 extends to the guidewire lumen 2012 of the Y shape adapter 2014 with connector 2016.Connector 2016 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 2012 is drawn via connector 2016.Second connector 2018 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 2006 in elongated axostylus axostyle 2004.First conduit 2002 also comprises the slide fastener or card accessory 2024 that are connected to elongated axostylus axostyle 2004.Card pipe arrangement 2024 jointly can extrude with the first axostylus axostyle 2004 and form, or it can bond or use technology well known by persons skilled in the art to be attached to the first axostylus axostyle.Card accessory 2024 alternately connects with another axostylus axostyle 2032.Card accessory 2024 comprises the central passage 2026 that extends through wherein and size makes a part of receiving the second conduit 2030 slidably.Elongated slot 2045 extends along the total length of card accessory 2024, and size is made axostylus axostyle 2036 and can be blocked and be fitted in central passage 2026.Figure 20 C illustrates the partial sectional view of Figure 20 B that C-C along the line intercepts, and the axostylus axostyle 2004 with card accessory 2024 is shown.Radiopaque labelling can be placed on diverse location along axostylus axostyle 2004, usually near utricule 2006 and/or support 2008, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 2030 comprises elongated axostylus axostyle 2032, and being provided with near the distal end of elongated axostylus axostyle 2032 can radial dilatation utricule 2040.Support 2042 is arranged on utricule 2040.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 2042 is shorter than the active length of utricule 2040, thus the nearly portion of utricule 2040 is not by the constraint of support 2042, and this of utricule 2040 is unfettered partially passes through side opening 2020 and advance slidably below the nearly portion 2022 of support 2008 or retract, this will hereinafter be described.Support 2042 pressure is held utricule 2040 and is ejected during preventing conveying.Utricule 2040 distad offset to make the profile of device minimum relative to utricule 2006 and support 2008 with support 2042 at least partially.In this embodiment, distal stent 2042 can be launched in the main split of vascular, and another support 2008 can launch in the side branch of vascular.Or distal stent 2042 can be launched in the side branch of vascular, and another support 2008 can launch in the main split of vascular.Second conduit 2030 is the conduits being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 2038 of elongated axostylus axostyle 2032 distal end to elongated axostylus axostyle 2032 extends to the guidewire lumen 2034 of the Y shape adapter 2046 with connector 2048.Connector 2048 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 2034 is drawn via connector 2048.Second connector 2044 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 2040 in elongated axostylus axostyle 2032.A part for axostylus axostyle 2032 is fitted in the central passage 2026 of card accessory 2024 via groove 2045 card, and therefore axostylus axostyle 2032 can slide in passage 2026.This contribute to during carrying and axostylus axostyle 2032 is advanced slidably relative to axostylus axostyle 2004 or retract time keep two conduit axostylus axostyles 2004,2032 parallel and prevent from tangling.In addition, another part of axostylus axostyle 2032 is arranged on below the nearly portion 2022 of support 2008.Second conduit 2030 also can be advanced slidably or retract below the nearly portion 2022 of support 2008, thus axostylus axostyle 2032 is through the side opening 2020 in support 2008.Radiopaque labelling can be placed on diverse location on axostylus axostyle 2032, usually near utricule 2040 or support 2042, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 21 A, 22A, 23A and 24A illustrate the conduit that can be used for alternate embodiment, and provide female conduit with female support in alternative embodiments to operator, female support pressure is held on the distal part of female catheter balloons.The nearly portion of female support does not press to hold or partly press and holds.Any business can be buied conduit or utricule by female support proximal end and to be arranged on guide line and to leave from the side opening of female support by operator.Conduit can be aimed at the anatomical structure adapting to patient and press the nearly portion of holding female support by operator.Operator can press tightly and hold support, thus conduit does not relative to each other move.Conduit can prevent at furcation place by operator, and if necessary retracts business and can buy conduit to regulate aligning where necessary.Then operator distad can touch system to guarantee complete juxtaposition.

