CN102872244A - Burn and scald treatment medicament and preparation method thereof - Google Patents

Burn and scald treatment medicament and preparation method thereof Download PDF

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Publication number
CN102872244A
CN102872244A CN2012103637582A CN201210363758A CN102872244A CN 102872244 A CN102872244 A CN 102872244A CN 2012103637582 A CN2012103637582 A CN 2012103637582A CN 201210363758 A CN201210363758 A CN 201210363758A CN 102872244 A CN102872244 A CN 102872244A
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burn
chinese herbal
scald
herbal medicine
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CN102872244B (en
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艾尼瓦江·艾尔肯
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Abstract

The invention relates to the medical field, and especially relates to a burn and scald treatment medicament and a preparation method thereof. The raw materials of the medicament comprise an alcohol solution, Chinese herbal medicines and borneol, wherein the mass ratio of the alcohol solution to the Chinese herbal medicines is 1.5:1-2.5:1; the Chinese herbal medicines comprise, by mass, 750-1250 parts of rheum officinale, 750-1250 parts of garden burnet, 750-1250 parts of catechu, 250-750 parts of safflower, 750-1250 parts of phellodendron, 750-1250 parts of coptis chinensis, 750-1250 parts of scutellaria, 750-1250 parts of honeysuckle flower, and 750-1250 parts of elm bark; the medicament comprises 0.2-0.4 parts by mass of borneol. The method comprises the following steps: adding the Chinese herbal medicines into the alcohol solution, sealing and soaking at 25-40 DEG C for 14-16 days, and then adding the borneol. The burn and scald treatment medicament obtained by the preparation method of the invention can shorten the wound healing time.

Description

Curing burn and scald agent and preparation method thereof
Technical field
The present invention relates to medical field, particularly a kind of curing burn and scald agent and preparation method thereof.
Background technology
Body directly contacts high temp objects or is subject to the variation that strong heat radiation occurs.The damage that is caused by flame, high-temp solid and intense radiation heat is referred to as burn and scald.Burn and scald is the tissue injury that is caused by high temperature, chemical substance or electricity.The order of severity of burn and scald depends on the burn and scald degree of depth of wounded tissue, and the burn and scald degree of depth can be divided into I degree, II degree and III degree.
The damage of I degree burn and scald is the lightest.Burn and scald skin rubefaction, pain, obviously touch a tender spot, have and ooze out or edema.The part bleaches during light pressure injury, but does not have vesicle.
II degree burn and scald is divided into again light degree Ⅱ burn and scald and two kinds of dark II degree burn and scald.
The light degree Ⅱ burn and scald injures high dermis, and the part stratum germinativum is alive.Local red and swollen, vesicle not of uniform size is arranged, include the jelly of yellow or pale red blood plasma sample liquid or protein coagulation.If without complication such as infection, about 2 Zhou Keyu.More in a short time pigmentation can be arranged after, not stay cicatrix, skin function is good.
Dark II degree burn and scald injures below the papillary layer of corium, but still the residual fraction lamina reticularis.Local swelling, or have than phlysis.Because the appendages of skin such as remaining intradermal hair follicle, sweat glands, still renewable epithelium as without infecting, generally can heal in 3-4 week voluntarily.Can there be cicatrix and cicatrix to shrink the local function obstacle that causes after the healing.
The damage of III degree burn and scald is the darkest.Can turn white in the burn and scald surface, deliquescing or be black, carbonization hide-like.Become pale owing to burn skin, in the pale skin people, often be mistaken as normal skin, but no longer variable color during compressing.The erythrocyte that destroys can make the burn and scald local skin be cerise, and vesicle is arranged once in a while, and the hair in burn and scald district is easy to extract, and feels to go down.III degree burn and scald zone does not generally have the pain sensation.Because the teleneuron of skin is destroyed.Usually to through in a few days, could distinguish dark II degree and III degree burn and scald behind the burn and scald.
The medicine of existing treatment burn and scald all is the plaster of comparison thickness generally, during use plaster is applied at empyrosis wound surface, allows the efficacy of a drug be absorbed by wound surface, promotes body growth.But because the liquid in the plaster is less, cause flowability relatively poor, the efficacy of a drug wherein is difficult to fast transfer to wound surface, and the required time of fully recovering is longer.
Resolution of symptoms in the I degree empyrosis wound surface 2~3 days generally speaking, 3~5 days complete.If the light degree Ⅱ burn and scald is without infection, 1~2 week fully recovered.General 3~4 weeks recovery from illness of dark II degree burn and scald.III degree empyrosis wound surface 3~4 week eschar comes off, and needs to heal after the skin-grafting.
Summary of the invention
The invention provides a kind of curing burn and scald agent;
The present invention also provides a kind of preparation method of curing burn and scald agent.
Curing burn and scald agent that provides of the present invention and preparation method thereof can be shortened the burn and scald cure time.
