CN102872343A - Nursing hydropathic compress liquid for promoting recovery of nerve injury - Google Patents
Nursing hydropathic compress liquid for promoting recovery of nerve injury Download PDFInfo
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Abstract
The invention discloses nursing hydropathic compress liquid for promoting recovery of nerve injury, and aims at solving problem of peripheral nerve injury. The nursing hydropathic compress liquid is characterized by being processed by a plurality of Chinese medicaments, and comprises the following raw materials in parts by weight: 6 to 10 parts of indian iphigenia bulb, 8 to 15 parts of weeping forsythiae capsule, 8 to 15 parts of climbing fig, 6 to 10 parts of psychotria serpens, 6 to 10 parts of pangolin, 8 to 15 parts of Chinese angelica, 6 to 10 parts of selfheal spike, 8 to 15 parts of clove oil, and 3 to 6 parts of folium eucalypti. Clinical tests prove that the nursing hydropathic compress liquid has the characteristics of good curative effect and high safety in treating peripheral nerve injury, and is worthy of clinical application and popularization.
Description
Technical field
The present invention relates to neurosurgery medicaments nursing field, be specifically related to a kind of nursing soak liquid of repairing after the nerve injury of promoting.
Background technology
Peripheral nerve injury refers to that peripheral nerve is done or its branch is subject to extraneous directly or indirectly strength effect and the damage that occurs, is a kind of common neurosurgery related disease.Typical case's performance after the damage: the dyskinesia, sensory disturbance and dysautonomia.Common peripheral nerve injury has: brachia plexus injury, injury of radial nerve, radial nerve injury, median nerve injury, injury of tibial nerve, common peroneal nerve injury etc.Damage reason is cutting, tractive, extruding etc. more, can be divided three classes by degree of injury: 1. the neurapraxia nerve temporarily loses conduction function, degeneration does not occur in nerve fiber, the clinical manifestation dyskinesia is national and without amyotrophy, hypalgesia and not disappearing is such as tourniquet paralyses in the art.2. neural axis interruption nerve is subjected to management of blunt injuries or decompression, axonotmesis causes axon and the myelin generation degeneration of far-end, endoneurial tube is complete, axon can enter the end slightly along the Schwann sheath pipe range, clinical manifestation is this nerve distribution area motion, sensory function forfeiture, and amyotrophy and neurotrophy sexually revise.3. the neurotmesis nerve ruptures fully, and function of nervous system completely loses, and needs the underwent operative reparation, can restore funcitons.
At present, neurosurgery for the Therapeutic Principle of peripheral nerve injury is: 1. with the method treatment neurotmesis of repairing; 2. remove the fracture end compressing with the method for decompression; 3. remove the cicatricial adhesion strangulation with the method for loosening; 4. take clamping plate or stent support for muscle and the joint in innervation zone, cooperate passive activity, recover limb function and range of motion with the method for taking exercise.
But there is following defective in above-mentioned therapeutic scheme: 1. clinically often expect autonomous recovery with nerve for the above-mentioned first kind and Equations of The Second Kind nerve injury, nerve recovery is slow, in case amyotrophy and fibrosis occur, the rehabilitation prognosis after then can greatly affecting; 2. take passive activity for the limb preservation function of joint great meaning to be arranged for the limbs nursing of innervation zone, but in the practical operation, because it is unbalance that limbs bend and stretch the both sides muscular strength, causes a pleural muscle meat stiff, easily causes muscle sprain in the passive activity nursing procedure; 3. in the nerve recovery process, teleneuron produces the serious sense of discomfort such as tingle swollen sometimes, and these senses of discomfort can not be alleviated by analgesics.
Chinese medicine nerve injury, decoction are oral with the benefiting QI and nourishing blood righting more, and topical application mostly is acupuncture, acupuncture and moxibustion therapy peripheral nerve injury curative effect certainly, but the acupuncture and moxibustion therapy patient suffering is large, and needs every day and goes to hospital, so easily gave up halfway affects the treatment.
Summary of the invention
Technical assignment of the present invention is for above the deficiencies in the prior art, provide a kind of can relaxed muscle, alleviate the teleneuron sense of discomfort, promote the nursing soak liquid repaired after the nerve injury, and the patient is acceptant.