Figure 21 A illustrates conduit system 2100, comprises the sub-conduit in distally with exchange structure fast and is enclosed within the female conduit of the nearside that guide line constructs with having.Figure 21 B clearly show that the feature of conduit system 2100 in Figure 21 A.Stent delivery system 2100 comprises the first conduit 2102 and the second conduit 2130.First conduit 2102 comprises elongated axostylus axostyle 2104, and being provided with near the distal end of elongated axostylus axostyle 2104 can radial dilatation utricule 2106.There is nearly portion 2122, the support 2108 of distal part 2114 and side opening 2120 is arranged on utricule 2106.Distal part 2114 pressure is held utricule 2106 and is ejected during preventing conveying, and nearly portion 2122 partly presses and holds utricule 2106, thus the second conduit 2130 can be advanced in nearly portion 2122 slid underneath of support 2108.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 2110 of elongated axostylus axostyle 2104 distal end to elongated axostylus axostyle 2104 extends to the guidewire lumen 2112 of the Y shape adapter 2114 with connector 2116.Connector 2116 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 2112 is drawn via connector 2116.Second connector 2118 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 2106 in elongated axostylus axostyle 2104.Radiopaque labelling can be placed on diverse location along axostylus axostyle 2104, usually near utricule 2106 and/or support 2108, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 2130 comprises elongated axostylus axostyle 2132, and being provided with near the distal end of elongated axostylus axostyle 2132 can radial dilatation utricule 2140.Support 2142 is arranged on utricule 2140.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 2142 is shorter than the active length of utricule 2140, thus the nearly portion of utricule 2140 is not by the constraint of support 2142, and this of utricule 2140 is unfettered partially passes through side opening 2120 and advance slidably below the nearly portion 2122 of support 2108 or retract, this will hereinafter be described.Support 2142 pressure is held utricule 2140 and is ejected during preventing conveying.Utricule 2140 distad offset to make the profile of device minimum relative to utricule 2106 and support 2108 with support 2142 at least partially.In this embodiment, distal stent 2142 can be launched in the main split of vascular, and another support 2108 can launch in the side branch of vascular.Or distal stent 2142 can be launched in the side branch of vascular, and another support 2108 can launch in the main split of vascular.Second conduit 2130 is the rapid-exchange catheter (RX) with guidewire lumen 2134, guidewire lumen 2134 extends to nearside guide line port 2136 from the distal guide line cap 2138 of elongated axostylus axostyle 2132 distal end, nearside guide line port 2136 than the proximal end of conduit axostylus axostyle 2132 closer to distal port 2138.Preferably for the connector 2144 of luer connector element is connected to the proximal end of elongated axostylus axostyle 2132, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 2132 with inflation utricule 2140.Contribute to keeping conduit 2104,2132 parallel and prevent from tangling below the portions of proximal 2122 part for axostylus axostyle 2132 being arranged on support 2108 during carrying and when axostylus axostyle 2132 advances slidably relative to axostylus axostyle 2104 or retracts.In addition, another part of axostylus axostyle 2132 is arranged on below the nearly portion 2122 of support 2108.Second conduit 2130 also can be advanced slidably or retract below the nearly portion 2122 of support 2108, thus axostylus axostyle 2132 is through the side opening 2120 in support 2108.Radiopaque labelling can be placed on diverse location on axostylus axostyle 2132, usually near utricule 2140 or support 2142, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 22 A illustrates conduit system 2200, comprises having to be enclosed within the female conduit of the nearside that guide line designs and to have being enclosed within the sub-conduit in the distally that guide line constructs.Figure 22 B clearly show that the feature of conduit system 2200 in Figure 22 A.Stent delivery system 2200 comprises the first conduit 2202 and the second conduit 2230.First conduit 2202 comprises elongated axostylus axostyle 2204, and being provided with near the distal end of elongated axostylus axostyle 2206 can radial dilatation utricule 2204, and utricule 2208 is provided with support 2206.Support 2208 can have the length identical with the active length of utricule 2208, or it can be shorter.In the preferred embodiment, support 2208 is shorter than the active length of utricule 2206, makes the nearly portion of utricule 2206 keep not limiting by support 2208.Can advance slidably via side opening 2220 and retract in the nearly portion of utricule 2206 below support 2242.Support 2208 pressure is held utricule 2206 and is ejected during preventing conveying.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 2210 of elongated axostylus axostyle 2204 distal end to elongated axostylus axostyle 2204 extends to the guidewire lumen 2212 of the Y shape adapter 2214 with connector 2216.Connector 2216 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 2212 is drawn via connector 2216.Second connector 2218 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 2206 in elongated axostylus axostyle 2204.Radiopaque labelling can be placed on diverse location along axostylus axostyle 2204, usually near utricule 2206 and/or support 2208, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 2230 comprises elongated axostylus axostyle 2232, and being provided with near the distal end of elongated axostylus axostyle 2232 can radial dilatation utricule 2240.There is nearly portion 2222, the support 2242 of distal part 2214 and side opening 2220 is arranged on utricule 2240.Distal part 2214 pressure is held utricule 2240 and is ejected during preventing conveying, and nearly portion 2222 partly presses and holds utricule 2240, thus elongated axostylus axostyle 2204 can be advanced slidably or retract below the nearly portion 2222 of support 2242.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Utricule 2206 distad offset to make the profile of device minimum relative to utricule 2240 and support 2242 with support 2208 at least partially.In this embodiment, distal stent 2208 can be launched in the main split of vascular, and another support 2242 can launch in the side branch of vascular.Or distal stent 2208 can be launched in the side branch of vascular, and another support 2242 can launch in the main split of vascular.Second conduit 2230 is the rapid-exchange catheter (RX) with guidewire lumen 2234, guidewire lumen 2234 extends to nearside guide line port 2236 from the distal guide line cap 2238 of elongated axostylus axostyle 2232 distal end, nearside guide line port 2236 than the proximal end of conduit axostylus axostyle 2232 closer to distal port 2238.Preferably for the connector 2244 of luer connector element is connected to the proximal end of elongated axostylus axostyle 2232, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 2232 with inflation utricule 2240.Contribute to during carrying below the nearly portion 2222 part for axostylus axostyle 2204 being arranged on support 2208 and axostylus axostyle 2204 is advanced slidably relative to axostylus axostyle 2232 or retract time keep conduit axostylus axostyle 2202,2232 parallel and prevent from tangling.First conduit 2202 also can be advanced slidably or retract below the nearly portion 2222 of support 2242, thus axostylus axostyle 2204 is through the side opening 2220 in support 2242.Radiopaque labelling can be placed on diverse location on axostylus axostyle 2232, usually near utricule 2240 or support 2242, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 23 A illustrates to have the conduit system 2300 that double quick speed exchanges design.Figure 23 B clearly show that the feature of conduit system 2300 in Figure 23 A.Stent delivery system 2300 comprises the first conduit 2302 and the second conduit 2330.First conduit 2302 comprises elongated axostylus axostyle 2304, and being provided with near the distal end of elongated axostylus axostyle 2304 can radial dilatation utricule 2306.There is nearly portion 2322, the support 2308 of distal part 2314 and side opening 2320 is arranged on utricule 2306.Distal part 2314 pressure is held utricule 2306 and is ejected during preventing conveying, and nearly portion 2322 partly presses and holds utricule 2306, thus the second conduit 2330 can be advanced in nearly portion 2322 slid underneath of support 2308.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 2312, guidewire lumen 2312 extends to nearside guide line port 2311 from the distal guide line cap 2310 of elongated axostylus axostyle 2304 distal end, nearside guide line port 2311 than the proximal end of conduit axostylus axostyle 2304 closer to distal port 2310.Connector 2316 connects with the proximal end of elongated axostylus axostyle 2304.Connector 2116 is preferably luer connector element, and this permission connects with decompressor or other device with inflation utricule 2306 easily.Radiopaque labelling can be placed on diverse location along axostylus axostyle 2304, usually near utricule 2306 and/or support 2308, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 2330 comprises elongated axostylus axostyle 2332, and being provided with near the distal end of elongated axostylus axostyle 2332 can radial dilatation utricule 2340.Support 2342 is arranged on utricule 2340.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 2342 is shorter than the active length of utricule 2340, thus the nearly portion of utricule 2340 is not by the constraint of support 2342, and this of utricule 2340 is unfettered partially passes through side opening 2320 and advance slidably below the nearly portion 2322 of support 2308 or retract, this will hereinafter be described.Support 2342 pressure is held utricule 2340 and is ejected during preventing conveying.Utricule 2340 distad offset to make the profile of device minimum relative to utricule 2306 and support 2308 with support 2342 at least partially.In this embodiment, distal stent 2342 can be launched in the main split of vascular, and another support 2308 can launch in the side branch of vascular.Or distal stent 2342 can be launched in the side branch of vascular, and another support 2308 can launch in the main split of vascular.Second conduit 2330 is the rapid-exchange catheter (RX) with guidewire lumen 2334, guidewire lumen 2334 extends to nearside guide line port 2336 from the distal guide line cap 2338 of elongated axostylus axostyle 2332 distal end, nearside guide line port 2336 than the proximal end of conduit axostylus axostyle 2332 closer to distal port 2338.Preferably for the connector 2344 of luer connector element is connected to the proximal end of elongated axostylus axostyle 2332, and decompressor or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 2332 with inflation utricule 2340.Contribute to during carrying below the nearly portion 2322 part for axostylus axostyle 2332 being arranged on support 2308 and axostylus axostyle 2332 is advanced slidably relative to axostylus axostyle 2304 or retract time keep conduit axostylus axostyle 2302,2332 parallel and prevent from tangling.Second conduit 2330 also can be advanced slidably or retract below the nearly portion 2322 of support 2308, thus axostylus axostyle 2332 is through the side opening 2320 in support 2308.Radiopaque labelling can be placed on diverse location on axostylus axostyle 2332, usually near utricule 2340 or support 2342, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Figure 24 A illustrates to have and two is enclosed within the conduit system 2400 that guide line designs.Figure 24 B clearly show that the feature of conduit system 2400 in Figure 24 A.Stent delivery system 2400 comprises the first conduit 2402 and the second conduit 2430.First conduit 2402 comprises elongated axostylus axostyle 2404, and being provided with near the distal end of elongated axostylus axostyle 2404 can radial dilatation utricule 2406.There is nearly portion 2422, the support 2408 of distal part 2414 and side opening 2420 is arranged on utricule 2406.Distal part 2414 pressure is held utricule 2406 and is ejected during preventing conveying, and nearly portion 2422 partly presses and holds utricule 2406, thus the second conduit 2430 can be advanced in nearly portion 2422 slid underneath of support 2408.First conduit is the conduit being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 2410 of elongated axostylus axostyle 2404 distal end to elongated axostylus axostyle 2404 extends to the guidewire lumen 2412 of the Y shape adapter 2414 with connector 2416.Connector 2416 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 2412 is drawn via connector 2416.Second connector 2418 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 2406 in elongated axostylus axostyle 2404.Radiopaque labelling can be placed on diverse location along axostylus axostyle 2404, usually near utricule 2406 and/or support 2408, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