In order to achieve the above object, technical scheme of the present invention is achieved in that
The curing burn and scald agent, its raw material comprises alcoholic solution, Chinese herbal medicine and Borneolum Syntheticum; Wherein,
The mass ratio of described alcoholic solution and described Chinese herbal medicine is 1.5:1~2.5:1;
Described Chinese herbal medicine comprises by mass: 750~1250 parts of Radix Et Rhizoma Rhei; 750~1250 parts of Radix Sanguisorbaes; 750~1250 parts in catechu; 250~750 parts on Flos Carthami; 750~1250 parts of Cortex Phellodendris; 750~1250 parts of Rhizoma Coptidis; 750~1250 parts of Radix Scutellariaes; 750~1250 parts of Flos Loniceraes; 750~1250 parts of Cortex ulmi pumilae;
Described Borneolum Syntheticum is 0.2~0.4 part by mass.
Further, in the aforesaid curing burn and scald agent, the mass concentration of described alcoholic solution is 75%~95%.
Further, in the aforesaid curing burn and scald agent, described Chinese herbal medicine comprises by mass: 900~1100 parts of Radix Et Rhizoma Rhei; 900~1100 parts of Radix Sanguisorbaes; 900~1100 parts in catechu; 400~600 parts on Flos Carthami; 900~1100 parts of Cortex Phellodendris; 900~1100 parts of Rhizoma Coptidis; 900~1100 parts of Radix Scutellariaes; 900~1100 parts of Flos Loniceraes; 900~1100 parts of Cortex ulmi pumilae.
Further, in the aforesaid curing burn and scald agent, the mass ratio of described alcoholic solution and described Chinese herbal medicine is 2:1.
Further, in the aforesaid curing burn and scald agent, described Borneolum Syntheticum is 0.25~0.35 part by mass.
The preparation method of curing burn and scald agent comprises the following steps:
Described Chinese herbal medicine is put into described alcoholic solution form mixed liquor;
Described mixed liquor was soaked 14~16 days at 25~40 ℃ of lower seals;
Described Borneolum Syntheticum added in the described mixed liquor dissolve;
Get the liquid in the described mixed liquor, obtain described curing burn and scald agent.
Further, in the preparation method of aforesaid curing burn and scald agent, before described Chinese herbal medicine being put into described alcoholic solution formation soak, further comprise:
With the Radix Et Rhizoma Rhei in the described Chinese herbal medicine, Radix Sanguisorbae, catechu, Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae and Cortex ulmi pumilae chopping.
Further, in the preparation method of aforesaid curing burn and scald agent, before described Chinese herbal medicine being put into described alcoholic solution formation soak, further comprise:
Respectively every kind of described Chinese herbal medicine is wrapped up with gauze.
Further, in the preparation method of aforesaid curing burn and scald agent, described step of getting the liquid in the described mixed liquor is specially:
Use drainage screen that described mixed liquor is filtered, get the filtrate after the filtration.
Further, in the preparation method of aforesaid curing burn and scald agent, with described soak in 25~40 ℃ of lower seals soak 14~16 days step, the soaking temperature of described soak is 30~35 ℃, soak time is 15 days.
Compared with prior art, curing burn and scald agent of the present invention and preparation method thereof mixes with alcoholic solution by the Chinese herbal medicine with multiple treatment burn and scald, and 25~40 ℃ of lower seals immersions 14~16 days, the ingredient in kind of the medical herbs is dissolved in the alcoholic solution.Have the Borneolum Syntheticum of antiinflammatory, detumescence effect and make its dissolving to soaking to add in the mixed liquor later more afterwards, the liquid that obtains so just can have the effect for the treatment of burn and scald.
In use, the curing burn and scald agent can be sprayed on the wound surface place, because medicament is liquid, so be easy to be absorbed by wound surface, wound surface can faster healing like this, thus the shortening cure time.
Description of drawings
In order to be illustrated more clearly in the specific embodiment of the invention or technical scheme of the prior art, the below will do to introduce simply to the accompanying drawing of required use in the specific embodiment or the description of the Prior Art, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain according to these accompanying drawings other accompanying drawing.
The preparation method flow chart of the curing burn and scald agent that Fig. 1 provides for the embodiment of the invention one;
The preparation method flow chart of the curing burn and scald agent that Fig. 2 provides for the embodiment of the invention two;
The preparation method flow chart of the curing burn and scald agent that Fig. 3 provides for the embodiment of the invention three;
The preparation method flow chart of the curing burn and scald agent that Fig. 4 provides for the embodiment of the invention four.
The specific embodiment
For making the purpose, technical solutions and advantages of the present invention clearer; the below will carry out clear, complete description to technical scheme of the present invention; based on the specific embodiment among the present invention; those of ordinary skills are resulting all other embodiments under the prerequisite of not making creative work, all belong to the scope that the present invention protects.