The technical scheme that the present invention solves its technical problem is: a kind of nursing soak liquid of repairing after the nerve injury of promoting, it is characterized in that being processed by plurality of Chinese, its composition of raw materials and weight proportion are: 6 ~ 10 parts of Pseudobulbus Cremastrae Seu Pleioness, 8 ~ 15 parts of Fructus Forsythiaes, 8 ~ 15 parts of Caulis fici pumilae (Fructus Fici Pumilae)s, 6 ~ 10 parts of Ramulus et Folium Psychotriae Serpentis, 6 ~ 10 parts of Squama Maniss, 8 ~ 15 parts of Radix Angelicae Sinensis, 6 ~ 10 parts of Spica Prunellaes, 8 ~ 15 parts of Oleum Caryophyllis, 3 ~ 6 parts of Folium eucalypti globueli (Eucalyptus globulus Labill.)s.
Its optimum weight proportioning is: 8 parts of Pseudobulbus Cremastrae Seu Pleioness, 10 parts of Fructus Forsythiaes, 10 parts of Caulis fici pumilae (Fructus Fici Pumilae)s, 8 parts of Ramulus et Folium Psychotriae Serpentis, 8 parts of Squama Maniss, 10 parts of Radix Angelicae Sinensis, 8 parts of Spica Prunellaes, 10 parts of Oleum Caryophyllis, 5 parts of Folium eucalypti globueli (Eucalyptus globulus Labill.)s.
Wherein said: Pseudobulbus Cremastrae Seu Pleiones is orchid Cremastra appendiculata Cremastra appendiculata (D.Don) Makino, pleione bulbocodioides Pleione bulbocodioides(Franch.) the dry pseudobulb of Rolfe or Pleione yunnanensis Pleione yunnanensis Rolfe.Sweet, the little suffering of nature and flavor, cold.Enter liver, stomach warp.But the merit heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation.
Fructus Forsythiae is the fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.The nature and flavor toil is slightly cold.Enter the heart, gallbladder meridian.But merit heat-clearing and toxic substances removing.
Caulis fici pumilae (Fructus Fici Pumilae) is stem, the leaf of moraceae plants Caulis fici pumilae (Fructus Fici Pumilae) Ficus pumila L..Sour in the mouth, cool in nature.But merit expelling wind and removing dampness; Promoting blood circulation to remove obstruction in the collateral; Removing toxic substances and promoting subsidence of swelling.
Ramulus et Folium Psychotriae Serpentis is Maguireothamnus speciosus crawl branch, leaf or the Herb of Psychotria rubra (Lour.) Poir..The nature and flavor toil; Flat.Return liver; Heart channel.But merit wind-damp dispelling; Relaxing muscles and tendons and activating QI and blood in the collateral; Reducing swelling and alleviating pain.
Squama Manis is the scute of Manidae animal Squama Manis Manis pentadactyla Linnaeus.Nature and flavor are salty, are slightly cold.Return liver, stomach warp.The merit stimulating milk secretion of can stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.
Radix Angelicae Sinensis is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor are sweet, hot, temperature.Return liver, the heart, spleen channel.Merit can be enriched blood and be invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Spica Prunellae is the dry fruit ear of labiate Spica Prunellae Prunella vulgaris L..Nature and flavor are hot, bitter, and are cold.Return liver, gallbladder meridian.Merit can be relieved inflammation or internal heat, and makes eye bright eliminating stagnation, detumescence.
Oleum Caryophylli is plant clove of myrtaceae Syzygium aromaticum(L.) dry flower (Flos Caryophylli) of Merr. Et Perry is through the volatile oil of distillation gained.Acrid in the mouth, sweet, hot in nature.Return spleen, stomach, kidney channel.But the merit warming the stomach, the kidney warming.
Folium eucalypti globueli (Eucalyptus globulus Labill.) is the leaf of myrtle Eucalyptus globulus Labill Eucalyptus globulus Labill..Toil, cold.But merit dispelling wind to relieve the exterior syndrome; Heat-clearing and toxic substances removing; Phlegm-eliminiating and qi-regulating; Killing parasites for relieving itching.