Second conduit 2430 comprises elongated axostylus axostyle 2432, and being provided with near the distal end of elongated axostylus axostyle 2432 can radial dilatation utricule 2440.Support 2442 is arranged on utricule 2440.Support can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.In the preferred embodiment, support 2442 is shorter than the active length of utricule 2440, thus the nearly portion of utricule 2440 is not by the constraint of support 2442, and this of utricule 2440 is unfettered partially passes through side opening 2420 and advance slidably below the nearly portion 2422 of support 2408 or retract, this will hereinafter be described.Support 2442 pressure is held utricule 2440 and is ejected during preventing conveying.Utricule 2440 distad offset to make the profile of device minimum relative to utricule 2406 and support 2408 with support 2442 at least partially.In this embodiment, distal stent 2442 can be launched in the main split of vascular, and another support 2408 can launch in the side branch of vascular.Or distal stent 2442 can be launched in the side branch of vascular, and another support 2408 can launch in the main split of vascular.Second conduit 2430 is the conduits being enclosed within (OTW) on guide line, and the proximal end had from the distal guide line cap 2438 of elongated axostylus axostyle 2432 distal end to elongated axostylus axostyle 2432 extends to the guidewire lumen 2434 of the Y shape adapter 2446 with connector 2448.Connector 2448 is preferably luer connector element, and this allows convenient connection syringe or other is for carrying out the device of inner chamber flushing or inject contrast.When not connecting, guidewire lumen 2434 is drawn via connector 2448.Second connector 2444 is also preferably luer connector element, allows decompressor or other device to be attached to conduit with via the inflation lumen (not shown) inflation utricule 2440 in elongated axostylus axostyle 2432.Contribute to during carrying below the nearly portion 2422 part for axostylus axostyle 2432 being arranged on support 2408 and axostylus axostyle 2432 is advanced slidably relative to axostylus axostyle 2404 or retract time keep conduit axostylus axostyle 2402,2430 parallel and prevent from tangling.Second conduit 2430 also can be advanced slidably or retract below the nearly portion 2422 of support 2408, thus axostylus axostyle 2432 is through the side opening 2420 in support 2408.Radiopaque labelling can be placed on diverse location on axostylus axostyle 2432, usually near utricule 2440 or support 2442, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to the aligning that support launches period two conduit, as his place of this description is discussed.

In certain embodiments, only single support can be disposed at furcation place." mixing " method that the oral area of bifurcated stent opens is opened by the main split of vascular and a part of going back offside branch is opened, and keeps the patency along main split simultaneously.Figure 40-43 illustrates the exemplary embodiment that can be used for the system of carrying out this treatment.In addition, include but not limited to hollow switching port, capture duct, locking mechanism, the capture duct of perforation, polymer sleeve pipe and card accessory any one of above-mentioned feature optionally can be contained in the embodiment of Figure 40-43, but and not specified (NS).Equally, any commercial commercially available support can unchangeably or slightly modified ground be used for these systems.Commercial commercially available inflation catheter also can be bonded to each other and mate.

In Figure 40-43, visible embodiment can use as described hereinly, or they also can be used for treating furcation according to other method, such as previous with see mode include herein U.S. Patent application in disclose such.Figure 40 illustrates stent delivery system 4500.Stent delivery system 4500 comprises the first conduit 4502 and the second conduit 4530.First conduit 4502 comprises elongated axostylus axostyle 4504, and be provided with near the distal end of elongated axostylus axostyle 4504 can radial dilatation utricule 4506.There is nearly portion 4522, the support 4508 of distal part 4514 and side opening 4520 is arranged on utricule 4506.Distal part 4514 pressure holds utricule 4506, and to prevent from ejecting in course of conveying, and nearly portion 4522 partly press and holds utricule 4506, thus the second conduit 4530 can in the nearly portion 4522 slid underneath advance of support 4508.First conduit is the conduit being enclosed within (OTW) on guide line, this conduit has guidewire lumen 4512, and this guidewire lumen extends to the Y shape adapter 4514 with connector 4516 from the distal guide line cap 4510 of elongated axostylus axostyle 4504 distal end to the proximal end of elongated axostylus axostyle 4504.Connector 4516 is preferably Rule (Luer) connector, and this allows convenient connection syringe or other device for carrying out inner chamber flushing or inject contrast.When not connecting, guidewire lumen 4512 is drawn via connector 4516.Also be preferably that the second connector 4518 of luer connector element allows pressurizing device or other device to be attached to conduit, with via the inflation lumen (not shown) inflation utricule 4506 in elongated axostylus axostyle 4504.Radiopaque labelling can be placed on diverse location along axostylus axostyle 4504, usually near utricule 4506 and/or support 4508, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at this two conduits, as discussed in his place of this description during support launches.

Second conduit 4530 comprises elongated axostylus axostyle 4532, and being provided with near the distal end of elongated axostylus axostyle 4532 can radial dilatation utricule 4540.The portions of proximal of utricule 4540 can be advanced slidably via side opening 4520 or retracts, as discussed below below the portions of proximal 4522 of support 4508.Distad offseting relative to utricule 4506 and support 4508 at least partially of utricule 4540, to make the profile of device minimum.In this embodiment, support 4508 preferably can launch in the main split of vascular, but, it will be understood by those skilled in the art that support 4508 also can launch in the side branch of vascular.Second conduit 4530 is the rapid-exchange catheter (RX) with guidewire lumen 4534, this guidewire lumen extends to nearside guide line port 4536 from the distal guide line cap 4538 of elongated axostylus axostyle 4532 distal end, this nearside guide line port than the proximal end of conduit axostylus axostyle 4532 closer to distal port 4538.Preferably for the connector 4544 of luer connector element is connected to the proximal end of elongated axostylus axostyle 4532, and pressurizing device or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 4532, with inflation utricule 4540.Contribute to keeping conduit 4504,4532 parallel and prevent from tangling below the nearly portion 4508 part for axostylus axostyle 4532 being arranged on support 4522 during carrying and when axostylus axostyle 4532 advances slidably relative to axostylus axostyle 4504 or retracts.Equally, this guarantees that a part for utricule 4540 is also arranged on below the portions of proximal 4522 of support 4508, and thus, when utricule 4540 is by inflation, the portions of proximal 4522 of support 4508 will be expanded, and maintenance is not expanded by distal part 4514.Second conduit 4530 also can advance slidably or retract below the nearly portion 4522 of support 4508, thus axostylus axostyle 4532 is through the side opening 4520 in support 4508.Radiopaque labelling can be placed on diverse location on axostylus axostyle 4532, usually near utricule 4540 or support 4542, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at this two conduits, as discussed in his place of this description during support launches.