Embodiments of the invention one provide a kind of curing burn and scald agent, and its raw material comprises alcoholic solution, Chinese herbal medicine and the Borneolum Syntheticum of mass concentration 75%; Wherein,
The mass ratio of described alcoholic solution and described Chinese herbal medicine is 2.5:1;
Described Chinese herbal medicine comprises by mass: 750 parts of Radix Et Rhizoma Rhei; 750 parts of Radix Sanguisorbaes; 750 parts in catechu; 250 parts on Flos Carthami; 750 parts of Cortex Phellodendris; 750 parts of Rhizoma Coptidis; 750 parts of Radix Scutellariaes; 750 parts of Flos Loniceraes; 750 parts of Cortex ulmi pumilae;
Described Borneolum Syntheticum is 0.2 part by mass.
As shown in Figure 1, the preparation method of this curing burn and scald agent comprises the following steps:
101) described Chinese herbal medicine is put into described alcoholic solution and form mixed liquor;
102) described mixed liquor was soaked 14 days at 25 ℃ of lower seals;
103) described Borneolum Syntheticum is added in the described mixed liquor dissolve;
104) get liquid in the described mixed liquor, obtain described curing burn and scald agent.
Just can obtain having the curing burn and scald agent for the treatment of burn and scald effect by above-mentioned preparation method.
In use, the curing burn and scald agent can be sprayed on the wound surface place, because medicament is liquid, so be easy to be absorbed by wound surface, wound surface can faster healing like this, thus the shortening cure time.
In addition, traditional plaster causes wound surface to be hedged off from the outer world owing to can apply on wound surface when treatment, adds the thick characteristic of plaster itself, and wound site is not easy drying, is easy to breed bacteria and causes infection, further delays cure time.
And curing burn and scald agent provided by the invention is sprayed on the wound surface, wound surface is hedged off from the outer world, and the Rhizoma Coptidis that wherein contains can make the skin rapid draing of wound site, the antibacterial of outside can't enter the inner inflammation that causes, wound healing faster further shortened cure time.
Wound healing is a complicated pathological process, and the basis is a series of activities of inflammatory cell and repair cell.Inflammatory cell comprises: monokaryon, macrophage, and neutrophilic leukocyte, lymphocyte etc., repair cell comprises: fibroblast, endotheliocyte, epidermis cell etc.
Repair cell can make the wound surface normal growth, forms new skin; And the empyrosis wound surface infection can make inflammatory cell assemble at wound surface, makes the granulation tissue undue growth, forms cicatrix.
There is more TGF-β in Radix Scutellariae, Cortex Phellodendri and the catechu, the somatomedin such as bFGF and pDGF, these somatomedin can play to the activity of repair cell important regulating and controlling effect.They can be direct or indirect, acts on alone or synergistically repair cell, promotes the normal growth of skin, makes the rear preventing from scar of wound surface recovery from illness.
Radix Et Rhizoma Rhei, Radix Sanguisorbae, Flos Carthami, Flos Lonicerae, these five kinds of Chinese herbal medicine of Cortex ulmi pumilae can promote the blood flow of blood capillary, and abundant nutrient substance is delivered to wound surface, accelerate the growth of skin, shorten cure time.
Alcoholic solution not only can play the effect of dissolved substance composition, also can play bactericidal action after being sprayed into wound surface, prevents traumatic infection.
Can use different processing methods for the different burn and scald degree of depth:
The processing of I degree empyrosis wound surface: direct torch firing treatment of scald medicament on empyrosis wound surface, every day 2~3 times.
The processing of light degree Ⅱ empyrosis wound surface: direct torch firing treatment of scald medicament on empyrosis wound surface, the wound surface of vesicle is arranged, but low level break vesicle and discharge water, keep the bleb skin, removed the bleb skin after hindering in 3~4 days.Per 4~6 hours spray medicines once spray medicine front application antiseptic gauze or napkin at every turn wound surface left drug and exudate are wiped away only, generally healing after 6~7 days.Also can keep the bleb skin of breaking and directly spray medicine, until healing.
The processing of dark II degree empyrosis wound surface: press in early days the processing method treatment of light degree Ⅱ empyrosis wound surface, remove beancurd sheet after 5~6 days.In damaged condition because of dermal tissue, wound surface is white in color, and should continue torch firing treatment of scald medicament, and per 4 hours spray medicines once.After the medication, visible wound surface has the epidermal stem that occurs because of drug effect gradually, and the antibacterial of external environment can not be invaded subcutaneous tissue, protects hypodermic infection.But before it should be noted that each spray medicine, spray medicine after slough residual on the wound surface must being wiped away gently with antiseptic gauze or napkin, after about 6~7 days, slough is excluded again, and then continues as stated above treatment, until the flat skin healing of wound surface.
The processing of III degree empyrosis wound surface: available ploughing and weeding medicine changing knife is the dermatolysis of necrosis, then carry out the standard treatment according to dark II degree wound surface processing method, larger area III degree wound surface, in the stable situation of patient vital signs, after using first 1-2 days torch firing treatment of scald medicaments, subcutaneous tissue become done after, once removed downright bad subcutaneous tissue in per 2 days to 3 days, continuing torch firing treatment of scald medicament.
In the empyrosis wound surface processing procedure, should follow all the time three non-invasi treatment principles: the first, non-invasi ground early protection treatment wound surface avoids using any method that increases the weight of to damage or stimulate wound surface; The second, get rid of slough; The 3rd, non-invasi ground Regeneration and Repair skin avoids using the medicine that stimulates or damage wound surface.
