CN102875663B - Purification method of lixisenatide - Google Patents

Purification method of lixisenatide Download PDF

Info

Publication number
CN102875663B
CN102875663B CN201210363634.4A CN201210363634A CN102875663B CN 102875663 B CN102875663 B CN 102875663B CN 201210363634 A CN201210363634 A CN 201210363634A CN 102875663 B CN102875663 B CN 102875663B
Authority
CN
China
Prior art keywords
phase
mobile phase
performance liquid
lixisenatide
liquid chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201210363634.4A
Other languages
Chinese (zh)
Other versions
CN102875663A (en
Inventor
覃亮政
刘建
马亚平
袁建成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hybio Pharmaceutical Co Ltd
Original Assignee
Hybio Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybio Pharmaceutical Co Ltd filed Critical Hybio Pharmaceutical Co Ltd
Priority to CN201210363634.4A priority Critical patent/CN102875663B/en
Publication of CN102875663A publication Critical patent/CN102875663A/en
Application granted granted Critical
Publication of CN102875663B publication Critical patent/CN102875663B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links