Figure 41 illustrates another embodiment of stent delivery system 4600.Stent delivery system 4600 comprises the first conduit 4602 and the second conduit 4630.First conduit 4602 comprises elongated axostylus axostyle 4604, and be provided with near the distal end of elongated axostylus axostyle 4604 can radial dilatation utricule 4606.The nearly portion of utricule 4606 can advance slidably via side opening 4620 and retract below support 4642.Therefore, the inflation of utricule 4606 also will make the portions of proximal 4622 of support 4642 expand, and the distal part 4614 of support 4642 keeps not expanding.First conduit is the conduit being enclosed within (OTW) on guide line, this conduit has guidewire lumen 4612, and this guidewire lumen extends to the Y shape adapter 4614 with connector 4616 from the distal guide line cap 4604 of elongated axostylus axostyle 4610 distal end to the proximal end of elongated axostylus axostyle 4604.Connector 4616 is preferably Rule (Luer) connector, and this allows convenient connection syringe or other device for carrying out inner chamber flushing or inject contrast.When not connecting, guidewire lumen 4612 is drawn via connector 4616.Also be preferably that the second connector 4618 of luer connector element allows pressurizing device or other device to be attached to conduit, with via the inflation lumen (not shown) inflation utricule 4606 in elongated axostylus axostyle 4604.Radiopaque labelling can be placed on along the diverse location of axostylus axostyle 4604, usually near utricule 4606, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at this two conduits, as discussed in his place of this description during support launches.

Second conduit 4630 comprises elongated axostylus axostyle 4632, and being provided with near the distal end of elongated axostylus axostyle 4632 can radial dilatation utricule 4640.There is nearly portion 4622, the support 4642 of distal part 4614 and side opening 4620 is arranged on utricule 4640.Distal part 4614 pressure holds utricule 4640, and to prevent from ejecting in course of conveying, and nearly portion 4622 partly press and holds utricule 4640, thus elongated axostylus axostyle 4604 can advance slidably or retraction below the nearly portion 4622 of support 4642.Support preferably can have the length of mating with the active length of utricule, or stent length comparable utricule active length is short.Distad offseting relative to utricule 4640 and support 4642 at least partially of utricule 4606, to make the profile of device minimum.In this embodiment, support 4642 preferably launches in the main split of vascular, although it also can launch in the branch of side.Second conduit 4630 is the rapid-exchange catheter (RX) with guidewire lumen 4634, this guidewire lumen extends to nearside guide line port 4636 from the distal guide line cap 4638 of elongated axostylus axostyle 4632 distal end, this nearside guide line port than the proximal end of conduit axostylus axostyle 4632 closer to distal port 4638.Preferably for the connector 4644 of luer connector element is connected to the proximal end of elongated axostylus axostyle 4632, and pressurizing device or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 4632, with inflation utricule 4640.Contribute to keeping conduit 4602,4632 parallel and prevent from tangling below the nearly portion 4622 part for axostylus axostyle 4604 being arranged on support 4608 during carrying and when axostylus axostyle 4604 advances slidably relative to axostylus axostyle 4632 or retracts.First conduit 4602 also can advance slidably or retract below the nearly portion 4622 of support 4642, thus axostylus axostyle 4604 is through the side opening 4620 in support 4642.Radiopaque labelling can be positioned over the diverse location on axostylus axostyle 4632, usually near utricule 4640 or support 4642, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at this two conduits, as discussed in his place of this description during support launches.

Figure 42 illustrates another exemplary embodiment of stent delivery system 4700.Stent delivery system 4700 comprises the first conduit 4702 and the second conduit 4730.First conduit 4702 comprises elongated axostylus axostyle 4704, and be provided with near the distal end of elongated axostylus axostyle 4704 can radial dilatation utricule 4706.There is nearly portion 4722, the support 4708 of distal part 4714 and side opening 4720 is arranged on utricule 4706.Distal part 4714 pressure holds utricule 4706, and to prevent from ejecting in course of conveying, and nearly portion 4722 partly presses and holds utricule 4706, thus the second conduit 4730 can advance slidably below the nearly portion 4722 of support 4708.First conduit is the rapid-exchange catheter (RX) with guidewire lumen 4712, this guidewire lumen extends to nearside guide line port 4711 from the distal guide line cap 4710 of elongated axostylus axostyle 4704 distal end, this nearside guide line port than the proximal end of conduit axostylus axostyle 4704 closer to distal port 4710.Connector 4716 connects with the proximal end of elongated axostylus axostyle 4704.Connector 4716 is preferably luer connector element, and this permission connects with pressurizing device or other device with inflation utricule 4706 easily.Radiopaque labelling can be positioned over the diverse location along axostylus axostyle 4704, usually near utricule 4706 and/or support 4708, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at two conduits during support launches, as discussed in his place of this description.

Second conduit 4730 comprises elongated axostylus axostyle 4732, and being provided with near the distal end of elongated axostylus axostyle 4740 can radial dilatation utricule 4732.The portions of proximal of utricule 4740 can be advanced slidably via side opening 4720 or retracts, as discussed below below the portions of proximal 4722 of support 4708.This allows the portions of proximal 4722 of support 4708 when utricule 4740 is expanded to expand.Distad offseting relative to utricule 4706 and support 4708 at least partially of utricule 4740, to make the profile of device minimum.In this embodiment, support 4708 preferably launches in the main split of vascular, although it also can launch in the branch of side.Second conduit 4730 is the rapid-exchange catheter (RX) with guidewire lumen 4734, this guidewire lumen extends to nearside guide line port 4736 from the distal guide line cap 4738 of elongated axostylus axostyle 4732 distal end, this nearside guide line port than the proximal end of conduit axostylus axostyle 4732 closer to distal port 4738.Preferably for the connector 4744 of luer connector element is connected to the proximal end of elongated axostylus axostyle 4732, and pressurizing device or other device is allowed to connect with the inflation lumen (not shown) in elongated axostylus axostyle 4732, with inflation utricule 4740.Contribute to keeping conduit 4702,4732 parallel and prevent from tangling below the nearly portion 4722 part for axostylus axostyle 4732 being arranged on support 4708 during carrying and when axostylus axostyle 4732 advances slidably relative to axostylus axostyle 4704 or retracts.Second conduit 4730 also can be advanced slidably or retract below the nearly portion 4722 of support 4708, to make axostylus axostyle 4732 through the side opening 4720 in support 4708.Radiopaque labelling can be positioned over the diverse location on axostylus axostyle 4732, usually near utricule 4740 or support 4742, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at this two conduits, as discussed in his place of this description during support launches.

Figure 43 illustrates another embodiment of stent delivery system 4800.Stent delivery system 4800 comprises the first conduit 4802 and the second conduit 4830.First conduit 4802 comprises elongated axostylus axostyle 4804, and be provided with near the distal end of elongated axostylus axostyle 4804 can radial dilatation utricule 4806.There is nearly portion 4822, the support 4808 of distal part 4814 and side opening 4820 is arranged on utricule 4806.Distal part 4814 pressure holds utricule 4806, and to prevent from ejecting in course of conveying, and nearly portion 4822 partly presses and holds utricule 4806, thus the second conduit 4830 can advance slidably below the nearly portion 4822 of support 4808.First conduit is the conduit being enclosed within (OTW) on guide line, this conduit has guidewire lumen 4812, and this guidewire lumen extends to the Y shape adapter 4814 with connector 4816 from the distal guide line cap 4810 of elongated axostylus axostyle 4804 distal end to the proximal end of elongated axostylus axostyle 4804.Connector 4816 is preferably Rule (Luer) connector, and this allows convenient connection syringe or other device for carrying out inner chamber flushing or inject contrast.When not connecting, guidewire lumen 4812 is drawn via connector 4816.Also be preferably that the second connector 4818 of luer connector element allows pressurizing device or other device to be attached to conduit, with via the inflation lumen (not shown) inflation utricule 4804 in elongated axostylus axostyle 4806.Radiopaque labelling can be positioned over the diverse location along axostylus axostyle 4804, usually near utricule 4806 and/or support 4808, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at two conduits during support launches, as discussed in his place of this description.