In order further to improve the burn and scald therapeutic effect, embodiments of the invention two provide another kind of curing burn and scald agent, and its raw material comprises alcoholic solution, Chinese herbal medicine and the Borneolum Syntheticum of mass concentration 95%; Wherein,
The mass ratio of described alcoholic solution and described Chinese herbal medicine is 1.5:1;
Described Chinese herbal medicine comprises by mass: 1250 parts of Radix Et Rhizoma Rhei; 1250 parts of Radix Sanguisorbaes; 1250 parts in catechu; 750 parts on Flos Carthami; 1250 parts of Cortex Phellodendris; 1250 parts of Rhizoma Coptidis; 1250 parts of Radix Scutellariaes; 1250 parts of Flos Loniceraes; 1250 parts of Cortex ulmi pumilae;
Described Borneolum Syntheticum is 0.4 part by mass.
As shown in Figure 2, the preparation method of this curing burn and scald agent comprises the following steps:
201) described Chinese herbal medicine is put into described alcoholic solution and form mixed liquor;
202) described mixed liquor was soaked 14 days at 40 ℃ of lower seals;
203) described Borneolum Syntheticum is added in the described mixed liquor dissolve;
204) get liquid in the described mixed liquor, obtain described curing burn and scald agent.
At first, increased the weight of the deal of Chinese herbal medicine and Borneolum Syntheticum in the prescription that present embodiment provides, can make and contain more ingredient in the medicament.In addition, when sealing is soaked, use higher temperature, the ingredient in the Chinese herbal medicine can more be dissolved in the alcoholic solution, further improved the content of active component in the medicament.Therefore the curing burn and scald agent that provides of present embodiment possesses better therapeutic effect, can shorten cure time.
Embodiments of the invention three also provide another kind of curing burn and scald agent, and by carrying out method improvement, the situation of medical herbs consumption is issued to the therapeutic effect identical with embodiment two on the decrease.Its raw material comprises alcoholic solution, Chinese herbal medicine and the Borneolum Syntheticum of mass concentration 75%; Wherein,
The mass ratio of described alcoholic solution and described Chinese herbal medicine is 2:1;
Described Chinese herbal medicine comprises by mass: 900 parts of Radix Et Rhizoma Rhei; 900 parts of Radix Sanguisorbaes; 900 parts in catechu; 400 parts on Flos Carthami; 900 parts of Cortex Phellodendris; 900 parts of Rhizoma Coptidis; 900 parts of Radix Scutellariaes; 900 parts of Flos Loniceraes; 900 parts of Cortex ulmi pumilae;
Described Borneolum Syntheticum is 0.25 part by mass.
As shown in Figure 3, the preparation method of this curing burn and scald agent comprises the following steps:
301) with the Radix Et Rhizoma Rhei in the described Chinese herbal medicine, Radix Sanguisorbae, catechu, Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae and Cortex ulmi pumilae chopping;
302) described Chinese herbal medicine is put into described alcoholic solution and form mixed liquor;
303) described mixed liquor was soaked 16 days at 30 ℃ of lower seals;
304) described Borneolum Syntheticum is added in the described mixed liquor dissolve;
305) use drainage screen that described mixed liquor is filtered, get the filtrate after the filtration, obtain described curing burn and scald agent.
With putting into again alcoholic solution after Radix Et Rhizoma Rhei, Radix Sanguisorbae, catechu, Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae and the Cortex ulmi pumilae chopping, the tissue of its inside is directly contacted with alcoholic solution, its ingredient that contains can be dissolved in the liquid more fully, and utilization rate is higher.After using afterwards drainage screen to filter, filtrate just is the curing burn and scald agent.
In addition, embodiments of the invention four also provide another kind of curing burn and scald agent, and filling a prescription and method improvement by further in its basis at embodiment three, has again improved the therapeutic effect of curing burn and scald agent, and shortened preparation time.
The raw material of this curing burn and scald agent comprises that mass concentration is 95% alcoholic solution, Chinese herbal medicine and Borneolum Syntheticum; Wherein,
The mass ratio of described alcoholic solution and described Chinese herbal medicine is 2:1;
Described Chinese herbal medicine comprises by mass: 1100 parts of Radix Et Rhizoma Rhei; 1100 parts of Radix Sanguisorbaes; 1100 parts in catechu; Flos Carthami 600; 1100 parts of Cortex Phellodendris; 1100 parts of Rhizoma Coptidis; 1100 parts of Radix Scutellariaes; 1100 parts of Flos Loniceraes; 1100 parts of Cortex ulmi pumilae;
Described Borneolum Syntheticum is 0.35 part by mass.