Composition principle: repair after we's purpose relaxed muscle, alleviation teleneuron sense of discomfort, the promotion nerve injury, so select Pseudobulbus Cremastrae Seu Pleiones, Fructus Forsythiae heat-clearing and toxic substances removing eliminating stagnation, the inventor is the clinical experience gained for many years, the cool acrid in the mouth of this two flavors property of medicine, light clear floating is used for local performance of dispersing and is better than other heat-clearing and toxic substances removing medicines; Caulis fici pumilae (Fructus Fici Pumilae) expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances and promoting subsidence of swelling, Ramulus et Folium Psychotriae Serpentis wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain, inventor's clinical practice draws, and the two cooperation is better than the single medicinal material result of use for local muscular tone; Squama Manis detumescence collateral dredging; Chinese angelica blood supplementing is invigorated blood circulation, and can promote local microcirculation; The Spica Prunellae mass dissipating and swelling eliminating that relieves inflammation or internal heat in order to cooperating Pseudobulbus Cremastrae Seu Pleiones, Fructus Forsythiae, and has played the effect of tying-in; The Oleum Caryophylli extremely hot in nature can resist the stimulation that other the cold and cool medicines in the present invention's combination produce the part, and can promote local skin to the absorption of medicine; Inventor's experiment confirm, Folium eucalypti globueli (Eucalyptus globulus Labill.) adds the transdermal absorption factor that can promote all medicines in the decoct.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have preferably curative effect in described weight portion scope.
The specific embodiment
Below in conjunction with practical situation, the specific embodiment of the present invention is elaborated.
Embodiment 1, the crude drug weight proportion: Pseudobulbus Cremastrae Seu Pleiones 6g, Fructus Forsythiae 8g, Caulis fici pumilae (Fructus Fici Pumilae) 8g, Ramulus et Folium Psychotriae Serpentis 6g, Squama Manis 6g, Radix Angelicae Sinensis 8g, Spica Prunellae 6g, Oleum Caryophylli 8g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 3g.
Embodiment 2, the crude drug weight proportion: Pseudobulbus Cremastrae Seu Pleiones 10g, Fructus Forsythiae 15g, Caulis fici pumilae (Fructus Fici Pumilae) 15g, Ramulus et Folium Psychotriae Serpentis 10g, Squama Manis 10g, Radix Angelicae Sinensis 15g, Spica Prunellae 10g, Oleum Caryophylli 15g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 6g.
Embodiment 3, the crude drug weight proportion: Pseudobulbus Cremastrae Seu Pleiones 8g, Fructus Forsythiae 10g, Caulis fici pumilae (Fructus Fici Pumilae) 10g, Ramulus et Folium Psychotriae Serpentis 8g, Squama Manis 8g, Radix Angelicae Sinensis 10g, Spica Prunellae 8g, Oleum Caryophylli 10g, Folium eucalypti globueli (Eucalyptus globulus Labill.) 5g.
During use, Chinese medicine Pseudobulbus Cremastrae Seu Pleiones of the present invention, Fructus Forsythiae, Caulis fici pumilae (Fructus Fici Pumilae), Ramulus et Folium Psychotriae Serpentis, Squama Manis, Radix Angelicae Sinensis, Spica Prunellae, Folium eucalypti globueli (Eucalyptus globulus Labill.) are decocted with water twice, add Oleum Caryophylli behind the merging filtrate, use the gauze hot-wet compress, every day twice, each 30min.
Effective combination of said medicine is coordinated mutually, can effectively reach the purpose of repairing after relaxed muscle, alleviation teleneuron sense of discomfort, the promotion nerve injury, and side effect is less.The above results is the clinical data sufficient proof, and interrelated data is as follows, and wherein drugs uses and is the crude drug weight proportion among the embodiment 3.
1 object and method.