Second conduit 4830 comprises elongated axostylus axostyle 4832, and being provided with near the distal end of elongated axostylus axostyle 4832 can radial dilatation utricule 4840.The portions of proximal of utricule 4840 via side opening 4820, and can be advanced slidably or retracts, as discussed below below the portions of proximal 4822 of support 4808.Thus, the inflation of utricule 4840 also will make the portions of proximal 4822 of support 4808 expand.Distad offseting relative to utricule 4806 and support 4808 at least partially of utricule 4840, to make the profile of device minimum.In this embodiment, support 4808 preferably launches in the main split of vascular, although it can also launch in the branch of side.Second conduit 4830 is the conduits being enclosed within (OTW) on guide line, this conduit has guidewire lumen 4834, and this guidewire lumen extends to the Y shape adapter 4846 with connector 4848 from the distal guide line cap 4838 of elongated axostylus axostyle 4832 distal end to the proximal end of elongated axostylus axostyle 4832.Connector 4848 is preferably Rule (Luer) connector, and this allows convenient connection syringe or other device for carrying out inner chamber flushing or inject contrast.When not connecting, guidewire lumen 4834 is drawn via connector 4848.Also be preferably that the second connector 4844 of luer connector element allows pressurizing device or other device to be attached to conduit, with via the inflation lumen (not shown) inflation utricule 4840 in elongated axostylus axostyle 4832.Contribute to keeping conduit 4802,4830 parallel and prevent from tangling below the nearly portion 4808 part for axostylus axostyle 4832 being arranged on support 4822 during carrying and when axostylus axostyle 4832 advances slidably relative to axostylus axostyle 4804 or retracts.Second conduit 4830 also can advance slidably or retract below the nearly portion 4822 of support 4808, to make axostylus axostyle 4832 through the side opening 4820 in support 4808.Radiopaque labelling can be placed on the diverse location along axostylus axostyle 4832, usually near utricule 4840, to contribute to proximal end and the distal end of labelling support or utricule and to be convenient to aim at this two conduits, as discussed in his place of this description during support launches.

In any embodiment disclosed herein, business can be buied conduit and business and can be buied support and can mate to form shown system.In other embodiment, it is disposable apparatus for the treatment of single vascular that business can buy conduit, and can various combinations matches together and be linked together with polymer sleeve pipe.Operator selects two conduits for the anatomical structure of patient, then distally end by the polymer sliding sleeve of bushing of certain size on two conduits.Once conduit is aimed at by operator, then polymer sleeve pipe available heat sources or light source process are shunk to make two conduits and are combined by two pipe friction.Polymer sleeve pipe is by making by the typical polymers that can be used as contracting parcel post when thermal source or light source process.The polymer of polymer sleeve pipe such as can use polyolefin (chemical substance for the manufacture of contracting parcel post) to manufacture.Polymer sleeve pipe can not be cross-linked or covalently be attached to conduit, and several polymer is that business is commercially available and have required characteristic, thin, firm, non-caked and be 10 minutes or shorter with the response time in its source.Usual 15 centimeter length of polymer sleeve pipe, and there is various diameter to adapt to the typical catheter diameter of 4 French to 20 French.Operator by applying light pressure to test the conservation degree of bonding before process.If polymer sleeve pipe does not tightly keep, operator selectable is selected and is used the polymer sleeve pipe of more minor diameter or by by placed adjacent one another for polymer sleeve pipe and use more than one polymer sleeve pipe.Or, several more small casings of length 1 to 10 centimetre can be placed on several diverse locations of conduit.

In any embodiment discussed herein, therapeutic agent can be arranged on target treatment support or utricule being eluted to also controlling such as stenotic lesion portion from it.Exemplary treatment agent contributes to suppressing restenosis, hypertrophy or having other treatment advantage.Exemplary anti-proliferative agent comprises the antitumor drug of such as paclitaxel, methotrexate and batimastat (batimastal) and so on; Such as doxycycline, tetracycline, rapamycin, everolimus, the antibiotic of the sum analogous to general Dedekind sum and actinomycin and so on of Pai Ermosi (biolimusA9), Nuo Womosi (novolimus), Mai Ermosi (myolimus), Zuo Tamosi and other rapamycin; The amino inhibitor of such as dexamethasone and dehydrogenation cortex (steroid) alcohol; The such as nitric oxide source of Nitroprusside (nitroprussides); Estrogen; Estradiol; And analog.Well known to those skilled in the art for applying the method for therapeutic agent to support or utricule, and described by having had in patent and scientific literature.

support is carried:

Figure 25 A-30B illustrates the exemplary transport order of preferred embodiment in eight steps.Step 1 illustrates and 0.035 inch of guide line is incorporated into furcation always.Step 2 illustrates the follow-up of guide catheter on guide line.Step 3 illustrates the placement location with guide catheter that removes of guide line.Step 4 illustrates the follow-up and the placement that exchange fast in sub-vascular and be enclosed within the compatible guide line on guide line in compatible guide line and mother lode pipe.Step 5A & 5B illustrates that conduit system distally follows up on two guide lines.Step 6A illustrates the local expansion of the inflation of ascus body and the placement of submounts and female support.Step 6B illustrates that the inflation of mother cyst body is to be placed on the distal part of female support in mother lode pipe.Step 7A illustrates that in main split, female support makes its side opening towards sub-vascular.Step 7B illustrates that branch stent is positioned partially in sub-vascular and subsystem oral area is opened completely and proceeded on mother lode pipe.

In alternative embodiments, delivery conduit mother cyst body has tapering point to adapt to have utricule and the support of non-uniform profile.Such as, the proximal end of sub-vascular stent can be designed to have the girth larger than distal end to meet natural bifurcated anatomical structure.Sub-vascular utricule can have taper equally to make support suitably expand and to guarantee complete juxtaposition.In addition, female support Design can be become expand along its profile differences the comparatively large artery trunks diameter meeting knuckle or oral area place.In other words, proximal end and the distal end girth of mother lode pipe utricule and mother lode pipe holder are less, and the central part branch of mother lode pipe holder has larger girth.In alternative embodiments, mother lode pipe utricule has tapering point to adapt to distally balloon catheter part and guidewire lumen.In addition, mother lode pipe utricule is expanded to adapt to native vessel anatomical structure with can being designed to difference.