As shown in Figure 4, the preparation method of this curing burn and scald agent comprises the following steps:
401) with the Radix Et Rhizoma Rhei in the described Chinese herbal medicine, Radix Sanguisorbae, catechu, Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae and Cortex ulmi pumilae chopping;
402) respectively every kind of described Chinese herbal medicine is wrapped up with gauze;
403) described Chinese herbal medicine is put into described alcoholic solution and form mixed liquor;
404) described mixed liquor was soaked 15 days at 35 ℃ of lower seals;
405) described Borneolum Syntheticum is added in the described mixed liquor dissolve;
406) get liquid in the described mixed liquor, obtain described curing burn and scald agent.
By on the basis of embodiment three, further increasing the deal of Chinese herbal medicine and Borneolum Syntheticum, can further improve the content of medicament Chinese medicine composition, improve therapeutic effect.Simultaneously, by before immersion, respectively every kind of described Chinese herbal medicine being wrapped up with gauze, can prevent that Chinese herbal medicine from disperseing in alcoholic solution.The bundle that directly takes out every kind of Chinese herbal medicine after immersion is finished from mixed liquor just can directly remain liquid.Remove the trouble of filtering from, saved preparation time.
The below uses the curing burn and scald agent of embodiment four preparations to carry out repeatedly clinical trial, and it is as follows specifically to test case:
Case one
The patient's name: Mt. Ai is bought and is carried Sha Li, male, the Uygur nationality, I degree burn.
Main suit: right side neck, right side chest, abdominal part, right side upper limb, right lateral thigh burn 10 days.
Medical history: patient's readme 10 days front right side necks of being admitted to hospital, right side chest, abdominal part, the right side upper limb, right lateral thigh is scalded by boiled water, and is local red and swollen, ache blister, movable difficulty, used at that time burn cream, effect is not good enough, limitation of activity, my Out-patient Department is medical hospitalizes undergraduate course take " burn " as diagnosis so suddenly send here, and spirit is not good enough in the rear course of disease of being admitted to hospital, and diet is good, it is poor to sleep, and two is just normal.
The Yecheng County is according to carrying wooden Kong Xiang commune hospital progress note
2012-9-12
Make the rounds of the wards today in patient's local swelling, pain, redness, the symptoms such as limitation of activity, vital sign is steady, and mind is clear, spirit is poor, and diet is general, and sleeping eyes are poor, human health screening: T:37 ℃ of P:88 time/minute R:22 time/minute Bp:100/70mmHg, laboratory examination is shown: routine blood test: WBC8.96 * 10 (9)/L, RBC4.55 * 10 (12)/L, HGB 133g/L, PLT 561 * 10 (9)/L,, routine urinalysis: no abnormality seen, stool routine examination: no abnormality seen, patient's symptom gives: Local Nursing Care, local spray medicine twice is total to 160g, antiinflammatory, the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-13
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as limitation of activity alleviated than the day before yesterday, and vital sign is steady, and spirit is poor, mind is clear, and diet is general, and it is poor to sleep, today, the patient felt sick, abdominal distention, heating, each arthralgia, weak, the symptoms such as poor appetite, so check hepatitis B two and half+c-hepatitis antibody today, liver function, kidney merit.Patient's symptom gives: continue Local Nursing Care, and local spray medicine twice, 160g strengthens antiinflammatory altogether, and the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-14
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as limitation of activity alleviated than the day before yesterday, weak, poor appetite, the symptoms such as each arthralgia take a turn for the better, vital sign is steady, and mind is clear, and spirit can, diet is general, and sleeping eyes are poor, and laboratory examination is shown: normal, patient's symptom gives: continue Local Nursing Care, local spray medicine once is total to 80g, strengthen antiinflammatory, the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-15
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as limitation of activity take a turn for the better, and today, the patient required to leave hospital, so today, the newspaper improvement was left hospital.
Treated altogether 4 days, scald is almost recovered, without obvious cicatrix.
Case two
She carries patient's name: A Budusala wood by rice, the male, and 2 years old, the Uygur nationality, light degree Ⅱ is scalded.
The main suit: " chest, abdominal part was scalded 1 hour by boiled water " is chief complaint and is admitted to hospital, and door is medical hospitalizes my section with " burn ".
Medical history: mother patient states front 1 hour chest at home of being admitted to hospital, abdominal part is scalded by boiled water, and is local red and swollen, aches, blister, limitation of activity was not used any Drug therapy and processing at that time, and my Out-patient Department is medical hospitalizes undergraduate course take " burn " as diagnosis so suddenly send here, spirit is not good enough in the rear course of disease of being admitted to hospital, diet is good, sleep can, two is just normal.
The Yecheng County is according to carrying wooden Kong Xiang commune hospital progress note
2012-9-2
It is local red and swollen in the patient to make the rounds of the wards today, pain, the symptoms such as movable difficulty, have a medical check-up: T:36.6 ℃ P:100 time/minute R:25 time/divide, laboratory examination is shown: routine blood test: WBC8.42 * 10 (9)/L, RBC4.58 * 10 (12)/L, HGB 124g/L, PLT291 * 10 (9)/L, routine urinalysis: normal, stool routine examination: normal, patient's symptom gives: Local Nursing Care, twice of local spray medicine, be total to 80g, antiinflammatory, the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-3
Make the rounds of the wards today local red and swollen in the patient, pain, the symptoms such as movable difficulty alleviated than the day before yesterday, spirit is poor, mind is clear, diet can, it is poor to sleep, today, the patient was nauseating, abdominal distention, and systemic pain is so check hepatitis B two half+c-hepatitis antibody today, liver function, kidney merit.Patient's symptom gives: continue Local Nursing Care, and local spray medicine twice, 80g strengthens antiinflammatory altogether, and nutrition treatment continues to observe change of illness state.