1.1 object: non-breaking property peripheral nerve injury 25 examples of in July, 2009 ~ 2011 year December.Occurrence cause consists of: wound or operation wound 13 examples (52.0%); Position is oppressed 10 examples (40.0%); Tourniquet is oppressed 2 examples (8.0).Common peroneal nerve 12 examples wherein, radial nerve 7 examples, median nerve 4 examples, ulnar nerve 2 examples.The innervation district feels to go down, disappearance or hyperesthesia, and muscular strength descends 0 ~ 3 grade, has 8 examples (32.0%) in various degree amyotrophy, neuratrophia to occur.
1.2 method.
1.2.1 grouping: non-breaking property peripheral nerve injury 24 examples are divided into treatment group 15 examples at random, matched group 10 examples.In treatment group 15 examples, male 11 examples, women 4 examples; 24～58 years old age, average 33.6 years old, in matched group 10 examples, male 7 examples, women 3 examples; 26～56 years old age, average 34.2 years old.Two groups of cases relatively, sex, age, nerve injury degree do not have notable difference (P〉0.05), have comparability.
1.2.2 Therapeutic Method: the matched group patient is according to circumstances to local nerve decompression, if have the adhesion strangulation then with the processing of loosening of neurosurgery means, clamping plate or stent support are taked in muscle and joint for the innervation zone, cooperate passive activity to carry out the exercise of limb function and range of motion.Treatment group adopts Chinese herbs decoction of the present invention to carry out innervation district hot-wet compress on the basis of matched group, every day twice, each 30min.Treat for two groups and be 4w the course for the treatment of.
1.2.3 clinical symptoms curative effect determinate standard: recovery from illness: motor function is recovered fully, 5 grades of muscular strengths, and numb, pain disappears; Produce effects: motor function is recovered substantially, and 4 grades of muscular strengths are without obvious numbness and paralgia; Effectively: motor function is partly recovered, 3 grades of muscular strengths, and numb pain alleviates; Invalid: as to change without obvious before and after the treatment.
1.2.4 electromyogram changes curative effect determinate standard: recovery from illness: check without unusual; Produce effects: electromyography is without/a little denervation current potential, visible potential of regeneration, and motor unit is mixed phase; Effectively: lose neuropotential and potential of regeneration, the motor unit minimizing is the simple mixing phase; Invalid: as to change without obvious before and after the treatment.
1.2.5 statistical analysis: carry out statistical analysis with SPSS 13.0, P＜0.05 expression has significant.
2 results.
2.1.1 the clinical symptoms curative effect of two groups of cases relatively sees the following form, recovery from illness and total effective rate treatment group obviously are better than matched group (P＜0.05).And in rehabilitation, the muscle adaptability for the treatment of group is better than matched group.
Relatively see the following form 2.1.2 the electromyogram of two groups of cases changes curative effect, cure rate and total effective rate treatment group obviously are better than matched group (P＜0.01).
3. conclusion.
Observe confirmation by clinical symptoms and electromyogram, topical application of the present invention can effectively reach the purpose of repairing after relaxed muscle, alleviation teleneuron sense of discomfort, the promotion nerve injury, and determined curative effect is worthy of promotion and application.
Claims (2)
1. one kind promotes the nursing soak liquid repaired after the nerve injury, it is characterized in that being processed by plurality of Chinese, its composition of raw materials and weight proportion are: 6 ~ 10 parts of Pseudobulbus Cremastrae Seu Pleioness, 8 ~ 15 parts of Fructus Forsythiaes, 8 ~ 15 parts of Caulis fici pumilae (Fructus Fici Pumilae)s, 6 ~ 10 parts of Ramulus et Folium Psychotriae Serpentis, 6 ~ 10 parts of Squama Maniss, 8 ~ 15 parts of Radix Angelicae Sinensis, 6 ~ 10 parts of Spica Prunellaes, 8 ~ 15 parts of Oleum Caryophyllis, 3 ~ 6 parts of Folium eucalypti globueli (Eucalyptus globulus Labill.)s.
2. a kind of nursing soak liquid of repairing after the nerve injury of promoting according to claim 1 is characterized in that its weight proportion is: 8 parts of Pseudobulbus Cremastrae Seu Pleioness, 10 parts of Fructus Forsythiaes, 10 parts of Caulis fici pumilae (Fructus Fici Pumilae)s, 8 parts of Ramulus et Folium Psychotriae Serpentis, 8 parts of Squama Maniss, 10 parts of Radix Angelicae Sinensis, 8 parts of Spica Prunellaes, 10 parts of Oleum Caryophyllis, 5 parts of Folium eucalypti globueli (Eucalyptus globulus Labill.)s.