In the preferred embodiment, distally (son) balloon catheter part is pressed and is possessed half support in rapid-exchange catheter.Sub-vascular stent is about 4-20 centimeter length, and sub-vascular utricule about two double-length.Mother lode pipe holder is about 10-30 centimeter length, and difference ground pressure holds to allow ascus body canal part independent operation.The distal part pressure of mother lode pipe holder is held enough tight to prevent whole support from surprisingly offseting at intra-operative.It is appropriate enough tight that the nearly portion pressure of mother lode pipe holder holds ground, with reduce cross section and allow ascus body canal part relative to mother cyst body canal part distad or nearside move.Nearside (mother) balloon catheter part is enclosed within guide line to design, and mother lode pipe utricule is preferably sub-vascular utricule nearside about 3 centimetres.In alternative embodiments, support Design becomes to allow the middle part of support to expand relative to proximal end and distal end difference.Specifically, the bifurcated lesions portion that this design is convenient in support leap mother lode pipe places, because it has the girth larger than end at middle part compared with the support with constant profile.In addition, this profile may be adjusted to the nearside or the distally that make maximum girth can be placed on support mid point.In this particular example, the distally that maximum girth is put in the bracket, but can be reverse easily for variable patient anatomical structure.Local pressure is held has following characteristics, makes it possible to keep enough support retentivitys between conveying and resting period, and still allows level two to have controllability and conveying capacity.

Figure 31 illustrates that the part pressure before being placed on any balloon catheter holds bifurcated stent.Figure 32-34 illustrates embodiments of the invention with three steps.First, bifurcated stent is partly pressed and is held in female catheter balloons on about 1/3rd of its distal part, and sub-conduit is loaded by female conduit and female support, and wherein submounts can be pressed individually and be held.The second, submounts is held by pressure and proximad retracts submounts proximal end to be aligned near female support distal end.3rd and last, the nearly portion of female support can be held with reduced outside diameter by pressure; Two stands is still also allowed relative to each other to move.

Figure 35 illustrates the cross section of mother cyst body canal and the ascus body canal system without submounts.Sub-conduit is at female conduit top.Female conduit is differentially pressed around female catheter balloons and sub-conduit and is held, because sub-conduit profile is less than female conduit.Difference pressure is held be uneven and can be formed various shape of cross section with adapt to different catheter design, utricule design and support Design.Such as, pyriform or numeral 8 are possible structures.Present example is designed to reduce profile as far as possible.In a better manufacture method, protective casing is placed between two conduits.Protective casing only needs to cover the part that can contact during pressure holds process, then dismountable protective casing.

Figure 36 illustrates and is arranged on female support in female catheter balloons and by the side view of female support installing at the supravasal sub-conduit of mother.The distal part of female support will be pressed at the standard conditions and be held support to be fixed firmly to mother cyst body and female conduit.The nearly portion of female support is partly held to reduce profile by pressure; But still allow sub-conduit relative to female conduit proximad or distally freely-movable.This embodiment illustrate support circumferentially with longitudinal difference held by pressure.The pressure amount of holding will be determined by support Design and number, conduit size and utricule size; Therefore pressure holds longitudinally axis is differentiated.

Figure 37 illustrates and is arranged on female support in female catheter balloons and by the side view of female support installing at the supravasal sub-conduit of mother.Submounts also comprises can press the support held at the standard conditions.The distal part of female support will be pressed at the standard conditions and be held support to be fixed firmly to mother cyst body and female conduit.In an experiment, this layout is tested and holds intensity with the distally being determined female support by proximad rock conduit and support pressure; Result is that sub-conduit successfully passes and presses female support of holding and still well keep submounts.Can further feature be utilized during pressure holds process, such as slight internal positive pressure be increased to utricule, make final utricule surface rest the head on out the external diameter about 0.002 inch of support.This process can form the design that protective cradle avoids coordinating with vascular, therefore reduces friction and improves support retentivity simultaneously.

In addition, this process modification safety also reduces the damage to vascular.Although above-described embodiment discloses at its half portion far away or the bifurcated stent held around its half portion pressure far away; But this is not restriction.This support can be pressed by different way along its axis according to support Design and be held; If the Kong Wei of such as side face is along axis centering.Preferably the distally of bifurcated stent may be made to press and to hold the distally, hole partly just extending to sub-conduit and pass.Or distally pressure is held part and can partially or even wholly be extended on the hole that sub-conduit passes.

Figure 38 A-38M illustrates another illustrative methods of process furcation.The method is similar to those previously described methods, and main difference is only to carry single support.In other embodiments, two supports are carried.

In Figure 38 A, bifurcated vascular BV comprises side branch vessel SB and main split vascular MB.Main split has main split pathological changes portion ML, and side branch has side branch pathological changes portion SL.Angle between side branch and main split is called angle of forking, and is represented by θ.At Figure 38 B, guide catheter 4002 distad advances in vascular, until it is adjacent with pathological changes portion ML, SL with furcation.First guide line GW1 distad advances in main split MB, until it is in ML distally, pathological changes portion of main split.Second guide line is also distad advanced, until its approaching side branch SB and be positioned at the distally of side branch pathological changes portion SL.

In figure 38 c, the processing system with the first conduit 4004 and the second conduit 4024 is distad advanced towards furcation by guide catheter 4002.Two conduits 4004,4024 can advance independently of one another, or two conduits can preferably advance simultaneously.First conduit 4004 comprises elongated axostylus axostyle 4006, and the distal part of elongated axostylus axostyle 4006 has can radial dilatation utricule 4008.Utricule 4008 has portions of proximal 4010 and distal part 4014.The radiopaque labelling 4016 of the radiopaque labelling of nearside 4012 and distally can be used for the proximal end and the distal end that contribute in fluoroscopy or other method for visualizing, determine utricule 4008.Soft polymer tip 4018 can be used on the distal part of conduit axostylus axostyle 4006, to prevent from causing wound to vascular during carrying, and conduit axostylus axostyle 4006 has distal guide line cap 4020 enters or leave guidewire lumen (not shown) in conduit axostylus axostyle 4006 to allow guide line GW1.First conduit 4004 can have and exchanges structure fast, or is enclosed within the structure on guide line.Second conduit 4024 comprises elongated axostylus axostyle 4026, and this elongated axostylus axostyle has on its distal part can radial dilatation utricule 4028.First utricule 4008 is in the distally of the second utricule 4028.The axial dipole field of this utricule contributes to making the profile of system to reduce to minimum.Support 4034 is arranged on the second utricule 4028.Stent length roughly can be mated with the active length of utricule, or can be shorter.In this embodiment, the length of support 4034 is less than the active length of utricule 4028.The portions of proximal 4010 of utricule 4008 can be retracted slidably below the portions of proximal of support 4034, and the inflation of utricule 4008 is expanded making the portions of proximal of support 4034.A part for first elongated axostylus axostyle 4006 is arranged on below the nearly portion of the second support 4034, and support 4034 also has side opening 4036, thus the first elongated axostylus axostyle 4006 can pass this side opening.First elongated axostylus axostyle 4006 can slide relative to the second elongated axostylus axostyle 4026 below support 4034.Previous with see mode include herein U.S. Patent application in disclose support pressure in more detail and hold.Second conduit axostylus axostyle 4026 also comprises the radiopaque labelling 4040 of the radiopaque labelling of nearside 4032 and distally, and they contribute to identifying the proximal end of utricule 4028 and the proximal end of distal end and support 4034 and distal end.Second conduit 4024 also has soft polymer tip 4042, during it contributes to making conveying, the wound of vascular is minimized, and distal guide line cap 4044 allows guide line GW2 insert or leave from the guidewire lumen (not shown) in elongated axostylus axostyle 4026.Second conduit can have the structure exchanging structure fast or be enclosed within guide line.