2012-9-4
Make the rounds of the wards today in patient's local redness, pain, the symptoms such as movable difficulty alleviated than the day before yesterday, abdominal distention, the symptoms such as systemic pain take a turn for the better, and vital sign is steady, mind is clear, spirit can, diet is general, sleeping eyes are poor, and laboratory examination is shown: normal, and patient's symptom gives: continue Local Nursing Care, continue spray medicine twice, 80g strengthens antiinflammatory altogether, the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-8
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as movable difficulty are more obvious alleviating than the day before yesterday, and have a medical check-up today: T:37 ℃ P:96 time/minute R:24 time/divide, vital sign is steady, mind is clear, spirit can, diet is poor, sleep can, patient's symptom gives: continue Local Nursing Care, twice of local spray medicine, be total to 80g, antiinflammatory, the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-10
Make the rounds of the wards today in patient's local redness, pain, the symptoms such as limitation of activity are clearly better, and mother patient requires to leave hospital, so quote institute today.
Treated altogether 9 days, scald is almost recovered, without obvious cicatrix.
Case three
The patient's name: wheat wheat Tours sweet-smelling grass Ai Hai carries male, 27 years old, the Uygur nationality, deepⅱdegreeburn.
The main suit: " right side neck, right side chest, abdominal part, right side upper limb, right lateral thigh burn 3 hours " is chief complaint and is admitted to hospital, and door is medical hospitalizes my section with " burn ".
Medical history: patient's readme 3 hours front right side necks of being admitted to hospital, right side chest, abdominal part, the right side upper limb, right lateral thigh is scalded by boiled water, and is local red and swollen, ache, blister, movable difficulty, my Out-patient Department is medical hospitalizes undergraduate course take " burn " as diagnosis so suddenly send here, spirit is not good enough in the rear course of disease of being admitted to hospital, diet is good, and it is poor to sleep, and two is just normal.
The Yecheng County is according to carrying wooden Kong Xiang commune hospital progress note
2012-8-28
Make the rounds of the wards today in patient's local swelling, pain, redness, the symptoms such as movable difficulty, vital sign is steady, and mind is clear, spirit is poor, diet is general, and sleeping eyes are poor, human health screening: T:36.6 ℃ of P:92 time/minute R:23 time/minute Bp:120/70mmHg, laboratory examination is shown: routine blood test: WBC18.58 * 10 (9)/L, RBC5.58 * 10 (12)/L, HGB 166g/L, PLT 395 * 10 (9)/L, routine urinalysis: no abnormality seen, stool routine examination: no abnormality seen, patient's symptom gives: Local Nursing Care, local spray medicine three times, be total to 200g, antiinflammatory, the nutrition symptomatic treatment continues to observe change of illness state.
2012-8-29
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as movable difficulty alleviated than the day before yesterday, and vital sign is steady, and spirit is poor, mind is clear, and diet is general, and it is poor to sleep, today, the patient felt sick, abdominal distention, heating, each arthralgia, weak, the symptoms such as poor appetite, so check hepatitis B two and half+c-hepatitis antibody today, liver function, kidney merit.Patient's symptom gives: continue Local Nursing Care, and local spray medicine three times, 200g strengthens antiinflammatory altogether, and the nutrition symptomatic treatment continues to observe change of illness state.
2012-8-30
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as movable difficulty alleviated than the day before yesterday, weak, poor appetite, the symptoms such as each arthralgia take a turn for the better, vital sign is steady, and mind is clear, and spirit can, diet is general, and sleeping eyes are poor, and laboratory examination is shown: normal, patient's symptom gives: continue Local Nursing Care, local spray medicine three times, altogether 200g, strengthen antiinflammatory, the nutrition symptomatic treatment continues to observe change of illness state.
2012-9-5
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as movable difficulty are more obvious alleviating than the day before yesterday, and today, laboratory examination was shown: routine blood test: WBC18.58 * 10 (9)/L, RBC5.58 * 10 (12)/L, HGB166g/L, PLT 395 * 10 (9)/L, vital sign is steady, mind is clear, spirit can, diet is poor, sleep can, continue Local Nursing Care, local spray medicine three times, 200g continues anti-inflammatory treatment altogether, continues to observe change of illness state.
2012-9-7
Make the rounds of the wards today in patient's local swelling, redness, pain, the symptoms such as movable difficulty are clearly better, and today, the patient required to leave hospital, so today, the newspaper improvement was left hospital.
Treated altogether 11 days, burn is almost recovered, without obvious cicatrix.