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| CN103405648A (en) * | 2013-08-19 | 2013-11-27 | 陈霞 | A kind of external nursing material for ulnar nerve injury |
| CN103432385A (en) * | 2013-08-19 | 2013-12-11 | 庞尊钊 | A drug for repairing after peripheral nerve injury |
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| CN104706964A (en) * | 2013-08-19 | 2015-06-17 | 王刚刚 | Preparation method of mixed application for treating peripheral nerve injuries |
| CN104721567A (en) * | 2013-08-19 | 2015-06-24 | 陈霞 | Externally applied nursing dressing medicament after nerve injuries |
| CN104825671A (en) * | 2013-08-19 | 2015-08-12 | 曲良锁 | Method for preparing neural restoration postoperative externally-applied medicine |
| CN106215051A (en) * | 2016-08-31 | 2016-12-14 | 王东宝 | A kind of Chinese and Western compound medicine treating peripheral nerve injury and preparation method |
| CN108498605A (en) * | 2017-11-10 | 2018-09-07 | 姜燕 | A kind of pharmaceutical composition and its preparation method and application of anesthesia postoperative nerve nursing |
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| 王爱国等: "神经营养类中药的研究进展", 《第十四届全国中西医结合骨伤科学术研讨会论文集》 * |
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| CN103405648B (en) * | 2013-08-19 | 2015-04-08 | 陈霞 | A kind of external nursing material for ulnar nerve injury |
| CN103405650B (en) * | 2013-08-19 | 2015-04-15 | 王刚刚 | An external medicine for nerve injury caused by wrist trauma |
| CN103405651A (en) * | 2013-08-19 | 2013-11-27 | 陈霞 | Preparation method of ointment for ulnar nerve injury |
| CN103405650A (en) * | 2013-08-19 | 2013-11-27 | 王刚刚 | An external medicine for nerve injury caused by wrist trauma |
| CN103405648A (en) * | 2013-08-19 | 2013-11-27 | 陈霞 | A kind of external nursing material for ulnar nerve injury |
| CN103432385A (en) * | 2013-08-19 | 2013-12-11 | 庞尊钊 | A drug for repairing after peripheral nerve injury |
| CN103405649A (en) * | 2013-08-19 | 2013-11-27 | 刘建贞 | A kind of external pharmaceutical composition for rehabilitation after common peroneal nerve injury |
| CN103463419A (en) * | 2013-08-19 | 2013-12-25 | 庞尊钊 | Preparation method of ointment used for peripheral nerve injury postoperative repair |
| CN103393836A (en) * | 2013-08-19 | 2013-11-20 | 周建娣 | Preparation method of paste for curing paralysis of the radial nerve |
| CN104825671A (en) * | 2013-08-19 | 2015-08-12 | 曲良锁 | Method for preparing neural restoration postoperative externally-applied medicine |
| CN103432385B (en) * | 2013-08-19 | 2015-04-22 | 庞尊钊 | A drug for repairing after peripheral nerve injury |
| CN104706964A (en) * | 2013-08-19 | 2015-06-17 | 王刚刚 | Preparation method of mixed application for treating peripheral nerve injuries |
| CN104721567A (en) * | 2013-08-19 | 2015-06-24 | 陈霞 | Externally applied nursing dressing medicament after nerve injuries |
| CN103961555A (en) * | 2014-06-02 | 2014-08-06 | 刘惠平 | Traditional Chinese medicine preparation for treating peripheral nerve injury and preparation method thereof |
| CN106215051A (en) * | 2016-08-31 | 2016-12-14 | 王东宝 | A kind of Chinese and Western compound medicine treating peripheral nerve injury and preparation method |
| CN108498605A (en) * | 2017-11-10 | 2018-09-07 | 姜燕 | A kind of pharmaceutical composition and its preparation method and application of anesthesia postoperative nerve nursing |
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