In Figure 38 D, two conduits 4004,4024 are distad advanced further towards furcation, until the first utricule 4008 is positioned in the main split MB in the oral area distally of side branch SB, and support 4034 to be partly arranged in side branch SB, adjacent with side branch pathological changes portion SL, and support 4034 to be also arranged on main split MB interior, adjacent with main split pathological changes portion ML.Side opening 4036 is also roughly towards the direction of main split vascular MB.The advance of two conduits is preferably carried out simultaneously, but they also can be advanced independently of one another.Operator can feel opposing conduit 4004,4024 resistance of advancing further, because when conduit is distad advanced further, two conduit axostylus axostyles 4006,4026 relative to each other separate because they are forced to the knuckle against bifurcated.But a part for the first elongated axostylus axostyle 4006 is arranged on the part below of the second support 4034, and therefore two axostylus axostyles 4006,4026 only can separate so far away.Therefore, when operator feels the resistance that opposing conduit axostylus axostyle is advanced further, operator knows that two conduits 4004,4024 and associated supports and utricule thereof are suitably located relative to furcation.

In Figure 38 E, the first conduit 4004 is retracted relative to the second conduit 4024 proximad.Because a part for the first conduit axostylus axostyle 4006 is arranged on the part below of the second support 4034, so the first axostylus axostyle 4006 is retracted in side opening 4036 slidably, and the first axostylus axostyle 4006 is also retracted slidably in the part below of support 4034.First axostylus axostyle proximad is retracted, till do not aim at thoroughly by radiation labelling 4032 with nearside for the radiopaque labelling 4012 of nearside, thus, the portions of proximal of utricule 4008 is arranged on below support 4034, and the distal part 4014 of the portions of proximal 4010 of utricule 4008 and utricule 4008 keeps not retraining by support 4034.Utricule 4008 is arranged from side opening 4036 to the proximal end of support 4034 below support 4034.Support 4034 is disposed adjacent with side branch pathological changes portion SL and main split pathological changes portion ML, and side opening 4036 and main split vascular MB coarse alignment.

In Figure 38 F, utricule 4008 carrys out radial dilatation by contrast medium, saline or its combination usually, becomes to coordinate with the wall of main split pathological changes portion ML and main split thus by a part of radial dilatation be arranged on utricule of support 4034.The distal part of support 4034 is stayed in the side branch SB that substantially do not expand.The inflation of utricule 4008 also makes side opening 4036 expand and side opening 4036 is aimed at main split.

In Figure 38 G, utricule 4008 shrinks, and then in Figure 38 H, another utricule 4028, by the expansion of contrast medium, saline or its combined radial, makes support 4034 radial dilatation further thus.The expansion of utricule 4028 makes the distal part of support 3934 expand into coordinate with side branch vessel wall and side branch pathological changes portion SL.The nearly portion of support 3934 and side opening 3936 also can be expanded further and aim at main split.

Now see Figure 38 I, utricule 4028 shrinks, and then two utricules " interface utricule " technology inflation simultaneously, as shown in Figure 38 J.Two utricules 4008,4028 carry out inflation by contrast medium, saline or its combination, until they are fitted to each other and expand completely in main split MB and side branch SB.Interface utricule technology guarantee support 4034 expand completely and with the complete juxtaposition of blood vessel wall and pathological changes portion.Therefore, the portions of proximal of support 4034 expands into and coordinates to main split's blood vessel wall and relevant pathological changes portion ML, and the distal part of support 4034 expands into and coordinates to side branch vessel wall and relevant pathological changes portion SL.Additionally, interface utricule technology guarantees that side opening 4036 is expanded completely and aims at the main split in furcation downstream.Therefore, exist from main split to side branch and smoothly transitting through furcation.In addition, interface utricule technology guarantees that side opening does not block the blood flow that main split or interference flow through furcation.

In Figure 38 K, two utricules 4008,4028 shrink, and in Figure 38 L, two conduit 4004,4024 proximads shrink.Conduit can or be retracted independently of one another simultaneously.First conduit 4004 is by the side opening 4036 in support 4034 and retract below the portions of proximal of support 4034.Second conduit 4024 is retracted by whole support 4034.Two conduits 4004,4024 and guide catheter 4002 and two guide line GW1, GW2 are removed in Figure 38 M.Support 4034 keeps being implanted in furcation place.Alternatively, support can comprise all therapeutic agents as discussed previously, and they can be eluted in pathological changes portion by controllable rate, to contribute to preventing restenosis.

Above-mentioned any method can use any support disclosed herein in described any system construction.In addition, previously described any feature can also be used above.Therefore, person of skill in the art will appreciate that and can form any amount of combination.Such as, conduit system can have any combination exchanging fast or be enclosed within and guide line constructs, there is any support disclosed herein, have or not there is therapeutic agent, and there is or do not have any hollow switching port, capture duct, detachable capture duct or above-mentioned card accessory.

support:

Conduit system as herein described and method can use the commercially available support of business to be used as proximal stent or the distal stent of system.When business can buy support for distal stent, it only needs pressure to hold distally balloon catheter.When business can buy support for proximal stent, it partly can be pressed and hold nearside utricule, and a part for the second conduit axostylus axostyle is mounted slidably below support, and a part for the second conduit axostylus axostyle is slidably through the side opening in support.Support pressure holds nearside utricule, thus not from utricule displacement during carrying, and make the second conduit axostylus axostyle can in this support slid underneath in addition.Figure 39 A-39H illustrates and can be used for several examples that above-mentioned conduit system structure and method itself or the business of retrofiting a little can buy support.Such as, Figure 39 A illustrates AbbottVascular bracket for eluting medicament 4102a.A part for conduit axostylus axostyle can pass its center channel setting below support, and conduit can leave the side opening in support.Side opening can be formed in the gap 4106a between gap 4104a between unit (cell) interior adjacent supporting piece or axial adjacent cells.Figure 39 B illustrates Cordis support 4102b.A part for conduit axostylus axostyle can pass its center channel setting below support again, and conduit can leave the side opening in support.Side opening can be formed in the gap 4106b between gap 4104b in unit between adjacent supporting piece or axial adjacent cells.Figure 39 C illustrates BostonScientific support 4102c.A part for conduit axostylus axostyle can pass its center channel setting below support, and conduit can leave the side opening in support.Side opening can be formed in the gap 4106c between gap 4104c in unit between adjacent supporting piece or axial adjacent cells.Figure 39 D illustrates Medtronic support 4102d.A part for conduit axostylus axostyle can pass its center channel setting below support, and conduit can leave the side opening in support.Side opening can be formed in the gap 4106d between gap 4104d in unit between adjacent supporting piece or axial adjacent cells.Figure 39 E illustrates Palmaz- support 4104e.A part for conduit axostylus axostyle can pass its center channel setting below support, and conduit can leave the side opening in support.Side opening can be formed in the gap 4106e between gap 4104e in unit between adjacent supporting piece or axial adjacent segment.Other support Design has the side opening specifically for processing furcation.These supports also can be used for the system and method disclosed herein.Such as, Figure 39 F-39H illustrates and comes from BostonScientific(Boston science) several stent embodiment, and at United States Patent (USP) the 7th, in 678, No. 142, have detailed disclosure.Figure 39 F illustrates the expansion with side opening 4106f and support 4102f after leveling.Figure 39 F illustrates bracket geometry (plane graph of expansion), and wherein support member forms side opening 4106f, and this side opening allows sensible side branch, and can hold hereinbefore conduit axostylus axostyle.Side opening is formed by space 4104f, the 4108f between support member.Figure 39 G illustrates another bracket geometry (plane graph of expansion) with side opening 4106g.Or side opening is formed by space 4104g, the 4108g between support member or axial connecting part.Figure 39 H illustrates another bracket geometry (plane graph of expansion) with side opening 4106h.Side opening can be formed by the space between support member 4104h or axial connecting part 4108h.In any embodiment in these embodiments, conduit axostylus axostyle can be slidably disposed on the part below of support, and conduit axostylus axostyle can leave side opening.In addition, any support disclosed herein can deliver all therapeutic agents as described above and carry out local drug delivery.In addition, although to be preferably utricule distensible for support as herein described, person of skill in the art will appreciate that, also can use self expandable and mixing utricule expansible/from-expandable stent.