Case four
The patient's name: the Yi Bulayi wooden block closes carries Ba Ke, male, 30 years old, the Uygur nationality, III degree burn.
The main suit: " neck, the bilateral arm was by fire burn 17 days " is chief complaint and hospitalizes my section with " burn " into gate is medical.
Medical history: mother patient states the front 17 days necks at home of being admitted to hospital, and the bilateral arm is by fire burn, and is local red and swollen, ache blister, limitation of activity, the anxious Hotan Prefecture's hospital of delivering to was treated at that time, give patient blood transfusion in the therapeutic process, local bag is hindered, but effect is not good enough, so come my institute today, outpatient clinic is hospitalized undergraduate course take " burn " as diagnosis, and spirit is not good enough in the rear course of disease of being admitted to hospital, and diet is good.Sleep can.Two is just normal.
The Yecheng County is according to carrying wooden Kong Xiang commune hospital progress note
2012-8-25
It is local red and swollen in the patient to make the rounds of the wards today, pain, the symptoms such as limitation of activity, vital sign is steady, haves a medical check-up: T:37.0 ℃ of P:92 time/minute R:23 time/minute Bp:110/80mmHg, and laboratory examination is shown: routine blood test: WBC5.44 * 10 (9)/L, RBC4.51 * 10 (12)/L, HGB 121g/L, PLT 681 * 10 (9)/L, routine urinalysis: normal, stool routine examination: no abnormality seen, continue Local Nursing Care, spray medicine three times, 400g strengthens anti-inflammatory treatment altogether, continues to observe change of illness state.
2012-8-26
Make the rounds of the wards today local red and swollen in the patient, pain, the symptoms such as limitation of activity alleviated than the day before yesterday, spirit is poor, mind is clear, diet can, it is poor to sleep, today, the patient was nauseating, and each arthralgia is so check hepatitis B two half+c-hepatitis antibody today, liver function, kidney merit, electrolyte.Local spray medicine three times, 200g strengthens anti-inflammatory treatment altogether, continues to observe change of illness state.
2012-8-27
Make the rounds of the wards today in patient's local redness, pain, the symptoms such as limitation of activity alleviated than the day before yesterday, vital sign is steady, T:37.0 ℃ of P:92 time/minute R:23 time/minute Bp:110/80mmHg, and mind is clear, spirit can, diet is general, sleeping eyes are poor, and hepatitis B two half+c-hepatitis antibody is shown in laboratory examination, liver function, kidney merit, electrolyte: no abnormality seen, continue Local Nursing Care, continue the spray medicine three times, 200g strengthens anti-inflammatory treatment altogether, continues to observe change of illness state.
2012-8-31
Make the rounds of the wards today in patient's local redness, pain, the symptoms such as limitation of activity are more obvious alleviating than the day before yesterday, have a medical check-up today: T:37.0 ℃ of P:92 time/minute R:23 time/minute Bp:110/80mmHg, mind is clear, spirit can, diet is poor, sleep can, continue Local Nursing Care, spray medicine three times, altogether 200g, continue antiinflammatory, continue to observe change of illness state.
2012-9-4
Make the rounds of the wards today in patient's local redness, pain, the symptoms such as limitation of activity are clearly better, and vital sign is steady, and patient's mind is clear, spirit can, diet can, sleeping eyes can, T:37.0 ℃ P:92 time/minute R:23 time/divide Bp:110/80mmHg. routine blood test: WBC6.75 * 10 (9)/L, RBC4.58 * 10 (12)/L, HGB126g/L, PLT 339 * 10 (9)/L, two is just normal, without heating, continue Local Nursing Care, continue the spray medicine three times, altogether 200g, strengthen anti-inflammatory treatment, continue to observe change of illness state.
2012-9-7
Make the rounds of the wards today local red and swollen in the patient, pain, the symptoms such as limitation of activity are clearly better, vital sign is steady, patient's mind is clear, spirit can, diet can, sleeping eyes can, two is just normal, without heating.The patient requires to leave hospital, so quote institute today.
Treated altogether 14 days, burn is almost recovered, without obvious cicatrix.
Confirmed that by above clinical trial curing burn and scald agent provided by the present invention all has preferably effect for curing various burn and scald, the patient just can be almost recovered within two weeks, the weak point of comparing with existing cure time.And not having obvious cicatrix, the skin growth of wound site is better.
It should be noted that at last: above embodiment and embodiment only in order to technical scheme of the present invention to be described, are not intended to limit; Although with reference to aforementioned embodiments and embodiment the present invention is had been described in detail, those of ordinary skill in the art is to be understood that: it still can be made amendment to the technical scheme that aforementioned embodiments or embodiment put down in writing, and perhaps part technical characterictic wherein is equal to replacement; And these modifications or replacement do not make the essence disengaging embodiment of the present invention of appropriate technical solution or the spirit and scope of embodiment technical scheme.