utricule constructs:

Described herein for making the utricule of support radial dilatation can be the cylindrical utricule along active length with constant diameter, or diameter can change.When to tapered pulse tube mounting bracket, maybe advantageously use utricule, this utricule has the variable-diameter utricule of more tight fit vascular anatomy.Such as, in Figure 44 A, taper utricule 5006 is attached to the distal part of axostylus axostyle 5002.Soft tip 5004 prevents from causing wound to vascular during carrying.Utricule is tapered, makes the nearly portion 5010 of utricule have the diameter larger than distal part 5006.Any tapering can be used.Figure 44 B illustrates another embodiment of the utricule 5012 with multiple stepped region 5014.These stepped region can have the increment of any amount, and in the preferred embodiment, the nearly portion 5016 of utricule has the diameter larger than distal part 5018.Any embodiment of these embodiments or its combination can be used for system and method as herein described to process furcation.Use taper or stepped utricule to allow stent-expansion to become to mate blood vessel wall more closely, the nearly portion of the support wherein expanded has the diameter larger than the distal part of support.

Except use has the conduit and taper or stepped utricule exchanging or be enclosed within guidewire lumen on guide line fast, balloon catheter always can not adopt guidewire lumen.But, fixing guide line can be attached to the distal end of conduit.Such as, Figure 45 illustrates the exemplary embodiment of fixing guide line conduit 5102, and fixing guide line conduit 5102 has the utricule 5106 of the distal part being attached to axostylus axostyle 5104.A part for guide line 5108 is attached to the distal end of conduit regularly, and this fixing guide line contributes to conduit follow-up passes through vascular.Fixing guide line can have any amount of shape, comprises straight line, curve, J-shaped tip etc.This embodiment can be used for any system and method disclosed herein, and it can have or not have the support that pressure holds utricule.Fixing guide line conduit can be used in main split, or more preferably it can be used in the branch of side.

Although be more than the complete description of present pre-ferred embodiments, also various alternative, remodeling or equivalent can be used.Therefore, above-mentioned description should not thought to limit the scope of the present invention be defined by the appended claims.

Claims

1., for the treatment of a system for furcation, described system comprises:

First delivery conduit, described first delivery conduit comprises the first elongated axostylus axostyle and first expandable members adjacent with the distal end of described first elongated axostylus axostyle with nearside and distal end; And

Second delivery conduit, described second delivery conduit comprise the second elongated axostylus axostyle with nearside and distal end, second expandable members adjacent with the distal end of described second elongated axostylus axostyle and be arranged in described second expandable members can radial dilatation support

Wherein, described support comprises sidewall, described sidewall has the side opening through it, and described support has the collapsed configuration and expanded configuration that are suitable for being transported to described furcation, under described expanded configuration, described support supports the wall of the wall of the main split of described furcation and the side branch of described furcation

Wherein, the Part I of described first elongated axostylus axostyle is arranged on below the portions of proximal of described support, and described first elongated axostylus axostyle is through described side opening, be arranged in the distal part of described support to make the Part II of described first elongated axostylus axostyle, and when described support is in described collapsed configuration, described first elongated axostylus axostyle can slide axially relative to described second elongated axostylus axostyle

Wherein, described first expandable members can be axially spaced with described second expandable members, to make described first expandable members in the distally of described second expandable members, and

Wherein, described support is pressed unevenly and is held described second expandable members and make:

A () is when described support is in collapsed configuration, the nearly portion of described support adapts to described first expandable members and moves to a position relative to described support towards nearly portion, in described position, a part for described first expandable members is positioned at below described support, and described first expandable members can be expanded, to expand the nearly portion of described support, and

B the distal part pressure of () described support is held described second expandable members and is removed from described second expandable members due to the described movement towards nearly portion of described first expandable members to prevent described support.

2. the system as claimed in claim 1, is characterized in that, described first expandable members and described second expandable members can be expanded independently of one another.

3. the system as claimed in claim 1, is characterized in that, described first expandable members or described second expandable members comprise utricule.

4. the system as claimed in claim 1, is characterized in that, distal expandable element cross-section profile is less than the cross-sectional profiles of another expandable members.

5. the system as claimed in claim 1, is characterized in that, one of described first elongated axostylus axostyle or described second elongated axostylus axostyle comprise the region with guidewire lumen, inflation lumen and exchange inner chamber,

Another elongated axostylus axostyle is slidably disposed in described exchange inner chamber, and

Expandable members on another elongated axostylus axostyle described with to have the elongated axostylus axostyle of described exchange inner chamber axially spaced, to make described expandable members on another axostylus axostyle described in the distally being positioned at the described expandable members on the described elongated axostylus axostyle with described exchange inner chamber.

6. the system as claimed in claim 1, is characterized in that, described support can balloon dilatation.

7. the system as claimed in claim 1, it is characterized in that, also comprise therapeutic agent, described therapeutic agent is arranged on and described can on radial dilatation support or is arranged in one of described first or second expandable members, described therapeutic agent be suitable for from described can one of radial dilatation support or the described first or second expandable members eluting.

8. system as claimed in claim 7, it is characterized in that, described therapeutic agent comprises anti-restenosis agent.

9. the system as claimed in claim 1, it is characterized in that, described first elongated axostylus axostyle comprises setting the first radiopaque labelling thereon, and described second elongated axostylus axostyle comprises setting the second radiopaque labelling thereon, thus, when described first radiopaque labelling and described second radiopaque markers align, the operate portions of described first expandable members is aimed at the operate portions of described second expandable members.

10. system as claimed in claim 9, it is characterized in that, when described first radiopaque labelling and described second radiopaque markers align, a part for described first expandable members is arranged on below described support, thus, the expansion of described first expandable members also will make a part for described support expand.

11. systems as claimed in claim 9, it is characterized in that, described first expandable members or described second expandable members comprise active length, and described active length comprises conical region, and the diameter of the portions of proximal of described conical region is greater than the diameter of the distal part of described conical region.

12. the system as claimed in claim 1, is characterized in that, described first expandable members or described second expandable members can be expanded, to make the diameter of the portions of proximal of differential expansion larger than the diameter of the distal part of differential expansion differentially.

13. the system as claimed in claim 1, is characterized in that, described support can be expanded differentially, and to make under described expanded configuration, the diameter of the Part I of described support is larger than the diameter of the Part II of described support.