Claims (10)

1. curing burn and scald agent is characterized in that: its raw material comprises alcoholic solution, Chinese herbal medicine and Borneolum Syntheticum; Wherein,
The mass ratio of described alcoholic solution and described Chinese herbal medicine is 1.5:1~2.5:1;
Described Chinese herbal medicine comprises by mass: 750~1250 parts of Radix Et Rhizoma Rhei; 750~1250 parts of Radix Sanguisorbaes; 750~1250 parts in catechu; 250~750 parts on Flos Carthami; 750~1250 parts of Cortex Phellodendris; 750~1250 parts of Rhizoma Coptidis; 750~1250 parts of Radix Scutellariaes; 750~1250 parts of Flos Loniceraes; 750~1250 parts of Cortex ulmi pumilae;
Described Borneolum Syntheticum is 0.2~0.4 part by mass.
2. curing burn and scald agent as claimed in claim 1 is characterized in that: the mass concentration of described alcoholic solution is 75%~95%.
3. curing burn and scald agent as claimed in claim 1, it is characterized in that: described Chinese herbal medicine comprises by mass: 900~1100 parts of Radix Et Rhizoma Rhei; 900~1100 parts of Radix Sanguisorbaes; 900~1100 parts in catechu; 400~600 parts on Flos Carthami; 900~1100 parts of Cortex Phellodendris; 900~1100 parts of Rhizoma Coptidis; 900~1100 parts of Radix Scutellariaes; 900~1100 parts of Flos Loniceraes; 900~1100 parts of Cortex ulmi pumilae.
4. curing burn and scald agent as claimed in claim 1 is characterized in that: the mass ratio of described alcoholic solution and described Chinese herbal medicine is 2:1.
5. curing burn and scald agent as claimed in claim 1 is characterized in that: described Borneolum Syntheticum is 0.25~0.35 part by mass.
6. the preparation method of the described curing burn and scald agent of any one in the claim 1 to 5 is characterized in that, comprises the following steps:
Described Chinese herbal medicine is put into described alcoholic solution form mixed liquor;
Described mixed liquor was soaked 14~16 days at 25~40 ℃ of lower seals;
Described Borneolum Syntheticum added in the described mixed liquor dissolve;
Get the liquid in the described mixed liquor, obtain described curing burn and scald agent.
7. the preparation method of curing burn and scald agent as claimed in claim 6 is characterized in that, further comprises before described Chinese herbal medicine being put into described alcoholic solution formation soak:
With the Radix Et Rhizoma Rhei in the described Chinese herbal medicine, Radix Sanguisorbae, catechu, Cortex Phellodendri, Rhizoma Coptidis, Radix Scutellariae and Cortex ulmi pumilae chopping.
8. such as the preparation method of claim 6 or 7 described curing burn and scald agent, it is characterized in that, before described Chinese herbal medicine being put into described alcoholic solution formation soak, further comprise:
Respectively every kind of described Chinese herbal medicine is wrapped up with gauze.
9. such as the preparation method of claim 6 or 7 described curing burn and scald agent, it is characterized in that described step of getting the liquid in the described mixed liquor is specially:
Use drainage screen that described mixed liquor is filtered, get the filtrate after the filtration.
10. the preparation method of curing burn and scald agent as claimed in claim 6 is characterized in that, with described soak in 25~40 ℃ of lower seals soak 14~16 days step, the soaking temperature of described soak is 30~35 ℃, soak time is 15 days.
CN201210363758.2A 2012-09-26 2012-09-26 Burn and scald treatment medicament and preparation method thereof Expired - Fee Related CN102872244B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103735699A (en) * 2014-01-24 2014-04-23 张代增 Traditional Chinese medicinal composition for treating scald and preparation method thereof
CN105395873A (en) * 2015-12-10 2016-03-16 韦邦力 Composition for treating slight burns and scalds
CN116173113A (en) * 2023-02-14 2023-05-30 江苏春江生物科技有限公司 Medicament for treating burns and scalds and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1795904A (en) * 2004-12-29 2006-07-05 吴宏录 Spray agent for burn and scald
CN101024001A (en) * 2007-04-13 2007-08-29 张现洪 Burn spraying medicine preparation
CN102028793A (en) * 2010-11-19 2011-04-27 黄文扬 Traditional Chinese medicinal composition for treating burns and scalding

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1795904A (en) * 2004-12-29 2006-07-05 吴宏录 Spray agent for burn and scald
CN101024001A (en) * 2007-04-13 2007-08-29 张现洪 Burn spraying medicine preparation
CN102028793A (en) * 2010-11-19 2011-04-27 黄文扬 Traditional Chinese medicinal composition for treating burns and scalding

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103735699A (en) * 2014-01-24 2014-04-23 张代增 Traditional Chinese medicinal composition for treating scald and preparation method thereof
CN103735699B (en) * 2014-01-24 2016-04-20 张代增 A kind of Chinese medicine composition for the treatment of scald and preparation method thereof
CN105395873A (en) * 2015-12-10 2016-03-16 韦邦力 Composition for treating slight burns and scalds
CN116173113A (en) * 2023-02-14 2023-05-30 江苏春江生物科技有限公司 Medicament for treating burns and scalds and preparation method thereof

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